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Brezinsek Hans-Peter |

** = Publications listed in SCI/SSCI/Pubmed

2024

Full paper/article (Journal)

** Moazedi-Fuerst, FC; Lackner, A; Kreuzer, SM; Eller, K; Odler, B; Kovacs, G; Flick, H; Talakic, E; Hermann, J; Venhoff, N; Venhoff, A; Hafner, F; Brodmann, M; Jud, P; Yazdani-Biuki, B; Husic, R; Salmhofer, W; Stradner, MH; Graninger, WB; Thiel, J; Brezinschek, HP Successful long-term systemic sclerosis treatment by high-frequent low-dose B cell-depleting therapy.
J Autoimmun. 2024; 147: 103246 Doi: 10.1016/j.jaut.2024.103246
Web of Science PubMed FullText FullText_MUG

 

Abstract (Journal)

** Stradner, M; Monedeiro, F; Zuegner, E; Prietl, B; Oberhuber, M; Khalil, M; Magnes, C; Brezinsek, HP; Libiseller, A; Pieber, T Comparative Immuno-Metabolomics Shows Singular Changes in Systemic Lupus Erythematosus Metabolic Phenotype Induced by T-Cell Activation
ARTHRITIS RHEUMATOL. 2024; 76: 3647-3648.-ACR Convergence 2024; NOV 15-19, 2024; Washington, USA.
Web of Science

 

2022

Short report/Letter

** Karonitsch, T; Yeghiazaryan, L; Lackner, A; Brezinsek, HP; Stamm, TA; Konig, F; Aletaha, D; Smolen, JS Targeting type I interferon (IFN) signalling in patients with RA with a high type I IFN gene signature
RMD OPEN. 2022; 8(2): e002525 Doi: 10.1136/rmdopen-2022-002525 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Abstract (Journal)

** D'orazio, M; Daher, M; Lackner, A; Kielhauser, S; Zenz, S; Gretler, J; Thiel, J; Brezinsek, HP; Furst-Moazedi, F ABATACEPT AS THERAPY OPTION IN SYSTEMIC SCLEROSIS (SSC) PATIENTS AFTER YEARS OF GRAZER- PROTOCOL TREATMENT- OUR EXPERIENCE
ANN RHEUM DIS. 2022; 81: 1493-1493.-EULAR; JUN 1-4, 2022; Copenhagen, Denmark. Doi: 10.1136/annrheumdis-2022-eular.4711 [Poster]
Web of Science FullText FullText_MUG

 

** D'orazio, M; Lackner, A; Zenz, S; Haidmayer, A; Gretler, J; Kielhauser, S; Brezinsek, HP; Moazedi-Fürst F Transthoracic lung sonography (LUS) – useful surveillance tool in systemic sclerosis associated interstitial lung disease.
Annals of Rheumatic Diseases. 2022; 81(S1):758-759.-EULAR 2022 – Annual European Congress of Rheumatology; JUN 1-4, 2022; Kopenhagen, DANMARK. Doi: 10.1136/annrheumdis-2022-eular.4430 [Poster]
Web of Science FullText FullText_MUG

 

Abstract (Proceedings)

** Dreo, B; Prietl, B; Kofler, S; Pfeifer, S; Sourij, H; Moazedi-Fürst, F; Kreuzer, S; D'Orazia, M; Zenz, S; Thiel, J; Stradner, MH; Brezinsek, HP Rituximab does not alter expression of co-stimulation marker CD19 on B cells in Systemic Sclerosis patients
Supplementay Issue of Annals of Rheumatic Diseases. 2022; 81(1):1144-1145.-EULAR 2022 - Annual European Congress of Rheumatology; JUN 1-4 2022; Copenhagen. Doi: 10.1136/annrheumdis-2022-eular.768
Web of Science FullText FullText_MUG

 

2021

Short report/Letter

** Gressenberger, P; Jud, P; Kovacs, G; Kreuzer, S; Brezinsek, HP; Guetl, K; Muster, V; Kolesnik, E; Schmidt, A; Odler, B; Adelsmayr, G; Neumeister, P; Brcic, L; Zenz, S; Weber, K; Gary, T; Brodmann, M; Graninger, WB; Moazedi-Fürst, FC Rituximab as a Treatment Option after Autologous Hematopoietic Stem Cell Transplantation in a Patient with Systemic Sclerosis.
J Pers Med. 2021; 11(7): Doi: 10.3390/jpm11070600 (- Case Report) [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2020

Abstract (Journal)

** Dreo, B; Prietl, B; Kofler, S; Sourij, H; Lackner, A; Moazedi-Furst, F; D'orazio, M; Stradner, M; Graninger, W; Brezinschek, HP ABATACEPT ALTERS THE FREQUENCY OF IMMUNOREGULATORY AND EFFECTOR T CELL SUBPOPULATIONS IN RHEUMATOID ARTHRITIS.
ANN RHEUM DIS. 2020; 79: 225-225.-Annual European Congress of Rheumatology (EULAR); JUN 03, 2020; ELECTR NETWORK. Doi: 10.1136/annrheumdis-2020-eular.4894 [Onlinepräsentation]
Web of Science FullText FullText_MUG

 

** Zenz, S; Dreo, B; Prietl, B; Kofler, S; Sourij, H; Lackner, A; D'orazio, M; Brickmann, K; Gretler, J; Furst-Moazedi, F; Stradner, M; Graninger, W; Brezinsek, HP DRUG DEPENDENT ALTERATIONS IN B-CELL REPERTOIRE IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS WITH LOW DISEASE ACTIVITY.
ANN RHEUM DIS. 2020; 79: 1369-1369.-Annual European Congress of Rheumatology (EULAR); JUN 03, 2020; ELECTR NETWORK. Doi: 10.1136/annrheumdis-2020-eular.4412 [Poster]
Web of Science FullText FullText_MUG

 

