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SHR Neuro Cancer Cardio Lipid Metab Microb

Wagner, AD; Dejaco, C.
Emergencies in Rheumatology: Giant Cell Arteritis with Visual Symptoms, Vertebrobasilar Insufficiency or Other Ischaemic Complications
AKTUEL RHEUMATOL. 2010; 35(1): 43-48. Doi: 10.1055/s-0029-1243165
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Co-authors Med Uni Graz: Dejaco Christian
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Abstract:: Giant cell arteritis (GCA) is the most common systemic vasculitis and affects large and medium-sized vessels. Emergencies can occur in the course of GCA because the disease may cause arterial stenosis and/or aneurysm formation. The most common complication of GCA is ischaemia of the optic nerve causing irreversible blindness. Besides, dissection of aortic aneurysm, cerebral ischaemia, ischaemia of limbs or organs as well as tongue necrosis may occur. Diagnosis of GCA including biopsy of the temporal artery should be performed as soon as possible; however, therapy should not be delayed due to a lacking biopsy result. Corticosteroids are the therapy of choice in the treatment of GCA, disease-modifying drugs, particularly methotrexate, may have a corticosteroid-sparing effect.
Find related publications in this database (Keywords): vasculitis; giant cell arteritis; emergencies; ischaemic complications