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Malle Ernst |

** = Publications listed in SCI/SSCI/Pubmed

2025

Full paper/article (Journal)

** Kalinová, K; Gottschalk, B; Hirtl, M; Ostaku, J; Gabrijelčič, S; Sokolowski, A; Malle, E; Graier, WF; Madreiter-Sokolowski, CT Targeting enhanced mitochondrial respiration chain activity as a potential therapeutic approach for endometriosis.
Biochim Biophys Acta Mol Basis Dis. 2025; 167885 Doi: 10.1016/j.bbadis.2025.167885
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2024

Full paper/article (Journal)

** Slanovc, J; Mikulčić, M; Jahn, N; Wizsy, NGT; Sattler, W; Malle, E; Hrzenjak, A Prostaglandin 15d-PGJ₂ inhibits proliferation of lung adenocarcinoma cells by inducing ROS production and activation of apoptosis via sirtuin-1.
Biochim Biophys Acta Mol Basis Dis. 2024; 1870(1):166924 Doi: 10.1016/j.bbadis.2023.166924
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** Tawfik, I; Schlick, K; Ostaku, J; Bresilla, D; Gabrijelčič, S; Gottschalk, B; Sokolowski, A; Malle, E; Kalinova, K; Hirtl, M; Madreiter-Sokolowski, CT Breast cancer cells utilize T3 to trigger proliferation through cellular Ca²⁺ modulation.
Cell Commun Signal. 2024; 22(1): 533 Doi: 10.1186/s12964-024-01917-y [OPEN ACCESS]
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Review

** Madreiter-Sokolowski, CT; Hiden, U; Krstic, J; Panzitt, K; Wagner, M; Enzinger, C; Khalil, M; Abdellatif, M; Malle, E; Madl, T; Osto, E; Schosserer, M; Binder, CJ; Olschewski, A Targeting organ-specific mitochondrial dysfunction to improve biological aging.
Pharmacol Ther. 2024; 262:108710 Doi: 10.1016/j.pharmthera.2024.108710
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2023

Full paper/article (Journal)

** Jørgensen, SM; Lorentzen, LG; Hammer, A; Hoefler, G; Malle, E; Chuang, CY; Davies, MJ The inflammatory oxidant peroxynitrous acid modulates the structure and function of the recombinant human V3 isoform of the extracellular matrix proteoglycan versican.
Redox Biol. 2023; 64: 102794 Doi: 10.1016/j.redox.2023.102794 [OPEN ACCESS]
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** Wang, YH; Hammer, A; Hoefler, G; Malle, E; Hawkins, CL; Chuang, CY; Davies, MJ Hypochlorous Acid and Chloramines Induce Specific Fragmentation and Cross-Linking of the G1-IGD-G2 Domains of Recombinant Human Aggrecan, and Inhibit ADAMTS1 Activity
ANTIOXIDANTS-BASEL. 2023; 12(2): 420 Doi: 10.3390/antiox12020420 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Abstract (Journal)

** Xu, SQ; Zhang, X; Yang-Jensen, K; Lorentzen, L; Chuang, C; Malle, E; Gamon, L; Hawkins, C; Davies, M Modulation of chlorination and nitration by myeloperoxidase in cardiovascular disease
FREE RADICAL BIO MED. 2023; 208: S84-S84. Doi: 10.1016/j.freeradbiomed.2023.10.189 [Poster]
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2022

Full paper/article (Journal)

** Koyani, CN; Scheruebel, S; Jin, G; Kolesnik, E; Zorn-Pauly, K; Mächler, H; Hoefler, G; von, Lewinski, D; Heinzel, FR; Pelzmann, B; Malle, E Hypochlorite-Modified LDL Induces Arrhythmia and Contractile Dysfunction in Cardiomyocytes.
Antioxidants (Basel). 2021; 11(1): Doi: 10.3390/antiox11010025 [OPEN ACCESS]
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** Reynolds, WF; Malle, E; Maki, RA Thiocyanate Reduces Motor Impairment in the hMPO-A53T PD Mouse Model While Reducing MPO-Oxidation of Alpha Synuclein in Enlarged LYVE1/AQP4 Positive Periventricular Glymphatic Vessels
ANTIOXIDANTS-BASEL. 2022; 11(12): 2342 Doi: 10.3390/antiox11122342 [OPEN ACCESS]
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** Xu, S; Chuang, CY; Malle, E; Gamon, LF; Hawkins, CL; Davies, MJ Influence of plasma halide, pseudohalide and nitrite ions on myeloperoxidase-mediated protein and extracellular matrix damage.
Free Radic Biol Med. 2022; 188:162-174 Doi: 10.1016/j.freeradbiomed.2022.06.222
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Review

** Arnhold, J; Malle, E Halogenation Activity of Mammalian Heme Peroxidases.
Antioxidants (Basel). 2022; 11(5): Doi: 10.3390/antiox11050890 [OPEN ACCESS]
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** Thomas, C; Wurzer, L; Malle, E; Ristow, M; Madreiter-Sokolowski, CT Modulation of Reactive Oxygen Species Homeostasis as a Pleiotropic Effect of Commonly Used Drugs.
Front Aging. 2022; 3: 905261 Doi: 10.3389/fragi.2022.905261 [OPEN ACCESS]
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2021

Full paper/article (Journal)

** Hall, L; Guo, C; Tandy, S; Broadhouse, K; Dona, AC; Malle, E; Bartels, ED; Christoffersen, C; Grieve, SM; Figtree, G; Hawkins, CL; Davies, MJ Oral pre-treatment with thiocyanate (SCN^-) protects against myocardial ischaemia-reperfusion injury in rats.
Sci Rep. 2021; 11(1):12712 Doi: 10.1038/s41598-021-92142-x [OPEN ACCESS]
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** Maiocchi, S; Ku, J; Hawtrey, T; De Silvestro, I; Malle, E; Rees, M; Thomas, SR; Morris, JC Polyamine-Conjugated Nitroxides Are Efficacious Inhibitors of Oxidative Reactions Catalyzed by Endothelial-Localized Myeloperoxidase
CHEM RES TOXICOL. 2021; 34(6): 1681-1692. Doi: 10.1021/acs.chemrestox.1c00094
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** Mikulčić, M; Tabrizi-Wizsy, NG; Bernhart, EM; Asslaber, M; Trummer, C; Windischhofer, W; Sattler, W; Malle, E; Hrzenjak, A 15d-PGJ₂ Promotes ROS-Dependent Activation of MAPK-Induced Early Apoptosis in Osteosarcoma Cell In Vitro and in an Ex Ovo CAM Assay.
Int J Mol Sci. 2021; 22(21): Doi: 10.3390/ijms222111760 [OPEN ACCESS]
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** Richter, G; Gui, T; Bourgeois, B; Koyani, CN; Ulz, P; Heitzer, E; von, Lewinski, D; Burgering, BMT; Malle, E; Madl, T β-catenin regulates FOXP2 transcriptional activity via multiple binding sites.
FEBS J. 2021; 288(10):3261-3284 Doi: 10.1111/febs.15656 [OPEN ACCESS]
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** Thai, T; Zhong, F; Dang, L; Chan, E; Ku, J; Malle, E; Geczy, CL; Keaney, JF; Thomas, SR Endothelial-transcytosed myeloperoxidase activates endothelial nitric oxide synthase via a phospholipase C-dependent calcium signaling pathway.
FREE RADICAL BIO MED. 2021; 166(2): 255-264. Doi: 10.1016/j.freeradbiomed.2020.12.448 [OPEN ACCESS]
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2020

Full paper/article (Journal)

** Goeritzer, M; Bernhart, E; Plastira, I; Reicher, H; Leopold, C; Eichmann, TO; Rechberger, G; Madreiter-Sokolowski, CT; Prasch, J; Eller, P; Graier, WF; Kratky, D; Malle, E; Sattler, W Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro.
Int J Mol Sci. 2020; 21(3): Doi: 10.3390/ijms21031143 [OPEN ACCESS]
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** Kälsch, AI; Scharnagl, H; Kleber, ME; Windpassinger, C; Sattler, W; Leipe, J; Krämer, BK; März, W; Malle, E Long- and short-term association of low-grade systemic inflammation with cardiovascular mortality in the LURIC study.
Clin Res Cardiol. 2020; 109(3):358-373 Doi: 10.1007/s00392-019-01516-9
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** Koyani, CN; Plastira, I; Sourij, H; Hallström, S; Schmidt, A; Rainer, PP; Bugger, H; Frank, S; Malle, E; von, Lewinski, D Empagliflozin protects heart from inflammation and energy depletion via AMPK activation.
Pharmacol Res. 2020; 158:104870 Doi: 10.1016/j.phrs.2020.104870
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** Leskelä, J; Pietiäinen, M; Safer, A; Lehto, M; Metso, J; Malle, E; Buggle, F; Becher, H; Sundvall, J; Grau, AJ; Pussinen, PJ; Palm, F Serum lipopolysaccharide neutralizing capacity in ischemic stroke.
PLoS One. 2020; 15(2): e0228806-e0228806. Doi: 10.1371/journal.pone.0228806 [OPEN ACCESS]
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** Plastira, I; Bernhart, E; Joshi, L; Koyani, CN; Strohmaier, H; Reicher, H; Malle, E; Sattler, W MAPK signaling determines lysophosphatidic acid (LPA)-induced inflammation in microglia.
J Neuroinflammation. 2020; 17(1): 127-127. Doi: 10.1186/s12974-020-01809-1 [OPEN ACCESS]
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** Prasch, J; Bernhart, E; Reicher, H; Kollroser, M; Rechberger, GN; Koyani, CN; Trummer, C; Rech, L; Rainer, PP; Hammer, A; Malle, E; Sattler, W Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro.
Int J Mol Sci. 2020; 21(23): Doi: 10.3390/ijms21239235 [OPEN ACCESS]
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** Smole, U; Gour, N; Phelan, J; Hofer, G; Köhler, C; Kratzer, B; Tauber, PA; Xiao, X; Yao, N; Dvorak, J; Caraballo, L; Puerta, L; Rosskopf, S; Chakir, J; Malle, E; Lane, AP; Pickl, WF; Lajoie, S; Wills-Karp, M Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity.
Nat Immunol. 2020; 21(7):756-765 Doi: 10.1038/s41590-020-0698-1 [OPEN ACCESS]
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2019

Full paper/article (Journal)

** Bhat, VK; Bernhart, E; Plastira, I; Fan, K; Ghaffari-Tabrizi-Wizsy, N; Wadsack, C; Rechberger, G; Eichmann, T; Asslaber, M; Spassova, I; Verhaegen, ME; Malle, E; Becker, JC; Sattler, W Pharmacological Inhibition of Serine Palmitoyl Transferase and Sphingosine Kinase-1/-2 Inhibits Merkel Cell Carcinoma Cell Proliferation.
J Invest Dermatol. 2019; 139(4):807-817 Doi: 10.1016/j.jid.2018.10.024 [OPEN ACCESS]
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** Fanaee-Danesh, E; Gali, CC; Tadic, J; Zandl-Lang, M; Carmen Kober, A; Agujetas, VR; de Dios, C; Tam-Amersdorfer, C; Stracke, A; Albrecher, NM; Manavalan, APC; Reiter, M; Sun, Y; Colell, A; Madeo, F; Malle, E; Panzenboeck, U Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(9): 2224-2245. Doi: 10.1016/j.bbadis.2019.04.019 [OPEN ACCESS]
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** Maki, RA; Holzer, M; Motamedchaboki, K; Malle, E; Masliah, E; Marsche, G; Reynolds, WF Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment.
Free Radic Biol Med. 2019; 141:115-140 Doi: 10.1016/j.freeradbiomed.2019.05.033 [OPEN ACCESS]
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** Nybo, T; Dieterich, S; Gamon, LF; Chuang, CY; Hammer, A; Hoefler, G; Malle, E; Rogowska-Wrzesinska, A; Davies, MJ Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase.
Redox Biol. 2019; 20:496-513 Doi: 10.1016/j.redox.2018.10.022 [OPEN ACCESS]
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** Vanichkitrungruang, S; Chuang, CY; Hawkins, CL; Hammer, A; Hoefler, G; Malle, E; Davies, MJ Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function.
Free Radic Biol Med. 2019; 136(Suppl 1): 118-134. Doi: 10.1016/j.freeradbiomed.2019.04.003
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Abstract (Journal)

