** = Publications listed in SCI/SSCI/Pubmed
** Ding, Y; Yuan, XL; Wang, YC; Wang, AY; Shi, X; Wang, L; Litscher, D; Gaischek, I; Lippe, IT; Litscher, G
Acupotomy versus sodium hyaluronate for treatment of knee osteoarthritis in rabbits
J TRADIT CHIN MED. 2017; 37(3): 404-411.
Doi: 10.1016/S0254-6272(17)30078-X
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** Yang, J; Litscher, G; Sun, Z; Tang, Q; Kishi, K; Oda, S; Takayanagi, M; Sheng, Z; Liu, Y; Guo, W; Zhang, T; Wang, L; Gaischek, I; Litscher, D; Lippe, IT; Kuroda, M
Quantitative analysis of axon collaterals of single pyramidal cells of the anterior piriform cortex of the guinea pig.
BMC Neurosci. 2017; 18(1):25-25
Doi: 10.1186/s12868-017-0342-7
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** Wang, JY; Chen, R; Chen, SP; Gao, YH; Zhang, JL; Feng, XM; Yan, Y; Liu, JL; Gaischek, I; Litscher, D; Wang, L; Lippe, IT; Litscher, G
Electroacupuncture Reduces the Effects of Acute Noxious Stimulation on the Electrical Activity of Pain-Related Neurons in the Hippocampus of Control and Neuropathic Pain Rats.
Neural Plast. 2016; 2016(51):6521026-6521026
Doi: 10.1155/2016/6521026
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** Konya, V; Maric, J; Jandl, K; Luschnig, P; Aringer, I; Lanz, I; Platzer, W; Theiler, A; Bärnthaler, T; Frei, R; Marsche, G; Marsh, LM; Olschewski, A; Lippe, IT; Heinemann, A; Schuligoi, R
Activation of EP4 receptors prevents endotoxin-induced neutrophil infiltration into the airways and enhances microvascular barrier function.
Br J Pharmacol. 2015; 172(18):4454-4468
Doi: 10.1111/bph.13229
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** Sturm, EM; Parzmair, GP; Radnai, B; Frei, RB; Sturm, GJ; Hammer, A; Schuligoi, R; Lippe, IT; Heinemann, A
Phosphoinositide-dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils.
Eur J Immunol. 2015; 45(5):1548-1559
Doi: 10.1002/eji.201445196
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** Luschnig, P; Frei, R; Lang-Loidolt, D; Rozsasi, A; Tomazic, PV; Lippe, IT; Schuligoi, R; Heinemann, A
Altered inhibitory function of the E-type prostanoid receptor 4 in eosinophils and monocytes from aspirin-intolerant patients.
Pharmacology. 2014; 94(5-6):280-286
Doi: 10.1159/000369827
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** Luschnig-Schratl, P; Sturm, EM; Konya, V; Philipose, S; Marsche, G; Fröhlich, E; Samberger, C; Lang-Loidolt, D; Gattenlöhner, S; Lippe, IT; Peskar, BA; Schuligoi, R; Heinemann, A
EP4 receptor stimulation down-regulates human eosinophil function.
Cell Mol Life Sci. 2011; 68(21): 3573-3587.
Doi: 10.1007/s00018-011-0642-5
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** Joainig, MM; Gorkiewicz, G; Leitner, E; Weberhofer, P; Zollner-Schwetz, I; Lippe, I; Feierl, G; Krause, R; Hinterleitner, T; Zechner, EL; Högenauer, C
Cytotoxic effects of Klebsiella oxytoca strains isolated from patients with antibiotic-associated hemorrhagic colitis or other diseases caused by infections and from healthy subjects.
J Clin Microbiol. 2010; 48(3):817-824
Doi: 10.1128/JCM.01741-09
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** Konya, V; Sturm, EM; Schratl, P; Beubler, E; Marsche, G; Schuligoi, R; Lippe, IT; Peskar, BA; Heinemann, A
Endothelium-derived prostaglandin I(2) controls the migration of eosinophils.
J Allergy Clin Immunol. 2010; 125(5): 1105-1113.
