Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Egemnazarov Bakytbek |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2022
Abstract (Zeitschrift)
** Rittchen, S; Egemnazarov, B; Marsh, LM; Kuebler, WM; Sertic, M; Nigovic, B; Damico, R; Hassoun, PM; Crnkovic, S; Kwapiszewska, G
Galectin-3 drives a cycle of pro-inflammatory and -fibrotic right ventricular remodeling
WIEN KLIN WOCHENSCHR. 2022; 134(19-20): 725-725.
[Poster]
Web of Science
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2020
Originalarbeit (Zeitschrift)
** Veith, C; Neghabian, D; Luitel, H; Wilhelm, J; Egemnazarov, B; Muntanjohl, C; Fischer, JH; Dahal, BK; Schermuly, RT; Ghofrani, HA; Grimminger, F; Fink, L; Kwapiszewska, G; Weissmann, N; Sydykov, A
FHL-1 is not involved in pressure overload-induced maladaptive right ventricular remodeling and dysfunction.
Basic Res Cardiol. 2020; 115(2):17-17
Doi: 10.1007/s00395-019-0767-5
[OPEN ACCESS]
Web of Science
PubMed
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Kurzbericht/Letter
** Birnhuber, A; Egemnazarov, B; Biasin, V; Bonyadi Rad, E; Wygrecka, M; Olschewski, H; Kwapiszewska, G; Marsh, LM
CDK4/6 inhibition enhances pulmonary inflammatory infiltration in bleomycin-induced lung fibrosis.
Respir Res. 2020; 21(1):167-167
Doi: 10.1186/s12931-020-01433-w
[OPEN ACCESS]
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PubMed
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Übersichtsarbeit
** Weiss, A; Boehm, M; Egemnazarov, B; Grimminger, F; Pullamsetti, SS; Kwapiszewska, G; Schermuly, RT
Kinases as potential targets for treatment of pulmonary hypertension and right ventricular dysfunction.
Br J Pharmacol. 2019; 9(4):
Doi: 10.1111/bph.14919
[OPEN ACCESS]
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PubMed
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Abstract (Zeitschrift)
** Birnhuber, A; Egemnazarov, B; Biasin, V; Rad, EB; Olschewski, H; Kwapiszewska, G; Marsh, L
The CDK4/6 inhibitor, palbociclib intensifies pulmonary inflammation in bleomycin-induced lung fibrosis.
EUR RESPIR J. 2020; 56:
Doi: 10.1183/13993003.congress-2020.2285
[Poster]
Web of Science
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2019
Originalarbeit (Zeitschrift)
** Crnkovic, S; Egemnazarov, B; Damico, R; Marsh, LM; Nagy, BM; Douschan, P; Atsina, K; Kolb, TM; Mathai, SC; Hooper, JE; Ghanim, B; Klepetko, W; Fruhwald, F; Lassner, D; Olschewski, A; Olschewski, H; Hassoun, PM; Kwapiszewska, G
Disconnect between Fibrotic Response and Right Ventricular Dysfunction.
Am J Respir Crit Care Med. 2019; 199(12):1550-1560
Doi: 10.1164/rccm.201809-1737OC
[OPEN ACCESS]
Web of Science
PubMed
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** Egemnazarov, B; Kwapiszewska, G; Marsh, LM
Echocardiographic Measurement of Right Ventricular Diastolic Parameters in Mouse.
J Vis Exp. 2019; 10(146):
Doi: 10.3791/58021
Web of Science
PubMed
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** Papp, R; Nagaraj, C; Zabini, D; Nagy, BM; Lengyel, M; Skofic Maurer, D; Sharma, N; Egemnazarov, B; Kovacs, G; Kwapiszewska, G; Marsh, LM; Hrzenjak, A; Höfler, G; Didiasova, M; Wygrecka, M; Sievers, LK; Szucs, P; Enyedi, P; Ghanim, B; Klepetko, W; Olschewski, H; Olschewski, A
Targeting TMEM16A to reverse vasoconstriction and remodelling in idiopathic pulmonary arterial hypertension.
