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Höfler Gerald |

** = Publications listed in SCI/SSCI/Pubmed

2025

Full paper/article (Journal)

** Grechenig, P; Hallmann, B; Eibinger, N; Koutp, A; Schroedter, R; Höfler, G; Puchwein, P Evaluation of the implementation of the minimally invasive emergency procedure REBOA via an open surgical approach in a teaching unit - a cadaveric study.
Arch Orthop Trauma Surg. 2025; 145(1): 200 Doi: 10.1007/s00402-025-05786-z
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** Peña, de, la, Sancha, P; Wieser, BI; Schauer, S; Reicher, H; Sattler, W; Breinbauer, R; Schweiger, M; Lechleitner, M; Frank, S; Zechner, R; Kratky, D; Espenshade, PJ; Hoefler, G; Vesely, PW Lipolysis-derived fatty acids are needed for homeostatic control of sterol element-binding protein-1c driven hepatic lipogenesis.
Commun Biol. 2025; 8(1):588 Doi: 10.1038/s42003-025-08002-1 [OPEN ACCESS]
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2024

Full paper/article (Journal)

** Babalola, JA; Stracke, A; Loeffler, T; Schilcher, I; Sideromenos, S; Flunkert, S; Neddens, J; Lignell, A; Prokesch, M; Pazenboeck, U; Strobl, H; Tadic, J; Leitinger, G; Lass, A; Hutter-Paier, B; Hoefler, G Effect of astaxanthin in type-2 diabetes -induced APPxhQC transgenic and NTG mice.
Mol Metab. 2024; 85:101959 Doi: 10.1016/j.molmet.2024.101959 [OPEN ACCESS]
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** Chrysostomou, SE; Eder, S; Pototschnig, I; Mayer, AL; Derler, M; Mussbacher, M; Schauer, S; Zhang, DX; Yan, DM; Liu, GN; Hoefler, G; Weichhart, T; Vesely, PW; Zhang, LB; Schweiger, M R-ketorolac ameliorates cancer-associated cachexia and prolongs survival of tumour-bearing mice
J CACHEXIA SARCOPENI. 2024; Doi: 10.1002/jcsm.13422 [OPEN ACCESS]
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** Grechenig, P; Hallmann, B; Eibinger, NR; Koutp, A; Zajic, P; Höfler, G; Puchwein, P Percutaneous ultrasound-guided versus open cut-down access to femoral vessels for the placement of a REBOA catheter.
Sci Rep. 2024; 14(1): 9111 Doi: 10.1038/s41598-024-59778-x [OPEN ACCESS]
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** Skok, K; Zacharias, M; Verheyen, N; Hatzl, S; Scholz, L; Langner, C; Hoefler, G; Vagena, FR Myeloid sarcoma of the heart-A clinicopathological correlation.
Wien Klin Wochenschr. 2024; Doi: 10.1007/s00508-024-02478-3 [OPEN ACCESS]
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** Tehlivets, O; Almer, G; Brunner, MS; Lechleitner, M; Sommer, G; Kolb, D; Leitinger, G; Diwoky, C; Wolinski, H; Habisch, H; Opriessnig, P; Bogoni, F; Pernitsch, D; Kavertseva, M; Bourgeois, B; Kukilo, J; Tehlivets, YG; Schwarz, AN; Züllig, T; Bubalo, V; Schauer, S; Groselj-Strele, A; Hoefler, G; Rechberger, GN; Herrmann, M; Eller, K; Rosenkranz, AR; Madl, T; Frank, S; Holzapfel, GA; Kratky, D; Mangge, H; Hörl, G Homocysteine contributes to atherogenic transformation of the aorta in rabbits in the absence of hypercholesterolemia.
BIOMED PHARMACOTHER. 2024; 178: 117244 Doi: 10.1016/j.biopha.2024.117244
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** Wurm, S; Waltersdorfer, M; Loindl, S; Moritz, JM; Herzog, SA; Bachmaier, G; Berghold, A; Kashofer, K; Beham-Schmid, C; Hoefler, G; Greinix, HT; Wölfler, A; Reinisch, A; Sill, H; Zebisch, A Acute myeloid leukemia in the next-generation sequencing era : Real-world data from an Austrian tertiary cancer care center.
Wien Klin Wochenschr. 2024; Doi: 10.1007/s00508-024-02463-w
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Review

** Ilié, M; Lake, V; de, Alava, E; Bonin, S; Chlebowski, S; Delort, A; Dequeker, E; Al-Dieri, R; Diepstra, A; Carpén, O; Eloy, C; Fassina, A; Fend, F; Fernandez, PL; Gorkiewicz, G; Heeke, S; Henrique, R; Hoefler, G; Huertas, P; Hummel, M; Kashofer, K; van, der, Laak, J; de, Pablos, RM; Schmitt, F; Schuuring, E; Stanta, G; Timens, W; Westphalen, B; Hofman, P Standardization through education of molecular pathology: a spotlight on the European Masters in Molecular Pathology.
Virchows Arch. 2024; 485(5):761-775 Doi: 10.1007/s00428-024-03933-2
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** Matias-Guiu, X; Hoefler, G Editorial: Molecular pathology as basis for timely cancer diagnosis and therapy
VIRCHOWS ARCH. 2024; 484(2): 151-154. Doi: 10.1007/s00428-024-03767-y
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Correction

** Babalola, JA; Stracke, A; Loeffler, T; Schilcher, I; Sideromenos, S; Flunkert, S; Neddens, J; Lignell, A; Prokesch, M; Panzenboeck, U; Strobl, H; Tadic, J; Leitinger, G; Lass, A; Hutter-Paier, B; Hoefler, G Corrigendum to "Effect of astaxanthin in type-2 diabetes -induced APPxhQC transgenic and NTG mice" [MOLMET 85 (2024) 1-16].
Mol Metab. 2024; 86:101972 Doi: 10.1016/j.molmet.2024.101972 [OPEN ACCESS]
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Abstract (Journal)

** Moik, F; Riedl, JM; Edlinger, L; Esterl, T; Hasenleithner, S; Kostmann, S; Cebular, L; Jahn, S; Kashofer, K; Zacharias, M; Hoefler, G; Heitzer, E; Gerger, A; Jost, PJ Practice patterns and treatment outcomes of molecular tumour board (MTB)-based personalized cancer therapies: A single-center experience
ANN ONCOL. 2024; 35: S262-S263. Doi: 10.1016/j.annonc.2024.08.130
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** Vesely, PW; Thanh, HPT; Kanti, M; Subramaniyan, B; Moore, A; Georgescu, C; Wren, JD; Freeman, WM; Syarif, AH; Schauer, S; Schweiger, M; Kwapiszewska, G; Hoefler, G; Walters, MS; Marsh, LM Lipid-signaling as a Potential New Therapeutic Target in Chronic Obstructive Pulmonary Disease
AM J RESP CRIT CARE. 2024; 209: -ATS International Conference; MAY 17-22, 2024; San Diego, USA. [Oral Communication]
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2023

Full paper/article (Journal)

** Amor, M; Bianco, V; Buerger, M; Lechleitner, M; Vujić, N; Dobrijević, A; Akhmetshina, A; Pirchheim, A; Schwarz, B; Pessentheiner, AR; Baumgartner, F; Rampitsch, K; Schauer, S; Klobučar, I; Degoricija, V; Pregartner, G; Kummer, D; Svecla, M; Sommer, G; Kolb, D; Holzapfel, GA; Hoefler, G; Frank, S; Norata, GD; Kratky, D Genetic deletion of MMP12 ameliorates cardiometabolic disease by improving insulin sensitivity, systemic inflammation, and atherosclerotic features in mice.
Cardiovasc Diabetol. 2023; 22(1): 327 Doi: 10.1186/s12933-023-02064-3 [OPEN ACCESS]
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** Babalola, JA; Lang, MGLA; George, M; Stracke, A; Tam-Amersdorfer, C; Itxaso, I; Lucija, D; Tadic, J; Schilcher, I; Loeffler, T; Flunkert, S; Prokesch, M; Leitinger, G; Lass, A; Hutter-Paier, B; Panzenboeck, U; Hoefler, G Astaxanthin enhances autophagy, amyloid beta clearance and exerts anti-inflammatory effects in in vitro models of Alzheimer's disease-related blood brain barrier dysfunction and inflammation
BRAIN RES. 2023; 1819: 148518 Doi: 10.1016/j.brainres.2023.148518
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** Bianco, V; Korbelius, M; Vujic, N; Akhmetshina, A; Amor, M; Kolb, D; Pirchheim, A; Bradic, I; Kuentzel, KB; Buerger, M; Schauer, S; Phan, HTT; Bulfon, D; Hoefler, G; Zimmermann, R; Kratky, D Impact of (intestinal) LAL deficiency on lipid metabolism and macrophage infiltration.
Mol Metab. 2023; 73: 101737 Doi: 10.1016/j.molmet.2023.101737 [OPEN ACCESS]
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** Hardy, SA; Liesinger, L; Patrick, R; Poettler, M; Rech, L; Gindlhuber, J; Mabotuwana, NS; Ashour, D; Stangl, V; Bigland, M; Murtha, LA; Starkey, MR; Scherr, D; Hansbro, PM; Hoefler, G; Campos, Ramos, G; Cochain, C; Harvey, RP; Birner-Gruenberger, R; Boyle, AJ; Rainer, PP Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction.
JACC Basic Transl Sci. 2023; 8(12): 1539-1554. Doi: 10.1016/j.jacbts.2023.05.010 [OPEN ACCESS]
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** Jørgensen, SM; Lorentzen, LG; Hammer, A; Hoefler, G; Malle, E; Chuang, CY; Davies, MJ The inflammatory oxidant peroxynitrous acid modulates the structure and function of the recombinant human V3 isoform of the extracellular matrix proteoglycan versican.
Redox Biol. 2023; 64: 102794 Doi: 10.1016/j.redox.2023.102794 [OPEN ACCESS]
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** Kolleritsch, S; Pajed, L; Tilp, A; Hois, V; Pototschnig, I; Kien, B; Diwoky, C; Hoefler, G; Schoiswohl, G; Haemmerle, G Adverse cardiac remodeling augments adipose tissue ss-adrenergic signaling and lipolysis counteracting diet-induced obesity
J BIOL CHEM. 2023; 299(6): 104788 Doi: 10.1016/j.jbc.2023.104788 [OPEN ACCESS]
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** Pöltl, L; Kitsera, M; Raffl, S; Schild, S; Cosic, A; Kienesberger, S; Unterhauser, K; Raber, G; Lembacher-Fadum, C; Breinbauer, R; Gorkiewicz, G; Sebastian, C; Hoefler, G; Zechner, EL Microbiota-derived genotoxin tilimycin generates colonic stem cell mutations.
Cell Rep. 2023; 42(3):112199 Doi: 10.1016/j.celrep.2023.112199
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** Pototschnig, I; Feiler, U; Diwoky, C; Vesely, PW; Rauchenwald, T; Paar, M; Bakiri, L; Pajed, L; Hofer, P; Kashofer, K; Sukhbaatar, N; Schoiswohl, G; Weichhart, T; Hoefler, G; Bock, C; Pichler, M; Wagner, EF; Zechner, R; Schweiger, M Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia.
J Cachexia Sarcopenia Muscle. 2023; 14(1):93-107 Doi: 10.1002/jcsm.13109 [OPEN ACCESS]
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** Richtig, G; Kienzl, M; Rittchen, S; Roula, D; Eberle, J; Sarif, Z; Pichler, M; Hoefler, G; Heinemann, A Cannabinoids Reduce Melanoma Cell Viability and Do Not Interfere with Commonly Used Targeted Therapy in Metastatic Melanoma In Vivo and In Vitro.
BIOLOGY-BASEL. 2023; 12(5): Doi: 10.3390/biology12050706 [OPEN ACCESS]
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** Sconocchia, T; Foßelteder, J; Auinger, L; Özkaya, E; Benezeder, T; Lang, M; Beham-Schmid, C; Hoefler, G; Zebisch, A; Wölfler, A; Sill, H; Wolf, P; Strobl, H; Reinisch, A BRAF^V600E promotes DC3/monocyte differentiation in human gene-engineered HSPCs and causes multisystem histiocytosis.
Leukemia. 2023; 37(11): 2292-2296. Doi: 10.1038/s41375-023-02019-3 [OPEN ACCESS]
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** Wang, YH; Hammer, A; Hoefler, G; Malle, E; Hawkins, CL; Chuang, CY; Davies, MJ Hypochlorous Acid and Chloramines Induce Specific Fragmentation and Cross-Linking of the G1-IGD-G2 Domains of Recombinant Human Aggrecan, and Inhibit ADAMTS1 Activity
ANTIOXIDANTS-BASEL. 2023; 12(2): 420 Doi: 10.3390/antiox12020420 [OPEN ACCESS]
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Editorial

** Seidel, MG; Brcic, L; Hoefler, G; Hutter, C; Minkov, M; Steffen, LS; Zebisch, A; Benesch, M Concurrence of a kinase-dead BRAF and an oncogenic KRAS gain-of-function mutation in juvenile xanthogranuloma.
Pediatr Blood Cancer. 2023; 70(4):e30060 Doi: 10.1002/pbc.30060
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Abstract (Journal)

** Benedikt, M; Kolesnik, E; Wallner, M; Hofler, G; Stangl, VM; Zirlik, A; Rainer, P Giant cell myocarditis manifesting as severe heart failure with cardiogenic shock
WIEN KLIN WOCHENSCHR. Abstracts. 2023; 135(S2):S342-S343.-ÖKG Jahrestagung; MAY 31-JUN 3, 2023; Salzburg, AUSTRIA. [Oral Communication]
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** Hardy, SS; Patrick, R; Liesinger, L; Gindlehuber, J; Pottler, M; Rech, L; Mabotuwana, N; Stagl, V; Ashour, D; Hofler, G; Cochain, C; Harvey, R; Birner-Gruenberger, R; Boyle, A; Rainer, P Extracellular matrix protein 1 as a novel mediator of inflammation-to-fibrosis progression after myocardial infarction
EUR J HEART FAIL. Abstracts. 2023; 25(S1):14-14.-HFA Winter Research Meeting on Translational Heart Failure; MAY 20-23, 2023; Prague, CZECH REPUBLIC. [Oral Communication]
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** Riedl, JM; Steinlechner, SM; Moik, F; Heitzer, E; Jahn, S; Hasenleithner, S; Doleschal, B; Weiss, L; Seeber, A; Rumpold, H; Winder, T; Greil, R; Jost, PJ; Hoefler, G; Speicher, M; Gerger, A SOUND: A phase II trial evaluating the efficacy of molecular profiling of circulating ± tumor tissue DNA for salvagetherapy matching in patients with advanced and refractory carcinoma
ANN ONCOL. 2023; 34: S1186-S1186.-Annual Meeting of the European-Society-for-Medical-Oncology (ESMO); OCT 20-24, 2023; Barcelona, SPAIN. Doi: 10.1016/j.annonc.2023.09.1349 [Poster]
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2022

Full paper/article (Journal)

** Almer, G; Opriessnig, P; Wolinski, H; Sommer, G; Diwoky, C; Lechleitner, M; Kolb, D; Bubalo, V; Brunner, MS; Schwarz, AN; Leitinger, G; Schoiswohl, G; Marsche, G; Niedrist, T; Schauer, S; Oswald, W; Groselj-Strele, A; Paar, M; Cvirn, G; Hoefler, G; Rechberger, GN; Herrmann, M; Frank, S; Holzapfel, GA; Kratky, D; Mangge, H; Hörl, G; Tehlivets, O Deficiency of B vitamins leads to cholesterol-independent atherogenic transformation of the aorta.
Biomed Pharmacother. 2022; 154:113640 Doi: 10.1016/j.biopha.2022.113640 [OPEN ACCESS]
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** Kanti, MM; Striessnig-Bina, I; Wieser, BI; Schauer, S; Leitinger, G; Eichmann, TO; Schweiger, M; Winkler, M; Winter, E; Lana, A; Kufferath, I; Marsh, LM; Kwapiszewska, G; Zechner, R; Hoefler, G; Vesely, PW Adipose triglyceride lipase-mediated lipid catabolism is essential for bronchiolar regeneration.
JCI Insight. 2022; 7(9): Doi: 10.1172/jci.insight.149438 [OPEN ACCESS]
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** Koyani, CN; Scheruebel, S; Jin, G; Kolesnik, E; Zorn-Pauly, K; Mächler, H; Hoefler, G; von, Lewinski, D; Heinzel, FR; Pelzmann, B; Malle, E Hypochlorite-Modified LDL Induces Arrhythmia and Contractile Dysfunction in Cardiomyocytes.
Antioxidants (Basel). 2021; 11(1): Doi: 10.3390/antiox11010025 [OPEN ACCESS]
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** Xie, H; Heier, C; Meng, X; Bakiri, L; Pototschnig, I; Tang, Z; Schauer, S; Baumgartner, VJ; Grabner, GF; Schabbauer, G; Wolinski, H; Robertson, GR; Hoefler, G; Zeng, W; Wagner, EF; Schweiger, M; Zechner, R An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia.
Proc Natl Acad Sci U S A. 2022; 119(9): Doi: 10.1073/pnas.2112840119 [OPEN ACCESS]
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2021

Full paper/article (Journal)

** Berg, JL; Perfler, B; Hatzl, S; Mayer, MC; Wurm, S; Uhl, B; Reinisch, A; Klymiuk, I; Tierling, S; Pregartner, G; Bachmaier, G; Berghold, A; Geissler, K; Pichler, M; Hoefler, G; Strobl, H; Wölfler, A; Sill, H; Zebisch, A Micro-RNA-125a mediates the effects of hypomethylating agents in chronic myelomonocytic leukemia.
Clin Epigenetics. 2021; 13(1): 1-1. Doi: 10.1186/s13148-020-00979-2 [OPEN ACCESS]
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** Berg, JL; Perfler, B; Hatzl, S; Uhl, B; Reinisch, A; Pregartner, G; Berghold, A; Penz, T; Schuster, M; Geissler, K; Prokesch, A; Müller-Tidow, C; Hoefler, G; Kashofer, K; Wölfler, A; Sill, H; Caraffini, V; Zebisch, A EZH2 inactivation in RAS-driven myeloid neoplasms hyperactivates RAS-signaling and increases MEK inhibitor sensitivity.
Leukemia. 2021; 35(5):1521-1526 Doi: 10.1038/s41375-021-01161-0 [OPEN ACCESS]
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** Jin, G; Manninger, M; Adelsmayr, G; Schwarzl, M; Alogna, A; Schönleitner, P; Zweiker, D; Blaschke, F; Sherif, M; Radulovic, S; Wakula, P; Schauer, S; Höfler, G; Reiter, U; Reiter, G; Post, H; Scherr, D; Acsai, K; Antoons, G; Pieske, B; Heinzel, FR Cellular contribution to left and right atrial dysfunction in chronic arterial hypertension in pigs.
ESC Heart Fail. 2021; 8(1):151-161 Doi: 10.1002/ehf2.13087 [OPEN ACCESS]
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** Larose, H; Prokoph, N; Matthews, JD; Schlederer, M; Högler, S; Alsulami, AF; Ducray, SP; Nuglozeh, E; Fazaludeen, FMS; Elmouna, A; Ceccon, M; Mologni, L; Gambacorti-Passerini, C; Hoefler, G; Lobello, C; Pospisilova, S; Janikova, A; Woessmann, W; Damm-Welk, C; Zimmermann, M; Federova, A; Malone, A; Smith, O; Wasik, M; Inghirami, G; Lamant, L; Blundell, TL; Klapper, W; Merkel, O; Burke, AGA; Mian, S; Ashankyty, I; Kenner, L; Turner, SD Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target.
HAEMATOLOGICA. 2021; 106(6): 1693-1704. Doi: 10.3324/haematol.2019.238766 [OPEN ACCESS]
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** Pajed, L; Taschler, U; Tilp, A; Hofer, P; Kotzbeck, P; Kolleritsch, S; Radner, FPW; Pototschnig, I; Wagner, C; Schratter, M; Eder, S; Huetter, S; Schreiber, R; Haemmerle, G; Eichmann, TO; Schweiger, M; Hoefler, G; Kershaw, EE; Lass, A; Schoiswohl, G Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase.
Commun Biol. 2021; 4(1):323 Doi: 10.1038/s42003-021-01858-z [OPEN ACCESS]
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** Riedl, JM; Hasenleithner, SO; Pregartner, G; Scheipner, L; Posch, F; Groller, K; Kashofer, K; Jahn, SW; Bauernhofer, T; Pichler, M; Stöger, H; Berghold, A; Hoefler, G; Speicher, MR; Heitzer, E; Gerger, A Profiling of circulating tumor DNA and tumor tissue for treatment selection in patients with advanced and refractory carcinoma: a prospective, two-stage phase II Individualized Cancer Treatment trial.
Ther Adv Med Oncol. 2021; 13:1758835920987658 Doi: 10.1177/1758835920987658 [OPEN ACCESS]
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Short report/Letter

** Robier, C; Hoefler, G; Egger, M Simultaneous occurrence of EDTA-dependent lymphoagglutination and agglutination of myeloid cells in a patient with chronic myelomonocytic leukemia.
CLIN CHEM LAB MED. 2021; 59(12): e458-e460. Doi: 10.1515/cclm-2021-0616
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Case Report