2019

Abstract (Journal)

** Dreo, B; Prietl, B; Kofler, S; Sourij, H; Lackner, A; Furst-Moazedi, F; D'Orazio, M; Stradner, M; Graninger, W; Brezinsek, HP RITUXIMAB SIGNIFICANTLY DIMINISHES CD86+B CELLS IN SYSTEMIC SCLEROSIS
ANN RHEUM DIS. 2019; 78: 1212-1213.-Annual European Congress of Rheumatology (EULAR); JUN 12-15, 2019; Madrid, SPAIN. Doi: 10.1136/annrheumdis-2019-eular.8047 [Poster] [OPEN ACCESS]
Web of Science FullText FullText_MUG

 

** Dreo, B; Prietl, B; Kofler, S; Sourij, H; Lackner, A; Moazedi-Fuerst, F; D'Orazio, M; Stradner, M; Graninger, W; Brezinschek, HP Negative Immune Checkpoint Molecules on T Regulator Cells Distinguish RA, SLE and Healthy Controls
ARTHRITIS RHEUMATOL. Arthritis Rheumatol. 2019. 2019; 71(S 10):-2019 ACR/ARP Annual Meeting; NOV 8-13, 2019; Atlanta, USA. [Poster]
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** Zenz, S; Dreo, B; Lackner, A; Prietl, B; Kofler, S; Sourij, H; Moazedi-Fuerst, F; D'Orazio, M; Stradner, M; Graninger, W; Brezinschek, HP Diminished Memory B-cells in Systemic Lupus Erythematosus Patients with Low Disease Activity
ARTHRITIS RHEUMATOL. Arthritis Rheumatol. 2019; 71(S 10):-2019 ACR/ARP Annual Meeting; NOV 8-13, 2019; Atlanta, USA. [Poster]
Web of Science

 

2018

Abstract (Journal)

** D'Orazio, M; Fliesser, E; Moazedi-Furst, F; Stradner, M; Kielhauser, S; Fessler, J; Brezinschek, HP Characterization of CD20+T Cells in Patients with Systemic Sclerosis
ARTHRITIS RHEUMATOL. 2018; 70: -Annual Congress of the American College of Rheumatology; OKT 20-24, 2018; Chicago, USA. [Poster]
Web of Science

 

** Valentin, T; Stelzl, E; Kessler, HH; Krause, R; Zollner-Schwetz, I; Prattes, J; Wunsch, S; Fruhwald, F; Brezinschek, HP; Flick, H Detection of Pneumocystis jiroveci DNA in HIV-uninfected patients: a single center experience
WIEN KLIN WOCHENSCHR. 2018; 130: 265-265. [Poster]
Web of Science FullText

 

2017

Full paper/article (Journal)

** Fabian, E; Schneeweiss, B; Valentin, T; Flick, H; Aigelsreiter, A; Hofmann-Wellenhof, R; Cerroni, L; Goritschan, AM; Brezinsek, HP; Zitta, S; Rosenkranz, A; Graninger, W; Krejs, GJ Clinical-Pathological Conference Series from the Medical University of Graz : Case No 162: A 30-year-old woman from Nigeria with fever 3 months postpartum.
Wien Klin Wochenschr. 2017; 129(3-4):145-152 Doi: 10.1007/s00508-016-1164-9 (- Case Report) [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Abstract (Journal)

** Brezinschek, HP; Kielhauser, S; Graninger, W; Moazedi-Furst, F Safety and Efficacy of Long-Time Intensified Rituximab Treatment in Patients with Systemic Sclerosis
ARTHRITIS RHEUMATOL. 2017; 69: -ACR; Washington, USA. [Oral Communication]
Web of Science

 

** Prietl, B; Kofler, S; Stanzer, S; Brezinsek, H; Munzker, J; Pieber, T; Sourij, H Response to IL-2 signalling is specifically impaired in type 1 diabetes
DIABETOLOGIA. 2017; 60: S204-S204.-53rd Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD); SEP 11-15, 2017; Lisbon, PORTUGAL. [Poster]
Web of Science

 

2016

Full paper/article (Journal)

** Stradner, MH; Dejaco, C; Brickmann, K; Graninger, WB; Brezinschek, HP A combination of cellular biomarkers predicts failure to respond to rituximab in rheumatoid arthritis: a 24-week observational study.
Arthritis Res Ther. 2016; 18(9):190-190 Doi: 10.1186/s13075-016-1091-1 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Review

** Leeb, BF; Brezinschek, HP; Rintelen, B RADAI-5 and electronic monitoring tools.
Clin Exp Rheumatol. 2016; 34(5 Suppl 101):S5-S10 [OPEN ACCESS]
Web of Science PubMed

 

2015

Full paper/article (Journal)

** Leeb, BF; Haindl, PM; Brezinschek, HP; Mai, HT; Deutsch, C; Rintelen, B Patient-centered psoriatic arthritis (PsA) activity assessment by Stockerau Activity Score for Psoriatic Arthritis (SASPA).
BMC Musculoskelet Disord. 2015; 16(1):73-73 Doi: 10.1186/s12891-015-0512-7 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Puchner, R; Brezinschek, HP; Fritz, J; Herold, M; Mustak, M; Nothnagl, T; Puchner, SE; Studnicka-Benke, A; Leeb, BF Is the state of health of rheumatoid arthritis patients receiving adequate treatment, predictable? - Results of a survey.
BMC Musculoskelet Disord. 2015; 16(1):109-109 Doi: 10.1186/s12891-015-0567-5 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Richtig, E; Trapp, EM; Avian, A; Brezinsek, HP; Trapp, M; Egger, JW; Kapfhammer, HP; Rohrer, PM; Berghold, A; Curiel-Lewandrowski, C; Demel, U Psychological Stress and Immunological Modulations in Early-stage Melanoma Patients.
Acta Derm Venereol. 2015; 95(6):691-695 Doi: 10.2340/00015555-2045 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Abstract (Journal)

