Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Leis Hans-Joerg |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2023
Originalarbeit (Zeitschrift)
** Leis, HJ; Windischhofer, W
Phospholipase D1 activity is crucial for cytosolic phospholipase A2 -dependent prostaglandin E2 formation in murine osteoblastic MC3T3-E1 cells.
Prostaglandins Leukot Essent Fatty Acids. 2023; 198-199:102592
Doi: 10.1016/j.plefa.2023.102592
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2022
Originalarbeit (Zeitschrift)
** Fojnica, A; Leis, HJ; Murkovic, M
Identification and Characterization of the Stability of Hydrophobic Cyclolinopeptides From Flaxseed Oil
FRONT NUTR. 2022; 9: 903611
Doi: 10.3389/fnut.2022.903611
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2020
Originalarbeit (Zeitschrift)
** Raspotnig, G; Anderl, F; Kunert, O; Schaider, M; Brückner, A; Schubert, M; Dötterl, S; Fuchs, R; Leis, HJ
A Novel Class of Defensive Compounds in Harvestmen: Hydroxy-γ-Lactones from the Phalangiid Egaenus convexus.
J Nat Prod. 2020; 83(11):3278-3286
Doi: 10.1021/acs.jnatprod.0c00277
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2018
Originalarbeit (Zeitschrift)
** Schaider, M; Novak, T; Komposch, C; Leis, HJ; Raspotnig, G
Methyl-ketones in the scent glands of Opiliones: a chemical trait of cyphophthalmi retrieved in the dyspnoan Nemastoma triste.
CHEMOECOLOGY. 2018; 28(2): 61-67.
Doi: 10.1007/s00049-018-0257-5
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2016
Originalarbeit (Zeitschrift)
** Bodner, M; Vagalinski, B; Makarov, SE; Antić, DŽ; Vujisić, LV; Leis, HJ; Raspotnig, G
"Quinone Millipedes" Reconsidered: Evidence for a Mosaic-Like Taxonomic Distribution of Phenol-Based Secretions across the Julidae.
J Chem Ecol. 2016; 42(3):249-258
Doi: 10.1007/s10886-016-0680-4
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** Leis, HJ; Windischhofer, W
Ionomycin induces prostaglandin E2 formation in murine osteoblastic MC3T3-E1 cells via mechanisms independent of its ionophoric nature.
Biochem Cell Biol. 2016; 94(3):236-240
Doi: 10.1139/bcb-2015-0148
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** Leis, HJ; Windischhofer, W
Potentiation of endothelin-1-induced prostaglandin E2 formation by Ni(2+) and Sr(2+) in murine osteoblastic MC3T3-E1 cells.
J Trace Elem Med Biol. 2016; 33(3):81-86
Doi: 10.1016/j.jtemb.2015.10.001
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** Leis, HJ; Windischhofer, W
Calcium-independent phospholipases A2 in murine osteoblastic cells and their inhibition by bromoenol lactone: impact on arachidonate dynamics and prostaglandin synthesis.
J Enzyme Inhib Med Chem. 2016; 31(6):1203-1213
Doi: 10.3109/14756366.2015.1114929
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2015
Originalarbeit (Zeitschrift)
** Brückner, A; Stabentheiner, E; Leis, HJ; Raspotnig, G
Chemical basis of unwettability in Liacaridae (Acari, Oribatida): specific variations of a cuticular acid/ester-based system.
Exp Appl Acarol. 2015; 66(3):313-335
Doi: 10.1007/s10493-015-9914-3
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** Leis, HJ; Windischhofer, W
Molecular characterisation of group IVA (cytosolic) phospholipase A2 in murine osteoblastic MC3T3-E1 cells.
Protein J. 2015; 34(1):29-34
Doi: 10.1007/s10930-014-9594-6
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** Schlagenhauf, A; Haidl, H; Leschnik, B; Leis, HJ; Heinemann, A; Muntean, W
Prostaglandin E2 levels and platelet function are different in cord blood compared to adults.
Thromb Haemost. 2015; 113(1):97-106
Doi: 10.1160/TH14-03-0218
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2014
Originalarbeit (Zeitschrift)
** Leis, HJ; Fauler, G; Windischhofer, W
Enantioselective quantitative analysis of amphetamine in human plasma by liquid chromatography/high-resolution mass spectrometry.
Anal Bioanal Chem. 2014; 406(18):4473-4480
Doi: 10.1007/s00216-014-7850-4
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** Raspotnig, G; Schaider, M; Stabentheiner, E; Leis, HJ; Karaman, I
On the enigmatic scent glands of dyspnoan harvestmen (Arachnida, Opiliones): first evidence for the production of volatile secretions.
Chemoecology. 2014; 24(2):43-55
Doi: 10.1007/s00049-014-0146-5
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2012
Originalarbeit (Zeitschrift)
** Leis, HJ; Donnarumma, F; Wintersteiger, R; Lazarus, R; Braml, B; Ortner, A; Windischhofer, W
Bis-pentafluorobenzyl derivatives of N-acetyl-l-methionine and N-acetyl-l-selenomethionine for the quantitative determination in human plasma by gas chromatography-negative ion chemical ionisation mass spectrometry.
J Chromatogr A. 2012; 1242(9):92-100
Doi: 10.1016/j.chroma.2012.04.028
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** Leis, HJ; Windischhofer, W
Quantitative method for determination of amphetamine in plasma using negative ion chemical ionisation GC-MS of o-(pentafluorobenzyloxycarbonyl)-benzoyl derivatives.
J Sep Sci. 2012; 35(16):2095-2100
Doi: 10.1002/jssc.201200082
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** Leis, HJ; Windischhofer, W
(S)-(-)-N-(pentafluorobenzylcarbamoyl)prolyl chloride: a chiral derivatisation reagent designed for gas chromatography/negative ion chemical ionisation mass spectrometry of amino compounds.
Rapid Commun Mass Spectrom. 2012; 26(6):592-598
Doi: 10.1002/rcm.6146
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** Leis, HJ; Windischhofer, W
Quantitative determination of amphetamine in plasma using negative ion chemical ionization GC-MS of o-(pentafluorobenzyl-oxycarbonyl)-2,3,4,5-tetrafluorobenzoyl derivatives.