Doi: 10.1016/j.jaci.2009.12.002
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** Philipose, S; Konya, V; Sreckovic, I; Marsche, G; Lippe, IT; Peskar, BA; Heinemann, A; Schuligoi, R
The Prostaglandin E2 Receptor EP4 Is Expressed by Human Platelets and Potently Inhibits Platelet Aggregation and Thrombus Formation.
Arterioscler Thromb Vasc Biol. 2010; 30(12): 2416-2423.
Doi: 10.1161/ATVBAHA.110.216374
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** Heinemann, A; Schuligoi, R; Lippe, IT; Stauber, RE
Restriction of drinking water abrogates splanchnic vasodilation and portal hypertension in portal vein-ligated rats.
Pharmacology. 2009; 83(1): 26-32.
Doi: 10.1159/000167877
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** Schuligoi, R; Sedej, M; Waldhoer, M; Vukoja, A; Sturm, EM; Lippe, IT; Peskar, BA; Heinemann, A
Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2.
J Leukoc Biol. 2009; 85(1): 136-145.
Doi: 10.1189/jlb.0608387
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** Sturm, EM; Schratl, P; Schuligoi, R; Konya, V; Sturm, GJ; Lippe, IT; Peskar, BA; Heinemann, A
Prostaglandin E2 inhibits eosinophil trafficking through E-prostanoid 2 receptors.
J Immunol. 2008; 181(10): 7273-7283.
Doi: 10.4049/jimmunol.181.10.7273
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** Schratl, P; Royer, JF; Kostenis, E; Ulven, T; Sturm, EM; Waldhoer, M; Hoefler, G; Schuligoi, R; Lippe, IT; Peskar, BA; Heinemann, A
The role of the prostaglandin D2 receptor, DP, in eosinophil trafficking.
J Immunol. 2007; 179(7):4792-4799
Doi: 10.4049/jimmunol.179.7.4792
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** Högenauer, C; Langner, C; Beubler, E; Lippe, IT; Schicho, R; Gorkiewicz, G; Krause, R; Gerstgrasser, N; Krejs, GJ; Hinterleitner, TA
Klebsiella oxytoca as a causative organism of antibiotic-associated hemorrhagic colitis.
N Engl J Med. 2006; 355(23):2418-2426
Doi: 10.1056/NEJMoa054765
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** Schratl, P; Sturm, EM; Royer, JF; Sturm, GJ; Lippe, IT; Peskar, BA; Heinemann, A
Hierarchy of eosinophil chemoattractants: role of p38 mitogen-activated protein kinase.
EUR J IMMUNOL. 2006; 36(9): 2401-2409.
Doi: 10.1002/eji.200535672
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** Schratl, P; Royer, JF; Kostenis, E; Sturm, EM; Schuligoi, R; Lippe, IT; Peskar, BA; Heinemann, A
Role of the prostaglandin D 2 receptors, CRTH2 and DP, in eosinophil chemotaxis and mobilization from bone marrow
PHARMACOLOGY. 2006; 78(3):149-149.
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** Schicho, R; Donnerer, J; Liebmann, I; Lippe, IT
Nociceptive transmitter release in the dorsal spinal cord by capsaicin-sensitive fibers after noxious gastric stimulation.
BRAIN RES. 2005; 1039(1-2): 108-115.
Doi: 10.1016/j.brainres.2005.01.050
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** Schicho, R; Liebmann, I; Lippe, IT
Extracellular signal-regulated kinase-1 and -2 are activated by gastric luminal injury in dorsal root ganglion neurons via N-methyl-D-aspartate receptors.
NEUROSCIENCE. 2005; 134(2): 505-514.
Doi: 10.1016/j.neuroscience.2005.04.021
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** Danzer, M; Jocic, M; Samberger, C; Painsipp, E; Bock, E; Pabst, MA; Crailsheim, K; Schicho, R; Lippe, IT; Holzer, P
Stomach-brain communication by vagal afferents in response to luminal acid backdiffusion, gastrin, and gastric acid secretion.
AMER J PHYSIOL-GASTROINTEST L. 2004; 286(3): G403-G411.
