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Characterization of the pro-apoptotic action of the alpha1-adrenergic antagonist prazosin on malignant cells.

Project Leader:

Fuchs Robert

Duration:

01.07.2011-01.07.2012

Type of Research

basic research

Staff

Fuchs, Robert, Project Leader

MUG Research Units

Division of Immunology

Funded by

Franz-Lanyar-Stiftung, Graz, Austria

Project results published

> Prazosin induced lysosomal tubulation interferes w... Biochim Biophys Acta Mol Cell Res. 2018; 1865(9):1211-1229

> The anti-hypertensive drug prazosin induces apopto... Anticancer Res. 2015; 35(1):31-38

> The cytotoxicity of the α1-adrenoceptor antagonist... Toxicology. 2015; 338(6):17-29

> The proapoptotic drug Prazosin enters cancer cells... Guide & Abstract Book International Student Congress 2014. 2014; -International Student Congress 2014; JUL 10-12, 2014; Graz, AUSTRIA. (ISBN: 978-3-200-03683-3 )

> Prazosin induces apoptosis in Medullary Thyroid Ca... European Thyroid Journal; 36 Annual Meeting of the European Thyroid Association, Programme and Abstracts. 2012; 1(S1):1-208.-36th Annual Meeting of the ETA; SEPT 8-12, 2012; Pisa, ITALY. (ISBN: 978-3-318-0222 )

> Quinazoline sensitive binding sites are promising ... 13th International Workshop on Multiple Endocrine Neoplasia; SEPT 5-8, 2012; Liege, BELGIUM. 2012.

> Identification of Quinazoline sensitive binding si... 4th ÖGMBT ANNUAL MEETING; SEPT 17-19, 2012; Graz, AUSTRIA. 2012.