Eur Respir J. 2019; 53(6): 1800965
Doi: 10.1183/13993003.00965-2018
Web of Science
PubMed
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2018
Übersichtsarbeit
** Egemnazarov, B; Crnkovic, S; Nagy, BM; Olschewski, H; Kwapiszewska, G
Right ventricular fibrosis and dysfunction: Actual concepts and common misconceptions.
Matrix Biol. 2018; 68-69:507-521
Doi: 10.1016/j.matbio.2018.01.010
Web of Science
PubMed
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2017
Originalarbeit (Zeitschrift)
** Amirjanians, M; Egemnazarov, B; Sydykov, A; Kojonazarov, B; Brandes, R; Luitel, H; Pradhan, K; Stasch, JP; Redlich, G; Weissmann, N; Grimminger, F; Seeger, W; Ghofrani, H; Schermuly, R
Chronic intratracheal application of the soluble guanylyl cyclase stimulator BAY 41-8543 ameliorates experimental pulmonary hypertension.
Oncotarget. 2017; 8(18): 29613-29624.
Doi: 10.18632/oncotarget.16769
[OPEN ACCESS]
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** Nagy, BM; Nagaraj, C; Egemnazarov, B; Kwapiszewska, G; Stauber, RE; Avian, A; Olschewski, H; Olschewski, A
Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia.
Front Physiol. 2017; 8(8):98-98
Doi: 10.3389/fphys.2017.00098
[OPEN ACCESS]
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Abstract (Zeitschrift)
** Crnkovic, S; Egemnazarov, B; Marsh, L; Douschan, P; Ghanim, B; Klepetko, W; Fruhwald, F; Lassner, D; Olschewski, A; Olschewski, H; Kwapiszewska, G
Therapy of right ventricular fibrosis does not ameliorate right ventricular dysfunction
WIEN KLIN WOCHENSCHR. 2017; 129(19-20):756-756.
[Keynote lecture]
Web of Science
2016
Originalarbeit (Zeitschrift)
** Crnkovic, S; Schmidt, A; Egemnazarov, B; Wilhelm, J; Marsh, LM; Ghanim, B; Klepetko, W; Olschewski, A; Olschewski, H; Kwapiszewska, G
Functional and molecular factors associated with TAPSE in hypoxic pulmonary hypertension.
Am J Physiol Lung Cell Mol Physiol. 2016; 311(1):L59-L73
Doi: 10.1152/ajplung.00381.2015
[OPEN ACCESS]
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Abstract (Zeitschrift)
** Crnkovic, S; Jain, P; Egemnazarov, B; Marsh, LM; Ghanim, B; Klepetko, W; Holzer, P; Herzog, H; Olschewski, A; Kwapiszewska, G
Increased Expression Of Npy1r Mediated Increased Vascular Reactivity To Npy
AM J RESP CRIT CARE. .. 2016; 193: -International Conference of the American-Thoracic-Society (ATS); MAY 13-18, 2016; San Francisco, CA.
[Poster]
Web of Science
** Egemnazarov, BB; Crnkovic, S; Olschewski, H; Olschewski, A; Marsh, LM; Kwapiszewska, G
Cartilage oligomeric matrix protein (COMP) is a potential adaptive mechanism to the pressure overload in the right ventricle
EUR J HEART FAIL. 2016; 18: 149-149.
[Oral Communication]
Web of Science
** Nagy, BM; Nagaraj, C; Egemnazarov, B; Kwapiszewska, G; Stauber, R; Avian, A; Olschewski, A; Olschewski, H
Lack Of Abcg2 Leads To Biventricular Dysfunction And Remodelling In Response To Hypoxia
AM J RESP CRIT CARE. 2016; 193: -International Conference of the American-Thoracic-Society (ATS); MAY 13-18, 2016; San Francisco, CA.
