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Madl Tobias |

** = Publikationen gelistet in SCI/SSCI/Pubmed

2025

Originalarbeit (Zeitschrift)

** Akhmetshina, A; Schooltink, L; Amor, M; Kuentzel, KB; Rainer, S; Nandy, A; Habisch, H; Madl, T; Rendina-Ruedy, E; Leithner, K; Vujić, N; Kratky, D Loss or inhibition of lysosomal acid lipase in vitro leads to cholesteryl ester accumulation without affecting muscle formation or mitochondrial function.
BBA Adv. 2025; 7: 100135 Doi: 10.1016/j.bbadva.2024.100135 [OPEN ACCESS]
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** Bourgeois, B; Madl, T Methods to Study Structure and Dynamics of FOXO Proteins.
Methods Mol Biol. 2025; 2871: 85-98. Doi: 10.1007/978-1-0716-4217-7_8
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** Okutan, B; Schwarze, UY; Habisch, H; Iskhakova, K; Ćwieka, H; Ribeiro-Machado, C; Moosmann, JP; Blanchet, C; Brcic, I; Santos, SG; Madl, T; Zeller-Plumhoff, B; Weinberg, AM; Wieland, DCF; Sommer, NG Biodegradable ultrahigh-purity magnesium and its alloy ZX00 promote osteogenesis in the medullary cavity and glycogenolysis in the liver.
Acta Biomater. 2025; Doi: 10.1016/j.actbio.2025.02.007
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** Olivos-Ramirez, GE; Cofas-Vargas, LF; Madl, T; Poma, AB Conformational and Stability Analysis of SARS-CoV-2 Spike Protein Variants by Molecular Simulation
PATHOGENS. 2025; 14(3): 274 Doi: 10.3390/pathogens14030274 [OPEN ACCESS]
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** Reiter, BF; Bordag, N; Schnoegl, D; Delbeck, M; Madl, T; Habisch, H; Kwapiszewska, G; Meding, J; Marsh, LM The Acrolein - Lipopolysaccharide Mouse Model for Frequent Exacerbations in COPD.
Am J Respir Cell Mol Biol. 2025; Doi: 10.1165/rcmb.2024-0507MA
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** Semmler, G; Baumgartner, C; Metz, M; Gensluckner, S; Habisch, H; Hofer, H; März, W; Offner, F; Völkerer, A; Petrenko, O; Wernly, B; Draxler-Dworzak, S; Neyer, M; Nigmann, C; Greber-Platzer, S; Esterbauer, H; Madl, T; Aigner, E; Scherer, T; Datz, C Lipid Dysregulation in Tangier Disease: A Case Series and Metabolic Characterization.
J Clin Endocrinol Metab. 2025; Doi: 10.1210/clinem/dgaf131
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** Zhou, Q; Sagmeister, T; Hutten, S; Bourgeois, B; Pavkov-Keller, T; Dormann, D; Madl, T Structural basis of phosphorylation-independent nuclear import of CIRBP by TNPO3.
Nat Commun. 2025; 16(1):4456 Doi: 10.1038/s41467-025-59802-2 [OPEN ACCESS]
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2024

Originalarbeit (Zeitschrift)

** Akhmetshina, A; Bianco, V; Bradić, I; Korbelius, M; Pirchheim, A; Kuentzel, KB; Eichmann, TO; Hinteregger, H; Kolb, D; Habisch, H; Liesinger, L; Madl, T; Sattler, W; Radović, B; Sedej, S; Birner-Gruenberger, R; Vujić, N; Kratky, D Loss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles of mice.
Mol Metab. 2024; 79:101869 Doi: 10.1016/j.molmet.2023.101869 [OPEN ACCESS]
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** Bradić, I; Vujić, N; Kuentzel, KB; Habisch, H; Pirchheim, A; Akhmetshina, A; Henderson, JD; Madl, T; Deshmukh, AS; Kratky, D Lanifibranor Reduces Inflammation and Improves Dyslipidemia in Lysosomal Acid Lipase-Deficient Mice.
Gastro Hep Adv. 2024; 3(6): 711-723. Doi: 10.1016/j.gastha.2024.05.006 [OPEN ACCESS]
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** Gil-Redondo, R; Conde, R; Bruzzone, C; Seco, ML; Bizkarguenaga, M; González-Valle, B; de, Diego, A; Laín, A; Habisch, H; Haudum, C; Verheyen, N; Obermayer-Pietsch, B; Margarita, S; Pelusi, S; Verde, I; Oliveira, N; Sousa, A; Zabala-Letona, A; Santos-Martin, A; Loizaga-Iriarte, A; Unda-Urzaiz, M; Kazenwadel, J; Berezhnoy, G; Geisler, T; Gawaz, M; Cannet, C; Schäfer, H; Diercks, T; Trautwein, C; Carracedo, A; Madl, T; Valenti, L; Spraul, M; Lu, SC; Embade, N; Mato, JM; Millet, O MetSCORE: a molecular metric to evaluate the risk of metabolic syndrome based on serum NMR metabolomics.
Cardiovasc Diabetol. 2024; 23(1): 272 Doi: 10.1186/s12933-024-02363-3 [OPEN ACCESS]
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** Hofer, SJ; Daskalaki, I; Bergmann, M; Friščić, J; Zimmermann, A; Mueller, MI; Abdellatif, M; Nicastro, R; Masser, S; Durand, S; Nartey, A; Waltenstorfer, M; Enzenhofer, S; Faimann, I; Gschiel, V; Bajaj, T; Niemeyer, C; Gkikas, I; Pein, L; Cerrato, G; Pan, H; Liang, Y; Tadic, J; Jerkovic, A; Aprahamian, F; Robbins, CE; Nirmalathasan, N; Habisch, H; Annerer, E; Dethloff, F; Stumpe, M; Grundler, F; Wilhelmi, de, Toledo, F; Heinz, DE; Koppold, DA; Rajput, Khokhar, A; Michalsen, A; Tripolt, NJ; Sourij, H; Pieber, TR; de, Cabo, R; McCormick, MA; Magnes, C; Kepp, O; Dengjel, J; Sigrist, SJ; Gassen, NC; Sedej, S; Madl, T; De, Virgilio, C; Stelzl, U; Hoffmann, MH; Eisenberg, T; Tavernarakis, N; Kroemer, G; Madeo, F Spermidine is essential for fasting-mediated autophagy and longevity.
Nat Cell Biol. 2024; 26(9):1571-1584 Doi: 10.1038/s41556-024-01468-x [OPEN ACCESS]
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** Hornegger, H; Anisimova, AS; Muratovic, A; Bourgeois, B; Spinetti, E; Niedermoser, I; Covino, R; Madl, T; Karagöz, GE IGF2BP1 phosphorylation in the disordered linkers regulates ribonucleoprotein condensate formation and RNA metabolism.
Nat Commun. 2024; 15(1): 9054 Doi: 10.1038/s41467-024-53400-4 [OPEN ACCESS]
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** Horvath, A; Habisch, H; Prietl, B; Pfeifer, V; Balazs, I; Kovacs, G; Foris, V; John, N; Kleinschek, D; Feldbacher, N; Grønbæk, H; Møller, HJ; Žukauskaitė, K; Madl, T; Stadlbauer, V Alteration of the Gut-Lung Axis After Severe COVID-19 Infection and Modulation Through Probiotics: A Randomized, Controlled Pilot Study.
Nutrients. 2024; 16(22): Doi: 10.3390/nu16223840 [OPEN ACCESS]
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** Horvath, A; Haller, R; Feldbacher, N; Habisch, H; Žukauskaitė, K; Madl, T; Stadlbauer, V Probiotic Therapy of Gastrointestinal Symptoms During COVID-19 Infection: A Randomized, Double-Blind, Placebo-Controlled, Remote Study.
Nutrients. 2024; 16(22): Doi: 10.3390/nu16223970 [OPEN ACCESS]
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** Šimunić, E; Podgorski, II; Pinterić, M; Hadžija, MP; Belužić, R; Paradžik, M; Dončević, L; Balog, T; Kaloper, M; Habisch, H; Madl, T; Korać, A; Sobočanec, S Sirtuin 3 drives sex-specific responses to age-related changes in mouse embryonic fibroblasts.
Mech Ageing Dev. 2024; 222: 111996 Doi: 10.1016/j.mad.2024.111996
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** Jonas, K; Prinz, F; Ferracin, M; Krajina, K; Deutsch, A; Madl, T; Rinner, B; Slaby, O; Klec, C; Pichler, M MiR-4646-5p Acts as a Tumor-Suppressive Factor in Triple Negative Breast Cancer and Targets the Cholesterol Transport Protein GRAMD1B.
Noncoding RNA. 2023; 10(1): Doi: 10.3390/ncrna10010002 [OPEN ACCESS]
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** Klobučar, I; Habisch, H; Klobučar, L; Trbušić, M; Pregartner, G; Berghold, A; Kostner, GM; Scharnagl, H; Madl, T; Frank, S; Degoricija, V Serum Levels of Adiponectin Are Strongly Associated with Lipoprotein Subclasses in Healthy Volunteers but Not in Patients with Metabolic Syndrome.
Int J Mol Sci. 2024; 25(9): Doi: 10.3390/ijms25095050 [OPEN ACCESS]
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** Klobučar, I; Habisch, H; Klobučar, L; Trbušić, M; Pregartner, G; Berghold, A; Kostner, GM; Scharnagl, H; Madl, T; Frank, S; Degoricija, V Sex-Related Differences in the Associations between Adiponectin and Serum Lipoproteins in Healthy Subjects and Patients with Metabolic Syndrome.
Biomedicines. 2024; 12(9): Doi: 10.3390/biomedicines12091972 [OPEN ACCESS]
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** Klobučar, I; Hofmann, L; Habisch, H; Lechleitner, M; Klobučar, L; Trbušić, M; Pregartner, G; Berghold, A; Madl, T; Frank, S; Degoricija, V Advanced Oxidation Protein Products Are Strongly Associated with the Serum Levels and Lipid Contents of Lipoprotein Subclasses in Healthy Volunteers and Patients with Metabolic Syndrome.
Antioxidants (Basel). 2024; 13(3): Doi: 10.3390/antiox13030339 [OPEN ACCESS]
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** Kreuzer, K; Birkl-Toeglhofer, AM; Haybaeck, J; Reiter, A; Dalkner, N; Fellendorf, FT; Maget, A; Platzer, M; Seidl, M; Mendel, LM; Lenger, M; Birner, A; Queissner, R; Mairinger, M; Obermayer, A; Kohlhammer-Dohr, A; Stross, TM; Häussl, A; Hamm, C; Schöggl, H; Amberger-Otti, D; Painold, A; Lahousen-Luxenberger, T; Leitner-Afschar, B; Färber, T; Mörkl, S; Wagner-Skacel, J; Meier-Allard, N; Lackner, S; Holasek, S; Habisch, H; Madl, T; Reininghaus, E; Bengesser, SA PROVIT-CLOCK: A Potential Influence of Probiotics and Vitamin B7 Add-On Treatment and Metabolites on Clock Gene Expression in Major Depression.
Neuropsychobiology. 2024; 83(3-4):135-151 Doi: 10.1159/000538781 [OPEN ACCESS]
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** Kumpitsch, C; Fischmeister, FPS; Lackner, S; Holasek, S; Madl, T; Habisch, H; Wolf, A; Schöpf, V; Moissl-Eichinger, C Reduced olfactory performance is associated with changed microbial diversity, oralization, and accumulation of dead biomaterial in the nasal olfactory area.
Microbiol Spectr. 2024; 12(2):e0154923 Doi: 10.1128/spectrum.01549-23 [OPEN ACCESS]
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** Lackner, S; Mahnert, A; Moissl-Eichinger, C; Madl, T; Habisch, H; Meier-Allard, N; Kumpitsch, C; Lahousen, T; Kohlhammer-Dohr, A; Mörkl, S; Strobl, H; Holasek, S Interindividual differences in aronia juice tolerability linked to gut microbiome and metabolome changes-secondary analysis of a randomized placebo-controlled parallel intervention trial.
Microbiome. 2024; 12(1): 49 Doi: 10.1186/s40168-024-01774-4 [OPEN ACCESS]
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** Lenihan-Geels, G; Garcia, Carrizo, F; Leer, M; Gohlke, S; Oster, M; Pöhle-Kronawitter, S; Ott, C; Chadt, A; Reinisch, IN; Galhuber, M; Li, C; Jonas, W; Jähnert, M; Klaus, S; Al-Hasani, H; Grune, T; Schürmann, A; Madl, T; Prokesch, A; Schupp, M; Schulz, TJ Skeletal muscle p53-depletion uncovers a mechanism of fuel usage suppression that enables efficient energy conservation.
J Cachexia Sarcopenia Muscle. 2024; Doi: 10.1002/jcsm.13529 [OPEN ACCESS]
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** Michenthaler, H; Duszka, K; Reinisch, I; Galhuber, M; Moyschewitz, E; Stryeck, S; Madl, T; Prokesch, A; Krstic, J Systemic and transcriptional response to intermittent fasting and fasting-mimicking diet in mice.
BMC Biol. 2024; 22(1): 268 Doi: 10.1186/s12915-024-02061-2 [OPEN ACCESS]
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** Neuss, T; Chen, MC; Wirges, N; Usluer, S; Oellinger, R; Lier, S; Dudek, M; Madl, T; Jastroch, M; Steiger, K; Schmitz, W; Einwächter, H; Schmid, RM Metabolic Reprogramming Is an Initial Step in Pancreatic Carcinogenesis That Can Be Targeted to Inhibit Acinar-to-Ductal Metaplasia
CANCER RES. 2024; 84(14): 2297-2312. Doi: 10.1158/0008-5472.CAN-23-2213
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** Pammer, A; Klobučar, I; Stadler, JT; Meissl, S; Habisch, H; Madl, T; Frank, S; Degoricija, V; Marsche, G Impaired HDL antioxidant and anti-inflammatory functions are linked to increased mortality in acute heart failure patients.
Redox Biol. 2024; 76:103341 Doi: 10.1016/j.redox.2024.103341 [OPEN ACCESS]
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** Pammer, A; Obermayer, A; Stadler, JT; Pferschy, PN; Tripolt, NJ; Habisch, H; Madl, T; Sourij, H; Marsche, G Effects of dietary interventions and intermittent fasting on HDL function in obese individuals with T2DM: a randomized controlled trial.
Cardiovasc Diabetol. 2024; 23(1): 339 Doi: 10.1186/s12933-024-02426-5 [OPEN ACCESS]
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** Pilic, J; Gottschalk, B; Bourgeois, B; Habisch, H; Koshenov, Z; Oflaz, FE; Erdogan, YC; Miri, SM; Yiğit, EN; Aydın, MŞ; Öztürk, G; Eroglu, E; Shoshan-Barmatz, V; Madl, T; Graier, WF; Malli, R Hexokinase 1 forms rings that regulate mitochondrial fission during energy stress.
Mol Cell. 2024; 84(14): 2732-2746.e5. Doi: 10.1016/j.molcel.2024.06.009
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** Stadler, JT; Bärnthaler, T; Borenich, A; Emrich, IE; Habisch, H; Rani, A; Holzer, M; Madl, T; Heine, GH; Marsche, G Low LCAT activity is linked to acute decompensated heart failure and mortality in patients with CKD.
J Lipid Res. 2024; 65(9):100624 Doi: 10.1016/j.jlr.2024.100624 [OPEN ACCESS]
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** Stadler, JT; Borenich, A; Pammer, A; Emrich, IE; Habisch, H; Madl, T; Heine, GH; Marsche, G Association of Small HDL Subclasses with Mortality Risk in Chronic Kidney Disease
ANTIOXIDANTS-BASEL. 2024; 13(12): 1511 Doi: 10.3390/antiox13121511 [OPEN ACCESS]
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** Tehlivets, O; Almer, G; Brunner, MS; Lechleitner, M; Sommer, G; Kolb, D; Leitinger, G; Diwoky, C; Wolinski, H; Habisch, H; Opriessnig, P; Bogoni, F; Pernitsch, D; Kavertseva, M; Bourgeois, B; Kukilo, J; Tehlivets, YG; Schwarz, AN; Züllig, T; Bubalo, V; Schauer, S; Groselj-Strele, A; Hoefler, G; Rechberger, GN; Herrmann, M; Eller, K; Rosenkranz, AR; Madl, T; Frank, S; Holzapfel, GA; Kratky, D; Mangge, H; Hörl, G Homocysteine contributes to atherogenic transformation of the aorta in rabbits in the absence of hypercholesterolemia.
BIOMED PHARMACOTHER. 2024; 178: 117244 Doi: 10.1016/j.biopha.2024.117244
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** Usluer, S; Galhuber, M; Khanna, Y; Bourgeois, B; Spreitzer, E; Michenthaler, H; Prokesch, A; Madl, T Disordered regions mediate the interaction of p53 and MRE11.
Biochim Biophys Acta Mol Cell Res. 2023; 1871(2): 119654 Doi: 10.1016/j.bbamcr.2023.119654
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** Wittmann, L; Eigenfeld, M; Büchner, K; Meiler, J; Habisch, H; Madl, T; Kerpes, R; Becker, T; Berensmeier, S; Schwaminger, SP Millifluidic magnetophoresis-based chip for age-specific fractionation: evaluating the impact of age on metabolomics and gene expression in yeast.
Lab Chip. 2024; 24(11):2987-2998 Doi: 10.1039/d4lc00185k [OPEN ACCESS]
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** Zhang, F; Bischof, H; Burgstaller, S; Bourgeois, BMR; Malli, R; Madl, T Genetically encoded fluorescent sensor to monitor intracellular arginine methylation.
J Photochem Photobiol B. 2024; 252: 112867 Doi: 10.1016/j.jphotobiol.2024.112867
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Übersichtsarbeit