** Brezinschek, HP; Fürst-Moazedi, F; Kielhauser, S; Stradner, M; Graninger, WB Rituximab-Non-Responders Fail to Down Regulate CD19 on Naive B cells
Arthritis Rheum. 2015; 67(S10):-ACR/ARHP Annual Meeting; NOV 6-11, 2015; San Francisco, USA. [Poster]
Web of Science

 

2014

Full paper/article (Journal)

** Leeb, BF; Haindl, PM; Brezinschek, HP; Nothnagl, T; Rintelen, B RADAI-5 to monitor rheumatoid arthritis.
Clin Exp Rheumatol. 2014; 32(5 Suppl 85):S-55-S-58
Web of Science PubMed

 

** Pichler, K; Fischerauer, S; Ferlic, P; Martinelli, E; Brezinsek, HP; Uggowitzer, PJ; Loffler, JF; Weinberg, AM; Immunological Response to Biodegradable Magnesium Implants.
JOM. 2014; 66(4): 573-579. Doi: 10.1007/s11837-014-0874-6
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** Puchner, R; Brezinschek, HP; Herold, M; Nothnagl, T; Studnicka-Benke, A; Fritz, J; Leeb, BF Quality of care of rural rheumatoid arthritis patients in Austria.
Wien Klin Wochenschr. 2014; 126(11-12):360-367 Doi: 10.1007/s00508-014-0540-6
Web of Science PubMed FullText FullText_MUG

 

Short report/Letter

** Moazedi-Fuerst, FC; Kielhauser, SM; Brickmann, K; Hermann, J; Lutfi, A; Meilinger, M; Brezinschek, HP; Graninger, WB Rituximab for systemic sclerosis: arrest of pulmonary disease progression in five cases. Results of a lower dosage and shorter interval regimen.
Scand J Rheumatol. 2014; 43(3):257-258 Doi: 10.3109/03009742.2013.869617 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Abstract (Journal)

** Stelzer, I; Brezinschek, HP; Fuchs, R; Mangge, H; Graninger,W; Demel, U Intravenous Immunogloglobulin Therapy Affects The Number And The Function Of Immune Cells In Common Variable Immunodeficiency
J Clin Immunol. 2014; 34(Suppl.):S305-S305.-16th Biennial Meeting of the European Society For Immunodeficiencies; OCT 29 - NOV 1, 2014; Prague, CZECH REPUBLIK. [Poster]
Web of Science

 

2013

Full paper/article (Journal)

** Rintelen, B; Sautner, J; Haindl, P; Mai, H; Brezinschek, HP; Leeb, BF Remission in rheumatoid arthritis: a comparison of the 2 newly proposed ACR/EULAR remission criteria with the rheumatoid arthritis disease activity index-5, a patient self-report disease activity index.
J Rheumatol. 2013; 40(4):394-400 Doi: 10.3899/jrheum.120952
Web of Science PubMed FullText FullText_MUG

 

Abstract (Journal)

** Puchner, R; Brezinschek, H; Herold, M; Nothnagl, T; Leeb, B Quality of care of rural, rheumatoid arthritis patients in Austria
Z RHEUMATOL. 2013; 72: 55-55. [Oral Communication]
Web of Science

 

2012

Full paper/article (Journal)

** Brezinschek, HP; Rainer, F; Brickmann, K; Graninger, WB B lymphocyte-typing for prediction of clinical response to rituximab.
Arthritis Res Ther. 2012; 14(4):R161-R161 Doi: 10.1186/ar3901 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Abstract (Journal)

** Brickmann, K; Furst, F; Kielhauser, S; Hermann, J; Brezinsek, HP; Graninger, W RITUXIMAB IN SEVERE SYSTEMIC SCLEROSIS: AN EXPERIENCE
RHEUMATOLOGY. 2012; 51: I19-I19.-Conference on Excellence in Rheumatology; JAN 25-28, 2012; Madrid, SPAIN. [Poster]
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2011

Full paper/article (Journal)

** Brickmann, K; Brezinschek, RI; Yazdani-Biuki, B; Graninger, WB; Brezinschek, HP Superior specificity of anti-citrullinated peptide antibodies in patients with chronic lymphocytic leukemia and arthritis.
Clin Exp Rheumatol. 2011; 28(6):888-891
Web of Science PubMed

 

Abstract (Journal)

** Brezinschek, HP; Rainer, F; Brickmann, K; Lunzer, R; Graninger, WB Clinical Response and B Cell Analysis by High-Sensitive Flowcytometry after the Second Course of Rituximab
ARTHRITIS RHEUM. 2011; 63(10):S497-S497.-ACR Annual Scientific Meeting; NOV 4-9, 2011; Chicago, USA. [Poster]
Web of Science

 

** Kielhauser, SM; Fuerst, FC; Brickmann, K; Hermann, J; Brezinschek, HP; Graninger WB Rituximab in severe systemic sclerosis- an experience
Wiener Klinsche Wochenschrift. 2011; 123(17):A68-A68.-ÖGIM ; Oct 5- 7,2011; Innsbruck,Austria. [Poster]
Web of Science

 

** Kielhauser, SM; Fuerst, FC; Brickmann, K; Tripolt, NJ; Zechner, PM; Scheidl, S; Lutfi, A; Gretler, J; Graninger, WB Pulmonary echography in systemic sclerosis
Wiener klinsche Wochenschrift. 2011; 123(17):A69-A69.-ÖGIM; Oct ,5-7 2011; Inssbruck,Austria. [Poster]
Web of Science

 

2010

Full paper/article (Journal)