[Poster]
Web of Science
2015
Originalarbeit (Zeitschrift)
** Egemnazarov, B; Schmidt, A; Crnkovic, S; Sydykov, A; Nagy, BM; Kovacs, G; Weissmann, N; Olschewski, H; Olschewski, A; Kwapiszewska, G; Marsh, LM
Pressure Overload Creates Right Ventricular Diastolic Dysfunction in a Mouse Model: Assessment by Echocardiography.
J Am Soc Echocardiogr. 2015; 28(7):828-843
Doi: 10.1016/j.echo.2015.02.014
Web of Science
PubMed
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Abstract (Zeitschrift)
** Crnkovic, S; Egemnazarov, B; Kovacs, G; Marsh, L; Ghanim, B; Klepetko, W; Olschewski, H; Olschewski, A; Kwapiszewska, G
Increased Galectin-3 Levels In Pulmonary Hypertension Mediate Right Ventricle Fibrotic Response
AM J RESP CRIT CARE. 2015; 191:
Web of Science
** Crnkovic, S; Jain, P; Egemnazarov, B; Marsh, LM; Ghanim, B; Klepetko, W; Holzer, P; Olschewski, A; Kwapiszewska, G
Increased expression of NPY1R mediates increased vascular reactivity to NPY
WIEN KLIN WOCHENSCHR. 2015; 127(19-20):818-818.
[Oral Communication]
Web of Science
** Egemnazarov, B; Crnkovic, S; Olschewski, H; Olschewski, A; Marsh, L; Kwapiszewska, G
The Role Of Cartilage Oligomeric Matrix Protein In Right Ventricular Fibrosis In The Pressure Overload Model Of Right Ventricular Dysfunction In Mice
AM J RESP CRIT CARE. 2015; 191: -International Conference of the American-Thoracic-Society (ATS); MAY 15-20, 2015; Denver, CO.
[Poster]
Web of Science
** Egemnazarov, B; Crnkovic, S; Olschewski, H; Olschewski, A; Marsh, LM; Kwapiszewska, G
Cartilage oligomeric matrix protein (COMP) as an adaptive mechanisms to the pressure overload in the right ventricle
WIEN KLIN WOCHENSCHR. 2015; 127(19-20):819-819.
[Oral Communication]
Web of Science
2014
Originalarbeit (Zeitschrift)
** Biasin, V; Marsh, LM; Egemnazarov, B; Wilhelm, J; Ghanim, B; Klepetko, W; Wygrecka, M; Olschewski, H; Eferl, R; Olschewski, A; Kwapiszewska, G
Meprin β, a novel mediator of vascular remodelling underlying pulmonary hypertension.
J Pathol. 2014; 233(1):7-17
Doi: 10.1002/path.4303
Web of Science
PubMed
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** Crnkovic, S; Egemnazarov, B; Jain, P; Seay, U; Gattinger, N; Marsh, LM; Bálint, Z; Kovacs, G; Ghanim, B; Klepetko, W; Schermuly, RT; Weissmann, N; Olschewski, A; Kwapiszewska, G
NPY/Y₁ receptor-mediated vasoconstrictory and proliferative effects in pulmonary hypertension.
Br J Pharmacol. 2014; 171(16):3895-3907
Doi: 10.1111/bph.12751
[OPEN ACCESS]
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PubMed
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** Schulz, R; Murzabekova, G; Egemnazarov, B; Kraut, S; Eisele, HJ; Dumitrascu, R; Heitmann, J; Seimetz, M; Witzenrath, M; Ghofrani, HA; Schermuly, RT; Grimminger, F; Seeger, W; Weissmann, N
Arterial hypertension in a murine model of sleep apnea: role of NADPH oxidase 2.