** Robier, C; Hoefler, G; Aubell, K; Hubmann, E Acquired elliptocytosis as presenting sign of a myelodysplastic syndrome associated with deletion of chromosome 20 and mutations in TET2, DNMT3A, and U2AF1.
Ann Hematol. 2021; 100(8):2111-2112 Doi: 10.1007/s00277-020-04368-w (- Case Report)
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Abstract (Journal)

** Almer, G; Brunner, M; Schwarz, A; Diwoky, C; Lechleitner, M; Sommer, G; Kolb, D; Wolinski, H; Oswald, WK; Opriessnig, P; Horl, G; Groselj-Strele, A; Hofler, G; Rechberger, GN; Frank, S; Holzapfel, GA; Kratky, D; Mangge, H; Tehlivets, O Hypercholesterolemia “masks” defects in homocysteine degradation in a rabbit model of atherosclerosis
ATHEROSCLEROSIS. 2021; 331: E208-E208.-Austrian Atherosclerosis Society ONLINE-KONGRESS; 07.05.2021; [Oral Communication]
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Abstract (Proceedings)

** Babalola, JA; Lang, M; George, M; Stracke, A; Tadic, J; Madeo, F; Lass, A; Leitinger, G; Hutter-Paier, B; Hoefler, G; Panzenboeck, U Astaxanthin enhances LRP1-modulated insulin sensitivity and amyloid beta clearance in an in vitro blood-brain barrier model.
Alzheimers Dement. AAIC 2021 Abstracts. 2021; 17 Suppl 3: e053736--Alzheimer’s Association International Conference, AAIC 2021; JULY 26-30, 2021; Denver, USA. Doi: 10.1002/alz.053736 [Poster]
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2020

Full paper/article (Journal)

** Alkan, HF; Vesely, PW; Hackl, H; Foßelteder, J; Schmidt, DR; Vander Heiden, MG; Pichler, M; Hoefler, G; Bogner-Strauss, JG Deficiency of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis.
Cancer Metab. 2020; 8(1):26-26 Doi: 10.1186/s40170-020-00232-7 [OPEN ACCESS]
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** Caraffini, V; Geiger, O; Rosenberger, A; Hatzl, S; Perfler, B; Berg, JL; Lim, C; Strobl, H; Kashofer, K; Schauer, S; Beham-Schmid, C; Hoefler, G; Geissler, K; Quehenberger, F; Kolch, W; Athineos, D; Blyth, K; Wölfler, A; Sill, H; Zebisch, A Loss of RAF kinase inhibitor protein is involved in myelomonocytic differentiation and aggravates RAS-driven myeloid leukemogenesis.
Haematologica. 2020; 105(2):375-386 Doi: 10.3324/haematol.2018.209650 [OPEN ACCESS]
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** Daga, S; Rosenberger, A; Kashofer, K; Heitzer, E; Quehenberger, F; Halbwedl, I; Graf, R; Krisper, N; Prietl, B; Höfler, G; Reinisch, A; Zebisch, A; Sill, H; Wölfler, A Sensitive and broadly applicable residual disease detection in acute myeloid leukemia using flow cytometry-based leukemic cell enrichment followed by mutational profiling.
Am J Hematol. 2020; 95(10):1148-57 Doi: 10.1002/ajh.25918 [OPEN ACCESS]
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** Karastaneva, A; Nebral, K; Schlagenhauf, A; Baschin, M; Palankar, R; Juch, H; Heitzer, E; Speicher, MR; Höfler, G; Grigorow, I; Urban, C; Benesch, M; Greinacher, A; Haas, OA; Seidel, MG Novel phenotypes observed in patients with ETV6-linked leukaemia/familial thrombocytopenia syndrome and a biallelic ARID5B risk allele as leukaemogenic cofactor.
J Med Genet. 2020; 57(6):427-433 Doi: 10.1136/jmedgenet-2019-106339
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** Kolleritsch, S; Kien, B; Schoiswohl, G; Diwoky, C; Schreiber, R; Heier, C; Maresch, LK; Schweiger, M; Eichmann, TO; Stryeck, S; Krenn, P; Tomin, T; Schittmayer, M; Kolb, D; Rülicke, T; Hoefler, G; Wolinski, H; Madl, T; Birner-Gruenberger, R; Haemmerle, G Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice.
Cardiovasc Res. 2020; 116(2):339-352 Doi: 10.1093/cvr/cvz119 [OPEN ACCESS]
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** Lord, SR; Collins, JM; Cheng, WC; Haider, S; Wigfield, S; Gaude, E; Fielding, BA; Pinnick, KE; Harjes, U; Segaran, A; Jha, P; Hoefler, G; Pollak, MN; Thompson, AM; Roy, PG; English, R; Adams, RF; Frezza, C; Buffa, FM; Karpe, F; Harris, AL Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.
Br J Cancer. 2020; 122(2):258-265 Doi: 10.1038/s41416-019-0665-5 [OPEN ACCESS]
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** Maneikyte, J; Bausys, A; Leber, B; Feldbacher, N; Hoefler, G; Kolb-Lenz, D; Strupas, K; Stiegler, P; Schemmer, P Dietary Glycine Prevents FOLFOX Chemotherapy-Induced Heart Injury: A Colorectal Cancer Liver Metastasis Treatment Model in Rats.
Nutrients. 2020; 12(9): Doi: 10.3390/nu12092634 [OPEN ACCESS]
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** Moser, T; Waldispuehl-Geigl, J; Belic, J; Weber, S; Zhou, Q; Hasenleithner, SO; Graf, R; Terzic, JA; Posch, F; Sill, H; Lax, S; Kashofer, K; Hoefler, G; Schoellnast, H; Heitzer, E; Geigl, JB; Bauernhofer, T; Speicher, MR On-treatment measurements of circulating tumor DNA during FOLFOX therapy in patients with colorectal cancer.
NPJ Precis Oncol. 2020; 4(1):30 Doi: 10.1038/s41698-020-00134-3 [OPEN ACCESS]
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** Perakis, SO; Weber, S; Zhou, Q; Graf, R; Hojas, S; Riedl, JM; Gerger, A; Dandachi, N; Balic, M; Hoefler, G; Schuuring, E; Groen, HJM; Geigl, JB; Heitzer, E; Speicher, MR Comparison of three commercial decision support platforms for matching of next-generation sequencing results with therapies in patients with cancer.
ESMO Open. 2020; 5(5):e000872 Doi: 10.1136/esmoopen-2020-000872 [OPEN ACCESS]
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** Prager, G; Gerger, A; Hofler, G; Webersinke, G; Rumpold, H; Winder, T; Bartsch, R; Preusser, M; Eisterer, W Position statement of the Austrian Society for Hematology and Medical Oncology on the use of molecular diagnostics in solid tumors.
MEMO-MAG EUR MED ONC. 2020; Doi: 10.1007/s12254-020-00662-5
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** Wimmer, K; Hulla, W; Zschocke, J; Lax, SF; Webersinke, G; Zelger, B; Uyanik, G; Kain, R; Speicher, M; Hoefler, G Detection of hereditary colon and uterine cancer Consensus of the Austrian Working Group Pathology-Human Genetics to improve the care for Lynch syndrome patients and affected relatives.
ONKOLOGE. 2020; Doi: 10.1007/s00761-020-00773-y [OPEN ACCESS]
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** Xie, H; Heier, C; Kien, B; Vesely, PW; Tang, Z; Sexl, V; Schoiswohl, G; Strießnig-Bina, I; Hoefler, G; Zechner, R; Schweiger, M Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020; 1865(9):158737-158737 Doi: 10.1016/j.bbalip.2020.158737 [OPEN ACCESS]
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** Zhou, Q; Perakis, SO; Ulz, P; Mohan, S; Riedl, JM; Talakic, E; Lax, S; Tötsch, M; Hoefler, G; Bauernhofer, T; Pichler, M; Gerger, A; Geigl, JB; Heitzer, E; Speicher, MR Cell-free DNA analysis reveals POLR1D-mediated resistance to bevacizumab in colorectal cancer.
Genome Med. 2020; 12(1):20 Doi: 10.1186/s13073-020-0719-6 [OPEN ACCESS]
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Short report/Letter

** Zebisch, A; Winter, G; Kashofer, K; Hatzl, S; Uhl, B; Wurm, S; Wölfler, A; Greinix, HT; Hoefler, G; Sill, H The role of germline mutation profiling in the selection of related donors for haematopoietic stem cell transplantation.
Bone Marrow Transplant. 2020; 55(7):1502-1505 Doi: 10.1038/s41409-019-0691-1 [OPEN ACCESS]
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Review

** Al-Zoughbi, W; Hoefler, G Tumor Macroenvironment: An Update.
Pathobiology. 2020; 87(2):58-60 Doi: 10.1159/000502097 [OPEN ACCESS]
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** Matias-Guiu, X; Stanta, G; Carneiro, F; Ryska, A; Hoefler, G; Moch, H; European Society of Pathology (ESP) The leading role of pathology in assessing the somatic molecular alterations of cancer: Position Paper of the European Society of Pathology.
Virchows Arch. 2020; 476(4):491-497 Doi: 10.1007/s00428-020-02757-0 [OPEN ACCESS]
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Abstract (Journal)

** Gerger, A; Riedl, JM; Perakis, S; Pregartner, G; Scheipner, L; Posch, F; Groller, K; Kashofer, K; Jahn, SW; Bauernhofer, T; Pichler, M; Stoger, H; Berghold, A; Hofler, G; Speicher, M; Heitzer, E Profiling of circulating tumour DNA for treatment selection in patients with advanced and refractory carcinoma: A prospective, two-stage phase II individualized cancer treatment trial.
ANN ONCOL. 2020; 31: S1095-S1096.-ESMO Virtual Congress; SEP 19-OCT 18, 2020; ELECTR NETWORK. Doi: 10.1016/j.annonc.2020.08.1331 [Onlinepräsentation] [OPEN ACCESS]
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** Moser, T; Waldispuehl-Geigl, J; Belic, J; Perakis, S; Weber, S; Zhou, Q; Sill, H; Lax, S; Kashofer, K; Hoefler, G; Schoellnast, H; Bauernhofer, T; Heitzer, E; Geigl, JB; Speicher, MR Early circulating tumor DNA dynamics as a real-time predictor of FOLFOX efficacy in advanced colorectal cancer patients
CANCER RES. 2020; 80(16): Doi: 10.1158/1538-7445.AM2020-4295 [Poster]
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** Riedl, J; Perakis, S; Pregartner, G; Scheipner, L; Posch, F; Groller, K; Kashofer, K; Jahn, SW; Bauernhofer, T; Pichler, M; Stoger, H; Berghold, A; Hofler, G; Speicher, M; Heitzer, E; Gerger, A Individualized cancer treatment based on molecular profiling of circulating tumor DNA in patients with advanced and refractory carcinoma: a prospective phase II trial.
ONCOL RES TREAT. 2020; 43(SUPPL 4):249-249.-DGHO Jahrestagung; 09.10. -11.10.2020; Basel (virtueller Kongress). [Oral Communication]
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2019

Full paper/article (Journal)

** Dufraing, K; van Krieken, JH; De Hertogh, G; Hoefler, G; Oniscu, A; Kuhlmann, TP; Weichert, W; Marchiò, C; Ristimäki, A; Ryška, A; Scoazec, JY; Dequeker, E Neoplastic cell percentage estimation in tissue samples for molecular oncology: recommendations from a modified Delphi study.
HISTOPATHOLOGY. 2019; 75(3): 312-319. Doi: 10.1111/his.13891 [OPEN ACCESS]
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** Hofer, DC; Zirkovits, G; Pelzmann, HJ; Huber, K; Pessentheiner, AR; Xia, W; Uno, K; Miyazaki, T; Kon, K; Tsuneki, H; Pendl, T; Al Zoughbi, W; Madreiter-Sokolowski, CT; Trausinger, G; Abdellatif, M; Schoiswohl, G; Schreiber, R; Eisenberg, T; Magnes, C; Sedej, S; Eckhardt, M; Sasahara, M; Sasaoka, T; Nitta, A; Hoefler, G; Graier, WF; Kratky, D; Auwerx, J; Bogner-Strauss, JG N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health.
FASEB J. 2019; 33(12):13808-13824 Doi: 10.1096/fj.201801323R [OPEN ACCESS]
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** Leopold, C; Duta-Mare, M; Sachdev, V; Goeritzer, M; Maresch, LK; Kolb, D; Reicher, H; Wagner, B; Stojakovic, T; Ruelicke, T; Haemmerle, G; Hoefler, G; Sattler, W; Kratky, D Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(4):500-511 Doi: 10.1016/j.bbalip.2019.01.007 [OPEN ACCESS]
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** Liu, L; Panzitt, K; Racedo, S; Wagner, M; Platzer, W; Zaufel, A; Theiler-Schwetz, V; Obermayer-Pietsch, B; Müller, H; Höfler, G; Heinemann, A; Zollner, G; Fickert, P Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1PR2, ERK and SF-1.
Liver Int. 2019; 39(11):2112-2123 Doi: 10.1111/liv.14052 [OPEN ACCESS]
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** Maneikyte, J; Bausys, A; Leber, B; Horvath, A; Feldbacher, N; Hoefler, G; Strupas, K; Stiegler, P; Schemmer, P Dietary glycine decreases both tumor volume and vascularization in a combined colorectal liver metastasis and chemotherapy model.
Int J Biol Sci. 2019; 15(8):1582-1590 Doi: 10.7150/ijbs.35513 [OPEN ACCESS]
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** Maresch, LK; Benedikt, P; Feiler, U; Eder, S; Zierler, KA; Taschler, U; Kolleritsch, S; Eichmann, TO; Schoiswohl, G; Leopold, C; Wieser, BI; Lackner, C; Rülicke, T; van, Klinken, J; Kratky, D; Moustafa, T; Hoefler, G; Haemmerle, G Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity.
Hepatol Commun. 2019; 3(2):227-245 Doi: 10.1002/hep4.1292 [OPEN ACCESS]
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** Nybo, T; Dieterich, S; Gamon, LF; Chuang, CY; Hammer, A; Hoefler, G; Malle, E; Rogowska-Wrzesinska, A; Davies, MJ Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase.
Redox Biol. 2019; 20:496-513 Doi: 10.1016/j.redox.2018.10.022 [OPEN ACCESS]
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** Pajed, L; Wagner, C; Taschler, U; Schreiber, R; Kolleritsch, S; Fawzy, N; Pototschnig, I; Schoiswohl, G; Pusch, LM; Wieser, BI; Vesely, P; Hoefler, G; Eichmann, TO; Zimmermann, R; Lass, A Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation.
J Biol Chem. 2019; 294(23):9118-9133 Doi: 10.1074/jbc.RA118.007201 [OPEN ACCESS]
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** Papp, R; Nagaraj, C; Zabini, D; Nagy, BM; Lengyel, M; Skofic Maurer, D; Sharma, N; Egemnazarov, B; Kovacs, G; Kwapiszewska, G; Marsh, LM; Hrzenjak, A; Höfler, G; Didiasova, M; Wygrecka, M; Sievers, LK; Szucs, P; Enyedi, P; Ghanim, B; Klepetko, W; Olschewski, H; Olschewski, A Targeting TMEM16A to reverse vasoconstriction and remodelling in idiopathic pulmonary arterial hypertension.
Eur Respir J. 2019; 53(6): 1800965 Doi: 10.1183/13993003.00965-2018
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** Richtig, G; Aigelsreiter, AM; Asslaber, M; Weiland, T; Pichler, M; Eberhard, K; Sygulla, S; Schauer, S; Hoefler, G; Aigelsreiter, A Hedgehog pathway proteins SMO and GLI expression as prognostic markers in head and neck squamous cell carcinoma.
Histopathology. 2019; 75(1):118-127 Doi: 10.1111/his.13860 [OPEN ACCESS]
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** Schwarzenbacher, D; Klec, C; Pasculli, B; Cerk, S; Rinner, B; Karbiener, M; Ivan, C; Barbano, R; Ling, H; Wulf-Goldenberg, A; Stanzer, S; Rinnerthaler, G; Stoeger, H; Bauernhofer, T; Haybaeck, J; Hoefler, G; Jahn, SW; Parrella, P; Calin, GA; Pichler, M MiR-1287-5p inhibits triple negative breast cancer growth by interaction with phosphoinositide 3-kinase CB, thereby sensitizing cells for PI3Kinase inhibitors.
Breast Cancer Res. 2019; 21(1):20 Doi: 10.1186/s13058-019-1104-5 [OPEN ACCESS]
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** Vanichkitrungruang, S; Chuang, CY; Hawkins, CL; Hammer, A; Hoefler, G; Malle, E; Davies, MJ Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function.
Free Radic Biol Med. 2019; 136(Suppl 1): 118-134. Doi: 10.1016/j.freeradbiomed.2019.04.003
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Abstract (Journal)

** Perakis, SO; Ulz, P; Riedl, JM; Scheipner, L; Kashofer, K; Hoefler, G; Geigl, JB; Speicher, MR; Heitzer, E; Gerger, A Molecular-biological tumor profiling for drug treatment selection in patients with advanced and refractory carcinoma: A prospective, two-stage Phase II individualized cancer treatment study
CANCER RES. 2019; 79(13):-Annual Meeting of the American-Association-for-Cancer-Research (AACR); MAR 29-APR 03, 2019; Atlanta, GA. Doi: 10.1158/1538-7445.AM2019-CT130 [Poster]
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2018

Full paper/article (Journal)

** Alkan, HF; Walter, KE; Luengo, A; Madreiter-Sokolowski, CT; Stryeck, S; Lau, AN; Al-Zoughbi, W; Lewis, CA; Thomas, CJ; Hoefler, G; Graier, WF; Madl, T; Vander Heiden, MG; Bogner-Strauss, JG Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting.
Cell Metab. 2018; 28(5):706-720 Doi: 10.1016/j.cmet.2018.07.021 [OPEN ACCESS]
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** Al-Zoughbi, W; Schauer, S; Pichler, M; Hoefler, G Early Loss of Forkhead Transcription Factor, O Subgroup, Member 1 Protein in the Development of Pancreatic Ductal Adenocarcinoma.
Pathobiology. 2018; 85(5-6): 342-347. Doi: 10.1159/000492433 [OPEN ACCESS]
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** Caraffini, V; Perfler, B; Berg, JL; Uhl, B; Schauer, S; Kashofer, K; Ghaffari-Tabrizi-Wizsy, N; Strobl, H; Wölfler, A; Hoefler, G; Sill, H; Zebisch, A Loss of RKIP is a frequent event in myeloid sarcoma and promotes leukemic tissue infiltration.
Blood. 2018; 131(7): 826-830. Doi: 10.1182/blood-2017-09-804906 [OPEN ACCESS]
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** Degendorfer, G; Chuang, CY; Mariotti, M; Hammer, A; Hoefler, G; Hägglund, P; Malle, E; Wise, SG; Davies, MJ Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function.
Free Radic Biol Med. 2018; 115:219-231 Doi: 10.1016/j.freeradbiomed.2017.11.019
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** Gaksch, L; Kashofer, K; Heitzer, E; Quehenberger, F; Daga, S; Hofer, S; Halbwedl, I; Graf, R; Krisper, N; Hoefler, G; Zebisch, A; Sill, H; Wölfler, A Residual disease detection using targeted parallel sequencing predicts relapse in cytogenetically normal acute myeloid leukemia.
Am J Hematol. 2018; 93(1):23-30 Doi: 10.1002/ajh.24922 [OPEN ACCESS]
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Short report/Letter

** Kashofer, K; Gornicec, M; Lind, K; Caraffini, V; Schauer, S; Beham-Schmid, C; Wölfler, A; Hoefler, G; Sill, H; Zebisch, A Detection of prognostically relevant mutations and translocations in myeloid sarcoma by next generation sequencing.
Leuk Lymphoma. 2018; 59(2):501-504 Doi: 10.1080/10428194.2017.1339879 [OPEN ACCESS]
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** Robier, C; Hoefler, G; Egger, M; Hubmann, E Atypical "hairy cell-like" presentation of leukemic mantle cell lymphoma.
Clin Chem Lab Med. 2018; 57(2): e34-e36-e34-e36. Doi: 10.1515/cclm-2018-0633
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** Schulz, E; Lind, K; Renner, W; Petersen, BS; Quehenberger, F; Dill, C; Hofer, S; Lal, R; Hoefler, G; Schlenke, P; Ehninger, G; Schetelig, J; Middeke, JM; Stölzel, F; Sill, H The TP53 Pro72Arg SNP in de novo acute myeloid leukaemia - results of two cohort studies involving 215 patients and 3759 controls.
Br J Haematol. 2018; 181(1):148-151 Doi: 10.1111/bjh.14527 [OPEN ACCESS]
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Abstract (Journal)

