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Fickert Peter |

** = Publikationen gelistet in SCI/SSCI/Pubmed

2025

Originalarbeit (Zeitschrift)

** Prosenz, J; Grabherr, F; Semmler, G; Fickert, P; Hofer, H; Maieron, A; Zessner-Spitzenberg, J A national survey on gastroenterology and hepatology training reveals dissimilar perceptions between trainees and trainers and an important need for improvement in training programs.
Eur J Gastroenterol Hepatol. 2025; Doi: 10.1097/MEG.0000000000002929 [OPEN ACCESS]
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Übersichtsarbeit

** Ghallab, A; Mandorfer, M; Stirnimann, G; Geyer, J; Lindström, E; Luedde, T; van, der, Merwe, S; Rashidi-Alavijeh, J; Schmidt, H; Karpen, SJ; Fickert, P; Trauner, M; Hengstler, JG; Dawson, PA Enteronephrohepatic Circulation of Bile Acids and Therapeutic Potential of Systemic Bile Acid Transporter Inhibitors.
J Hepatol. 2025; Doi: 10.1016/j.jhep.2025.05.009
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2024

Originalarbeit (Zeitschrift)

** Liu, L; Zhou, S; Zaufel, A; Xie, Z; Racedo, S; Wagner, M; Zollner, G; Fickert, P; Zhang, Q Bile acids regulate SF-1 to alter cholesterol balance in adrenocortical cells via S1PR2.
Biochem Biophys Res Commun. 2024; 692:149342 Doi: 10.1016/j.bbrc.2023.149342
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** Zecher, BF; Ellinghaus, D; Schloer, S; Niehrs, A; Padoan, B; Baumdick, ME; Yuki, Y; Martin, MP; Glow, D; Schröder-Schwarz, J; Niersch, J; Brias, S; Müller, LM; Habermann, R; Kretschmer, P; Früh, T; Dänekas, J; Wehmeyer, MH; Poch, T; Sebode, M; Ellinghaus, E; Degenhardt, F; Körner, C; Hoelzemer, A; Fehse, B; Oldhafer, KJ; Schumacher, U; Sauter, G; Carrington, M; Franke, A; Bunders, MJ; Schramm, C; Altfeld, M, , International, PSC, Study, Group, (IPSCSG) HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells.
Gut. 2024; 73(2): 325-337. Doi: 10.1136/gutjnl-2023-329524 [OPEN ACCESS]
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Übersichtsarbeit

** Trauner, M; Halilbasic, E; Tatscher, E; Fickert, P [Primary sclerosing cholangitis-Diagnosis and treatment 2024].
INNERE MED. 2024; 65(4): 347-356. Doi: 10.1007/s00108-024-01697-0 [OPEN ACCESS]
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Editorial

** Fickert, P Detour of bile acid routes as therapeutic roadmap for cholemic nephropathy.
J Hepatol. 2024; 80(2):188-190 Doi: 10.1016/j.jhep.2023.11.008
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Biographical-Item

** Williamson, C; Bäckhed, F; Fickert, P In memoriam: Hanns-Ulrich Marschall (1954-2023).
J Hepatol. 2023; Doi: 10.1016/j.jhep.2023.09.040
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2023

Originalarbeit (Zeitschrift)

** Egger, M; Horvath, A; Prüller, F; Fickert, P; Finkelman, M; Kriegl, L; Grønbaek, H; Møller, HJ; Prattes, J; Krause, R; Hoenigl, M; Stadlbauer, V Fungal translocation measured by serum 1,3-ß-D-glucan correlates with severity and outcome of liver cirrhosis-A pilot study.
Liver Int. 2023; 43(9):1975-1983 Doi: 10.1111/liv.15648 [OPEN ACCESS]
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** Kendzia, S; Franke, S; Kröhler, T; Golob-Schwarzl, N; Schweiger, C; Toeglhofer, AM; Skofler, C; Uranitsch, S; El-Heliebi, A; Fuchs, J; Punschart, A; Stiegler, P; Keil, M; Hoffmann, J; Henderson, D; Lehrach, H; Yaspo, ML; Reinhard, C; Schäfer, R; Keilholz, U; Regenbrecht, C; Schicho, R; Fickert, P; Lax, SF; Erdmann, F; Schulz, MH; Kiemer, AK; Haybaeck, J; Kessler, SM A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer.
Mol Cancer. 2023; 22(1):89 Doi: 10.1186/s12943-023-01787-x [OPEN ACCESS]
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** Mandorfer, M; Aigner, E; Cejna, M; Ferlitsch, A; Datz, C; Gräter, T; Graziadei, I; Gschwantler, M; Hametner-Schreil, S; Hofer, H; Jachs, M; Loizides, A; Maieron, A; Peck-Radosavljevic, M; Rainer, F; Scheiner, B; Semmler, G; Reider, L; Reiter, S; Schoder, M; Schöfl, R; Schwabl, P; Stadlbauer, V; Stauber, R; Tatscher, E; Trauner, M; Ziachehabi, A; Zoller, H; Fickert, P; Reiberger, T Austrian consensus on the diagnosis and management of portal hypertension in advanced chronic liver disease (Billroth IV).
Wien Klin Wochenschr. 2023; 135(Suppl 3):493-523 Doi: 10.1007/s00508-023-02229-w [OPEN ACCESS]
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** Wagner-Skacel, J; Fink, N; Kahn, J; Dalkner, N; Jauk, E; Bengesser, S; Mairinger, M; Schüssler, G; Pieh, C; Stadlbauer, V; Kirsch, AH; Zitta, S; Rosenkranz, AR; Fickert, P; Schemmer, P Improving adherence to immunosuppression after liver or kidney transplantation in individuals with impairments in personality functioning - A randomized controlled single center feasibility study.
Front Psychol. 2023; 14:1150548 Doi: 10.3389/fpsyg.2023.1150548 [OPEN ACCESS]
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Kurzbericht/Letter

** Fickert, P; Lin, AC; Ritschl, H; Hammer, N; Denk, H Portal venous branches as an anatomic railroad for a gut-bile duct-axis.
J Hepatol. 2023; 79(2):e82-e84 Doi: 10.1016/j.jhep.2023.03.043
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Fallbericht

** Fabian, E; Reisinger, A; Ribitsch, W; Stadlbauer, V; Eherer, AJ; Roller-Wirnsberger, R; Toplak, H; Fickert, P; Krejs, GJ Clinical-Pathological Conference Series from the Medical University of Graz : Case No 175: A 54-year-old man with hyponatremia and delirium after surgery for a prolapsed disc.
Wien Klin Wochenschr. 2023; 135(7-8):203-209 Doi: 10.1007/s00508-022-02097-w (- Case Report) [OPEN ACCESS]
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Korrektur

** Golob-Schwarzl, N; Schweiger, C; Koller, C; Krassnig, S; Gogg-Kamerer, M; Gantenbein, N; Toeglhofer, AM; Wodlej, C; Bergler, H; Pertschy, B; Uranitsch, S; Holter, M; El-Heliebi, A; Fuchs, J; Punschart, A; Stiegler, P; Keil, M; Hoffmann, J; Henderson, D; Lehrach, H; Reinhard, C; Regenbrecht, C; Schicho, R; Fickert, P; Lax, S; Haybaeck, J Correction: Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.
Oncotarget. 2023; 14: 83-84. Doi: 10.18632/oncotarget.28115 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Trauner, M; Fickert, P; Trivedi, P; Denk, G; Färkkilä, M; Dill, M; Villadsen, GE; Berg, C; Jorgensen, KK; Vetter, M; Müller, T; Müllhaupt, B; Schramm, C; Strassburg, C; Bantel, H; Böttler, T; Beuers, U; Louvet, A; Halilbasic, E; Stiess, M; Proels, M; Manns, MP Norucholic acid for the treatment of primary sclerosing cholangitis: baseline data from a phase III trial
J HEPATOL. Abstracts. 2023; 78(S1):S403-S403.-EASL Congress 2023; JUN 21-24, 2023; Vienna, AUSTRIA. [Oral Communication]
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Biographical-Item

** Manns, MP; Wedemeyer, H; Fickert, P; Trauner, M Obituary for University Prof. Dr. med. Dr. h.c. mult. Peter Ferenci (1948-2023)
Z GASTROENTEROL. 2023; 61(08): 1135-1136.
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Kommentar

** Fickert, P Bacteria as key players in primary sclerosing cholangitis?
Gut. 2023; 72(4):607-608 Doi: 10.1136/gutjnl-2022-327876
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2022

Originalarbeit (Zeitschrift)

** Douschan, P; Kovacs, G; Sassmann, T; Stadlbauer, V; Avian, A; Foris, V; Tatscher, E; Durchschein, F; Rainer, F; Spindelboeck, W; Wagner, M; Kniepeiss, D; Zollner, G; Bachmaier, G; Fickert, P; Olschewski, H; Stauber, RE Pulmonary vascular disease and exercise hemodynamics in chronic liver disease.
Respir Med. 2022; 202:106987 Doi: 10.1016/j.rmed.2022.106987
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** Fandler-Höfler, S; Kneihsl, M; Stauber, RE; Bisping, E; Mangge, H; Wünsch, G; Haidegger, M; Fabisch, L; Hatab, I; Fickert, P; Werring, D; Enzinger, C; Gattringer, T Liver Fibrosis-4 index indicates atrial fibrillation in acute ischemic stroke.
Eur J Neurol. 2022; 29(8):2283-2288 Doi: 10.1111/ene.15377 [OPEN ACCESS]
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** Fürschuß, L; Rainer, F; Effenberger, M; Niederreiter, M; Portugaller, RH; Horvath, A; Fickert, P; Stadlbauer, V A novel score predicts mortality after transjugular intrahepatic portosystemic shunt: MOTS - Modified TIPS Score.
Liver Int. 2022; 42(8):1849-1860 Doi: 10.1111/liv.15236 [OPEN ACCESS]
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** Hartl, L; Tatscher, E; Weiss, M; Balcar, L; Strassl, R; Jachs, M; Mandorfer, M; Soliman, T; Stadlbauer, V; Schemmer, P; Berlakovich, G; Tilg, H; Schneeberger, S; Trauner, M; Fickert, P; Reiberger, T; Graziadei, I The impact of COVID-19 on liver transplantation programs in Austria.
Wien Klin Wochenschr. 2022; 134(23-24):875-882 Doi: 10.1007/s00508-022-02105-z [OPEN ACCESS]
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** Kniepeiss, D; Rosenkranz, AR; Fickert, P; Schemmer, P [Update: Immunosuppression in organ transplantation].
DEUT MED WOCHENSCHR. 2022; 147(18): 1199-1212. Doi: 10.1055/a-1716-8031
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Editorial

** Fickert, P; Rosenkranz, AR Bile Acids Are Important Contributors to AKI Associated with Liver Disease: PRO.
Kidney360. 2022; 3(1):17-20 Doi: 10.34067/KID.0005932020 [OPEN ACCESS]
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2021

Originalarbeit (Zeitschrift)

** Fandler-Höfler, S; Stauber, RE; Kneihsl, M; Wünsch, G; Haidegger, M; Poltrum, B; Pichler, A; Deutschmann, H; Enzinger, C; Fickert, P; Gattringer, T Non-invasive markers of liver fibrosis and outcome in large vessel occlusion stroke.
Ther Adv Neurol Disord. 2021; 14: 17562864211037239 Doi: 10.1177/17562864211037239 [OPEN ACCESS]
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** Reich, M; Spomer, L; Klindt, C; Fuchs, K; Stindt, J; Deutschmann, K; Höhne, J; Liaskou, E; Hov, JR; Karlsen, TH; Beuers, U; Verheij, J; Ferreira-Gonzalez, S; Hirschfield, G; Forbes, SJ; Schramm, C; Esposito, I; Nierhoff, D; Fickert, P; Fuchs, CD; Trauner, M; García-Beccaria, M; Gabernet, G; Nahnsen, S; Mallm, JP; Vogel, M; Schoonjans, K; Lautwein, T; Köhrer, K; Häussinger, D; Luedde, T; Heikenwalder, M; Keitel, V Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis.
J Hepatol. 2021; 75(3):634-646 Doi: 10.1016/j.jhep.2021.03.029
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** Sachdev, V; Duta-Mare, M; Korbelius, M; Vujić, N; Leopold, C; Freark, de, Boer, J; Rainer, S; Fickert, P; Kolb, D; Kuipers, F; Radovic, B; Gorkiewicz, G; Kratky, D Impaired Bile Acid Metabolism and Gut Dysbiosis in Mice Lacking Lysosomal Acid Lipase.
Cells. 2021; 10(10): Doi: 10.3390/cells10102619 [OPEN ACCESS]
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** Theiler-Schwetz, V; Schlager, H; Obermayer-Pietsch, B; Stojakovic, T; Fauler, G; Fickert, P; Zollner, G Hypercortisolism in patients with cholestasis is associated with disease severity.
BMC Gastroenterol. 2021; 21(1):460 Doi: 10.1186/s12876-021-02045-4 [OPEN ACCESS]
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** Zaufel, A; van, de, Wiel, SMW; Yin, L; Fauler, G; Chien, D; Dong, X; Gilmer, JF; Truong, JK; Dawson, PA; van, de, Graaf, SFJ; Fickert, P; Moustafa, T Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions.
BBA-MOL BASIS DIS. 2021; 1867(8): 166153 Doi: 10.1016/j.bbadis.2021.166153 [OPEN ACCESS]
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Übersichtsarbeit