Doi: 10.1152/ajpgi.00308.2003
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** Danzer, M; Samberger, C; Schicho, R; Lippe, IT; Holzer, P
Immunocytochemical characterization of rat brainstem neurons with vagal afferent input from the stomach challenged by acid or ammonia.
Eur J Neurosci. 2004; 19(1):85-92
Doi: 10.1111/j.1460-9568.2004.03109.x
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** Holzer, P; Danzer, M; Schicho, R; Samberger, C; Painsipp, E; Lippe, IT
Vagal afferent input from the acid-challenged rat stomach to the brainstem: enhancement by interleukin-1beta.
NEUROSCIENCE. 2004; 129(2): 439-445.
Doi: 10.1016/j.neuroscience.2004.07.040
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** Schicho, R; Florian, W; Liebmann, I; Holzer, P; Lippe, IT
Increased expression of TRPV1 receptor in dorsal root ganglia by acid insult of the rat gastric mucosa.
EUR J NEUROSCI. 2004; 19(7): 1811-1818.
Doi: 10.1111/j.1460-9568.2004.03290.x
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** Schicho, R; Holzer, P; Lippe, IT
Gastric enteric neurones that respond to luminal injury.
NEUROGASTROENTEROL MOTIL. 2004; 16 Suppl 1(7): 129-132.
Doi: 10.1111/j.1743-3150.2004.00488.x
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** Hoegenauer, C; Langner, C; Beubler, E; Lippe, ITH; Schicho, R; Krejs, GJ; Hinterleitner, TA
Antibiotic-associated hemorrhagic colitis is induced by Klebsiella oxytoca in an in vivo rat model
GASTROENTEROLOGY. 2004; 126(4): A251-A252.
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** Schicho, R; Holzer, P; Lippe, IT
Increased TRPV1 expression in dorsal root ganglia (DRG) after acid insult of the rat stomach
PHARMACOLOGY 2004 72: 135-136.
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** Schicho, R; Schemann, M; Pabst, MA; Holzer, P; Lippe, IT
Capsaicin-sensitive extrinsic afferents are involved in acid-induced activation of distinct myenteric neurons in the rat stomach.
Neurogastroenterol Motil. 2003; 15(1):33-44
Doi: 10.1046%2Fj.1365-2982.2003.00384.x
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** Holzer, P; Danzer, M; Samberger, C; Schicho, R; Lippe, IT
Three mechanisms of gut-brain communication induced by peripheral pentagastrin: Acid- and Cck1 receptor-mediated stimulation of vagal afferents and Cck2 receptor-mediated stimulation of area postrema neurons
GASTROENTEROLOGY. 2003; 124(4): A116-A116.
Doi: 10.1016/S0016-5085(03)80570-X
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** Danzer, M; Schicho, R; Lippe, I; Holzer, P
Interleukin-1 beta-induced sensitization of vagal afferent pathways to intragastric acid challenge: A novel experimental model of functional dyspepsia?
GASTROENTEROLOGY. 2002; 122(4): A34-A34.
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** Danzer, M; Schicho, R; Lippe, I; Holzer, P
Identical chemical coding of brainstem neurons that respond to afferent input from the acid- and ammonia-challenged rat gastric mucosa
GASTROENTEROLOGY. 2002; 122(4): A383-A383.
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** Lippe, IT; Schicho, R; Holzer, P
Involvement of ganglionic transmission via nicotinic receptors and capsaicin-sensitive afferents in acid-induced activation of rat gastric myenteric neurons
NAUNYN-SCHMIED ARCH PHARMACOL 2002 365: R101-R101.
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** Schicho, R; Danzer, M; Holzer, P; Lippe, I
Acid-induced activation of rat gastric myenteric neurons involves capsaicin-sensitive afferents and ganglionic transmission via nicotinic receptors
GASTROENTEROLOGY. 2002; 122(4): A561-A561.
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** Schicho, R; Danzer, M; Pabst, MA; Holzer, P; Lippe, I
Neurochemical and confocal microscopic analysis reveals that acid-activated nitrergic neurons of the rat gastric myenteric plexus are inhibitory motor neurons
GASTROENTEROLOGY. 2002; 122(4): A92-A92.
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** Schicho, R; Schemann, M; Holzer, P; Lippe, IT
Mucosal acid challenge activates nitrergic neurons in myenteric plexus of rat stomach.