** Madreiter-Sokolowski, CT; Hiden, U; Krstic, J; Panzitt, K; Wagner, M; Enzinger, C; Khalil, M; Abdellatif, M; Malle, E; Madl, T; Osto, E; Schosserer, M; Binder, CJ; Olschewski, A Targeting organ-specific mitochondrial dysfunction to improve biological aging.
Pharmacol Ther. 2024; 262:108710 Doi: 10.1016/j.pharmthera.2024.108710
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Abstract (Zeitschrift)

** Dormann, D; Sternburg, EL; Hutten, S; Kuhr, NS; Lenard, AJ; Jutzi, D; Ruepp, MD; Koenig, J; Madl, T RGG motifs govern subcellular localization and RNA-binding of FUS
BIOPHYS J. 2024; 123(3):1A-1A.-68th Annual Meeting of the Biophysical Society; FEB 10-14, 2024; Philadelphia, USA. [Oral Communication]
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** Fiorentino, F; Pignata, L; Arceci, E; Di Bello, E; Bonaldi, T; Barone, M; Madl, T; Jeyasekharan, A; Mattevi, A; Valente, S; Guccione, E; Mai, A Simultaneous targeting of LSD1 and PRMT5 through chimeric inhibitors as a novel therapeutic approach against leukemia
FEBS OPEN BIO. 2024; 14: 18-19.-FEBS Congress; JUN 29-JUL 3, 2024; Milan, ITALY. [Oral Communication]
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** Mooslechner, AA; Klötzer, KA; Habisch, H; Madl, T; Rosenkranz, AR; Bärnthaler, T; Eller, K Enhanced Renal Tissue Regeneration and Functional Recovery with IL-15 Treatment in Acute Kidney Injury
EUR J IMMUNOL. 2024; 54: 1560-1560.-7th European Conference of Immunology; SEP 01-04, 2024; Dublin, IRELAND. [Poster]
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** Rawal, S; Kolb, D; Pritisanac, I; Keller, TP; Desfosses, A; Madl, T; Alderson, TR Molecular Mechanism of Caspase-9 CARD Oligomerization Using Cryo-em and NMR Spectroscopy
PROTEIN SCI. 2024; 33: 155-155.
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2023

Originalarbeit (Zeitschrift)

** Abuja, PM; Pabst, D; Bourgeois, B; Loibner, M; Ulz, C; Kufferath, I; Fackelmann, U; Stumptner, C; Kraemer, R; Madl, T; Zatloukal, K Residual Humidity in Paraffin-Embedded Tissue Reduces Nucleic Acid Stability.
Int J Mol Sci. 2023; 24(9): Doi: 10.3390/ijms24098010 [OPEN ACCESS]
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** Aliwa, B; Horvath, A; Traub, J; Feldbacher, N; Habisch, H; Fauler, G; Madl, T; Stadlbauer, V Altered gut microbiome, bile acid composition and metabolome in sarcopenia in liver cirrhosis.
J Cachexia Sarcopenia Muscle. 2023; 14(6):2676-2691 Doi: 10.1002/jcsm.13342 [OPEN ACCESS]
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** Gui, T; Fleming, C; Manzato, C; Bourgeois, B; Sirati, N; Heuer, J; Papadionysiou, I; Montfort, DIV; Gijzen, MV; Smits, LMM; Burgering, BMT; Madl, T; Schuijers, J Targeted perturbation of signaling-driven condensates.
Mol Cell. 2023; 83(22): 4141-4157.e11. Doi: 10.1016/j.molcel.2023.10.023
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** Jonas, K; Prinz, F; Ferracin, M; Krajina, K; Pasculli, B; Deutsch, A; Madl, T; Rinner, B; Slaby, O; Klec, C; Pichler, M MiR-4649-5p acts as a tumor-suppressive microRNA in triple negative breast cancer by direct interaction with PIP5K1C, thereby potentiating growth-inhibitory effects of the AKT inhibitor capivasertib
BREAST CANCER RES. 2023; 25(1): 119 Doi: 10.1186/s13058-023-01716-2 [OPEN ACCESS]
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** Karner, C; Anders, I; Vejzovic, D; Szkandera, J; Scheipl, S; Deutsch, AJA; Weiss, L; Vierlinger, K; Kolb, D; Kühberger, S; Heitzer, E; Habisch, H; Zhang, F; Madl, T; Reininger-Gutmann, B; Liegl-Atzwanger, B; Rinner, B Targeting epigenetic features in clear cell sarcomas based on patient-derived cell lines.
J Transl Med. 2023; 21(1): 54 Doi: 10.1186/s12967-022-03843-4 [OPEN ACCESS]
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** Klobučar, I; Klobučar, L; Lechleitner, M; Trbušić, M; Pregartner, G; Berghold, A; Habisch, H; Madl, T; Frank, S; Degoricija, V Associations between Endothelial Lipase and Apolipoprotein B-Containing Lipoproteins Differ in Healthy Volunteers and Metabolic Syndrome Patients.
Int J Mol Sci. 2023; 24(13): 10681 Doi: 10.3390/ijms241310681 [OPEN ACCESS]
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** Klobučar, I; Stadler, JT; Klobučar, L; Lechleitner, M; Trbušić, M; Pregartner, G; Berghold, A; Habisch, H; Madl, T; Marsche, G; Frank, S; Degoricija, V Associations between Endothelial Lipase, High-Density Lipoprotein, and Endothelial Function Differ in Healthy Volunteers and Metabolic Syndrome Patients.
Int J Mol Sci. 2023; 24(3): Doi: 10.3390/ijms24032073 [OPEN ACCESS]
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** Klobučar, I; Vidović, L; Arih, I; Lechleitner, M; Pregartner, G; Berghold, A; Habisch, H; Madl, T; Frank, S; Degoricija, V Low Valine Serum Levels Predict Increased 1-Year Mortality in Acute Heart Failure Patients.
Biomolecules. 2023; 13(9): 1323 Doi: 10.3390/biom13091323 [OPEN ACCESS]
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** Neumann, CJ; Mahnert, A; Kumpitsch, C; Kiu, R; Dalby, MJ; Kujawska, M; Madl, T; Kurath-Koller, S; Urlesberger, B; Resch, B; Hall, LJ; Moissl-Eichinger, C Clinical NEC prevention practices drive different microbiome profiles and functional responses in the preterm intestine.
Nat Commun. 2023; 14(1):1349 Doi: 10.1038/s41467-023-36825-1 [OPEN ACCESS]
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** Obermayer, A; Tripolt, NJ; Pferschy, PN; Kojzar, H; Aziz, F; Müller, A; Schauer, M; Oulhaj, A; Aberer, F; Sourij, C; Habisch, H; Madl, T; Pieber, T; Obermayer-Pietsch, B; Stadlbauer, V; Sourij, H Efficacy and Safety of Intermittent Fasting in People With Insulin-Treated Type 2 Diabetes (INTERFAST-2)-A Randomized Controlled Trial.
Diabetes Care. 2023; 46(2):463-468 Doi: 10.2337/dc22-1622 [OPEN ACCESS]
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** Stadler, JT; Habisch, H; Prüller, F; Mangge, H; Bärnthaler, T; Kargl, J; Pammer, A; Holzer, M; Meissl, S; Rani, A; Madl, T; Marsche, G HDL-Related Parameters and COVID-19 Mortality: The Importance of HDL Function.
Antioxidants (Basel). 2023; 12(11): Doi: 10.3390/antiox12112009 [OPEN ACCESS]
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** Zhang, FR; Rakhimbekova, A; Lashley, T; Madl, T Brain regions show different metabolic and protein arginine methylation phenotypes in frontotemporal dementias and Alzheimer's disease
PROG NEUROBIOL. 2023; 221: 102400 Doi: 10.1016/j.pneurobio.2022.102400
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Abstract (Zeitschrift)