J Sep Sci. 2012; 35(23):3326-3331
Doi: 10.1002/jssc.201200579
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** Leis, HJ; Windischhofer, W;
Determination of memantine in human plasma by GC using negative ion chemical ionization MS detection after derivatization with a new reagent.
MICROCHIM ACTA. 2012; 178(3-4): 309-314.
Doi: 10.1007/s00604-012-0840-3
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** Leis, HJ; Windischhofer, W;
Quantitative determination of memantine in human plasma by GC using negative ion chemical ionization MS detection after derivatization with a new reagent, o-(pentafluorobenzyloxycarbonyl)-2,3,4,5-tetrafluorobenzoyl chloride.
MICROCHIM ACTA. 2012; 179(3-4): 249-255.
Doi: 10.1007/s00604-012-0886-2
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** Ullen, A; Fauler, G; Bernhart, E; Nusshold, C; Reicher, H; Leis, HJ; Malle, E; Sattler, W
Phloretin ameliorates 2-chlorohexadecanal-mediated brain microvascular endothelial cell dysfunction in vitro.
Free Radic Biol Med. 2012; 53(9):1770-1781
Doi: 10.1016/j.freeradbiomed.2012.08.575
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** Windischhofer, W; Huber, E; Rossmann, C; Semlitsch, M; Kitz, K; Rauh, A; Devaney, T; Leis, HJ; Malle, E
LPA-induced suppression of periostin in human osteosarcoma cells is mediated by the LPA(1)/Egr-1 axis.
Biochimie. 2012; 94(9):1997-2005
Doi: 10.1016/j.biochi.2012.05.023
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2011
Originalarbeit (Zeitschrift)
** Kitz, K; Windischhofer, W; Leis, HJ; Huber, E; Kollroser, M; Malle, E
15-Deoxy-Δ12,14-prostaglandin J2 induces Cox-2 expression in human osteosarcoma cells through MAPK and EGFR activation involving reactive oxygen species.
Free Radic Biol Med. 2011; 50(7):854-865
Doi: 10.1016/j.freeradbiomed.2010.12.039
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** Leis, HJ; Schütz, H; Windischhofer, W
Quantitative determination of methylphenidate in plasma by gas chromatography negative ion chemical ionisation mass spectrometry using o-(pentafluorobenzyloxycarbonyl)-benzoyl derivatives.
Anal Bioanal Chem. 2011; 400(8):2663-2670
Doi: 10.1007/s00216-011-5048-6
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** Leis, HJ; Windischhofer, W
Gas chromatography-negative ion chemical ionisation mass spectrometry using o-(pentafluorobenzyloxycarbonyl)-2,3,4,5-tetrafluorobenzoyl derivatives for the quantitative determination of methylphenidate in human plasma.
J Chromatogr B Analyt Technol Biomed Life Sci. 2011; 879(23): 2299-2303.
Doi: 10.1016/j.jchromb.2011.06.017
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** Leis, HJ; Windischhofer, W
A versatile electrophoric derivatisation reagent for negative ion chemical ionisation mass spectrometry: o-(pentafluorobenzyloxycarbonyl)-2,3,4,5-tetrafluorobenzoyl chloride.
Anal Bioanal Chem. 2011; 400(8): 2623-2630.
Doi: 10.1007/s00216-010-4583-x
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** Raspotnig, G; Leutgeb, V; Krisper, G; Leis, HJ
Discrimination of Oribotritia species by oil gland chemistry (Acari, Oribatida).
Exp Appl Acarol. 2011; 54(3):211-224
Doi: 10.1007/s10493-011-9434-8
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Korrektur
** Ullen, A; Fauler, G; Kofeler, H; Waltl, S; Nusshold, C; Bernhart, E; Reicher, H; Leis, HJ; Wintersperger, A; Malle, E; Sattler, W
Mouse brain plasmalogens are targets for hypochlorous acid-mediated modification in vitro and in vivo (vol 49, pg 1655, 2010)
FREE RADICAL BIOL MED. 2011; 50(7): 903-903.
Doi: 10.1016/j.freeradbiomed.2011.01.008
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Abstract (Zeitschrift)
** Donnarumma, F; Greilberger, J; Matzi, V; Lindenmann, J; Maier, A; Leis, HJ; Wintersteiger, R
Pharmacokinetic evaluation of a novel anti-cancer drug
INT J CLIN PHARM. 2011; 33(2):320-320.
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2010
Originalarbeit (Zeitschrift)
** Leis, HJ; Windischhofer, W
o-(Pentafluorobenzyloxycarbonyl)benzoyl chloride: a novel electrophoric derivatisation reagent for amino compounds designed for negative ion chemical ionisation mass spectrometry.
Rapid Commun Mass Spectrom. 2010; 24(22): 3320-3324.
Doi: 10.1002/rcm.4775
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** Ullen, A; Fauler, G; Köfeler, H; Waltl, S; Nusshold, C; Bernhart, E; Reicher, H; Leis, HJ; Wintersperger, A; Malle, E; Sattler, W
Mouse brain plasmalogens are targets for hypochlorous acid-mediated modification in vitro and in vivo.
Free Radic Biol Med. 2010; 49(11):1655-1665
Doi: 10.1016/j.freeradbiomed.2010.08.025
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** Wagner, BM; Donnarumma, F; Wintersteiger, R; Windischhofer, W; Leis, HJ
Simultaneous quantitative determination of alpha-ketoglutaric acid and 5-hydroxymethylfurfural in human plasma by gas chromatography-mass spectrometry.
Anal Bioanal Chem. 2010; 396(7): 2629-2637.
Doi: 10.1007/s00216-010-3479-0
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Abstract (Zeitschrift)
** Leis, H; Windischhofer, W
Molecular and functional characterization of group VI calcium-independent phospholipases in osteoblast-like MC3T3-E1 cells
BONE. 2010; 46: 116
Doi: 10.1016/j.bone.2010.01.119
[Poster]
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2009
Originalarbeit (Zeitschrift)
** Raspotnig, G; Leis, HJ
Wearing a raincoat: exocrine secretions contain anti-wetting agents in the oribatid mite, Liacarus subterraneus (Acari: Oribatida).