** Panzitt, K; Fickert, P; Wagner, M Regulation of autophagy by bile acids and in cholestasis - CholestoPHAGY or CholeSTOPagy.
Biochim Biophys Acta Mol Basis Dis. 2021; 1867(2):166017-166017 Doi: 10.1016/j.bbadis.2020.166017
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Fallbericht

** Fabian, E; Kump, P; Schiller, D; Brcic, I; Gruber, C; Heitz, PU; Klöppel, G; Lipp, RW; Moinfar, F; Schöfl, R; Fickert, P; Krejs, GJ Clinical-Pathological Conference Series from the Medical University of Graz : Case No 173: A 77-year-old patient with adenocarcinoma of the prostate, liver metastases and watery diarrhea.
Wien Klin Wochenschr. 2021; 133(9-10):515-522 Doi: 10.1007/s00508-020-01791-x (- Case Report) [OPEN ACCESS]
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** Schreiber, N; Hackl, G; Reisinger, AC; Zollner-Schwetz, I; Eller, K; Schlagenhaufen, C; Pietzka, A; Czerwenka, C; Stark, TD; Kranzler, M; Fickert, P; Eller, P; Ehling-Schulz, M Acute Liver Failure after Ingestion of Fried Rice Balls: A Case Series of Bacillus cereus Food Poisonings.
Toxins (Basel). 2021; 14(1): Doi: 10.3390/toxins14010012 (- Case Report) [OPEN ACCESS]
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Abstract (Zeitschrift)

** Fandler-Hofler, S; Stauber, R; Kneihsl, M; Wunsch, G; Haidegger, M; Poltrum, B; Pichler, A; Deutschmann, H; Enzinger, C; Fickert, P; Gattringer, T Liver fibrosis is associated with atrial fibrillation and worse outcome in large vessel occlusion stroke
EUR J NEUROL. 2021; 28: 151-151.-7th Congress of the European Academy of Neurology; June 19-22, 2021; Vienna, Austria. [Oral Communication]
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2020

Originalarbeit (Zeitschrift)

** Baghdasaryan, A; Ofner-Ziegenfuß, L; Lackner, C; Fickert, P; Resch, B; Morris, NM; Deutschmann, A Histological demonstration of BSEP/ABCB11 inhibition in transient neonatal cholestasis: a case report.
BMC Pediatr. 2020; 20(1):340-340 Doi: 10.1186/s12887-020-02201-x (- Case Report) [OPEN ACCESS]
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** Blesl, A; Jüngst, C; Lammert, F; Fauler, G; Rainer, F; Leber, B; Feldbacher, N; Stromberger, S; Wildburger, R; Spindelböck, W; Fickert, P; Horvath, A; Stadlbauer, V Secondary Sclerosing Cholangitis in Critically Ill Patients Alters the Gut-Liver Axis: A Case Control Study.
Nutrients. 2020; 12(9): Doi: 10.3390/nu12092728 [OPEN ACCESS]
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** Fabian, E; Gröchenig, HP; Bauer, PK; Eherer, AJ; Gugatschka, M; Binder, L; Langner, C; Fickert, P; Krejs, GJ Clinical-Pathological Conference Series from the Medical University of Graz : Case No 171: A 37-year-old engineer with bolus hold-up (esophageal food impaction).
Wien Klin Wochenschr. 2020; 132(17-18):551-559 Doi: 10.1007/s00508-020-01694-x [OPEN ACCESS]
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** Horvath, A; Durdevic, M; Leber, B; di Vora, K; Rainer, F; Krones, E; Douschan, P; Spindelboeck, W; Durchschein, F; Zollner, G; Stauber, RE; Fickert, P; Stiegler, P; Stadlbauer, V Changes in the Intestinal Microbiome during a Multispecies Probiotic Intervention in Compensated Cirrhosis.
Nutrients. 2020; 12(6): Doi: 10.3390/nu12061874 [OPEN ACCESS]
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** Kniepeiss, D; Rosenkranz, AR; Fickert, P; Schemmer, P Update: Immunosuppression for Organ Transplant Patients.
TRANSFUSIONSMEDIZIN. 2020; 10(04): 221-233. Doi: 10.1055/a-1238-3285
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** Panzitt, K; Jungwirth, E; Krones, E; Lee, JM; Pollheimer, M; Thallinger, GG; Kolb-Lenz, D; Xiao, R; Thorell, A; Trauner, M; Fickert, P; Marschall, HU; Moore, DD; Wagner, M FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
J Hepatol. 2020; 72(6):1122-1131 Doi: 10.1016/j.jhep.2020.01.014 [OPEN ACCESS]
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Übersichtsarbeit

** Fickert, P; Rosenkranz, AR Cholemic Nephropathy Reloaded.
Semin Liver Dis. 2020; 40(1):91-100 Doi: 10.1055/s-0039-1698826 [OPEN ACCESS]
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** Wagner, M; Fickert, P Drug Therapies for Chronic Cholestatic Liver Diseases.
Annu Rev Pharmacol Toxicol. 2020; 60(1):503-527 Doi: 10.1146/annurev-pharmtox-010818-021059
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Abstract (Zeitschrift)

** Furschuss, L; Rainer, F; Effenberger, M; Niederreiter, M; Portugaller, RH; Fickert, P; Stadlbauer, V The modified TIPS-Score (MOTS) improves the Assessment of the Mortality Risk after transjugular intrahepatic portosystemic Shunt (TIPS) and thus the Patient Selection.
WIEN KLIN WOCHENSCHR. 2020; 132(SUPPL 2):76-77.London, online. [Poster]
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2019

Originalarbeit (Zeitschrift)

** Al-Dury, S; Wahlström, A; Panzitt, K; Thorell, A; Ståhlman, M; Trauner, M; Fickert, P; Bäckhed, F; Fändriks, L; Wagner, M; Marschall, HU Obeticholic acid may increase the risk of gallstone formation in susceptible patients.
J Hepatol. 2019; 71(5):986-991 Doi: 10.1016/j.jhep.2019.06.011
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** Grabner, GF; Fawzy, N; Pribasnig, MA; Trieb, M; Taschler, U; Holzer, M; Schweiger, M; Wolinski, H; Kolb, D; Horvath, A; Breinbauer, R; Rülicke, T; Rabl, R; Lass, A; Stadlbauer, V; Hutter-Paier, B; Stauber, RE; Fickert, P; Zechner, R; Marsche, G; Eichmann, TO; Zimmermann, R Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans.
J Lipid Res. 2019; 60(5):1020-1031 Doi: 10.1194/jlr.M093351 [OPEN ACCESS]
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** Horvath, A; Rainer, F; Bashir, M; Leber, B; Schmerboeck, B; Klymiuk, I; Groselj-Strele, A; Durdevic, M; Freedberg, DE; Abrams, JA; Fickert, P; Stiegler, P; Stadlbauer, V Biomarkers for oralization during long-term proton pump inhibitor therapy predict survival in cirrhosis.
Sci Rep. 2019; 9(1):12000-12000 Doi: 10.1038/s41598-019-48352-5 [OPEN ACCESS]
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** Kleinegger, F; Hofer, E; Wodlej, C; Golob-Schwarzl, N; Birkl-Toeglhofer, AM; Stallinger, A; Petzold, J; Orlova, A; Krassnig, S; Reihs, R; Niedrist, T; Mangge, H; Park, YN; Thalhammer, M; Aigelsreiter, A; Lax, S; Garbers, C; Fickert, P; Rose-John, S; Moriggl, R; Rinner, B; Haybaeck, J Pharmacologic IL-6Rα inhibition in cholangiocarcinoma promotes cancer cell growth and survival.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(2):308-321 Doi: 10.1016/j.bbadis.2018.11.006 [OPEN ACCESS]
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** Liu, L; Panzitt, K; Racedo, S; Wagner, M; Platzer, W; Zaufel, A; Theiler-Schwetz, V; Obermayer-Pietsch, B; Müller, H; Höfler, G; Heinemann, A; Zollner, G; Fickert, P Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1PR2, ERK and SF-1.
Liver Int. 2019; 39(11):2112-2123 Doi: 10.1111/liv.14052 [OPEN ACCESS]
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** Traussnigg, S; Schattenberg, JM; Demir, M; Wiegand, J; Geier, A; Teuber, G; Hofmann, WP; Kremer, AE; Spreda, F; Kluwe, J; Petersen, J; Boettler, T; Rainer, F; Halilbasic, E; Greinwald, R; Pröls, M; Manns, MP; Fickert, P; Trauner, M; Austrian/German NAFLD-norUDCA study group Norursodeoxycholic acid versus placebo in the treatment of non-alcoholic fatty liver disease: a double-blind, randomised, placebo-controlled, phase 2 dose-finding trial.
Lancet Gastroenterol Hepatol. 2019; 4(10):781-793 Doi: 10.1016/S2468-1253(19)30184-0
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Übersichtsarbeit

** Theiler-Schwetz, V; Zaufel, A; Schlager, H; Obermayer-Pietsch, B; Fickert, P; Zollner, G Bile acids and glucocorticoid metabolism in health and disease.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(1):243-251 Doi: 10.1016/j.bbadis.2018.08.001 [OPEN ACCESS]
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Editorial

** Fickert, P Is This the Last Requiem for Simtuzumab?
Hepatology. 2019; 69(2):476-479 Doi: 10.1002/hep.30309 [OPEN ACCESS]
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** Fickert, P; Wagner, M Preface - Animal models in liver disease.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(5):867-868 Doi: 10.1016/j.bbadis.2019.02.004 [OPEN ACCESS]
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Fallbericht

** Blesl, A; Brcic, I; Jaschke, W; Öfner, D; Fickert, P; Plank, J Chronic gastric ulcer disease complicating selective internal radiation therapy (SIRT) in a patient with cholangiocellular carcinoma.
Z Gastroenterol. 2019; 57(11):1304-1308 Doi: 10.1055/a-1016-3698 (- Case Report)
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** Rainer, F; Blesl, A; Spindelboeck, W; Schemmer, P; Fickert, P; Schreiber, F A novel way to avoid reoperation for biliary strictures after liver transplantation: cholangioscopy-assisted guidewire placement.
Endoscopy. 2019; 51(11):E314-E316 Doi: 10.1055/a-0896-2360 (- Case Report) [OPEN ACCESS]
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** Rainer, F; Prenner, G; Binder, LP; Fickert, P; Plank, J Case of nasogastric tube dysfunction.
Gut. 2019; 68(2):206-262 Doi: 10.1136/gutjnl-2017-315619 (- Case Report)
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Korrektur

** Stadlbauer, V; Horvath, A; Ribitsch, W; Schmerböck, B; Schilcher, G; Lemesch, S; Stiegler, P; Rosenkranz, AR; Fickert, P; Leber, B Author Correction: Structural and functional differences in gut microbiome composition in patients undergoing haemodialysis or peritoneal dialysis.
Sci Rep. 2019; 9(1):8522-8522 Doi: 10.1038/s41598-019-43263-x [OPEN ACCESS]
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Abstract (Zeitschrift)

