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Adam, AC; Grohe, C; Stier, S; Gattenlohner, S; Balta, Z; Buttner, R; Gutgemann, I.
Hodgkin's lymphoma in a patient with Jo-1 syndrome.
Virchows Arch. 2007; 451(1):101-104
Doi: 10.1007/s00428-007-0429-0
(- Case Report)
Web of Science
PubMed
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- Co-authors Med Uni Graz
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Gattenlöhner Stefan
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- Abstract:
- Jo-1 syndrome is an autoimmune disease with autoantibodies against the histidyl tRNA synthetase. Characteristic clinical findings include inflammatory myopathy and interstitial lung disease. We present the first case of a patient with Jo-1 syndrome (positive Jo-1 autoantibodies, myositis, interstitial alveolitis) who developed Hodgkin's lymphoma of nodular-sclerosing type. Thus, patients with Jo-1 syndrome and immunosuppressive therapy similar to other patients with autoimmune disease are at risk to develop lymphomas and should therefore be monitored carefully.
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Antibodies, Antinuclear - blood
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Antibodies, Viral - blood
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Hodgkin Disease - etiology
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Humans -
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Immunohistochemistry -
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Male -
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Middle Aged -
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Myositis - complications
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Pulmonary Fibrosis - complications
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Receptors, Antigen, T-Cell, gamma-delta - genetics
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Syndrome -
- Find related publications in this database (Keywords)
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anti-synthetase-syndrome
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Jo-1 syndrome
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Hodgkin's lymphoma
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myositis
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alveolitis