** Kalsch, AI; Kleber, M; Sattler, W; Kramer, BK; Marz, W; Malle, E; Leipe, J; Scharnagl, H LONG- AND SHORT-TERM ASSOCIATION OF LOW-GRADE SYSTEMIC INFLAMMATION WITH CARDIOVASCULAR MORTALITY
J HYPERTENS. 2019; 37: E295-E295.-29th European Meeting of Hypertension and Cardiovascular Protection of the European-Society-of-Hypertension (ESH); JUN 21-24, 2019; Milan, ITALY. Doi: 10.1097/01.hjh.0000573732.10100.c2 [Oral Communication]
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** Kolesnik, E; Koyani, C; Trummer, C; Djalinac, N; Lechleitner, M; Scherubel, S; Sourij, H; Bisping, E; Schmidt, A; Machler, H; Frank, S; Sattler, W; Malle, E; Pelzmann, B; von Lewinski, D Protective effects of empagliflozin against LPS-induced cardiovascular dysfunction
WIEN KLIN WOCHENSCHR. 2019; 131: 337-337. [Oral Communication]
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** Leipe, J; Kaelsch, AI; Kleber, M; Scharnagl, H; Sattler, W; Marz, W; Malle, E; Kraemer, B LONG- AND SHORT-TERM ASSOCIATION OF LOW-GRADE SYSTEMIC INFLAMMATION WITH CARDIOVASCULAR MORTALITY
ANN RHEUM DIS. 2019; 78: 1028-1028.-Annual European Congress of Rheumatology (EULAR); JUN 12-15, 2019; Madrid, SPAIN. Doi: 10.1136/annrheumdis-2019-eular.7919 [Oral Communication] [OPEN ACCESS]
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2018

Full paper/article (Journal)

** Bernhart, E; Kogelnik, N; Prasch, J; Gottschalk, B; Goeritzer, M; Depaoli, MR; Reicher, H; Nusshold, C; Plastira, I; Hammer, A; Fauler, G; Malli, R; Graier, WF; Malle, E; Sattler, W 2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells.
Redox Biol. 2018; 15:441-451 Doi: 10.1016/j.redox.2018.01.003 [OPEN ACCESS]
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** Degendorfer, G; Chuang, CY; Mariotti, M; Hammer, A; Hoefler, G; Hägglund, P; Malle, E; Wise, SG; Davies, MJ Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function.
Free Radic Biol Med. 2018; 115:219-231 Doi: 10.1016/j.freeradbiomed.2017.11.019
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** Koyani, CN; Trummer, C; Shrestha, N; Scheruebel, S; Bourgeois, B; Plastira, I; Kickmaier, S; Sourij, H; Rainer, PP; Madl, T; Sattler, W; Pelzmann, B; Malle, E; von Lewinski, D Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes.
Front Physiol. 2018; 9:1622-1622 Doi: 10.3389/fphys.2018.01622 [OPEN ACCESS]
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Editorial

** Pussinen, PJ; Malle, E; Sattler, W Importance of maintaining good oral health in cardiometabolic disorders.
Int J Cardiol. 2018; 271(10):291-292 Doi: 10.1016/j.ijcard.2018.07.014 [OPEN ACCESS]
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Abstract (Journal)

** Degendorfer, G; Lorentzen, L; Chuang, C; Mariotti, M; Hammer, A; Hoefler, G; Hagglund, P; Malle, E; Davies, M; Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function.
FREE RADICAL BIOL MED. 2018; 128: S31-S31.-25th Annual Meeting of the Society-for-Redox-Biology-and-Medicine (SfRBM); NOV 14-17, 2018; Chicago, IL. Doi: 10.1016/j.freeradbiomed.2018.10.032 [Oral Communication]
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** Degendorfer, G; Lorentzen, LG; Chuang, CY; Mariotti, M; Hammer, A; Hoefler, G; Hagglund, P; Malle, E; Wise, S; Davies, MJ Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function
FREE RADICAL BIO MED. 2018; 120: S102-S103.-19th Biennial Meeting of the Society-for-Free-Radical-Research-International (SFRRI); 2018; Lisbon, PORTUGAL. Doi: 10.1016/j.freeradbiomed.2018.04.339 [Oral Communication]
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** Koyani, C; Trummer, C; Plastira, I; Lechleitner, M; Scherubel, S; Sourij, H; Sasa, F; Sattler, W; Malle, E; von Lewinski, D Withaferin A attenuates inflammatory response and cardiovascular dysfunction induced by LPS
WIEN KLIN WOCHENSCHR. 2018; 130: 42-42. [Poster]
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** Nybo, T; Deiterich, S; Gamon, L; Chuang, C; Hammer, A; Hoefler, G; Malle, E; Rogowska-Wrzesinska, A; Davies, M; Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase.
FREE RADICAL BIOL MED. 2018; 128: S49-S50.-25th Annual Meeting of the Society-for-Redox-Biology-and-Medicine (SfRBM); NOV 14-17, 2018; Chicago, IL. Doi: 10.1016/j.freeradbiomed.2018.10.084 [Oral Communication]
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2017

Full paper/article (Journal)

** Koyani, CN; Kolesnik, E; Wölkart, G; Shrestha, N; Scheruebel, S; Trummer, C; Zorn-Pauly, K; Hammer, A; Lang, P; Reicher, H; Maechler, H; Groschner, K; Mayer, B; Rainer, PP; Sourij, H; Sattler, W; Malle, E; Pelzmann, B; von, Lewinski, D Dipeptidyl peptidase-4 independent cardiac dysfunction links saxagliptin to heart failure.
Biochem Pharmacol. 2017; 145:64-80 Doi: 10.1016/j.bcp.2017.08.021 [OPEN ACCESS]
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** Plastira, I; Bernhart, E; Goeritzer, M; DeVaney, T; Reicher, H; Hammer, A; Lohberger, B; Wintersperger, A; Zucol, B; Graier, WF; Kratky, D; Malle, E; Sattler, W Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype.
J Neuroinflammation. 2017; 14(1):253-253 Doi: 10.1186/s12974-017-1024-1 [OPEN ACCESS]
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** Wölkart, G; Schrammel, A; Koyani, CN; Scherübel, S; Zorn-Pauly, K; Malle, E; Pelzmann, B; Andrä, M; Ortner, A; Mayer, B Cardioprotective effects of 5-hydroxymethylfurfural mediated by inhibition of L-type Ca(2+) currents.
Br J Pharmacol. 2017; 174(20):3640-3653 Doi: 10.1111/bph.13967 [OPEN ACCESS]
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Abstract (Journal)

** Chuang, CY; Degendorfer, G; Lorentzen, L; Hammer, A; Whitelock, JM; Malle, E; Davies, MJ Inflammatory oxidants modify components of the extracellular matrix of human atherosclerotic lesions
INT J EXP PATHOL. 2017; 98(3):A5-A6.-Spring Meeting of the British-Society-for-Matrix-Biology (BSMB); APR 03-04, 2017; Univ Oxford, Oxford, ENGLAND. [Oral Communication]
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** Lorentzen, LG; Degendorfer, G; Chuang, CY; Hammer, A; Malle, E; Davies, MJ The inflammatory oxidant peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin
INT J EXP PATHOL. 2017; 98(3):A9-A9.-Spring Meeting of the British-Society-for-Matrix-Biology (BSMB); APR 03-04, 2017; Univ Oxford, Oxford, ENGLAND. [Oral Communication]
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** Vanichkitrungruang, S; Chuang, CY; Degendorfer, G; Hammer, A; Malle, E; Davies, MJ Mechanism of damage to arterial extracellular derived fibronectin by myeloperoxidase-derived oxidants during chronic inflammation
INT J EXP PATHOL. 2017; 98(3):A6-A6.-Spring Meeting of the British-Society-for-Matrix-Biology (BSMB); APR 03-04, 2017; Univ Oxford, Oxford, ENGLAND. [Oral Communication]
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2016

Full paper/article (Journal)

** Degendorfer, G; Chuang, CY; Kawasaki, H; Hammer, A; Malle, E; Yamakura, F; Davies, MJ Peroxynitrite-mediated oxidation of plasma fibronectin.
Free Radic Biol Med. 2016; 97(3):602-615 Doi: 10.1016/j.freeradbiomed.2016.06.013
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** Koyani, CN; Kitz, K; Rossmann, C; Bernhart, E; Huber, E; Trummer, C; Windischhofer, W; Sattler, W; Malle, E Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death.
Biochem Pharmacol. 2016; 104:29-41 Doi: 10.1016/j.bcp.2016.01.011 [OPEN ACCESS]
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** Nusshold, C; Üllen, A; Kogelnik, N; Bernhart, E; Reicher, H; Plastira, I; Glasnov, T; Zangger, K; Rechberger, G; Kollroser, M; Fauler, G; Wolinski, H; Weksler, BB; Romero, IA; Kohlwein, SD; Couraud, PO; Malle, E; Sattler, W Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal.
Free Radic Biol Med. 2016; 90: 59-74. Doi: 10.1016/j.freeradbiomed.2015.11.010 [OPEN ACCESS]
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** Plastira, I; Bernhart, E; Goeritzer, M; Reicher, H; Kumble, VB; Kogelnik, N; Wintersperger, A; Hammer, A; Schlager, S; Jandl, K; Heinemann, A; Kratky, D; Malle, E; Sattler, W 1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype.
J Neuroinflammation. 2016; 13(1): 205-205. Doi: 10.1186/s12974-016-0701-9 [OPEN ACCESS]
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** Rezania, S; Kammerer, S; Li, C; Steinecker-Frohnwieser, B; Gorischek, A; DeVaney, TT; Verheyen, S; Passegger, CA; Tabrizi-Wizsy, NG; Hackl, H; Platzer, D; Zarnani, AH; Malle, E; Jahn, SW; Bauernhofer, T; Schreibmayer, W Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner.
BMC Cancer. 2016; 16(1):628-628 Doi: 10.1186/s12885-016-2664-8 [OPEN ACCESS]
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Review

** Alfakry, H; Malle, E; Koyani, CN; Pussinen, PJ; Sorsa, T Neutrophil proteolytic activation cascades: a possible mechanistic link between chronic periodontitis and coronary heart disease.
Innate Immun. 2016; 22(1):85-99 Doi: 10.1177/1753425915617521 [OPEN ACCESS]
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Abstract (Journal)

** Chuang, CY; Degendorfer, G; Hammer, A; Whitelock, JM; Malle, E; Davies, MJ The potent inflammatory oxidant, peroxynitrite, modifies the extracellular matrix of human atherosclerotic lesions
FREE RADICAL BIO MED. 2016; 96: S45-S45.-Conference of the Society-for-Free-Radical-Research-Europe (SFRR-E); JUN 08-11, 2016; Budapest, HUNGARY. Doi: 10.1016/j.freeradbiomed.2016.04.093 [Oral Communication]
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** Kolesnik, E; Koyani, C; Wallner, M; Khafaga, M; Scherubel, S; Djalinac, N; Sourij, H; Machler, H; Malle, E; Pelzmann, B; von Lewinski, D DPP-4 inhibitors impair contraction and relaxation in human atrial trabeculae and electrophysiological function in guinea pig ventricular cardiomyocytes
WIEN KLIN WOCHENSCHR. Wiener Klinische Wochenschrift, supplement 6/16. 2016; 128: S410-S412.-44. Jahrestagung der Österreichischen Diabetes Gesellschaft; NOV 17-19, 2016; Salzburg. [Oral Communication]
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** Woolbright, B; Dunn, W; Olson, JC; Malle, E; Jaeschke, H Cell Death Biomarkers in Patients with Alcoholic Liver Disease
HEPATOLOGY. 2016; 63(1 SUPP):607A-607A.-67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 11-15, 2016; Boston, MA.
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2015

Full paper/article (Journal)