** Leeb, BF; Böttcher, E; Brezinschek, HP; Czerwenka, C; Herold, M; Hitzelhammer, H; Mayrhofer, F; Puchner, R; Rainer, F; Rintelen, B; Schirmer, M; Stuby, U; Bröll, H The use of tumour necrosis factor alpha-blockers in daily routine. An Austrian consensus project.
Clin Rheumatol. 2010; 29(2): 167-174. Doi: 10.1007/s10067-009-1304-y [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Yazdani-Biuki, B; Krippl, P; Brickmann, K; Fuerst, F; Langsenlehner, U; Paulweber, B; Pilger, E; Wascher, TC; Brezinschek, HP; Renner, W The functional promoter polymorphism of the coagulation factor XII gene is not associated with peripheral arterial disease.
Angiology. 2010; 61(2):211-215 Doi: 10.1177/0003319709337305
Web of Science PubMed FullText FullText_MUG

 

2009

Full paper/article (Journal)

** Fleischmann, R; Vencovsky, J; van Vollenhoven, R; Borenstein, D; Box, J; Coteur, G; Goel, N; Brezinschek, HP; Innes, A; Strand, V Efficacy and safety of certolizumab pegol monotherapy every 4 weeks in patients with rheumatoid arthritis failing previous disease-modifying antirheumatic therapy: the FAST4WARD study.
Ann Rheum Dis. 2009; 68(6): 805-811. Doi: 10.1136/ard.2008.099291 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2008

Full paper/article (Journal)

** Brezinschek, HP Mechanisms of muscle pain : Significance of trigger points and tender points.
Z Rheumatol. 2008; 67(8): 653-657. Doi: 10.1007/s00393-008-0353-y
Web of Science PubMed FullText FullText_MUG

 

** Machold, KP; Brezinsek, HP; Leeb, BF; Pflugbeil, S; Rainer, F; Singer, F; Skoumal, M; Stamm, TA; Herold, M Austrian expert opinion on the standard for expert assessment of course of illness in patients with chronic polyarthritis (rheumatoid arthritis)].
Wien Klin Wochenschr. 2008; 120(7-8):234-241 Doi: 10.1007/s00508-008-0958-9
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Short report/Letter

** Yazdani-Biuki, B; Brickmann, K; Langsenlehner, U; Renner, W; Truschnig, M; Krippl, P; Fürst, F; Graninger, WB; Brezinschek, HP The Glu228Ala polymorphism in the ligand-binding domain of death receptor 4 is not associated with rheumatoid arthritis.
Ann Rheum Dis. 2008; 67(7): 1053-1054. Doi: 10.1136/ard.2007.086124 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG Google Scholar

 

Review

** Brezinschek, HP; Hofstaetter, T; Leeb, BF; Haindl, P; Graninger, WB Immunization of patients with rheumatoid arthritis with antitumor necrosis factor alpha therapy and methotrexate.
Curr Opin Rheumatol. 2008; 20(3):295-299 Doi: 10.1097/BOR.0b013e3282ffdeca
Web of Science PubMed FullText FullText_MUG Google Scholar

 

Abstract (Journal)

** Deutsch, AJA; Brezinschek, RI; Brezinschek, HP; Beham-Schmid, C; Neumeister, P Relapsed MALT Lymphomas Are Associated with a Restricted VH3-30.3 Immunoglobulin VH Gene Repertoire and Are Targeted by Aberrant Somatic Hypermutation.
BLOOD. 2008; 112(11):978-978.-50th Annual Meeting of the American- Society-of-Hematology; DEC 06-09, 2008; San Francisco, CA. [Poster]
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2007

Abstract (Journal)

** Brickmann, K; Yazdani-Biuki, BJ; Eibinger, C; Graninger, WB; Brezinschek, HR Determination of rheumatoid factors (RF) and anti cyclic citruillinated peptide antibodies (anti-CCP) in synovial fluid provides no additional information
ANN RHEUM DIS. 2007; 66: 561-561.-EULAR Annual Scientific Meeting; JUN 13-16, 2007; Barcelona, SPAIN. [Poster]
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** Brickmann, KS; Yazdani-Biuki, BJ; Brezinschek, RI; Graninger, WB; Brezinschek, HP Sequential etanercept and rituximab therapy in patients with active RA-SERRA
ARTHRITIS RHEUM. 2007; 56(12):4278-4278.-ACR Annual Scientific Meeting; NOV 6-11, 2007; Boston, USA. [Poster]
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2006

Full paper/article (Journal)

** Martinez-Gamboa, L; Brezinschek, HP; Burmester, GR; Dörner, T Immunopathologic role of B lymphocytes in rheumatoid arthritis: rationale of B cell-directed therapy.
AUTOIMMUN REV. 2006; 5(7): 437-442. Doi: 10.1016/j.autrev.2006.02.004
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** Yazdani-Biuki, B; Brickmann, K; Wohlfahrt, K; Mueller, T; März, W; Renner, W; Gutjahr, M; Langsenlehner, U; Krippl, P; Wascher, TC; Paulweber, B; Graninger, W; Brezinschek, HP The MHC2TA -168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients.
Arthritis Res Ther. 2006; 8(4):R97-R97 Doi: 10.1186/ar1974 [OPEN ACCESS]
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** Yazdani-Biuki, B; Mueller, T; Brezinschek, HP; Hermann, J; Graninger, W; Wascher, TC Relapse of diabetes after interruption of chronic administration of anti-tumor necrosis factor-alpha antibody infliximab: a case observation.
Diabetes Care. 2006; 29(7): 1712-1713. Doi: 10.2337/dc06-0636 (- Case Report) [OPEN ACCESS]
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Review

** Brezinschek, HP; Brickmann, K; Yazdani-Biuki, B; Dörner, T; Graninger, WB; Brezinschek, RI Treatment of rheumatoid arthritis in the 21st century: targeting B-lymphocytes.
Wien Med Wochenschr. 2006; 156(1-2): 61-67. Doi: 10.1007/s10354-005-0241-x
PubMed FullText FullText_MUG Google Scholar

 

Abstract (Journal)