** Horvath, A; Durdevic, M; Leber, B; di Vora, K; Rainer, F; Douschan, P; Krones, E; Spindelboeck, W; Durchschein, F; Zollner, G; Stauber, R; Fickert, P; Stiegler, P; Stadlbauer, V Changes in the intestinal microbiome during probiotic intervention in cirrhosis
J HEPATOL. 2019; 70: E648-E648.-International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 10-14, 2019; Vienna, AUSTRIA. Doi: 10.1016/S0618-8278(19)31290-3 [Poster]
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** Kniepeiss, D; Janout, S; Schrem, H; Mathe, Z; Bachmaier, G; Lackner, C; Fickert, P; Toller, W; Muller, H; Schemmer, P EXCELLENT OUTCOME QUALITY IS NOT DEPENDENT ON A HIGH CASELOAD IN LIVER TRANSPLANTATION
TRANSPL INT. 2019; 32: 30-30.-28. Jahrestagung der Deutschen Transplantationsgesellschaft, 17. – 19.10.2019, Hannover; 17. – 19.10.2019; Hannover, Deutschland. [Poster]
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** Kowdley, KV; Minuk, GY; Pagadala, MR; Gulamhusein, A; Swain, MG; Neff, GW; Zogg, D; Bowlus, CL; Agarwal, K; Yoshida, EM; Li, Y; Li, G; Chung, CH; Subramanian, M; Myers, RP; Sheikh, AM; Shiffman, ML; Fickert, P THE NONSTEROIDAL FARNESOID X RECEPTOR (FXR) AGONIST CILOFEXOR IMPROVES LIVER BIOCHEMISTRY IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS (PBC): A PHASE 2, RANDOMIZED, PLACEBO-CONTROLLED TRIAL
HEPATOLOGY. 2019; 70: 31A-32A.-Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting; NOV 08-12, 2019; Boston, MA. [Poster]
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** Schwetz, V; Schlager, H; Obermayer-Pietsch, B; Stojakovic, T; Fauler, G; Fickert, P; Zollner, G Alteration of glucocorticoid metabolism in patients with cholestasis
J HEPATOL. 2019; 70: E417-E418.-International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 10-14, 2019; Vienna, AUSTRIA. Doi: 10.1016/S0618-8278(19)30822-9 [Poster]
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** Tewes, B; Trauner, MH; Steinacher, D; Fickert, P; Stiess, M; Zimmermann, T; Greinwald, R NORURSODEOXYCHOLIC ACID (NORUDCA) SIGNIFICANTLY AMELIORATES LIVER INJURY IN THE STAM MOUSE MODEL FOR NON-ALCOHOLIC STEATOHEPATITIS (NASH)
HEPATOLOGY. 2019; 70: 1298A-1299A.-Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting; NOV 08-12, 2019; Boston, MA. [Oral Communication]
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Kommentar

** Fickert, P; Marschall, HU Gut pathobionts as triggers for liver diseases.
Nat Microbiol. 2019; 4(3):380-381 Doi: 10.1038/s41564-019-0388-7
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2018

Originalarbeit (Zeitschrift)

** Durchschein, F; Krones, E; Pollheimer, MJ; Zollner, G; Wagner, M; Raufman, JP; Fickert, P Genetic loss of the muscarinic M₃ receptor markedly alters bile formation and cholestatic liver injury in mice.
Hepatol Res. 2018; 48(3):E68-E77 Doi: 10.1111/hepr.12928 [OPEN ACCESS]
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** Pollheimer, MJ; Racedo, S; Mikels-Vigdal, A; Marshall, D; Bowlus, C; Lackner, C; Madl, T; Karlsen, TH; Hov, JR; Lyman, SK; Adamkewicz, J; Smith, V; Moreau, E; Zollner, G; Eide, TJ; Stojakovic, T; Scharnagl, H; Gruber, HJ; Stauber, RE; Trauner, M; Fickert, P Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis.
J Hepatol. 2018; 69(2):368-377 Doi: 10.1016/j.jhep.2018.04.009
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** Rainer, F; Horvath, A; Sandahl, TD; Leber, B; Schmerboeck, B; Blesl, A; Groselj-Strele, A; Stauber, RE; Fickert, P; Stiegler, P; Møller, HJ; Grønbaek, H; Stadlbauer, V Soluble CD163 and soluble mannose receptor predict survival and decompensation in patients with liver cirrhosis, and correlate with gut permeability and bacterial translocation.
Aliment Pharmacol Ther. 2018; 47(5):657-664 Doi: 10.1111/apt.14474 [OPEN ACCESS]
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** Robin, MJD; Appelman, MD; Vos, HR; van Es, RM; Paton, JC; Paton, AW; Burgering, B; Fickert, P; Heijmans, J; van de Graaf, SFJ Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na⁺-Taurocholate Cotransporting Polypeptide.
Hepatol Commun. 2018; 2(12):1550-1566 Doi: 10.1002/hep4.1262 [OPEN ACCESS]
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** Tang, Y; Blomenkamp, KS; Fickert, P; Trauner, M; Teckman, JH NorUDCA promotes degradation of α1-antitrypsin mutant Z protein by inducing autophagy through AMPK/ULK1 pathway.
PLoS One. 2018; 13(8):e0200897-e0200897 Doi: 10.1371/journal.pone.0200897 [OPEN ACCESS]
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Übersichtsarbeit

** Haberl, J; Zollner, G; Fickert, P; Stadlbauer, V To salt or not to salt?-That is the question in cirrhosis.
Liver Int. 2018; 38(7):1148-1159 Doi: 10.1111/liv.13750 [OPEN ACCESS]
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** Krones, E; Pollheimer, MJ; Rosenkranz, AR; Fickert, P Cholemic nephropathy - Historical notes and novel perspectives.
Biochim Biophys Acta Mol Basis Dis. 2018; 1864(4 Pt B):1356-1366 Doi: 10.1016/j.bbadis.2017.08.028 [OPEN ACCESS]
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Fallbericht

** Fabian, E; Peck-Radosavljevic, M; Krones, E; Mueller, H; Lackner, C; Spreizer, C; Putz-Bankuti, C; Fuerst, W; Wutte, N; Fickert, P; Mischinger, H; Krejs, GJ Clinical-Pathological Conference Series from the Medical University of Graz : Case No 161: A 42-year-old journalist with fatigue, elevated liver function tests, hyperglycemia and pruritus.
Wien Klin Wochenschr. 2018; 130(17-18):545-556 Doi: 10.1007/s00508-018-1379-z (- Case Report) [OPEN ACCESS]
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Abstract (Zeitschrift)

** Al-Dury, S; Wahlstrom, A; Katrin, P; Anders, T; Stahlman, M; Olsson, L; Trauner, M; Fickert, P; Moore, D; Backhed, F; Fandriks, L; Wagner, M; Marschall, HU FXR agonist obeticholic acid increases gallbladder FGF19 in gallstone patients
J HEPATOL. 2018; 68: S449-S449.-International Liver Congress (ILC); APR 11-15, 2018; Paris, FRANCE. Doi: 10.1016/S0168-8278(18)31140-1 [Oral Communication]
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** Al-Dury, S; Wahlstrom, A; Panzitt, K; Thorell, A; Stahlman, M; Trauner, MH; Fickert, P; Backhed, F; Fandriks, L; Wagner, M; Marschall, HU Obeticholic Acid Increases Cholesterol Saturation and FGF19 in Human Gallbladder Bile
HEPATOLOGY. 2018; 68: 159A-159A.-Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting; NOV 09-13, 2018; San Francisco, CA. [Oral Communication]
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** Pollheimer, M; Racedo, S; Mikels-Vigdal, A; Bowlus, C; Lackner, C; Karlsen, TH; Hov, JR; Lyman, SK; Adamkewicz, J; Smith, V; Moreau, E; Eide, TJ; Stojakovic, T; Stauber, RE; Trauner, M; Fickert, P Lysyl oxidase-like protein 2 in cholangiopathies
VIRCHOWS ARCH. 2018; 473: S6-S7.-30th European Congress of Pathology; 08-12.09, 2018 ; Bilbao. [Oral Communication]
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** Rainer, F; Horvath, A; Bashir, M; Leber, B; Schmerboeck, B; Blesl, A; Madl, T; Klymiuk, I; Groselj-Strele, A; Durdevic, M; Gronbaek, H; Moller, HJ; Freedber, DE; Abrams, JA; Stauber, RE; Fickert, P; Stiegler, P; Stadlbauer, V Loss of colonization resistance in cirrhosis facilitates proton pump inhibitor-associated oralization of the colonic microbiome
J HEPATOL. 2018; 68: S700-S700.-International Liver Congress (ILC); APR 11-15, 2018; Paris, FRANCE. Doi: 10.1016/S0168-8278(18)31663-5 [Poster]
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** Sassmann, T; Kovacs, G; Stauber, R; Foris, V; Pfeiffer, S; Gruber, F; Revelant, F; Stadlbauer, V; Kniepeiss, D; Zollner, G; Fickert, P; Avian, A; Olschewski, A; Olschewski, H; Douschan, P Diastolic dysfunction and cardiopulmonary exercise capacity in patients with advanced liver disease-results from a prospective cross-sectional cohort
WIEN KLIN WOCHENSCHR. 2018; 130(19-20):627-627.-ÖGP Jahrestagung; OKT 18-20, 2018; Linz, Austria. [Poster]
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** Sassmann, T; Kovacs, G; Stauber, RE; Revelant, F; Foris, V; Pfeiffer, S; Gruber, F; Stadlbauer, V; Kniepeiss, D; Zollner, G; Fickert, P; Avian, A; Olschewski, A; Olschewski, H; Douschan, P; Impact of diastolic dysfunction on exercise capacity in patients with liver cirrhosis
European Respiratory Journal. 2018; 52(sup 62):-ERS International Congress; SEP 15 - 19, 2018; Paris, France. Doi: 10.1183/13993003.congress-2018.PA2486 [Poster]
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Kommentar

** Wagner, M; Fickert, P Time for the dawn of multimodal therapies and the dusk for mono-therapeutic trials for cholestatic liver diseases?
Liver Int. 2018; 38(6):991-994 Doi: 10.1111/liv.13744 [OPEN ACCESS]
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2017

Originalarbeit (Zeitschrift)

** Aabakken, L; Karlsen, TH; Albert, J; Arvanitakis, M; Chazouilleres, O; Dumonceau, JM; Färkkilä, M; Fickert, P; Hirschfield, GM; Laghi, A; Marzioni, M; Fernandez, M; Pereira, SP; Pohl, J; Poley, JW; Ponsioen, CY; Schramm, C; Swahn, F; Tringali, A; Hassan, C Role of endoscopy in primary sclerosing cholangitis: European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL) Clinical Guideline.
Endoscopy. 2017; 49(6):588-608 Doi: 10.1055/s-0043-107029 [OPEN ACCESS]
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** Fickert, P; Hirschfield, GM; Denk, G; Marschall, HU; Altorjay, I; Färkkilä, M; Schramm, C; Spengler, U; Chapman, R; Bergquist, A; Schrumpf, E; Nevens, F; Trivedi, P; Reiter, FP; Tornai, I; Halilbasic, E; Greinwald, R; Pröls, M; Manns, MP; Trauner, M; European PSC norUDCA Study Group norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis.
J Hepatol. 2017; 67(3):549-558 Doi: 10.1016/j.jhep.2017.05.009 [OPEN ACCESS]
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** Golob-Schwarzl, N; Krassnig, S; Toeglhofer, AM; Park, YN; Gogg-Kamerer, M; Vierlinger, K; Schröder, F; Rhee, H; Schicho, R; Fickert, P; Haybaeck, J New liver cancer biomarkers: PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors.
Eur J Cancer. 2017; 83(60):56-70 Doi: 10.1016/j.ejca.2017.06.003
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** Golob-Schwarzl, N; Schweiger, C; Koller, C; Krassnig, S; Gogg-Kamerer, M; Gantenbein, N; Toeglhofer, AM; Wodlej, C; Bergler, H; Pertschy, B; Uranitsch, S; Holter, M; El-Heliebi, A; Fuchs, J; Punschart, A; Stiegler, P; Keil, M; Hoffmann, J; Henderson, D; Lehrach, H; Reinhard, C; Regenbrecht, C; Schicho, R; Fickert, P; Lax, S; Haybaeck, J Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.
Oncotarget. 2017; 8(60):101224-101243 Doi: 10.18632/oncotarget.20642 [OPEN ACCESS]
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** Jüngst, C; Stadlbauer, V; Reichert, MC; Zimmer, V; Weber, SN; Ofner-Ziegenfuß, L; Voigtländer, T; Spindelböck, W; Fickert, P; Kirchner, GI; Lammert, F; Lankisch, TO; Krawczyk, M NOD2 gene variants confer risk for secondary sclerosing cholangitis in critically ill patients.
Sci Rep. 2017; 7(1):7026-7026 Doi: 10.1038/s41598-017-06268-y [OPEN ACCESS]
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** Krones, E; Eller, K; Pollheimer, MJ; Racedo, S; Kirsch, AH; Frauscher, B; Wahlström, A; Ståhlman, M; Trauner, M; Grahammer, F; Huber, TB; Wagner, K; Rosenkranz, AR; Marschall, HU; Fickert, P NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice.
J Hepatol. 2017; 67(1):110-119 Doi: 10.1016/j.jhep.2017.02.019
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** Reiberger, T; Püspök, A; Schoder, M; Baumann-Durchschein, F; Bucsics, T; Datz, C; Dolak, W; Ferlitsch, A; Finkenstedt, A; Graziadei, I; Hametner, S; Karnel, F; Krones, E; Maieron, A; Mandorfer, M; Peck-Radosavljevic, M; Rainer, F; Schwabl, P; Stadlbauer, V; Stauber, R; Tilg, H; Trauner, M; Zoller, H; Schöfl, R; Fickert, P Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
Wien Klin Wochenschr. 2017; 129(Suppl 3): 135-158. Doi: 10.1007/s00508-017-1262-3 [OPEN ACCESS]
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** Stadlbauer, V; Horvath, A; Ribitsch, W; Schmerböck, B; Schilcher, G; Lemesch, S; Stiegler, P; Rosenkranz, AR; Fickert, P; Leber, B Structural and functional differences in gut microbiome composition in patients undergoing haemodialysis or peritoneal dialysis.
Sci Rep. 2017; 7(1):15601-15601 Doi: 10.1038/s41598-017-15650-9 [OPEN ACCESS]
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Kurzbericht/Letter

