Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
SHR
Neuro
Krebs
Kardio
Stoffw
Microb
Lipid
EMBIC: The Control of Embryo Implantation
- Abstract
- We aim to build an European virtual laboratory on major mechanism of implantation by thoroughly exploring what knock out mice have recently established as cellular - cytokine networks/ key pathways promoting the development of 2 de novo organs: the decidua basalis and the mature placenta. At present, fragmentation of experimental capacity and disparate approaches result in lack of a comprehensive skills base, and lack of access to very specialised approaches and technological platforms such as animal experimentation in very strict conditions, genomics and proteomics facilities or multicentric clinical evaluation. These require to be used in a coordinated fashion to maximise their effect in this area.
We will thus: 1.) Assemble critical talents and approaches, to develop an integrative, evaluative, capacity to set up EMBIC; 2.) Integrate EMBIC laboratories using crucial models and coordination of the joint programme of activities; 3.) Constitute a European cohort of infertile women with creation of RT generated DNA, sera and micro-biopsy tissue samples banks; 4.) Establish guidelines for management of infertile women combined with diagnosis procedures and ultimately recombinant technologies therapies for selected pathologies; 5.) Open the network of validated platforms for education and cooperative experimentation.
EMBIC will contribute and benefit from the creation of integrated platforms based on animal models, genomic and proteomic facilities, protein intra-net database set-up, integrated clinical set-up. EMBIC will spread excellence by facilitaing the exchange of scientists within the laboratories, promote recruitment/training of out network post-docs, organise workshops and satellite meetings in pan European or regional Immunology/Fertility meetings and an annual summer school.
- Lokale Teilprojektleitung:
- Sedlmayr Peter
- Laufzeit:
- 01.10.2004-30.09.2008
- Programm:
- EU (FP-6)
- EU-Projektinstrument
- Network of Excellence (NoE)
- Art der Forschung
- Grundlagenforschung
- Mitarbeiter*innen
- Sedlmayr, Peter, Projektleiter*in
- Helige, Christine, Projektmitarbeiter*in
- Daxboeck, Christine, Projektmitarbeiter*in
- Blaschitz, Astrid, Projektmitarbeiter*in
- Schmied, Rudolf, Projektmitarbeiter*in
- Walcher, Wolfgang, Projektmitarbeiter*in
- Dohr, Gottfried, Projektmitarbeiter*in
- Hutter, Heinz, Projektmitarbeiter*in
- Hammer, Astrid, Projektmitarbeiter*in
- Lang-Olip, Ingrid, Projektmitarbeiter*in
- Juch, Herbert, Projektmitarbeiter*in
- Beteiligte MUG-Organisationseinheiten
- Lehrstuhl für Zellbiologie, Histologie und Embryologie
- Universitätsklinik für Frauenheilkunde und Geburtshilfe
- Projektpartner
-
INRA, Frankreich
Kontaktperson: Lean-Paul Renard; -
INSERM, Frankreich
Kontaktperson: Gèrard Chaouat; -
Inserm-Transfert, Frankreich
Kontaktperson: Emmanuelle Benhamou; -
Istituto di Ricerche Farmacologiche "Mario Negri", Italien
Kontaktperson: Alberto Mantovani; -
Universidad autonoma de Barcelona, Großbritannien
Kontaktperson: Paz Martinez; -
Universität Friedrich Schiller Jena, Deutschland
Kontaktperson: Udo Markert; -
Universität Humboldt, Deutschland
Kontaktperson: Petra Arck; -
Université de Bordeaux, Frankreich
Kontaktperson: Jean-Francois Moreau; -
Université de Liege, Belgien
Kontaktperson: Jean-Michel Foidart; -
University of Florence, Italien
Kontaktperson: Marie-Pierre Piccinni; -
University of Oxford, Großbritannien
Kontaktperson: Ian Sargent; -
University of Pecs, Ungarn
Kontaktperson: Julia Szekeres Bartho; -
University of Rijeka, Kroatien
Kontaktperson: Daniel Rukavina; -
University of Rome "La Sapienza", Italien
Kontaktperson: Angela Santoni; -
University of Trieste, Italien
Kontaktperson: Francesco Tedesco; -
University of Warwick, Großbritannien
Kontaktperson: Colin Ockleford;
- Gefördert durch
- Europäische Kommission, Rue de la Loi, Brussels, Belgien
- Publizierte Projektergebnisse
- > Neuroendocrine circuitry and endometriosis: proges... J Mol Med. 2010; 88(3): 267-278.
- > Role of indoleamine 2,3-dioxygenase in materno-fet... XVIth Symposium of Czech Reproductive Immunologists with International Participation; MAY 28-30, 2010; Zdar nad Sazavou, CZECH REPUBLIC. 2010.
- > A new method of morphometric analysis of tissue ti... International Immunology 2010; 22 suppl. 1: ii65-ii65.-14th International Congress of Immunology; AUG 22-27; Kobe, JAPAN.
- > Measurement of cell death by oxidative stress in t... J REPROD IMMUNOL. 2010; 85(1): 63-70.
- > Morphometric analysis: applications in placenta im... Abstracts of the 7th European Congress on Reproductive Immunology2009; 81(2):126-126.-7th European Congress on Reproductive Immunology; Sept. 17-20, 2009; Marathon, GREECE.
- > Progesterone-induced blocking factor is expressed ... Am. J. Reprod. Immunol.2007; 58(3):223-223.-5th European Congress of Reproductive Immunology; AUG 30 - SEPT 2, 2007; Berlin, GERMANY.