** Haller, R; Fürst, S; Woltsche, J; Gulden, L; Schwarzl, J; Traub, J; Feldbacher, N; Aliwa, B; Madl, T; Fauler, G; Horvath, A; Stadlbauer, V Phascolarctobacterium as a predictor for survival in cirrhotic patients
J HEPATOL. 2023; 78: S354-S354. [Poster]
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2022

Originalarbeit (Zeitschrift)

** Barth, DA; Stanzer, S; Spiegelberg, JA; Bauernhofer, T; Absenger, G; Szkandera, J; Gerger, A; Smolle, MA; Hutterer, GC; Ahyai, SA; Madl, T; Posch, F; Riedl, JM; Klec, C; Jost, PJ; Kargl, J; Stradner, MH; Pichler, M Patterns of Peripheral Blood B-Cell Subtypes Are Associated With Treatment Response in Patients Treated With Immune Checkpoint Inhibitors: A Prospective Longitudinal Pan-Cancer Study.
Front Immunol. 2022; 13:840207 Doi: 10.3389/fimmu.2022.840207 [OPEN ACCESS]
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** Bresilla, D; Habisch, H; Pritišanac, I; Zarse, K; Parichatikanond, W; Ristow, M; Madl, T; Madreiter-Sokolowski, CT The sex-specific metabolic signature of C57BL/6NRj mice during aging.
Sci Rep. 2022; 12(1):21050 Doi: 10.1038/s41598-022-25396-8 [OPEN ACCESS]
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** Degoricija, V; Klobučar, I; Potočnjak, I; Dokoza, Terešak, S; Vidović, L; Pregartner, G; Berghold, A; Habisch, H; Madl, T; Frank, S Cholesterol Content of Very-Low-Density Lipoproteins Is Associated with 1-Year Mortality in Acute Heart Failure Patients.
BIOMOLECULES. 2022; 12(10): Doi: 10.3390/biom12101542 [OPEN ACCESS]
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** Galhuber, M; Michenthaler, H; Heininger, C; Reinisch, I; Nössing, C; Krstic, J; Kupper, N; Moyschewitz, E; Auer, M; Heitzer, E; Ulz, P; Birner-Gruenberger, R; Liesinger, L; Lenihan-Geels, GN; Oster, M; Spreitzer, E; Zenezini, Chiozzi, R; Schulz, TJ; Schupp, M; Madl, T; Heck, AJR; Prokesch, A Complementary omics strategies to dissect p53 signaling networks under nutrient stress.
Cell Mol Life Sci. 2022; 79(6):326 Doi: 10.1007/s00018-022-04345-8 [OPEN ACCESS]
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** Haudum, CW; Kolesnik, E; Colantonio, C; Mursic, I; Url-Michitsch, M; Tomaschitz, A; Glantschnig, T; Hutz, B; Lind, A; Schweighofer, N; Reiter, C; Ablasser, K; Wallner, M; Tripolt, NJ; Pieske-Kraigher, E; Madl, T; Springer, A; Seidel, G; Wedrich, A; Zirlik, A; Krahn, T; Stauber, R; Pieske, B; Pieber, TR; Verheyen, N; Obermayer-Pietsch, B; Schmidt, A Cohort profile: 'Biomarkers of Personalised Medicine' (BioPersMed): a single-centre prospective observational cohort study in Graz/Austria to evaluate novel biomarkers in cardiovascular and metabolic diseases.
BMJ Open. 2022; 12(4):e058890 Doi: 10.1136/bmjopen-2021-058890 [OPEN ACCESS]
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** Horvath, A; Traub, J; Aliwa, B; Bourgeois, B; Madl, T; Stadlbauer, V Oral Intake of L-Ornithine-L-Aspartate Is Associated with Distinct Microbiome and Metabolome Changes in Cirrhosis.
NUTRIENTS. 2022; 14(4): Doi: 10.3390/nu14040748 [OPEN ACCESS]
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** Klobučar, I; Degoricija, V; Potočnjak, I; Trbušić, M; Pregartner, G; Berghold, A; Fritz-Petrin, E; Habisch, H; Madl, T; Frank, S HDL-apoA-II Is Strongly Associated with 1-Year Mortality in Acute Heart Failure Patients.
BIOMEDICINES. 2022; 10(7): Doi: 10.3390/biomedicines10071668 [OPEN ACCESS]
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** Kreuzer, K; Reiter, A; Birkl-Töglhofer, AM; Dalkner, N; Mörkl, S; Mairinger, M; Fleischmann, E; Fellendorf, F; Platzer, M; Lenger, M; Färber, T; Seidl, M; Birner, A; Queissner, R; Mendel, LS; Maget, A; Kohlhammer-Dohr, A; Häussl, A; Wagner-Skacel, J; Schöggl, H; Amberger-Otti, D; Painold, A; Lahousen-Luxenberger, T; Leitner-Afschar, B; Haybaeck, J; Habisch, H; Madl, T; Reininghaus, E; Bengesser, S The PROVIT Study-Effects of Multispecies Probiotic Add-on Treatment on Metabolomics in Major Depressive Disorder-A Randomized, Placebo-Controlled Trial.
Metabolites. 2022; 12(8): Doi: 10.3390/metabo12080770 [OPEN ACCESS]
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** Krstic, J; Reinisch, I; Schindlmaier, K; Galhuber, M; Riahi, Z; Berger, N; Kupper, N; Moyschewitz, E; Auer, M; Michenthaler, H; Nössing, C; Depaoli, MR; Ramadani-Muja, J; Usluer, S; Stryeck, S; Pichler, M; Rinner, B; Deutsch, AJA; Reinisch, A; Madl, T; Chiozzi, RZ; Heck, AJR; Huch, M; Malli, R; Prokesch, A Fasting improves therapeutic response in hepatocellular carcinoma through p53-dependent metabolic synergism.
Sci Adv. 2022; 8(3):eabh2635 Doi: 10.1126/sciadv.abh2635 [OPEN ACCESS]
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** Lenard, AJ; Zhou, Q; Madreiter-Sokolowski, C; Bourgeois, B; Habacher, H; Khanna, Y; Madl, T EGCG Promotes FUS Condensate Formation in a Methylation-Dependent Manner.
Cells. 2022; 11(4): Doi: 10.3390/cells11040592 [OPEN ACCESS]
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** Oster, M; Galhuber, M; Krstic, J; Steinhoff, JS; Lenihan-Geels, G; Wulff, S; Kiefer, MF; Petricek, KM; Wowro, SJ; Flores, RE; Yang, N; Li, C; Meng, Y; Reinisch, I; Sommerfeld, M; Weger, S; Habisch, H; Madl, T; Schulz, TJ; Prokesch, A; Schupp, M Hepatic p53 is regulated by transcription factor FOXO1 and acutely controls glycogen homeostasis.
J Biol Chem. 2022; 298(9):102287 Doi: 10.1016/j.jbc.2022.102287 [OPEN ACCESS]
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** Reinisch, I; Klymiuk, I; Michenthaler, H; Moyschewitz, E; Galhuber, M; Krstic, J; Domingo, M; Zhang, F; Karbiener, M; Vujić, N; Kratky, D; Schreiber, R; Schupp, M; Lenihan-Geels, G; Schulz, TJ; Malli, R; Madl, T; Prokesch, A p53 Regulates a miRNA-Fructose Transporter Axis in Brown Adipose Tissue Under Fasting.
Front Genet. 2022; 13: 913030 Doi: 10.3389/fgene.2022.913030 [OPEN ACCESS]
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** Spreitzer, E; Alderson, TR; Bourgeois, B; Eggenreich, L; Habacher, H; Brahmersdorfer, G; Pritišanac, I; Sánchez-Murcia, PA; Madl, T FOXO transcription factors differ in their dynamics and intra/intermolecular interactions.
Curr Res Struct Biol. 2022; 4:118-133 Doi: 10.1016/j.crstbi.2022.04.001 [OPEN ACCESS]
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** Streese, L; Habisch, H; Deiseroth, A; Carrard, J; Infanger, D; Schmidt-Trucksäss, A; Madl, T; Hanssen, H Lipoprotein Subclasses Independently Contribute to Subclinical Variance of Microvascular and Macrovascular Health.
MOLECULES. 2022; 27(15): Doi: 10.3390/molecules27154760 [OPEN ACCESS]
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** Zhang, F; Richter, G; Bourgeois, B; Spreitzer, E; Moser, A; Keilbach, A; Kotnik, P; Madl, T A General Small-Angle X-ray Scattering-Based Screening Protocol for Studying Physical Stability of Protein Formulations.
Pharmaceutics. 2021; 14(1): Doi: 10.3390/pharmaceutics14010069 [OPEN ACCESS]
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** Zhou, Q; Kerbl-Knapp, J; Zhang, F; Korbelius, M; Kuentzel, KB; Vujić, N; Akhmetshina, A; Hörl, G; Paar, M; Steyrer, E; Kratky, D; Madl, T Metabolomic Profiles of Mouse Tissues Reveal an Interplay between Aging and Energy Metabolism.
Metabolites. 2021; 12(1): Doi: 10.3390/metabo12010017 [OPEN ACCESS]
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** Zhou, Q; Zhang, F; Kerbl-Knapp, J; Korbelius, M; Kuentzel, KB; Vujić, N; Akhmetshina, A; Hörl, G; Paar, M; Steyrer, E; Kratky, D; Madl, T Phosphatidylethanolamine N-Methyltransferase Knockout Modulates Metabolic Changes in Aging Mice.
BIOMOLECULES. 2022; 12(9): Doi: 10.3390/biom12091270 [OPEN ACCESS]
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Übersichtsarbeit

** Lenard, AJ; Mulder, FAA; Madl, T Solvent paramagnetic relaxation enhancement as a versatile method for studying structure and dynamics of biomolecular systems
PROG NUCL MAG RES SP. 2022; 132: 113-139. Doi: 10.1016/j.pnmrs.2022.09.001
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Abstract (Zeitschrift)

** Aliwa, B; Feldbacher, N; Horvath, A; Traub, J; Madl, T; Fauler, G; Stadlbauer, V Altered gut microbiome, metabolome and bile acid composition in sarcopenia in liver cirrhosis
J HEPATOL. Abstracts of The International Liver Congress 2022. 2022; 77: S68-S68.-International Liver Congress; JUN 22-26, 2022; London, ENGLAND. [Oral Communication]
Web of Science

 

** El-Heliebi, A; Prietl, B; Mahdy-Ali, K; Purkart, TU; Gerlitz, L; Skofler, C; Stanzer, S; Franz, J; Harbusch, N; Madl, T; Widhalm, G; Rossler, K; Tomberger, M; Mattersdorfer, K; Kroneis, T; Oberhuber, M; Pieber, TR Next generation drug screening platform: generation of patient-derived cells for ex vivo drug response studies of gliomas
NEURO-ONCOLOGY. 2022; 24: -Brain Tumor Meeting 2022; May 19-20, 2022; Berlin, GERMANY. Doi: 10.1093/neuonc/noac174.180 [Poster]
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** El-Heliebi, A; Urbanic-Purkart, T; Mahdy-Ali, K; Skofler, C; Gerlitz, L; Stanzer, S; Franz, J; Harbusch, N; Madl, T; Widhalm, G; Rossler, K; Tomberger, M; Mattersdorfer, K; Kroneis, T; Oberhuber, M; Pieber, T; Prietl, B PATIENT-DERIVED CELLS FOR EX VIVO DRUG SCREENING STUDIES OF GLIOMAS
NEURO-ONCOLOGY. 2022; 24: 209-209.-27th Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO); NOV 16-20, 2022; Tampa, FL. [Poster]
Web of Science

 

** Madl, T; Kerbl-Knapp, J; Rainer, F; Douschan, P; Stadlbauer, V; Avian, A; Marsche, G; Claria, J; Stauber, RE A novel metabolomics-based prognostic model shows superior diagnostic accuracy than MELD in chronic liver failure
J HEPATOL. 2022; 77: S346-S346.-EASL Annual Meeting; JUN 22-26, 2022; London, UK. [Poster]
Web of Science