** Schaffellner, S; Stadlbauer, V; Sereinigg, M; Mìller, H; Högenauer, C; Fickert, P; Krumnikl, J; Lackner, C; Kniepeiss, D; Stauber, RE Niacin-Associated Acute Hepatotoxicity Leading to Emergency Liver Transplantation.
Am J Gastroenterol. 2017; 112(8): 1345-1346. Doi: 10.1038/ajg.2017.171 (- Case Report)
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** Stampfer, L; Sperl, D; Fickert, P; Lackner, H; Sovinz, P; Ofner-Ziegenfuß, L; Strenger, V; Urban, C; Jahnel, J; Seidel, MG Life-threatening sinusoidal obstruction syndrome after high-dose chemotherapy linked to compound heterozygous mutations in ABCB11.
Pediatr Blood Cancer. 2017; 64(12): Doi: 10.1002/pbc.26666
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Übersichtsarbeit

** Fickert, P; Wagner, M Biliary bile acids in hepatobiliary injury - What is the link?
J Hepatol. 2017; 67(3):619-631 Doi: 10.1016/j.jhep.2017.04.026 [OPEN ACCESS]
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Editorial

** Fickert, P Bad memories from the gut may cause nightmares for the bile ducts.
J Hepatol. 2017; 66(1):5-7 Doi: 10.1016/j.jhep.2016.09.016 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Blesl, A; Horvath, A; Jungst, C; Leber, B; Schmerboeck, B; Tawdrous, M; Stiegler, P; Rainer, F; Spindelboeck, W; Fickert, P; Lammert, F; Reichert, M; Stadlbauer, V. Dysbiosis of the gut microbiota and increased gut permeability characterize secondary sclerosing cholangitis in critically ill patients (SSC-CIP)
J HEPATOL. 2017; 66(1):S354-S355.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)31046-2 [Poster]
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** Douschan, P; Kovacs, G; Stadlbauer, V; Kniepeiss, D; Krones, E; Durchschein, F; Rainer, F; Spindelboeck, W; Wagner, M; Zollner, G; Avian, A; Fickert, P; Olschewski, A; Olschewski, H; Stauber, RE Exercise capacity and exercise hemodynamics in the screening for pulmonary vascular disease (PVD) in patients with portal hypertension - results from a prospective cross-sectional study
J HEPATOL. 2017; 66(1):S568-S569.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)31556-8 [Poster]
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** Douschan, P; Kovacs, G; Stauber, R; Foris, V; Pfeiffer, S; Gruber, F; Sassmann, T; Revelant, F; Stadlbauer, V; Kniepeiss, D; Fickert, P; Avian, A; Olschewski, A; Olschewski, H Impact of chronic liver disease on pulmonary hemodynamics and exercise tolerance - results from a prospective cross-sectional study
WIEN KLIN WOCHENSCHR. 2017; 129(19-20):768-769. [Poster]
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** Douschan, P; Kovacs, G; Stauber, R; Foris, V; Pfeiffer, S; Gruber, F; Stadlbauer-Kollner, V; Kniepeiss, D; Zollner, G; Fickert, P; Avian, A; Olschewski, A; Olschewski, H Exercise Hemodynamics In The Screening For Pulmonary Vascular Disease In Patients With Portal Hypertension - Results From A Prospective Cross-Sectional Study
AM J RESP CRIT CARE. 2017; 195: -International Conference of the American-Thoracic-Society (ATS); MAY 19-24, 2017; Washington, USA. [Oral Communication]
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** Golob-Schwarzl, N; Koller, C; Krassnig, S; Gogg-Kamerer, M; Gantenbein, N; Bergler, H; Pertschy, B; Uranitsch, S; Lackner, K; Puntschart, A; Stiegler, P; Keil, M; Hoffmann, J; Henderson, D; Lehrach, H; Reinhard, C; Schicho, R; Fickert, P; Lax, S; Haybaeck, J Translation initiation separates low and high grade colon and rectum carcinoma
EUR J CANCER. 2017; 72: S57-S57.-ECCO European Cancer Congress; JAN 27-30, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0959-8049(17)30267-8 [Oral Communication]
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** Golob-Schwarzl, N; Koller, C; Krassnig, S; Gogg-Kammerer, M; Gantenbein, N; Bergler, H; Pertschy, B; Uranitsch, S; Holter, M; El-Heliebi, A; Fuchs, J; Punschart, A; Stiegler, P; Keil, M; Hoffmann, J; Henderson, D; Lehrach, H; Reinhard, C; Schicho, R; Fickert, P; Lax, S; Haybaeck, J Translation initiation separates low and high grade and colon and rectum carcinoma
VIRCHOWS ARCH. 2017; 471: S167-S167. [Poster]
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** Golob-Schwarzl, N; Krassnig, S; Park, Y; Gogg-Kamerer, M; Wodlej, C; Vierlinger, K; Schroeder, F; Rhee, H; Schicho, R; Fickert, P; Haybaeck, J PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors as new biomarkers in liver cancer
VIRCHOWS ARCH. 2017; 471: S164-S164. [Poster]
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** Horvath, A; Bashir, M; Schmerboeck, B; Rainer, F; Krones, E; Baumann-Durchschein, F; Douschan, P; Spindelboeck, W; Zollner, G; Stauber, RE; Fickert, P; Stiegler, P; Leber, B; Stadlbauer, V Intestinal colonisation by Veillonella spp. is predictive for mortality in stable cirrhosis and could be partially reduced by a multispecies probiotic in a randomized placebo controlled trial
J HEPATOL. 2017; 66(1):S128-S128.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)30524-X [Poster]
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** Jungst, C; Stadlbauer, V; Reichert, M; Weber, S; Ofner-Ziegenfuss, L; Voigtlander, T; Spindelbock, W; Fickert, P; Kirchner, G; Lammert, F; Lankisch, TO; Krawczyk, M NOD2 variants as novel genetic risk factors for secondary sclerosing cholangitis in critically ill patients
J HEPATOL. 2017; 66(1):S358-S358.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. [Poster]
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** Kleinegger, F; Golob-Schwarzl, N; Toeglhofer, AM; Baran, P; Krassnig, S; Niedrist, T; Speicher, I; Rinner, B; Thalhammer, M; Aigelsreiter, A; Lackner, C; Scheller, J; Rose-John, S; Fickert, P; Haybaeck, J Interleukin-6 Receptor influences cholangiocarcinoma progression
VIRCHOWS ARCH. 2017; 471: S325-S326.-29th European Congress of Pathology; SEP 2-6, 2017; Amsterdam, The Netherlands. [Poster]
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** Leber, B; Horvath, A; Schmerbock, B; Tawdrous, M; Streit, A; Posch, A; Fickert, P; Spindelbock, W; Stiegler, P; Stauber, RE; Stadlbauer, V Direct acting antivirals improve neutrophil phagocytic capacity in chronic hepatitis C
J HEPATOL. 2017; 66(1):S293-S293.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)30902-9 [Poster]
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** Moustafa, T; Zaufel, A; Eichmann, T; Kolb-Lenz, D; Trauner, M; Fickert, P Regulation of the mechanistic target of rapamycin complex 1 (mTORC1) - nuclear hormone receptor signaling by bile acids
J HEPATOL. 2017; 66(1):S111-S111.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)30481-6 [Poster]
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** Rainer, F; Horvath, A; Sandahl, TD; Leber, B; Schmerboeck, B; Blesl, A; Krones, E; Baumann-Durchschein, F; Douschan, P; Spindelboeck, W; Zollner, G; Stauber, RE; Fickert, P; Stiegler, P; Moller, HJ; Gronbaek, H; Stadlbauer, V Macrophage activation markers sCD163 and mannose receptor predict survival and correlate with markers of gut permeability in patients with liver cirrhosis
J HEPATOL. 2017; 66(1):S368-S369.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)31080-2 [Poster]
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** Stadlbauer, V; Schmerbock, B; Leber, B; Kipperer, M; Stiegler, P; Posch, A; Streit, A; Spindelbock, W; Fickert, P; Stauber, R Drop of FGF19 levels in patients with HCC development following DAA therapy for chronic hepatitis C
J HEPATOL. 2017; 66(1):S710-S711.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)31903-7 [Poster]
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** Traussnigg, S; Schattenberg, JM; Demir, M; Wiegand, J; Geier, A; Teuber, G; Hofmann, WP; Kremer, AE; Spreda, F; Kluwe, J; Petersen, J; Boettler, T; Halilbasic, E; Greinwald, R; Proels, M; Manns, MP; Fickert, P; Trauner, MH norUrsodeoxycholic acid (norUDCA) improves non-alcoholic fatty liver disease (NAFLD): Results from a randomized placebo-controlled, double-blind phase IIa study
HEPATOLOGY. 2017; 66: 106A-107A.-68th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting; OCT 20-24, 2017; Washington, DC. [Oral Communication]
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2016

Originalarbeit (Zeitschrift)