** Bernhart, E; Damm, S; Wintersperger, A; Nusshold, C; Brunner, AM; Plastira, I; Rechberger, G; Reicher, H; Wadsack, C; Zimmer, A; Malle, E; Sattler, W Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells.
Biochem Pharmacol. 2015; 96(2): 119-130. Doi: 10.1016/j.bcp.2015.05.007 [OPEN ACCESS]
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** Degendorfer, G; Chuang, CY; Hammer, A; Malle, E; Davies, MJ Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin.
Free Radic Biol Med. 2015; 89(48):721-733 Doi: 10.1016/j.freeradbiomed.2015.09.018
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** Jain, P; Hassan, AM; Koyani, CN; Mayerhofer, R; Reichmann, F; Farzi, A; Schuligoi, R; Malle, E; Holzer, P Behavioral and molecular processing of visceral pain in the brain of mice: impact of colitis and psychological stress.
Front Behav Neurosci. 2015; 9(5):177-177 Doi: 10.3389/fnbeh.2015.00177 [OPEN ACCESS]
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** Koyani, CN; Flemmig, J; Malle, E; Arnhold, J Myeloperoxidase scavenges peroxynitrite: A novel anti-inflammatory action of the heme enzyme.
Arch Biochem Biophys. 2015; 571(7):1-9 Doi: 10.1016/j.abb.2015.02.028 [OPEN ACCESS]
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** Li, C; Rezania, S; Kammerer, S; Sokolowski, A; Devaney, T; Gorischek, A; Jahn, S; Hackl, H; Groschner, K; Windpassinger, C; Malle, E; Bauernhofer, T; Schreibmayer, W Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line.
Sci Rep. 2015; 5(2):8364-8364 Doi: 10.1038/srep08364 [OPEN ACCESS]
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** Üllen, A; Nusshold, C; Glasnov, T; Saf, R; Cantillo, D; Eibinger, G; Reicher, H; Fauler, G; Bernhart, E; Hallstrom, S; Kogelnik, N; Zangger, K; Oliver Kappe, C; Malle, E; Sattler, W Covalent adduct formation between the plasmalogen-derived modification product 2-chlorohexadecanal and phloretin.
Biochem Pharmacol. 2015; 93(4):470-481 Doi: 10.1016/j.bcp.2014.12.017 [OPEN ACCESS]
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Correction

** Koyani, CN; Windischhofer, W; Rossmann, C; Heinzel, FR; Sattler, W; Malle, E Is recurrent pericarditis a risk for constrictive evolution? Reply (vol 177, pg 140, 2014)
INT J CARDIOL. 2015; 189: 108-108. Doi: 10.1016/j.ijcard.2014.12.040
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Abstract (Journal)

** Degendorfer, G; Chuang, CY; Hammer, A; Malle, E; Davies, MJ Laminin, a key component of tissue extracellular matrix, is a major target for peroxynitrous acid
FREE RADICAL BIO MED. 2015; 86: S12-S13.-SFRR-E/SNFS Conference; SEP 02-04, 2015; Stuttgart, GERMANY. Doi: 10.1016/j.freeradbiomed.2015.07.055 [Oral Communication]
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** Jain, P; Hassan, AM; Koyani, CN; Mayerhofer, R; Reichmann, F; Farzi, A; Schuligoi, R; Malle, E; Holzer, P Behavioral and molecular processing of visceral pain in the brain of mice: Impact of colitis and psychological stress
NEUROGASTROENT MOTIL. 2015; 27: 24-24.-NeuroGastro 2015; June 6-4, 2015; Istanbul, Turkey. [Oral Communication]
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2014

Full paper/article (Journal)

** Bernkopf, M; Webersinke, G; Tongsook, C; Koyani, CN; Rafiq, MA; Ayaz, M; Müller, D; Enzinger, C; Aslam, M; Naeem, F; Schmidt, K; Gruber, K; Speicher, MR; Malle, E; Macheroux, P; Ayub, M; Vincent, JB; Windpassinger, C; Duba, HC Disruption of the methyltransferase-like 23 gene METTL23 causes mild autosomal recessive intellectual disability.
Hum Mol Genet. 2014; 23(15):4015-4023 Doi: 10.1093/hmg/ddu115 [OPEN ACCESS]
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** Chuang, CY; Degendorfer, G; Hammer, A; Whitelock, JM; Malle, E; Davies, MJ Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells.
Biochem J. 2014; 459(2):313-322 Doi: 10.1042/BJ20131471 [OPEN ACCESS]
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** Delporte, C; Boudjeltia, KZ; Noyon, C; Furtmüller, PG; Nuyens, V; Slomianny, MC; Madhoun, P; Desmet, JM; Raynal, P; Dufour, D; Koyani, CN; Reyé, F; Rousseau, A; Vanhaeverbeek, M; Ducobu, J; Michalski, JC; Nève, J; Vanhamme, L; Obinger, C; Malle, E; Van Antwerpen, P Impact of myeloperoxidase-LDL interactions on enzyme activity and subsequent posttranslational oxidative modifications of apoB-100.
J Lipid Res. 2014; 55(4):747-757 Doi: 10.1194/jlr.M047449 [OPEN ACCESS]
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** Koyani, CN; Windischhofer, W; Rossmann, C; Jin, G; Kickmaier, S; Heinzel, FR; Groschner, K; Alavian-Ghavanini, A; Sattler, W; Malle, E 15-deoxy-Δ¹²,¹⁴-PGJ₂ promotes inflammation and apoptosis in cardiomyocytes via the DP2/MAPK/TNFα axis.
Int J Cardiol. 2014; 173(3):472-480 Doi: 10.1016/j.ijcard.2014.03.086 [OPEN ACCESS]
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** Rossmann, C; Hammer, A; Koyani, CN; Kovacevic, A; Siwetz, M; Desoye, G; Poehlmann, TG; Markert, UR; Huppertz, B; Sattler, W; Malle, E Expression of serum amyloid A4 in human trophoblast-like choriocarcinoma cell lines and human first trimester/term trophoblast cells.
Placenta. 2014; 35(8):661-664 Doi: 10.1016/j.placenta.2014.05.012 [OPEN ACCESS]
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** Rossmann, C; Windpassinger, C; Brunner, D; Kovacevic, A; Schweighofer, N; Malli, R; Schuligoi, R; Prokesch, A; Kluve-Beckerman, B; Graier, WF; Kratky, D; Sattler, W; Malle, E Characterization of rat serum amyloid A4 (SAA4): a novel member of the SAA superfamily.
Biochem Biophys Res Commun. 2014; 450(4):1643-1649 Doi: 10.1016/j.bbrc.2014.07.054 [OPEN ACCESS]
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** Scharnagl, H; Kleber, ME; Genser, B; Kickmaier, S; Renner, W; Weihrauch, G; Grammer, T; Rossmann, C; Winkelmann, BR; Boehm, BO; Sattler, W; März, W; Malle, E Association of myeloperoxidase with total and cardiovascular mortality in individuals undergoing coronary angiography--the LURIC study.
Int J Cardiol. 2014; 174(1):96-105 Doi: 10.1016/j.ijcard.2014.03.168 [OPEN ACCESS]
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** Scheruebel, S; Koyani, CN; Hallström, S; Lang, P; Platzer, D; Mächler, H; Lohner, K; Malle, E; Zorn-Pauly, K; Pelzmann, B I(f) blocking potency of ivabradine is preserved under elevated endotoxin levels in human atrial myocytes.
J Mol Cell Cardiol. 2014; 72:64-73 Doi: 10.1016/j.yjmcc.2014.02.010 [OPEN ACCESS]
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Correspondence

** Koyani, CN; Windischhofer, W; Rossmann, C; Heinzel, FR; Sattler, W; Malle, E Response to letter by Tsikas et al.
INT J CARDIOL. 2014; 177(1): 140-141. Doi: 10.1016/j.ijcard.2014.09.111
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2013

Full paper/article (Journal)

** Carmona-Gutierrez, D; Alavian-Ghavanini, A; Habernig, L; Bauer, MA; Hammer, A; Rossmann, C; Zimmermann, AS; Ruckenstuhl, C; Büttner, S; Eisenberg, T; Sattler, W; Malle, E; Madeo, F The cell death protease Kex1p is essential for hypochlorite-induced apoptosis in yeast.
Cell Cycle. 2013; 12(11):1704-1712 Doi: 10.4161/cc.24801 [OPEN ACCESS]
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** Costet, P; Ehrenborg, E; Fisher, R; Fielding, B; Groen, A; Kardassis, D; Malle, E; Mulder, M; Niemeier, A; Norata, GD; Hansen, AT; Eckardstein, AV European Lipoprotein Club: Report of the 35th ELC Annual Conference (Tutzing, 10th-13th September 2012).
Atherosclerosis. 2013; 226(2):510-516 Doi: 10.1016/j.atherosclerosis.2012.11.030
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** Eibinger, G; Fauler, G; Bernhart, E; Frank, S; Hammer, A; Wintersperger, A; Eder, H; Heinemann, A; Mischel, PS; Malle, E; Sattler, W On the role of 25-hydroxycholesterol synthesis by glioblastoma cell lines. Implications for chemotactic monocyte recruitment.
Exp Cell Res. 2013; 319(12):1828-1838 Doi: 10.1016/j.yexcr.2013.03.025 [OPEN ACCESS]
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** Kiss, E; Kränzlin, B; Wagenblaβ, K; Bonrouhi, M; Thiery, J; Gröne, E; Nordström, V; Teupser, D; Gretz, N; Malle, E; Gröne, HJ Lipid droplet accumulation is associated with an increase in hyperglycemia-induced renal damage: prevention by liver X receptors.
Am J Pathol. 2013; 182(3):727-741 Doi: 10.1016/j.ajpath.2012.11.033 [OPEN ACCESS]
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** Lu, J; Roth, RA; Malle, E; Ganey, PE Roles of the hemostatic system and neutrophils in liver injury from co-exposure to amiodarone and lipopolysaccharide.
Toxicol Sci. 2013; 136(1):51-62 Doi: 10.1093/toxsci/kft170 [OPEN ACCESS]
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** Nusshold, C; Uellen, A; Bernhart, E; Hammer, A; Damm, S; Wintersperger, A; Reicher, H; Hermetter, A; Malle, E; Sattler, W Endocytosis and intracellular processing of BODIPY-sphingomyelin by murine CATH.a neurons.
Biochim Biophys Acta. 2013; 1831(12):1665-1678 Doi: 10.1016/j.bbalip.2013.08.007 [OPEN ACCESS]
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** Üllen, A; Singewald, E; Konya, V; Fauler, G; Reicher, H; Nusshold, C; Hammer, A; Kratky, D; Heinemann, A; Holzer, P; Malle, E; Sattler, W Myeloperoxidase-derived oxidants induce blood-brain barrier dysfunction in vitro and in vivo.
PLoS One. 2013; 8(5):e64034-e64034 Doi: 10.1371/journal.pone.0064034 [OPEN ACCESS]
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** Waltl-Patankar, S; Patankar, J; Fauler, G; Nusshold, C; Ullen, A; Eibinger, G; Wintersperger, A; Kratky, D; Malle, E; Sattler, W 25-Hydroxycholesterol regulates cholesterol homeostasis in the murine CATH.a neuronal cell line.
Neurosci Lett. 2013; 539(4):16-21 Doi: 10.1016/j.neulet.2013.01.014 [OPEN ACCESS]
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2012

Full paper/article (Journal)