J Hypertens. 2014; 32(2):300-305
Doi: 10.1097/HJH.0000000000000016
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PubMed
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Abstract (Zeitschrift)
** Crnkovic, S; Egemnazarov, B; Seay, U; Gattinger, N; Jain, P; Marsh, LM; Balint, Z; Kovacs, G; Ghanim, B; Klepetko, W; Schermuly, RT; Weissmann, N; Olschewski, A; Kwapiszewska, G
Npy/npy1r Mediated Vasoconstrictory And Proliferative Effects In Pulmonary Hypertension
AM J RESP CRIT CARE. 2014; 189:
Web of Science
** Crnkovic, S; Schmidt, A; Egemnazarov, B; Marsh, LM; Olschewski, A; Olschewski, H; Kwapiszewska, G
Analysis Of Echocardiographic, Structural, Molecular And Functional Changes In The Hypoxia-Induced Cor Pulmonale
AM J RESP CRIT CARE. 2014; 189:
Web of Science
** Egemnazarov, B; Schmidt, A; Crnkovic, S; Nagy, BM; Sydykov, A; Kovacs, G; Olschewski, H; Olschewski, A; Kwapiszewska, G; Marsh, LM;
Pressure overload creates right ventricular diastolic dysfunction in a mouse model: assessment by echocardiography.
EUR J HEART FAIL. 2014; 16: 198-199.-???; ???; ???.
[Poster]
Web of Science
** Marsh, L; Jain, PP; Leber, R; Lehofer, B; Bloder, F; Nagaraj, C; Egemnazarov, B; Olschewski, A; Olschewski, H; Prassl, R
Development Of Inhalable Liposomal Formulations For The Treatment Of Pulmonary Hypertension
AM J RESP CRIT CARE. 2014; 189:
Web of Science
2013
Originalarbeit (Zeitschrift)
** Veit, F; Pak, O; Egemnazarov, B; Roth, M; Kosanovic, D; Seimetz, M; Sommer, N; Ghofrani, HA; Seeger, W; Grimminger, F; Brandes, RP; Schermuly, RT; Weissmann, N
Function of NADPH oxidase 1 in pulmonary arterial smooth muscle cells after monocrotaline-induced pulmonary vascular remodeling.
Antioxid Redox Signal. 2013; 19(18):2213-2231
Doi: 10.1089/ars.2012.4904
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Abstract (Zeitschrift)
** Biasin, V; Marsh, LM; Egemnazarov, B; Klepetko, W; Eferl, R; Olschewski, A; Kwapiszewska, G
Contribution Of Fra-2 Transcription Factor To Pulmonary Hypertension
AM J RESP CRIT CARE. 2013; 187:
Web of Science
** Crnkovic, S; Schmidt, A; Egemnazarov, B; Marsh, L; Olschewski, H; Olschewski, A; Olschewski, G; Kwapiszewska, G;
Right ventricular hypertrophy in hypoxia-exposed mice is fully compensated and has a distinct molecular expression profile.
WIEN KLIN WOCHENSCHR. 2013; 125(19-20):649-649.
[Poster]
Web of Science
** Veit, F; Pak, O; Egemnazarov, B; Roth, M; Kosanovic, D; Seimetz, M; Ghofrani, HA; Seeger, W; Grimminger, F; Brandes, R; Schermuly, RT; Weissmann, N
Nadph Oxidase 1 (nox1) In Non-Hypoxia Induced Pulmonary Hypertension
AM J RESP CRIT CARE. 2013; 187:
Web of Science
2012
Originalarbeit (Zeitschrift)
** Jayawardena, TM; Egemnazarov, B; Finch, EA; Zhang, L; Payne, JA; Pandya, K; Zhang, Z; Rosenberg, P; Mirotsou, M; Dzau, VJ
MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes.
Circ Res. 2012; 110(11):1465-1473
Doi: 10.1161/CIRCRESAHA.112.269035
[OPEN ACCESS]
Web of Science
PubMed
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** Ketabchi, F; Ghofrani, HA; Schermuly, RT; Seeger, W; Grimminger, F; Egemnazarov, B; Shid-Moosavi, SM; Dehghani, GA; Weissmann, N; Sommer, N
Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction.
Respir Res. 2012; 13(11):7-7
Doi: 10.1186/1465-9921-13-7
[OPEN ACCESS]
Web of Science
PubMed
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** Kwapiszewska, G; Chwalek, K; Marsh, LM; Wygrecka, M; Wilhelm, J; Best, J; Egemnazarov, B; Weisel, FC; Osswald, SL; Schermuly, RT; Olschewski, A; Seeger, W; Weissmann, N; Eickelberg, O; Fink, L
BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension.
