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Liquid Biopsies for early Detection of Cancer - Modul 1 Investigation of size distribution, origin and dynamics of plasma DNA

Project Leader:

Heitzer Ellen

Duration:

01.10.2017-30.09.2024

Programme:

Christian Doppler Labor

Type of Research

applied research

Staff

Heitzer, Ellen, Project Leader

MUG Research Units

Diagnostic and Research Institute of Human Genetics

Funded by

Christian Doppler Forschungsgesellschaft (CDG), Sensengasse 1, 1090 Wien, Austria

Project results published

> Sensitive and robust liquid biopsy-based detection... Br J Cancer. 2022; 126(3):456-463

> Profiling of circulating tumor DNA and tumor tissu... Ther Adv Med Oncol. 2021; 13:1758835920987658

> Longitudinal tumor fraction trajectories predict r... Mol Oncol. 2021; 15(9):2390-2400

> Dynamic Changes of Circulating Tumor DNA Predict C... JCO PRECIS ONCOL. 2021; 5: 1540-1553.

> Technical Evaluation of Commercial Mutation Analys... Cancers (Basel). 2020; 12(6): 1588

> Cell-Free DNA and Apoptosis: How Dead Cells Inform... Trends Mol Med. 2020; 26(5):519-528

> Cell-free DNA analysis reveals POLR1D-mediated res... Genome Med. 2020; 12(1):20

> On-treatment measurements of circulating tumor DNA... NPJ Precis Oncol. 2020; 4(1):30

> Comparison of three commercial decision support pl... ESMO Open. 2020; 5(5):e000872

> Assessment of Pre-Analytical Sample Handling Condi... J Mol Diagn. 2020; 22(8):1070-1086

> Untargeted Assessment of Tumor Fractions in Plasma... Cancers (Basel). 2019; 11(8):

> One size does not fit all: Size-based plasma DNA d... SCI TRANSL MED. 2018; 10(466): eaav3873