Exp Appl Acarol. 2009; 47(3):179-190
Doi: 10.1007/s10493-008-9212-4
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** Raspotnig, G; Stabentheiner, E; Fottinger, P; Schaider, M; Krisper, G; Rechberger, G; Leis, HJ
Opisthonotal glands in the Camisiidae (Acari, Oribatida): evidence for a regressive evolutionary trend
J ZOOL SYST EVOL RES. 2009; 47(1): 77-87.
Doi: 10.1111/j.1439-0469.2008.00486.x
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** Schütz, H; Fischer, R; Grossmann, M; Mazur, D; Leis, HJ; Ammer, R
Lack of bioequivalence between two methylphenidate extended modified release formulations in healthy volunteers.
Int J Clin Pharmacol Ther. 2009; 47(12): 761-769.
Doi: 10.5414/CPP47761
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Abstract (Zeitschrift)
** Kitz, K; Malle, E; Leis, HJ; Windischhofer, W
15-Deoxy-Delta(12,14)-prostaglandin J(2) induces Cox-2 expression and ROS-dependent apoptosis in human osteosarcoma cells
BONE. 2009; 45: S103-S104.
Doi: 10.1016/j.bone.2009.04.172
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** Kitz, K; Malle, E; Leis, HJ; Windischhofer, W
Peroxisome proliferator-activated receptor gamma agonists induce cyclooxygenase 2 expression and apoptosis in human osteosarcoma cells
BONE. 2009; 44(2):S285-S285.-European Symposium of Calcified Tissues; MAY 23-27, 2009; Vienna, AUSTRIA.
Doi: 10.1016/j.bone.2009.03.511
[Poster]
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2008
Originalarbeit (Zeitschrift)
** Leis, HJ; Windischhofer, W
Inhibition of cyclooxygenases 1 and 2 by the phospholipase-blocker, arachidonyl trifluoromethyl ketone.
Br J Pharmacol. 2008; 155(5): 731-737.
Doi: 10.1038/bjp.2008.304
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** Raspotnig, G; Kaiser, R; Stabentheiner, E; Leis, HJ
Chrysomelidial in the opisthonotal glands of the oribatid mite, Oribotritia berlesei.
J CHEM ECOL. 2008; 34(8): 1081-1088.
Doi: 10.1007/s10886-008-9508-1
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** Raspotnig, G; Krisper, G; Fauler, G; Leis, HJ
DISTINCTIVE CUTICULAR HYDROCARBON PROFILES IN ORIBATID MITES (ACARI: ORIBATIDA)
ANN ZOOL. 2008; 58(2): 445-452.
Doi: 10.3161/000345408X326771
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** Rauh, A; Windischhofer, W; Kovacevic, A; DeVaney, T; Huber, E; Semlitsch, M; Leis, HJ; Sattler, W; Malle, E
Endothelin (ET)-1 and ET-3 promote expression of c-fos and c-jun in human choriocarcinoma via ET(B) receptor-mediated G(i)- and G(q)-pathways and MAP kinase activation.
Br J Pharmacol. 2008; 154(1):13-24
Doi: 10.1038/bjp.2008.92
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2006
Originalarbeit (Zeitschrift)
** Fischer, R; Schütz, H; Grossmann, M; Leis, HJ; Ammer, R
Bioequivalence of a methylphenidate hydrochloride extended-release preparation: comparison of an intact capsule and an opened capsule sprinkled on applesauce.
INT J CLIN PHARM THERAPEUTICS. 2006; 44(3): 135-141.
Doi: 10.5414/CPP44135
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2005
Originalarbeit (Zeitschrift)
** Leis, HJ; Windischhofer, W
Quantitative determination of fluvastatin in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry using 18O2-fluvastatin as an internal standard.
RAPID COMMUN MASS SPECTROM. 2005; 19(2): 128-132.
Doi: 10.1002/rcm.1758
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** Raspotnig, G; Fauler, G; Leis, M; Leis, HJ
Chemical profiles of scent gland secretions in the cyphophthalmid opilionid harvestmen, Siro duricorius and S-exilis
J CHEM ECOL. 2005; 31: 1353-1368.
Doi: 10.1007/s10886-005-5291-4
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** Raspotnig, G; Krisper, G; Schuster, R; Fauler, G; Leis, HJ
Volatile exudates from the oribatid mite, Platynothrus peltifer.
J CHEM ECOL. 2005; 31(2): 419-430.
Doi: 10.1007%2Fs10886-005-1350-0
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2004
Originalarbeit (Zeitschrift)
** Leis, HJ; Fauler, G; Windischhofer, W
Synthesis of d1-N-ethyltramadol as an internal standard for the quantitative determination of tramadol in human plasma by gas chromatography-mass spectrometry.
J CHROMATOGR B. 2004; 804(2): 369-374.
Doi: 10.1016/j.jchromb.2004.01.045
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** Leis, HJ; Fauler, G; Windischhofer, W
Use of 18O3-clodronate as an internal standard for the quantitative analysis of clodronate in human plasma by gas chromatography/electron ionisation mass spectrometry.
RAPID COMMUN MASS SPECTROM. 2004; 18(23): 2781-2784.
Doi: 10.1002/rcm.1688
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Übersichtsarbeit
** Leis, HJ; Fauler, G; Rechberger, GN; Windischhofer, W
Electron-capture mass spectrometry: a powerful tool in biomedical trace level analysis.
CURR MEDICINAL CHEM. 2004; 11(12): 1585-1594.
Doi: 10.2174/0929867043365035
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2003
Originalarbeit (Zeitschrift)
** Jörg Leis, H; Windischhofer, W; Rechberger, GN; Fauler, G
Synthesis of (18)O(2)valproic acid and its use as an internal standard for the quantitative measurement by gas chromatography-electron ionization mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci. 2003; 784(1):69-75
Doi: 10.1016/S1570-0232(02)00755-9
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** Leis, HJ; Fauler, G; Rechberger, GN; Windischhofer, W
Quantitative trace analysis of estriol in human plasma by negative ion chemical ionization gas chromatography-mass spectrometry using a deuterated internal standard.