** Baghdasaryan, A; Fuchs, CD; Österreicher, CH; Lemberger, UJ; Halilbasic, E; Påhlman, I; Graffner, H; Krones, E; Fickert, P; Wahlström, A; Ståhlman, M; Paumgartner, G; Marschall, HU; Trauner, M Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis.
J Hepatol. 2016; 64(3):674-681 Doi: 10.1016/j.jhep.2015.10.024 [OPEN ACCESS]
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** Graziadei, I; Zoller, H; Fickert, P; Schneeberger, S; Finkenstedt, A; Peck-Radosavljevic, M; Müller, H; Kohl, C; Sperner-Unterweger, B; Eschertzhuber, S; Hofer, H; Öfner, D; Tilg, H; Vogel, W; Trauner, M; Berlakovich, G Indications for liver transplantation in adults : Recommendations of the Austrian Society for Gastroenterology and Hepatology (ÖGGH) in cooperation with the Austrian Society for Transplantation, Transfusion and Genetics (ATX).
Wien Klin Wochenschr. 2016; 128(19-20):679-690 Doi: 10.1007/s00508-016-1046-1 [OPEN ACCESS]
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** Grumet, L; Eichmann, TO; Taschler, U; Zierler, KA; Leopold, C; Moustafa, T; Radovic, B; Romauch, M; Yan, C; Du, H; Haemmerle, G; Zechner, R; Fickert, P; Kratky, D; Zimmermann, R; Lass, A Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover.
J Biol Chem. 2016; 291(34):17977-87 Doi: 10.1074/jbc.M116.724054 [OPEN ACCESS]
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** Horvath, A; Leber, B; Schmerboeck, B; Tawdrous, M; Zettel, G; Hartl, A; Madl, T; Stryeck, S; Fuchs, D; Lemesch, S; Douschan, P; Krones, E; Spindelboeck, W; Durchschein, F; Rainer, F; Zollner, G; Stauber, RE; Fickert, P; Stiegler, P; Stadlbauer, V Randomised clinical trial: the effects of a multispecies probiotic vs. placebo on innate immune function, bacterial translocation and gut permeability in patients with cirrhosis.
Aliment Pharmacol Ther. 2016; 44(9):926-935 Doi: 10.1111/apt.13788 [OPEN ACCESS]
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** Reiter, FP; Wimmer, R; Wottke, L; Artmann, R; Nagel, JM; Carranza, MO; Mayr, D; Rust, C; Fickert, P; Trauner, M; Gerbes, AL; Hohenester, S; Denk, GU Role of interleukin-1 and its antagonism of hepatic stellate cell proliferation and liver fibrosis in the Abcb4(-/-) mouse model.
World J Hepatol. 2016; 8(8):401-410 Doi: 10.4254/wjh.v8.i8.401 [OPEN ACCESS]
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** Tang, Y; Fickert, P; Trauner, M; Marcus, N; Blomenkamp, K; Teckman, J Autophagy induced by exogenous bile acids is therapeutic in a model of α-1-AT deficiency liver disease.
Am J Physiol Gastrointest Liver Physiol. 2016; 311(1):G156-G165 Doi: 10.1152/ajpgi.00143.2015 [OPEN ACCESS]
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Editorial

** Wagner, M; Fickert, P; Zollner, G Secretin and cholestasis, two sides of a coin.
Hepatology. 2016; 64(3):714-716 Doi: 10.1002/hep.28687 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Bowe, A; Hoffmann, V; Curth, HM; Fickert, P; Nierhoff, D; CHOLESTASIS INDUCES EXPRESSION OF THE ONCOFETAL MARKER NOPE IN ADULT MURINE LIVER INDEPENDENT OF FXR.
J HEPATOL. 2016; 64: S427-S427.-EASL International Liver Congress; APR 13-17, 2016; Barcelona, SPAIN. Doi: 10.1016/S0168-8278(16)00692-9 [Oral Communication]
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** Grgic-Mustafic, R; Kahn, J; Podbregar, M; Holobar, A; Stauber, R; Fickert, P; Stadlbauer-Kollner, V; Nwoha, B; Muller, H; Kniepeiss, D A NEW METHOD FOR THE DETERMINATION AND MONITORING OF THE AMMONIA IN THE EXHALED AIR
TRANSPL INT. .. 2016; 29: 18-18. [Poster]
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** Horvath, A; Leber, B; Fuchs, D; Schmerboeck, B; Tawdrous, M; Yueksel, O; Sherzay, K; Hartl, A; Lemesch, S; Spindelboeck, W; Fickert, P; Stauber, RE; Stiegler, P; Durchschein, F; Krones, E; Douschan, P; Zollner, G; Stadlbauer, V; MULTISPECIES PROBIOTIC MAINTAINS HEALTH RELATED QUALITY OF LIFE IN CIRRHOSIS BETTER THAN PLACEBO.
J HEPATOL. 2016; 64: S249-S249.-EASL International Liver Congress; APR 13-17, 2016; Barcelona, SPAIN. Doi: 10.1016/S0168-8278(16)00262-2 [Poster]
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** Jungst, C; Stadlbauer, V; Reichert, MC; Ofner-Ziegenfuss, L; Voigtlander, T; Spindelboeck, W; Fickert, P; Kirchner, GI; Lammert, F; Lankisch, T; Krawczyk, M NOD2 confers risk for sclerosing cholangitis in critically ill patients: genetic study in two independent cohorts
HEPATOLOGY. 2016; 63(1 SUPP):191A-192A.-67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 11-15, 2016; Boston, MA. [Poster]
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** Krones, E; Bork, T; Grahammer, F; Wagner, M; Rosenkranz, AR; Huber, TB; Fickert, P ACCUMULATION OF LC3 II IN CHOLEMIC NEPHROPATHY IS CAUSED BY BLOCKAGE OF AUTOPHAGIC FLUX
NEPHROL DIAL TRANSPL. 2016; 31: 103-104.-53rd ERA-EDTA Congress; MAY 21-24, 2016; Vienna, AUSTRIA. [Poster]
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** Panzitt, K; Marschall, HU; Moore, DD; Trauner, MH; Fickert, P; Wagner, M The autophagy inhibitor Rubicon is a direct target of the bile acid receptor FXR in human liver and is induced in human cholestasis
HEPATOLOGY. 2016; 63(1 SUPP):159A-159A.-67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 11-15, 2016; Boston, MA. [Poster]
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** Schaffellner, S; Stauber, R; Sereinigg, M; Muller, H; Fickert, P; Hogenauer, C; Krumnikl, J; Lackner, C; Stadlbauer, V; Kniepeiss, D THE DOSE MAKES THE POISON: ACUTE LIVER FAILURE AFTER VITAMIN B3 OVERDOSAGE
TRANSPL INT. .. 2016; 29: 11-11. [Poster]
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** Stadlbauer, V; Fickert, P; Zink, M DEVELOPMENT OF AN APP TO FACILITATE AND IMPROVE THE ORGANIZATIONAL PROCESS IN ORGAN DONATION
TRANSPL INT. .. 2016; 29: 10-10. [Poster]
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** Trauner, M; Fickert, P; Hirschfield, G; Reiter, F; Altorjay, I; Marschall, U; Farkkila, M; Schramm, C; Spengler, U; Chapman, R; Bergquist, A; Schrumpf, E; Nevens, F; Halilbasic, E; Greinwald, R; Proels, M; Manns, MP; NORURSODEOXYCHOLIC ACID IMPROVES CHOLESTASIS IN PRIMARY SCLEROSING CHOLANGITIS: RESULTS OF A PHASE II DOSE FINDING STUDY.
J HEPATOL. 2016; 64: S208-S209.-EASL International Liver Congress; APR 13-17, 2016; Barcelona, SPAIN. Doi: 10.1016/S0168-8278(16)00171-9 [Oral Communication]
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** Trauner, MH; Fickert, P; Hirschfield, G; Denk, G; Altorjay, I; Marschall, HU; Farkkila, MA; Schramm, C; Spengler, U; Chapman, RW; Bergquist, A; Schrumpf, E; Nevens, F; Halilbasic, E; Greinwald, R; Prols, M; Manns, MP norUrsodeoxycholic acid (norUDCA) improves cholestasis in primary sclerosing cholangitis (PSC) independent of ursodeoxycholic acid (UDCA) pre-treatment and response
HEPATOLOGY. 2016; 63(1 SUPP):111A-111A.-67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 11-15, 2016; Boston, MA. [Oral Communication]
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Kommentar

** Krones, E; Erwa, W; Trauner, M; Fickert, P Reply.
Hepatology. 2016; 63(1):346-347 Doi: 10.1002/hep.27873 [OPEN ACCESS]
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2015

Originalarbeit (Zeitschrift)

** Chen, Y; Guldiken, N; Spurny, M; Mohammed, HH; Haybaeck, J; Pollheimer, MJ; Fickert, P; Gassler, N; Jeon, MK; Trautwein, C; Strnad, P Loss of keratin 19 favours the development of cholestatic liver disease through decreased ductular reaction.
J Pathol. 2015; 237(3):343-354 Doi: 10.1002/path.4580
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** Fabian, E; Madl, C; Horn, S; Kornprat, P; Maderthaner, R; Aigelsreiter, A; Krause, R; Fickert, P; Krejs, GJ Clinical-pathological conference series from the Medical University of Graz: case no. 151: 19-year-old student from Albania with emergency admission due to shock.
Wien Klin Wochenschr. 2015; 127(3-4):151-159 Doi: 10.1007/s00508-014-0636-z
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** Hackl, G; Portugaller, RH; Fickert, P Emergency Double-Stenting and Surgery for the Successful Management of Massive Upper Gastrointestinal Bleeding Caused by Mycotic Aortic Aneurysm.
Clin Gastroenterol Hepatol. 2015; 13(13):e171-e172 Doi: 10.1016/j.cgh.2015.04.016 (- Case Report) [OPEN ACCESS]
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** Krones, E; Fickert, P; Zitta, S; Neunherz, S; Artinger, K; Reibnegger, G; Durchschein, F; Wagner, D; Stojakovic, T; Stadlbauer, V; Fauler, G; Stauber, R; Zollner, G; Kniepeiss, D; Rosenkranz, AR The chronic kidney disease epidemiology collaboration equation combining creatinine and cystatin C accurately assesses renal function in patients with cirrhosis.
BMC Nephrol. 2015; 16(4):196-196 Doi: 10.1186/s12882-015-0188-0 [OPEN ACCESS]
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** Sombetzki, M; Fuchs, CD; Fickert, P; Österreicher, CH; Mueller, M; Claudel, T; Loebermann, M; Engelmann, R; Langner, C; Sahin, E; Schwinge, D; Guenther, ND; Schramm, C; Mueller-Hilke, B; Reisinger, EC; Trauner, M 24-nor-ursodeoxycholic acid ameliorates inflammatory response and liver fibrosis in a murine model of hepatic schistosomiasis.
J Hepatol. 2015; 62(4):871-878 Doi: 10.1016/j.jhep.2014.11.020 [OPEN ACCESS]
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** Stadlbauer, V; Leber, B; Lemesch, S; Trajanoski, S; Bashir, M; Horvath, A; Tawdrous, M; Stojakovic, T; Fauler, G; Fickert, P; Högenauer, C; Klymiuk, I; Stiegler, P; Lamprecht, M; Pieber, TR; Tripolt, NJ; Sourij, H Lactobacillus casei Shirota Supplementation Does Not Restore Gut Microbiota Composition and Gut Barrier in Metabolic Syndrome: A Randomized Pilot Study.
PLoS One. 2015; 10(10):e0141399-e0141399 Doi: 10.1371/journal.pone.0141399 [OPEN ACCESS]
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Kurzbericht/Letter

** Krones, E; Erwa, W; Trauner, M; Fickert, P Serum alkaline phosphatase levels accurately reflect cholestasis in mice.
Hepatology. 2015; 62(3):981-983 Doi: 10.1002/hep.27622 [OPEN ACCESS]
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Übersichtsarbeit

** Krones, E; Wagner, M; Eller, K; Rosenkranz, AR; Trauner, M; Fickert, P Bile acid-induced cholemic nephropathy.
Dig Dis. 2015; 33(3):367-375 Doi: 10.1159/000371689
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** Pollheimer, MJ; Fickert, P Animal models in primary biliary cirrhosis and primary sclerosing cholangitis.
Clin Rev Allergy Immunol. 2015; 48(2-3): 207-217. Doi: 10.1007/s12016-014-8442-y
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** Trauner, M; Halilbasic, E; Claudel, T; Steinacher, D; Fuchs, C; Moustafa, T; Pollheimer, M; Krones, E; Kienbacher, C; Traussnigg, S; Kazemi-Shirazi, L; Munda, P; Hofer, H; Fickert, P; Paumgartner, G Potential of nor-Ursodeoxycholic Acid in Cholestatic and Metabolic Disorders.
Dig Dis. 2015; 33(3):433-439 Doi: 10.1159/000371904
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Abstract (Zeitschrift)