** Bernini, F; Costet, P; Ehrenborg, E; Fisher, R; Fielding, B; Freeman, D; Groen, A; Malle, E; Mulder, M; Niemeier, A; Hansen, AT; von Eckardstein, A European Lipoprotein Club: Report of the 34th ELC annual conference, Tutzing, 5-8 September 2011.
Atherosclerosis. 2012; 221(1):287-293 Doi: 10.1016/j.atherosclerosis.2011.12.002
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** Porubsky, S; Speak, AO; Salio, M; Jennemann, R; Bonrouhi, M; Zafarulla, R; Singh, Y; Dyson, J; Luckow, B; Lehuen, A; Malle, E; Müthing, J; Platt, FM; Cerundolo, V; Gröne, HJ Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells.
J Immunol. 2012; 189(6):3007-3017 Doi: 10.4049/jimmunol.1201483 [OPEN ACCESS]
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** Rees, MD; Dang, L; Thai, T; Owen, DM; Malle, E; Thomas, SR Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells.
Free Radic Biol Med. 2012; 53(12):2344-2356 Doi: 10.1016/j.freeradbiomed.2012.10.002 [OPEN ACCESS]
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** Ullen, A; Fauler, G; Bernhart, E; Nusshold, C; Reicher, H; Leis, HJ; Malle, E; Sattler, W Phloretin ameliorates 2-chlorohexadecanal-mediated brain microvascular endothelial cell dysfunction in vitro.
Free Radic Biol Med. 2012; 53(9):1770-1781 Doi: 10.1016/j.freeradbiomed.2012.08.575 [OPEN ACCESS]
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** Windischhofer, W; Huber, E; Rossmann, C; Semlitsch, M; Kitz, K; Rauh, A; Devaney, T; Leis, HJ; Malle, E LPA-induced suppression of periostin in human osteosarcoma cells is mediated by the LPA(1)/Egr-1 axis.
Biochimie. 2012; 94(9):1997-2005 Doi: 10.1016/j.biochi.2012.05.023 [OPEN ACCESS]
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Abstract (Journal)

** Chuang, CY; Degendorfer, G; Hammer, A; Malle, E; Whitelock, JM; Davies, MJ; Peroxynitrite Modulates Endothelial Cell-Derived Extracellular Matrix in Human Atherosclerotic Lesions.
FREE RADICAL BIOL MED. 2012; 53: S134-S134.-19th Annual Meeting of the Society-for-Free-Radical-Biology-and-Medicine (SFRBM); NOV 14-18, 2012; San Diego, CA. Doi: 10.1016/j.freeradbiomed.2012.10.364 [Oral Communication]
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2011

Full paper/article (Journal)

** Kitz, K; Windischhofer, W; Leis, HJ; Huber, E; Kollroser, M; Malle, E 15-Deoxy-Δ12,14-prostaglandin J2 induces Cox-2 expression in human osteosarcoma cells through MAPK and EGFR activation involving reactive oxygen species.
Free Radic Biol Med. 2011; 50(7):854-865 Doi: 10.1016/j.freeradbiomed.2010.12.039
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** Poparic, I; Schreibmayer, W; Schoser, B; Desoye, G; Gorischek, A; Miedl, H; Hochmeister, S; Binder, J; Quasthoff, S; Wagner, K; Windpassinger, C; Malle, E Four and a half LIM protein 1C (FHL1C): a binding partner for voltage-gated potassium channel K(v1.5).
PLOS ONE. 2011; 6(10): e26524-e26524. Doi: 10.1371/journal.pone.0026524 [OPEN ACCESS]
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** Resch, U; Semlitsch, M; Hammer, A; Susani-Etzerodt, H; Walczak, H; Sattler, W; Malle, E Hypochlorite-modified low-density lipoprotein induces the apoptotic machinery in Jurkat T-cell lines.
Biochem Biophys Res Commun. 2011; 410(4): 895-900. Doi: 10.1016/j.bbrc.2011.06.089 [OPEN ACCESS]
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** Rossmann, C; Rauh, A; Hammer, A; Windischhofer, W; Zirkl, S; Sattler, W; Malle, E Hypochlorite-modified high-density lipoprotein promotes induction of HO-1 in endothelial cells via activation of p42/44 MAPK and zinc finger transcription factor Egr-1.
Arch Biochem Biophys. 2011; 509(1):16-25 Doi: 10.1016/j.abb.2011.02.016 [OPEN ACCESS]
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** Semlitsch, M; Shackelford, RE; Zirkl, S; Sattler, W; Malle, E ATM protects against oxidative stress induced by oxidized low-density lipoprotein.
DNA Repair (Amst). 2011; 10(8):848-860 Doi: 10.1016/j.dnarep.2011.05.004 [OPEN ACCESS]
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** Zou, W; Roth, RA; Younis, HS; Malle, E; Ganey, PE Neutrophil-cytokine interactions in a rat model of sulindac-induced idiosyncratic liver injury.
TOXICOLOGY. 2011; 290(2-3): 278-285. Doi: 10.1016/j.tox.2011.10.005 [OPEN ACCESS]
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Editorial

** Bernini, F; Fisher, R; Freeman, D; Groen, A; Kalopissis, A; Malle, E; Mulder, M; Niemeier, A; Parini, P; Hansen, AT; von Eckardstein, A Report of the 33rd annual conference of the European Lipoprotein Club, Tutzing, 6-9 September 2010.
Atherosclerosis. 2011; 215(1): 249-255. Doi: 10.1016/j.atherosclerosis.2010.12.002
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Correction

** Ullen, A; Fauler, G; Kofeler, H; Waltl, S; Nusshold, C; Bernhart, E; Reicher, H; Leis, HJ; Wintersperger, A; Malle, E; Sattler, W Mouse brain plasmalogens are targets for hypochlorous acid-mediated modification in vitro and in vivo (vol 49, pg 1655, 2010)
FREE RADICAL BIOL MED. 2011; 50(7): 903-903. Doi: 10.1016/j.freeradbiomed.2011.01.008
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2010

Full paper/article (Journal)

** Bernhart, E; Kollroser, M; Rechberger, G; Reicher, H; Heinemann, A; Schratl, P; Hallström, S; Wintersperger, A; Nusshold, C; DeVaney, T; Zorn-Pauly, K; Malli, R; Graier, W; Malle, E; Sattler, W Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture.
Proteomics. 2010; 10(1):141-158 Doi: 10.1002/pmic.200900195 [OPEN ACCESS]
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** Kennett, EC; Rees, MD; Malle, E; Hammer, A; Whitelock, JM; Davies, MJ Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains.
FREE RADICAL BIOL MED. 2010; 49(2): 282-293. Doi: 10.1016/j.freeradbiomed.2010.04.018 [OPEN ACCESS]
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** Nusshold, C; Kollroser, M; Köfeler, H; Rechberger, G; Reicher, H; Ullen, A; Bernhart, E; Waltl, S; Kratzer, I; Hermetter, A; Hackl, H; Trajanoski, Z; Hrzenjak, A; Malle, E; Sattler, W Hypochlorite modification of sphingomyelin generates chlorinated lipid species that induce apoptosis and proteome alterations in dopaminergic PC12 neurons in vitro.
Free Radic Biol Med. 2010; 48(12): 1588-1600. Doi: 10.1016/j.freeradbiomed.2010.02.037 [OPEN ACCESS]
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** Rees, MD; Whitelock, JM; Malle, E; Chuang, CY; Iozzo, RV; Nilasaroya, A; Davies, MJ Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan.
Matrix Biol. 2010; 29(1): 63-73. Doi: 10.1016/j.matbio.2009.09.005 [OPEN ACCESS]
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** Ullen, A; Fauler, G; Köfeler, H; Waltl, S; Nusshold, C; Bernhart, E; Reicher, H; Leis, HJ; Wintersperger, A; Malle, E; Sattler, W Mouse brain plasmalogens are targets for hypochlorous acid-mediated modification in vitro and in vivo.
Free Radic Biol Med. 2010; 49(11):1655-1665 Doi: 10.1016/j.freeradbiomed.2010.08.025 [OPEN ACCESS]
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Abstract (Journal)

** Kennett, E; Chuang, CY; Degendorfer, G; Rees, MD; Hammer, A; Malle, E; Whitelock, JM; Davies, MJ Extracellular Matrix Proteoglycans are a Major Target for Peroxynitrite in the Artery Wall
FREE RADICAL BIOL MED. 2010; 49: S113-S113. Doi: 10.1016/j.freeradbiomed.2010.10.302 [Poster]
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2009

Full paper/article (Journal)

** Chantepie, S; Malle, E; Sattler, W; Chapman, MJ; Kontush, A Distinct HDL subclasses present similar intrinsic susceptibility to oxidation by HOCl.
Arch Biochem Biophys. 2009; 487(1): 28-35. Doi: 10.1016/j.abb.2009.05.005 [OPEN ACCESS]
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** Kratzer, I; Bernhart, E; Wintersperger, A; Hammer, A; Waltl, S; Malle, E; Sperk, G; Wietzorrek, G; Dieplinger, H; Sattler, W Afamin is synthesized by cerebrovascular endothelial cells and mediates alpha-tocopherol transport across an in vitro model of the blood-brain barrier.
J Neurochem. 2009; 108(3): 707-718. Doi: 10.1111/j.1471-4159.2008.05796.x [OPEN ACCESS]
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** Malle, E; Sodin-Semrl, S; Kovacevic, A Serum amyloid A: an acute-phase protein involved in tumour pathogenesis.
Cell Mol Life Sci. 2009; 66(1): 9-26. Doi: 10.1007/s00018-008-8321-x [OPEN ACCESS]
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** Rees, MD; Bottle, SE; Fairfull-Smith, KE; Malle, E; Whitelock, JM; Davies, MJ Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides.
Biochem J. 2009; 421(1): 79-86. Doi: 10.1042/BJ20090309 [OPEN ACCESS]
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** Rensen, SS; Slaats, Y; Nijhuis, J; Jans, A; Bieghs, V; Driessen, A; Malle, E; Greve, JW; Buurman, WA Increased hepatic myeloperoxidase activity in obese subjects with nonalcoholic steatohepatitis.
Am J Pathol. 2009; 175(4): 1473-1482. Doi: 10.2353/ajpath.2009.080999 [OPEN ACCESS]
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Abstract (Journal)

** Kitz, K; Malle, E; Leis, HJ; Windischhofer, W 15-Deoxy-Delta(12,14)-prostaglandin J(2) induces Cox-2 expression and ROS-dependent apoptosis in human osteosarcoma cells
BONE. 2009; 45: S103-S104. Doi: 10.1016/j.bone.2009.04.172 [Poster]
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** Kitz, K; Malle, E; Leis, HJ; Windischhofer, W Peroxisome proliferator-activated receptor gamma agonists induce cyclooxygenase 2 expression and apoptosis in human osteosarcoma cells
BONE. 2009; 44(2):S285-S285.-European Symposium of Calcified Tissues; MAY 23-27, 2009; Vienna, AUSTRIA. Doi: 10.1016/j.bone.2009.03.511 [Poster]
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2008

Full paper/article (Journal)

** Deng, X; Lu, J; Lehman-McKeeman, LD; Malle, E; Crandall, D; Ganey, PE; Roth, RA p38 mitogen-activated protein kinase-dependent tumor necrosis factor-alpha-converting enzyme is important for liver injury in hepatotoxic interaction between lipopolysaccharide and ranitidine.
J Pharmacol Exp Ther. 2008; 326(1): 144-152. Doi: 10.1124/jpet.108.137497 [OPEN ACCESS]
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** Kovacevic, A; Hammer, A; Stadelmeyer, E; Windischhofer, W; Sundl, M; Ray, A; Schweighofer, N; Friedl, G; Windhager, R; Sattler, W; Malle, E Expression of serum amyloid A transcripts in human bone tissues, differentiated osteoblast-like stem cells and human osteosarcoma cell lines.
J Cell Biochem. 2008; 103(3): 994-1004. Doi: 10.1002/jcb.21472 [OPEN ACCESS]
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** Marsche, G; Furtmüller, PG; Obinger, C; Sattler, W; Malle, E Hypochlorite-modified high-density lipoprotein acts as a sink for myeloperoxidase in vitro.
Cardiovasc Res. 2008; 79(1): 187-194. Doi: 10.1093/cvr/cvn051 [OPEN ACCESS]
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** Rauh, A; Windischhofer, W; Kovacevic, A; DeVaney, T; Huber, E; Semlitsch, M; Leis, HJ; Sattler, W; Malle, E Endothelin (ET)-1 and ET-3 promote expression of c-fos and c-jun in human choriocarcinoma via ET(B) receptor-mediated G(i)- and G(q)-pathways and MAP kinase activation.
Br J Pharmacol. 2008; 154(1):13-24 Doi: 10.1038/bjp.2008.92 [OPEN ACCESS]
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2007

Full paper/article (Journal)