J Chromatogr B Analyt Technol Biomed Life Sci. 2003; 794(2):205-213
Doi: 10.1016/S157-0232(03)00454-9
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** Leis, HJ; Rechberger, GN; Fauler, G; Windischhofer, W
Enantioselective trace analysis of amphetamine in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry.
Rapid Commun Mass Spectrom. 2003; 17(6):569-575
Doi: 10.1002/rcm.949
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** Rechberger, GN; Fauler, G; Windischhofer, W; Köfeler, H; Erwa, W; Leis, HJ
Quantitative analysis of clindamycin in human plasma by liquid chromatography/electrospray ionisation tandem mass spectrometry using d1-N-ethylclindamycin as internal standard.
Rapid Commun Mass Spectrom. 2003; 17(2):135-139
Doi: 10.1002/rcm.887
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** Regittnig, W; Ellmerer, M; Fauler, G; Sendlhofer, G; Trajanoski, Z; Leis, HJ; Schaupp, L; Wach, P; Pieber, TR
Assessment of transcapillary glucose exchange in human skeletal muscle and adipose tissue.
Am J Physiol Endocrinol Metab. 2003; 285(2):E241-E251
Doi: 10.1152/ajpendo.00351.2002
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Abstract (Zeitschrift)
** Leis, HJ; Windischhofer, W; Fauler, G; Zach, D; Raspotnig, G
Disintegrins and osteoblastic Prostaglandin E-2 synthesis
BONE 2003 33: S16-S16.
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** Windischhofer, W; Zach, D; Fauler, G; Rechberger, GN; Leis, HJ
ET-1 induced expression of PGHS-2 in MC3T3-E1 osteoblast-like cells
BONE 2003 33: S16-S16.
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** Zach, D; Windischhofer, W; Rechberger, G; Fauler, G; Raspotnig, G; Kofeler, H; Leis, HJ
Endothelin A receptor-mediated calcium mobilization in a clonal murine osteoblast-like cell line, MC3T3-E1/B
BONE 2003 33: S16-S16.
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2002
Originalarbeit (Zeitschrift)
** Leis, HJ; Fauler, G; Raspotnig, G; Windischhofer, W
Quantitative gas chromatographic/mass spectrometric analysis of morphine glucuronides in human plasma by negative ion chemical ionization mass spectrometry.
J MASS SPECTROMETRY 2002 37: 395-400.
Doi: 10.1002/jms.294
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** Leis, HJ; Fauler, G; Windischhofer, W
Quantitative analysis of memantine in human plasma by gas chromatography/negative ion chemical ionization/mass spectrometry.
J MASS SPECTROMETRY 2002 37: 477-480.
Doi: 10.1002/jms.303
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** Leis, HJ; Windischhofer, W; Fauler, G
Gas chromatography/negative-ion chemical ionisation mass spectrometry for the quantitative analysis of morphine in human plasma using pentafluorobenzyl carbonate derivatives.
RAPID COMMUN MASS SPECTROM 2002 16: 646-649.
Doi: 10.1002/rcm.618
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** Leis, HJ; Windischhofer, W; Fauler, G
Improved sample preparation for the quantitative analysis of paroxetine in human plasma by stable isotope dilution negative ion chemical ionisation gas chromatography-mass spectrometry.
J CHROMATOGR B 2002 779: 353-357.
Doi: 10.1016/S1570-0232(02)00378-1
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** Windischhofer, W; Zach, D; Fauler, G; Raspotnig, G; Köfeler, H; Leis, HJ
Involvement of Rho and p38 MAPK in endothelin-1-induced expression of PGHS-2 mRNA in osteoblast-like cells.
J Bone Miner Res. 2002; 17(10):1774-1784
Doi: 10.1359/jbmr.2002.17.10.1774
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Abstract (Zeitschrift)
** Regittnig, W; Ellmerer, M; Fauler, G; Sendlhofer, G; Trajanoski, Z; Leis, HJ; Wach, P; Schaupp, L; Pieber, TR
Evaluation of transcapillary glucose exchange in human skeletal muscle and adipose tissue.
DIABETES. 2002; 51: A31-A31.- 62nd Scientific Sessions of the American Diabetes Association ; JUN 14-18, 2002; San Francisco, CA, USA.
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2001
Originalarbeit (Zeitschrift)
** Leis, HJ; Windischhofer, W; Raspotnig, G; Fauler, G
Stable isotope dilution negative ion chemical ionization gas chromatography-mass spectrometry for the quantitative analysis of paroxetine in human plasma.
J Mass Spectrom. 2001; 36(8):923-928
Doi: 10.1002/jms.194
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** Raspotnig, G; Schuster, R; Krisper, G; Fauler, G; Leis, HJ
Chemistry of the oil gland secretion of Collohmannia gigantea (Acari: Oribatida).
EXP APPL ACAROL 2001 25: 933-946.
Doi: 10.1023/A:1020634215709
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** Zach, D; Windischhofer, W; Leis, HJ
Endothelin- and sarafotoxin-induced receptor-mediated calcium mobilization in a clonal murine osteoblast-like cell line, MC3T3-E1/B.
Bone. 2001; 28(6):595-602
Doi: 10.1016%2FS8756-3282%2801%2900461-6
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2000
Originalarbeit (Zeitschrift)
** Bergt, C; Oettl, K; Keller, W; Andreae, F; Leis, HJ; Malle, E; Sattler, W
Reagent or myeloperoxidase-generated hypochlorite affects discrete regions in lipid-free and lipid-associated human apolipoprotein A-I.
Biochem J. 2000; 346 Pt 2(3):345-354
Doi: 10.1042%2F0264-6021%3A3460345
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** Köfeler, HC; Fauler, G; Windischhofer, W; Leis, HJ
Effect of cytochrome P-450 inhibitors econazole, bifonazole and clotrimazole on prostanoid formation.
Br J Pharmacol. 2000; 130(6):1241-1246
Doi: 10.1038/sj.bjp.0703427
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** Leis, HJ; Fauler, G; Raspotnig, G; Windischhofer, W
Quantitative analysis of morphine in human plasma by gas chromatography-negative ion chemical ionization mass spectrometry.