** Bowe, A; Hoffmann, V; Curth, HM; Fickert, P; Nierhoff, D CHOLESTASIS AND BILE ACIDS INDUCE EXPRESSION OF THE ONCOFETAL MARKER Nope IN ADULT MURINE HEPATOCYTES INDEPENDENT OF FXR
J HEPATOL. 2015; 62: S799-S799.-50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver; APR 22-26, 2015; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(15)31382-9
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** Horvath, A; Leber, B; Krones, E; Zollner, G; Durchschein, F; Spindelboeck, W; Lemesch, S; Douschan, P; Fauler, G; Stojakovic, T; Fickert, P; Stauber, R; Stiegler, P; Stadlbauer, V SERUM BILE ACIDS IN CIRRHOSIS DEPEND ON AETIOLOGY.
J HEPATOL. 2015; 62(S2):S344-S344.-50th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 22-26, 2015; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(15)30336-6 [Poster]
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** Horvath, A; Leber, B; Schmerboeck, B; Tawdrous, M; Hartl, A; Lemesch, S; Fickert, P; Stauber, RE; Stiegler, P; Durchschein, F; Krones, E; Douschan, P; Zollner, G; Spindelboeck, W; Oettl, K; Payerl, D; Stadlbauer, V Probiotic supplementation improves liver function but fails to restore neutrophil phagocytosis in stable cirrhosis. A randomized, double-blind, placebo-controlled study
HEPATOLOGY. . 2015; 62: 1216A-1216A.-66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 13-17, 2015; San Francisco, CA. [Oral Communication]
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** Panzitt, K; Marschall, HU; Trauner, M; Fickert, P; Wagner, M Effects of Ursodeoxycholic-acid and Rifampicin on autophagy in the liver
HEPATOLOGY. . 2015; 62: 538A-538A.-66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 13-17, 2015; San Francisco, CA. [Oral Communication]
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2014

Originalarbeit (Zeitschrift)

** Hochrath, K; Stokes, CS; Geisel, J; Pollheimer, MJ; Fickert, P; Dooley, S; Lammert, F Vitamin D modulates biliary fibrosis in ABCB4-deficient mice.
Hepatol Int. 2014; 8(3):443-452 Doi: 10.1007/s12072-014-9548-2 [OPEN ACCESS]
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** Jahnel, J; Fickert, P; Hauer, AC; Högenauer, C; Avian, A; Trauner, M Inflammatory bowel disease alters intestinal bile acid transporter expression.
Drug Metab Dispos. 2014; 42(9):1423-1431 Doi: 10.1124/dmd.114.058065 [OPEN ACCESS]
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** Woolbright, BL; Li, F; Xie, Y; Farhood, A; Fickert, P; Trauner, M; Jaeschke, H Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice.
Toxicol Lett. 2014; 228(1):56-66 Doi: 10.1016/j.toxlet.2014.04.001 [OPEN ACCESS]
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** Yang, M; Ramachandran, A; Yan, HM; Woolbright, BL; Copple, BL; Fickert, P; Trauner, M; Jaeschke, H Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice.
Toxicol Lett. 2014; 224(2):186-195 Doi: 10.1016/j.toxlet.2013.10.030 [OPEN ACCESS]
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** Zollner, G; Thueringer, A; Lackner, C; Fickert, P; Trauner, M Alterations of canalicular ATP-binding cassette transporter expression in drug-induced liver injury.
Digestion. 2014; 90(2):81-88 Doi: 10.1159/000365003
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Übersichtsarbeit

** Fickert, P; Pollheimer, MJ; Beuers, U; Lackner, C; Hirschfield, G; Housset, C; Keitel, V; Schramm, C; Marschall, HU; Karlsen, TH; Melum, E; Kaser, A; Eksteen, B; Strazzabosco, M; Manns, M; Trauner, M; International PSC Study Group (IPSCSG) Characterization of animal models for primary sclerosing cholangitis (PSC).
J Hepatol. 2014; 60(6):1290-1303 Doi: 10.1016/j.jhep.2014.02.006 [OPEN ACCESS]
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** Pollheimer, MJ; Fickert, P; Stieger, B Chronic cholestatic liver diseases: clues from histopathology for pathogenesis.
Mol Aspects Med. 2014; 37(2):35-56 Doi: 10.1016/j.mam.2013.10.001
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Editorial

** Fickert, P; Stieger, B Molecular pathogenesis of chronic cholestatic liver disease: impact on novel therapeutic approaches.
Mol Aspects Med. 2014; 37(6):1-2 Doi: 10.1016/j.mam.2013.11.001
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Abstract (Zeitschrift)

** Hofer, H; Zollner, G; Fickert, P; Graziadei, I; Trauner, M Clinical Course And Outcome Of Patients With Sclerosing Cholangitis In Critically Ill Patients (Sc-Cip): High Mortality Without Liver Transplantation
HEPATOLOGY. 2014; 60: 354A-354A.-65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 07-11, 2014; Boston, MA. [Poster]
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** Horvath, A; Leber, B; Lemesch, S; Suppan, O; Yuksel, O; Sherzay, K; Zettel, G; Tawdrous, M; Spindelboeck, W; Durchschein, F; Krones, E; Douschan, P; Zollner, G; Fickert, P; Stauber, R; Stiegler, P; Stadlbauer, V LISTING FOR LIVER TRANSPLANT: NO IMPACT ON THE QUALITY OF LIFE
TRANSPL INT. 2014; 27: 20-21. [Poster]
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** Krones, E; Fritz, J; Schwarz, C; Durchschein, F; Eller, K; Zollner, G; Ribitsch, W; Stojakovic, T; Zitta, S; Buchgraber, J; Eppich, S; Rosenkranz, A; Fickert, P Pathologische Harnzytologie als Hinweis für strukturelle Nierenschäden bei PatientInnen mit Zirrhose und Cholestase mit normaler Nierenfunktion.
WIEN KLIN WOCHENSCHR. 2014; 126(17-18):566-566.-45. Jahrestagung der Österreichischen Gesellschaft für Innere Medizin (ÖGIM); SEP 25-27, 2014; Salzburg, AUSTRIA. [Poster]
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** Krones, E; Fritz, J; Schwarz, C; Durchschein, F; Eller, K; Zollner, G; Ribitsch, W; Stojakovic, T; Zitta, S; Buchgrabner, J; Rosenkranz, AR; Fickert, P Microscopic Urinanalysis May Represent a Sensitive Test for Kidney Injury in Cirrhotic and Cholestatic Patients with Preserved Kidney Function.
HEPATOLOGY. 2014; 60: 328A-328A.-65th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 07-11, 2014; Boston, USA. [Poster]
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** Krones, E; Glaenzer, D; Durchschein, F; Kirsch, A; Eller, K; Trauner, M; Rosenkranz, AR; Fickert, P Urinary NGAL Levels Reflect the Therapeutic Effects of norUDCA in Mice with Cholemic Nephropathy
HEPATOLOGY. 2014; 60: 329A-329A.-65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 07-11, 2014; Boston, MA. [Poster]
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** Krones, E; Glanzer, D; Durchschein, F; Kirsch, A; Eller, K; Trauner, M; Rosenkranz, A; Fickert, P Urinary NGAL Levels reflect the therapeutic Effects of norUDCA in the Mouse Model of cholemic Nephropathy
WIEN KLIN WOCHENSCHR. 2014; 126(17-18):577-577.-65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 07-11, 2014; Boston, MA. [Poster]
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** Krones, E; Zitta, S; Neunherz, S; Artinger, K; Stojakovic, T; Reibnegger, G; Durchschein, F; Buchgrabner, J; Stadlbauer, V; Fickert, P; Rosenkranz, AR Chronic Kidney Disease Epidemiology Collaboration Equation combining Creatinine and Cystatin C is superior to other Creatine- and Cystatin C-based Equations in Assessing Renal Function in Patients with Cirrhosis.
HEPATOLOGY. 2014; 60: 325A-325A.-65th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 07-11, 2014; Boston, USA. [Poster]
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** Krones, E; Zitta, S; Neunherz, S; Artinger, K; Stojakovic, T; Reibnegger, G; Durchschein, F; Stadlbauer-Kollner, V; Fickert, P; Rosenkranz, A The CKD-EPI Formula, Creatinine and Cystatin C used in combination, is superior to another Creatinine- and Cystatin C based Formulas for Renal Function Determination in Cirrhosis.
WIEN KLIN WOCHENSCHR. 2014; 126(17-18):577-577.-45. Jahrestagung der Österreichischen Gesellschaft für Innere Medizin (ÖGIM); SEP 25-27, 2014; Salzburg, AUSTRIA. [Poster]
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** Zaufel, A; Wagner, M; Krones, E; Fickert, P; Zollner, G Cholestasis and Bile Acids start the Adrenocortical Function, Salzburg, 25th-27th September, 2014
WIEN KLIN WOCHENSCHR. 2014; 126(17-18):570-571. [Poster]
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Kommentar

** Fickert, P Time to say goodbye to the drug or the model? - why do drugs fail to live up to their promise in bile duct ligated mice?
J Hepatol. 2014; 60(1):12-15 Doi: 10.1016/j.jhep.2013.09.019 [OPEN ACCESS]
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2013

Originalarbeit (Zeitschrift)

** Acimovic, J; Lövgren-Sandblom, A; Olin, M; Ali, Z; Heverin, M; Schüle, R; Schöls, L; Fischler, B; Fickert, P; Trauner, M; Björkhem, I Sulphatation does not appear to be a protective mechanism to prevent oxysterol accumulation in humans and mice.
PLoS One. 2013; 8(7):e68031-e68031 Doi: 10.1371/journal.pone.0068031 [OPEN ACCESS]
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** Fickert, P; Krones, E; Pollheimer, MJ; Thueringer, A; Moustafa, T; Silbert, D; Halilbasic, E; Yang, M; Jaeschke, H; Stokman, G; Wells, RG; Eller, K; Rosenkranz, AR; Eggertsen, G; Wagner, CA; Langner, C; Denk, H; Trauner, M Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice.
Hepatology. 2013; 58(6):2056-2069 Doi: 10.1002/hep.26599 [OPEN ACCESS]
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** Fickert, P; Pollheimer, MJ; Silbert, D; Moustafa, T; Halilbasic, E; Krones, E; Durchschein, F; Thüringer, A; Zollner, G; Denk, H; Trauner, M Differential effects of norUDCA and UDCA in obstructive cholestasis in mice.
J Hepatol. 2013; 58(6):1201-1208 Doi: 10.1016/j.jhep.2013.01.026 [OPEN ACCESS]
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** Marzioni, M; Saccomanno, S; Agostinelli, L; Rychlicki, C; De Minicis, S; Pierantonelli, I; Trauner, M; Fickert, P; Müller, T; Shanmukhappa, K; Trozzi, L; Candelaresi, C; Baroni, GS; Benedetti, A PDX-1/Hes-1 interactions determine cholangiocyte proliferative response to injury in rodents: possible implications for sclerosing cholangitis.
J Hepatol. 2013; 58(4):750-756 Doi: 10.1016/j.jhep.2012.11.033
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** Putz-Bankuti, C; Kessler, HH; Valentin, T; Leitner, E; Talakic, E; Schoellnast, H; Fickert, P; Krejs, GJ; Stauber, RE Pleuro-Pulmonary Nocardiosis as Opportunistic Infection in a Patient with Chronic Hepatitis C under Combination Treatment with Pegylated Interferon, Ribavirin, and Boceprevir.
Case Reports Hepatol. 2013; 2013:529041 Doi: 10.1155/2013/529041 [OPEN ACCESS]
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Abstract (Zeitschrift)

