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SHR Neuro Cancer Cardio Lipid Metab Microb

Chang, CC; Harrison, TS; Bicanic, TA; Chayakulkeeree, M; Sorrell, TC; Warris, A; Hagen, F; Spec, A; Oladele, R; Govender, NP; Chen, SC; Mody, CH; Groll, AH; Chen, YC; Lionakis, MS; Alanio, A; Castañeda, E; Lizarazo, J; Vidal, JE; Takazono, T; Hoenigl, M; Alffenaar, JW; Gangneux, JP; Soman, R; Zhu, LP; Bonifaz, A; Jarvis, JN; Day, JN; Klimko, N; Salmanton-García, J; Jouvion, G; Meya, DB; Lawrence, D; Rahn, S; Bongomin, F; McMullan, BJ; Sprute, R; Nyazika, TK; Beardsley, J; Carlesse, F; Heath, CH; Ayanlowo, OO; Mashedi, OM; Queiroz-Telles, Filho, F; Hosseinipour, MC; Patel, AK; Temfack, E; Singh, N; Cornely, OA; Boulware, DR; Lortholary, O; Pappas, PG; Perfect, JR.
Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM.
Lancet Infect Dis. 2024; 24(8):e495-e512 Doi: 10.1016/S1473-3099(23)00731-4 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

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Hönigl Martin

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Abstract:

Cryptococcosis is a major worldwide disseminated invasive fungal infection. Cryptococcosis, particularly in its most lethal manifestation of cryptococcal meningitis, accounts for substantial mortality and morbidity. The breadth of the clinical cryptococcosis syndromes, the different patient types at-risk and affected, and the vastly disparate resource settings where clinicians practice pose a complex array of challenges. Expert contributors from diverse regions of the world have collated data, reviewed the evidence, and provided insightful guideline recommendations for health practitioners across the globe. This guideline offers updated practical guidance and implementable recommendations on the clinical approaches, screening, diagnosis, management, and follow-up care of a patient with cryptococcosis and serves as a comprehensive synthesis of current evidence on cryptococcosis. This Review seeks to facilitate optimal clinical decision making on cryptococcosis and addresses the myriad of clinical complications by incorporating data from historical and contemporary clinical trials. This guideline is grounded on a set of core management principles, while acknowledging the practical challenges of antifungal access and resource limitations faced by many clinicians and patients. More than 70 societies internationally have endorsed the content, structure, evidence, recommendation, and pragmatic wisdom of this global cryptococcosis guideline to inform clinicians about the past, present, and future of care for a patient with cryptococcosis.

Find related publications in this database (using NLM MeSH Indexing)

Humans - administration & dosage

Cryptococcosis - diagnosis, drug therapy

Antifungal Agents - therapeutic use

Practice Guidelines as Topic - administration & dosage

Global Health - administration & dosage

Meningitis, Cryptococcal - diagnosis, drug therapy

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