 

** Wagner, M; Jungwirth, E; Panzitt, K; Moore, D; Madl, T; Thallinger, G; Marschall, HU FXR binding and transcription in the liver is signficantly altered in obese patients with NAFLD
J HEPATOL. 2022; 77: S696-S697.-European Association for the Studies of the Liver - EASL; Jun 22-25, 2022; London, Great Britain. [Poster]
Web of Science

 

2021

Originalarbeit (Zeitschrift)

** Bischof, H; Burgstaller, S; Springer, A; Matt, L; Rauter, T; Bachkönig, OA; Schmidt, T; Groschner, K; Schindl, R; Madl, T; Plesnila, N; Lukowski, R; Graier, WF; Malli, R Potassium ions promote hexokinase-II dependent glycolysis.
iScience. 2021; 24(4): 102346-102346. Doi: 10.1016/j.isci.2021.102346 [OPEN ACCESS]
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** Bourgeois, B; Gui, TS; Hoogeboom, D; Hocking, HG; Richter, G; Spreitzer, E; Viertler, M; Richter, K; Madl, T; Burgering, BMT Multiple regulatory intrinsically disordered motifs control FOXO4 transcription factor binding and function
CELL REP. 2021; 36(4): 109446 Doi: 10.1016/j.celrep.2021.109446 [OPEN ACCESS]
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** Gubensäk, N; Schrank, E; Hartlmüller, C; Göbl, C; Falsone, FS; Becker, W; Wagner, GE; Pulido, S; Meyer, NH; Pavkov-Keller, T; Madl, T; Reidl, J; Zangger, K Structural and DNA-binding properties of the cytoplasmic domain of Vibrio cholerae transcription factor ToxR.
J Biol Chem. 2021; 297(4): 101167 Doi: 10.1016/j.jbc.2021.101167 [OPEN ACCESS]
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** Habisch, H; Zhang, F; Zhou, Q; Madl, T Exploring the Arginine Methylome by Nuclear Magnetic Resonance Spectroscopy.
JOVE-J VIS EXP. 2021; (178): Doi: 10.3791/63245
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** Hinteregger, B; Loeffler, T; Flunkert, S; Neddens, J; Bayer, TA; Madl, T; Hutter-Paier, B Metabolic, Phenotypic, and Neuropathological Characterization of the Tg4-42 Mouse Model for Alzheimer's Disease.
J ALZHEIMERS DIS. 2021; 80(3): 1151-1168. Doi: 10.3233/JAD-201204 [OPEN ACCESS]
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** Joshi, L; Plastira, I; Bernhart, E; Reicher, H; Koyani, CN; Madl, T; Madreiter-Sokolowski, C; Koshenov, Z; Graier, WF; Hallström, S; Sattler, W Lysophosphatidic Acid Induces Aerobic Glycolysis, Lipogenesis, and Increased Amino Acid Uptake in BV-2 Microglia.
Int J Mol Sci. 2021; 22(4): Doi: 10.3390/ijms22041968 [OPEN ACCESS]
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** Klionsky, DJ; Abdel-Aziz, AK; Abdelfatah, S; Abdellatif, M; Abdoli, A; Abel, S; Abeliovich, H; Abildgaard, MH; Abudu, YP; Acevedo-Arozena, A; Adamopoulos, IE; Adeli, K; Adolph, TE; Adornetto, A; Aflaki, E; Agam, G; Agarwal, A; Aggarwal, BB; Agnello, M; Agostinis, P; Agrewala, JN; Agrotis, A; Aguilar, PV; Ahmad, ST; Ahmed, ZM; Ahumada-Castro, U; Aits, S; Aizawa, S; Akkoc, Y; Akoumianaki, T; Akpinar, HA; Al-Abd, AM; Al-Akra, L; Al-Gharaibeh, A; Alaoui-Jamali, MA; Alberti, S; Alcocer-Gómez, E; Alessandri, C; Ali, M; Alim, Al-Bari, MA; Aliwaini, S; Alizadeh, J; Almacellas, E; Almasan, A; Alonso, A; Alonso, GD; Altan-Bonnet, N; Altieri, DC; Álvarez, ÉMC; Alves, S; Alves, da, Costa, C; Alzaharna, MM; Amadio, M; Amantini, C; Amaral, C; Ambrosio, S; Amer, AO; Ammanathan, V; An, Z; Andersen, SU; Andrabi, SA; Andrade-Silva, M; Andres, AM; Angelini, S; et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹.
AUTOPHAGY. 2021; 17(1): 1-382. Doi: 10.1080/15548627.2020.1797280 [OPEN ACCESS]
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** Kumpitsch, C; Fischmeister, FPS; Mahnert, A; Lackner, S; Wilding, M; Sturm, C; Springer, A; Madl, T; Holasek, S; Högenauer, C; Berg, IA; Schoepf, V; Moissl-Eichinger, C Reduced B12 uptake and increased gastrointestinal formate are associated with archaeome-mediated breath methane emission in humans.
Microbiome. 2021; 9(1):193 Doi: 10.1186/s40168-021-01130-w [OPEN ACCESS]
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** Lenard, AJ; Hutten, S; Zhou, Q; Usluer, S; Zhang, F; Bourgeois, BMR; Dormann, D; Madl, T Phosphorylation Regulates CIRBP Arginine Methylation, Transportin-1 Binding and Liquid-Liquid Phase Separation.
FRONT MOL BIOSCI. 2021; 8: 689687 Doi: 10.3389/fmolb.2021.689687 [OPEN ACCESS]
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** Liu, S; Hu, Q; Li, C; Zhang, F; Gu, H; Wang, X; Li, S; Xue, L; Madl, T; Zhang, Y; Zhou, L Wide-Range, Rapid, and Specific Identification of Pathogenic Bacteria by Surface-Enhanced Raman Spectroscopy.
ACS Sens. 2021; 6(8):2911-2919 Doi: 10.1021/acssensors.1c00641 [OPEN ACCESS]
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** Lohberger, B; Glänzer, D; Eck, N; Kerschbaum-Gruber, S; Mara, E; Deycmar, S; Madl, T; Kashofer, K; Georg, P; Leithner, A; Georg, D Activation of efficient DNA repair mechanisms after photon and proton irradiation of human chondrosarcoma cells.
Sci Rep. 2021; 11(1): 24116 Doi: 10.1038/s41598-021-03529-9 [OPEN ACCESS]
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** Reisinger, AC; Posch, F; Hackl, G; Marsche, G; Sourij, H; Bourgeois, B; Eller, K; Madl, T; Eller, P Branched-Chain Amino Acids Can Predict Mortality in ICU Sepsis Patients.
Nutrients. 2021; 13(9): Doi: 10.3390/nu13093106 [OPEN ACCESS]
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** Richter, G; Gui, T; Bourgeois, B; Koyani, CN; Ulz, P; Heitzer, E; von, Lewinski, D; Burgering, BMT; Malle, E; Madl, T β-catenin regulates FOXP2 transcriptional activity via multiple binding sites.
FEBS J. 2021; 288(10):3261-3284 Doi: 10.1111/febs.15656 [OPEN ACCESS]
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** Schilcher, I; Stadler, JT; Lechleitner, M; Hrzenjak, A; Berghold, A; Pregartner, G; Lhomme, M; Holzer, M; Korbelius, M; Reichmann, F; Springer, A; Wadsack, C; Madl, T; Kratky, D; Kontush, A; Marsche, G; Frank, S Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL.
Int J Mol Sci. 2021; 22(2): Doi: 10.3390/ijms22020719 [OPEN ACCESS]
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** Schmid, PWN; Lim, NCH; Peters, C; Back, KC; Bourgeois, B; Pirolt, F; Richter, B; Peschek, J; Puk, O; Amarie, OV; Dalke, C; Haslbeck, M; Weinkauf, S; Madl, T; Graw, J; Buchner, J Imbalances in the eye lens proteome are linked to cataract formation.
NAT STRUCT MOL BIOL. 2021; 28(2): 143-151. Doi: 10.1038/s41594-020-00543-9
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** Schroeder, S; Hofer, SJ; Zimmermann, A; Pechlaner, R; Dammbrueck, C; Pendl, T; Marcello, GM; Pogatschnigg, V; Bergmann, M; Müller, M; Gschiel, V; Ristic, S; Tadic, J; Iwata, K; Richter, G; Farzi, A; Üçal, M; Schäfer, U; Poglitsch, M; Royer, P; Mekis, R; Agreiter, M; Tölle, RC; Sótonyi, P; Willeit, J; Mairhofer, B; Niederkofler, H; Pallhuber, I; Rungger, G; Tilg, H; Defrancesco, M; Marksteiner, J; Sinner, F; Magnes, C; Pieber, TR; Holzer, P; Kroemer, G; Carmona-Gutierrez, D; Scorrano, L; Dengjel, J; Madl, T; Sedej, S; Sigrist, SJ; Rácz, B; Kiechl, S; Eisenberg, T; Madeo, F Dietary spermidine improves cognitive function.
Cell Rep. 2021; 35(2):108985-108985 Doi: 10.1016/j.celrep.2021.108985 [OPEN ACCESS]
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** Streese, L; Springer, AM; Deiseroth, A; Carrard, J; Infanger, D; Schmaderer, C; Schmidt-Trucksaess, A; Madl, T; Hanssen, H Metabolic profiling links cardiovascular risk and vascular end organ damage
ATHEROSCLEROSIS. 2021; 331: 45-53. Doi: 10.1016/j.atherosclerosis.2021.07.005 [OPEN ACCESS]
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** Usluer, S; Spreitzer, E; Bourgeois, B; Madl, T p53 Transactivation Domain Mediates Binding and Phase Separation with Poly-PR/GR.
Int J Mol Sci. 2021; 22(21): Doi: 10.3390/ijms222111431 [OPEN ACCESS]
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** Wahida, A; Müller, M; Hiergeist, A; Popper, B; Steiger, K; Branca, C; Tschurtschenthaler, M; Engleitner, T; Donakonda, S; De, Coninck, J; Öllinger, R; Pfautsch, MK; Müller, N; Silva, M; Usluer, S; Oberg, ET; Böttcher, JP; Pfarr, N; Anton, M; Slotta-Huspenina, JB; Nerlich, AG; Madl, T; Basic, M; Bleich, A; Berx, G; Ruland, J; Knolle, PA; Rad, R; Adolph, TE; Vandenabeele, P; Kanegane, H; Gessner, A; Jost, PJ; Yabal, M XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells.
Sci Immunol. 2021; 6(65): eabf7235 Doi: 10.1126/sciimmunol.abf7235
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** Zhang, F; Kerbl-Knapp, J; Akhmetshina, A; Korbelius, M; Kuentzel, KB; Vujić, N; Hörl, G; Paar, M; Kratky, D; Steyrer, E; Madl, T Tissue-Specific Landscape of Metabolic Dysregulation during Ageing.
Biomolecules. 2021; 11(2): Doi: 10.3390/biom11020235 [OPEN ACCESS]
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** Zhang, F; Kerbl-Knapp, J; Rodriguez Colman, MJ; Meinitzer, A; Macher, T; Vujic, N; Fasching, S; Jany-Luig, E; Korbelius, M; Kuentzel, KB; Mack, M; Akhmetshina, A; Pirchheim, A; Paar, M; Rinner, B; Hörl, G; Steyrer, E; Stelzl, U; Burgering, B; Eisenberg, T; Pertschy, B; Kratky, D; Madl, T. Global analysis of protein arginine methylation.
Cell reports methods. 2021; 1(2): Doi: 10.1016/j.crmeth.2021.100016 [OPEN ACCESS]
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** Zhang, F; Wang, Y; Chen, G; Li, Z; Xing, X; Putz-Bankuti, C; Stauber, RE; Liu, X; Madl, T Growing Human Hepatocellular Tumors Undergo a Global Metabolic Reprogramming.
Cancers (Basel). 2021; 13(8): Doi: 10.3390/cancers13081980 [OPEN ACCESS]
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** Zhou, Q; Usluer, S; Zhang, F; Lenard, AJ; Bourgeois, BMR; Madl, T ATP regulates RNA-driven cold inducible RNA binding protein phase separation.
PROTEIN SCI. 2021; 30(7): 1438-1453. Doi: 10.1002/pro.4123 [OPEN ACCESS]
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Übersichtsarbeit

