Medizinische Universität Graz - Research portal

Selected Publication:

SHR Neuro Cancer Cardio Lipid Metab Microb

Lindenmann, J; Porubsky, C; Okresa, L; Klemen, H; Mykoliuk, I; Roj, A; Koutp, A; Kink, E; Iberer, F; Kovacs, G; Krause, R; Smolle, J; Smolle-Juettner, FM.
Immediate and Long-Term Effects of Hyperbaric Oxygenation in Patients with Long COVID-19 Syndrome Using SF-36 Survey and VAS Score: A Clinical Pilot Study.
J Clin Med. 2023; 12(19): Doi: 10.3390/jcm12196253 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Leading authors Med Uni Graz
Lindenmann Jörg
Co-authors Med Uni Graz
Iberer Florian
Klemen Huberta
Koutp Amir
Kovacs Gabor
Krause Robert
Mykoliuk Iurii
Okresa Lucija
Porubsky Christian
Roj Andrej
Smolle Josef
Smolle-Juettner Freyja-Maria
Altmetrics:

Dimensions Citations:

Plum Analytics:

Scite (citation analytics):

Abstract:
(1) Background: Long COVID syndrome (LCS) is a heterogeneous long-standing condition following COVID-19 infection. Treatment options are limited to symptomatic measures, and no specific medication has been established. Hyperbaric oxygenation (HBO) has been found to have a positive impact on the treatment of COVID-19 infection. This study evaluates both the feasibility and outcome of supportive HBO in patients with LCS. (2) Methods: Within 17 months, 70 patients with proven LCS were prospectively included. Each patient underwent a cycle of 10 subsequent HBO treatment sessions administered for 75 min at 2.2 atmospheres. Evaluation of the patients was performed before the first and after the last HBO session and 3 months afterwards. Statistical evaluation was based on an intention-to-treat analysis using Fisher's exact test and Student's t-test for paired samples. (3) Results: In total, 59 patients (33 females, 26 males; mean age: 43.9 years; range: 23-74 years; median: 45.0) were evaluable. After HBO, a statistically significant improvement of physical functioning (p < 0.001), physical role (p = 0.01), energy (p < 0.001), emotional well-being (p < 0.001), social functioning (p < 0.001), pain (p = 0.01) and reduced limitation of activities (p < 0.001) was confirmed. (4) Conclusions: Physical functioning and both the physical and emotional role improved significantly and sustainably, suggesting HBO as a promising supportive therapeutic tool for the treatment of LCS.

Find related publications in this database (Keywords)
long COVID
hyperbaric oxygenation
long-term effect
improvement
physical function
pain
fatigue
energy
general perception of health
© Med Uni GrazImprint