** Deng, X; Luyendyk, JP; Zou, W; Lu, J; Malle, E; Ganey, PE; Roth, RA Neutrophil interaction with the hemostatic system contributes to liver injury in rats cotreated with lipopolysaccharide and ranitidine.
J Pharmacol Exp Ther. 2007; 322(2): 852-861. Doi: 10.1124/jpet.107.122069 [OPEN ACCESS]
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** Hasegawa, T; Ito, Y; Wijeweera, J; Liu, J; Malle, E; Farhood, A; McCuskey, RS; Jaeschke, H Reduced inflammatory response and increased microcirculatory disturbances during hepatic ischemia-reperfusion injury in steatotic livers of ob/ob mice.
Am J Physiol Gastrointest Liver Physiol. 2007; 292(5): G1385-G1395. Doi: 10.1152/ajpgi.00246.2006 [OPEN ACCESS]
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** Kratzer, I; Wernig, K; Panzenboeck, U; Bernhart, E; Reicher, H; Wronski, R; Windisch, M; Hammer, A; Malle, E; Zimmer, A; Sattler, W Apolipoprotein A-I coating of protamine-oligonucleotide nanoparticles increases particle uptake and transcytosis in an in vitro model of the blood-brain barrier.
J Control Release. 2007; 117(3): 301-311. Doi: 10.1016/j.jconrel.2006.11.020 [OPEN ACCESS]
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** Marsche, G; Frank, S; Raynes, JG; Kozarsky, KF; Sattler, W; Malle, E The lipidation status of acute-phase protein serum amyloid A determines cholesterol mobilization via scavenger receptor class B, type I.
Biochem J. 2007; 402(1): 117-124. Doi: 10.1042/BJ20061406 [OPEN ACCESS]
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** Marsche, G; Semlitsch, M; Hammer, A; Frank, S; Weigle, B; Demling, N; Schmidt, K; Windischhofer, W; Waeg, G; Sattler, W; Malle, E Hypochlorite-modified albumin colocalizes with RAGE in the artery wall and promotes MCP-1 expression via the RAGE-Erk1/2 MAP-kinase pathway.
FASEB J. 2007; 21(4): 1145-1152. Doi: 10.1096/fj.06-7439com [OPEN ACCESS]
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** Marsche, G; Weigle, B; Sattler, W; Malle, E Soluble RAGE blocks scavenger receptor CD36-mediated uptake of hypochlorite-modified low-density lipoprotein.
FASEB J. 2007; 21(12): 3075-3082. Doi: 10.1096/fj.07-8316com [OPEN ACCESS]
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** Popovic, ZV; Sandhoff, R; Sijmonsma, TP; Kaden, S; Jennemann, R; Kiss, E; Tone, E; Autschbach, F; Platt, N; Malle, E; Gröne, HJ Sulfated glycosphingolipid as mediator of phagocytosis: SM4s enhances apoptotic cell clearance and modulates macrophage activity.
J Immunol. 2007; 179(10): 6770-6782. Doi: 10.4049/jimmunol.179.10.6770 [OPEN ACCESS]
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Review

** Malle, E; Furtmüller, PG; Sattler, W; Obinger, C Myeloperoxidase: a target for new drug development?
Br J Pharmacol. 2007; 152(6): 838-854. Doi: 10.1038/sj.bjp.0707358 [OPEN ACCESS]
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Abstract (Journal)

** Popovic, Z; Sandhoff, R; Sijmonsma, T; Kaden, S; Kiss, E; Tone, E; Malle, F; Autschbach, F; Grone, HJ The role of sulfatide SM4s in apoptotic cell clearance and macrophage function in colon cancer
PATHOL RES PRACT. 2007; 203(5):280-280. [Oral Communication]
Web of Science

 

2006

Full paper/article (Journal)

** Cover, C; Liu, J; Farhood, A; Malle, E; Waalkes, MP; Bajt, ML; Jaeschke, H Pathophysiological role of the acute inflammatory response during acetaminophen hepatotoxicity.
TOXICOL APPL PHARMACOL. 2006; 216(1): 98-107. Doi: 10.1016/j.taap.2006.04.010
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** Kovacevic, A; Hammer, A; Sundl, M; Pfister, B; Hrzenjak, A; Ray, A; Ray, BK; Sattler, W; Malle, E Expression of serum amyloid A transcripts in human trophoblast and fetal-derived trophoblast-like choriocarcinoma cells.
FEBS LETT. 2006; 580(1): 161-167. Doi: 10.1016/j.febslet.2005.11.067 [OPEN ACCESS]
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** Lakio, L; Lehto, M; Tuomainen, AM; Jauhiainen, M; Malle, E; Asikainen, S; Pussinen, PJ Pro-atherogenic properties of lipopolysaccharide from the periodontal pathogen Actinobacillus actinomycetemcomitans.
J ENDOTOXIN RES. 2006; 12(1): 57-64. Doi: 10.1179/096805106X89099
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** Panzenboeck, U; Kratzer, I; Sovic, A; Wintersperger, A; Bernhart, E; Hammer, A; Malle, E; Sattler, W Regulatory effects of synthetic liver X receptor- and peroxisome-proliferator activated receptor agonists on sterol transport pathways in polarized cerebrovascular endothelial cells.
Int J Biochem Cell Biol. 2006; 38(8): 1314-1329. Doi: 10.1016/j.biocel.2006.01.013
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Review

** Malle, E; Marsche, G; Arnhold, J; Davies, MJ Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid.
Biochim Biophys Acta. 2006; 1761(4): 392-415. Doi: 10.1016/j.bbalip.2006.03.024 [OPEN ACCESS]
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** Malle, E; Marsche, G; Panzenboeck, U; Sattler, W Myeloperoxidase-mediated oxidation of high-density lipoproteins: fingerprints of newly recognized potential proatherogenic lipoproteins.
ARCH BIOCHEM BIOPHYS. 2006; 445(2): 245-255. Doi: 10.1016/j.abb.2005.08.008
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2005

Full paper/article (Journal)

** Bräsen, JH; Nieminen-Kelhä, M; Markmann, D; Malle, E; Schneider, W; Neumayer, HH; Budde, K; Luft, FC; Dragun, D Lectin-like oxidized low-density lipoprotein (LDL) receptor (LOX-1)-mediated pathway and vascular oxidative injury in older-age rat renal transplants.
KIDNEY INT. 2005; 67(4): 1583-1594. Doi: 10.1111/j.1523-1755.2005.00240.x [OPEN ACCESS]
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** Hasegawa, T; Malle, E; Farhood, A; Jaeschke, H Generation of hypochlorite-modified proteins by neutrophils during ischemia-reperfusion injury in rat liver: attenuation by ischemic preconditioning.
AMER J PHYSIOL-GASTROINTEST L. 2005; 289(4): G760-G767. Doi: 10.1152/ajpgi.00141.2005 [OPEN ACCESS]
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** Schaefer, L; Babelova, A; Kiss, E; Hausser, HJ; Baliova, M; Krzyzankova, M; Marsche, G; Young, MF; Mihalik, D; Götte, M; Malle, E; Schaefer, RM; Gröne, HJ The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages.
J Clin Invest. 2005; 115(8): 2223-2233. Doi: 10.1172/JCI23755 [OPEN ACCESS]
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** Sovic, A; Panzenboeck, U; Wintersperger, A; Kratzer, I; Hammer, A; Levak-Frank, S; Frank, S; Rader, DJ; Malle, E; Sattler, W Regulated expression of endothelial lipase by porcine brain capillary endothelial cells constituting the blood-brain barrier.
J NEUROCHEM. 2005; 94(1): 109-119. Doi: 10.1111/j.1471-4159.2005.03175.x
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Abstract (Journal)

** Hasegawa, T; Liu, J; Wijeweera, J; Malle, E; Waalkes, MP; Jaeschke, H Augmented hepatic ischemia-reperfusion injury despite reduced inflammation in steatotic livers of ob/ob mice
HEPATOLOGY 2005 42: -.
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2004

Full paper/article (Journal)

** Balazs, Z; Panzenboeck, U; Hammer, A; Sovic, A; Quehenberger, O; Malle, E; Sattler, W Uptake and transport of high-density lipoprotein (HDL) and HDL-associated alpha-tocopherol by an in vitro blood-brain barrier model.
J NEUROCHEM. 2004; 89(4): 939-950. Doi: 10.1111/j.1471-4159.2004.02373.x [OPEN ACCESS]
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** Hrzenjak, A; Reicher, H; Wintersperger, A; Steinecker-Frohnwieser, B; Sedlmayr, P; Schmidt, H; Nakamura, T; Malle, E; Sattler, W Inhibition of lung carcinoma cell growth by high density lipoprotein-associated alpha-tocopheryl-succinate.
CELL MOL LIFE SCI. 2004; 61(12): 1520-1531. Doi: 10.1007/s00018-004-4101-4
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** Marsche, G; Heller, R; Fauler, G; Kovacevic, A; Nuszkowski, A; Graier, W; Sattler, W; Malle, E 2-chlorohexadecanal derived from hypochlorite-modified high-density lipoprotein-associated plasmalogen is a natural inhibitor of endothelial nitric oxide biosynthesis.
ARTERIOSCLER THROMB VASC BIOL. 2004; 24(12): 2302-2306. Doi: 10.1161/01.ATV.0000148703.43429.25 [OPEN ACCESS]
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** Porubsky, S; Schmid, H; Bonrouhi, M; Kretzler, M; Malle, E; Nelson, PJ; Gröne, HJ Influence of native and hypochlorite-modified low-density lipoprotein on gene expression in human proximal tubular epithelium.
AMER J PATHOL. 2004; 164(6): 2175-2187. Doi: 10.1016/S0002-9440(10)63775-3 [OPEN ACCESS]
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** Sovic, A; Balazs, Z; Hrzenjak, A; Reicher, H; Panzenboeck, U; Malle, E; Sattler, W Scavenger receptor class B, type I mediates uptake of lipoprotein-associated phosphatidylcholine by primary porcine cerebrovascular endothelial cells.
NEUROSCI LETT. 2004; 368(1): 11-14. Doi: 10.1016/j.neulet.2004.04.097
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Abstract (Journal)

** Hasegawa, T; Malle, E; Jaeschke, H Generation of neutrophil-derived hypochlorite during ischemia-reperfusion injury in rat liver: Attenuation by ischemic preconditioning.
HEPATOLOGY 2004 40: 377A-377A.
Web of Science

 

** Panzenboeck, U; Sovic, A; Kratzer, I; Hammer, A; Malle, E; Sattler, W Regulation of sterol flux at the blood-brain barrier
ATHEROSCLER SUPPL 2004 5: 73-73.
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2003

Full paper/article (Journal)