** Neuwirt, E; Gorka, O; Saller, BS; Groß, CJ; Madl, T; Groß, O NLRP3 as a sensor of metabolism gone awry.
CURR OPIN BIOTECH. 2021; 68: 300-309. Doi: 10.1016/j.copbio.2021.03.009
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Korrektur

** Bischof, H; Burgstaller, S; Springer, A; Matt, L; Rauter, T; Bachkönig, OA; Schmidt, T; Groschner, K; Schindl, R; Madl, T; Plesnila, N; Lukowski, R; Graier, WF; Malli, R Erratum: Potassium ions promote hexokinase-II dependent glycolysis.
iScience. 2021; 24(5): 102468 Doi: 10.1016/j.isci.2021.102468 [OPEN ACCESS]
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Kommentar

** Madl, T Intracellular drug binding affinities by NMR.
ACTA CRYSTALLOGR D. 2021; 77(Pt 10): 1216-1217. Doi: 10.1107/S2059798321010135 [OPEN ACCESS]
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2020

Originalarbeit (Zeitschrift)

** Bourgeois, B; Hutten, S; Gottschalk, B; Hofweber, M; Richter, G; Sternat, J; Abou-Ajram, C; Göbl, C; Leitinger, G; Graier, WF; Dormann, D; Madl, T Nonclassical nuclear localization signals mediate nuclear import of CIRBP.
Proc Natl Acad Sci U S A. 2020; 117(15): 8503-8514. Doi: 10.1073/pnas.1918944117 [OPEN ACCESS]
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** Duchardt-Ferner, E; Juen, M; Bourgeois, B; Madl, T; Kreutz, C; Ohlenschläger, O; Wöhnert, J Structure of an RNA aptamer in complex with the fluorophore tetramethylrhodamine.
Nucleic Acids Res. 2020; 48(2):949-961 Doi: 10.1093/nar/gkz1113 [OPEN ACCESS]
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** Göbl, C; Morris, VK; van Dam, L; Visscher, M; Polderman, PE; Hartlmüller, C; de Ruiter, H; Hora, M; Liesinger, L; Birner-Gruenberger, R; Vos, HR; Reif, B; Madl, T; Dansen, TB Cysteine oxidation triggers amyloid fibril formation of the tumor suppressor p16^INK4A.
Redox Biol. 2020; 28: 101316-101316. Doi: 10.1016/j.redox.2019.101316 [OPEN ACCESS]
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** Hinteregger, B; Loeffler, T; Flunkert, S; Neddens, J; Birner-Gruenberger, R; Bayer, TA; Madl, T; Hutter-Paier, B Transgene integration causes RARB downregulation in homozygous Tg4-42 mice.
Sci Rep. 2020; 10(1): 6377-6377. Doi: 10.1038/s41598-020-63512-8 [OPEN ACCESS]
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** Hutten, S; Usluer, S; Bourgeois, B; Simonetti, F; Odeh, HM; Fare, CM; Czuppa, M; Hruska-Plochan, M; Hofweber, M; Polymenidou, M; Shorter, J; Edbauer, D; Madl, T; Dormann, D Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions.
Cell Rep. 2020; 33(12):108538-108538 Doi: 10.1016/j.celrep.2020.108538 [OPEN ACCESS]
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** Jha, S; Taschler, U; Domenig, O; Poglitsch, M; Bourgeois, B; Pollheimer, M; Pusch, LM; Malovan, G; Frank, S; Madl, T; Gruber, K; Zimmermann, R; Macheroux, P Dipeptidyl peptidase 3 modulates the renin-angiotensin system in mice.
J Biol Chem. 2020; 295(40):13711-13723 Doi: 10.1074/jbc.RA120.014183 [OPEN ACCESS]
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** Kolleritsch, S; Kien, B; Schoiswohl, G; Diwoky, C; Schreiber, R; Heier, C; Maresch, LK; Schweiger, M; Eichmann, TO; Stryeck, S; Krenn, P; Tomin, T; Schittmayer, M; Kolb, D; Rülicke, T; Hoefler, G; Wolinski, H; Madl, T; Birner-Gruenberger, R; Haemmerle, G Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice.
Cardiovasc Res. 2020; 116(2):339-352 Doi: 10.1093/cvr/cvz119 [OPEN ACCESS]
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** Pausan, MR; Kolovetsiou-Kreiner, V; Richter, GL; Madl, T; Giselbrecht, E; Obermayer-Pietsch, B; Weiss, EC; Jantscher-Krenn, E; Moissl-Eichinger, C Human Milk Oligosaccharides Modulate the Risk for Preterm Birth in a Microbiome-Dependent and -Independent Manner.
mSystems. 2020; 5(3): Doi: 10.1128/mSystems.00334-20 [OPEN ACCESS]
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** Shi, JP; Sun, X; Zheng, SH; Song, L; Zhang, FR; Madl, T; Zhang, Y; Zhang, HW; Hong, MC Tin-Doped Near-Infrared Persistent Luminescence Nanoparticles with Considerable Improvement of Biological Window Activation for Deep Tumor Photodynamic Therapy.
ACS APPL BIO MATER. 2020; 3(9): 5995-6004. Doi: 10.1021/acsabm.0c00644 [OPEN ACCESS]
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** Strandback, E; Lienhart, WD; Hromic-Jahjefendic, A; Bourgeois, B; Högler, A; Waltenstorfer, D; Winkler, A; Zangger, K; Madl, T; Gruber, K; Macheroux, P A small molecule chaperone rescues the stability and activity of a cancer-associated variant of NAD(P)H:quinone oxidoreductase 1 in vitro.
FEBS Lett. 2020; 594(3):424-438 Doi: 10.1002/1873-3468.13636 [OPEN ACCESS]
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** Uhl, FM; Chen, S; O'Sullivan, D; Edwards-Hicks, J; Richter, G; Haring, E; Andrieux, G; Halbach, S; Apostolova, P; Büscher, J; Duquesne, S; Melchinger, W; Sauer, B; Shoumariyeh, K; Schmitt-Graeff, A; Kreutz, M; Lübbert, M; Duyster, J; Brummer, T; Boerries, M; Madl, T; Blazar, BR; Groß, O; Pearce, EL; Zeiser, R Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans.
Sci Transl Med. 2020; 12(567): Doi: 10.1126/scitranslmed.abb8969 [OPEN ACCESS]
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Übersichtsarbeit

** Spreitzer, E; Usluer, S; Madl, T Probing Surfaces in Dynamic Protein Interactions.
J Mol Biol. 2020; 432(9):2949-2972 Doi: 10.1016/j.jmb.2020.02.032 [OPEN ACCESS]
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Korrektur

** Stekovic, S; Hofer, SJ; Tripolt, N; Aon, MA; Royer, P; Pein, L; Stadler, JT; Pendl, T; Prietl, B; Url, J; Schroeder, S; Tadic, J; Eisenberg, T; Magnes, C; Stumpe, M; Zuegner, E; Bordag, N; Riedl, R; Schmidt, A; Kolesnik, E; Verheyen, N; Springer, A; Madl, T; Sinner, F; de Cabo, R; Kroemer, G; Obermayer-Pietsch, B; Dengjel, J; Sourij, H; Pieber, TR; Madeo, F Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans.
Cell Metab. 2020; 31(4):878-881 Doi: 10.1016/j.cmet.2020.02.011 [OPEN ACCESS]
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2019

Originalarbeit (Zeitschrift)

** Bischof, H; Burgstaller, S; Vujic, N; Madl, T; Kratky, D; Graier, WF; Malli, R Purification and Application of Genetically Encoded Potassium Ion Indicators for Quantification of Potassium Ion Concentrations within Biological Samples.
Curr Protoc Chem Biol. 2019; 11(3): e71-e71. Doi: 10.1002/cpch.71 [OPEN ACCESS]
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** Burgstaller, S; Bischof, H; Gensch, T; Stryeck, S; Gottschalk, B; Ramadani-Muja, J; Eroglu, E; Rost, R; Balfanz, S; Baumann, A; Waldeck-Weiermair, M; Hay, JC; Madl, T; Graier, WF; Malli, R pH-Lemon, a Fluorescent Protein-Based pH Reporter for Acidic Compartments.
ACS Sens. 2019; 4(4): 883-891. Doi: 10.1021/acssensors.8b01599 [Poster] [OPEN ACCESS]
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** Gross, AS; Zimmermann, A; Pendl, T; Schroeder, S; Schoenlechner, H; Knittelfelder, O; Lamplmayr, L; Santiso, A; Aufschnaiter, A; Waltenstorfer, D; Ortonobes Lara, S; Stryeck, S; Kast, C; Ruckenstuhl, C; Hofer, SJ; Michelitsch, B; Woelflingseder, M; Müller, R; Carmona-Gutierrez, D; Madl, T; Büttner, S; Fröhlich, KU; Shevchenko, A; Eisenberg, T Acetyl-CoA carboxylase 1-dependent lipogenesis promotes autophagy downstream of AMPK.
J Biol Chem. 2019; 294(32): 12020-12039. Doi: 10.1074/jbc.RA118.007020 [OPEN ACCESS]
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** Günthner, R; Hanssen, H; Hauser, C; Angermann, S; Lorenz, G; Kemmner, S; Matschkal, J; Braunisch, MC; Kuechle, C; Renders, L; Moog, P; Wassertheurer, S; Baumann, M; Hammes, HP; Mayer, CC; Haller, B; Stryeck, S; Madl, T; Carbajo-Lozoya, J; Heemann, U; Kotliar, K; Schmaderer, C Impaired Retinal Vessel Dilation Predicts Mortality in End-Stage Renal Disease.
Circ Res. 2019; Doi: 10.1161/CIRCRESAHA.118.314318 [OPEN ACCESS]
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** Hartlmüller, C; Spreitzer, E; Göbl, C; Falsone, F; Madl, T NMR characterization of solvent accessibility and transient structure in intrinsically disordered proteins.
J BIOMOL NMR. 2019; 73(6-7): 305-317. Doi: 10.1007/s10858-019-00248-2 [OPEN ACCESS]
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** Huber, K; Hofer, DC; Trefely, S; Pelzmann, HJ; Madreiter-Sokolowski, C; Duta-Mare, M; Schlager, S; Trausinger, G; Stryeck, S; Graier, WF; Kolb, D; Magnes, C; Snyder, NW; Prokesch, A; Kratky, D; Madl, T; Wellen, KE; Bogner-Strauss, JG N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes.
Biochim Biophys Acta Mol Cell Res. 2019; 1866(3): 337-348. Doi: 10.1016/j.bbamcr.2018.08.017 [OPEN ACCESS]
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** Klec, C; Madreiter-Sokolowski, CT; Stryeck, S; Sachdev, V; Duta-Mare, M; Gottschalk, B; Depaoli, MR; Rost, R; Hay, J; Waldeck-Weiermair, M; Kratky, D; Madl, T; Malli, R; Graier, WF Glycogen Synthase Kinase 3 Beta Controls Presenilin-1-Mediated Endoplasmic Reticulum Ca²⁺ Leak Directed to Mitochondria in Pancreatic Islets and β-Cells.
Cell Physiol Biochem. 2019; 52(1): 57-75. Doi: 10.33594/000000005 [OPEN ACCESS]
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** Klec, C; Madreiter-Sokolowski, CT; Ziomek, G; Stryeck, S; Sachdev, V; Duta-Mare, M; Gottschalk, B; Depaoli, MR; Rost, R; Hay, J; Waldeck-Weiermair, M; Kratky, D; Madl, T; Malli, R; Graier, WF Presenilin-1 Established ER-Ca²⁺ Leak: a Follow Up on Its Importance for the Initial Insulin Secretion in Pancreatic Islets and β-Cells upon Elevated Glucose.
Cell Physiol Biochem. 2019; 53(3): 573-586. Doi: 10.33594/000000158 [OPEN ACCESS]
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** Koch, K; Strandback, E; Jha, S; Richter, G; Bourgeois, B; Madl, T; Macheroux, P Oxidative stress-induced structural changes in the microtubule-associated flavoenzyme Irc15p from Saccharomyces cerevisiae.
Protein Sci. 2019; 28(1):176-190 Doi: 10.1002/pro.3517 [OPEN ACCESS]
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** Madreiter-Sokolowski, CT; Waldeck-Weiermair, M; Bourguignon, MP; Villeneuve, N; Gottschalk, B; Klec, C; Stryeck, S; Radulovic, S; Parichatikanond, W; Frank, S; Madl, T; Malli, R; Graier, WF Enhanced inter-compartmental Ca²⁺ flux modulates mitochondrial metabolism and apoptotic threshold during aging.
Redox Biol. 2019; 20:458-466 Doi: 10.1016/j.redox.2018.11.003 [OPEN ACCESS]
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** Merle, DA; Witternigg, A; Tam-Amersdorfer, C; Hartlmüller, C; Spreitzer, E; Schrank, E; Wagner-Lichtenegger, S; Werzer, O; Zangger, K; Kungl, AJ; Madl, T; Meyer, NH; Falsone, SF Increased Aggregation Tendency of Alpha-Synuclein in a Fully Disordered Protein Complex.
J Mol Biol. 2019; 431(14): 2581-2598. Doi: 10.1016/j.jmb.2019.04.031
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** Schilcher, I; Ledinski, G; Radulović, S; Hallström, S; Eichmann, T; Madl, T; Zhang, F; Leitinger, G; Kolb-Lenz, D; Darnhofer, B; Birner-Gruenberger, R; Wadsack, C; Kratky, D; Marsche, G; Frank, S; Cvirn, G Endothelial lipase increases antioxidative capacity of high-density lipoprotein.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(10):1363-1374 Doi: 10.1016/j.bbalip.2019.06.011 [OPEN ACCESS]
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** Schopf, FH; Huber, EM; Dodt, C; Lopez, A; Biebl, MM; Rutz, DA; Mühlhofer, M; Richter, G; Madl, T; Sattler, M; Groll, M; Buchner, J The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2.
MOL CELL. 2019; 74(1): 73-87. Doi: 10.1016/j.molcel.2019.02.011 [OPEN ACCESS]
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** Stadlbauer, V; Horvath, A; Komarova, I; Schmerboeck, B; Feldbacher, N; Wurm, S; Klymiuk, I; Durdevic, M; Rainer, F; Blesl, A; Stryeck, S; Madl, T; Stiegler, P; Leber, B A single alcohol binge impacts on neutrophil function without changes in gut barrier function and gut microbiome composition in healthy volunteers.
PLoS One. 2019; 14(2):e0211703-e0211703 Doi: 10.1371/journal.pone.0211703 [OPEN ACCESS]
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** Stekovic, S; Hofer, SJ; Tripolt, N; Aon, MA; Royer, P; Pein, L; Stadler, JT; Pendl, T; Prietl, B; Url, J; Schroeder, S; Tadic, J; Eisenberg, T; Magnes, C; Stumpe, M; Zuegner, E; Bordag, N; Riedl, R; Schmidt, A; Kolesnik, E; Verheyen, N; Springer, A; Madl, T; Sinner, F; de Cabo, R; Kroemer, G; Obermayer-Pietsch, B; Dengjel, J; Sourij, H; Pieber, TR; Madeo, F Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans.
Cell Metab. 2019; 30(3):462-476 Doi: 10.1016/j.cmet.2019.07.016 [OPEN ACCESS]
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** Stryeck, S; Gastrager, M; Degoricija, V; Trbušić, M; Potočnjak, I; Radulović, B; Pregartner, G; Berghold, A; Madl, T; Frank, S Serum Concentrations of Citrate, Tyrosine, 2- and 3- Hydroxybutyrate are Associated with Increased 3-Month Mortality in Acute Heart Failure Patients.
Sci Rep. 2019; 9(1): 6743-6743. Doi: 10.1038/s41598-019-42937-w [OPEN ACCESS]
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Abstract (Zeitschrift)