** Caraffini, V; Geiger, O; Rosenberger, A; Hatzl, S; Perfler, B; Berg, JL; Lim, C; Strobl, H; Kashofer, K; Hoefler, G; Geissler, K; Kolch, W; Blyth, K; Athineos, D; Wolfler, A; Sill, H; Zebisch, A Loss of RKIP expression is a frequent event in chronic myelomonocytic leukemia and functionally involved in the pathogenesis of this malignancy
ONCOL RES TREAT. 2018; 41: 27-27. [Oral Communication]
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** Degendorfer, G; Lorentzen, L; Chuang, C; Mariotti, M; Hammer, A; Hoefler, G; Hagglund, P; Malle, E; Davies, M; Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function.
FREE RADICAL BIOL MED. 2018; 128: S31-S31.-25th Annual Meeting of the Society-for-Redox-Biology-and-Medicine (SfRBM); NOV 14-17, 2018; Chicago, IL. Doi: 10.1016/j.freeradbiomed.2018.10.032 [Oral Communication]
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** Degendorfer, G; Lorentzen, LG; Chuang, CY; Mariotti, M; Hammer, A; Hoefler, G; Hagglund, P; Malle, E; Wise, S; Davies, MJ Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function
FREE RADICAL BIO MED. 2018; 120: S102-S103.-19th Biennial Meeting of the Society-for-Free-Radical-Research-International (SFRRI); 2018; Lisbon, PORTUGAL. Doi: 10.1016/j.freeradbiomed.2018.04.339 [Oral Communication]
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** Kashofer, K; Halbwedl, I; Winter, E; Hoefler, G; Asslaber, M Expanding on WHO guideline compliant molecular testing of central nervous system tumours by low density whole genome sequencing
VIRCHOWS ARCH. 2018; 473: S28-S28.-ECP European Congress of Pathology; SEP 8-12,2018; Bilbao, SPAIN. [Oral Communication]
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** Kashofer, K; Winter, E; Reich, O; Hoefler, G; Regauer, S Time series analysis of TP53 gene mutations in recurrent vulvar cancer
VIRCHOWS ARCH. 2018; 473: S33-S33. [Oral Communication]
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** Koeller, M; Berger, M; Eder, S; Richtig, G; Richtig, E; Pichler, M; Winter, G; Hoefler, G; Aigelsreiter, A. Is microsatellite-instability a prognostic factor in melanoma patients treated with immune-checkpoint inhibitors?
VIRCHOWS ARCH. 2018; 473: S9-S10. [Oral Communication]
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** Larose, H; Mian, S; Nuglozeh, E; Fazaludeen, FMS; Elmouna, A; Ashankyty, I; Du, MQ; Hoefler, G; Pospisilova, S; Woessmann, W; Damm-Welk, C; Fedorova, A; Lamant, L; Schlederer, M; Merkel, O; Kenner, L; Turner, SD Investigating the functional impact of single nucleotide variants in anaplastic large cell lymphoma
BRIT J HAEMATOL. 2018; 182: 41-42.-6th International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin Lymphoma; SEP 26-29, 2018; Rotterdam, NETHERLANDS. [Oral Communication]
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** Larose, H; Mian, SA; Nuglozeh, E; Fazaludeen, FM; Elmouna, AM; Ashankyty, I; Du, MQ; Hofler, G; Pospisilova, S; Woessmann, W; Damm-Welk, C; Fedorova, A; Lamant, L; Schlederer, M; Merkel, O; Kenner, L; Turner, SD Investigating the functional impacts of single-nucleotide variants in anaplastic large cell lymphoma
CANCER RES. 2018; 78(13):-Annual Meeting of the American-Association-for-Cancer-Research (AACR); APR 14-18, 2018; Chicago, IL. Doi: 10.1158/1538-7445.AM2018-1417 [Oral Communication]
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** Nybo, T; Deiterich, S; Gamon, L; Chuang, C; Hammer, A; Hoefler, G; Malle, E; Rogowska-Wrzesinska, A; Davies, M; Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase.
FREE RADICAL BIOL MED. 2018; 128: S49-S50.-25th Annual Meeting of the Society-for-Redox-Biology-and-Medicine (SfRBM); NOV 14-17, 2018; Chicago, IL. Doi: 10.1016/j.freeradbiomed.2018.10.084 [Oral Communication]
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** Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Doktorova, M; Scheicher, B; Goeritzer, M; Kolb, D; Turnbull, AV; Zimmer, A; Hoefler, G; Hussain, MM; Groen, AK; Kratky, D NOVEL ROLE OF A TRIGLYCERIDE-SYNTHESIZING ENZYME: DGAT1 AT THE CROSSROAD BETWEEN TRIGLYCERIDE AND CHOLESTEROL METABOLISM
ATHEROSCLEROSIS. 2018; 275: E10-E11.-86th Congress of the European-Atherosclerosis-Society (EAS); MAY 05-08, 2018; Lisbon, PORTUGAL. Doi: 10.1016/j.atherosclerosis.2018.06.915 [Oral Communication]
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2017

Full paper/article (Journal)

** Castellani, C; Singer, G; Kaiser, M; Kaiser, T; Huang, J; Sperl, D; Kashofer, K; Fauler, G; Guertl-Lackner, B; Höfler, G; Till, H Neuroblastoma causes alterations of the intestinal microbiome, gut hormones, inflammatory cytokines, and bile acid composition.
Pediatr Blood Cancer. 2017; 64(8): Doi: 10.1002/pbc.26425
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** Edlinger, L; Berger-Becvar, A; Menzl, I; Hoermann, G; Greiner, G; Grundschober, E; Bago-Horvath, Z; Al-Zoughbi, W; Hoefler, G; Brostjan, C; Gille, L; Moriggl, R; Spittler, A; Sexl, V; Hoelbl-Kovacic, A Expansion of BCR/ABL1⁺ cells requires PAK2 but not PAK1.
Br J Haematol. 2017; 179(2):229-241 Doi: 10.1111/bjh.14833 [OPEN ACCESS]
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** El-Heliebi, A; Kashofer, K; Fuchs, J; Jahn, SW; Viertler, C; Matak, A; Sedlmayr, P; Hoefler, G Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer.
Histochem Cell Biol. 2017; 148(2):105-115 Doi: 10.1007/s00418-017-1557-5 [OPEN ACCESS]
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** Grond, S; Radner, FPW; Eichmann, TO; Kolb, D; Grabner, GF; Wolinski, H; Gruber, R; Hofer, P; Heier, C; Schauer, S; Rülicke, T; Hoefler, G; Schmuth, M; Elias, PM; Lass, A; Zechner, R; Haemmerle, G Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation.
J Invest Dermatol. 2017; 137(2):403-413 Doi: 10.1016/j.jid.2016.09.025 [OPEN ACCESS]
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** Lal, R; Lind, K; Heitzer, E; Ulz, P; Aubell, K; Kashofer, K; Middeke, JM; Thiede, C; Schulz, E; Rosenberger, A; Hofer, S; Feilhauer, B; Rinner, B; Svendova, V; Schimek, MG; Rücker, FG; Hoefler, G; Döhner, K; Zebisch, A; Wölfler, A; Sill, H Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia.
Blood. 2017; 129(18): 2587-2591. Doi: 10.1182/blood-2016-11-751008 [OPEN ACCESS]
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** Pessentheiner, AR; Huber, K; Pelzmann, HJ; Prokesch, A; Radner, FPW; Wolinski, H; Lindroos-Christensen, J; Hoefler, G; Rülicke, T; Birner-Gruenberger, R; Bilban, M; Bogner-Strauss, JG APMAP interacts with lysyl oxidase-like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion.
FASEB J. 2017; 31(9):4088-4103 Doi: 10.1096/fj.201601337R [OPEN ACCESS]
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** Pichler, M; Stiegelbauer, V; Vychytilova-Faltejskova, P; Ivan, C; Ling, H; Winter, E; Zhang, X; Goblirsch, M; Wulf-Goldenberg, A; Ohtsuka, M; Haybaeck, J; Svoboda, M; Okugawa, Y; Gerger, A; Hoefler, G; Goel, A; Slaby, O; Calin, GA Genome-Wide miRNA Analysis Identifies miR-188-3p as a Novel Prognostic Marker and Molecular Factor Involved in Colorectal Carcinogenesis.
Clin Cancer Res. 2017; 23(5):1323-1333 Doi: 10.1158/1078-0432.CCR-16-0497 [OPEN ACCESS]
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** Richtig, G; Aigelsreiter, A; Schwarzenbacher, D; Ress, AL; Adiprasito, JB; Stiegelbauer, V; Hoefler, G; Schauer, S; Kiesslich, T; Kornprat, P; Winder, T; Eisner, F; Gerger, A; Stoeger, H; Stauber, R; Lackner, C; Pichler, M SOX9 is a proliferation and stem cell factor in hepatocellular carcinoma and possess widespread prognostic significance in different cancer types.
PLoS One. 2017; 12(11):e0187814-e0187814 Doi: 10.1371/journal.pone.0187814 [OPEN ACCESS]
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** Stiegelbauer, V; Vychytilova-Faltejskova, P; Karbiener, M; Pehserl, AM; Reicher, A; Resel, M; Heitzer, E; Ivan, C; Bullock, M; Ling, H; Deutsch, A; Wulf-Goldenberg, A; Adiprasito, JB; Stoeger, H; Haybaeck, J; Svoboda, M; Stotz, M; Hoefler, G; Slaby, O; Calin, GA; Gerger, A; Pichler, M miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5.
Clin Cancer Res. 2017; 23(17):5255-5266 Doi: 10.1158/1078-0432.CCR-17-0023 [OPEN ACCESS]
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Short report/Letter

** Richtig, G; Richtig, E; Kashofer, K; Koch, L; Winter, G; Hoefler, G; Pichler, M; Ehall, B; Grübler, MR; Heinemann, A; Aigelsreiter, A Testing and clinical implications for non-V600 BRAF mutations in metastatic NRAS^mt melanoma.
Br J Dermatol. 2017; 177(3):860-861 Doi: 10.1111/bjd.15222
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Abstract (Journal)

** Caraffini, V; Geiger, O; Rosenberger, A; Hatzl, S; Perfler, B; Berg, JL; Lim, C; Strobl, H; Kashofer, K; Hoefler, G; Geissler, K; Kolch, W; Blyth, K; Athineos, D; Woelfler, A; Sill, H; Zebisch, A LOSS OF RAF KINASE INHIBITOR PROTEIN IS INVOLVED IN MYELOMONOCYTIC LINEAGE COMMITMENT AND AGGRAVATES THE DEVELOPMENT OF CHRONIC MYELOMONOCYTIC LEUKEMIA IN A MURINE IN-VIVO MODEL
HAEMATOLOGICA. 2017; 102: 148-149.-22nd Congress of the European-Hematology-Association; JUN 22-25, 2017; Madrid, SPAIN. [Oral Communication]
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** Caraffini, V; Schauer, S; Kashofer, K; Wolfler, A; Hoefler, G; Sill, H; Zebisch, A RAF KINASE INHIBITOR PROTEIN IS INVOLVED IN THE DEVELOPMENT OF MYELOID SARCOMA
HAEMATOLOGICA. 2017; 102: 361-362.-22nd Congress of the European-Hematology-Association; JUN 22-25, 2017; Madrid, SPAIN. [Poster]
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** Gaksch, L; Kashofer, K; Heitzer, E; Daga, S; Hofer, S; Krisper, N; Hofler, G; Zebisch, A; Sill, H; Wolfler, A Persistence of non-DNMT3A mutations predicts relapse in cytogenetically normal AML
ONCOL RES TREAT. 2017; 40: 140-141. [Oral Communication]
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** Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Boverhof, R; Doktorova, M; Scheicher, B; Kolb, D; Turnbull, AV; Zimmer, A; Hoefler, G; Hussain, MM; Groen, AK; Kratky, D NOVEL ROLE OF A TRIGLYCERIDE-SYNTHESIZING ENZYME: DGAT1 AT THE CROSSROAD BETWEEN TRIGLYCERIDE AND CHOLESTEROL METABOLISM
ATHEROSCLEROSIS. 2017; 263: E7-E7.-85th Congress of the European-Atherosclerosis-Society (EAS); APR 23-26, 2017; Prague, CZECH REPUBLIC. Doi: 10.1016/j.atherosclerosis.2017.06.048 [Oral Communication]
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Comment

** Hoefler, G Next-Generation Sequencing in Diagnostics and Clinical Research.
Pathobiology. 2017; 84(6):289-291 Doi: 10.1159/000485366 [OPEN ACCESS]
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** Richtig, G; Aigelsreiter, AM; Sygulla, S; Schauer, S; Asslaber, M; Pichler, M; Höfler, G; Aigelsreiter, A Hedgehog pathway proteins SMO and GLI expression in head and neck squamous cell carcinoma – a potential therapeutic target?.
Virchows Arch. 2017; 471: S152-S152.-29th European Congress of Pathology; SEP 2-6, 2017; Amsterdam, The Netherlands. [Poster]
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2016

Full paper/article (Journal)

** Al-Zoughbi, W; Pichler, M; Gorkiewicz, G; Guertl-Lackner, B; Haybaeck, J; Jahn, SW; Lackner, C; Liegl-Atzwanger, B; Popper, H; Schauer, S; Nusshold, E; Kindt, AS; Trajanoski, Z; Speicher, MR; Haemmerle, G; Zimmermann, R; Zechner, R; Vesely, PW; Hoefler, G Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Oncotarget. 2016; 7(23):33832-33840 Doi: 10.18632/oncotarget.9418 [OPEN ACCESS]
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** Bonin, S; Donada, M; Bussolati, G; Nardon, E; Annaratone, L; Pichler, M; Chiaravalli, AM; Capella, C; Hoefler, G; Stanta, G A synonymous EGFR polymorphism predicting responsiveness to anti-EGFR therapy in metastatic colorectal cancer patients.
Tumour Biol. 2016; 37(6):7295-7303 Doi: 10.1007/s13277-015-4543-3
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** Endris, V; Stenzinger, A; Pfarr, N; Penzel, R; Möbs, M; Lenze, D; Darb-Esfahani, S; Hummel, M; Sabine-Merkelbach-Bruse, M; Jung, A; Lehmann, U; Kreipe, H; Kirchner, T; Büttner, R; Jochum, W; Höfler, G; Dietel, M; Weichert, W; Schirmacher, P NGS-based BRCA1/2 mutation testing of high-grade serous ovarian cancer tissue: results and conclusions of the first international round robin trial.
Virchows Arch. 2016; 468(6):697-705 Doi: 10.1007/s00428-016-1919-8
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** Huang, J; Li, L; Lian, J; Schauer, S; Vesely, PW; Kratky, D; Hoefler, G; Lehner, R Tumor-Induced Hyperlipidemia Contributes to Tumor Growth.
Cell Rep. 2016; 15(2): 336-348. Doi: 10.1016/j.celrep.2016.03.020 [OPEN ACCESS]
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** Kammerer, S; Sokolowski, A; Hackl, H; Platzer, D; Jahn, SW; El-Heliebi, A; Schwarzenbacher, D; Stiegelbauer, V; Pichler, M; Rezania, S; Fiegl, H; Peintinger, F; Regitnig, P; Hoefler, G; Schreibmayer, W; Bauernhofer, T KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients.
Oncotarget. 2016; 7(51):84705-84717 Doi: 10.18632/oncotarget.13224 [OPEN ACCESS]
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** Ling, H; Pickard, K; Ivan, C; Isella, C; Ikuo, M; Mitter, R; Spizzo, R; Bullock, M; Braicu, C; Pileczki, V; Vincent, K; Pichler, M; Stiegelbauer, V; Hoefler, G; Almeida, MI; Hsiao, A; Zhang, X; Primrose, J; Packham, G; Liu, K; Bojja, K; Gafà, R; Xiao, L; Rossi, S; Song, JH; Vannini, I; Fanini, F; Kopetz, S; Zweidler-McKay, P; Wang, X; Ionescu, C; Irimie, A; Fabbri, M; Lanza, G; Hamilton, SR; Berindan-Neagoe, I; Medico, E; Mirnezami, A; Calin, GA; Nicoloso, MS The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis.
Gut. 2016; 65(6):977-989 Doi: 10.1136/gutjnl-2015-309372 [OPEN ACCESS]
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** Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Boverhof, R; Doktorova, M; Scheicher, B; Goeritzer, M; Kolb, D; Turnbull, AV; Zimmer, A; Hoefler, G; Hussain, MM; Groen, AK; Kratky, D Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.
Biochim Biophys Acta. 2016; 1861(9 Pt A):1132-1141 Doi: 10.1016/j.bbalip.2016.06.014 [OPEN ACCESS]
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** Ulz, P; Belic, J; Graf, R; Auer, M; Lafer, I; Fischereder, K; Webersinke, G; Pummer, K; Augustin, H; Pichler, M; Hoefler, G; Bauernhofer, T; Geigl, JB; Heitzer, E; Speicher, MR Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer.
Nat Commun. 2016; 7(15):12008-12008 Doi: 10.1038/ncomms12008 [OPEN ACCESS]
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** Vujic, N; Schlager, S; Eichmann, TO; Madreiter-Sokolowski, CT; Goeritzer, M; Rainer, S; Schauer, S; Rosenberger, A; Woelfler, A; Doddapattar, P; Zimmermann, R; Hoefler, G; Lass, A; Graier, WF; Radovic, B; Kratky, D Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice.
Atherosclerosis. 2016; 244:9-21 Doi: 10.1016/j.atherosclerosis.2015.10.109 [OPEN ACCESS]
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** Wolf, P; Byrne, SN; Limon-Flores, AY; Hoefler, G; Ullrich, SE Serotonin signalling is crucial in the induction of PUVA-induced systemic suppression of delayed-type hypersensitivity but not local apoptosis or inflammation of the skin.
Exp Dermatol. 2016; 25(7):537-543 Doi: 10.1111/exd.12990 [OPEN ACCESS]
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Review

** Speicher, MR; Gerger, A; Hoefler, G Liquid biopsies. A multidisciplinary challenge for human geneticists, oncologists, and pathologists
MED GENET-BERLIN. 2016; 28(2): 245-250. Doi: 10.1007/s11825-016-0090-6 [OPEN ACCESS]
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** Stanta, G; Jahn, SW; Bonin, S; Hoefler, G Tumour heterogeneity: principles and practical consequences.
Virchows Arch. 2016; 469(4):371-384 Doi: 10.1007/s00428-016-1987-9
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Abstract (Journal)

** Gaksch, L; Kashofer, K; Heitzer, E; Daga, S; Hofer, S; Krisper, N; Höfler, G; Zebisch, A; Sill, H; Wölfler A Persitence of non-DNMT3A mutations predicts relapse in cytogenetically normal AML.
Oncol Res Treat 2016. 2016; 39(suppl3):140--Jahrestagung DGHO; OCT 14-18,2016; Leipzig. (ISBN: 2296-5270 ) [Oral Communication]
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** Kashofer, K; Brcic, L; Thueringer, A; Aigelsreiter, A; Popper, H; Hoefler, G Liquid biopsies in lung and skin cancer-a comparison of digital PCR and NGS methodologies
VIRCHOWS ARCH. 2016; 469: S42-S42. [Oral Communication]
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** Richtig, G; Ehall, B; Koch, L; Richtig, E; Winter, G; Eder, S; Kashofer, K; Heinemann, A; Hoefler, G; Aigelsreiter, A The clinical relevance of testing for non-V600E BRAF mutations in melanoma-a single center experience
VIRCHOWS ARCH. 2016; 469: S309-S309. [Oral Communication]
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** Riding, G; Ehall, B; Koch, L; Richtig, E; Winter, G; Eder, S; Kashofer, K; Heinemann, A; Hoefler, G; Aigelsreiter, A The relevance of BRAF exon 11 testing in melanoma-single center experience
VIRCHOWS ARCH. 2016; 469: S193-S193. [Poster]
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** Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Doktorova, M; Goeritzer, M; Scheicher, B; Kolb, D; Hoefler, G; Turnbull, AV; Zimmer, A; Hussain, MM; Groen, AK; Kratky, D LIPOPROTEINS AND LIPID METABOLISM: APOB CONTAINING LIPOPROTEINS. NOVEL ROLE OF A TRIGLYCERIDE-SYNTHESIZING ENZYME: DGAT1 AT THE CROSSROAD BETWEEN TRIGLYCERIDE AND CHOLESTEROL METABOLISM
ATHEROSCLEROSIS. 2016; 252: E98-E99.-Congress of the European-Atherosclerosis-Society (EAS); MAY 29-JUN 01, 2016; Innsbruck, AUSTRIA. Doi: 10.1016/j.atherosclerosis.2016.07.564
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** Vujic, N; Schlager, S; Eichmann, TO; Goeritzer, M; Madreiter-Sokolowski, CT; Schauer, S; Lass, A; Zimmermann, R; Hoefler, G; Graier, WF; Radovic, B; Kratky, D MONOGLYCERIDE LIPASE REGULATES ENDOCANNABINOID TONE AND ATHEROSCLEROTIC PLAQUE STRUCTURE IN APOLIPOPROTEIN E-DEFICIENT MICE
ATHEROSCLEROSIS. 2016; 252: E259-E259.-Congress of the European-Atherosclerosis-Society (EAS); MAY 29-JUN 01, 2016; Innsbruck, AUSTRIA. Doi: 10.1016/j.atherosclerosis.2016.07.086 [Oral Communication]
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2015

Full paper/article (Journal)