** Brickmann, KP; Yazdani-Biuki, BJ; Graninger, M; Brezinschek, RI; Stoiser, E; Graninger, WB; Brezinschek, HP Autoantibodies against mutated citrullinated Vimentin (anti-MCV) in the elderly population
ANN RHEUM DIS. 2006; 65: 580-581.-Annual European Congress of Rheumatology (EULAR 2006); JUN 21-24, 2006; Amsterdam, NETHERLANDS.
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** Yazdani-Biuki, BJ; Brickmann, K; Brezinschek, RI; Muller, T; Graninger, W; Brezinschek, H The positive predictive value of anti-cyclic citrullinated peptide antibodies for rheumatoid arthritis compared with psoriatic arthritis and chronic lymphocytic B-cell leukemia
ANN RHEUM DIS. 2006; 65: 159-159.-Annual European Congress of Rheumatology (EULAR 2006); JUN 21-24, 2006; Amsterdam, NETHERLANDS.
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2005

Full paper/article (Journal)

** Monson, NL; Brezinschek, HP; Brezinschek, RI; Mobley, A; Vaughan, GK; Frohman, EM; Racke, MK; Lipsky, PE Receptor revision and atypical mutational characteristics in clonally expanded B cells from the cerebrospinal fluid of recently diagnosed multiple sclerosis patients.
J NEUROIMMUNOL. 2005; 158(1-2): 170-181. Doi: 10.1016/j.jneuroim.2004.04.022
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** Yazdani-Biuki, B; Stadlmaier, E; Mulabecirovic, A; Brezinschek, R; Tilz, G; Demel, U; Mueller, T; Brickmann, K; Graninger, WB; Brezinschek, HP Blockade of tumour necrosis factor {alpha} significantly alters the serum level of IgG- and IgA-rheumatoid factor in patients with rheumatoid arthritis.
Ann Rheum Dis. 2005; 64(8):1224-1226 Doi: 10.1136/ard.2004.030262 [OPEN ACCESS]
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Abstract (Journal)

** Brickmann, KS; Yazdani-Biuki, BJ; Brezinschek, RI; Mulabecirovic, A; Graninger, WB; Dorner, T; Brezinschek, H Different reading frame usage of variable heavy chain diversity segments in patients with systemic lupus erythematosus and rheumatoid arthritis
ANN RHEUM DIS 2005 64: 229-229. [Poster]
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** Yazdani-Biuki, BJ; Mueller, T; Brezinschek, H; Graninger, WB; Pilger, E; Brodmann, M Seasonal variation in acute phase proteins in patients with primary Raynaud's phenomenon
ANN RHEUM DIS 2005 64: 300-300. [Poster]
Web of Science

 

2004

Short report/Letter

** Yazdani-Biuki, B; Stelzl, H; Brezinschek, HP; Hermann, J; Mueller, T; Krippl, P; Graninger, W; Wascher, TC Improvement of insulin sensitivity in insulin resistant subjects during prolonged treatment with the anti-TNF-alpha antibody infliximab.
EUR J CLIN INVEST. 2004; 34(9): 641-642. Doi: 10.1111/j.1365-2362.2004.01390.x (- Case Report)
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Abstract (Journal)

** Yazdani-Biuki, B; Wohlfahrt, K; Mueller, T; Mulabecirovic, A; Brezinschek, RI; Graninger, WB; Brezinschek, HP A modified disease activity score with fibrinogen as a tool for the assesment of disease activity in patients with rheumatoid arthritis
ARTHRITIS RHEUM 2004 50: S164-S164.
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** Yazdani-Biuki, BJ; Mulabecirovic, A; Mueller, T; Hermann, J; Graninger, WB; Brezinschek, H Significant increase of IGG- and IGA-rheumatoid factor in patients with rheumatoid arthritis during prolonged treatment with etanercept
ANN RHEUM DIS 2004 63: 140-140. [Poster]
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Comment

** Yazdani-Biuki, B; Wohlfahrt, K; Mulabecirovic, A; Mueller, T; Hermann, J; Graninger, WB; Brezinschek, HP; Brezinschek, RI Long term treatment of psoriatic arthritis with infliximab.
ANN RHEUM DIS. 2004; 63(11): 1531-1532. [OPEN ACCESS]
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2003

Abstract (Journal)

** Mulabecirovic, A; Yazdani-Biuki, B; Brezinschek, R; Muller, T; Hermann, J; Brezinschek, HP Superantigen seems to shape the naive synovial tissue B cell repertoire in rheumatoid arthritis
ANN RHEUM DIS 2003 62: 141-141.
Web of Science

 

** Muller, T; Liebscher, B; Yazdani-Biuki, B; Eder, S; Gretler, J; Brezinschek, H; Hermann, J Efficacy and safety of leflunomide in rheumatoid arthritis patients treated in an outpatient clinic
ANN RHEUM DIS 2003 62: 423-423.
Web of Science

 

** Yazdani-Biuki, B; Bahadori, B; Mulabecirovic, A; Brezinschek, R; Brezinschek, HP Isoprostane as a marker of disease activity in SLE patients.
ARTHRITIS RHEUM 2003 48: 1488-1488.
Web of Science

 

** Yazdani-Biuki, B; Brezinschek, RJ; Gretler, J; Eder, S; Mueller, T; Hermann, J; Mulabecirovic, A; Krappinger, A; Stadlmaier, E; Uitz, E; Brezinschek, HP Comparison of antibody titers with sledai, modified SLEDAI and ECLAM in SLE patients
ANN RHEUM DIS 2003 62: 435-435.
Web of Science

 

2001

Full paper/article (Journal)

** Monson, NL; Foster, SJ; Brezinschek, HP; Brezinschek, RI; Dörner, T; Lipsky, PE The role of CD40-CD40 ligand (CD154) interactions in immunoglobulin light chain repertoire generation and somatic mutation.
Clin Immunol. 2001; 100(1):71-81 Doi: 10.1006/clim.2001.5049
Web of Science PubMed FullText FullText_MUG