** Bräsen, JH; Häkkinen, T; Malle, E; Beisiegel, U; Ylä-Herttuala, S Patterns of oxidized epitopes, but not NF-kappa B expression, change during atherogenesis in WHHL rabbits.
Atherosclerosis. 2003; 166(1):13-21 Doi: 10.1016%2FS0021-9150%2802%2900130-2
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** Egger, T; Schuligoi, R; Wintersperger, A; Amann, R; Malle, E; Sattler, W Vitamin E (alpha-tocopherol) attenuates cyclo-oxygenase 2 transcription and synthesis in immortalized murine BV-2 microglia.
BIOCHEM J 2003 370: 459-467. Doi: 10.1042/BJ20021358 [OPEN ACCESS]
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** Hanumegowda, UM; Copple, BL; Shibuya, M; Malle, E; Ganey, PE; Roth, RA Basement membrane and matrix metalloproteinases in monocrotaline-induced liver injury.
Toxicol Sci. 2003; 76(1):237-246 Doi: 10.1093/toxsci/kfg222 [OPEN ACCESS]
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** Marsche, G; Zimmermann, R; Horiuchi, S; Tandon, NN; Sattler, W; Malle, E Class B scavenger receptors CD36 and SR-BI are receptors for hypochlorite-modified low density lipoprotein.
J Biol Chem. 2003; 278(48):47562-47570 Doi: 10.1074/jbc.M308428200 [OPEN ACCESS]
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** Oettl, K; Höfler, G; Ness, GC; Sattler, W; Malle, E An apparent decrease in cholesterol biosynthesis in peroxisomal-defective Chinese hamster ovary cells is related to impaired mitochondrial oxidation.
BIOCHEM BIOPHYS RES COMMUN. 2003; 305(4): 957-963. Doi: 10.1016%2FS0006-291X%2803%2900855-6
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** Pussinen, PJ; Metso, J; Keva, R; Hirschmugl, B; Sattler, W; Jauhiainen, M; Malle, E Plasma phospholipid transfer protein-mediated reactions are impaired by hypochlorite-modification of high density lipoprotein.
Int J Biochem Cell Biol. 2003; 35(2):192-202 Doi: 10.1016/S1357-2725(02)00130-9
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** Venglarik, CJ; Giron-Calle, J; Wigley, AF; Malle, E; Watanabe, N; Forman, HJ Hypochlorous acid alters bronchial epithelial cell membrane properties and prevention by extracellular glutathione.
J Appl Physiol. 2003; 95(6):2444-2452 Doi: 10.1152/japplphysiol.00002.2003 [OPEN ACCESS]
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** Wadsack, C; Hammer, A; Levak-Frank, S; Desoye, G; Kozarsky, KF; Hirschmugl, B; Sattler, W; Malle, E Selective cholesteryl ester uptake from high density lipoprotein by human first trimester and term villous trophoblast cells.
Placenta. 2003; 24(2-3):131-143 Doi: 10.1053/plac.2002.0912
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** Wadsack, C; Hirschmugl, B; Hammer, A; Levak-Frank, S; Kozarsky, KF; Sattler, W; Malle, E Scavenger receptor class B, type I on non-malignant and malignant human epithelial cells mediates cholesteryl ester-uptake from high density lipoproteins.
Int J Biochem Cell Biol. 2003; 35(4):441-454 Doi: 10.1016/S1357-2725(02)00272-8
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** Wadsack, C; Hrzenjak, A; Hammer, A; Hirschmugl, B; Levak-Frank, S; Desoye, G; Sattler, W; Malle, E Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins.
Eur J Biochem. 2003; 270(3):451-462 Doi: 10.1046%2Fj.1432-1033.2003.03394.x [OPEN ACCESS]
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Review

** Malle, E; Buch, T; Grone, HJ Myeloperoxidase in kidney disease.
Kidney Int. 2003; 64(6):1956-1967 Doi: 10.1046/j.1523-1755.2003.00336.x [OPEN ACCESS]
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** Relou, IA; Hackeng, CM; Akkerman, JW; Malle, E Low-density lipoprotein and its effect on human blood platelets.
Cell Mol Life Sci. 2003; 60(5):961-971 Doi: 10.1007/s00018-003-2249-y
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Abstract (Journal)

** Nelson, PJ; Porubsky, S; Schmid, H; Bonrouhi, M; Kretzler, M; Malle, E; Groene, HJ Influence of native and hypochlorite-modified low density lipoproteins on gene expression in human proximal tubular epithelial cells.
J AMER SOC NEPHROL 2003 14: 375A-375A.
Web of Science

 

2002

Full paper/article (Journal)

** Artl, A; Marsche, G; Pussinen, P; Knipping, G; Sattler, W; Malle, E Impaired capacity of acute-phase high density lipoprotein particles to deliver cholesteryl ester to the human HUH-7 hepatoma cell line.
Int J Biochem Cell Biol. 2002; 34(4):370-381 Doi: 10.1016/S1357-2725(01)00132-7
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** Goti, D; Balazs, Z; Panzenboeck, U; Hrzenjak, A; Reicher, H; Wagner, E; Zechner, R; Malle, E; Sattler, W Effects of lipoprotein lipase on uptake and transcytosis of low density lipoprotein (LDL) and LDL-associated alpha-tocopherol in a porcine in vitro blood-brain barrier model.
J Biol Chem. 2002; 277(32):28537-28544 Doi: 10.1074/jbc.M203989200 [OPEN ACCESS]
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** Gröne, HJ; Gröne, EF; Malle, E Immunohistochemical detection of hypochlorite-modified proteins in glomeruli of human membranous glomerulonephritis.
Lab Invest. 2002; 82(1):5-14 Doi: 10.1038/labinvest.3780390 [OPEN ACCESS]
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** Marsche, G; Hammer, A; Oskolkova, O; Kozarsky, KF; Sattler, W; Malle, E Hypochlorite-modified high density lipoprotein, a high affinity ligand to scavenger receptor class B, type I, impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport.
J Biol Chem. 2002; 277(35):32172-32179 Doi: 10.1074/jbc.M200503200 [OPEN ACCESS]
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** Panzenboeck, U; Balazs, Z; Sovic, A; Hrzenjak, A; Levak-Frank, S; Wintersperger, A; Malle, E; Sattler, W ABCA1 and scavenger receptor class B, type I, are modulators of reverse sterol transport at an in vitro blood-brain barrier constituted of porcine brain capillary endothelial cells.
J Biol Chem. 2002; 277(45):42781-42789 Doi: 10.1074/jbc.M207601200 [OPEN ACCESS]
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Abstract (Journal)

** Wadsack, C; Hammer, A; Levak-Frank, S; Sattler, W; Desoye, G; Malle, E Scavenger receptor class B type I represents an efficient route for supplying cholesterol esters from maternal lipoproteins to developing embryonic tissues
MOL BIOL CELL 2002 13: 640-640.
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2001

Full paper/article (Journal)

** Bergt, C; Marsche, G; Panzenboeck, U; Heinecke, JW; Malle, E; Sattler, W Human neutrophils employ the myeloperoxidase/hydrogen peroxide/chloride system to oxidatively damage apolipoprotein A-I.
Eur J Biochem. 2001; 268(12):3523-3531 Doi: 10.1046%2Fj.1432-1327.2001.02253.x [OPEN ACCESS]
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** Egger, T; Hammer, A; Wintersperger, A; Goti, D; Malle, E; Sattler, W Modulation of microglial superoxide production by alpha-tocopherol in vitro: attenuation of p67(phox) translocation by a protein phosphatase-dependent pathway.
J NEUROCHEM 2001 79: 1169-1182. Doi: 10.1046%2Fj.1471-4159.2001.00641.x [OPEN ACCESS]
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** Goti, D; Hrzenjak, A; Levak-Frank, S; Frank, S; van der Westhuyzen, DR; Malle, E; Sattler, W Scavenger receptor class B, type I is expressed in porcine brain capillary endothelial cells and contributes to selective uptake of HDL-associated vitamin E.
J Neurochem. 2001; 76(2):498-508 Doi: 10.1046%2Fj.1471-4159.2001.00100.x [OPEN ACCESS]
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** Hammer, A; Desoye, G; Dohr, G; Sattler, W; Malle, E Myeloperoxidase-dependent generation of hypochlorite-modified proteins in human placental tissues during normal pregnancy.
LAB INVEST 2001 81: 543-554. Doi: 10.1038/labinvest.3780263 [OPEN ACCESS]
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** Hrzenjak, A; Artl, A; Knipping, G; Kostner, G; Sattler, W; Malle, E Silent mutations in secondary Shine-Dalgarno sequences in the cDNA of human serum amyloid A4 promotes expression of recombinant protein in Escherichia coli.
Protein Eng. 2001; 14(12):949-952 Doi: 10.1093%2Fprotein%2F14.12.949 [OPEN ACCESS]
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** Malle, E; Wäg, G; Thiery, J; Sattler, W; Gröne, HJ Hypochlorite-modified (lipo)proteins are present in rabbit lesions in response to dietary cholesterol.
Biochem Biophys Res Commun. 2001; 289(4):894-900 Doi: 10.1006/bbrc.2001.6074
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** Marsche, G; Levak-Frank, S; Quehenberger, O; Heller, R; Sattler, W; Malle, E Identification of the human analog of SR-BI and LOX-1 as receptors for hypochlorite-modified high density lipoprotein on human umbilical venous endothelial cells.
FASEB J. 2001; 15(6):1095-1097 Doi: 10.1096/fj.00-0532fje [OPEN ACCESS]
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** Nuszkowski, A; Gräbner, R; Marsche, G; Unbehaun, A; Malle, E; Heller, R Hypochlorite-modified low density lipoprotein inhibits nitric oxide synthesis in endothelial cells via an intracellular dislocalization of endothelial nitric-oxide synthase.
J Biol Chem. 2001; 276(17):14212-14221 Doi: 10.1074/jbc.M007659200 [OPEN ACCESS]
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** Pussinen, PJ; Malle, E; Metso, J; Sattler, W; Raynes, JG; Jauhiainen, M Acute-phase HDL in phospholipid transfer protein (PLTP)-mediated HDL conversion.
Atherosclerosis. 2001; 155(2):297-305 Doi: 10.1016%2FS0021-9150%2800%2900568-2
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** Pussinen, PJ; Metso, J; Malle, E; Barlage, S; Palosuo, T; Sattler, W; Schmitz, G; Jauhiainen, M The role of plasma phospholipid transfer protein (PLTP) in HDL remodeling in acute-phase patients.
Biochim Biophys Acta. 2001; 1533(2):153-163 Doi: 10.1016/S1388-1981(01)00153-6
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Abstract (Journal)

** Artl, A; Marsche, G; Pussinen, P; Knipping, G; Sattler, W; Malle, E Impaired capacity of serum amyloid ASAA-enriched acute-phase high-density lipoprotein to deliver cholesteryl ester to human hepatoma cells. A possible role of scavenger receptor class B, type I?
AMYLOID 2001 8: 19-19.
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** Winklhofer-Roob, BM; Sitzwohl, B; Bergmann, AR; Waeg, G; Malle, E; Holzer, H; Roob, JM Oxidative protein modifications in chronic peritoneal dialysis (CAPD) are induced by both 4-hydroxy-2,3-transnonenal and hypochlorite.
FREE RADICAL BIOL MED 2001 31: 275-275.
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2000

Full paper/article (Journal)

** Artl, A; Marsche, G; Lestavel, S; Sattler, W; Malle, E Role of serum amyloid A during metabolism of acute-phase HDL by macrophages.
Arterioscler Thromb Vasc Biol. 2000; 20(3):763-772 Doi: 10.1161/01.ATV.20.3.763 [OPEN ACCESS]
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** Bergt, C; Oettl, K; Keller, W; Andreae, F; Leis, HJ; Malle, E; Sattler, W Reagent or myeloperoxidase-generated hypochlorite affects discrete regions in lipid-free and lipid-associated human apolipoprotein A-I.
Biochem J. 2000; 346 Pt 2(3):345-354 Doi: 10.1042%2F0264-6021%3A3460345 [OPEN ACCESS]
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** Goti, D; Hammer, A; Galla, HJ; Malle, E; Sattler, W Uptake of lipoprotein-associated alpha-tocopherol by primary porcine brain capillary endothelial cells.
J Neurochem. 2000; 74(4):1374-1383 Doi: 10.1046/j.1471-4159.2000.0741374.x [OPEN ACCESS]
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** Malle, E; Waeg, G; Schreiber, R; Gröne, EF; Sattler, W; Gröne, HJ Immunohistochemical evidence for the myeloperoxidase/H2O2/halide system in human atherosclerotic lesions: colocalization of myeloperoxidase and hypochlorite-modified proteins.
Eur J Biochem. 2000; 267(14):4495-4503 Doi: 10.1046%2Fj.1432-1327.2000.01498.x [OPEN ACCESS]
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** Pussinen, PJ; Karten, B; Wintersperger, A; Reicher, H; McLean, M; Malle, E; Sattler, W The human breast carcinoma cell line HBL-100 acquires exogenous cholesterol from high-density lipoprotein via CLA-1 (CD-36 and LIMPII analogous 1)-mediated selective cholesteryl ester uptake.
BIOCHEM J 2000 349: 559-566. Doi: 10.1042%2F0264-6021%3A3490559 [OPEN ACCESS]
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** Pussinen, PJ; Lindner, H; Glatter, O; Reicher, H; Kostner, GM; Wintersperger, A; Malle, E; Sattler, W Lipoprotein-associated alpha-tocopheryl-succinate inhibits cell growth and induces apoptosis in human MCF-7 and HBL-100 breast cancer cells.
BBA-MOL CELL BIOL LIPIDS 2000 1485: 129-144. Doi: 10.1016/S1388-1981(00)00035-4
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** Scheuer, H; Gwinner, W; Hohbach, J; Gröne, EF; Brandes, RP; Malle, E; Olbricht, CJ; Walli, AK; Gröne, HJ Oxidant stress in hyperlipidemia-induced renal damage.
Am J Physiol Renal Physiol. 2000; 278(1):F63-F74 Doi: 10.1152/ajprenal.2000.278.1.F63 [OPEN ACCESS]
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1999