** Keilbach, A; Brousseau, JL; Madl, T Integrating SAXS and Complementary Techniques for Structure Determination of Biomolecules
ACTA CRYSTALLOGR A. 2019; 75: A432-A432. Doi: 10.1107/S0108767319095813 [OPEN ACCESS]
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** Stryeck, S; Voortman, M; Enzinger, C; Fuchs, S; Deisenhammer, F; Hegen, H; Fazekas, F; Madl, T; Khalil, M Serum NMR spectroscopy metabolomic profiles indicate progressive multiple sclerosis
EUR J NEUROL. 2019; 26: 241-241. [Poster]
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2018

Originalarbeit (Zeitschrift)

** Alkan, HF; Walter, KE; Luengo, A; Madreiter-Sokolowski, CT; Stryeck, S; Lau, AN; Al-Zoughbi, W; Lewis, CA; Thomas, CJ; Hoefler, G; Graier, WF; Madl, T; Vander Heiden, MG; Bogner-Strauss, JG Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting.
Cell Metab. 2018; 28(5):706-720 Doi: 10.1016/j.cmet.2018.07.021 [OPEN ACCESS]
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** Cristóvão, JS; Morris, VK; Cardoso, I; Leal, SS; Martínez, J; Botelho, HM; Göbl, C; David, R; Kierdorf, K; Alemi, M; Madl, T; Fritz, G; Reif, B; Gomes, CM The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation.
SCI ADV. 2018; 4(6): eaaq1702-eaaq1702. Doi: 10.1126/sciadv.aaq1702 [OPEN ACCESS]
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** Hofweber, M; Hutten, S; Bourgeois, B; Spreitzer, E; Niedner-Boblenz, A; Schifferer, M; Ruepp, MD; Simons, M; Niessing, D; Madl, T; Dormann, D Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Cell. 2018; 173(3):706-719 Doi: 10.1016/j.cell.2018.03.004 [OPEN ACCESS]
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** Koyani, CN; Trummer, C; Shrestha, N; Scheruebel, S; Bourgeois, B; Plastira, I; Kickmaier, S; Sourij, H; Rainer, PP; Madl, T; Sattler, W; Pelzmann, B; Malle, E; von Lewinski, D Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes.
Front Physiol. 2018; 9:1622-1622 Doi: 10.3389/fphys.2018.01622 [OPEN ACCESS]
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** Lorenz, G; Mayer, CC; Bachmann, Q; Stryeck, S; Braunisch, MC; Haller, B; Carbajo-Lozoya, J; Schmidt, A; Witthauer, S; Abuzahu, J; Kemmner, S; Angermann, S; Koneru, N; Wassertheurer, S; Bieber, R; Heemann, U; Madl, T; Pasch, A; Schmaderer, C Acetate-free, citrate-acidified bicarbonate dialysis improves serum calcification propensity-a preliminary study.
Nephrol Dial Transplant. 2018; 33(11): 2043-2051. Doi: 10.1093/ndt/gfy134
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** Pollheimer, MJ; Racedo, S; Mikels-Vigdal, A; Marshall, D; Bowlus, C; Lackner, C; Madl, T; Karlsen, TH; Hov, JR; Lyman, SK; Adamkewicz, J; Smith, V; Moreau, E; Zollner, G; Eide, TJ; Stojakovic, T; Scharnagl, H; Gruber, HJ; Stauber, RE; Trauner, M; Fickert, P Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis.
J Hepatol. 2018; 69(2):368-377 Doi: 10.1016/j.jhep.2018.04.009
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** Rutz, DA; Luo, Q; Freiburger, L; Madl, T; Kaila, VRI; Sattler, M; Buchner, J A switch point in the molecular chaperone Hsp90 responding to client interaction.
NAT COMMUN. 2018; 9(1): 1472-1472. Doi: 10.1038/s41467-018-03946-x [OPEN ACCESS]
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** Stryeck, S; Horvath, A; Leber, B; Stadlbauer, V; Madl, T NMR spectroscopy enables simultaneous quantification of carbohydrates for diagnosis of intestinal and gastric permeability.
Sci Rep. 2018; 8(1): 14650-14650. Doi: 10.1038/s41598-018-33104-8 [OPEN ACCESS]
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Übersichtsarbeit

** Bourgeois, B; Madl, T Regulation of cellular senescence via the FOXO4-p53 axis.
FEBS Lett. 2018; 592(12):2083-2097 Doi: 10.1002/1873-3468.13057 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Bourgeois, B; Burgering, B; Madl, T Unravelling the role of FOXO proteins in ageing and disease
FEBS OPEN BIO. 2018; 8: 46-46. [Poster]
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** Rainer, F; Horvath, A; Bashir, M; Leber, B; Schmerboeck, B; Blesl, A; Madl, T; Klymiuk, I; Groselj-Strele, A; Durdevic, M; Gronbaek, H; Moller, HJ; Freedber, DE; Abrams, JA; Stauber, RE; Fickert, P; Stiegler, P; Stadlbauer, V Loss of colonization resistance in cirrhosis facilitates proton pump inhibitor-associated oralization of the colonic microbiome
J HEPATOL. 2018; 68: S700-S700.-International Liver Congress (ILC); APR 11-15, 2018; Paris, FRANCE. Doi: 10.1016/S0168-8278(18)31663-5 [Poster]
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** Uhl, FM; Chen, S; O'Sullivan, D; Buck, M; Buscher, J; Pfeifer, D; Finke, J; Duyster, J; Bertz, H; Shoumariyeh, K; Borries, M; Richter, G; Madl, T; Pearce, EL; Zeiser, R Metabolic Reprogramming Overcomes T Cell Inhibition By AML Cells
BLOOD. 2018; 132: -60th Annual Meeting of the American-Society-of-Hematology (ASH); DEC 01-04, 2018; San Diego, CA. Doi: 10.1182/blood-2018-99-112897 [Poster]
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2017

Originalarbeit (Zeitschrift)

** Baar, MP; Brandt, RMC; Putavet, DA; Klein, JDD; Derks, KWJ; Bourgeois, BRM; Stryeck, S; Rijksen, Y; van Willigenburg, H; Feijtel, DA; van der Pluijm, I; Essers, J; van Cappellen, WA; van IJcken, WF; Houtsmuller, AB; Pothof, J; de Bruin, RWF; Madl, T; Hoeijmakers, JHJ; Campisi, J; de Keizer, PLJ Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Cell. 2017; 169(1):132-147 Doi: 10.1016/j.cell.2017.02.031 [OPEN ACCESS]
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** Bischof, H; Rehberg, M; Stryeck, S; Artinger, K; Eroglu, E; Waldeck-Weiermair, M; Gottschalk, B; Rost, R; Deak, AT; Niedrist, T; Vujic, N; Lindermuth, H; Prassl, R; Pelzmann, B; Groschner, K; Kratky, D; Eller, K; Rosenkranz, AR; Madl, T; Plesnila, N; Graier, WF; Malli, R Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo.
Nat Commun. 2017; 8(1):1422-1422 Doi: 10.1038/s41467-017-01615-z [OPEN ACCESS]
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** Bomblies, R; Luitz, MP; Scanu, S; Madl, T; Zacharias, M Transient helicity in intrinsically disordered Axin-1 studied by NMR spectroscopy and molecular dynamics simulations.
PLoS One. 2017; 12(3):e0174337-e0174337 Doi: 10.1371/journal.pone.0174337 [OPEN ACCESS]
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** Emmanouilidis, L; Schütz, U; Tripsianes, K; Madl, T; Radke, J; Rucktäschel, R; Wilmanns, M; Schliebs, W; Erdmann, R; Sattler, M Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19.
Nat Commun. 2017; 8(7):14635-14635 Doi: 10.1038/ncomms14635 [OPEN ACCESS]
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** Gourinchas, G; Etzl, S; Göbl, C; Vide, U; Madl, T; Winkler, A Long-range allosteric signaling in red light-regulated diguanylyl cyclases.
SCI ADV. 2017; 3(3): e1602498-e1602498. Doi: 10.1126/sciadv.1602498 [OPEN ACCESS]
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** Hartlmüller, C; Günther, JC; Wolter, AC; Wöhnert, J; Sattler, M; Madl, T RNA structure refinement using NMR solvent accessibility data.
Sci Rep. 2017; 7(1):5393-5393 Doi: 10.1038/s41598-017-05821-z [OPEN ACCESS]
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** Lienhart, WD; Strandback, E; Gudipati, V; Koch, K; Binter, A; Uhl, MK; Rantasa, DM; Bourgeois, B; Madl, T; Zangger, K; Gruber, K; Macheroux, P Catalytic competence, structure and stability of the cancer-associated R139W variant of the human NAD(P)H:quinone oxidoreductase 1 (NQO1).
FEBS J. 2017; 284(8):1233-1245 Doi: 10.1111/febs.14051 [OPEN ACCESS]
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** Öster, C; Kosol, S; Hartlmüller, C; Lamley, JM; Iuga, D; Oss, A; Org, ML; Vanatalu, K; Samoson, A; Madl, T; Lewandowski, JR Characterization of Protein-Protein Interfaces in Large Complexes by Solid-State NMR Solvent Paramagnetic Relaxation Enhancements.
J Am Chem Soc. 2017; 139(35):12165-12174 Doi: 10.1021/jacs.7b03875 [OPEN ACCESS]
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** Prokesch, A; Graef, FA; Madl, T; Kahlhofer, J; Heidenreich, S; Schumann, A; Moyschewitz, E; Pristoynik, P; Blaschitz, A; Knauer, M; Muenzner, M; Bogner-Strauss, JG; Dohr, G; Schulz, TJ; Schupp, M Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.
FASEB J. 2017; 31(2):732-742 Doi: 10.1096/fj.201600845R [OPEN ACCESS]
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** Rodriguez Camargo, DC; Tripsianes, K; Buday, K; Franko, A; Göbl, C; Hartlmüller, C; Sarkar, R; Aichler, M; Mettenleiter, G; Schulz, M; Böddrich, A; Erck, C; Martens, H; Walch, AK; Madl, T; Wanker, EE; Conrad, M; de Angelis, MH; Reif, B The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes.
SCI REP-UK. 2017; 7(6): 44041-44041. Doi: 10.1038/srep44041 [OPEN ACCESS]
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Kurzbericht/Letter