** Das, SK; Stadelmeyer, E; Schauer, S; Schwarz, A; Strohmaier, H; Claudel, T; Zechner, R; Hoefler, G; Vesely, PW Micro RNA-124a regulates lipolysis via adipose triglyceride lipase and comparative gene identification 58.
Int J Mol Sci. 2015; 16(4):8555-8568 Doi: 10.3390/ijms16048555 [OPEN ACCESS]
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** Hoffmann, J; Marsh, LM; Pieper, M; Stacher, E; Ghanim, B; Kovacs, G; König, P; Wilkens, H; Haitchi, HM; Hoefler, G; Klepetko, W; Olschewski, H; Olschewski, A; Kwapiszewska, G Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients.
Am J Physiol Lung Cell Mol Physiol. 2015; 308(10): L1002-L1013. Doi: 10.1152/ajplung.00383.2014 [OPEN ACCESS]
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** Jahn, SW; Kashofer, K; Halbwedl, I; Winter, G; El-Shabrawi-Caelen, L; Mentzel, T; Hoefler, G; Liegl-Atzwanger, B Mutational dichotomy in desmoplastic malignant melanoma corroborated by multigene panel analysis.
Mod Pathol. 2015; 28(7):895-903 Doi: 10.1038/modpathol.2015.39 [OPEN ACCESS]
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** Ravindran Menon, D; Das, S; Krepler, C; Vultur, A; Rinner, B; Schauer, S; Kashofer, K; Wagner, K; Zhang, G; Bonyadi Rad, E; Haass, NK; Soyer, HP; Gabrielli, B; Somasundaram, R; Hoefler, G; Herlyn, M; Schaider, H A stress-induced early innate response causes multidrug tolerance in melanoma.
Oncogene. 2015; 34(34):4448-4459 Doi: 10.1038/onc.2014.372 [OPEN ACCESS]
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** Ress, AL; Stiegelbauer, V; Winter, E; Schwarzenbacher, D; Kiesslich, T; Lax, S; Jahn, S; Deutsch, A; Bauernhofer, T; Ling, H; Samonigg, H; Gerger, A; Hoefler, G; Pichler, M MiR-96-5p influences cellular growth and is associated with poor survival in colorectal cancer patients.
Mol Carcinog. 2015; 54(11):1442-1450 Doi: 10.1002/mc.22218
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** Schwarzenbacher, D; Stiegelbauer, V; Deutsch, A; Ress, AL; Aigelsreiter, A; Schauer, S; Wagner, K; Langsenlehner, T; Resel, M; Gerger, A; Ling, H; Ivan, C; Calin, GA; Hoefler, G; Rinner, B; Pichler, M Low spinophilin expression enhances aggressive biological behavior of breast cancer.
Oncotarget. 2015; 6(13):11191-11202 Doi: 10.18632/oncotarget.3586 [OPEN ACCESS]
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** Schwarzl, M; Hamdani, N; Seiler, S; Alogna, A; Manninger, M; Reilly, S; Zirngast, B; Kirsch, A; Steendijk, P; Verderber, J; Zweiker, D; Eller, P; Höfler, G; Schauer, S; Eller, K; Maechler, H; Pieske, BM; Linke, WA; Casadei, B; Post, H A porcine model of hypertensive cardiomyopathy: implications for heart failure with preserved ejection fraction.
Am J Physiol Heart Circ Physiol. 2015; 309(9):H1407-18 Doi: 10.1152/ajpheart.00542.2015 [OPEN ACCESS]
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** Stotz, M; Szkandera, J; Stojakovic, T; Seidel, J; Samonigg, H; Kornprat, P; Schaberl-Moser, R; Seggewies, F; Hoefler, G; Gerger, A; Pichler, M The lymphocyte to monocyte ratio in peripheral blood represents a novel prognostic marker in patients with pancreatic cancer.
Clin Chem Lab Med. 2015; 53(3):499-506 Doi: 10.1515/cclm-2014-0447
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Short report/Letter

** Geiger, O; Hatzl, S; Kashofer, K; Hoefler, G; Wölfler, A; Sill, H; Zebisch, A Deletion of SPRY4 is a frequent event in secondary acute myeloid leukemia.
Ann Hematol. 2015; 94(11):1923-1924 Doi: 10.1007/s00277-015-2445-5 [OPEN ACCESS]
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** Schulz, E; Kashofer, K; Heitzer, E; Mhatre, KN; Speicher, MR; Hoefler, G; Sill, H Preexisting TP53 mutation in therapy-related acute myeloid leukemia.
Ann Hematol. 2015; 94(3):527-529 Doi: 10.1007/s00277-014-2191-0 (- Case Report) [OPEN ACCESS]
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Abstract (Journal)

** Heitzer, E; Ulz, P; Auer, M; Belic, J; Sumitra, M; Lax, S; Hoefler, G; Augustin, H; Edgar, P; Bauernhofer, T; Geigl, J; Speicher, M Clinical utility of circulating tumor DNA in human cancers: A report of more than 300 plama-Seqs
EUR J CANCER. 2015; 51: S33-S33.-European Cancer Congress; Sep 25-29, 2015; Vienna, AUSTRIA. Doi: 10.1016/S0959-8049(16)30108-3 [Poster]
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** Matak, A; Jahn, S; Viertler, C; Thuringer, A; Halbwedl, I; Langner, C; Hoefler, G; Kashofer, K Genetic heterogeneity of colorectal carcinoma in NGS analysis: A complication for molecular diagnosis?
VIRCHOWS ARCH. 2015; 467: S166-S167.-European Congress of Pathology; SEP 5-9, 2015; Belgrade, SERBIA. [Poster]
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** Menon, D; Das, S; Krepler, C; Vultur, A; Schauer, S; Kashofer, K; Haass, NK; Soyer, HP; Gabrielli, B; Somasundaram, R; Hoefler, G; Herlyn, M; Schaider, H A stress induced early innate response causes multi-drug tolerance in melanoma
EXP DERMATOL. 2015; 24(3):E35-E35.-42nd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF); MAR 05-07, 2015; Ulm, GERMANY. [Oral Communication]
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** Menon, DR; Das, S; Krepler, C; Vultur, A; Zhang, G; Haass, N; Soyer, PH; Gabrielli, B; Somasundaram, R; Hoefler, G; Herlyn, M; Schaider, H An early innate stress response precedes acquired drug resistance in melanoma
CANCER RES. 2015; 75: Doi: 10.1158/1538-7445.AM2015-2684
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** Schwarzenbacher, D; Stiegelbauer, V; Deutsch, A; Ress, AL; Aigelsreiter, A; Schauer, S; Gerger, A; Hofler, G; Rinner, B; Pichler, M Low spinophilin expression is associated with poor prognosis and cellular growth in human breast cancer
ANN ONCOL. IMPAKT Breast Cancer Conference. 2015; 26: -IMPAKT Breast Cancer Conference; MAY 07-09, 2015; Brussels, BELGIUM. Doi: 10.1093/annonc/mdv120.6 [Poster]
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** Vinod, M; Patankar, JV; Sachdev, V; Al-Zoughbi, WAEL; Hofler, G; Frank, SASA; Graier, WF; Kratky, D; Kostner, GM MICRO-RNA 206 AFFECTS GLUCOSE INDUCED INSULIN SECRETION UNDER HIGH-FAT DIET
ATHEROSCLEROSIS. 2015; 241(1):E83-E83.-83rd Congress of the European-Atherosclerosis-Society (EAS); MAR 22-25, 2015; Glasgow, SCOTLAND. Doi: 10.1016/j.atherosclerosis.2015.04.292 [Poster]
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2014

Full paper/article (Journal)

** Eisterer, W; De Vries, A; Öfner, D; Rabl, H; Koplmüller, R; Greil, R; Tschmelitsch, J; Schmid, R; Kapp, K; Lukas, P; Sedlmayer, F; Höfler, G; Gnant, M; Thaler, J; Austrian Breast and Colorectal Cancer Study Group (ABCSG) Preoperative treatment with capecitabine, cetuximab and radiotherapy for primary locally advanced rectal cancer--a phase II clinical trial.
Anticancer Res. 2014; 34(11):6767-6773
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** Graulich, T; Das, SK; Wessels, L; Kummer, W; Hoefler, G; Mühlfeld, C Effects of Lewis lung carcinoma and B16 melanoma on the innervation of the mouse trachea.
Auton Neurosci. 2014; 183(Pt 4):106-110 Doi: 10.1016/j.autneu.2014.03.005
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** Heitzer, E; Artl, M; Filipits, M; Resel, M; Graf, R; Weißenbacher, B; Lax, S; Gnant, M; Wrba, F; Greil, R; Dietze, O; Hofbauer, F; Böhm, G; Höfler, G; Samonigg, H; Schaberl-Moser, R; Balic, M; Dandachi, N Differential survival trends of stage II colorectal cancer patients relate to promoter methylation status of PCDH10, SPARC, and UCHL1.
Mod Pathol. 2014; 27(6):906-915 Doi: 10.1038/modpathol.2013.204 [OPEN ACCESS]
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** Jha, P; Claudel, T; Baghdasaryan, A; Mueller, M; Halilbasic, E; Das, SK; Lass, A; Zimmermann, R; Zechner, R; Hoefler, G; Trauner, M Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia.
Hepatology. 2014; 59(3):858-869 Doi: 10.1002/hep.26732 [OPEN ACCESS]
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** Jha, P; Knopf, A; Koefeler, H; Mueller, M; Lackner, C; Hoefler, G; Claudel, T; Trauner, M; Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH).
BBA-MOL BASIS DIS. 2014; 1842(7): 959-970. Doi: 10.1016/j.bbadis.2014.02.012 [OPEN ACCESS]
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** Koller, K; Pichler, M; Koch, K; Zandl, M; Stiegelbauer, V; Leuschner, I; Hoefler, G; Guertl, B Nephroblastomas show low expression of microR-204 and high expression of its target, the oncogenic transcription factor MEIS1.
Pediatr Dev Pathol. 2014; 17(3):169-175 Doi: 10.2350/13-01-1288-OA.1
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** Mohan, S; Heitzer, E; Ulz, P; Lafer, I; Lax, S; Auer, M; Pichler, M; Gerger, A; Eisner, F; Hoefler, G; Bauernhofer, T; Geigl, JB; Speicher, MR Changes in colorectal carcinoma genomes under anti-EGFR therapy identified by whole-genome plasma DNA sequencing.
PLoS Genet. 2014; 10(3):e1004271-e1004271 Doi: 10.1371/journal.pgen.1004271 [OPEN ACCESS]
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** Pichler, M; Ress, AL; Winter, E; Stiegelbauer, V; Karbiener, M; Schwarzenbacher, D; Scheideler, M; Ivan, C; Jahn, SW; Kiesslich, T; Gerger, A; Bauernhofer, T; Calin, GA; Hoefler, G MiR-200a regulates epithelial to mesenchymal transition-related gene expression and determines prognosis in colorectal cancer patients.
Br J Cancer. 2014; 110(6):1614-1621 Doi: 10.1038/bjc.2014.51 [OPEN ACCESS]
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** Pichler, M; Winter, E; Ress, AL; Bauernhofer, T; Gerger, A; Kiesslich, T; Lax, S; Samonigg, H; Hoefler, G miR-181a is associated with poor clinical outcome in patients with colorectal cancer treated with EGFR inhibitor.
J Clin Pathol. 2014; 67(3):198-203 Doi: 10.1136/jclinpath-2013-201904
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** Schrammel, A; Mussbacher, M; Wölkart, G; Stessel, H; Pail, K; Winkler, S; Schweiger, M; Haemmerle, G; Al Zoughbi, W; Höfler, G; Lametschwandtner, A; Zechner, R; Mayer, B Endothelial dysfunction in adipose triglyceride lipase deficiency.
Biochim Biophys Acta. 2014; 1841(6):906-917 Doi: 10.1016/j.bbalip.2014.03.005 [OPEN ACCESS]
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** Schulz, E; Klampfl, P; Holzapfel, S; Janecke, AR; Ulz, P; Renner, W; Kashofer, K; Nojima, S; Leitner, A; Zebisch, A; Wölfler, A; Hofer, S; Gerger, A; Lax, S; Beham-Schmid, C; Steinke, V; Heitzer, E; Geigl, JB; Windpassinger, C; Hoefler, G; Speicher, MR; Boland, CR; Kumanogoh, A; Sill, H Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.
Nat Commun. 2014; 5(10):5191-5191 Doi: 10.1038/ncomms6191 [OPEN ACCESS]
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** Stotz, M; Szkandera, J; Seidel, J; Stojakovic, T; Samonigg, H; Reitz, D; Gary, T; Kornprat, P; Schaberl-Moser, R; Hoefler, G; Gerger, A; Pichler, M Evaluation of uric acid as a prognostic blood-based marker in a large cohort of pancreatic cancer patients.
PLoS One. 2014; 9(8):e104730-e104730 Doi: 10.1371/journal.pone.0104730 [OPEN ACCESS]
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** Szkandera, J; Stotz, M; Absenger, G; Stojakovic, T; Samonigg, H; Kornprat, P; Schaberl-Moser, R; Alzoughbi, W; Lackner, C; Ress, AL; Seggewies, FS; Gerger, A; Hoefler, G; Pichler, M Validation of C-reactive protein levels as a prognostic indicator for survival in a large cohort of pancreatic cancer patients.
Br J Cancer. 2014; 110(1):183-188 Doi: 10.1038/bjc.2013.701 [OPEN ACCESS]
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** van Harten, W; Stanta, G; Bussolati, G; Riegman, P; Hoefler, G; Becker, K; Folprecht, G; Truini, M; Haybaeck, J; Buiga, R; Dono, M; Bagg, A; López Guerrero, J; Zupo, S; Lemare, F; de Lorenzo, F; Goedbloed, N; Razavi, D; Lövey, J; Cadariu, P; Rollandi, G; Paparo, F; Pierotti, M; Ciuleanu, T; De Paoli, P; Weiner, G; Saghatchian, M; Lombardo, C Report from the OECI Oncology Days 2014.
Ecancermedicalscience. 2014; 8(4):496-496 Doi: 10.3332/ecancer.2014.496 [OPEN ACCESS]
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** Vytrva, N; Stacher, E; Regitnig, P; Zinke-Cerwenka, W; Hojas, S; Hubmann, E; Porwit, A; Bjorkholm, M; Hoefler, G; Beham-Schmid, C Megakaryocytic morphology and clinical parameters in essential thrombocythemia, polycythemia vera, and primary myelofibrosis with and without JAK2 V617F.
Arch Pathol Lab Med. 2014; 138(9):1203-1209 Doi: 10.5858/arpa.2013-0018-OA (- Case Report) [OPEN ACCESS]
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Review

** Al-Zoughbi, W; Al-Zhoughbi, W; Huang, J; Paramasivan, GS; Till, H; Pichler, M; Guertl-Lackner, B; Hoefler, G Tumor macroenvironment and metabolism.
Semin Oncol. 2014; 41(2):281-295 Doi: 10.1053/j.seminoncol.2014.02.005 [OPEN ACCESS]
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Abstract (Journal)

** Heitzer, E; Mohan, S; Ulz, P; Lafer, I; Auer, M; Lax, S; Hoefler, G; Bauernhofer, T; Geigl, JB; Speicher, MR; Changes in colorectal carcinoma genomes under anti-EGFR therapy identified by whole-genome plasma DNA sequencing.
EUR J CANCER. 2014; 50: S96-S96.-EACR 2014; München. Doi: 10.1016/S0959-8049(14)50357-7 [Poster]
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** Menon, DR; Das, S; Krepler, C; Vultur, A; Rinner, B; Schauer, S; Kashofer, K; Wagner, K; Zhang, G; Rad, EB; Soyer, HP; Gabrielli, B; Somasundaram, R; Hoefler, G; Herlyn, M; Schaider, H A stress induced early innate response causes multi-drug tolerance in melanoma
EUR J CANCER. 2014; 50: 34-34. Doi: 10.1016/S0959-8049(14)70219-9 [Poster]
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** Schulz, E; Kashofer, K; Mhatre, KN; Höfler, G; Sill, H SELECTION OF A PRE-EXISTING TP53 MUTATED CLONE IN THERAPY-RELATED ACUTE MYELOID LEUKEMIA
Haematologica. 2014; 99(S1):15-15.-19th Congress of the European Hematology Association; JUNE 12-15, 2014; Milan, ITALY. [Poster]
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** Schulz, E; Klampfl, P; Holzapfel, S; Janecke, AR; Ulz, P; Renner, W; Kashofer, K; Najima, S; Leitner, A; Zebisch, A; Wölfler, A; Hofer, S; Gerger, A; Lax, S; Beham-Schmid, C; Steinke, V; Geigl, JB; Höfler, G; Speicher, MR; Boland, CR; Kumanogoh, A; Sill, H Germline variants in the semaphorin SEMA4A confer susceptibility to familial colorectal cancer type X
Oncol Res Treat. 2014; 37(S5):105-105.-Annual Meeting of the German, Austrian and Swiss Associations of Hematology and Medical Oncology; OCT 10-14, 2014; Hamburg, GERMANY. (ISBN: 978-3-318-02811-9 ) [Oral Communication]
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2013

Full paper/article (Journal)

** Dijkstra, JR; Heideman, DA; Meijer, GA; Boers, JE; 't Hart, NA; Diebold, J; Hirschmann, A; Hoefler, G; Winter, G; Miltenberger-Miltenyi, G; Pereira, SV; Richman, SD; Quirke, P; Rouleau, EL; Guinebretiere, JM; Tejpar, S; Biesmans, B; van Krieken, JH KRAS mutation analysis on low percentage of colon cancer cells: the importance of quality assurance.
Virchows Arch. 2013; 462(1):39-46 Doi: 10.1007/s00428-012-1356-2
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** Doddapattar, P; Radović, B; Patankar, JV; Obrowsky, S; Jandl, K; Nusshold, C; Kolb, D; Vujić, N; Doshi, L; Chandak, PG; Goeritzer, M; Ahammer, H; Hoefler, G; Sattler, W; Kratky, D Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice.
Mol Nutr Food Res. 2013; 57(10):1718-1728 Doi: 10.1002/mnfr.201200794 [OPEN ACCESS]
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** Eißmann, M; Melzer, IM; Fernández, SB; Michel, G; Hrabě de Angelis, M; Hoefler, G; Finkenwirth, P; Jauch, A; Schoell, B; Grez, M; Schmidt, M; Bartholomae, CC; Newrzela, S; Haetscher, N; Rieger, MA; Zachskorn, C; Mittelbronn, M; Zörnig, M Overexpression of the anti-apoptotic protein AVEN contributes to increased malignancy in hematopoietic neoplasms.
Oncogene. 2013; 32(20):2586-2591 Doi: 10.1038/onc.2012.263 [OPEN ACCESS]
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** Grinschgl, I; Mannweiler, S; Holzapfel-Bauer, M; Pferschy, U; Hoefler, G; Guertl, B The role of morphology in combination with ploidy analysis in characterizing early gestational abortion.
Virchows Arch. 2013; 462(2):175-182 Doi: 10.1007/s00428-012-1350-8
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** Heitzer, E; Auer, M; Gasch, C; Pichler, M; Ulz, P; Hoffmann, EM; Lax, S; Waldispuehl-Geigl, J; Mauermann, O; Lackner, C; Höfler, G; Eisner, F; Sill, H; Samonigg, H; Pantel, K; Riethdorf, S; Bauernhofer, T; Geigl, JB; Speicher, MR Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing.
Cancer Res. 2013; 73(10):2965-2975 Doi: 10.1158/0008-5472.CAN-12-4140 [OPEN ACCESS]
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** Heitzer, E; Auer, M; Hoffmann, EM; Pichler, M; Gasch, C; Ulz, P; Lax, S; Waldispuehl-Geigl, J; Mauermann, O; Mohan, S; Pristauz, G; Lackner, C; Höfler, G; Eisner, F; Petru, E; Sill, H; Samonigg, H; Pantel, K; Riethdorf, S; Bauernhofer, T; Geigl, JB; Speicher, MR Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer.
Int J Cancer. 2013; 133(2):346-356 Doi: 10.1002/ijc.28030 [OPEN ACCESS]
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** Heitzer, E; Ulz, P; Belic, J; Gutschi, S; Quehenberger, F; Fischereder, K; Benezeder, T; Auer, M; Pischler, C; Mannweiler, S; Pichler, M; Eisner, F; Haeusler, M; Riethdorf, S; Pantel, K; Samonigg, H; Hoefler, G; Augustin, H; Geigl, JB; Speicher, MR Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing.
Genome Med. 2013; 5(4):30-30 Doi: 10.1186/gm434 [OPEN ACCESS]
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** Huang, J; Das, SK; Jha, P; Al Zoughbi, W; Schauer, S; Claudel, T; Sexl, V; Vesely, P; Birner-Gruenberger, R; Kratky, D; Trauner, M; Hoefler, G The PPARα agonist fenofibrate suppresses B-cell lymphoma in mice by modulating lipid metabolism.
Biochim Biophys Acta. 2013; 1831(10):1555-1565 Doi: 10.1016/j.bbalip.2013.04.012 [OPEN ACCESS]
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** Koenig, S; Schernthaner, M; Maechler, H; Kappe, CO; Glasnov, TN; Hoefler, G; Braune, M; Wittchow, E; Groschner, K A TRPC3 blocker, ethyl-1-(4-(2,3,3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (Pyr3), prevents stent-induced arterial remodeling.
J Pharmacol Exp Ther. 2013; 344(1):33-40 Doi: 10.1124/jpet.112.196832 [OPEN ACCESS]
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** Koller, K; Das, S; Leuschner, I; Korbelius, M; Hoefler, G; Guertl, B Identification of the transcription factor HOXB4 as a novel target of miR-23a.
Genes Chromosomes Cancer. 2013; 52(8):709-715 Doi: 10.1002/gcc.22066
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** Kollmann, K; Heller, G; Schneckenleithner, C; Warsch, W; Scheicher, R; Ott, RG; Schäfer, M; Fajmann, S; Schlederer, M; Schiefer, AI; Reichart, U; Mayerhofer, M; Hoeller, C; Zöchbauer-Müller, S; Kerjaschki, D; Bock, C; Kenner, L; Hoefler, G; Freissmuth, M; Green, AR; Moriggl, R; Busslinger, M; Malumbres, M; Sexl, V A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis.
Cancer Cell. 2013; 24(2):167-181 Doi: 10.1016/j.ccr.2013.07.012 [OPEN ACCESS]
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** Mayer, N; Schweiger, M; Romauch, M; Grabner, GF; Eichmann, TO; Fuchs, E; Ivkovic, J; Heier, C; Mrak, I; Lass, A; Höfler, G; Fledelius, C; Zechner, R; Zimmermann, R; Breinbauer, R Development of small-molecule inhibitors targeting adipose triglyceride lipase.
Nat Chem Biol. 2013; 9(12):785-7 Doi: 10.1038/nchembio.1359 [OPEN ACCESS]
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** Obrowsky, S; Chandak, PG; Patankar, JV; Povoden, S; Schlager, S; Kershaw, EE; Bogner-Strauss, JG; Hoefler, G; Levak-Frank, S; Kratky, D Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling.
J Lipid Res. 2013; 54(2):425-435 Doi: 10.1194/jlr.M031716 [OPEN ACCESS]
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** Pichler, M; Hutterer, GC; Chromecki, TF; Jesche, J; Kampel-Kettner, K; Groselj-Strele, A; Hoefler, G; Pummer, K; Zigeuner, R Comparison of the 2002 and 2010 TNM classification systems regarding outcome prediction in clear cell and papillary renal cell carcinoma.
Histopathology. 2013; 62(2):237-246 Doi: 10.1111/his.12001
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** Senanayake, U; Koller, K; Pichler, M; Leuschner, I; Strohmaier, H; Hadler, U; Das, S; Hoefler, G; Guertl, B The pluripotent renal stem cell regulator SIX2 is activated in renal neoplasms and influences cellular proliferation and migration.
Hum Pathol. 2013; 44(3):336-345 Doi: 10.1016/j.humpath.2012.05.021
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** Staber, PB; Zhang, P; Ye, M; Welner, RS; Nombela-Arrieta, C; Bach, C; Kerenyi, M; Bartholdy, BA; Zhang, H; Alberich-Jorda, M; Lee, S; Yang, H; Ng, F; Zhang, JY; Leddin, M; Silberstein, LE; Hoefler, G; Orkin, SH; Gottgens, B; Rosenbauer, F; Huang, G; Tenen, DG; Sustained PU.1 Levels Balance Cell-Cycle Regulators to Prevent Exhaustion of Adult Hematopoietic Stem Cells.
MOL CELL. 2013; 49(5): 934-946. Doi: 10.1016/j.molcel.2013.01.007 [OPEN ACCESS]
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** Stotz, M; Gerger, A; Eisner, F; Szkandera, J; Loibner, H; Ress, AL; Kornprat, P; AlZoughbi, W; Zoughbi, WA; Seggewies, FS; Lackner, C; Stojakovic, T; Samonigg, H; Hoefler, G; Pichler, M Increased neutrophil-lymphocyte ratio is a poor prognostic factor in patients with primary operable and inoperable pancreatic cancer.
Br J Cancer. 2013; 109(2):416-421 Doi: 10.1038/bjc.2013.332 [OPEN ACCESS]
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** Szkandera, J; Stotz, M; Eisner, F; Absenger, G; Stojakovic, T; Samonigg, H; Kornprat, P; Schaberl-Moser, R; Alzoughbi, W; Ress, AL; Seggewies, FS; Gerger, A; Hoefler, G; Pichler, M External validation of the derived neutrophil to lymphocyte ratio as a prognostic marker on a large cohort of pancreatic cancer patients.
PLoS One. 2013; 8(11):e78225-e78225 Doi: 10.1371/journal.pone.0078225 [OPEN ACCESS]
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Short report/Letter