Am J Pathol. 2012; 181(6):2018-2029
Doi: 10.1016/j.ajpath.2012.08.028
[OPEN ACCESS]
Web of Science
PubMed
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2011
Originalarbeit (Zeitschrift)
** Seimetz, M; Parajuli, N; Pichl, A; Veit, F; Kwapiszewska, G; Weisel, FC; Milger, K; Egemnazarov, B; Turowska, A; Fuchs, B; Nikam, S; Roth, M; Sydykov, A; Medebach, T; Klepetko, W; Jaksch, P; Dumitrascu, R; Garn, H; Voswinckel, R; Kostin, S; Seeger, W; Schermuly, RT; Grimminger, F; Ghofrani, HA; Weissmann, N
Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice.
Cell. 2011; 147(2): 293-305.
Doi: 10.1016/j.cell.2011.08.035
[OPEN ACCESS]
Web of Science
PubMed
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2010
Originalarbeit (Zeitschrift)
** Egemnazarov, B; Schermuly, RT; Dahal, BK; Elliott, GT; Hoglen, NC; Surber, MW; Weissmann, N; Grimminger, F; Seeger, W; Ghofrani, HA
Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction.
Respir Res. 2010; 11(11):81-81
Doi: 10.1186/1465-9921-11-81
[OPEN ACCESS]
Web of Science
PubMed
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Abstract (Zeitschrift)
** Egemnazarov, B; Amirjanians, V; Kojonazarov, B; Sydykov, A; Stasch, JP; Weissmann, N; Grimminger, F; Seeger, W; Schermuly, RT; Ghofrani, HA
Inhalative application of soluble guanylyl cyclase stimulator BAY 41-8543 for treatement of pulmonary arterial hypertension
AM J RESP CRIT CARE. 2010; 181:
Web of Science
** Ketabchi, F; Sommer, N; Egemnazarov, B; Ghofrani, HA; Schermuly, RT; Seeger, W; Grimminger, F; Shid-Moosavi, M; Dehghani, G; Weissmann, N
Effect of hypercapnia with and without acidosis on acute and sustained hypoxic pulmonary vasoconstriction
AM J RESP CRIT CARE. 2010; 181:
Web of Science
** Murzabekova, G; Eisele, H; Egemnazarov, B; Schermuly, RT; Ghofrani, H; Reichenberger, F; Mayer, K; Seeger, W; Grimminger, F; Weissmann, N; Schulz, R
Arterial Hypertension In A Murine Model Of Sleep Apnea - Role Of NADPH Oxidases
AM J RESP CRIT CARE. 2010; 181:
Web of Science
** Veit, F; Egemnazarov, B; Ghofrani, HA; Schermuly, RT; Seeger, W; Grimminger, F; Weissmann, N
Potential Role of NADPH Oxidase 1 Derived ROS in Vascular Remodeling in Monocrotaline-induced Pulmonary Arterial Hypertension of Rats
FREE RADICAL BIO MED. 2010; 49: S31-S31.
Doi: 10.1016/j.freeradbiomed.2010.10.056
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** Veit, F; Roth, M; Egemnazarov, B; Ghofrani, HA; Seeger, W; Schermuly, RT; Grimminger, F; Weissmann, N
Increased generation of reactive oxygen species in pulmonary arterial smooth muscle cells in monocrotaline-induced pulmonary arterial hypertension in rats
AM J RESP CRIT CARE. 2010; 181:
Web of Science
2009
Originalarbeit (Zeitschrift)
** Egemnazarov, B; Sydykov, A; Schermuly, RT; Weissmann, N; Stasch, JP; Sarybaev, AS; Seeger, W; Grimminger, F; Ghofrani, HA
Novel soluble guanylyl cyclase stimulator BAY 41-2272 attenuates ischemia-reperfusion-induced lung injury.