Full paper/article (Journal)

** Bergt, C; Reicher, H; Malle, E; Sattler, W Hypochlorite modification of high density lipoprotein: effects on cholesterol efflux from J774 macrophages.
FEBS Lett. 1999; 452(3):295-300 Doi: 10.1016/S0014-5793(99)00677-8 [OPEN ACCESS]
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** Malle, E Abstracts of papers presented at the XIIIth Platelet Symposium, 22-24 October 1998, Schloss Seggau, Seggauberg, Steiermark, Austria
PLATELETS. 1999; 10(4): 258-271. Doi: 10.1080/09537109976121
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** Malle, E; Leonhard, B; Knipping, G; Sattler, W Effects of cytokines, butyrate and dexamethasone on serum amyloid A and apolipoprotein A-I synthesis in human HUH-7 hepatoma cells.
Scand J Immunol. 1999; 50(2):183-187 Doi: 10.1046%2Fj.1365-3083.1999.00574.x
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** Zabe, M; Feltzer, RE; Malle, E; Sattler, W; Dean, WL Effects of hypochlorite-modified low-density and high-density lipoproteins on intracellular Ca2+ and plasma membrane Ca(2+)-ATPase activity of human platelets.
Cell Calcium. 1999; 26(6):281-287 Doi: 10.1054/ceca.1999.0081
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Abstract (Journal)

** Winklhofer-Roob, BM; Sitzwohl, B; Waeg, G; Steinbrugger, B; Eber, E; Pfleger, A; Oberwaldner, B; Malle, E; Zach, M Immunological evidence of oxidative protein modifications by 4-hydroxynonenal and hypochlorous acid in sputum of patients with cystic fibrosis (CF).
FASEB J. 1999; 13: A701-A701. [Poster]
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1998

Full paper/article (Journal)

** Bíró, L; Domján, G; Falus, A; Jakab, L; Cseh, K; Kalabay, L; Tarkovács, G; Tresch, J; Malle, E; Kramer, J; Prohászka, Z; Jákó, J; Füst, G; Császár, A Cytokine regulation of the acute-phase protein levels in multiple myeloma.
Eur J Clin Invest. 1998; 28(8):679-686 Doi: 10.1046%2Fj.1365-2362.1998.00333.x
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** Goti, D; Reicher, H; Malle, E; Kostner, GM; Panzenboeck, U; Sattler, W High-density lipoprotein (HDL3)-associated alpha-tocopherol is taken up by HepG2 cells via the selective uptake pathway and resecreted with endogenously synthesized apo-lipoprotein B-rich lipoprotein particles.
Biochem J. 1998; 332 ( Pt 1)(3):57-65 Doi: 10.1042/bj3320057 [OPEN ACCESS]
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** Malle, E; Herz, R; Artl, A; Ibovnik, A; Andreae, F; Sattler, W Mapping of antigenic determinants of purified, lipid-free human serum amyloid A proteins.
Scand J Immunol. 1998; 48(5):557-561 Doi: 10.1046%2Fj.1365-3083.1998.00439.x
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** Opper, C; Schüssler, G; Sattler, W; Malle, E Effect of hypochlorite (HOCl)-modified low density lipoproteins and high density lipoproteins on platelet function.
Platelets. 1998; 9(5): 339-341. Doi: 10.1080/09537109876582
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Review

** Sattler, W; Malle, E; Kostner, GM Methodological approaches for assessing lipid and protein oxidation and modification in plasma and isolated lipoproteins.
Methods Mol Biol. 1998; 110: 167-191. Doi: 10.1385/1-59259-582-0:167
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1997

Full paper/article (Journal)

** Knipping, G; Gogg-Fassolter, G; Frohnwieser, B; Krempler, F; Kostner, GM; Malle, E Quantification of apolipoprotein D by an immunoassay with time-resolved fluorescence spectroscopy.
J Immunol Methods. 1997; 202(1):85-95 Doi: 10.1016%2FS0022-1759%2896%2900240-2
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** Malle, E; Bollmann, A; Steinmetz, A; Gemsa, D; Leis, HJ; Sattler, W Serum amyloid A (SAA) protein enhances formation of cyclooxygenase metabolites of activated human monocytes.
FEBS Lett. 1997; 419(2-3):215-219 Doi: 10.1016%2FS0014-5793%2897%2901459-2 [OPEN ACCESS]
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** Malle, E; Woenckhaus, C; Waeg, G; Esterbauer, H; Gröne, EF; Gröne, HJ Immunological evidence for hypochlorite-modified proteins in human kidney.
Am J Pathol. 1997; 150(2):603-615 [OPEN ACCESS]
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** Panzenboeck, U; Raitmayer, S; Reicher, H; Lindner, H; Glatter, O; Malle, E; Sattler, W Effects of reagent and enzymatically generated hypochlorite on physicochemical and metabolic properties of high density lipoproteins.
J Biol Chem. 1997; 272(47):29711-29720 Doi: 10.1074%2Fjbc.272.47.29711 [OPEN ACCESS]
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** Panzenboeck, U; Wintersberger, A; Levak-Frank, S; Zimmermann, R; Zechner, R; Kostner, GM; Malle, E; Sattler, W Implications of endogenous and exogenous lipoprotein lipase for the selective uptake of HDL3-associated cholesteryl esters by mouse peritoneal macrophages.
J Lipid Res. 1997; 38(2):239-253 Doi: 10.1016/S0022-2275(20)37437-X [OPEN ACCESS]
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** Schorsch, F; Malle, E; Sattler, W Selective uptake of high density lipoprotein-associated cholesterylesters by differentiated Ob1771 adipocytes is modulated by endogenous and exogenous lipoprotein lipase.
FEBS Lett. 1997; 414(3):507-513 Doi: 10.1016%2FS0014-5793%2897%2901061-2 [OPEN ACCESS]
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Abstract (Journal)

** Grone, EF; Malle, E; Stocker, R; Grone, HJ Hypochlorite-modified proteins in glomeruli of human membranous glomerulonephritis.
J AMER SOC NEPHROL 1997 8: A2494-A2494.
Web of Science

 

** Gwinner, W; Scheuer, H; Hohbach, J; Olbricht, CJ; Malle, E; Grone, HJ Effect of hyperlipidemia on renal oxidative and antioxidative enzymes in rats with and without mesangioproliferative glomerulonephritis.
J AMER SOC NEPHROL 1997 8: A2875-A2875.
Web of Science

 

** Sattler, W; Raitmayer, S; Kostner, G; Malle, E; Panzenboeck, U Effects of hypochlorite-modification on physico-chemical and biological properties of high density lipoproteins
ATHEROSCLEROSIS 1997 134: 373-373. Doi: 10.1016/S0021-9150(97)89893-0
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1996

Full paper/article (Journal)

** Hazell, LJ; Arnold, L; Flowers, D; Waeg, G; Malle, E; Stocker, R Presence of hypochlorite-modified proteins in human atherosclerotic lesions.
J Clin Invest. 1996; 97(6):1535-1544 Doi: 10.1172/JCI118576 [OPEN ACCESS]
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** Malle, E; Pfeiffer, KP; Dugi, K; Pfeiffer, C; Glaum, M; Oezcueruemez, M; Kloer, HU; Steinmetz, A Polymorphisms of apolipoproteins A-IV and E in a Turkish population living in Germany.
Hum Genet. 1996; 98(3):285-290 Doi: 10.1007%2Fs004390050208
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** Oettl, K; Malle, E; Grillhofer, H; Sattler, W; Kostner, GM Cholesterol metabolism in cells with different peroxisomal defects.
Clin Chim Acta. 1996; 251(2):131-143 Doi: 10.1016%2F0009-8981%2896%2906301-2
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** Sattler, W; Reicher, H; Ramos, P; Panzenboeck, U; Hayn, M; Esterbauer, H; Malle, E; Kostner, GM Preparation of fatty acid methyl esters from lipoprotein and macrophage lipid subclasses on thin-layer plates.
Lipids. 1996; 31(12):1302-1310 Doi: 10.1007/BF02587917
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** Wicher, I; Sattler, W; Ibovnik, A; Kostner, GM; Zechner, R; Malle, E Quantification of lipoprotein lipase (LPL) by dissociation-enhanced lanthanide fluorescence immunoassay. Comparison of immunoreactivity of LPL mass and enzyme activity of LPL.
J Immunol Methods. 1996; 192(1-2):1-11 Doi: 10.1016%2F0022-1759%2895%2900260-X
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Review

** Malle, E; De Beer, FC Human serum amyloid A (SAA) protein: a prominent acute-phase reactant for clinical practice.
Eur J Clin Invest. 1996; 26(6):427-435 Doi: 10.1046%2Fj.1365-2362.1996.159291.x
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1995

Full paper/article (Journal)

** Malle, E; Hazell, L; Stocker, R; Sattler, W; Esterbauer, H; Waeg, G Immunologic detection and measurement of hypochlorite-modified LDL with specific monoclonal antibodies.
Arterioscler Thromb Vasc Biol. 1995; 15(7):982-989 Doi: 10.1161/01.ATV.15.7.982 [OPEN ACCESS]
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** Malle, E; Ibovnik, A; Leis, HJ; Kostner, GM; Verhallen, PF; Sattler, W Lysine modification of LDL or lipoprotein(a) by 4-hydroxynonenal or malondialdehyde decreases platelet serotonin secretion without affecting platelet aggregability and eicosanoid formation.
Arterioscler Thromb Vasc Biol. 1995; 15(3):377-384 Doi: 10.1161/01.ATV.15.3.377 [OPEN ACCESS]
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** Malle, E; Münscher, G; Müller, T; Vermeer, H; Ibovnik, A Quantification and mapping of antigenic determinants of serum amyloid A (SAA) protein utilizing sequence-specific immunoglobulins and Eu3+ as a specific probe for time-resolved fluorometric immunoassay.
J Immunol Methods. 1995; 182(1):131-144 Doi: 10.1016%2F0022-1759%2895%2900035-9
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** Malle, E; Oettl, K; Sattler, W; Hoefler, G; Kostner, GM Cholesterol biosynthesis in dermal fibroblasts from patients with metabolic disorders of peroxisomal origin.
Eur J Clin Invest. 1995; 25(1):59-67 Doi: 10.1111/j.1365-2362.1995.tb01527.x [OPEN ACCESS]
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** Sattler, W; Leis, HJ; Kostner, GM; Malle, E Quantification of 7-dehydrocholesterol in plasma and amniotic fluid by liquid chromatography/particle beam-mass spectrometry as a biochemical diagnostic marker for the Smith-Lemli-Opitz syndrome.
Rapid Commun Mass Spectrom. 1995; 9(13):1288-1292 Doi: 10.1002/rcm.1290091313
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Abstract (Journal)

** WOENCKHAUS, C; GRONE, HJ; MALLE, E; SPRENGER, H; WAEG, G HYPOCHLOROUS ACID MODIFIED PROTEINS - LOCALIZATION IN HUMAN KIDNEYS AND EFFECT ON HUMAN MONOCYTES
J AMER SOC NEPHROL 1995 6: 1035-1035.
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1994

Full paper/article (Journal)

** Malle, E; Ibovnik, A; Stienmetz, A; Kostner, GM; Sattler, W Identification of glycoprotein IIb as the lipoprotein(a)-binding protein on platelets. Lipoprotein(a) binding is independent of an arginyl-glycyl-aspartate tripeptide located in apolipoprotein(a).
Arterioscler Thromb. 1994; 14(3):345-352 Doi: 10.1161/01.ATV.14.3.345 [OPEN ACCESS]
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** Malle, E; Schwengerer, E; Paltauf, F; Hermetter, A Transfer of pyrene-labelled diacyl-, alkylacyl-, and alkenylacyl-glycerophospholipids from vesicles to human blood platelets.
BBA, BIOMEMBRANES. 1994; 1189(1): 61-64. Doi: 10.1016/0005-2736(94)90280-1
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Review

