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SHR Neuro Cancer Cardio Lipid Metab Microb

Bassetti, M; Giacobbe, DR; Agvald-Ohman, C; Akova, M; Alastruey-Izquierdo, A; Arikan-Akdagli, S; Azoulay, E; Blot, S; Cornely, OA; Cuenca-Estrella, M; de, Lange, DW; De, Rosa, FG; De, Waele, JJ; Dimopoulos, G; Garnacho-Montero, J; Hoenigl, M; Kanj, SS; Koehler, P; Kullberg, BJ; Lamoth, F; Lass-Flörl, C; Maertens, J; Martin-Loeches, I; Muñoz, P; Poulakou, G; Rello, J; Sanguinetti, M; Taccone, FS; Timsit, JF; Torres, A; Vazquez, JA; Wauters, J; Asperges, E; Cortegiani, A; Grecchi, C; Karaiskos, I; Le, Bihan, C; Mercier, T; Mortensen, KL; Peghin, M; Rebuffi, C; Tejada, S; Vena, A; Zuccaro, V; Scudeller, L; Calandra, T, , Study, Group, for, Infections, in, Critically, Ill, Patients, of, the, European, Society, of, Clinical, Microbiology, and, Infectious, Diseases, (ESGCIP), the, Fungal, Infection, Study, Group, of, the, European, Society, of, Clinical, Microbiology, and, Infectious, Diseases, (EFISG), the, European, Society, of, Intensive, Care, Medicine, (ESICM), the, European, Confederation, of, Medical, Mycology, (ECMM), the, Mycoses, Study, Group, Education, and, Research, Consortium, (MSGERC), the, International, Society, of, Antimicrobial, Chemotherapy, (ISAC), the, International, Society, for, Human, and, Animal, Mycology, (ISHAM), the, Austrian, Society, for, Medical, Mycology, (ÖGMM), the, Italian, Society, of, Anesthesia, Analgesia, Reanimation, and, Intensive, Care, (SIAARTI), the, Italian, Society, of, Anti-Infective, Therapy, (SITA), and, the, FUNDICU, Collaborators.
Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM.
Intensive Care Med. 2024; 50(4):502-515 Doi: 10.1007/s00134-024-07341-7 [OPEN ACCESS]
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Co-authors Med Uni Graz

Hönigl Martin

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Abstract:

PURPOSE: The aim of this document was to develop standardized research definitions of invasive fungal diseases (IFD) in non-neutropenic, adult patients without classical host factors for IFD, admitted to intensive care units (ICUs). METHODS: After a systematic assessment of the diagnostic performance for IFD in the target population of already existing definitions and laboratory tests, consensus definitions were developed by a panel of experts using the RAND/UCLA appropriateness method. RESULTS: Standardized research definitions were developed for proven invasive candidiasis, probable deep-seated candidiasis, proven invasive aspergillosis, probable invasive pulmonary aspergillosis, and probable tracheobronchial aspergillosis. The limited evidence on the performance of existing definitions and laboratory tests for the diagnosis of IFD other than candidiasis and aspergillosis precluded the development of dedicated definitions, at least pending further data. The standardized definitions provided in the present document are aimed to speed-up the design, and increase the feasibility, of future comparative research studies.

Find related publications in this database (using NLM MeSH Indexing)

Adult - administration & dosage

Humans - administration & dosage

Consensus - administration & dosage

Invasive Fungal Infections - diagnosis

Aspergillosis - diagnosis

Candidiasis, Invasive - diagnosis

Intensive Care Units - administration & dosage

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Invasive fungal diseases

Aspergillus

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Consensus

Definitions

Diagnosis

Intensive care unit

Research

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