Selected Publication:

SHR Neuro Cancer Cardio Lipid Metab Microb

Cosentino, F; Osto, E.
Aging and endothelial dysfunction.
Clin Hemorheol Microcirc. 2007; 37(1-2):143-7
Web of Science PubMed

 

Co-authors Med Uni Graz

Osto Elena

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Abstract:

Aging is the major risk factor for the development of cardiovascular diseases, the leading cause of morbidity, mortality and disability in western countries. Mounting data suggest that cardiovascular structure and function change with time as result of an "aging process", regarded as an independent process which accompanies aging, interwines and modulates superimposed traditional cardiovascular risk factors to determine the peculiar occurrence, presentations and prognosis of heart disease in the elderly. A whole body of data underlies the impairment of endothelial function due to oxidative stress as a crucial feature of the aging process acting on the cardiovascular system. Insights into molecular and cellular mechanisms of age-associated endothelial dysfunction may provide new strategies to treat age-related cardiovascular diseases.

Find related publications in this database (using NLM MeSH Indexing)

Aging - administration & dosage

Cardiovascular Diseases - etiology

Endothelium, Vascular - physiopathology

Humans - administration & dosage

Oxidative Stress - administration & dosage

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