** Orendi, K; Emberger, W; Speicher, MR; Hoefler, G; Sill, H Molecular Cytogenetics and Multiplex Reverse-Transcriptase Polymerase Chain Reaction for Risk Stratification in Acute Myeloid Leukemia.
J Clin Oncol. 2013; 31(18):2360-2361 Doi: 10.1200/JCO.2013.48.8189 [OPEN ACCESS]
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** Zebisch, A; Hoefler, G; Quehenberger, F; Wölfler, A; Sill, H Mutant DNMT3A in acute myeloid leukemia: guilty of inducing genetic instability?
Leukemia. 2013; 27(8): 1777-1778. Doi: 10.1038/leu.2013.48 [OPEN ACCESS]
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Review

** Das, SK; Hoefler, G The role of triglyceride lipases in cancer associated cachexia.
Trends Mol Med. 2013; 19(5):292-301 Doi: 10.1016/j.molmed.2013.02.006 [OPEN ACCESS]
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Correction

** Stotz, M; Gerger, A; Eisner, F; Szkandera, J; Loibner, H; Ress, AL; Kornprat, P; Alzoughbi, W; Seggewies, FS; Lackner, C; Stojakovic, T; Samonigg, H; Hoefler, G; Pichler, M Increased neutrophil-lymphocyte ratio is a poor prognostic factor in patients with primary operable as well as inoperable pancreatic cancer.
Br J Cancer. 2013; 109(7): 2026-2026. Doi: 10.1038/bjc.2013.591 [OPEN ACCESS]
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Abstract (Journal)

** Graulich, T; Das, SK; Wessels, L; Kummer, W; Hofler, G; Muhlfeld, C Differential effect of Lewis lung carcinoma and B16 melanoma on tracheal innervation in mice
ONKOLOGIE. 2013; 36: 267-267. [Poster]
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** Heitzer, E; Ulz, P; Belic, J; Gutschi, S; Quehenberger, F; Auer, M; Augustin, H; Hoefler, G; Geigl, JB; Speicher, MR Tumor associated copy number changes identified by whole-genome sequencing in the circulation of patients with prostate cancer
EUR J CANCER. 2013; 49: S98-S98.-17th ECCO / 38th ESMO / 32nd ESTRO European Cancer Congress on Reinforcing Multidisciplinarity; SEP 27-OCT 01, 2013; Amsterdam, NETHERLANDS. [Oral Communication]
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** Menon, DR; Das, S; Rinner, B; Bonyadi Rad, E; Hoefler, G; Schaider, H; Cd271+ve drug tolerant stem like melanoma cells play a crucial role in resistance to BRAF inhibitors.
EXP DERMATOL. 2013; 22(3):E43-E43.-40th Annual Meeting of the Association-of-Dermatological-Research; MAR 14-16, 2013; Dessau, GERMANY. [Oral Communication]
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2012

Full paper/article (Journal)

** Betge, J; Pollheimer, MJ; Lindtner, RA; Kornprat, P; Schlemmer, A; Rehak, P; Vieth, M; Hoefler, G; Langner, C Intramural and extramural vascular invasion in colorectal cancer: prognostic significance and quality of pathology reporting.
Cancer. 2012; 118(3):628-638 Doi: 10.1002/cncr.26310 [OPEN ACCESS]
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** Dijkstra, JR; Opdam, FJ; Boonyaratanakornkit, J; Schönbrunner, ER; Shahbazian, M; Edsjö, A; Hoefler, G; Jung, A; Kotsinas, A; Gorgoulis, VG; Lpez-Ros, F; de Stricker, K; Rouleau, E; Biesmans, B; van Krieken, JH Implementation of formalin-fixed, paraffin-embedded cell line pellets as high-quality process controls in quality assessment programs for KRAS mutation analysis.
J Mol Diagn. 2012; 14(3):187-191 Doi: 10.1016/j.jmoldx.2012.01.002 [OPEN ACCESS]
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** Graulich, T; Das, SK; Krasteva, G; Ruppert, C; Wessels, L; Hoefler, G; Mühlfeld, C Cancer cachexia alters intracellular surfactant metabolism but not total alveolar surface area.
Histochem Cell Biol. 2012; 138(5):803-813 Doi: 10.1007/s00418-012-0995-3
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** Laimer, D; Dolznig, H; Kollmann, K; Vesely, PW; Schlederer, M; Merkel, O; Schiefer, AI; Hassler, MR; Heider, S; Amenitsch, L; Thallinger, C; Staber, PB; Simonitsch-Klupp, I; Artaker, M; Lagger, S; Turner, SD; Pileri, S; Piccaluga, PP; Valent, P; Messana, K; Landra, I; Weichhart, T; Knapp, S; Shehata, M; Todaro, M; Sexl, V; Höfler, G; Piva, R; Medico, E; Ruggeri, BA; Cheng, M; Eferl, R; Egger, G; Penninger, JM; Jaeger, U; Moriggl, R; Inghirami, G; Kenner, L PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
Nat Med. 2012; 18(11):1699-1704 Doi: 10.1038/nm.2966 [OPEN ACCESS]
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** Moustafa, T; Fickert, P; Magnes, C; Guelly, C; Thueringer, A; Frank, S; Kratky, D; Sattler, W; Reicher, H; Sinner, F; Gumhold, J; Silbert, D; Fauler, G; Höfler, G; Lass, A; Zechner, R; Trauner, M Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Gastroenterology. 2012; 142(1):140-151 Doi: 10.1053/j.gastro.2011.09.051
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** Patankar, JV; Obrowsky, S; Doddapattar, P; Hoefler, G; Battle, M; Levak-Frank, S; Kratky, D Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis.
J Hepatol. 2012; 57(5):1061-1068 Doi: 10.1016/j.jhep.2012.06.028 [OPEN ACCESS]
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** Pichler, M; Hutterer, GC; Chromecki, TF; Jesche, J; Kampel-Kettner, K; Eberhard, K; Hoefler, G; Pummer, K; Zigeuner, R Trends of stage, grade, histology and tumour necrosis in renal cell carcinoma in a European centre surgical series from 1984 to 2010.
J Clin Pathol. 2012; 65(8):721-724 Doi: 10.1136/jclinpath-2012-200797
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** Pichler, M; Rainer, PP; Schauer, S; Hoefler, G Cardiac fibrosis in human transplanted hearts is mainly driven by cells of intracardiac origin.
J Am Coll Cardiol. 2012; 59(11): 1008-1016. Doi: 10.1016/j.jacc.2011.11.036 [OPEN ACCESS]
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** Pichler, M; Winter, E; Stotz, M; Eberhard, K; Samonigg, H; Lax, S; Hoefler, G; Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer.
Br J Cancer. 2012; 106(11):1826-1832 Doi: 10.1038/bjc.2012.175 [OPEN ACCESS]
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** Rainer, PP; Doleschal, B; Kirk, JA; Sivakumaran, V; Saad, Z; Groschner, K; Maechler, H; Hoefler, G; Bauernhofer, T; Samonigg, H; Hutterer, G; Kass, DA; Pieske, B; von, Lewinski, D; Pichler, M Sunitinib causes dose-dependent negative functional effects on myocardium and cardiomyocytes.
BJU Int. 2012; 110(10):1455-62 Doi: 10.1111/j.1464-410X.2012.11134.x [OPEN ACCESS]
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** Schlick, K; Aigelsreiter, A; Pichler, M; Reitter, S; Neumeister, P; Hoefler, G; Beham-Schmid, C; Linkesch, W Histiocytic sarcoma - targeted therapy: novel therapeutic options? A series of 4 cases.
Onkologie. 2012; 35(7-8):447-450 Doi: 10.1159/000340066 (- Case Report)
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** Senanayake, U; Das, S; Vesely, P; Alzoughbi, W; Fröhlich, LF; Chowdhury, P; Leuschner, I; Hoefler, G; Guertl, B miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms.
Carcinogenesis. 2012; 33(5):1014-1021 Doi: 10.1093/carcin/bgs126 [OPEN ACCESS]
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** Tamilarasan, KP; Temmel, H; Das, SK; Al Zoughbi, W; Schauer, S; Vesely, PW; Hoefler, G Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity.
Cell Death Dis. 2012; 3(11):e354-e354 Doi: 10.1038/cddis.2012.91 [OPEN ACCESS]
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Short report/Letter

** Dijkstra, JR; van Krieken, JHJM; Opdam, FJM; Boonyaratanakornkit, J; Schonbrunner, ER; Shahbazian, M; Edsjo, A; Hoefler, G; Jung, A; Kotsinas, A; Gorgoulis, VG; Lopez-Rios, F; de Stricker, K; Rouleau, E; Biesmans, B; Do Pre-Analytical Parameters Explain KRAS Test Sensitivity Disparities? Reply.
J MOL DIAGN. 2012; 14(6): 632-633. Doi: 10.1016/j.jmoldx.2012.07.003
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** Fried, I; Wölfler, A; Quehenberger, F; Hoefler, G; Sill, H; Zebisch, A Mutations inDNMT3A and loss of RKIP are independent events in acute monocytic leukemia.
Haematologica. 2012; 97(12):1936-1937 Doi: 10.3324/haematol.2012.068429 [OPEN ACCESS]
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Abstract (Journal)

** Menon, DR; Das, S; Rinner, B; Heike, K; Bonyadi Rad, E; Hoefler, G; Schaider, H; Transient CD271+ve Drug Tolerant Stem Like Melanoma Cells Are Inherently Resistant Towards BRAF And MEK Inhibition.
J INVEST DERMATOL. . 2012; 132: S124-S124.-42nd Annual Meeting of the European-Society-for-Dermatological-Research (ESDR); SEP 07-10, 2012; Venice, ITALY. [Oral Communication]
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** Patankar, J; Obrowsky, S; Hoefler, G; Battle, M; Kratky, D; Levak-Frank, S INTESTINAL DEFICIENCY OF GATA4 PROTECTS FROM DIET-INDUCED HEPATIC STEATOSIS BY SUPPRESSING DE NOVO LIPOGENESIS AND GLUCONEOGENESIS IN MICE
J HEPATOL. 2012; 56: S496-S496.-47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN. Doi: 10.1016/S0168-8278(12)61265-3 [Poster]
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Comment

** van Krieken, JH; Hoefler, G The times have changed: molecular pathology is here to stay. A commentary on: analytical performance of a PCR assay for the detection of KRAS mutations (codons 12/13 and 61) in formalin-fixed paraffin-embedded tissue samples of colorectal carcinoma, by Lee et al. In this issue.
VIRCHOWS ARCH. 2012; 460(2): 129-130. Doi: 10.1007/s00428-012-1197-z [OPEN ACCESS]
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2011

Full paper/article (Journal)

** Betge, J; Pollheimer, MJ; Schlemmer, A; Hoefler, G; Langner, C Gastric cancer and concomitant renal cancer: a systematic immunohistochemical and molecular analysis.
Oncol Rep. 2011; 26(3):567-575 Doi: 10.3892/or.2011.1346 [OPEN ACCESS]
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** Chandak, PG; Obrowsky, S; Radovic, B; Doddapattar, P; Aflaki, E; Kratzer, A; Doshi, LS; Povoden, S; Ahammer, H; Hoefler, G; Levak-Frank, S; Kratky, D Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice.
Biochim Biophys Acta. 2011; 1811(12): 1011-1020. Doi: 10.1016/j.bbalip.2011.08.010 [OPEN ACCESS]
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** Das, SK; Eder, S; Schauer, S; Diwoky, C; Temmel, H; Guertl, B; Gorkiewicz, G; Tamilarasan, KP; Kumari, P; Trauner, M; Zimmermann, R; Vesely, P; Haemmerle, G; Zechner, R; Hoefler, G Adipose triglyceride lipase contributes to cancer-associated cachexia.
Science. 2011; 333(6039):233-238 Doi: 10.1126/science.1198973 [OPEN ACCESS]
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** Grill, C; Sunitsch, S; Hatz, M; Hauser-Kronberger, C; Leuschner, I; Hoefler, G; Guertl, B Activation of beta-catenin is a late event in the pathogenesis of nephroblastomas and rarely correlated with genetic changes of the APC gene.
Pathology. 2011; 43(7):702-706 Doi: 10.1097/PAT.0b013e32834bf65c
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** Guertl, B; Senanayake, U; Nusshold, E; Leuschner, I; Mannweiler, S; Ebner, B; Hoefler, G Lim1, an embryonal transcription factor, is absent in multicystic renal dysplasia, but reactivated in nephroblastomas.
PATHOBIOLOGY. 2011; 78(4): 210-219. Doi: 10.1159/000326769 [OPEN ACCESS]
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** Haemmerle, G; Moustafa, T; Woelkart, G; Büttner, S; Schmidt, A; van, de, Weijer, T; Hesselink, M; Jaeger, D; Kienesberger, PC; Zierler, K; Schreiber, R; Eichmann, T; Kolb, D; Kotzbeck, P; Schweiger, M; Kumari, M; Eder, S; Schoiswohl, G; Wongsiriroj, N; Pollak, NM; Radner, FP; Preiss-Landl, K; Kolbe, T; Rülicke, T; Pieske, B; Trauner, M; Lass, A; Zimmermann, R; Hoefler, G; Cinti, S; Kershaw, EE; Schrauwen, P; Madeo, F; Mayer, B; Zechner, R ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.
Nat Med. 2011; 17(9):1076-85 Doi: 10.1038/nm.2439 [OPEN ACCESS]
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** Hörl, G; Wagner, A; Cole, LK; Malli, R; Reicher, H; Kotzbeck, P; Köfeler, H; Höfler, G; Frank, S; Bogner-Strauss, JG; Sattler, W; Vance, DE; Steyrer, E Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.
J Biol Chem. 2011; 286(19):17338-17350 Doi: 10.1074/jbc.M111.234534 [OPEN ACCESS]
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** Mühlfeld, C; Das, SK; Heinzel, FR; Schmidt, A; Post, H; Schauer, S; Papadakis, T; Kummer, W; Hoefler, G Cancer induces cardiomyocyte remodeling and hypoinnervation in the left ventricle of the mouse heart.
PLoS One. 2011; 6(5):e20424-e20424 Doi: 10.1371/journal.pone.0020424 [OPEN ACCESS]
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** Patankar, JV; Chandak, PG; Obrowsky, S; Pfeifer, T; Diwoky, C; Uellen, A; Sattler, W; Stollberger, R; Hoefler, G; Heinemann, A; Battle, M; Duncan, S; Kratky, D; Levak-Frank, S Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice.
Am J Physiol Endocrinol Metab. 2011; 300(3): E478-E488. Doi: 10.1152/ajpendo.00457.2010 [OPEN ACCESS]
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** Pinent, M; Prokesch, A; Hackl, H; Voshol, PJ; Klatzer, A; Walenta, E; Panzenboeck, U; Kenner, L; Trajanoski, Z; Hoefler, G; Bogner-Strauss, JG Adipose triglyceride lipase and hormone-sensitive lipase are involved in fat loss in JunB-deficient mice.
Endocrinology. 2011; 152(7):2678-2689 Doi: 10.1210/en.2010-1477 [OPEN ACCESS]
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Short report/Letter

** Jahn, SW; Winter, G; Stacher, E; Halbwedl, I; Gattenlöhner, S; Stockinger, R; Spreitzer, S; Waldispuehl-Geigl, J; Geigl, JB; Offner, F; Hoefler, G Multiple intratumoral KRAS mutations can clonally segregate to different lymph node metastases in colon cancer.
Histopathology. 2011; 59(2): 342-345. Doi: 10.1111/j.1365-2559.2011.03902.x (- Case Report)
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Abstract (Journal)

** Kumari, P; Claudel, T; Kofeler, H; Schittmayer, M; Grunberger, RB; Baghdasaryan, A; Das, S; Zechner, R; Hofler, G; Trauner, M ADIPOSE TRIGLYCERIDE LIPASE (PNPLA2) IS A NOVEL KEY PLAYER IN PROTECTION FROM NASH
HEPATOLOGY. 2011; 54: 1154A-1154A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA. [Poster]
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2010

Full paper/article (Journal)