Am J Physiol Gastrointest Liver Physiol. 2001; 281(5):G1316-G1321
Doi: 10.1152/ajpgi.2001.281.5.G1316
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** Holzer, P; Michl, T; Danzer, M; Jocic, M; Schicho, R; Lippe, IT
Surveillance of the gastrointestinal mucosa by sensory neurons.
J Physiol Pharmacol. 2001; 52(4 Pt 1):505-521
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** Holzer, P; Schicho, R; Holzer-Petsche, U; Lippe, IT
The gut as a neurological organ.
Wien Klin Wochenschr. 2001; 113(17-18):647-660
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** Lippe, IT; Brodacz, B; Holzer, P
Gastric vasodilatation in the rat by cannabinoid (CB) receptor activation: Involvement of sensory neurons and nitric oxide (NO).
GASTROENTEROLOGY 2000 118: 4365-4365.
Doi: 10.1016/S0016-5085(00)85453-0
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** Lippe, IT; Wascher-Hartmann, B; Brodacz, B; Holzer, P
Noxious acid concentrations stimulate enteric neurons in the rat stomach.
GASTROENTEROLOGY 2000 118: A1186-A1186.
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** Holzer, P; Lippe, IT; Heinemann, A; Barthó, L
Tachykinin NK1 and NK2 receptor-mediated control of peristaltic propulsion in the guinea-pig small intestine in vitro.
Neuropharmacology. 1998; 37(1):131-138
Doi: 10.1016%2FS0028-3908%2897%2900195-0
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** Holzer, P; Lippe, IT; Tabrizi, AL; Lènárd, L; Barthó, L
Dual excitatory and inhibitory effect of nitric oxide on peristalsis in the guinea pig intestine.
J Pharmacol Exp Ther. 1997; 280(1):154-161
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** Lippe, I; Wachter, CH; Holzer, P
Neurokinin A-induced vasoconstriction and muscular contraction in the rat isolated stomach: mediation by distinct and unusual neurokinin2 receptors.
J Pharmacol Exp Ther. 1997; 281(3):1294-1302
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** Holzer, P; Lippe, IT
Inhibition of intestinal peristalsis caused by substance P involves nitric oxide.
GASTROENTEROLOGY 1997 112: A750-A750.
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** Holzer, P; Lippe, IT
Implication of nitric oxide in the substance P NK1 receptor-mediated inhibition of guinea-pig intestinal peristalsis
NAUNYN-SCHMIED ARCH PHARMACOL 1997 356: 131-131.
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** Lippe, IT; Holzer, P
Tachykinins regulate intestinal peristalsis via NK1 and NK2, but not NK3, receptors.
GASTROENTEROLOGY 1997 112: A777-A777.
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** Holzer, P; Wachter, C; Heinemann, A; Jocic, M; Lippe, IT; Herbert, MK
Diverse interactions of calcitonin gene related peptide and nitric oxide in the gastric and cutaneous microcirculation.
CAN J PHYSIOL PHARMACOL. 1995; 73(7): 991-994.
Doi: 10.1139/y95-138
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** Holzer, P; Wachter, C; Heinemann, A; Jocic, M; Lippe, IT; Herbert, MK
Sensory nerves, nitric oxide and NANC vasodilatation.
Arch Int Pharmacodyn Ther. 1995; 329(1):67-79
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** Battistel, M; Plebani, M; Di Mario, F; Jocic, M; Lippe, IT; Holzer, P
Chronic nicotine intake causes vascular dysregulation in the rat gastric mucosa.
Gut. 1993; 34(12):1688-1692
Doi: 10.1007%2FBF00169837
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** Giuliani, S; Santicioli, P; Lippe, IT; Lecci, A; Maggi, CA
Effect of bradykinin and tachykinin receptor antagonist on xylene-induced cystitis in rats.
J Urol. 1993; 150(3):1014-1017
Doi: 10.1016/S0022-5347(17)35677-X
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** Holzer, P; Lippe, IT; Jocic, M; Wachter, C; Erb, R; Heinemann, A
Nitric oxide-dependent and -independent hyperaemia due to calcitonin gene-related peptide in the rat stomach.