J Chromatogr B Biomed Sci Appl. 2000; 744(1):113-119
Doi: 10.1016%2FS0378-4347%2800%2900237-1
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** Leis, HJ; Fauler, G; Raspotnig, G; Windischhofer, W
Negative ion chemical ionization for the determination of methylphenidate in human plasma by stable isotope dilution gas chromatography/mass spectrometry.
J Mass Spectrom. 2000; 35(9):1100-1104
Doi: 10.1002/1096-9888(200009)35:9<1100::AID-JMS32>3.0.CO;2-9
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** Leis, HJ; Köfeler, H; Raspotnig, G; Zach, D; Fauler, G; Windischhofer, W
Effect of the aminosteroid U73122 on prostaglandin E(2) production in a murine clonal osteoblast-like cell line, MC3T3-E1.
Biochem Pharmacol. 2000; 60(7):899-904
Doi: 10.1016%2FS0006-2952%2800%2900401-9
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1999
Originalarbeit (Zeitschrift)
** Leis, HJ; Fauler, G; Raspotnig, G; Windischhofer, W
An improved method for the measurement of the angiotensin-converting enzyme inhibitor lisinopril in human plasma by stable isotope dilution gas chromatography/negative ion chemical ionization mass spectrometry.
Rapid Commun Mass Spectrom. 1999; 13(8):650-653
Doi: 10.1002/(SICI)1097-0231(19990430)13:8<650::AID-RCM536>3.0.CO;2-X10.1002/(SICI)1097-0231(19990430)13:8<650::AID-RCM536>3.0.CO;2-X
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** Raspotnig, G; Fauler, G; Jantscher, A; Windischhofer, W; Schachl, K; Leis, HJ
Colorimetric determination of cell numbers by Janus green staining.
Anal Biochem. 1999; 275(1):74-83
Doi: 10.1006/abio.1999.4309
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** Regittnig, W; Trajanoski, Z; Leis, HJ; Ellmerer, M; Wutte, A; Sendlhofer, G; Schaupp, L; Brunner, GA; Wach, P; Pieber, TR
Plasma and interstitial glucose dynamics after intravenous glucose injection: evaluation of the single-compartment glucose distribution assumption in the minimal models.
Diabetes. 1999; 48(5):1070-1081
Doi: 10.2337/diabetes.48.5.1070
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1998
Originalarbeit (Zeitschrift)
** Jerlich, A; Fabjan, JS; Tschabuschnig, S; Smirnova, AV; Horakova, L; Hayn, M; Auer, H; Guttenberger, H; Leis, HJ; Tatzber, F; Waeg, G; Schaur, RJ
Human low density lipoprotein as a target of hypochlorite generated by myeloperoxidase.
Free Radic Biol Med. 1998; 24(7-8):1139-1148
Doi: 10.1016/S0891-5849(97)00439-5
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** Leis, HJ; Fauler, G; Raspotnig, G; Windischhofer, W
Quantitative determination of the angiotensin-converting enzyme inhibitor lisinopril in human plasma by stable isotope dilution gas chromatography/negative ion chemical ionization mass spectrometry.
Rapid Commun Mass Spectrom. 1998; 12(21):1591-1594
Doi: 10.1002/(SICI)1097-0231(19981115)12:21<1591::AID-RCM368>3.0.CO;2-C
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** Leis, HJ; Zach, D; Huber, E; Windischhofer, W
Prostaglandin endoperoxide synthase-2 contributes to the endothelin/sarafotoxin-induced prostaglandin E2 synthesis in mouse osteoblastic cells (MC3T3-E1): evidence for a protein tyrosine kinase-signaling pathway and involvement of protein kinase C.
Endocrinology. 1998; 139(3):1268-1277
Doi: 10.1210%2Fen.139.3.1268
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** Raspotnig, G; Freitag, B; Kastberger, G; Windischhofer, W; Leis, HJ
5-Methyl-2-phenyl-2-hexenal in the scent gland secretion of male cave crickets, Troglophilus cavicola and T. neglectus (Ensifera: Rhaphidophoridae).
J Insect Physiol. 1998; 44(5-6):413-417
Doi: 10.1016/S0022-1910(98)00044-4
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Übersichtsarbeit
** Leis, HJ; Fauler, G; Windischhofer, W
Stable-Isotope Labeled Target Compounds - Preparation and Use as Internal Standards in Quantitative Mass-Spectrometry
CURR ORG CHEM 1998 2: 131-144.
Doi: 10.2174/1385272802666220127211934
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1997
Originalarbeit (Zeitschrift)
** Fauler, G; Leis, HJ; Huber, E; Schellauf, C; Kerbl, R; Urban, C; Gleispach, H
Determination of homovanillic acid and vanillylmandelic acid in neuroblastoma screening by stable isotope dilution GC-MS.
J Mass Spectrom. 1997; 32(5):507-514
Doi: 10.1002/(SICI)1096-9888(199705)32:5<507::AID-JMS503>3.0.CO;2-9
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** Leis, HJ; Hulla, W; Gruber, R; Huber, E; Zach, D; Gleispach, H; Windischhofer, W
Phenotypic heterogeneity of osteoblast-like MC3T3-E1 cells: changes of bradykinin-induced prostaglandin E2 production during osteoblast maturation.
J Bone Miner Res. 1997; 12(4):541-551
Doi: 10.1359/jbmr.1997.12.4.541
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** Malle, E; Bollmann, A; Steinmetz, A; Gemsa, D; Leis, HJ; Sattler, W
Serum amyloid A (SAA) protein enhances formation of cyclooxygenase metabolites of activated human monocytes.
FEBS Lett. 1997; 419(2-3):215-219
Doi: 10.1016%2FS0014-5793%2897%2901459-2
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** Windischhofer, W; Leis, HJ
3Hbradykinin receptor-binding, receptor-recycling, and receptor-internalization of the B2 bradykinin receptor in the murine osteoblast-like cell line MC3T3-E1.
J Bone Miner Res. 1997; 12(10):1615-1625
Doi: 10.1359/jbmr.1997.12.10.1615
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Abstract (Zeitschrift)
** Jerlich, A; Fabjan, JS; Tschabuschnig, S; Smirnova, AV; Horakova, L; Hayn, M; Haslinger, E; Guttenberger, H; Leis, HJ; Schaur, RJ
APO B-100 of LDL as target of myeloperoxidase generated HOCl
FASEB J 1997 11: A1432-A1432.
