Selected Publication:

SHR Neuro Cancer Cardio Lipid Metab Microb

Hecker, A; Schellnegger, M; Hofmann, E; Luze, H; Nischwitz, SP; Kamolz, LP; Kotzbeck, P.
The impact of resveratrol on skin wound healing, scarring, and aging.
Int Wound J. 2022; 19(1):9-28 Doi: 10.1111/iwj.13601 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Leading authors Med Uni Graz

Hecker Andrzej Stanislaw

Kotzbeck Petra

Co-authors Med Uni Graz

Hofmann Elisabeth

Kamolz Lars-Peter

Luze Hanna

Nischwitz Sebastian

Schellnegger Marlies

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Abstract:

Resveratrol is a well-known antioxidant that harbours many health beneficial properties. Multiple studies associated the antioxidant, anti-inflammatory, and cell protective effects of resveratrol. These diverse effects of resveratrol are also potentially involved in cutaneous wound healing, scarring, and (photo-)aging of the skin. Hence, this review highlighted the most relevant studies involving resveratrol in wound healing, scarring, and photo-aging of the skin. A systematic review was performed and the database PubMed was searched for suitable publications. Only original articles in English that investigated the effects of resveratrol in wound healing, scarring, and (photo-)aging of the skin were analysed. The literature search yielded a total of 826 studies, but only 41 studies met the inclusion criteria. The included studies showed promising results that resveratrol might be a feasible treatment approach to support wound healing, counteract excessive scarring, and even prevent photo-aging of the skin. Resveratrol represents an interesting and promising novel therapy regime but to confirm resveratrol-associated effects, more evidence based in vitro and in vivo studies are needed.

Find related publications in this database (using NLM MeSH Indexing)

Cicatrix - drug therapy

Humans - administration & dosage

Research Design - administration & dosage

Resveratrol - therapeutic use

Find related publications in this database (Keywords)

chronic wound

resveratrol

scarring

skin aging

wound healing

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