Br J Pharmacol. 1993; 110(1):404-410
Doi: 10.1111/j.1476-5381.1993.tb13824.x
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** Lippe, IT; Sametz, W; Sabin, K; Holzer, P
Inhibitory role of capsaicin-sensitive afferent neurons and nitric oxide in hemostasis.
Am J Physiol. 1993; 265(6 Pt 2):H1864-H1868
Doi: 10.1152/ajpheart.1993.265.6.H1864
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** Lippe, IT; Stabentheiner, A; Holzer, P
Participation of nitric oxide in the mustard oil-induced neurogenic inflammation of the rat paw skin.
Eur J Pharmacol. 1993; 232(1):113-120
Doi: 10.1016/0014-2999(93)90735-Z
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** Lippe, IT; Stabentheiner, A; Holzer, P
Role of nitric oxide in the vasodilator but not exudative component of mustard oil-induced inflammation in rat skin.
Agents Actions. 1993; 38 Spec No(1): C22-C24.
Doi: 10.1007/BF01991125
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** Holzer, P; Lippe, IT
Gastric mucosal hyperemia due to acid backdiffusion depends on splanchnic nerve activity.
Am J Physiol. 1992; 262(3 Pt 1):G505-G509
Doi: 10.1152/ajpgi.1992.262.3.G505
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** Holzer, P; Lippe, IT; Amann, R
Participation of capsaicin-sensitive afferent neurons in gastric motor inhibition caused by laparotomy and intraperitoneal acid.
Neuroscience. 1992; 48(3):715-722
Doi: 10.1016%2F0306-4522%2892%2990414-W
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** Lippe, IT; Holzer, P
Participation of endothelium-derived nitric oxide but not prostacyclin in the gastric mucosal hyperaemia due to acid back-diffusion.
Br J Pharmacol. 1992; 105(3):708-714
Doi: 10.1111/j.1476-5381.1992.tb09043.x
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** Holzer, P; Lippe, IT
Role of calcitonin gene-related peptide in gastrointestinal blood flow.
Ann N Y Acad Sci. 1992; 657(1):228-239
Doi: 10.1111/j.1749-6632.1992.tb22771.x
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** Casini, A; Lippe, IT; Evangelista, S; Geppetti, P; Santicioli, P; Urso, C; Maggi, CA; Surrenti, C
Sensory denervation with capsaicin reduces the liver collagen deposition induced by common bile duct obstruction in rats.
Adv Exp Med Biol. 1991; 298(3): 285-293.
Doi: 10.1007/978-1-4899-0744-8_25
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** Lippe, IT
Effect of calcitonin gene-related peptide (CGRP) on aspirin- and ethanol-induced injury in the rat stomach.
Adv Exp Med Biol. 1991; 298(3): 167-174.
Doi: 10.1007/978-1-4899-0744-8_15
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** Holzer, P; Lippe, II; Raybould, HE; Pabst, MA; Livingston, EH; Amann, R; Peskar, BM; Peskar, BA; Taché, Y; Guth, PH
Role of peptidergic sensory neurons in gastric mucosal blood flow and protection.
Ann N Y Acad Sci. 1991; 632(3):272-282
Doi: 10.1111/j.1749-6632.1991.tb33115.x
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** Butkow, N; Wheatley, AM; Lippe, IT; Marcus, RH; Rosendorff, C
The role of calcium in the enhanced myocardial contractility of the hyperthyroid rat heart.
Basic Res Cardiol. 1990; 85(3):297-306
Doi: 10.1007/BF01907118
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** Casini, A; Lippe, IT; Evangelista, S; Geppetti, P; Santicioli, P; Urso, C; Paglierani, M; Maggi, CA; Surrenti, C
Effect of sensory denervation with capsaicin on liver fibrosis induced by common bile duct ligation in rat.
J Hepatol. 1990; 11(3):302-312
Doi: 10.1016/0168-8278(90)90212-A
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** Evangelista, S; Renzi, D; Lippe, IT; Mantellini, P; Guzzi, P; Maggi, CA
Intraluminal release of PGE2 due to gastric perfusion of urethane-anaesthetized rats with hydrochloric or taurocholic acid.