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1996
Originalarbeit (Zeitschrift)
** Fauler, G; Leis, HJ; Schalamon, J; Muntean, W; Gleispach, H
Method for the determination of vitamin K1(20) in human plasma by stable isotope dilution/gas chromatography/mass spectrometry.
J MASS SPECTROMETRY. 1996; 31: 655-660.
Doi: 10.1002/(SICI)1096-9888(199606)31:6<655::AID-JMS339>3.0.CO;2-T
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** Gleispach, H; Leis, HJ; Erk, C; Bulut, M
Mass-Spectrometry of Crown-Ethers
J INCLUSION PHENOM MOL RECOGN 1996 24: 163-173.
Doi: 10.1007/BF01053429
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** Leis, HJ; Gleispach, H; Windischhofer, W
Preparation of Deuterated Diclofenac for Use as an Internal Standard in Quantitative Measurement by Gas-Chromatography Negative-Ion Chemical-Ionization Mass-Spectrometry
RAPID COMMUN MASS SPECTROM 1996 10: 1605-1606.
Doi: 10.1002/(SICI)1097-0231(199610)10:13<1605::AID-RCM684>3.3.CO;2-G
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** Leis, HJ; Leis, M; Windischhofer, W
Stable isotope labelling and determination of ketroprofen in human plasma and urine by gas chromatography/negative ion chemical ionization mass spectrometry.
J Mass Spectrom. 1996; 31(5):486-492
Doi: 10.1002/(SICI)1096-9888(199605)31:5<486::AID-JMS321>3.0.CO;2-L
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** Leis, HJ; Raspotnig, G; Windischhofer, W; Gleispach, H
Gas-Chromatography Mass-Spectrometry in Life Sciences
J ANAL CHEM, ENGL TR 1996 51: 1116-1122.
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** Leis, HJ; Zach, D; Huber, E; Ziermann, L; Gleispach, H; Windischhofer, W
Inhibition of prostanoid formation in intact cells by 2,5-di-(tert-butyl)-1,4-benzohydroquinone, a blocker of Ca(2+)-ATPases.
Br J Pharmacol. 1996; 117(3):540-544
Doi: 10.1111/j.1476-5381.1996.tb15224.x
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1995
Originalarbeit (Zeitschrift)
** Gallistl, S; Muntean, W; Leis, HJ
Effects of heparin and hirudin on thrombin generation and platelet aggregation after intrinsic activation of platelet rich plasma.
Thromb Haemost. 1995; 74(4):1163-1168
Doi: 10.1055/s-0038-1649897
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** Gleispach, H; Huber, E; Fauler, G; Kerbl, R; Urban, C; Leis, HJ
Neuroblastoma screening: labeling of HVA and VMA for stable isotope dilution gas chromatography-mass spectrometry.
NUTRITION. 1995; 11(5 Suppl): 604-606.
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** Leis, HJ; Gleispach, H; Windischhofer, W
Stable-Isotope Labeling and Quantitative-Determination of Enalaprilate in Human Plasma by GC-Nici-MS
J MASS SPECTROMETRY. 1995; 30: 1447-1452.
Doi: 10.1002/jms.1190301010
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** Leis, HJ; Zach, D; Huber, E; Ziermann, L; Gleispach, H; Windischhofer, W
On the inhibition of prostanoid formation by SK&F 96365, a blocker of receptor-operated calcium entry.
Br J Pharmacol. 1995; 114(3):598-601
Doi: 10.1111/j.1476-5381.1995.tb17181.x
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** Malle, E; Ibovnik, A; Leis, HJ; Kostner, GM; Verhallen, PF; Sattler, W
Lysine modification of LDL or lipoprotein(a) by 4-hydroxynonenal or malondialdehyde decreases platelet serotonin secretion without affecting platelet aggregability and eicosanoid formation.
Arterioscler Thromb Vasc Biol. 1995; 15(3):377-384
Doi: 10.1161/01.ATV.15.3.377
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** Sattler, W; Leis, HJ; Kostner, GM; Malle, E
Quantification of 7-dehydrocholesterol in plasma and amniotic fluid by liquid chromatography/particle beam-mass spectrometry as a biochemical diagnostic marker for the Smith-Lemli-Opitz syndrome.
Rapid Commun Mass Spectrom. 1995; 9(13):1288-1292
Doi: 10.1002/rcm.1290091313
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** Klaushofer, K; Varga, F; Glantschnig, H; Fratzl-Zelman, N; Czerwenka, E; Leis, HJ; Koller, K; Peterlik, M
The regulatory role of thyroid hormones in bone cell growth and differentiation.
J Nutr. 1995; 125(7 Su): 1996S-12003.
Doi: 10.1093/jn/125.suppl_7.1996S
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1994
Originalarbeit (Zeitschrift)
** Gleispach, H; Leis, HJ; Windischhofer, W
Applications of Gas-Chromatography Mass-Spectrometry in Clinical-Chemistry
J CHROMATOGR A. 1994; 665: 155-162.
Doi: 10.1016/0021-9673(94)87043-8
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** Leis, HJ; Windischhofer, W; Wintersteiger, R
Quantitative measurement of amphetamine in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry using (2H5)amphetamine as internal standard.
Biol Mass Spectrom. 1994; 23(10):637-641
Doi: 10.1002/bms.1200231006
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** Leis, HJ; Zach, D; Huber, E; Ziermann, L; Gleispach, H; Windischhofer, W
Extracellular Ca2+ sensing by the osteoblast-like cell line, MC3T3-E1.
Cell Calcium. 1994; 15(6):447-456
Doi: 10.1016%2F0143-4160%2894%2990109-0
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1993
Kurzbericht/Note
** Gleispach, H; Leis, HJ; Windischhofer, W; Muntean, W
A Contribution to the Measurement of Vitamin-K1(20) by Mass-Spectrometry
HRC, J HIGH RES CHROMATOGR. 1993; 16: 738-740.
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** Malle, E; Leis, HJ; Steinmetz, A; Paschke, E; Hoefler, G
Cyclooxygenase pathway in dermal fibroblasts from patients with metabolic disorders of peroxisomal origin.