** Göbl, C; Focke-Tejkl, M; Najafi, N; Schrank, E; Madl, T; Kosol, S; Madritsch, C; Dorofeeva, Y; Flicker, S; Thalhamer, J; Valenta, R; Zangger, K; Tjandra, N Flexible IgE epitope-containing domains of Phl p 5 cause high allergenic activity.
J ALLERGY CLIN IMMUN. 2017; 140(4): 1187-1191. Doi: 10.1016/j.jaci.2017.05.005 [OPEN ACCESS]
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Übersichtsarbeit

** Stryeck, S; Birner-Gruenberger, R; Madl, T Integrative metabolomics as emerging tool to study autophagy regulation.
Microb Cell. 2017; 4(8):240-258 Doi: 10.15698/mic2017.08.584 [OPEN ACCESS]
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Editorial

** Madl, T Patchy proteins form a perfect lens.
SCIENCE. 2017; 357(6351): 546-547. Doi: 10.1126/science.aao1456 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Cristovao, JS; Morris, V; Cardoso, I; Leal, SS; Botelho, HM; Gobl, C; Kierdorf, K; Madl, T; Fritz, G; Reif, B; Gomes, CM The neuronal S100B cytokine targeting amyloid-beta aggregation in Alzheimer's disease
FEBS J. 2017; 284: 184-184.-42nd Congress of the Federation-of-European-Biochemical-Societies (FEBS) on From Molecules to Cells and Back; SEP 10-14, 2017; Jerusalem, ISRAEL. [Poster]
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** Schilcher, I; Kern, S; Madl, T; Eichmann, T; Ledinski, G; Hallstrom, S; Marsche, G; Frank, S EL-HDL EXHIBITS INCREASED CAPACITY TO ATTENUATE LDL OXIDATION INDEPENDENT OF PON1
ATHEROSCLEROSIS. 2017; 263: E216-E216.-85th Congress of the European-Atherosclerosis-Society (EAS); APR 23-26, 2017; Prague, CZECH REPUBLIC. Doi: 10.1016/j.atherosclerosis.2017.06.703 [Poster]
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2016

Originalarbeit (Zeitschrift)

** Anvarian, Z; Nojima, H; van Kappel, EC; Madl, T; Spit, M; Viertler, M; Jordens, I; Low, TY; van Scherpenzeel, RC; Kuper, I; Richter, K; Heck, AJ; Boelens, R; Vincent, JP; Rüdiger, SG; Maurice, MM Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.
Nat Struct Mol Biol. 2016; 23(4):324-332 Doi: 10.1038/nsmb.3191
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** Göbl, C; Resch, M; Strickland, M; Hartlmüller, C; Viertler, M; Tjandra, N; Madl, T Increasing the Chemical-Shift Dispersion of Unstructured Proteins with a Covalent Lanthanide Shift Reagent.
Angew Chem Int Ed Engl. 2016; 55(47):14847-14851 Doi: 10.1002/anie.201607261 [OPEN ACCESS]
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** Hartlmüller, C; Göbl, C; Madl, T Prediction of Protein Structure Using Surface Accessibility Data.
Angew Chem Int Ed Engl. 2016; 55(39):11970-11974 Doi: 10.1002/anie.201604788 [OPEN ACCESS]
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** Horvath, A; Leber, B; Schmerboeck, B; Tawdrous, M; Zettel, G; Hartl, A; Madl, T; Stryeck, S; Fuchs, D; Lemesch, S; Douschan, P; Krones, E; Spindelboeck, W; Durchschein, F; Rainer, F; Zollner, G; Stauber, RE; Fickert, P; Stiegler, P; Stadlbauer, V Randomised clinical trial: the effects of a multispecies probiotic vs. placebo on innate immune function, bacterial translocation and gut permeability in patients with cirrhosis.
Aliment Pharmacol Ther. 2016; 44(9):926-935 Doi: 10.1111/apt.13788 [OPEN ACCESS]
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** Janowski, R; Scanu, S; Niessing, D; Madl, T Crystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4.
Acta Crystallogr F Struct Biol Commun. 2016; 72(Pt 10):743-749 Doi: 10.1107/S2053230X16013686 [OPEN ACCESS]
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** Madreiter-Sokolowski, CT; Klec, C; Parichatikanond, W; Stryeck, S; Gottschalk, B; Pulido, S; Rost, R; Eroglu, E; Hofmann, NA; Bondarenko, AI; Madl, T; Waldeck-Weiermair, M; Malli, R; Graier, WF PRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca(2+) uptake in immortalized cells.
Nat Commun. 2016; 7(4):12897-12897 Doi: 10.1038/ncomms12897 [OPEN ACCESS]
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** Radović, B; Vujić, N; Leopold, C; Schlager, S; Goeritzer, M; Patankar, JV; Korbelius, M; Kolb, D; Reindl, J; Wegscheider, M; Tomin, T; Birner-Gruenberger, R; Schittmayer, M; Groschner, L; Magnes, C; Diwoky, C; Frank, S; Steyrer, E; Du, H; Graier, WF; Madl, T; Kratky, D Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice.
Diabetologia. 2016; 59(8):1743-1752 Doi: 10.1007/s00125-016-3968-6 [OPEN ACCESS]
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** Suárez-Calvet, M; Neumann, M; Arzberger, T; Abou-Ajram, C; Funk, E; Hartmann, H; Edbauer, D; Kremmer, E; Göbl, C; Resch, M; Bourgeois, B; Madl, T; Reber, S; Jutzi, D; Ruepp, MD; Mackenzie, IR; Ansorge, O; Dormann, D; Haass, C Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS.
Acta Neuropathol. 2016; 131(4):587-604 Doi: 10.1007/s00401-016-1544-2 [OPEN ACCESS]
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** Voith von Voithenberg, L; Sánchez-Rico, C; Kang, HS; Madl, T; Zanier, K; Barth, A; Warner, LR; Sattler, M; Lamb, DC Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift.
Proc Natl Acad Sci U S A. 2016; 113(46):E7169-E7175 Doi: 10.1073/pnas.1605873113 [OPEN ACCESS]
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** Weber, J; Bao, H; Hartlmüller, C; Wang, Z; Windhager, A; Janowski, R; Madl, T; Jin, P; Niessing, D Structural basis of nucleic-acid recognition and double-strand unwinding by the essential neuronal protein Pur-alpha.
Elife. 2016; 5(7): Doi: 10.7554/eLife.11297 [OPEN ACCESS]
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** Zierer, BK; Rübbelke, M; Tippel, F; Madl, T; Schopf, FH; Rutz, DA; Richter, K; Sattler, M; Buchner, J Importance of cycle timing for the function of the molecular chaperone Hsp90.
Nat Struct Mol Biol. 2016; 23(11):1020-1028 Doi: 10.1038/nsmb.3305 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Duta-Mare, MC; Radovic, B; Schlager, S; Wegscheider, M; Kolb-Lenz, D; Madl, T; Stryeck, S; Kratky, D CONSEQUENCES OF LYSOSOMAL ACID LIPASE DEFICIENCY IN MACROPHAGES
ATHEROSCLEROSIS. 2016; 252: E226-E226.-Congress of the European-Atherosclerosis-Society (EAS); MAY 29-JUN 01, 2016; Innsbruck, AUSTRIA. Doi: 10.1016/j.atherosclerosis.2016.07.201 [Oral Communication]
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2015

Originalarbeit (Zeitschrift)

** Chromikova, V; Mader, A; Hofbauer, S; Göbl, C; Madl, T; Gach, JS; Bauernfried, S; Furtmüller, PG; Forthal, DN; Mach, L; Obinger, C; Kunert, R Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM.
Biochim Biophys Acta. 2015; 1854(10 Pt A):1536-1544 Doi: 10.1016/j.bbapap.2015.02.018 [OPEN ACCESS]
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** Gersch, M; Famulla, K; Dahmen, M; Göbl, C; Malik, I; Richter, K; Korotkov, VS; Sass, P; Rübsamen-Schaeff, H; Madl, T; Brötz-Oesterhelt, H; Sieber, SA AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control.
Nat Commun. 2015; 6(2):6320-6320 Doi: 10.1038/ncomms7320 [OPEN ACCESS]
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** Hacker, C; Christ, NA; Duchardt-Ferner, E; Korn, S; Göbl, C; Berninger, L; Düsterhus, S; Hellmich, UA; Madl, T; Kötter, P; Entian, KD; Wöhnert, J The Solution Structure of the Lantibiotic Immunity Protein NisI and Its Interactions with Nisin.
J Biol Chem. 2015; 290(48):28869-28886 Doi: 10.1074/jbc.M115.679969 [OPEN ACCESS]
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** Haslbeck, V; Eckl, JM; Drazic, A; Rutz, DA; Lorenz, OR; Zimmermann, K; Kriehuber, T; Lindemann, C; Madl, T; Richter, K The activity of protein phosphatase 5 towards native clients is modulated by the middle- and C-terminal domains of Hsp90.
Sci Rep. 2015; 5(4):17058-17058 Doi: 10.1038/srep17058 [OPEN ACCESS]
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** Hocking, HG; Häse, F; Madl, T; Zacharias, M; Rief, M; Žoldák, G A compact native 24-residue supersecondary structure derived from the villin headpiece subdomain.
Biophys J. 2015; 108(3):678-686 Doi: 10.1016/j.bpj.2014.11.3482 [OPEN ACCESS]
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** Kavšček, M; Bhutada, G; Madl, T; Natter, K Optimization of lipid production with a genome-scale model of Yarrowia lipolytica.
BMC Syst Biol. 2015; 9(2):72-72 Doi: 10.1186/s12918-015-0217-4 [OPEN ACCESS]
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** Meyer, NH; Mayerhofer, H; Tripsianes, K; Blindow, S; Barths, D; Mewes, A; Weimar, T; Köhli, T; Bade, S; Madl, T; Frey, A; Haas, H; Mueller-Dieckmann, J; Sattler, M; Schramm, G A Crystallin Fold in the Interleukin-4-inducing Principle of Schistosoma mansoni Eggs (IPSE/α-1) Mediates IgE Binding for Antigen-independent Basophil Activation.
J Biol Chem. 2015; 290(36): 22111-22126. Doi: 10.1074/jbc.M115.675066 [OPEN ACCESS]
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** Röhl, A; Tippel, F; Bender, E; Schmid, AB; Richter, K; Madl, T; Buchner, J Hop/Sti1 phosphorylation inhibits its co-chaperone function.
EMBO Rep. 2015; 16(2):240-249 Doi: 10.15252/embr.201439198 [OPEN ACCESS]
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** Röhl, A; Wengler, D; Madl, T; Lagleder, S; Tippel, F; Herrmann, M; Hendrix, J; Richter, K; Hack, G; Schmid, AB; Kessler, H; Lamb, DC; Buchner, J Hsp90 regulates the dynamics of its cochaperone Sti1 and the transfer of Hsp70 between modules.
Nat Commun. 2015; 6(6):6655-6655 Doi: 10.1038/ncomms7655 [OPEN ACCESS]
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** Sena, FV; Batista, AP; Catarino, T; Brito, JA; Archer, M; Viertler, M; Madl, T; Cabrita, EJ; Pereira, MM Type-II NADH:quinone oxidoreductase from Staphylococcus aureus has two distinct binding sites and is rate limited by quinone reduction.
Mol Microbiol. 2015; 98(2):272-288 Doi: 10.1111/mmi.13120 [OPEN ACCESS]
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2014

Originalarbeit (Zeitschrift)