** Bonin, S; Hlubek, F; Benhattar, J; Denkert, C; Dietel, M; Fernandez, PL; Höfler, G; Kothmaier, H; Kruslin, B; Mazzanti, CM; Perren, A; Popper, H; Scarpa, A; Soares, P; Stanta, G; Groenen, PJ Multicentre validation study of nucleic acids extraction from FFPE tissues.
Virchows Arch. 2010; 457(3): 309-317. Doi: 10.1007/s00428-010-0917-5 [OPEN ACCESS]
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** Grill, C; Guelly, C; Ebner, B; Leuschner, I; Hauser-Kronberger, C; Hoefler, G; Guertl, B Loss of PTEN/MMAC1 activity is a rare and late event in the pathogenesis of nephroblastomas.
Hum Pathol. 2010; 41(8):1172-1177 Doi: 10.1016/j.humpath.2009.10.024
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** Guertl, B; Leuschner, I; Guelly, C; Ebner, B; Kronberger, C; Hoefler, G Is Predisposition for Nephroblastoma Linked to Polymorphisms of the WTX Gene?
Pathol Oncol Res. 2010; 16(2):189-191 Doi: 10.1007/s12253-009-9205-6
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** Hartmann, S; Gesk, S; Scholtysik, R; Kreuz, M; Bug, S; Vater, I; Doring, C; Cogliatti, S; Parrens, M; Merlio, JP; Kwiecinska, A; Porwit, A; Piccaluga, PP; Pileri, S; Hoefler, G; Kuppers, R; Siebert, R; Hansmann, ML High resolution SNP array genomic profiling of peripheral T cell lymphomas, not otherwise specified, identifies a subgroup with chromosomal aberrations affecting the REL locus.
BRIT J HAEMATOL. 2010; 148(3): 402-412. Doi: 10.1111/j.1365-2141.2009.07956.x
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** Nardon, E; Glavač, D; Benhattar, J; Groenen, PJ; Höfler, G; Höfler, H; Jung, A; Keller, G; Kirchner, T; Lessi, F; Ligtenberg, MJ; Mazzanti, CM; Winter, G; Stanta, G A multicenter study to validate the reproducibility of MSI testing with a panel of 5 quasimonomorphic mononucleotide repeats.
Diagn Mol Pathol. 2010; 19(4):236-242 Doi: 10.1097/PDM.0b013e3181db67af
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** Pichler, M; Beckendorf, J; Winter, E; Kleinert, R; Kniepeiss, D; Hoefler, G Quantitative short-tandem repeat analysis of recipient-derived cells as an additional tool for diagnosing cardiac allograft rejection.
Transplantation. 2010; 89(6): 749-755. Doi: 10.1097/TP.0b013e3181cab05c [OPEN ACCESS]
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** Radner, FP; Streith, IE; Schoiswohl, G; Schweiger, M; Kumari, M; Eichmann, TO; Rechberger, G; Koefeler, HC; Eder, S; Schauer, S; Theussl, HC; Preiss-Landl, K; Lass, A; Zimmermann, R; Hoefler, G; Zechner, R; Haemmerle, G Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).
J Biol Chem. 2010; 285(10):7300-11 Doi: 10.1074/jbc.M109.081877 [OPEN ACCESS]
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** Schoiswohl, G; Schweiger, M; Schreiber, R; Gorkiewicz, G; Preiss-Landl, K; Taschler, U; Zierler, KA; Radner, FP; Eichmann, TO; Kienesberger, PC; Eder, S; Lass, A; Haemmerle, G; Alsted, TJ; Kiens, B; Hoefler, G; Zechner, R; Zimmermann, R Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids.
J Lipid Res. 2010; 51(3): 490-9. Doi: 10.1194/jlr.M001073 [OPEN ACCESS]
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Abstract (Journal)

** Haller, M; Zebisch, A; Hiden, K; Hoefler, G; Sill, H; Troppmair, J Loss of RAF kinase inhibitor protein is a somatic event in the pathogenesis of therapy-related acute myeloid leukemias with C-RAF germline mutations
FEBS J. 2010; 277: 127-127. [Poster]
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** Harbaum, L; Pollheimer, M; Kornprat, P; Lindtner, R; Schlemmer, A; Rehak, P; Hoefler, G; Langner, C Acquisition of Keratin 7 Expression during Neoplastic Progression of Colorectal Cancer Indicates Aggressive Phenotype
ONKOLOGIE. 2010; 33: 68-68. [Poster]
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** Harbaum, L; Pollheimer, MJ; Kornprat, P; Lindtner, RA; Schlemmer, A; Rehak, P; Hoefler, G; Langner, C KERATIN 7 EXPRESSION IN COLORECTAL CANCER - FREAK OF NATURE OR SIGNIFICANT FINDING?
ANN ONCOL. 2010; 21: I38-I38. [Poster]
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** Hoefler, G Standardization and controls of methods for molecular analysis in archive tissues
VIRCHOWS ARCHIV. 2010; 457(2): 99-100. [Poster]
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** Kollmann, K; Ott, R; Heller, G; Schneckenleithner, C; Warsch, W; Schmatz, A; Zoechbauer-Mueller, S; Kenner, L; Hoefler, G; Freissmuth, M; Malumbres, M; Sexl, V CDK6 AS TUMOR SUPPRESSOR OR PROMOTER-P16INK4A MAKES ALL THE DIFFERENCE
HAEMATOL-HEMATOL J. 2010; 95: 0091 [Poster]
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** Kumari, P; Claudel, T; Kofeler, H; Schittmayer, M; Grunberger, RB; Zechner, R; Hofler, G; Trauner, M ADIPOSE TRIGLYCERIDE LIPASE (ATGL) IS A NOVEL KEY PLAYER IN PROTECTION FROM ACUTE HEPATIC INFLAMMATION
J HEPATOL. 2010; 52: S19-S19.-International Liver Congress™ 2010 – the 45th annual meeting of the European Association for the Study of the Liver (EASL) ; APR 14 -18, 2010; Doi: 10.1016/S0168-8278(10)60045-1 [Oral Communication]
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2009

Full paper/article (Journal)

** Czermak, C; Wallner, SJ; Kresse, A; Schauer, S; Aigner, R; Hoefler, G; Lehofer, M; Liebmann, PM Baseline plasma epinephrine levels predict Wisconsin Card Sorting Test scores in healthy volunteers.
Psychoneuroendocrinology. 2009; 34(4):625-628 Doi: 10.1016/j.psyneuen.2008.10.015
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** Gürtl, B; Kratky, D; Guelly, C; Zhang, L; Gorkiewicz, G; Das, SK; Tamilarasan, KP; Hoefler, G Apoptosis and fibrosis are early features of heart failure in an animal model of metabolic cardiomyopathy.
Int J Exp Pathol. 2009; 90(3): 338-46. Doi: 10.1111/j.1365-2613.2009.00647.x [OPEN ACCESS]
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** Gurtl, B; Kratky, D; Guelly, C; Zhang, LF; Gorkiewicz, G; Das, SK; Tamilarasan, KP; Hoefler, G Apoptosis and fibrosis are early features of heart failure in an animal model of metabolic cardiomyopathy
INT J EXP PATHOL. 2009; 90(3): 338-346. Doi: 10.1111/j.1365-2613.2009.00647.x [OPEN ACCESS]
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** Kratzer, A; Buchebner, M; Pfeifer, T; Becker, TM; Uray, G; Miyazaki, M; Miyazaki-Anzai, S; Ebner, B; Chandak, PG; Kadam, RS; Calayir, E; Rathke, N; Ahammer, H; Radovic, B; Trauner, M; Hoefler, G; Kompella, UB; Fauler, G; Levi, M; Levak-Frank, S; Kostner, GM; Kratky, D Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia.
J Lipid Res. 2009; 50(2): 312-326. Doi: 10.1194/jlr.M800376-JLR200 [OPEN ACCESS]
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** Pichler, M; Balic, M; Stadelmeyer, E; Ausch, C; Wild, M; Guelly, C; Bauernhofer, T; Samonigg, H; Hoefler, G; Dandachi, N Evaluation of high-resolution melting analysis as a diagnostic tool to detect the BRAF V600E mutation in colorectal tumors.
J Mol Diagn. 2009; 11(2):140-147 Doi: 10.2353/jmoldx.2009.080100 [OPEN ACCESS]
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** Zebisch, A; Haller, M; Hiden, K; Goebel, T; Hoefler, G; Troppmair, J; Sill, H Loss of RAF kinase inhibitor protein is a somatic event in the pathogenesis of therapy-related acute myeloid leukemias with C-RAF germline mutations.
Leukemia. 2009; 23(6): 1049-1053. Doi: 10.1038/leu.2009.68 [OPEN ACCESS]
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Review

** Vesely, PW; Staber, PB; Hoefler, G; Kenner, L Translational regulation mechanisms of AP-1 proteins.
Mutat Res. 2009; 682(1):7-12 Doi: 10.1016/j.mrrev.2009.01.001
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Comment

** Jahn, S; Minai-Pour, MB; Speicher, MR; Reiner-Concin, A; Hoefler, G Comprehensive screening for Lynch syndrome: who can be the driving force in daily clinical practice?
J CLIN ONCOL. 2009; 27(13): 2292-2292. Doi: 10.1200/JCO.2009.22.0731 [OPEN ACCESS]
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2008

Full paper/article (Journal)

** Grill, M; Heinemann, A; Hoefler, G; Peskar, BA; Schuligoi, R Effect of endotoxin treatment on the expression and localization of spinal cyclooxygenase, prostaglandin synthases, and PGD2 receptors.
J Neurochem. 2008; 104(5): 1345-1357. Doi: 10.1111/j.1471-4159.2007.05078.x [OPEN ACCESS]
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** Reiner-Concin, A; Regitnig, P; Dinges, HP; Höfler, G; Lax, S; Müller-Holzner, E; Obrist, P; Rudas, M Practice of HER-2 immunohistochemistry in breast carcinoma in Austria.
Pathol Oncol Res. 2008; 14(3):253-259 Doi: 10.1007/s12253-008-9079-z
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** Schuller-Petrovic, S; Wölkart, G; Höfler, G; Neuhold, N; Freisinger, F; Brunner, F Tissue-toxic effects of phosphatidylcholine/deoxycholate after subcutaneous injection for fat dissolution in rats and a human volunteer.
Dermatol Surg. 2008; 34(4):529-542 Doi: 10.1111/j.1524-4725.2008.34128.x
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Review

** Ralmer, N; Hoefler, G; Hogenauer, C; Lackner, C; Steinke, V; Sengteller, M; Friedl, W; Aretz, S; Propping, P; Mangold, E; Walldorf, C Compound heterozygosity for two MSH6 mutations in a patient with early onset colorectal cancer, vitiligo and systemic lupus erythematosus.
AM J MED GENET PART A. 2008; 146A(10): 1314-1319. Doi: 10.1002/ajmg.a.32210 (- Case Report)
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** van Krieken, JH; Jung, A; Kirchner, T; Carneiro, F; Seruca, R; Bosman, FT; Quirke, P; Fléjou, JF; Plato Hansen, T; de Hertogh, G; Jares, P; Langner, C; Hoefler, G; Ligtenberg, M; Tiniakos, D; Tejpar, S; Bevilacqua, G; Ensari, A KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program.
Virchows Arch. 2008; 453(5): 417-431. Doi: 10.1007/s00428-008-0665-y [OPEN ACCESS]
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Abstract (Journal)

** Langner, C; Lindtner, RA; Pollheimer, MJ; Pollheimer, VS; Komprat, P; Schlemmer, A; Rehak, P; Kapp, K; Bergen, A; Hoefler, G Colorectal cancer in Styria/Southern Austria (CCS-Project): Changing patterns over a period of 20 years
ANN ONCOL. 2008; 19: I34-I34.-European Multidisciplinary Colorectal Cancer congress; FEB 24-26, 2008; Berlin, Deutschland. [Poster]
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** Pollheimer, VS; Pollheimer, MJ; Lindtner, RA; Hoefler, G; Schlemmer, A; Langner, C Is the syn- and/or metachronous occurrence of colorectal carcinoma and urothelial carcinoma of the upper urinary tract related to Lynch syndrome?
ANN ONCOL. 2008; 19: I35-I35. [Poster]
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2007

Full paper/article (Journal)

** McGovern, MM; Elles, R; Beretta, I; Somerville, MJ; Hoefler, G; Keinanen, M; Barton, D; Carson, N; Dequeker, E; Brdicka, R; Blazkova, A; Aymé, S; Schnieders, B; Muller, CR; Dalen, V; Martinez, AA; Kristoffersson, U; Ozguc, M; Mueller, H; Boone, J; Lubin, IM; Sequeiros, J; Taruscio, D; Williamson, B; Mainland, L; Yoshikura, H; Ronchi, E Report of an international survey of molecular genetic testing laboratories.
Community Genet. 2007; 10(3):123-131 Doi: 10.1159/000101753
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** Schratl, P; Royer, JF; Kostenis, E; Ulven, T; Sturm, EM; Waldhoer, M; Hoefler, G; Schuligoi, R; Lippe, IT; Peskar, BA; Heinemann, A The role of the prostaglandin D2 receptor, DP, in eosinophil trafficking.
J Immunol. 2007; 179(7):4792-4799 Doi: 10.4049/jimmunol.179.7.4792 [OPEN ACCESS]
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** Staber, PB; Vesely, P; Haq, N; Ott, RG; Funato, K; Bambach, I; Fuchs, C; Schauer, S; Linkesch, W; Hrzenjak, A; Dirks, WG; Sexl, V; Bergler, H; Kadin, ME; Sternberg, DW; Kenner, L; Hoefler, G The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling.
Blood. 2007; 110(9):3374-3383 Doi: 10.1182/blood-2007-02-071258 [OPEN ACCESS]
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** Wackernagel, A; Massone, C; Hoefler, G; Steinbauer, E; Kerl, H; Wolf, P Plasmacytoid dendritic cells are absent in skin lesions of polymorphic light eruption.
Photodermatol Photoimmunol Photomed. 2007; 23(1):24-28 Doi: 10.1111/j.1600-0781.2007.00267.x
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** Weber-Mzell, D; Urban, C; Benesch, M; Rojacher, T; Zois, B; Höfler, G; Schwinger, W Durable remission following a third allogeneic stem cell transplantation in a patient with repeatedly relapsing SAA. The importance of stroma cells for sustained engraftment?
Pediatr Transplant. 2007; 11(3):332-335 Doi: 10.1111/j.1399-3046.2006.00638.x (- Case Report)
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Abstract (Journal)

** Czermak, C; Wallner, SJ; Kresse, A; Schauer, S; Hoefler, G; Lemonis, L; Rohrhofer, A; Lehofer, M; Liebmann, PM Lymphocyte dopamine receptor D3 mRNA expression is positively correlated with Wisconsin Card Sorting Test perseveration scores in human male subjects
BIOL PSYCHIAT. 2007; 61(8):209S-209S. [Poster]
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** Fuchs, C; Vesely, P; Bambach, I; Schauer, S; Linkesch, W; Stemberg, DW; Hoefler, G; Staber, PB Identification of critical phosporylation sites within NPM-ALK that regulate JUNB mRNA translation
BLOOD. 2007; 110(11):1044A-1045A.-49 th Annual Meeting of the American Society of Hematology; NOV 8-11, 2007; Atlanta, Georgia, USA. [Poster]
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** Laimer, D; Vesely, P; Staber, P; Pflegerl, P; Brandes, R; Schlederer, M; Hoefler, G; Kenner, L Role of junb in ALCL lymphoma development
HAEMATOL-HEMATOL J. 2007; 92: 344-344.Vienna. [Poster]
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** Staber, P; Vesely, P; Fuchs, C; Bambach, I; Schauer, S; Bergler, H; Sternberg, D; Hoefler, G The oncoprotein NPM-ALK induces translation of AP-1 factors via mTOR signalling
HAEMATOL-HEMATOL J. 2007; 92: 344-344.Vienna. [Oral Communication]
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** Staber, PB; Vesely, P; Fuchs, C; Schauer, S; Sternberg, DW; Hoefler, G NPM-ALK induces JUNB and converts its role from a tumor suppressor to an oncogene
FEBS J. 2007; 274: 150-150. [Poster]
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** Vesely, P; Staber, P; Fuchs, C; Bambach, I; Schauer, S; Sternberg, D; Kenner, L; Hoefler, G Expression of NPM-ALK leads to oncogenic effects of JunB
HAEMATOL-HEMATOL J. 2007; 92: 107-107.Vienna. [Oral Communication]
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** Vesely, P; Staber, PB; Fuchs, C; Schauer, S; Bergler, H; Sternberg, DW; Hoefler, G Translational control of JUNB via the fusion tyrosine kinase NPM-ALK in ALC(L) lymphoma
FEBS J. 2007; 274: 150-150. [Poster]
Web of Science

 

** Wolf, P; Byrne, S; Ramos, G; Limon-Flores, AY; Hoefler, G; Ananthaswamy, HN; Ullrich, SE Mast cell-derived 5-HT is required for the induction of PUVA-induced systemic immune suppression but not local inflammation
J INVEST DERMATOL. 2007; 127: S41-S41. [Oral Communication]
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2006

Full paper/article (Journal)

** Guertl, B; Leuschner, I; Harms, D; Hoefler, G Genetic clonality is a feature unifying nephroblastomas regardless of the variety of morphological subtypes.
Virchows Arch. 2006; 449(2):171-174 Doi: 10.1007/s00428-006-0225-2
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** Haemmerle, G; Lass, A; Zimmermann, R; Gorkiewicz, G; Meyer, C; Rozman, J; Heldmaier, G; Maier, R; Theussl, C; Eder, S; Kratky, D; Wagner, EF; Klingenspor, M; Hoefler, G; Zechner, R Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.
SCIENCE. 2006; 312: 734-737. Doi: 10.1126/science.1123965 [OPEN ACCESS]
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** Langner, C; Rupar, G; Leibl, S; Hutterer, G; Chromecki, T; Hoefler, G; Rehak, P; Zigeuner, R Alpha-methylacyl-CoA racemase (AMACR/P504S) protein expression in urothelial carcinoma of the upper urinary tract correlates with tumour progression.
Virchows Arch. 2006; 448(3):325-330 Doi: 10.1007/s00428-005-0129-6
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** Staber, PB; Noehammer, C; Dürkop, H; Schauer, S; Kenner, L; Linkesch, W; Hoefler, G mRNA expression patterns indicate CD30 mediated activation of different apoptosis pathways in anaplastic large cell lymphoma but not in Hodgkin's lymphoma.
Leuk Res. 2006; 30(3):343-348 Doi: 10.1016/j.leukres.2005.08.010
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** Zebisch, A; Staber, PB; Delavar, A; Bodner, C; Hiden, K; Fischereder, K; Janakiraman, M; Linkesch, W; Auner, HW; Emberger, W; Windpassinger, C; Schimek, MG; Hoefler, G; Troppmair, J; Sill, H Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia.
Cancer Res. 2006; 66(7):3401-3408 Doi: 10.1158/0008-5472.CAN-05-0115 [OPEN ACCESS]
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Short report/Letter

** Neuhaus, O; Manda, VS; Scarpatetti, M; Höfler, G; Hartung, HP; Archelos, JJ New diagnostic options in tuberculous meningitis?
Int J Tuberc Lung Dis. 2006; 10(8):944-944
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Abstract (Journal)

** Haemmerle, G; Zimmermann, R; Lass, A; Hofler, G; Wagner, E; Zechner, R Adipose triglyceride lipase: Functional role in fat cell lipolysis and involvement in lipid and energy metabolism
ATHEROSCLER SUPPL. 7(3):15-15. Doi: 10.1016/S1567-5688(06)80037-1 [Poster]
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** Staber, PB; Vesely, P; Ott, R; Haq, N; Linkesch, W; Schauer, S; Hrzenjak, A; Kenner, L; Dirks, W; Kadin, ME; Sternberg, DW; Hoefler, G NPM-ALK fusion tyrosine kinase of anaplastic large cell lymphoma exerts its transforming potential by increasing translation of JUNB through mTOR and S6K1.
BLOOD. 2006; 108(11): 414A-415A. Doi: 10.1182/blood.V108.11.1428.1428 [Poster]
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** Vesely, P; Staber, PB; Ott, R; Pinent, M; Linkesch, W; Schauer, S; Hrzenjak, A; Kadin, ME; Sternberg, DW; Hoefler, G NPM-ALK converts JUNB from a tumor suppressor to an oncogene.
BLOOD. 2006; 108(11): 419A-420A. Doi: 10.1182/blood.V108.11.1448.1448 [Poster]
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** Wackernagel, A; Massone, C; Hoefler, G; Steinbauer, E; Kerl, H; Wolf, P Plasmacytoid dendritic cells are absent in skin lesions of polymorphic light eruption
J INVEST DERMATOL. 126: 140-140. [Poster]
Web of Science

 

2005

Review

** Lackner, C; Hoefler, G Critical issues in the identification and management of patients with hereditary non-polyposis colorectal cancer.
Eur J Gastroenterol Hepatol. 2005; 17(3):317-322 Doi: 10.1097%2F00042737-200503000-00010 [OPEN ACCESS]
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Abstract (Journal)

** Neuhaus, O; Manda, V; Scarpatetti, M; Hoefler, G; Hartung, H; Archelos, J Tuberculous meningitis - new diagnostic options?
J NEUROL 2005 252: 34-34.
Web of Science

 

Comment

** Lackner, C; Hoefler, G Clinical and genetic criteria are important for identification and management of hereditary non-polyposis colorectal cancer.
Eur J Gastroenterol Hepatol. 2005; 17(10):1143-1144 Doi: 10.1097/00042737-200510000-00023
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2004

Full paper/article (Journal)

