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SHR Neuro Cancer Cardio Lipid Metab Microb

Bettinger, D; Berzigotti, A; Mandorfer, M; Ripoll, C; Labenz, C; Zizer, E; Bruns, T; De Gottardi, A; Emrich, J; Engelmann, C; Maasoumy, B; Ferlitsch, A; Fuhrmann, V; Hinrichs, J; Jansen, C; Lackner, K; Matzberger, R; Meyer, C; Mozayani, B; Praktiknjo, M; Reuken, PA; Schultheiss, M; Zipprich, A; Lange, CM; Kloeckner, R; Sarrazin, C; Trebicka, J; Reiberger, T; Bosch, J; Dollinger, MM.
Transjugular diagnostic procedures in hepatology: Indications, techniques and interpretation
JHEP REP. 2025; 7(8): 101437 Doi: 10.1016/j.jhepr.2025.101437 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Co-authors Med Uni Graz

Lackner Karoline

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Abstract:

Measurement of the hepatic venous pressure gradient (HVPG) and transjugular liver biopsy have emerged as important tools in clinical hepatology. Measurement of HVPG is considered the gold standard for detecting clinically significant portal hypertension, with an HVPG of >= 10 mmHg being the key prognostic threshold in patients with compensated advanced chronic liver disease (cACLD; compensated cirrhosis). A transjugular liver biopsy can be obtained within the same procedure and may be preferred over percutaneous liver biopsy in patients with coagulopathy, ascites and/or significant obesity. Endoscopic ultrasound-guided procedures are currently under investigation and require standardisation. This article summarises critical technical aspects of HVPG measurements and transjugular liver biopsy and provides a detailed overview of their current role in the context of emerging noninvasive tests and endoscopic approaches. (c) 2025 The Author(s). Published by Elsevier B.V. on behalf of European Association for the Study of the Liver (EASL). This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Find related publications in this database (Keywords)

Cirrhosis

porto-sinusoidal vascular disorder

PSVD

portal hypertension

hepatic venous pressure gradient

HVPG

transjugular liver biopsy

minimally invasive

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