** MALLE, E; SATTLER, W PLATELETS AND THE LIPOPROTEINS - NATIVE, MODIFIED AND PLATELET MODIFIED LIPOPROTEINS
PLATELETS. 1994; 5(2): 70-83. Doi: 10.3109/09537109409005516
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1993

Review

** Malle, E; Kostner, GM Effects of fish oils on lipid variables and platelet function indices.
Prostaglandins Leukot Essent Fatty Acids. 1993; 49(3):645-663 Doi: 10.1016%2F0952-3278%2893%2990074-7
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** Malle, E; Steinmetz, A; Raynes, JG Serum amyloid A (SAA): an acute phase protein and apolipoprotein.
ATHEROSCLEROSIS. 1993; 102(2): 131-146. Doi: 10.1016/0021-9150(93)90155-N
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Note

** Mache, CJ; Schwingshandl, J; Riccabona, M; Ranner, G; Ring, E; Fock, C; Ratschek, M; Malle, E; Borkenstein, MH Ultrasound and MRI findings in a case of childhood amyloid goiter.
Pediatr Radiol. 1993; 23(7):565-566 Doi: 10.1007/BF02012155 (- Case Report)
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** Malle, E; Leis, HJ; Steinmetz, A; Paschke, E; Hoefler, G Cyclooxygenase pathway in dermal fibroblasts from patients with metabolic disorders of peroxisomal origin.
CLIN CHIM ACTA. 1993; 217(2): 205-212. Doi: 10.1016/0009-8981(93)90167-3
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1992

Full paper/article (Journal)

** Malle, E; Hess, H; Münscher, G; Knipping, G; Steinmetz, A Purification of serum amyloid A and its isoforms from human plasma by hydrophobic interaction chromatography and preparative isoelectric focusing.
Electrophoresis. 1992; 13(7):422-428 Doi: 10.1002/elps.1150130189
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1991

Full paper/article (Journal)

** Kluve-Beckerman, B; Malle, E; Vitt, H; Pfeiffer, C; Benson, M; Steinmetz, A Characterization of an isoelectric focusing variant of SAA1 (ASP-72) in a family of Turkish origin.
Biochem Biophys Res Commun. 1991; 181(3): 1097-1102. Doi: 10.1016/0006-291X(91)92051-K
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** Leis, HJ; Malle, E Deuterium-labelling and quantitative measurement of ketotifen in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry.
Biol Mass Spectrom. 1991; 20(8):467-470 Doi: 10.1002/bms.1200200806
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** Malle, E; Sattler, W; Prenner, E; Leis, HJ; Hermetter, A; Gries, A; Kostner, GM Effects of dietary fish oil supplementation on platelet aggregability and platelet membrane fluidity in normolipemic subjects with and without high plasma Lp(a) concentrations.
Atherosclerosis. 1991; 88(2-3):193-201 Doi: 10.1016/0021-9150(91)90081-D
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** Malle, E; Sattler, W; Prenner, E; Leis, HJ; Karàdi, I; Knipping, G; Romics, L; Kostner, GM Platelet membrane fluidity in type IIA, type IIB and type IV hyperlipoproteinemia.
Atherosclerosis. 1991; 87(2-3):159-167 Doi: 10.1016/0021-9150(91)90018-X
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1990

Full paper/article (Journal)

** Leis, HJ; Gleispach, H; Nitsche, V; Malle, E Quantitative determination of terbutaline and orciprenaline in human plasma by gas chromatography/negative ion chemical ionization/mass spectrometry.
Biomed Environ Mass Spectrom. 1990; 19(6):382-386 Doi: 10.1002/bms.1200190609
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** Leis, HJ; Leis, M; Welz, W; Malle, E Determination of captopril in human blood by gas chromatography-negative-ion chemical ionization mass spectrometry with 18O4captopril as internal standard.
J Chromatogr. 1990; 529(2):299-308 Doi: 10.1016/S0378-4347(00)83836-0
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** Leis, HJ; Malle, E; Hoffmann, O; Klaushofer, K; Fratzl-Zelman, N; Koller, K; Peterlik, M Experimental considerations on the measurement of prostaglandins during long-time incubations of neonatal mouse calvaria.
Biochem Biophys Res Commun. 1990; 169(2):545-550 Doi: 10.1016/0006-291X(90)90365-T
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** MALLE, E; STADLBAUER, W; OSTERMANN, G; HOFMANN, B; LEIS, HJ; KOSTNER, GM ORGANIC AZIDES IN HETEROCYCLIC SYNTHESIS .10. SYNTHESIS OF NEW 2-SUBSTITUTED, 3-SUBSTITUTED, AND 4-SUBSTITUTED AZIDOQUINOLINES - INHIBITORS OF HUMAN BLOOD-PLATELET AGGREGATION INVITRO
EUR J MED CHEM. 1990; 25: 137-142. Doi: 10.1016/0223-5234(90)90022-U
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** Welz, W; Sattler, W; Leis, HJ; Malle, E Rapid analysis of non-esterified fatty acids as methyl esters from different biological specimens by gas chromatography after one-step esterification.
J Chromatogr. 1990; 526(2):319-329 Doi: 10.1016/S0378-4347(00)82516-5
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Short report/Letter

** Gries, A; Malle, E; Wurm, H; Kostner, GM Influence of dietary fish oils on plasma Lp(a) levels.
Thromb Res. 1990; 58(6):667-668 Doi: 10.1016/0049-3848(90)90314-3
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Note

** Leis, HJ; Welz, W; Malle, E 11-Dehydrothromboxane B2: convenient preparation of its stable isotope-labelled analogue for use in quantitative gas chromatography-mass spectrometry.
J CHROMATOGR-BIOMED APPL. 1990; 526(1): 169-173. Doi: 10.1016/S0378-4347(00)82494-9
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** MALLE, E; NIMPF, J; LEIS, HJ; WURM, H; KOSTNER, GM POSTPRANDIAL HYPERLIPEMIA AND PLATELET EICOSANOID METABOLISM
KLIN WOCHENSCHR. 1990; 68: 116-116.
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1989

Full paper/article (Journal)

** Malle, E; Gleispach, H; Kostner, GM; Leis, HJ Isotope dilution gas chromatography-mass spectrometry for the study of eicosanoid metabolism in human blood platelets.
J Chromatogr. 1989; 488(1):283-293 Doi: 10.1016/S0378-4347(00)82953-9
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** Malle, E; Gries, A; Kostner, GM; Pfeiffer, K; Nimpf, J; Hermetter, A Is there any correlation between platelet aggregation, plasma lipoproteins, apoproteins and membrane fluidity of human blood platelets?
Thromb Res. 1989; 53(2):181-190 Doi: 10.1016/0049-3848(89)90378-2
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** Malle, E; Rotheneder, M; Vetterlein, M; Kostner, GM Influence of morphology and malignancy of three new human melanoma cell lines on the cyclooxygenase pathway.
PROSTAGLANDINS 1989 37: 389-398. Doi: 10.1016/0090-6980(89)90009-9
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** Nimpf, J; Malle, E; Leopold, B; Wurm, H; Kostner, GM Postprandial hyperlipemia inhibits platelet aggregation without affecting prostanoid metabolism.
Prostaglandins Leukot Essent Fatty Acids. 1989; 37(1):7-13 Doi: 10.1016/0952-3278(89)90179-8
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** Ostermann, G; Kostner, GM; Gries, A; Malle, E; Till, U The contribution of individual lipoproteins to the degradation of platelet-activating factor in human serum.
Haemostasis. 1989; 19(3):160-168 Doi: 10.1159/000215910
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1988

Full paper/article (Journal)

** Karàdi, I; Kostner, GM; Gries, A; Nimpf, J; Romics, L; Malle, E Lipoprotein (a) and plasminogen are immunochemically related.
Biochim Biophys Acta. 1988; 960(1):91-97 Doi: 10.1016/0005-2760(88)90013-6
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** Leis, HJ; Gleispach, H; Malle, E A convenient route to stable-isotope-labelled compounds for use in quantitative gas chromatography/mass spectrometry.
Rapid Commun Mass Spectrom. 1988; 2(12): 263-265. Doi: 10.1002/rcm.1290021202
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** Leis, HJ; Gleispach, H; Malle, E; Nitsche, V Femtomole analysis of diclofenac in human plasma by gas chromatography/negative ion chemical ionization/mass spectrometry using (18O2)diclofenac as internal standard.
BIOMED ENVIRON MASS SPECTROM. 1988; 17(4): 307-310. Doi: 10.1002/bms.1200170414
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** Leis, HJ; Gleispach, H; Nitsche, V; Malle, E Femtomole analysis of diclofenac in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry using (18O2) diclofenac as internal standard.
BIOMED ENVIRON MASS SPECTROM. 1988; 17(6): 437-441. Doi: 10.1002/bms.1200170604
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Abstract (Journal)

** GLEISPACH, H; MALLE, E; LEIS, HJ ISOTOPE-DILUTION GAS CHROMATOGRAPHY-MASS SPECTROMETRY FOR THE STUDY OF THE EICOSANOID METABOLISM
ANN BIOL CLIN PARIS. 1988; 46(7): 505-505.
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** GLEISPACH, H; MALLE, E; LEIS, HJ ISOTOPE-DILUTION GAS CHROMATOGRAPHY-MASS SPECTROMETRY FOR THE STUDY OF THE EICOSANOID METABOLISM
ANN BIOL CLIN PARIS. 1988; 46(7): 504-504.
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1987

Full paper/article (Journal)

** Leis, HJ; Hohenester, E; Gleispach, H; Malle, E; Mayer, B Measurement of prostaglandins, thromboxanes and hydroxy fatty acids by stable isotope dilution gas chromatography/mass spectrometry.
Biomed Environ Mass Spectrom. 1987; 14(11):617-621 Doi: 10.1002/bms.1200141108
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** Leis, HJ; Malle, E; Mayer, B; Kostner, GM; Esterbauer, H; Gleispach, H Quantitative measurement of 5-, 12-, and 15-hydroxyeicosatetraenoic acid together with 12-hydroxyheptadecatrienoic acid by stable isotope dilution gas chromatography-negative ion chemical ionization-mass spectrometry.
Anal Biochem. 1987; 162(2):337-344 Doi: 10.1016/0003-2697(87)90401-5
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** Malle, E; Leis, HJ; Palm, W Comparative studies on partial microsequence-analysis of Bence-Jones proteins.
Int J Biochem. 1987; 19(9):853-856 Doi: 10.1016/0020-711X(87)90245-X
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** Malle, E; Nimpf, J; Leis, HJ; Wurm, H; Gleispach, H; Kostner, GM Cyclooxygenase and lipoxygenase metabolites during platelet aggregation: quantitative measurement by negative ion chemical ionization--gas chromatography/mass spectrometry.
Prostaglandins Leukot Med. 1987; 27(1):53-70 Doi: 10.1016/0262-1746(87)90059-X
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** NIMPF, J; MALLE, E; WURM, H; KOSTNER, GM IS THERE ANY CORRELATION BETWEEN PLATELET ACTIVATION AND PLASMA-LIPOPROTEINS
AGENT ACTION 1987 22: 366-368. Doi: 10.1007/BF02009081
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Review

** Malle, E; Leis, HJ; Karádi, I; Kostner, GM Lipoxygenases and hydroperoxy/hydroxy-eicosatetraenoic acid formation.
Int J Biochem. 1987; 19(11):1013-1022 Doi: 10.1016/0020-711X(87)90301-6
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1986

Full paper/article (Journal)

** LEIS, HJ; MALLE, E; MOSER, R; NIMPF, J; KOSTNER, GM; ESTERBAUER, H; GLEISPACH, H Preparation of 18O-labelled standards of hydroxy-eicosatetraenoic acids and thromboxanes for quantitative measurement by gas chromatography/mass spectrometry.
Biomed Environ Mass Spectrom. 1986; 13(9):483-488 Doi: 10.1002/bms.1200130906
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