** Jäger, G; Höfler, G; Linkesch, W; Neumeister, P Occurrence of a myelodysplastic syndrome (MDS) during first-line 2-chloro-deoxyadenosine (2-CDA) treatment of a low-grade gastrointestinal MALT lymphoma. Case report and review of the literature.
Haematologica. 2004; 89(4): ECR01-ECR01. (- Case Report) [OPEN ACCESS]
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** Lackner, C; Jukic, Z; Tsybrovskyy, O; Jatzko, G; Wette, V; Hoefler, G; Klimpfinger, M; Denk, H; Zatloukal, K Prognostic relevance of tumour-associated macrophages and von Willebrand factor-positive microvessels in colorectal cancer.
VIRCHOWS ARCHIV. 2004; 445(2): 160-167. Doi: 10.1007/s00428-004-1051-z
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** Staber, PB; Linkesch, W; Zauner, D; Beham-Schmid, C; Guelly, C; Schauer, S; Sill, H; Hoefler, G Common alterations in gene expression and increased proliferation in recurrent acute myeloid leukemia.
Oncogene. 2004; 23(4):894-904 Doi: 10.1038/sj.onc.1207192 [OPEN ACCESS]
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** Wolf, P; Seidl, H; Bäck, B; Binder, B; Höfler, G; Quehenberger, F; Hoffmann, C; Kerl, H; Stark, S; Pfister, HJ; Fuchs, PG Increased prevalence of human papillomavirus in hairs plucked from patients with psoriasis treated with psoralen-UV-A.
ARCH DERMATOL. 2004; 140(3): 317-324. Doi: 10.1001/archderm.140.3.317 [OPEN ACCESS]
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Abstract (Journal)

** Schwinger, W; Urban, C; Raicht, A; Dornbusch, H; Lackner, H; Sovinz, P; Benesch, M; Moser, A; Hofler, G T-cell reconstitution followed by TREC-analysis in children after allogeneic stem cell transplantation
BONE MARROW TRANSPLANT 2004 33: S334-S334.
Web of Science

 

** Staber, PB; Linkesch, W; Schauer, S; Moser, G; Kadin, ME; Dirks, W; Hoefler, G Genes regulated by NPM-ALK fusion kinase play a key role in the activation of AP-1 transcription factors.
BLOOD 2004 104: 74A-74A. Doi: 10.1182/blood.V104.11.245.245
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** Zebisch, A; Staber, PB; Fischereder, K; Bodner, C; Hiden, K; Linkesch, W; Auner, HW; Emberger, W; Windpassinger, C; Schimek, MG; Hoefler, G; Troppmair, J; Sill, H Two novel activating germline mutations of the C-RAF proto-oncogene predisposing to solid tbmors and therapy-related acute myeloid leukemia.
BLOOD 2004 104: 920A-920A. Doi: 10.1182/blood.V104.11.3370.3370
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** Zinke-Cerwenka, W; Eibl, M; Sill, H; Hofler, G; Staber, P; Linkesch, W Continuous molecular response after discontinuation of imatinib mesylate following relapse after non-myeloablative allogeneic stem cell transplantation for CML
BONE MARROW TRANSPLANT 2004 33: S348-S348.
Web of Science

 

2003

Full paper/article (Journal)

** Guertl, B; Ratschek, M; Harms, D; Jaenig, U; Leuschner, I; Poremba, C; Hoefler, G Clonality and loss of heterozygosity of WT genes are early events in the pathogenesis of nephroblastomas.
Hum Pathol. 2003; 34(3):278-281 Doi: 10.1053/hupa.2003.32
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** Högenauer, C; Langner, C; Lipp, RW; Höfler, G; Krejs, GJ; Hinterleitner, TA Complete remission of a metastatic gastrointestinal stromal tumour with the tyrosine kinase inhibitor imatinib (STI 571): effect of low dosage in an advanced tumour with exon 11 mutation.
Eur J Gastroenterol Hepatol. 2003; 15(3):323-327 Doi: 10.1097/01.meg.0000050013.68425.10 (- Case Report)
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** Nöhammer, C; Brunner, F; Wölkart, G; Staber, PB; Steyrer, E; Gonzalez, FJ; Zechner, R; Hoefler, G Myocardial dysfunction and male mortality in peroxisome proliferator-activated receptor alpha knockout mice overexpressing lipoprotein lipase in muscle.
Lab Invest. 2003; 83(2):259-269 Doi: 10.1097/01.LAB.0000053916.61772.CA [OPEN ACCESS]
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** Oettl, K; Höfler, G; Ness, GC; Sattler, W; Malle, E An apparent decrease in cholesterol biosynthesis in peroxisomal-defective Chinese hamster ovary cells is related to impaired mitochondrial oxidation.
BIOCHEM BIOPHYS RES COMMUN. 2003; 305(4): 957-963. Doi: 10.1016%2FS0006-291X%2803%2900855-6
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** Selenko-Gebauer, N; Majdic, O; Szekeres, A; Höfler, G; Guthann, E; Korthäuer, U; Zlabinger, G; Steinberger, P; Pickl, WF; Stockinger, H; Knapp, W; Stöckl, J B7-H1 (programmed death-1 ligand) on dendritic cells is involved in the induction and maintenance of T cell anergy.
J Immunol. 2003; 170(7):3637-3644 Doi: 10.4049/jimmunol.170.7.3637 [OPEN ACCESS]
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** Ziouzenkova, O; Perrey, S; Asatryan, L; Hwang, J; MacNaul, KL; Moller, DE; Rader, DJ; Sevanian, A; Zechner, R; Hoefler, G; Plutzky, J Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: evidence for an antiinflammatory role for lipoprotein lipase.
PROC NAT ACAD SCI USA 2003 100: 2730-2735. Doi: 10.1073/pnas.0538015100 [OPEN ACCESS]
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Abstract (Journal)

** Dorda, AF; Hammer, HF; Hoefler, G; Lackner, C; Giessauf, H Colon cancer despite a previously diagnosed adenoma
GASTROENTEROLOGY. 2003; 124(4): A648-A648. Doi: 10.1016/S0016-5085(03)83284-5
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** Höfler, G; Staber, PB; Beham-Schmid, C; Guelly, C; Schauer, S; Linkesch, W Increased proliferation rate and activation of the B-RAF/MEK/erk pathway at relapse of acute myeloid leukemia
LAB INVEST 2003 83: 235A-236A.
Web of Science

 

** Höfler, G; Staber, PB; Beham-Schmid, C; Guelly, C; Schauer, S; Linkesch, W Increased proliferation rate and activation of the B-RAF/MEK/Erk pathway at relapse of acute myeloid leukemia
MODERN PATHOL 2003 16: 235A-236A.
Web of Science

 

** Staber, PB; Neumeister, P; Duerkop, H; Schauer, S; Linkesch, W; Hoefler, G CD30 induced cell death in anaplastic large cell lymphoma involves perforin/granzyme cell death pathway and the caspase dependent death receptors TNFR-1 and FAS/APO-1.
BLOOD 2003 102: 885A-885A.
Web of Science

 

2002

Full paper/article (Journal)

** Beham-Schmid, C; Apfelbeck, U; Sill, H; Tsybrovsky, O; Höfler, G; Haas, OA; Linkesch, W Treatment of chronic myelogenous leukemia with the tyrosine kinase inhibitor STI571 results in marked regression of bone marrow fibrosis.
Blood. 2002; 99(1):381-383 Doi: 10.1182/blood.V99.1.381 [OPEN ACCESS]
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** Cerroni, L; Höfler, G; Bäck, B; Wolf, P; Maier, G; Kerl, H Specific cutaneous infiltrates of B-cell chronic lymphocytic leukemia (B-CLL) at sites typical for Borrelia burgdorferi infection.
J Cutan Pathol. 2002; 29(3):142-147 Doi: 10.1034%2Fj.1600-0560.2002.290303.x
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** Jäeger, G; Neumeister, P; Brezinschek, R; Höfler, G; Quehenberger, F; Linkesch, W; Sill, H Rituximab (anti-CD20 monoclonal antibody) as consolidation of first-line CHOP chemotherapy in patients with follicular lymphoma: a phase II study.
EUR J HAEMATOL 2002 69: 21-26. Doi: 10.1034%2Fj.1600-0609.2002.01692.x
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** Jäger, G; Neumeister, P; Brezinschek, R; Hinterleitner, T; Fiebiger, W; Penz, M; Neumann, HJ; Mlineritsch, B; DeSantis, M; Quehenberger, F; Chott, A; Beham-Schmid, C; Höfler, G; Linkesch, W; Raderer, M Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type with cladribine: a phase II study.
J Clin Oncol. 2002; 20(18):3872-3877 Doi: 10.1200/JCO.2002.05.117 [OPEN ACCESS]
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** Olipitz, W; Hopfinger, G; Aguiar, RC; Gunsilius, E; Girschikofsky, M; Bodner, C; Hiden, K; Linkesch, W; Hoefler, G; Sill, H Defective DNA-mismatch repair: a potential mediator of leukemogenic susceptibility in therapy-related myelodysplasia and leukemia.
Genes Chromosomes Cancer. 2002; 34(2):243-248 Doi: 10.1002/gcc.10059
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** Regitnig, P; Reiner, A; Dinges, HP; Höfler, G; Müller-Holzner, E; Lax, SF; Obrist, P; Rudas, M; Quehenberger, F Quality assurance for detection of estrogen and progesterone receptors by immunohistochemistry in Austrian pathology laboratories.
Virchows Arch. 2002; 441(4):328-334 Doi: 10.1007/s00428-002-0646-5
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** Wehrschütz, M; Stöger, H; Ploner, F; Hofmann, G; Wolf, G; Höfler, G; Krippl, P; Samonigg, H Seminoma metastases mimicking primary pancreatic cancer.
Onkologie. 2002; 25(4):371-373 Doi: 10.1159/000066057 (- Case Report)
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Abstract (Journal)

** Bernhart, E; Noehammer, C; Staber, P; Schaffer, P; Höfler, G; Koidl, B A mouse model of metabolic cardiomyopathy shows alterations of ventricular electrophysiology
BIOPHYS J 2002 82: 477-477.
Web of Science

 

** Staber, PB; Hoefler, G; Beham-Schmid, C; Guelly, C; Schauer, S; Linkesch, W Increased proliferation rate in acute myeloid leukemia blasts at relapse due to activation of the B-Raf/MEK/Erk pathway.
BLOOD 2002 100: 330A-330A.
Web of Science

 

** Ziouzenkova, O; Perry, S; Sukhova, G; Asatryan, L; Hwang, J; MacNaul, K; Moller, D; Rader, D; Sevanian, A; Zechner, R; Höfler, G; Plutzky, J Enzymatically active lipoprotein lipase generates endogenous PPAR-alpha ligands
CIRCULATION 2002 106: H-I.
Web of Science

 

2001

Full paper/article (Journal)

** Paschke, E; Milos, I; Kreimer-Erlacher, H; Hoefler, G; Beck, M; Hoeltzenbein, M; Kleijer, W; Levade, T; Michelakakis, H; Radeva, B Mutation analyses in 17 patients with deficiency in acid beta-galactosidase: three novel point mutations and high correlation of mutation W273L with Morquio disease type B.
Hum Genet. 2001; 109(2):159-166 Doi: 10.1007/s004390100570 (- Case Report)
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** Seidl, H; Kreimer-Erlacher, H; Bäck, B; Soyer, HP; Höfler, G; Kerl, H; Wolf, P Ultraviolet exposure as the main initiator of p53 mutations in basal cell carcinomas from psoralen and ultraviolet A-treated patients with psoriasis.
J Invest Dermatol. 2001; 117(2):365-370 Doi: 10.1046/j.0022-202x.2001.01413.x [OPEN ACCESS]
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Abstract (Journal)

** Apfelbeck, U; Eibl, M; Hoefler, G; Linkesch, W High-dose therapy and peripheral blood progenitor cell transplantation in elderly patients
BONE MARROW TRANSPLANT. 2001; 27: S315-S315.
Web of Science

 

2000

Full paper/article (Journal)

** Apfelbeck, U; Hoefler, G; Neumeister, P; Fonatsch, C; Linkesch, W; Sill, H Extramedullary T cell lymphoblastic transformation of chronic myeloid leukaemia successfully treated with matched unrelated donor bone marrow transplantation.
BONE MARROW TRANSPLANT 2000 26: 1111-1112. Doi: 10.1038/sj.bmt.1702665 (- Case Report) [OPEN ACCESS]
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** Cabras, AD; Kremer, M; Schulz, S; Werner, M; Hummel, M; Komminoth, P; Höfler, G; Höfler, H Quality assessment in diagnostic molecular pathology: experience from a German-Austrian-Swiss multicenter trial.
Virchows Arch. 2000; 437(1):46-51 Doi: 10.1007%2Fs004280000212
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** Cerroni, L; Arzberger, E; Pütz, B; Höfler, G; Metze, D; Sander, CA; Rose, C; Wolf, P; Rütten, A; McNiff, JM; Kerl, H Primary cutaneous follicle center cell lymphoma with follicular growth pattern.
Blood. 2000; 95(12):3922-3928 Doi: 10.1182/blood.V95.12.3922.012k08_3922_3928 [OPEN ACCESS]
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** Dodojacek, R; Höfler, G; Leschnik, B; Muntean, W A novel type of mutation at the propeptide cleavage site (AlA+1Thr) causing symptomatic protein C type II deficiency.
Thromb Res. 2000; 100(1):109-113 Doi: 10.1016%2FS0049-3848%2800%2900291-7 (- Case Report)
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** Guertl, B; Beham, A; Zechner, R; Stammberger, H; Hoefler, G Nasopharyngeal angiofibroma: an APC-gene-associated tumor?
Hum Pathol. 2000; 31(11):1411-1413 Doi: 10.1053/hupa.2000.19462
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** Lax, SF; Semlitsch, G; Noiges, R; Höfler, G Point mutation of thyrotropin receptors as the main cause of autonomously functioning thyroid nodules: experiences in the framework of our Styrian patients
Acta Med Austriaca. 2000; 27(2):49-50 Doi: 10.1046%2Fj.1563-2571.2000.00205.x
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** Neumeister, P; Hoefler, G; Beham-Schmid, C; Sill, H; Linkesch, W Complete remission of generalized relapsed extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type of the gastrointestinal tract after high-dose chemotherapy and autologous peripheral stem cell transplantation.
ANN HEMATOL 2000 79: 703-705. Doi: 10.1007%2Fs002770000203 (- Case Report)
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** Nöhammer, C; El-Shabrawi, Y; Schauer, S; Hiden, M; Berger, J; Forss-Petter, S; Winter, E; Eferl, R; Zechner, R; Hoefler, G cDNA cloning and analysis of tissue-specific expression of mouse peroxisomal straight-chain acyl-CoA oxidase.
EUR J BIOCHEM 2000 267: 1254-1260. Doi: 10.1046%2Fj.1432-1327.2000.01128.x [OPEN ACCESS]
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Review

** Guertl, B; Noehammer, C; Hoefler, G Metabolic cardiomyopathies.
INT J EXP PATHOL 2000 81: 349-372. Doi: 10.1046%2Fj.1365-2613.2000.00186.x [OPEN ACCESS]
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Abstract (Journal)

** Guertl, B; Noehammer, C; Kratky, D; Tessaro, B; Zechner, R; Hoefler, G New genes involved in the development of metabolic cardiomyopathies
J PATHOL 2000 192: 11A-11A.
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** Olipitz, W; Hopfinger, G; Hoefler, G; Girschikofsky, M; Bodner, C; Hiden, K; Aguiar, R; Linkesch, W; Sill, H Microsatellite instability but lack of alternations of genes targeted by defective DNA-mismatch repair in therapy-related MDS and leukemia.
BLOOD 2000 96: 104A-104A.
Web of Science

 

** Rosskopf, K; Wagner, T; Helmberg, W; Sipurzynski, S; Gilli, R; Eibl, M; Linkesch, W; Höfler, G; Lanzer, G CD34 positive compared to one-step positive-negative selection of autologous peripheral blood stem cells (PBSC)
TRANSFUSION 2000 40: 110S-110S.
Web of Science

 

** Schwarz, T; Ardjomand, N; Jesenik, F; Hoefler, G; El-Shabrawi, Y PCR analysis of IgH-chain and T-Cell receptor gamma gene rearrangement as an additive tool in the diagnosis of extraocular lymphomas.
INVEST OPHTHALMOL VISUAL SCI 2000 41: S791-S791.
Web of Science

 

** Stauber, RE; Hegenbarth, KS; Tiran, A; Höfler, G; Zatloukal, K; Stenzel, HC Phenotypic screening for hemochromatosis in 4000 Austrian military recruits.
HEPATOLOGY 2000 32: 1320-1320.
Web of Science

 

1999

Full paper/article (Journal)

** Auner, HW; Klintschar, M; Crevenna, R; Beham-Schmid, C; Hoefler, G; Mitterbauer, G; Linkesch, W; Sill, H Two case studies of chronic idiopathic neutropenia preceding acute myeloid leukaemia.
Br J Haematol. 1999; 105(2):431-433 Doi: 10.1046%2Fj.1365-2141.1999.01322.x (- Case Report) [OPEN ACCESS]
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** Auner, HW; Olipitz, W; Hoefler, G; Bodner, C; Konrad, D; Crevenna, R; Linkesch, W; Sill, H Mutational analysis of the DNA mismatch repair gene hMLH1 in myeloid leukaemias.
Br J Haematol. 1999; 106(3):706-708 Doi: 10.1046%2Fj.1365-2141.1999.01595.x [OPEN ACCESS]
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** el-Shabrawi, Y; Ardjomand, N; Faschinger, C; Höfler, G Lattice corneal dystrophy. Detection of a point mutation in the kerato-epithelin gene
Ophthalmologe. 1999; 96(6):405-407 Doi: 10.1007/s003470050426
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** El-Shabrawi, Y; Radner, H; Muellner, K; Langmann, G; Hoefler, G The role of UV-radiation in the development of conjunctival malignant melanoma.
Acta Ophthalmol Scand. 1999; 77(1):31-32 Doi: 10.1034/j.1600-0420.1999.770107.x [OPEN ACCESS]
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** Kenner, L; Beham-Schmid, C; Kerbl, R; Schmidt, HH; Sill, H; Hoefler, G ABL amplification in a patient with lymphoid blast crisis of chronic myelogenous leukaemia.
Virchows Arch. 1999; 434(3):255-257 Doi: 10.1007%2Fs004280050337 (- Case Report)
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** Noiges, R; Semlitsch, G; Höfler, G; Lax, SF TSH-Receptor-Mutations and Thyroid Autonomy - Comparison Between Singular and Multiple Autonomous Nudules
ACTA MED AUST 1999 26: 118-118.
Web of Science

 

** van Grunsven, EG; van Berkel, E; Mooijer, PA; Watkins, PA; Moser, HW; Suzuki, Y; Jiang, LL; Hashimoto, T; Hoefler, G; Adamski, J; Wanders, RJ Peroxisomal bifunctional protein deficiency revisited: resolution of its true enzymatic and molecular basis.
Am J Hum Genet. 1999; 64(1):99-107 Doi: 10.1086/302180 [OPEN ACCESS]
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Abstract (Journal)

** Dodojacek, R; Muntean, W; Hoefler, G A novel missense mutation at the propeptide cleavage site (Ala+1 Thr) causing symptomatic protein C type II deficiency
THROMB HAEMOST 1999 SUPPL: 566-567.
Web of Science

 

1998

Full paper/article (Journal)

** Beham-Schmid, C; Beham, A; Jakse, R; Auböck, L; Höfler, G Extranodal follicular dendritic cell tumour of the nasopharynx.
Virchows Arch. 1998; 432(3):293-298 Doi: 10.1007%2Fs004280050168 (- Case Report)
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** Beham-Schmid, C; Heider, KH; Hoefler, G; Zatloukal, K Expression of CD44 splice variant v10 in Hodgkin's disease is associated with aggressive behaviour and high risk of relapse.
J Pathol. 1998; 186(4):383-389 Doi: 10.1002/(SICI)1096-9896(199812)186:4<383::AID-PATH202>3.0.CO;2-A
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** Kenner, L; Schwarzl, F; Moshammer, H; Haas, F; Hoefler, G; Pierer, G Venous thrombosis in a replanted finger with underlying factor V Leiden mutation.
Br J Plast Surg. 1998; 51(1):57-58 Doi: 10.1016/S0007-1226(97)90176-4 (- Case Report)
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** Zenz, W; Bodó, Z; Plotho, J; Streif, W; Male, C; Bernert, G; Rauter, L; Ebetsberger, G; Kaltenbrunner, K; Kurnik, P; Lischka, A; Paky, F; Ploier, R; Höfler, G; Mannhalter, C; Muntean, W Factor V Leiden and prothrombin gene G 20210 A variant in children with ischemic stroke.
Thromb Haemost. 1998; 80(5):763-766 Doi: 10.1055/s-0037-1615355
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Short report/Letter

** El-Shabrawi, Y; Langmann, G; Hutter, H; Kenner, L; Hoefler, G Comparison of current methods and PCR for the diagnosis of metastatic disease in uveal malignant melanoma.
Ophthalmologica. 1998; 212(1):80-80
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Abstract (Journal)

** Auner, HW; Klintschar, M; Beham-Schmid, C; Hoefler, G; Crevenna, R; Linkesch, W Chronic idiopathic neutropenia - A preleukemic disorder?
BLOOD 1998 92: 208B-208B.
Web of Science

 

** Jager, G; Neumeister, P; Hinterleitner, T; Hofler, G; Brezinschek, R; Linkesch, W Cladribine (2-CDA) as a therapy for low-grade MALT-lymphoma: An organ-preserving therapeutic concept.
BLOOD 1998 92: 236B-237B.
Web of Science

 

1997

Full paper/article (Journal)