 

Abstract (Journal)

** Yazdani-Biuki, B; Brezinschek, R; Dorner, T; Jakobi, AM; Hermann, J; Muller, T; Eder, S; Gretler, J; Fuchshofer, A; Brezinschek, HP Naive B cells in SLE preferentially utilize diversity gene segments in reading frames encoding hydrophobic amino acids
J RHEUMATOL. 2001; 28: 87-87.
Web of Science

 

** Yazdani-Biuki, BJ; Brezinschek, RI; Doerner, T; Jakobi, AM; Maizen, C; Brezinschek, HP Preferential utilization of D segments in hydrophobic reading frames in antibodies is a specific feature of SLE but not RA or normal B-cells.
ARTHRITIS RHEUM. 2001; 44(9): S76-S76.
Web of Science

 

2000

Full paper/article (Journal)

** Brezinschek, HP; Dörner, T; Monson, NL; Brezinschek, RI; Lipsky, PE The influence of CD40-CD154 interactions on the expressed human V(H) repertoire: analysis of V(H) genes expressed by individual B cells of a patient with X-linked hyper-IgM syndrome.
Int Immunol. 2000; 12(6):767-775 Doi: 10.1093/intimm/12.6.767 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Abstract (Journal)

** Brezinschek, HP; Brezinschek, RI; Lipsky, PE V-H-specific selection of B cells in the synovial tissue from a patient with rheumatoid arthritis.
ARTHRITIS RHEUM. 2000; 43(9): S77-S77.
Web of Science

 

** Brezinschek, HP; Brezinschek, RI; Lipsky, PE; Frohman, E B cells in the cerebrospinal fluid from a patient with multiple sclerosis are clonally expanded and highly mutated
NEUROLOGY. 2000; 54(7): A276-A277.
Web of Science

 

1998

Full paper/article (Journal)

** Brezinschek, HP; Brezinschek, RI; Dörner, T; Lipsky, PE Similar characteristics of the CDR3 of V(H)1-69/DP-10 rearrangements in normal human peripheral blood and chronic lymphocytic leukaemia B cells.
Br J Haematol. 1998; 102(2):516-521 Doi: 10.1046/j.1365-2141.1998.00787.x
Web of Science PubMed FullText FullText_MUG

 

** Brezinschek, HP; Foster, SJ; Dörner, T; Brezinschek, RI; Lipsky, PE Pairing of variable heavy and variable kappa chains in individual naive and memory B cells.
J Immunol. 1998; 160(10):4762-4767 [OPEN ACCESS]
Web of Science PubMed

 

** Dörner, T; Brezinschek, HP; Foster, SJ; Brezinschek, RI; Farner, NL; Lipsky, PE Delineation of selective influences shaping the mutated expressed human Ig heavy chain repertoire.
J Immunol. 1998; 160(6):2831-2841 [OPEN ACCESS]
Web of Science PubMed

 

** Dörner, T; Brezinschek, HP; Foster, SJ; Brezinschek, RI; Farner, NL; Lipsky, PE Comparable impact of mutational and selective influences in shaping the expressed repertoire of peripheral IgM+/CD5- and IgM+/CD5+ B cells.
Eur J Immunol. 1998; 28(2):657-668 Doi: 10.1002/(SICI)1521-4141(199802)28:02<657::AID-IMMU657>3.0.CO;2-Z
Web of Science PubMed FullText FullText_MUG

 

Review

** Dörner, T; Foster, SJ; Brezinschek, HP; Lipsky, PE Analysis of the targeting of the hypermutational machinery and the impact of subsequent selection on the distribution of nucleotide changes in human VHDJH rearrangements.
Immunol Rev. 1998; 162:161-171 Doi: 10.1111/j.1600-065X.1998.tb01439.x
Web of Science PubMed FullText FullText_MUG

 

1997

Full paper/article (Journal)

** Brezinschek, HP; Foster, SJ; Brezinschek, RI; Dörner, T; Domiati-Saad, R; Lipsky, PE Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells.
J Clin Invest. 1997; 99(10):2488-2501 Doi: 10.1172/JCI119433 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Dörner, T; Brezinschek, HP; Brezinschek, RI; Foster, SJ; Domiati-Saad, R; Lipsky, PE Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes.
J Immunol. 1997; 158(6):2779-2789 [OPEN ACCESS]
Web of Science PubMed

 

** Foster, SJ; Brezinschek, HP; Brezinschek, RI; Lipsky, PE Molecular mechanisms and selective influences that shape the kappa gene repertoire of IgM+ B cells.
J Clin Invest. 1997; 99(7):1614-1627 Doi: 10.1172/JCI119324 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Abstract (Journal)

** Brezinschek, HP; Brezinschek, RT; Foster, SJ; Dorner, T; Farner, NL; Lipsky, PE Preferential utilization of V-H genes in different B cell subsets obtained from synovial tissue.
ARTHRITIS RHEUM. 1997; 40(9): 1288-1288.
Web of Science

 

1996

Full paper/article (Journal)

** Brezinschek, RI; Brezinschek, HP; Lazarovits, AI; Lipsky, PE; Oppenheimer-Marks, N Expression of the beta 7 integrin by human endothelial cells.
Am J Pathol. 1996; 149(5):1651-1660 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText

 

** Domiati-Saad, R; Attrep, JF; Brezinschek, HP; Cherrie, AH; Karp, DR; Lipsky, PE Staphylococcal enterotoxin D functions as a human B cell superantigen by rescuing VH4-expressing B cells from apoptosis.
J Immunol. 1996; 156(10):3608-3620 [OPEN ACCESS]
Web of Science PubMed

 