CLIN CHIM ACTA. 1993; 217(2): 205-212.
Doi: 10.1016/0009-8981(93)90167-3
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1992
Kurzbericht/Note
** Leis, HJ; Ozand, PT; al Odaib, A; Gleispach, H
Quantitative measurement of N-acetyl-L-aspartic acid in urine by gas chromatography with negative-ion chemical ionization mass spectrometry.
J Chromatogr. 1992; 578(1):116-119
Doi: 10.1016/0378-4347(92)80232-F
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1991
Originalarbeit (Zeitschrift)
** Leis, HJ; Malle, E
Deuterium-labelling and quantitative measurement of ketotifen in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry.
Biol Mass Spectrom. 1991; 20(8):467-470
Doi: 10.1002/bms.1200200806
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** Malle, E; Sattler, W; Prenner, E; Leis, HJ; Hermetter, A; Gries, A; Kostner, GM
Effects of dietary fish oil supplementation on platelet aggregability and platelet membrane fluidity in normolipemic subjects with and without high plasma Lp(a) concentrations.
Atherosclerosis. 1991; 88(2-3):193-201
Doi: 10.1016/0021-9150(91)90081-D
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** Malle, E; Sattler, W; Prenner, E; Leis, HJ; Karàdi, I; Knipping, G; Romics, L; Kostner, GM
Platelet membrane fluidity in type IIA, type IIB and type IV hyperlipoproteinemia.
Atherosclerosis. 1991; 87(2-3):159-167
Doi: 10.1016/0021-9150(91)90018-X
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** Zwergel, U; Zwergel, T; Leis, HJ; Gleispach, H; Alexandridis, T; Belletz, M; Kirsten, R
Eicosanoid synthesis in the isolated human renal pelvis, ureter and bladder.
Br J Urol. 1991; 67(3):246-250
Doi: 10.1111/j.1464-410X.1991.tb15127.x
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Kurzbericht/Letter
** Ozand, PT; Feryal, RR; Gascon, GG; Gleispach, H; al Aqeel, A; Cook, JD; Nester, MJ; al Odaib, A; Leis, HJ
Prenatal detection of Canavan disease.
Lancet. 1991; 337(8743):735-736
Doi: 10.1016/0140-6736(91)90323-H
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1990
Originalarbeit (Zeitschrift)
** Leis, HJ; Gleispach, H; Nitsche, V; Malle, E
Quantitative determination of terbutaline and orciprenaline in human plasma by gas chromatography/negative ion chemical ionization/mass spectrometry.
Biomed Environ Mass Spectrom. 1990; 19(6):382-386
Doi: 10.1002/bms.1200190609
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** Leis, HJ; Leis, M; Welz, W; Malle, E
Determination of captopril in human blood by gas chromatography-negative-ion chemical ionization mass spectrometry with 18O4captopril as internal standard.
J Chromatogr. 1990; 529(2):299-308
Doi: 10.1016/S0378-4347(00)83836-0
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** Leis, HJ; Malle, E; Hoffmann, O; Klaushofer, K; Fratzl-Zelman, N; Koller, K; Peterlik, M
Experimental considerations on the measurement of prostaglandins during long-time incubations of neonatal mouse calvaria.
Biochem Biophys Res Commun. 1990; 169(2):545-550
Doi: 10.1016/0006-291X(90)90365-T
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** MALLE, E; STADLBAUER, W; OSTERMANN, G; HOFMANN, B; LEIS, HJ; KOSTNER, GM
ORGANIC AZIDES IN HETEROCYCLIC SYNTHESIS .10. SYNTHESIS OF NEW 2-SUBSTITUTED, 3-SUBSTITUTED, AND 4-SUBSTITUTED AZIDOQUINOLINES - INHIBITORS OF HUMAN BLOOD-PLATELET AGGREGATION INVITRO
EUR J MED CHEM. 1990; 25: 137-142.
Doi: 10.1016/0223-5234(90)90022-U
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** Welz, W; Sattler, W; Leis, HJ; Malle, E
Rapid analysis of non-esterified fatty acids as methyl esters from different biological specimens by gas chromatography after one-step esterification.
J Chromatogr. 1990; 526(2):319-329
Doi: 10.1016/S0378-4347(00)82516-5
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Kurzbericht/Note
** Leis, HJ; Welz, W; Malle, E
11-Dehydrothromboxane B2: convenient preparation of its stable isotope-labelled analogue for use in quantitative gas chromatography-mass spectrometry.
J CHROMATOGR-BIOMED APPL. 1990; 526(1): 169-173.
Doi: 10.1016/S0378-4347(00)82494-9
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** MALLE, E; NIMPF, J; LEIS, HJ; WURM, H; KOSTNER, GM
POSTPRANDIAL HYPERLIPEMIA AND PLATELET EICOSANOID METABOLISM
KLIN WOCHENSCHR. 1990; 68: 116-116.
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1989
Originalarbeit (Zeitschrift)
** Klaushofer, K; Hoffmann, O; Gleispach, H; Leis, HJ; Czerwenka, E; Koller, K; Peterlik, M
Bone-resorbing activity of thyroid hormones is related to prostaglandin production in cultured neonatal mouse calvaria.
J Bone Miner Res. 1989; 4(3):305-312
Doi: 10.1002/jbmr.5650040304
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** Klaushofer, K; Hoffmann, O; Hörandner, H; Karasegh, S; Fratzl-Zelman, N; Leis, HJ; Gleispach, H; Koller, K; Peterlik, M
Effect of auranofin on resorption, prostaglandin synthesis and ultrastructure of bone cells in cultured mouse calvaria.
J Rheumatol. 1989; 16(6):749-756
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** Malle, E; Gleispach, H; Kostner, GM; Leis, HJ
Isotope dilution gas chromatography-mass spectrometry for the study of eicosanoid metabolism in human blood platelets.
J Chromatogr. 1989; 488(1):283-293
Doi: 10.1016/S0378-4347(00)82953-9
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Kurzbericht/Note
** Leis, HJ; Gleispach, H
Characterization of the antidiarrhoeal loperamide by gas chromatography-mass spectrometry and application of the Hofmann degradation and Cope elimination reaction.