** Cerroni, L; Signoretti, S; Höfler, G; Annessi, G; Pütz, B; Lackinger, E; Metze, D; Giannetti, A; Kerl, H Primary cutaneous marginal zone B-cell lymphoma: a recently described entity of low-grade malignant cutaneous B-cell lymphoma.
Am J Surg Pathol. 1997; 21(11):1307-1315 Doi: 10.1097%2F00000478-199711000-00005
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** Hoefler, G; Noehammer, C; Levak-Frank, S; el-Shabrawi, Y; Schauer, S; Zechner, R; Radner, H Muscle-specific overexpression of human lipoprotein lipase in mice causes increased intracellular free fatty acids and induction of peroxisomal enzymes.
Biochimie. 1997; 79(2-3):163-168 Doi: 10.1016%2FS0300-9084%2897%2981509-X
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** Kammerer, S; Arnold, N; Gutensohn, W; Mewes, HW; Kunau, WH; Höfler, G; Roscher, AA; Braun, A Genomic organization and molecular characterization of a gene encoding HsPXF, a human peroxisomal farnesylated protein.
Genomics. 1997; 45(1):200-210 Doi: 10.1006/geno.1997.4914
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** Neumeister, P; Hoefler, G; Beham-Schmid, C; Schmidt, H; Apfelbeck, U; Schaider, H; Linkesch, W; Sill, H Deletion analysis of the p16 tumor suppressor gene in gastrointestinal mucosa-associated lymphoid tissue lymphomas.
Gastroenterology. 1997; 112(6):1871-1875 Doi: 10.1053%2Fgast.1997.v112.pm9178679
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** Popper, HH; Klemen, H; Hoefler, G; Winter, E Presence of mycobacterial DNA in sarcoidosis.
Hum Pathol. 1997; 28(7):796-800 Doi: 10.1016%2FS0046-8177%2897%2990152-0
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** Taus, P; Smola, M; Starz, I; Petru, E; Höfler, G; Kronberger, L Primary malignant non-Hodgkin's lymphoma of the breast: breast preserving therapy in 3 patients
Gynakol Geburtshilfliche Rundsch. 1997; 37(2):68-70 Doi: 10.1159/000272834
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** Wöckel, W; Höfler, G; Popper, HH; Morresi-Hauf, A Lymphoepithelioma-like lung carcinomas
Pathologe. 1997; 18(2):147-152 Doi: 10.1007/s002920050203 (- Case Report)
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1996

Full paper/article (Journal)

** Caira, F; Cherkaoui-Malki, M; Hoefler, G; Latruffe, N Cloning and tissue expression of two cDNAs encoding the peroxisomal 2-enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase in the guinea pig liver.
FEBS Lett. 1996; 378(1):57-60 Doi: 10.1016%2F0014-5793%2895%2901425-X [OPEN ACCESS]
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** Cerroni, L; Zenahlik, P; Höfler, G; Kaddu, S; Smolle, J; Kerl, H Specific cutaneous infiltrates of B-cell chronic lymphocytic leukemia: a clinicopathologic and prognostic study of 42 patients.
Am J Surg Pathol. 1996; 20(8):1000-1010 Doi: 10.1097%2F00000478-199608000-00009
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** Fickert, P; Ramschak, H; Kenner, L; Hoefler, G; Hinterleitner, TA; Petritsch, W; Klimpfinger, M; Krejs, GJ; Stauber, RE Acute Budd-Chiari syndrome with fulminant hepatic failure in a pregnant woman with factor V Leiden mutation.
Gastroenterology. 1996; 111(6):1670-1673 Doi: 10.1016/S0016-5085(96)70031-8 (- Case Report)
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** Kerbl, R; Urban, CE; Lackner, H; Höfler, G; Ambros, IM; Ratschek, M; Ambros, PF Connatal localized neuroblastoma. The case to delay treatment.
Cancer. 1996; 77(7):1395-1401 Doi: 10.1002/(SICI)1097-0142(19960401)77:7<1395::AID-CNCR26>3.0.CO;2-W (- Case Report) [OPEN ACCESS]
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** Kerbl, R; Urban, CE; Ladenstein, R; Schnellauf, C; Sitzwohl, C; Lackner, H; Gleispach, H; Fauler, G; Ambros, PF; Ambros, IM; Rumpler, S; Gadner, H; Spuller, E; Höfler, G; Amann, G; Kytir, J; Mutz, I 5 years neuroblastoma screening in Austria: rate of participation, results and a comparison with other screening areas
Wien Klin Wochenschr. 1996; 108(13):398-403
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** Ladenstein, R; Ambros, PF; Urban, C; Ambros, IM; Fink, FM; Zoubek, A; Grienberger, H; Schmitt, K; Kerbl, R; Horcher, E; Amann, G; Höfler, G; Heinzl, H; Gadner, H; Mutz, I Value of prognostic factors in the Austrian A-NB87 Neuroblastoma Study
Klin Padiatr. 1996; 208(4):210-220 Doi: 10.1055/s-2008-1046476
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** Lipp, RW; Sill, H; Aigner, R; Ranner, G; Hoefler, G; Passath, A; Leb, G Gallium-67-citrate scintigraphy of high-grade T-cell non-Hodgkin's lymphoma.
J NUCL MED 1996 37: 1524-1525. (- Case Report) [OPEN ACCESS]
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** Wolf, P; Müllegger, R; Cerroni, L; Aigner, R; Fueger, G; Höfler, G; Derbaschnig, J; Kerl, H Photoaccentuated erythroderma associated with CD4+ T lymphocytopenia: successful treatment with 5-methoxypsoralen and UVA, interferon alfa-2b, and extracorporeal photopheresis.
J Am Acad Dermatol. 1996; 35(2 Pt 2):291-294 Doi: 10.1016%2FS0190-9622%2896%2990651-9 (- Case Report)
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Short report/Letter

** Neumeister, P; Linkesch, W; Höfler, G; Sill, H 2-Chlorodeoxyadenosine as first-line treatment in bronchus-associated lymphoid tissue lymphoma.
Blood. 1996; 87(8):3526-3526 Doi: 10.1182/blood.V87.8.3526a.bloodjournal8783526a (- Case Report) [OPEN ACCESS]
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** Schmidt, HH; Höfler, G; Beham-Schmid, C; Sill, H; Linkesch, W Bone marrow granulomas in hairy cell leukaemia.
Histopathology. 1996; 29(3):291-292 Doi: 10.1111/j.1365-2559.1996.tb01409.x
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** Trinker, M; Hófler, G; Sill, H False-positive diagnosis of tuberculosis with PCR.
Lancet. 1996; 348(9038):1388-1388 Doi: 10.1016/S0140-6736(05)65458-X (- Case Report)
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Review

** Bauernhofer, T; Stöger, H; Schmid, M; Smola, M; Gürtl-Lackner, B; Höfler, G; Ranner, G; Reisinger, E; Samonigg, H Sequential treatment of recurrent mesenteric desmoid tumor.
Cancer. 1996; 77(6):1061-1065 Doi: 10.1002/(SICI)1097-0142(19960315)77:6<1061::AID-CNCR9>3.0.CO;2-K (- Case Report) [OPEN ACCESS]
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Abstract (Journal)

** Fickert, P; Ramschak, H; Kenner, L; Hoefler, G; Hinterleitner, TA; Petritsch, W; Klimpfinger, M; Krejs, GJ; Stauber, RE Acute Budd Chiari syndrome with fulminant hepatic failure in a pregnant woman with factor V Leiden mutation.
HEPATOLOGY 1996 24: 1534-1534.
Web of Science

 

** Lax, S; Hofler, G; Zatloukal, K; Langsteger, W; Semlitsch, G; Eber, O Mutations in the thyrotropin receptor gene in hyperfunctioning thyroid nodules do not correlate with morphology
LAB INVEST 1996 74: 274-274.
Web of Science

 

** Neumeister, P; Hofler, G; BehamSchmid, C; Schmidt, H; Apfelbeck, U; Linkesch, W; Sill, H Homozygous deletions of the p16 gene in high-grade gastric malt lymphomas.
BLOOD 1996 88: 3311-3311.
Web of Science

 

1995

Full paper/article (Journal)

** Greinix, HT; Beham-Schmid, C; Silly, H; Hoefler, G; Kasparek, A; Seewann, HL Heavy-chain immunoglobulin gene rearrangement and cytoplasmic immunoglobulin expression in acute monocytic leukemia following primary germ cell tumor.
Ann Hematol. 1995; 70(2):109-112 Doi: 10.1007/BF01834391 (- Case Report)
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** Ladenstein, R; Urban, C; Gadner, H; Fink, FM; Zoubek, A; Emminger, W; Grienberger, H; Schmitt, K; Ambros, PF; Ambros, IM; HORCHER, E; AMANN, G; HOFLER, G; KERBEL, R; MUTZ, I First experience with prognostic factors in unselected neuroblastoma patients. The Austrian Neuroblastoma 87 Study.
EUR J CANCER. 1995; 31A(4): 637-641. Doi: 10.1016/0959-8049(95)00069-U
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** Levak-Frank, S; Radner, H; Walsh, A; Stollberger, R; Knipping, G; Hoefler, G; Sattler, W; Weinstock, PH; Breslow, JL; Zechner, R Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice.
J Clin Invest. 1995; 96(2):976-986 Doi: 10.1172/JCI118145 [OPEN ACCESS]
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** Malle, E; Oettl, K; Sattler, W; Hoefler, G; Kostner, GM Cholesterol biosynthesis in dermal fibroblasts from patients with metabolic disorders of peroxisomal origin.
Eur J Clin Invest. 1995; 25(1):59-67 Doi: 10.1111/j.1365-2362.1995.tb01527.x [OPEN ACCESS]
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** Semlitsch, G; Höfler, G; Langsteger, W; Lax, S; Zatloukal, K; Berger, A; Eber, O TSH receptor double mutation in functional autonomic thyroid nodule
Acta Med Austriaca. 1995; 22(4):75-77
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** Sill, H; Höfler, G; Kaufmann, P; Horina, J; Spuller, E; Kleinert, R; Beham-Schmid, C Angiotropic large cell lymphoma presenting as thrombotic microangiopathy (thrombotic thrombocytopenic purpura).
Cancer. 1995; 75(5):1167-1170 Doi: 10.1002/1097-0142(19950301)75:5<1167::AID-CNCR2820750517>3.0.CO;2-1 (- Case Report) [OPEN ACCESS]
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** Trauner, M; Grasmug, E; Stauber, RE; Hammer, HF; Hoefler, G; Reisinger, EC Recurrent Salmonella enteritidis sepsis and hepatic tuberculosis.
Gut. 1995; 37(1):136-139 Doi: 10.1136/gut.37.1.136 (- Case Report) [OPEN ACCESS]
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** Wöckel, W; Höfler, G; Popper, HH; Morresi, A Lymphoepithelioma-like carcinoma of the lung.
Pathol Res Pract. 1995; 191(11):1170-1174 Doi: 10.1016/S0344-0338(11)80665-5 (- Case Report)
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Review

** Schmidt, HH; Sill, H; Eibl, M; Beham-Schmid, C; Höfler, G; Haas, OA; Krejs, GJ; Linkesch, W Hodgkin's disease developing after spontaneous remission of chronic lymphocytic leukemia.
Ann Hematol. 1995; 71(5):247-252 Doi: 10.1007/s002770050113 (- Case Report)
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Abstract (Journal)

** LEDET, S; HOEFLER, G; CONWAY, EJ; WINTER, E; HUDNALL, D; WOECKEL, W; CAGLE, PT; POPPER, HH DETECTION OF EPSTEIN-BARR-VIRUS IN INFLAMMATORY PSEUDOTUMOR OF THE LUNG BY POLYMERASE CHAIN-REACTION AND IN-SITU HYBRIDIZATION
LAB INVEST 1995 72: A149-A149.
Web of Science

 

** LEVAKFRANK, S; JURITSCH, B; HOEFLER, G; WALSH, AM; BRESLOW, JL; ZECHNER, R MYOPATHY AND PROLIFERATION OF MITOCHONDRIA AND PEROXISOMES CAUSED BY OVEREXPRESSION OF LIPOPROTEIN-LIPASE IN MUSCLE
CIRCULATION 1995 92: 3045-3045.
Web of Science

 

Note

** Schwinger, W; Urban, C; Mache, CJ; Resch, B; Lackner, H; Höfler, G; Beham-Schmid, C; Gilli, R; Wagner, K; Haas, OA Adoptive immunotransfer with viable donor mononuclear cells for recurrent chronic myelogenous leukemia after allogeneic bone marrow transplantation in two children.
Pediatr Hematol Oncol. 1995; 12(1):47-54 Doi: 10.3109/08880019509029527 (- Case Report)
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1994

Full paper/article (Journal)

** Hoefler, G; Forstner, M; McGuinness, MC; Hulla, W; Hiden, M; Krisper, P; Kenner, L; Ried, T; Lengauer, C; Zechner, R cDNA cloning of the human peroxisomal enoyl-CoA hydratase: 3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme and localization to chromosome 3q26.3-3q28: a free left Alu Arm is inserted in the 3' noncoding region.
GENOMICS. 1994; 19(1): 60-67. Doi: 10.1006%2Fgeno.1994.1013
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** Mache, CJ; Slavc, I; Schmid, C; Hoefler, G; Urban, CE; Schwinger, W; Winter, E; Hulla, W; Zenz, W; Holter, W Familial hemophagocytic lymphohistiocytosis associated with disseminated T-cell lymphoma: a report of two siblings.
Ann Hematol. 1994; 69(2):85-91 Doi: 10.1007/BF01698488 (- Case Report)
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** Popper, HH; el-Shabrawi, Y; Wöckel, W; Höfler, G; Kenner, L; Jüttner-Smolle, FM; Pongratz, MG Prognostic importance of human papilloma virus typing in squamous cell papilloma of the bronchus: comparison of in situ hybridization and the polymerase chain reaction.
Hum Pathol. 1994; 25(11):1191-1197 Doi: 10.1016/0046-8177(94)90036-1
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** Popper, HH; Winter, E; Höfler, G DNA of Mycobacterium tuberculosis in formalin-fixed, paraffin-embedded tissue in tuberculosis and sarcoidosis detected by polymerase chain reaction.
Am J Clin Pathol. 1994; 101(6):738-741 Doi: 10.1093/ajcp/101.6.738
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Note

** Kenner, L; el-Shabrawi, Y; Hutter, H; Forstner, M; Zatloukal, K; Hoefler, G; Preisegger, KH; Kurzbauer, R; Denk, H Expression of three- and four-repeat tau isoforms in mouse liver.
Hepatology. 1994; 20(4 Pt 1):1086-1089 Doi: 10.1002/hep.1840200442
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** Mandak, M; Kerbl, U; Kleinert, R; Höfler, G; Zeichen, R; Denk, H Miliary tuberculosis of the liver as a cause of septic shock with multi-organ failure
Wien Klin Wochenschr. 1994; 106(4):111-114 (- Case Report)
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** SPORK, E; SPORK, KD; MILLNER, MM; RANNER, G; PENKA, B; POPPER, HH; HOFLER, G PULMONARY AND CENTRAL-NERVOUS-SYSTEM TUBERCULOSIS IN AN INFANT
MONATSSCHR KINDERHEILK. 1994; 142(6): 406-408.
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1993

Short report/Letter

** Haubenwallner, S; Hörl, G; Shachter, NS; Presta, E; Fried, SK; Höfler, G; Kostner, GM; Breslow, JL; Zechner, R A novel missense mutation in the gene for lipoprotein lipase resulting in a highly conservative amino acid substitution (Asp180-->Glu) causes familial chylomicronemia (type I hyperlipoproteinemia).
GENOMICS. 1993; 18(2): 392-396. Doi: 10.1006/geno.1993.1481
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Note

** Malle, E; Leis, HJ; Steinmetz, A; Paschke, E; Hoefler, G Cyclooxygenase pathway in dermal fibroblasts from patients with metabolic disorders of peroxisomal origin.
CLIN CHIM ACTA. 1993; 217(2): 205-212. Doi: 10.1016/0009-8981(93)90167-3
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1992

Abstract (Journal)

** PREISEGGER, KH; KENNER, L; FORSTNER, M; HUTTER, H; HOEFLER, G; KURZBAUER, R; ZATLOUKAL, K; DENK, H FURTHER CHARACTERIZATION OF TAU-LIKE PROTEINS INVOLVED DURING HUMAN AND MURINE MALLORY BODY FORMATION
HEPATOLOGY. 1992; 16(4): A187-A187.
Web of Science

 

1991

Full paper/article (Journal)

** Chen, GL; Balfe, A; Erwa, W; Hoefler, G; Gaertner, J; Aikawa, J; Chen, WW Import of human bifunctional enzyme into peroxisomes of human hepatoma cells in vitro.
Biochem Biophys Res Commun. 1991; 178(3):1084-1091 Doi: 10.1016/0006-291X(91)91003-U
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** Hoefler, G; Paschke, E; Hoefler, S; Moser, AB; Moser, HW Photosensitized killing of cultured fibroblasts from patients with peroxisomal disorders due to pyrene fatty acid-mediated ultraviolet damage.
J Clin Invest. 1991; 88(6):1873-1879 Doi: 10.1172/JCI115509 [OPEN ACCESS]
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** Watkins, PA; Ferrell, EV; Pedersen, JI; Hoefler, G Peroxisomal fatty acid beta-oxidation in HepG2 cells.
Arch Biochem Biophys. 1991; 289(2): 329-336. Doi: 10.1016/0003-9861(91)90419-J
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1990

Full paper/article (Journal)

** Balfe, A; Hoefler, G; Chen, WW; Watkins, PA Aberrant subcellular localization of peroxisomal 3-ketoacyl-CoA thiolase in the Zellweger syndrome and rhizomelic chondrodysplasia punctata.
Pediatr Res. 1990; 27(3):304-310 Doi: 10.1203/00006450-199003000-00023 [OPEN ACCESS]
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1989

Full paper/article (Journal)

** ROSCHER, A; HOFLER, S; HOFLER, G; PASCHKE, E; PALTAUF, F; MOSER, A; MOSER, H GENETIC COMPLEMENTATION ANALYSIS IN PEROXISOMAL DISORDERS
J CLIN CHEM CLIN BIOCHEM. 1989; 27: 304-305.
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** Roscher, AA; Hoefler, S; Hoefler, G; Paschke, E; Paltauf, F; Moser, A; Moser, H Genetic and phenotypic heterogeneity in disorders of peroxisome biogenesis--a complementation study involving cell lines from 19 patients.
Pediatr Res. 1989; 26(1):67-72 Doi: 10.1203/00006450-198907000-00019 [OPEN ACCESS]
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** Watkins, PA; Chen, WW; Harris, CJ; Hoefler, G; Hoefler, S; Blake, DC; Balfe, A; Kelley, RI; Moser, AB; Beard, ME Peroxisomal bifunctional enzyme deficiency.
J Clin Invest. 1989; 83(3):771-777 Doi: 10.1172/JCI113956 (- Case Report) [OPEN ACCESS]
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1988

Full paper/article (Journal)

** Hoefler, G; Harnoncourt, F; Paschke, E; Mirtl, W; Pfeiffer, KH; Kostner, GM Lipoprotein Lp(a). A risk factor for myocardial infarction.
ARTERIOSCLEROSIS-J VASC BIOL. 1988; 8(4): 398-401. Doi: 10.1161/01.ATV.8.4.398 [OPEN ACCESS]
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** Hoefler, G; Hoefler, S; Watkins, PA; Chen, WW; Moser, A; Baldwin, V; McGillivary, B; Charrow, J; Friedman, JM; Rutledge, L Biochemical abnormalities in rhizomelic chondrodysplasia punctata.
J Pediatr. 1988; 112(5):726-733 Doi: 10.1016/S0022-3476(88)80689-9
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** Hoefler, S; Hoefler, G; Moser, AB; Watkins, PA; Chen, WW; Moser, HW Prenatal diagnosis of rhizomelic chondrodysplasia punctata.
Prenat Diagn. 1988; 8(8):571-576 Doi: 10.1002/pd.1970080804 (- Case Report)
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** Naidu, S; Hoefler, G; Watkins, PA; Chen, WW; Moser, AB; Hoefler, S; Rance, NE; Powers, JM; Beard, M; Green, WR Neonatal seizures and retardation in a girl with biochemical features of X-linked adrenoleukodystrophy: a possible new peroxisomal disease entity.
Neurology. 1988; 38(7):1100-1107 Doi: 10.1212/WNL.38.7.1100 (- Case Report)
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1987

Full paper/article (Journal)

** Paschke, E; Höfler, G; Roscher, A The effect of D-(+)-glucosamine on levels of free N-acetylneuraminic acid and UDP-N-acetylhexosamines in infantile sialic acid storage disease (ISSD) fibroblasts.
J Inherit Metab Dis. 1987; 10(1):48-51 Doi: 10.1007/BF01799487
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1986

Full paper/article (Journal)

** Paschke, E; Höfler, G; Roscher, A Infantile sialic acid storage disease: the fate of biosynthetically labeled N-acetyl-(3H)-neuraminic acid in cultured human fibroblasts.
Pediatr Res. 1986; 20(8):773-777 Doi: 10.1203/00006450-198608000-00015 [OPEN ACCESS]
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