Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Abstract: The increasing incidence of cancer and of degenerative diseases, the latter uncreasingly in relatively young patients, calls for a new healthcare model that is more proactive (detects asymptomatic disease when it is more amenable to treatment), more personalised (based on the growing knowledge about the molecular mechanisms underlying disease), less traumatic and more targeted (non/minimally invasively and specifically treats the affected tissue or organ(s)) and that allows more informed interventions (following of the progress of therapy and disease reoccurrence in as close to real time as possible).
This prolongation of NANO-HEALTH will build on the work done to date to develop new NM-based solutions for targeted drug delivery and imaging. The following topics will be pursued:
*Further development of thiomers for oral delivery of active substances
*An industrial production process for nano-thiomers
*Development of targeted imaging for cancer using MRI
*Stem cell tracking in vivo
*Atherosclerotic plaque detection
*Chronic nanotoxicity

Projektpartner: Austrian Academy of Sciences, Österreich; Green River Polymers Forschungs- und Entwicklungs- GmbH, Österreich; Guerbet, Frankreich; Karl-Franzens-Universität Graz, Österreich; Medizinische Universität Innsbruck (MUI), Österreich; Medizinische Universität Wien (MUW), Österreich; piCHEM Forschungs- und Entwicklungs GmbH, Österreich; RCPE GmbH- Research Center of Pharmaceutical Engineering, Österreich; Siemens AG Österreich, Österreich; Technische Universität Graz, Österreich; Thiomatrix Forschungs- und Entwicklungs GmbH, Österreich; Universität Innsbruck, Österreich

Gefördert durch: Österreichische Forschungsförderungsgesellschaft mbH (FFG/mit peer review), Sensengasse 1, 1090 Wien, Österreich