Am J Physiol Lung Cell Mol Physiol. 2009; 296(3):L462-L469
Doi: 10.1152/ajplung.90377.2008
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PubMed
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** Ketabchi, F; Egemnazarov, B; Schermuly, RT; Ghofrani, HA; Seeger, W; Grimminger, F; Shid-Moosavi, M; Dehghani, GA; Weissmann, N; Sommer, N
Effects of hypercapnia with and without acidosis on hypoxic pulmonary vasoconstriction.
Am J Physiol Lung Cell Mol Physiol. 2009; 297(5):L977-L983
Doi: 10.1152/ajplung.00074.2009
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PubMed
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Abstract (Zeitschrift)
** Egemnazarov, B; Sydykov, A; Pak, O; Schermuly, RT; Seeger, W; Grimminger, F; Weissmann, N; Ghofrani, A
Prevention of Lung Ischemia/Reperfusion Injury by nNos Inhibition-Involvement of Mitochondrial Transition Pores?
FREE RADICAL BIO MED. 2009; 47: S99-S99.
Web of Science
** Veit, F; Roth, M; Egemnazarov, B; Ghofrani, HA; Seeger, W; Schermully, RT; Grimminger, F; Weissmann, N
Increased Intracellular Generation of Reactive Oxygen Species in Pulmonary Arterial Smooth Muscle Cells from Monocrotaline-Treated Rats
FREE RADICAL BIO MED. 2009; 47: S104-S104.
Web of Science
2008
Abstract (Zeitschrift)
** Egemnazarov, B; Wehner, S; Hesslinger, C; Schermuly, RT; Ghofrani, HA; Seeger, W; Schudt, C; Grimminger, F; Weissmann, N
Endothelial Dysfunction Contributes to Vascular Tone Disturbances in Acute Lung Injury
FREE RADICAL BIO MED. 2008; 45: S44-S45.
Web of Science
** Fuchs, B; Bal, A; Egemnazarov, B; Roth, M; Sommer, N; Schermuly, RT; Ghofrani, HA; Seeger, W; Grimminger, F; Weissmann, N
Hypoxia-Dependent Superoxide Release in Pulmonary and Systemic Arterial Smooth Muscle Cells and Fibroblasts
FREE RADICAL BIO MED. 2008; 45: S46-S46.
Web of Science
2007
Abstract (Zeitschrift)
** Egemnazarov, B; Sydykov, A; Schermuly, RT; Voswinckel, R; Seeger, W; Grimminger, F; Weissmann, N; Ghofrani, A
Role of inducible NO synthase in ischemia/reperfusion injury of the lung
FREE RADICAL BIO MED. 2007; 43: S36-S37.
Web of Science
2006
Abstract (Zeitschrift)
** Egemnazarov, B; Sydykov, A; Schermuly, R; Weissmann, N; Seeger, W; Grimminger, E; Ghofrani, HA
Novel sGC activator BAY 412272 attenuates ischemia/reperfusion injury of the lung via inhibition of NADPH oxidase
MED KLIN. 2006; 101(4): A74-A74.
Web of Science
** Egemnazarov, B; Sydykov, A; Schermuly, R; Weissmann, W; Seeger, W; Grimminger, F; Ghofrani, HA
SGC stimulator BAY 582667 attenuates ischemia/reperfusion injury of the lung
MED KLIN. 2006; 101(4): A74-A74.
Web of Science
** Sydykov, A; Egemnazarov, B; Schermuly, R; Weissmann, N; Seeger, W; Grimminger, F; Ghofrani, HA
Importance of iNOS in the mediation of ischemia/reperfusion injury of the lung
MED KLIN. 2006; 101(4): A73-A74.
Web of Science
** Sydykov, A; Egemnazarov, B; Schermuly, R; Weissmann, N; Voswinckel, R; Seeger, W; Grimminger, F; Ghofrani, HA
Role of NADPH-oxidase in ischemia/reperfusion injury of the lung
MED KLIN. 2006; 101(4): A73-A73.
Web of Science