** Gruschwitz, MS; Brezinschek, R; Brezinschek, HP Cytokine levels in the seminal plasma of infertile males.
J Androl. 1996; 17(2):158-163 [OPEN ACCESS]
Web of Science PubMed

 

Abstract (Journal)

** Attrep, J; Brezinschek, HP; Brezinschek, RI; Lipsky, PE Functional activity of CD40 expressed by activated T cells.
ARTHRITIS RHEUM. 1996; 39(9): 1418-1418.
Web of Science

 

** Attrep, J; Brezinschek, HP; Brezinschek, RI; Lipsky, PE Regulatory influences of CD40 on T lymphocytes.
FASEB J. 1996; 10(6): 2614-2614.
Web of Science

 

** Brezinschek, HP; Brezinschek, RI; Foster, SJ; Dorner, T; Lipsky, PE Analysis of the immunoglobulin repertoire of human B-1 (CD5+) B cells.
ARTHRITIS RHEUM. 1996; 39(9): 102-102.
Web of Science

 

** Brezinschek, RI; Brezinschek, HP; Lazarovits, AI; Lipsky, PE; OppenheimerMarks, N Human endothelial cells express the beta 7 integrin.
ARTHRITIS RHEUM. 1996; 39(9): 41-41.
Web of Science

 

** Brezinschek, RI; Brezinschek, HP; Lazarovitz, AI; Lipsky, PE; OppenheimerMarks, N Expression of the beta 7 integrin by human endothelial cells.
FASEB J. 1996; 10(6): 1177-1177.
Web of Science

 

** Dorner, T; Brezinschek, HP; Brezinschek, RI; Foster, SJ; Lipsky, PE Patterns of somatic mutations in human VH-genes.
ARTHRITIS RHEUM. 1996; 39(9): 1508-1508.
Web of Science

 

1995

Full paper/article (Journal)

** Brezinschek, HP; Brezinschek, RI; Lipsky, PE Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction.
J Immunol. 1995; 155(1):190-202
Web of Science PubMed

 

Abstract (Journal)

** ATTREP, J; BREZINSCHEK, HP; BREZINSCHEK, RI; LIPSKY, PE FUNCTION OF CD40 EXPRESSED ON HUMAN T-LYMPHOCYTES
ARTHRITIS RHEUM. 1995; 38(9): 232-232.
Web of Science

 

** BREZINSCHEK, HP; FOSTER, SJ; BREZINSCHEK, RI; LIPSKY, PE THE HUMAN-IMMUNOGLOBULIN VARIABLE HEAVY-CHAIN REPERTOIRE
ARTHRITIS RHEUM. 1995; 38(9): 1007-1007.
Web of Science

 

1994

Full paper/article (Journal)

** Wascher, TC; Hermann, J; Brezinschek, HP; Brezinschek, R; Wilders-Truschnig, M; Rainer, F; Krejs, GJ Cell-type specific response of peripheral blood lymphocytes to methotrexate in the treatment of rheumatoid arthritis.
Clin Investig. 1994; 72(7):535-540 Doi: 10.1007/BF00207484
Web of Science PubMed FullText FullText_MUG Google Scholar

 

** Wascher, TC; Hermann, J; Brezinschek, R; Brezinschek, HP; Wilders-Truschnig, M; Rainer, F; Krejs, GJ Serum levels of interleukin-6 and tumour-necrosis-factor-alpha are not correlated to disease activity in patients with rheumatoid arthritis after treatment with low-dose methotrexate.
Eur J Clin Invest. 1994; 24(1):73-75 Doi: 10.1111/j.1365-2362.1994.tb02063.x
Web of Science PubMed FullText FullText_MUG Google Scholar

 

Abstract (Journal)

** BREZINSCHEK, HP; LIPSKY, PE USAGE OF VARIABLE HEAVY-CHAIN GENES BY SINGLE HUMAN B-LYMPHOCYTES
FASEB J. 1994; 8(4): A525-A525.
Web of Science

 

** DOMIATISAAD, R; BREZINSCHEK, HP; LIPSKY, PE ACTIVATION OF HUMAN B-CELLS BY STAPHYLOCOCCAL ENTEROTOXINS - B-CELL SUPERANTIGENS
FASEB J. 1994; 8(4): A253-A253.
Web of Science

 

Note

** Silly, H; Wilderstruschnig, M; Brezinschek, R; Brezinschek, HP; Schmid, M; Kuss, I; Mucher, K; Stöger, H; Samonigg, H Varying Amounts of Tumor-Cells in the Bone-Marrow of Patients with Nonmetastatic Colorectal-Cancer
ONKOLOGIE. 1994; 17: 184-186. Doi: 10.1159/000218406
Web of Science FullText FullText_MUG

 

1993

Full paper/article (Journal)

** Brezinschek, HP; Gruschwitz, M; Sgonc, R; Moormann, S; Herold, M; Gershwin, ME; Wick, G Effects of cytokine application on glucocorticoid secretion in an animal model for systemic scleroderma.
J Autoimmun. 1993; 6(6):719-733 Doi: 10.1006/jaut.1993.1060
Web of Science PubMed FullText FullText_MUG

 

** Gruschwitz, MS; Shoenfeld, Y; Krupp, M; Gershwin, ME; Penner, E; Brezinschek, HP; Wick, G Antinuclear antibody profile in UCD line 200 chickens: a model for progressive systemic sclerosis.
Int Arch Allergy Immunol. 1993; 100(4):307-313 Doi: 10.1159/000236430
Web of Science PubMed FullText FullText_MUG

 

** Tilz, GP; Domej, W; Diez-Ruiz, A; Weiss, G; Brezinschek, R; Brezinschek, HP; Hüttl, E; Pristautz, H; Wachter, H; Fuchs, D Increased immune activation during and after physical exercise.
Immunobiology. 1993; 188(1-2):194-202 Doi: 10.1016/S0171-2985(11)80497-3
Web of Science PubMed FullText FullText_MUG

 