INT J TISSUE REACT. 1990; 12(4): 237-241.
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** Geppetti, P; Del Bianco, E; Santicioli, P; Lippe, IT; Maggi, CA; Sicuteri, F
Release of sensory neuropeptides from dural venous sinuses of guinea pig.
Brain Res. 1990; 510(1):58-62
Doi: 10.1016/0006-8993(90)90727-S
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** Giuliani, S; Lippe, IT; Maggi, CA; Meli, A
Dual effects of cholecystokinin-octapeptide on duodenal motility of urethane-anesthetized rats.
J Pharmacol Exp Ther. 1990; 252(3):1312-1317
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** Holzer, P; Pabst, MA; Lippe, IT; Peskar, BM; Peskar, BA; Livingston, EH; Guth, PH
Afferent nerve-mediated protection against deep mucosal damage in the rat stomach.
Gastroenterology. 1990; 98(4):838-848
Doi: 10.1016/0016-5085(90)90005-L
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** Evangelista, S; Lippe, IT; Rovero, P; Maggi, CA; Meli, A
Tachykinins protect against ethanol-induced gastric lesions in rats.
Peptides. 1989; 10(1):79-81
Doi: 10.1016/0196-9781(89)90080-6
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** Geppetti, P; Baldi, E; Castellucci, A; Del Bianco, E; Santicioli, P; Maggi, CA; Lippe, IT; Amann, R; Skofitsch, G; Theodorsson, E
Calcitonin gene-related peptide in the rat kidney: occurrence, sensitivity to capsaicin, and stimulation of adenylate cyclase.
Neuroscience. 1989; 30(2):503-513
Doi: 10.1016/0306-4522(89)90268-6
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** Holzer, P; Lippe, IT
Protein kinase C may regulate the tonic component of intestinal smooth muscle contraction in response to substance P.
Naunyn Schmiedebergs Arch Pharmacol. 1989; 339(1-2):214-220
Doi: 10.1007/BF00165146
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** Holzer, P; Pabst, MA; Lippe, IT
Intragastric capsaicin protects against aspirin-induced lesion formation and bleeding in the rat gastric mucosa.
GASTROENTEROLOGY. 1989; 96(6): 1425-1433.
Doi: 10.1016/0016-5085(89)90508-8
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** Lippe, IT; Holzer, P
The diacylglycerol kinase inhibitor, R 59022, suppresses contractility of intestinal smooth muscle.
Eur J Pharmacol. 1989; 159(1):1-8
Doi: 10.1016/0014-2999(89)90037-X
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** Lippe, IT; Lorbach, M; Holzer, P
Close arterial infusion of calcitonin gene-related peptide into the rat stomach inhibits aspirin- and ethanol-induced hemorrhagic damage.
Regul Pept. 1989; 26(1):35-46
Doi: 10.1016/0167-0115(89)90102-X
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** Lippe, IT; Pabst, MA; Holzer, P
Intragastric capsaicin enhances rat gastric acid elimination and mucosal blood flow by afferent nerve stimulation.
Br J Pharmacol. 1989; 96(1):91-100
Doi: 10.1111/j.1476-5381.1989.tb11788.x
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Toxicol Pathol. 1989; 17(2):317-329
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The effect of omega conotoxin GVIA, a peptide modulator of the N-type voltage sensitive calcium channels, on motor responses produced by activation of efferent and sensory nerves in mammalian smooth muscle.
Naunyn Schmiedebergs Arch Pharmacol. 1988; 338(2):107-113
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Basic Res Cardiol. 1988; 83(6):634-646
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Br J Pharmacol. 1987; 90(4):753-761
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Acta Physiol Hung. 1987; 69(3-4):403-411
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Peptides. 1986; 7(5):761-765
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Regul Pept. 1986; 16(3-4):305-314
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** Holzer, P; Lippe, IT
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Eur J Pharmacol. 1985; 117(3):329-335
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Br J Pharmacol. 1984; 82(1):259-267
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D-Met2, Pro5enkephalinamide and dynorphin-(1-13) inhibit the cholinergic contraction induced in the guinea-pig ileum by substance P.
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