J Chromatogr. 1989; 494(4):324-330
Doi: 10.1016/S0378-4347(00)82683-3
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1988
Originalarbeit (Zeitschrift)
** Klaushofer, K; Hoffmann, O; Czerwenka, E; Leis, HJ; Gleispach, H; Koller, K; Peterlik, M
Comparison of the inhibitory effect of nonsteroidal antiinflammatory drugs on bone prostaglandin synthesis and resorption.
J Rheumatol. 1988; 15(3):486-491
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** Leis, HJ; Gleispach, H; Malle, E
A convenient route to stable-isotope-labelled compounds for use in quantitative gas chromatography/mass spectrometry.
Rapid Commun Mass Spectrom. 1988; 2(12): 263-265.
Doi: 10.1002/rcm.1290021202
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** Leis, HJ; Gleispach, H; Malle, E; Nitsche, V
Femtomole analysis of diclofenac in human plasma by gas chromatography/negative ion chemical ionization/mass spectrometry using (18O2)diclofenac as internal standard.
BIOMED ENVIRON MASS SPECTROM. 1988; 17(4): 307-310.
Doi: 10.1002/bms.1200170414
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** Leis, HJ; Gleispach, H; Nitsche, V; Malle, E
Femtomole analysis of diclofenac in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry using (18O2) diclofenac as internal standard.
BIOMED ENVIRON MASS SPECTROM. 1988; 17(6): 437-441.
Doi: 10.1002/bms.1200170604
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Abstract (Zeitschrift)
** GLEISPACH, H; MALLE, E; LEIS, HJ
ISOTOPE-DILUTION GAS CHROMATOGRAPHY-MASS SPECTROMETRY FOR THE STUDY OF THE EICOSANOID METABOLISM
ANN BIOL CLIN PARIS. 1988; 46(7): 505-505.
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** GLEISPACH, H; MALLE, E; LEIS, HJ
ISOTOPE-DILUTION GAS CHROMATOGRAPHY-MASS SPECTROMETRY FOR THE STUDY OF THE EICOSANOID METABOLISM
ANN BIOL CLIN PARIS. 1988; 46(7): 504-504.
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1987
Originalarbeit (Zeitschrift)
** Hoffmann, O; Klaushofer, K; Gleispach, H; Leis, HJ; Luger, T; Koller, K; Peterlik, M
Gamma interferon inhibits basal and interleukin 1-induced prostaglandin production and bone resorption in neonatal mouse calvaria.
Biochem Biophys Res Commun. 1987; 143(1):38-43
Doi: 10.1016/0006-291X(87)90626-7
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** Leis, HJ; Hohenester, E; Gleispach, H; Malle, E; Mayer, B
Measurement of prostaglandins, thromboxanes and hydroxy fatty acids by stable isotope dilution gas chromatography/mass spectrometry.
Biomed Environ Mass Spectrom. 1987; 14(11):617-621
Doi: 10.1002/bms.1200141108
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** Leis, HJ; Malle, E; Mayer, B; Kostner, GM; Esterbauer, H; Gleispach, H
Quantitative measurement of 5-, 12-, and 15-hydroxyeicosatetraenoic acid together with 12-hydroxyheptadecatrienoic acid by stable isotope dilution gas chromatography-negative ion chemical ionization-mass spectrometry.
Anal Biochem. 1987; 162(2):337-344
Doi: 10.1016/0003-2697(87)90401-5
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** Malle, E; Leis, HJ; Palm, W
Comparative studies on partial microsequence-analysis of Bence-Jones proteins.
Int J Biochem. 1987; 19(9):853-856
Doi: 10.1016/0020-711X(87)90245-X
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** Malle, E; Nimpf, J; Leis, HJ; Wurm, H; Gleispach, H; Kostner, GM
Cyclooxygenase and lipoxygenase metabolites during platelet aggregation: quantitative measurement by negative ion chemical ionization--gas chromatography/mass spectrometry.
Prostaglandins Leukot Med. 1987; 27(1):53-70
Doi: 10.1016/0262-1746(87)90059-X
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Übersichtsarbeit
** Malle, E; Leis, HJ; Karádi, I; Kostner, GM
Lipoxygenases and hydroperoxy/hydroxy-eicosatetraenoic acid formation.
Int J Biochem. 1987; 19(11):1013-1022
Doi: 10.1016/0020-711X(87)90301-6
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1986
Originalarbeit (Zeitschrift)
** LEIS, HJ; MALLE, E; MOSER, R; NIMPF, J; KOSTNER, GM; ESTERBAUER, H; GLEISPACH, H
Preparation of 18O-labelled standards of hydroxy-eicosatetraenoic acids and thromboxanes for quantitative measurement by gas chromatography/mass spectrometry.
Biomed Environ Mass Spectrom. 1986; 13(9):483-488
Doi: 10.1002/bms.1200130906
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Kurzbericht/Note
** Mayer, B; Moser, R; Leis, HJ; Gleispach, H
Rapid separation of arachidonic acid metabolites by silicic acid chromatography for subsequent quantitative analysis by gas chromatography-mass spectrometry.
J Chromatogr. 1986; 378(2):430-436
Doi: 10.1016/S0378-4347(00)80738-0
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1985
Originalarbeit (Zeitschrift)
** GLEISPACH, H; MOSER, R; LEIS, HJ
DETERMINATION OF ARACHIDONIC-ACID METABOLITES BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY
ANN BIOL CLIN PARIS. 1985; 43: 480-483.
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** Gleispach, H; Moser, R; Mayer, B; Esterbauer, H; Skriletz, U; Zierman, L; Leis, HJ
Qualitative and quantitative measurement of hydroxy fatty acids, thromboxanes and prostaglandins using stable isotope dilutions and detection by gas chromatography-mass spectrometry.
J Chromatogr. 1985; 344:11-21
Doi: 10.1016/S0378-4347(00)82002-2
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Kurzbericht/Letter
** GLEISPACH, H; MOSER, R; LEIS, HJ
CONTRIBUTION TO THE MEASUREMENT OF PROSTAGLANDINS BY GAS-CHROMATOGRAPHY MASS-SPECTROMETRY
J CHROMATOGR. 1985; 342: 245-246.
Doi: 10.1016/S0378-4347(00)84512-0
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