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SHR Neuro Cancer Cardio Lipid Metab Microb

Kron, S; Schneditz, D; Keane, DF; Leimbach, T; Kron, J.
An improved method to estimate absolute blood volume based on dialysate dilution.
Artif Organs. 2021; 45(9):E359-E363 Doi: 10.1111/aor.13970
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Co-authors Med Uni Graz

Schneditz Daniel

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Abstract:

Online hemodiafiltration machines equipped with a blood volume monitor and the possibility to rapidly infuse exact amounts of ultrapure dialysate into the extracorporeal circulation can be used to determine absolute blood volume in clinical practice. The aim of the present study was to evaluate the reproducibility of such measurements. Intra-individual reproducibility was evaluated in four measurements taken in hourly intervals within the same dialysis treatment. Ten patients were studied. Absolute blood volumes measured at the beginning and after 1 hour of dialysis were significantly different (80.6 ± 14.5 and 63.9 ± 14.3 mL/kg, P < .001) and highly reproducible between the last three measurements (63.9 ± 14.3, 61.4 ± 13.8, and 60.9 ± 13.9 mL/kg, P = n.s.). Measurement of absolute blood volume after 1 hour of treatment is more precise than earlier measurements and might be better suited for guidance of ultrafiltration.

Find related publications in this database (Keywords)

absolute blood volume

blood volume monitoring

chronic hemodialysis

dialysate dilution

volume management

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