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SHR Neuro Cancer Cardio Lipid Metab Microb

Ferré, S; Baler, R; Bouvier, M; Caron, MG; Devi, LA; Durroux, T; Fuxe, K; George, SR; Javitch, JA; Lohse, MJ; Mackie, K; Milligan, G; Pfleger, KD; Pin, JP; Volkow, ND; Waldhoer, M; Woods, AS; Franco, R.
Building a new conceptual framework for receptor heteromers.
Nat Chem Biol. 2009; 5(3): 131-134. Doi: 10.1038/nchembio0309-131 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Co-authors Med Uni Graz
Waldhoer Maria
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Abstract:
Receptor heteromers constitute a new area of research that is reshaping our thinking about biochemistry, cell biology, pharmacology and drug discovery. In this commentary, we recommend clear definitions that should facilitate both information exchange and research on this growing class of transmembrane signal transduction units and their complex properties. We also consider research questions underlying the proposed nomenclature, with recommendations for receptor heteromer identification in native tissues and their use as targets for drug development.
Find related publications in this database (using NLM MeSH Indexing)
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