** A, Horvath; B, Leber; S, Lemesch; P, Stiegler; R, Stauber; P, Fickert; G, Zollner; W, Spindelboeck; E, Krones; F, Durchschein; P, Douschan; V, Stadlbauer INCREASED GUT PERMEABILITY, ELEVATED ENDOTOXIN RELATED PROTEINS AND NEUTROPHIL DYSFUNCTION IN LIVER CIRRHOSIS.
Journal of Hepatology. 2013; 58(S1):S104--48th Annual meeting of the European Association for the Study of the Liver ; 24 April 2013 - 28 April 2013; Amsterdam. Doi: 10.1016/S0168-8278(13)60246-9 [Poster]
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** Krones, E; Pollheimer, MJ; Deutschmann, A; Kinslechner, K; Durchschein, F; Eller, K; Rosenkranz, A; Trauner, M; Fickert, P norUDCA AMELIORATES CHOLEMIC NEPHROPATHY IN LONG-TERM COMMON BILE DUCT LIGATED MICE
J HEPATOL. 2013; 58: S43-S43. Doi: 10.1016/S0168-8278(13)60100-2 [Oral Communication]
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** Leber, B; Tripolt, N; Lemesch, S; Horvath, A; Stojakovic, T; Fauler, G; Stauber, R; Fickert, P; Sourij, H; Stadlbauer, V INCREASED GUT PERMEABILITY IN METABOLIC SYNDROME IS NOT ASSOCIATED WITH CHANGES IN BILE ACID PROFILE.
J HEPATOL. 2013; 58(S1):S549-S550.-48th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 24-28, 2013; Amsterdam, THE NETHERLANDS. Doi: 10.1016/S0168-8278(13)61366-5 [Poster]
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** Mueller, M; Marschall, HU; Claudel, T; Wagner, M; Fickert, P; Lackner, C; Einarsson, C; Thorell, A; Trauner, M URSODEOXYCHOLIC ACID COUNTERACTS LIPOTOXICITY AND INDUCES UNFOLDED PROTEIN RESPONSE IN MORBIDLY OBESE PATIENTS
J HEPATOL. . 2013; 58: S517-S517.-International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 24-28, 2013; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(13)61279-9 [Poster]
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** Pollheimer, MJ; Bowlus, C; Lackner, C; Karlsen, TH; Hov, JR; Lyman, S; Adamkewicz, J; Mikels-Vigdal, A; Marshall, D; Smith, V; Trauner, M; Fickert, P LYSYL OXIDASE-LIKE 2 (LOXL2) PROTEIN IS INDUCED IN HUMAN CHOLESTATIC LIVER DISEASE AND IN ANIMAL MODELS OF CHOLANGIOPATHIES
J HEPATOL. 2013; 58: S281-S282. Doi: 10.1016/S0168-8278(13)60696-0 [Poster]
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** Teckman, J; Fickert, P; Trauner, M Autophagy is induced by the bile acid norUDCA, which may be a potential therapy for alpha-1-antitrypsin deficiency
HEPATOLOGY. .. 2013; 58: 257A-257A.-64th Annual Meeting and Postgraduate Course of the American-Association-for-the-Study-of-Liver-Diseases; NOV 01-05, 2013; Washington, DC. [Poster]
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Kommentar

** Trauner, M; Fickert, P; Tilg, H Bile acids as modulators of gut microbiota linking dietary habits and inflammatory bowel disease: a potentially dangerous liaison.
Gastroenterology. 2013; 144(4):844-846 Doi: 10.1053/j.gastro.2013.02.029
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2012

Originalarbeit (Zeitschrift)

** Bernhardt, GA; Zollner, G; Cerwenka, H; Kornprat, P; Fickert, P; Bacher, H; Werkgartner, G; Müller, G; Zatloukal, K; Mischinger, HJ; Trauner, M Hepatobiliary transporter expression and post-operative jaundice in patients undergoing partial hepatectomy.
Liver Int. 2012; 32(1):119-127 Doi: 10.1111/j.1478-3231.2011.02625.x
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** Haybaeck, J; Stumptner, C; Thueringer, A; Kolbe, T; Magin, TM; Hesse, M; Fickert, P; Tsybrovskyy, O; Müller, H; Trauner, M; Zatloukal, K; Denk, H Genetic background effects of keratin 8 and 18 in a DDC-induced hepatotoxicity and Mallory-Denk body formation mouse model.
Lab Invest. 2012; 92(6):857-867 Doi: 10.1038/labinvest.2012.49 [OPEN ACCESS]
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Silbert, D; Gustafsson, U; Sahlin, S; Trauner, M Combined rifampicin and ursodeoxycholic acid treatment does not amplify rifampicin effects on hepatic detoxification and transport systems in humans.
Digestion. 2012; 86(3):244-249 Doi: 10.1159/000341420
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** Moustafa, T; Fickert, P; Magnes, C; Guelly, C; Thueringer, A; Frank, S; Kratky, D; Sattler, W; Reicher, H; Sinner, F; Gumhold, J; Silbert, D; Fauler, G; Höfler, G; Lass, A; Zechner, R; Trauner, M Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Gastroenterology. 2012; 142(1):140-151 Doi: 10.1053/j.gastro.2011.09.051
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Übersichtsarbeit

** Krones, E; Graziadei, I; Trauner, M; Fickert, P Evolving concepts in primary sclerosing cholangitis.
Liver Int. 2012; 32(3):352-369 Doi: 10.1111/j.1478-3231.2011.02607.x [OPEN ACCESS]
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** Trauner, M; Halilbasic, E; Baghdasaryan, A; Moustafa, T; Krones, E; Fickert, P; Hofer, H; Penner, E Primary sclerosing cholangitis: new approaches to diagnosis, surveillance and treatment.
Dig Dis. 2012; 30 Suppl 1(6):39-47 Doi: 10.1159/000341123
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Abstract (Zeitschrift)

** Durchschein, F; Pollheimer, MJ; Krones, E; Zollner, G; Trauner, M; Fickert, P Genetic Loss of Muscarine-3 Receptor Decreases Biliary Bicarbonate Secretion and Aggravates Cholestatic Liver Injury in Mice
HEPATOLOGY. 2012; 56: 334A-334A.-63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 09-13, 2012; Boston, MA.
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** Halilbasic, E; Claudel, T; Bachhofner, N; Kapusta, C; Fickert, P; Trauner, M Norursodeoxycholic Acid Counteracts Hepatic Acute Phase Response via Modulation of NF kappa B Signaling
HEPATOLOGY. 2012; 56: 539A-540A.-63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 09-13, 2012; Boston, MA.
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** Krones, E; Pollheimer, MJ; Durchschein, F; Trauner, M; Fickert, P The effects of bile acids on renal collecting duct epithelial cell death - are bile acids the culprits in cholemic nephropathy?
HEPATOLOGY. 2012; 56: 544A-545A.-63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 09-13, 2012; Boston, MA. [Poster]
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** Marschall, HU; Mueller, M; Wagner, M; Fickert, P; Zollner, G; Silbert, D; Lackner, C; Thorell, A; Trauner, M HIGH LEVELS OF URSODEOXYCHOLIC ACID ACT AS FXR ANTAGONIST AND DEPLETE LIVER CHOLESTEROL DUE TO INCREASED BILE ACID SYNTHESIS IN MORBIDLY OBESE PATIENTS
J HEPATOL. . 2012; 56: S515-S515.-47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN. Doi: 10.1016/S0168-8278(12)61319-1 [Poster]
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** Marzioni, M; Saccomanno, S; Agostinelli, L; Rychlicki, C; Pierantonelli, I; Trauner, M; Fickert, P; Mueller, T; Shanmukhappa, SK; Trozzi, L; De Minicis, S; Candelaresi, C; Svegliati-Baroni, G; Benedetti, A PDX-1/Hes-1 interaction is a determinant of cholangiocyte proliferative response in Sclerosing Cholangitis
HEPATOLOGY. 2012; 56: 207A-207A.-63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 09-13, 2012; Boston, MA.
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** Marzioni, M; Saccomanno, S; Agostinelli, L; Rychlicki, C; Pierantonelli, I; Trauner, M; Fickert, P; Muller, T; Shanmukhappa, K; Alpini, G; Trozzi, L; De Minicis, S; Candelaresi, C; Baroni, GS; Benedetti, A PDX-1/HES-1 INTERACTIONS DETERMINE CHOLANGIOCYTE PROLIFERATIVE RESPONSE TO INJURY: THE SIGNIFICANCE FOR SCLEROSING CHOLANGITIS
J HEPATOL. 2012; 56: S16-S16.-47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN. Doi: 10.1016/S0168-8278(12)60050-6
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2011

Originalarbeit (Zeitschrift)

** Baghdasaryan, A; Claudel, T; Gumhold, J; Silbert, D; Adorini, L; Roda, A; Vecchiotti, S; Gonzalez, FJ; Schoonjans, K; Strazzabosco, M; Fickert, P; Trauner, M Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output.
Hepatology. 2011; 54(4):1303-1312 Doi: 10.1002/hep.24537 [OPEN ACCESS]
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Lackner, C; Thorell, A; Trauner, M Ursodeoxycholic acid for treatment of fatty liver disease and dyslipidemia in morbidly obese patients.
Dig Dis. 2011; 29(1):117-118 Doi: 10.1159/000324146
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Kurzbericht/Letter

** Kniepeiss, D; Wagner, D; Krause, R; Aigelsreiter, A; Iberer, F; Fickert, P; Tscheliessnigg, KH; Trauner, M Mycosis as a cause of secondary sclerosing cholangitis requiring liver retransplantation.
Transplantation. 2011; 91(2):e14-e16 Doi: 10.1097/TP.0b013e318200ba57 (- Case Report) [OPEN ACCESS]
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Übersichtsarbeit

** Pollheimer, MJ; Halilbasic, E; Fickert, P; Trauner, M Pathogenesis of primary sclerosing cholangitis.
Best Pract Res Clin Gastroenterol. 2011; 25(6):727-739 Doi: 10.1016/j.bpg.2011.10.009 [OPEN ACCESS]
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** Pollheimer, MJ; Trauner, M; Fickert, P Will we ever model PSC? - "it's hard to be a PSC model!".
Clin Res Hepatol Gastroenterol. 2011; 35(12):792-804 Doi: 10.1016/j.clinre.2011.04.014
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** Trauner, M; Baghdasaryan, A; Claudel, T; Fickert, P; Halilbasic, E; Moustafa, T; Zollner, G Targeting nuclear bile acid receptors for liver disease.
Dig Dis. 2011; 29(1):98-102 Doi: 10.1159/000324141
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Abstract (Zeitschrift)

** Baghdasaryan, A; Claudel, T; Gumhold, J; Silbert, D; Adorini, L; Gonzalez, F; Schoonjans, K; Fickert, P; Trauner, M FXR BUT NOT TGR5 ACTIVATION STIMULATES HCO3-RICH BILE SECRETION AND AMELIORATES LIVER DAMAGE IN MDR2-/- (ABCB4-/-) MOUSE MODEL OF CHRONIC LIVER INJURY
HEPATOLOGY. 2011; 54: 425A-425A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA. [Oral Communication]
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** Fickert, P; Silbert, D; Moustafa, T; Halilbasic, E; Krones, E; Durchschein, F; Thueringer, A; Pollheimer, MJ; Zollner, G; Denk, H; Trauner, M DIFFERENTIAL EFFECTS OF NORUDCA AND UDCA IN OBSTRUCTIVE CHOLESTASIS IN MICE
HEPATOLOGY. 2011; 54: 775A-775A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA. [Poster]
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** Fickert, P; Thueringer, A; Moustafa, T; Silbert, D; Yang, M; Jaeschke, H; Stokman, G; Wells, R; Eller, K; Rosenkranz, AR; Eggertsen, G; Denk, H; Trauner, M TUBULOINTERSTITIAL KIDNEY FIBROSIS AND CHRONIC RENAL FAILURE IN LONG-TERM COMMON BILE-DUCT-LIGATED MICE AS A RESULT OF COLLECTING DUCT INJURY: THE ROLE OF OSTEOPONTIN, FXR, AND CYP8B1
HEPATOLOGY. 2011; 54: 1250A-1251A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA.
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** Fickert, P; Thueringer, A; Moustafa, T; Yang, M; Jaeschke, H; Wells, RG; Stokman, G; Denk, H; Trauner, M LONG-TERM COMMON BILE DUCT-LIGATION IN MICE INDUCES TUBULOINTERSTITIAL KIDNEY FIBROSIS AND CHRONIC RENAL FAILURE: ROLE OF BILE ACID NUCLEAR RECEPTOR FXR AND OSTEOPONTIN
J HEPATOL. 2011; 54: S244-S244.-46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); 2011; Berlin, GERMANY. Doi: 10.1016/S0168-8278(11)60602-8
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** Pollheimer, MJ; Fickert, P; Langner, C; Karlsen, TH; Trauner, M ADHESION MOLECULE EXPRESSION PATTERN IN PRIMARY SCLEROSING CHOLANGITIS AND DISEASE CONTROLS
J HEPATOL. 2011; 54: S516-S516. Doi: 10.1016/S0168-8278(11)61312-3 [Poster]
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2010

Originalarbeit (Zeitschrift)