1992

Full paper/article (Journal)

** Herold, M; Brezinschek, HP; Gruschwitz, M; Dietrich, H; Wick, G Investigation of ACTH responses of chickens with autoimmune disease.
Gen Comp Endocrinol. 1992; 88(2):188-198 Doi: 10.1016/0016-6480(92)90250-N
Web of Science PubMed FullText FullText_MUG Google Scholar

 

** Wilders-Truschnig, MM; Leb, G; Warnkross, H; Langsteger, W; Eber, O; Dimal, P; Brezinschek, HP; Brezinschek, R; Tiran, A; Den Hartog, MT Involvement of the immune system in iodine deficient goiter.
Thyroidology. 1992; 4(1): 53-55.
PubMed Google Scholar

 

Short report/Letter

** Silly, H; Samonigg, H; Stöger, H; Brezinschek, HP; Wilders-Truschnig, M Micrometastatic tumour cells in bone marrow in colorectal cancer.
Lancet. 1992; 340(8830):1288-1288 Doi: 10.1016/0140-6736(92)92987-Q
Web of Science PubMed FullText FullText_MUG Google Scholar

 

1990

Full paper/article (Journal)

** Brezinschek, HP; Faessler, R; Klocker, H; Kroemer, G; Sgonc, R; Dietrich, H; Jakober, R; Wick, G Analysis of the immune-encodrine feedback loop in the avian system and its alteration in chickens with spontaneous autoimmune thyroiditis.
Eur J Immunol. 1990; 20(10):2155-2159 Doi: 10.1002/eji.1830201002
Web of Science PubMed FullText FullText_MUG Google Scholar

 

** Brezinschek, HP; Wilders-Truschnig, M; Leb, G; Eber, O; Dohr, G; Lanzer, G; Krejs, GJ Thyroid growth promoting serum-IgG in endemic goiter.
Acta Med Austriaca. 1990; 17 Suppl 1:26-27
Web of Science PubMed Google Scholar

 

** Wilders-Truschnig, MM; Drexhage, HA; Leb, G; Eber, O; Brezinschek, HP; Dohr, G; Lanzer, G; Krejs, GJ Chromatographically purified immunoglobulin G of endemic and sporadic goiter patients stimulates FRTL5 cell growth in a mitotic arrest assay.
J Clin Endocrinol Metab. 1990; 70(2):444-452 Doi: 10.1210/jcem-70-2-444
Web of Science PubMed FullText FullText_MUG Google Scholar

 

Review

** Wick, G; Dietrich, H; Kroemer, G; Brezinschek, HP; Faessler, R; Schuurs, AH Spontaneous autoimmune thyroiditis: new therapeutic strategies.
Immunol Ser. 1990; 52(2): 191-211.
PubMed

 

1989

Review

** Wick, G; Brezinschek, HP; Hála, K; Dietrich, H; Wolf, H; Kroemer, G The obese strain of chickens: an animal model with spontaneous autoimmune thyroiditis.
Adv Immunol. 1989; 47(2):433-500 Doi: 10.1016/S0065-2776(08)60666-5
Web of Science PubMed FullText FullText_MUG

 

1988

Full paper/article (Journal)

** Fässler, R; Dietrich, H; Krömer, G; Böck, G; Brezinschek, HP; Wick, G The role of testosterone in spontaneous autoimmune thyroiditis of Obese strain (OS) chickens.
J Autoimmun. 1988; 1(1):97-108 Doi: 10.1016/0896-8411(88)90081-9
Web of Science PubMed FullText FullText_MUG Google Scholar

 

** Fässler, R; Dietrich, H; Krömer, G; Schwarz, S; Brezinschek, HP; Wick, G Diminished glucocorticoid tonus in obese strain (OS) chickens with spontaneous autoimmune thyroiditis: increased plasma levels of a physicochemically unaltered corticosteroid-binding globulin but normal total corticosterone plasma concentration and normal glucocorticoid receptor contents in lymphoid tissues.
J Steroid Biochem. 1988; 30(1-6):375-379 Doi: 10.1016/0022-4731(88)90126-4
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** Kroemer, G; Brezinschek, HP; Faessler, R; Schauenstein, K; Wick, G Physiology and pathology of an immunoendocrine feedback loop.
Immunol Today. 1988; 9(6):163-165 Doi: 10.1016/0167-5699(88)91289-3
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** Kroemer, G; Faessler, R; Hála, K; Boeck, G; Schauenstein, K; Brezinschek, HP; Neu, N; Dietrich, H; Jakober, R; Wick, G Genetic analysis of extrathyroidal features of Obese strain (OS) chickens with spontaneous autoimmune thyroiditis.
Eur J Immunol. 1988; 18(10):1499-1505 Doi: 10.1002/eji.1830181005
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Abstract (Journal)

** BREZINSCHEK, HP; KROMER, G; FASSLER, R; JAKOBER, R; GAGGL, I; SCHAUENSTEIN, K; WICK, G DISRUPTION OF IMMUNOENDOCRINE COMMUNICATION IN SPONTANEOUS AUTOIMMUNE-THYROIDITIS
WIEN KLIN WOCHENSCHR. 1988; 100(3): 88-88.
Web of Science

 

** WICK, G; KROMER, G; BREZINSCHEK, H; FASSLER, R; DIETRICH, H; ZIEMIECKI, A A NEW ENDOGENOUS VIRUS (EV-22) OCCURRING IN OBESE STRAIN (OS) CHICKENS WITH SPONTANEOUS AUTOIMMUNE-THYROIDITIS (SAT)
FASEB J. 1988; 2(6): A1676-A1676.
Web of Science

 

1986

Abstract (Journal)

** DOHR, G; BREZINSCHEK, HP; WEIZSACKER, HW LOCALIZATION OF ELASTIC VESSELS
ANAT ANZEIGER. 1986; 161(2): 128-129.
Web of Science

 

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