** Huang, JR; Warner, LR; Sanchez, C; Gabel, F; Madl, T; Mackereth, CD; Sattler, M; Blackledge, M Transient electrostatic interactions dominate the conformational equilibrium sampled by multidomain splicing factor U2AF65: a combined NMR and SAXS study.
J Am Chem Soc. 2014; 136(19):7068-7076 Doi: 10.1021/ja502030n
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** Karagöz, GE; Duarte, AM; Akoury, E; Ippel, H; Biernat, J; Morán Luengo, T; Radli, M; Didenko, T; Nordhues, BA; Veprintsev, DB; Dickey, CA; Mandelkow, E; Zweckstetter, M; Boelens, R; Madl, T; Rüdiger, SG Hsp90-Tau complex reveals molecular basis for specificity in chaperone action.
Cell. 2014; 156(5): 963-974. Doi: 10.1016/j.cell.2014.01.037 [OPEN ACCESS]
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** Lorenz, OR; Freiburger, L; Rutz, DA; Krause, M; Zierer, BK; Alvira, S; Cuéllar, J; Valpuesta, JM; Madl, T; Sattler, M; Buchner, J Modulation of the Hsp90 chaperone cycle by a stringent client protein.
Mol Cell. 2014; 53(6): 941-953. Doi: 10.1016/j.molcel.2014.02.003 [OPEN ACCESS]
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** Neuhaus, A; Kooshapur, H; Wolf, J; Meyer, NH; Madl, T; Saidowsky, J; Hambruch, E; Lazam, A; Jung, M; Sattler, M; Schliebs, W; Erdmann, R A novel Pex14 protein-interacting site of human Pex5 is critical for matrix protein import into peroxisomes.
J Biol Chem. 2014; 289(1): 437-448. Doi: 10.1074/jbc.M113.499707 [OPEN ACCESS]
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Übersichtsarbeit

** Göbl, C; Madl, T; Simon, B; Sattler, M NMR approaches for structural analysis of multidomain proteins and complexes in solution.
Prog Nucl Magn Reson Spectrosc. 2014; 80(7):26-63 Doi: 10.1016/j.pnmrs.2014.05.003
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2013

Originalarbeit (Zeitschrift)

** Müller, R; Gräwert, MA; Kern, T; Madl, T; Peschek, J; Sattler, M; Groll, M; Buchner, J High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation.
Proc Natl Acad Sci U S A. 2013; 110(25): 10183-10188. Doi: 10.1073/pnas.1300547110 [OPEN ACCESS]
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** Putker, M; Madl, T; Vos, HR; de Ruiter, H; Visscher, M; van den Berg, MC; Kaplan, M; Korswagen, HC; Boelens, R; Vermeulen, M; Burgering, BM; Dansen, TB Redox-dependent control of FOXO/DAF-16 by transportin-1.
Mol Cell. 2013; 49(4): 730-742. Doi: 10.1016/j.molcel.2012.12.014 [OPEN ACCESS]
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** Zhang, Y; Madl, T; Bagdiul, I; Kern, T; Kang, HS; Zou, P; Mäusbacher, N; Sieber, SA; Krämer, A; Sattler, M Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition.
Nucleic Acids Res. 2013; 41(2): 1343-1354. Doi: 10.1093/nar/gks1097 [OPEN ACCESS]
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Übersichtsarbeit

** Hocking, HG; Zangger, K; Madl, T Studying the structure and dynamics of biomolecules by using soluble paramagnetic probes.
Chemphyschem. 2013; 14(13): 3082-3094. Doi: 10.1002/cphc.201300219 [OPEN ACCESS]
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2012

Originalarbeit (Zeitschrift)

** Dormann, D; Madl, T; Valori, CF; Bentmann, E; Tahirovic, S; Abou-Ajram, C; Kremmer, E; Ansorge, O; Mackenzie, IR; Neumann, M; Haass, C Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.
EMBO J. 2012; 31(22): 4258-4275. Doi: 10.1038/emboj.2012.261 [OPEN ACCESS]
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** Markley, JL; Akutsu, H; Asakura, T; Baldus, M; Boelens, R; Bonvin, A; Kaptein, R; Bax, A; Bezsonova, I; Gryk, MR; Hoch, JC; Korzhnev, DM; Maciejewski, MW; Case, D; Chazin, WJ; Cross, TA; Dames, S; Kessler, H; Lange, O; Madl, T; Reif, B; Sattler, M; Eliezer, D; Fersht, A; Forman-Kay, J; Kay, LE; Fraser, J; Gross, J; Kortemme, T; Sali, A; Fujiwara, T; Gardner, K; Luo, X; Rizo-Rey, J; Rosen, M; Gil, RR; Ho, C; Rule, G; Gronenborn, AM; Ishima, R; Klein-Seetharaman, J; Tang, P; van der Wel, P; Xu, Y; Grzesiek, S; Hiller, S; Seelig, J; Laue, ED; Mott, H; Nietlispach, D; Barsukov, I; Lian, LY; Middleton, D; Blumenschein, T; Moore, G; Campbell, I; Schnell, J; Vakonakis, IJ; Watts, A; Conte, MR; Mason, J; Pfuhl, M; Sanderson, MR; Craven, J; Williamson, M; Dominguez, C; Roberts, G; Günther, U; Overduin, M; Werner, J; Williamson, P; Blindauer, C; Crump, M; Driscoll, P; Frenkiel, T; Golovanov, A; Matthews, S; Parkinson, J; Uhrin, D; Williams, M; Neuhaus, D; Oschkinat, H; Ramos, A; Shaw, DE; Steinbeck, C; Vendruscolo, M; Vuister, GW; Walters, KJ; Weinstein, H; Wüthrich, K; Yokoyama, S In support of the BMRB.
Nat Struct Mol Biol. 2012; 19(9): 854-860. Doi: 10.1038/nsmb.2371
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** Tavanez, JP; Madl, T; Kooshapur, H; Sattler, M; Valcárcel, J hnRNP A1 proofreads 3' splice site recognition by U2AF.
Mol Cell. 2012; 45(3): 314-329. Doi: 10.1016/j.molcel.2011.11.033 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Dormann, D; Madl, T; Tahirovic, S; Bentmann, E; Abou-Ajram, C; Kremmer, E; Haass, C Arginine Methylation Modulates Transportin Binding and Nuclear Import of FUS
DEMENT GERIATR COGN. 2012; 33: 265-265.
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** Dormann, D; Madl, T; Tahirovic, S; Bentmann, E; Abou-Ajram, C; Kremmer, E; Haass, C Arginine Methylation Modulates Transportin Binding and Nuclear Import of FUS
DEMENT GERIATR COGN. 2012; 33: 19-19.
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2011

Originalarbeit (Zeitschrift)

** Mackereth, CD; Madl, T; Bonnal, S; Simon, B; Zanier, K; Gasch, A; Rybin, V; Valcárcel, J; Sattler, M Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF.
Nature. 2011; 475(7356): 408-411. Doi: 10.1038/nature10171 [OPEN ACCESS]
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** Madl, T; Gabel, F; Sattler, M NMR and small-angle scattering-based structural analysis of protein complexes in solution.
J Struct Biol. 2011; 173(3): 472-482. Doi: 10.1016/j.jsb.2010.11.004 [OPEN ACCESS]
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** Madl, T; Güttler, T; Görlich, D; Sattler, M Structural analysis of large protein complexes using solvent paramagnetic relaxation enhancements.
Angew Chem Int Ed Engl. 2011; 50(17): 3993-3997. Doi: 10.1002/anie.201007168
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** Tripsianes, K; Madl, T; Machyna, M; Fessas, D; Englbrecht, C; Fischer, U; Neugebauer, KM; Sattler, M Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins.
Nat Struct Mol Biol. 2011; 18(12): 1414-1420. Doi: 10.1038/nsmb.2185
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2010

Originalarbeit (Zeitschrift)

** Güttler, T; Madl, T; Neumann, P; Deichsel, D; Corsini, L; Monecke, T; Ficner, R; Sattler, M; Görlich, D NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat Struct Mol Biol. 2010; 17(11): 1367-1376. Doi: 10.1038/nsmb.1931 [OPEN ACCESS]
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** Madl, T; Felli, IC; Bertini, I; Sattler, M Structural analysis of protein interfaces from 13C direct-detected paramagnetic relaxation enhancements.
J Am Chem Soc. 2010; 132(21): 7285-7287. Doi: 10.1021/ja1014508
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** Meyer, NH; Tripsianes, K; Vincendeau, M; Madl, T; Kateb, F; Brack-Werner, R; Sattler, M Structural basis for homodimerization of the Src-associated during mitosis, 68-kDa protein (Sam68) Qua1 domain.
J Biol Chem. 2010; 285(37): 28893-28901. Doi: 10.1074/jbc.M110.126185 [OPEN ACCESS]
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** Simon, B; Madl, T; Mackereth, CD; Nilges, M; Sattler, M An efficient protocol for NMR-spectroscopy-based structure determination of protein complexes in solution.
Angew Chem Int Ed Engl. 2010; 49(11): 1967-1970. Doi: 10.1002/anie.200906147
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** Stefan, S; Belaj, F; Madl, T; Pietschnig, R A Radical Approach to Hydroxylaminotrichlorosilanes: Synthesis, Reactivity, and Crystal Structure of TEMPO-SiCl3 (TEMPO=2,2,6,6-Tetramethylpiperidine-N-oxyl)
EUR J INORG CHEM. 2010; (2): 289-297. Doi: 10.1002/ejic.200900969
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2009

Originalarbeit (Zeitschrift)

** Madl, T; Bermel, W; Zangger, K Use of relaxation enhancements in a paramagnetic environment for the structure determination of proteins using NMR spectroscopy.
Angew Chem Int Ed Engl. 2009; 48(44): 8259-8262. Doi: 10.1002/anie.200902561
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** Neufeld, C; Filipp, FV; Simon, B; Neuhaus, A; Schüller, N; David, C; Kooshapur, H; Madl, T; Erdmann, R; Schliebs, W; Wilmanns, M; Sattler, M Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.
EMBO J. 2009; 28(6): 745-754. Doi: 10.1038/emboj.2009.7 [OPEN ACCESS]
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** Zangger, K; Respondek, M; Göbl, C; Hohlweg, W; Rasmussen, K; Grampp, G; Madl, T Positioning of micelle-bound peptides by paramagnetic relaxation enhancements.
J Phys Chem B. 2009; 113(13): 4400-4406. Doi: 10.1021/jp808501x
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Originalarbeit (Konferenzband)

** Traar, P; Rumpler, A; Madl, T; Saischek, G; Francesconi, KA Synthesis of Naturally Occurring Arsenic-Containing Carbohydrates
AUST J CHEM. 2009; 62(6): 538-545. Doi: 10.1071/CH08461
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Kommentar

** Madl, T; Sattler, M Adhesion dance with raver.
Structure. 2009; 17(6): 781-783. Doi: 10.1016/j.str.2009.05.004
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2008

Originalarbeit (Zeitschrift)

** Spirk, S; Madl, T; Pietschnig, R Relax with TEMPO: A paramagnetic relaxation agent useful also for silicon-29 NMR spectroscopy
ORGANOMETALLICS. 2008; 27(4): 500-502. Doi: 10.1021/om701212j
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2007

Originalarbeit (Zeitschrift)

** Respondek, M; Madl, T; Göbl, C; Golser, R; Zangger, K Mapping the orientation of helices in micelle-bound peptides by paramagnetic relaxation waves.
J Am Chem Soc. 2007; 129(16): 5228-5234. Doi: 10.1021/ja069004f
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2006

Originalarbeit (Zeitschrift)

** Madl, T; Sterk, H; Mittelbach, M; Rechberger, GN Tandem mass spectrometric analysis of a complex triterpene saponin mixture of Chenopodium quinoa.
J Am Soc Mass Spectrom. 2006; 17(6): 795-806. Doi: 10.1016/j.jasms.2006.02.013 [OPEN ACCESS]
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** Madl, T; Van Melderen, L; Mine, N; Respondek, M; Oberer, M; Keller, W; Khatai, L; Zangger, K Structural basis for nucleic acid and toxin recognition of the bacterial antitoxin CcdA.
J Mol Biol. 2006; 364(2): 170-185. Doi: 10.1016/j.jmb.2006.08.082
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2005

Originalarbeit (Zeitschrift)

** Madl, T; Mittelbach, M Quantification of primary fatty acid amides in commercial tallow and tallow fatty acid methyl esters by HPLC-APCI-MS.
Analyst. 2005; 130(4): 565-570. Doi: 10.1039/b415779f
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