Selected Publication:

SHR Neuro Cancer Cardio Lipid Metab Microb

Windpessl, M; Odler, B; Bajema, IM; Geetha, D; Säemann, M; Lee, JM; Vaglio, A; Kronbichler, A.
Glomerular Diseases Across Lifespan: Key Differences in Diagnostic and Therapeutic Approaches.
Semin Nephrol. 2023; 43(4):151435 Doi: 10.1016/j.semnephrol.2023.151435
Web of Science PubMed FullText FullText_MUG

 

Co-authors Med Uni Graz

Odler Balazs

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Abstract:

Glomerular diseases are common causes of chronic kidney disease in childhood, adolescence, and adulthood. The epidemiology of glomerular diseases differs between different age groups, with minimal change disease being the leading cause of nephrotic syndrome in childhood, while membranous nephropathy and focal segmental glomerulosclerosis are more common in adulthood. IgA vasculitis is also more common in childhood. Moreover, there is a difference in disease severity with more children presenting with a relapsing form of nephrotic syndrome and a more acute presentation of antineutrophil cytoplasmic antibody-associated vasculitis and concomitant glomerulonephritis, as highlighted by the higher percentage of cellular crescents on kidney biopsy specimens in comparison with older patients. There is also a female preponderance in antineutrophil cytoplasmic antibody-associated vasculitis and more children present with tracheobroncholaryngeal disease. This article aims to summarize differences in the presentation of different glomerular diseases that are encountered commonly by pediatric and adult nephrologists and potential differences in the management.

Find related publications in this database (using NLM MeSH Indexing)

Adult - administration & dosage

Adolescent - administration & dosage

Humans - administration & dosage

Female - administration & dosage

Child - administration & dosage

Nephrotic Syndrome - administration & dosage

Longevity - administration & dosage

Antibodies, Antineutrophil Cytoplasmic - administration & dosage

Glomerulonephritis - diagnosis, epidemiology, therapy

Glomerulonephritis, Membranous - diagnosis, epidemiology, therapy

Renal Insufficiency, Chronic - pathology

Vasculitis - pathology

Biopsy - administration & dosage

Glomerulonephritis, IGA - epidemiology

Kidney - pathology

Find related publications in this database (Keywords)

Glomerular diseases

podocytopathies

AAV

lupus nephritis

C3 glomerulonephritis

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