Selected Publication:

SHR Neuro Cancer Cardio Lipid Metab Microb

Dinnie, Y; Everson, F; Kamau, FM; Webster, I; Kgokane, B; De Boever, P; Goswami, N; Strijdom, H.
The temporal relationship between body composition and cardiometabolic profiles in an HIV-infected (on antiretroviral therapy) versus HIV-free Western Cape study population
CARDIOVASC J AFR. 2024; Doi: 10.5830/CVJA-2024-005
Web of Science PubMed FullText FullText_MUG

 

Co-authors Med Uni Graz

Goswami Nandu

Altmetrics:

Dimensions Citations:

Plum Analytics:

Scite (citation analytics):

Abstract:

Cardiovascular risk is a health concern in people living with HIV/AIDS (PLWH). This longitudinal study (baseline vs 36 months) aimed to investigate the relationship between body composition and markers of cardiovascular risk in a South African study population [HIV free, n = 22 vs HIV positive on antiretroviral therapy (HIV+ART), n = 73)]. Health questionnaires, anthropometric measurements, biochemical analyses and flow-mediated dilation were performed. Linear mixed-model statistical analyses were applied. The HIV+ART vs the HIV-free groups were independently associated with body mass index (BMI) [-4.92 (-7.99 to -1.84), p = 0.002] and waist circumference [-10.5 (-17.2 to -3.77), p = 0.003]. ART duration was associated with BMI [2.60 (0.57-4.62), p = 0.013], waist circumference [3.83 (0.03-7.63), p = 0.048] and high-density lipoprotein cholesterol [20.18 (2.37-41.09), p = 0.025]. The data showed that intricate relationships existed in this study population between HIV, ART, body composition and cardiometabolic variables. There is a need for more research investigating cardiovascular risk in PLWH, particularly in the context of changes in body composition measures.

Find related publications in this database (Keywords)

body composition

body mass index

waist circumfer- ence

HIV/AIDS

cardiovascular risk

antiretroviral therapy

© Med Uni Graz • Imprint