** Baghdasaryan, A; Claudel, T; Kosters, A; Gumhold, J; Silbert, D; Thüringer, A; Leski, K; Fickert, P; Karpen, SJ; Trauner, M Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation.
Gut. 2010; 59(4):521-530 Doi: 10.1136/gut.2009.186528 [OPEN ACCESS]
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** Denk, GU; Maitz, S; Wimmer, R; Rust, C; Invernizzi, P; Ferdinandusse, S; Kulik, W; Fuchsbichler, A; Fickert, P; Trauner, M; Hofmann, AF; Beuers, U Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver.
Hepatology. 2010; 52(5): 1758-1768. Doi: 10.1002/hep.23911 [OPEN ACCESS]
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** Fickert, P; Thueringer, A; Moustafa, T; Silbert, D; Gumhold, J; Tsybrovskyy, O; Lebofsky, M; Jaeschke, H; Denk, H; Trauner, M The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in mice.
Lab Invest. 2010; 90(6):844-852 Doi: 10.1038/labinvest.2010.61 [OPEN ACCESS]
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** Mair, M; Zollner, G; Schneller, D; Musteanu, M; Fickert, P; Gumhold, J; Schuster, C; Fuchsbichler, A; Bilban, M; Tauber, S; Esterbauer, H; Kenner, L; Poli, V; Blaas, L; Kornfeld, JW; Casanova, E; Mikulits, W; Trauner, M; Eferl, R Signal transducer and activator of transcription 3 protects from liver injury and fibrosis in a mouse model of sclerosing cholangitis.
Gastroenterology. 2010; 138(7):2499-2508 Doi: 10.1053/j.gastro.2010.02.049
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Übersichtsarbeit

** Trauner, M; Claudel, T; Fickert, P; Moustafa, T; Wagner, M Bile acids as regulators of hepatic lipid and glucose metabolism.
Dig Dis. 2010; 28(1):220-224 Doi: 10.1159/000282091
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** Trauner, M; Fickert, P; Baghdasaryan, A; Claudel, T; Halilbasic, E; Moustafa, T; Wagner, M; Zollner, G New insights into autoimmune cholangitis through animal models.
Dig Dis. 2010; 28(1):99-104 Doi: 10.1159/000282072
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Abstract (Zeitschrift)

** Baghdasaryan, A; Claudel, T; Gumhold, J; Silbert, D; Halsegger, S; Adorini, L; Strazzabosco, M; Fickert, P; Trauner, M THERAPEUTIC TARGETING OF NUCLEAR AND MEMBRANE BILE ACID RECEPTORS IN A MOUSE MODEL OF CHRONIC CHOLESTASIS
HEPATOLOGY. 2010; 52(4):724--The 61st Annual Meeting of the Americal Association fro teh Study of liver Diseases; OCT 29-NOV 02, 2010; Boston, MA, USA. [Poster]
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** Baghdasaryan, A; Claudel, T; Gumhold, J; Silbert, D; Halsegger, S; Volkl, R; Adorini, L; Fickert, P; Trauner, M THERAPEUTIC EFFECTS OF FXR AND TGR5 ACTIVATION IN THE MDR2 (ABCB4)(-/-) MOUSE MODEL OF SCLEROSING CHOLANGITIS
J HEPATOL. 2010; 52: S354-S354.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)60914-2 [Oral Communication]
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** Fuchs, CD; Moustafa, T; Haemmerle, G; Halilbasic, E; Gumhold, J; Silbert, D; Fickert, P; Zechner, R; Trauner, M ADIPOSE TRIGLYCERIDE LIPASE (ATGL) IS A NOVEL MODULATOR OF HEPATIC ER-STRESS
J HEPATOL. 2010; 52: S305-S305.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)60787-8 [Oral Communication]
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** Halilbasic, E; Claudel, T; Gumhold, J; Halsegger, S; Silbert, D; Fickert, P; Trauner, M PREGNANCY RESOLVES LIVER FIBROSIS AND IMPROVES SCLEROSING CHOLANGITIS IN MDR2 (ABCB4) -/- MICE VIA DIRECT ANTI-INFLAMMATORY EFFECTS OF SEX HORMONES
J HEPATOL. 2010; 52: S24-S24.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)60052-9 [Oral Communication]
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** Krones, E; Halilbasic, E; Grisold, A; Krause, R; Trauner, M; Fickert, P; Zollner, G Acute hepatitis species as a result of contamination of a food supplement with Cytotoxin-producing Bacillus species.
WIEN KLIN WOCHENSCHR. 2010; 122(17-18):A10-A11. [Poster]
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** Mader, JK; Bock, G; Wagner, M; Forrer, F; Lackner, C; Portugaller, RH; Fickert, P; Krejs, GJ; Pieber, TR Recurrent hypoglycemia in adults - a diagnostic challenge (case report).
WIEN KLIN WOCHENSCHR. 2010; 122(17-18):A7-A7.-ÖGIM; Sep 29-Oct. 1; Salzburg, Austria. [Poster]
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** Moustafa, T; Fickert, P; Magnes, C; Frank, S; Kratky, D; Sinner, F; Gumhold, J; Silbert, D; Halsegger, S; Trauner M METABOLIC REPROGRAMMING OF LIPID METABOLISM BY THE SIDE-CHAIN MODIFIED BILE ACID, 24-NORURSODEOXYCHOLIC ACID, RESTORES INFLAMMATION-DRIVEN LIVER INJURY AND ABERRANT PROLIFERATION IN ABCB4-/- MICE
J HEPATOL. 2010; 52: S20-S21.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)60049-9 [Oral Communication]
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** Pichler, M; Beham-Schmid, C; Lackner, K; Linkesch, W; Fickert, P; Emberger, W; Schmidt, H Cholestatic hepatitis due to diffuse liver infiltration by Acute myelogenous leukemia with inv(16)(p13;q22): A case report and review of the literature
ONKOLOGIE. 2010; 33: 141-141.-Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie; Oct 1 -5, 2010; Berlin, Germany. [Poster]
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** Zollner, G; Thueringer, A; Lackner, C; Fickert, P; Trauner, M ALTERATIONS OF CANALICULAR ATP-BINDING CASSETTE TRANSPORTERS IN PATIENTS WITH DRUG-INDUCED LIVER INJURY
J HEPATOL. 2010; 52: S449-S449.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)61163-4 [Poster]
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2009

Originalarbeit (Zeitschrift)

** Fickert, P; Fuchsbichler, A; Moustafa, T; Wagner, M; Zollner, G; Halilbasic, E; Stöger, U; Arrese, M; Pizarro, M; Solís, N; Carrasco, G; Caligiuri, A; Sombetzki, M; Reisinger, E; Tsybrovskyy, O; Zatloukal, K; Denk, H; Jaeschke, H; Pinzani, M; Trauner, M Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts.
Am J Pathol. 2009; 175(6):2392-2405 Doi: 10.2353/ajpath.2009.090114 [OPEN ACCESS]
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** Fickert, P; Fuchsbichler, A; Wagner, M; Silbert, D; Zatloukal, K; Denk, H; Trauner, M The role of the hepatocyte cytokeratin network in bile formation and resistance to bile acid challenge and cholestasis in mice.
Hepatology. 2009; 50(3):893-899 Doi: 10.1002/hep.23068 [OPEN ACCESS]
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** Halilbasic, E; Fiorotto, R; Fickert, P; Marschall, HU; Moustafa, T; Spirli, C; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Langner, C; Maitra, U; Denk, H; Hofmann, AF; Strazzabosco, M; Trauner, M Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
Hepatology. 2009; 49(6):1972-1981 Doi: 10.1002/hep.22891 [OPEN ACCESS]
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** Jahnel, J; Fickert, P; Langner, C; Högenauer, C; Silbert, D; Gumhold, J; Fuchsbichler, A; Trauner, M Impact of experimental colitis on hepatobiliary transporter expression and bile duct injury in mice.
Liver Int. 2009; 29(9):1316-1325 Doi: 10.1111/j.1478-3231.2009.02044.x
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** Loebermann, M; Sombetzki, M; Langner, C; Fuchsbichler, A; Gumhold, J; Silbert, D; Riebold, D; Holtfreter, M; Fickert, P; Nizze, H; Trauner, M; Reisinger, EC Imbalance of pro- and antifibrogenic genes and bile duct injury in murine Schistosoma mansoni infection-induced liver fibrosis.
Trop Med Int Health. 2009; 14(11):1418-1425 Doi: 10.1111/j.1365-3156.2009.02387.x [OPEN ACCESS]
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Abstract (Zeitschrift)

** Jahnel, J; Claudel, T; Baghdasaryan, A; Langner, C; Fickert, P; Trauner, M; Hauer, AC; Silbert, A; Gumhold, J; Fuchsbichler, A PHOSPHOLIPIDS AND COLITIS: IMPACT OF NUTRITIONAL AND BILIARY LACK OF PHOSPHOLIPIDS IN A COLITIS MOUSE MODEL
ACTA PAEDIAT. 2009; 98: 29-30.-50th Annual Meeting of the European Society for Paediatric Research ; October 9-12, 2009 ; Hamburg, Germany. [Oral Communication]
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Lundasen, T; Gustafsson, U; Sahlin, S; Trauner, M STIMULATION OF HEPATOBILIARY DETOXIFICATION AND TRANSPORT SYSTEMS IN HUMAN LIVER BY COMBINED TREATMENT WITH RIFAMPICIN AND URSODEOXYCHOLIC ACID
J HEPATOL. 2009; 50: 675-Vienna, Austria. Doi: 10.1016/S0168-8278(09)60677-2 [Poster]
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Originalarbeit (Konferenzband)

** Halilbasic, E; Fickert, P; Fiorotto, R; Marschall, HU; Moustafa, T; Fuchsbichler, A; Gumhold, J; Silbert, D; Langner, C; Maitra, U; Denk, H; Strazzabosco, M; Trauner, M Side-chain modification as critical determinant of the therapeutic properties of 24-norursodeoxycholic acid in Mdr2 (Abcb4) knockout mice
FALK SYMP. 2009; 165: 157-162. [Oral Communication]
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** Trauner, M; Fickert, P; Moustafa, T; Fuchsbichler, A; Claudel, T; Halilbasic, E; Kratky, D; Denk, H Potential role of ursodeoxycholic acid and its side-chain modified derivatives in the treatment of non-alcoholic fatty liver disease and associated atherosclerosis
FALK SYMP. 2009; 165: 151-156. [Oral Communication]
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Kommentar

** Fickert, P; Trauner, M When lightning strikes twice: the plot thickens for a dual role of the anion exchanger 2 (AE2/SLC4A2) in the pathogenesis and treatment of primary biliary cirrhosis.
J Hepatol. 2009; 50(3):633-635 Doi: 10.1016/j.jhep.2008.12.006
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2008

Originalarbeit (Zeitschrift)

** Baghdasaryan, A; Fickert, P; Fuchsbichler, A; Silbert, D; Gumhold, J; Hörl, G; Langner, C; Moustafa, T; Halilbasic, E; Claudel, T; Trauner, M Role of hepatic phospholipids in development of liver injury in Mdr2 (Abcb4) knockout mice.
Liver Int. 2008; 28(7):948-958 Doi: 10.1111/j.1478-3231.2008.01758.x
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Übersichtsarbeit

** Trauner, M; Fickert, P; Halilbasic, E; Moustafa, T Lessons from the toxic bile concept for the pathogenesis and treatment of cholestatic liver diseases.
Wien Med Wochenschr. 2008; 158(19-20):542-548 Doi: 10.1007/s10354-008-0592-1
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Abstract (Zeitschrift)

** Baghdasaryan, A; Kosters, A; Claudel, T; Fuchsbichler, A; Gumhold, J; Silbert, D; Leski, K; Fickert, P; Karpen, SJ; Trauner, M Curcumin improves liver injury and biliary fibrosis in MDR2 (ABCB4) knockout mice by inducing anti-oxidative response, but not via modification of bile acid transport/metabolism
J HEPATOL. 2008; 48: S171-S171.-EASL Annual Meeting; April 2008; Milan Italy. Doi: 10.1016/S0168-8278(08)60450-X [Poster]
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** Fickert, P; Moustafa, T; Fuchsbichler, A; Claudel, T; Halilbasic, E; Zatloukal, K; Denk, H; Trauner, M Differential effects of nor UDCA and UDCA in the treatment of fatty liver and arteriosclerosis in western chow-fed ApoE knock out mice
J HEPATOL. 2008; 48: S42-S42.-Annual Meeting, EASL; April 2008; Milann, Italy. Doi: 10.1016/S0168-8278(08)60100-2 [Oral Communication]
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** Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Halilbasic, E; Trauner, MH LOSS OF FXR ATTENUATES SCLEROSING CHOLANGITIS AND BILIARY FIBROSIS IN MDR2(-/-) AND FXR(-/-) DOUBLE KNOCKOUT MICE
HEPATOLOGY. 2008; 48(4):777--59th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; OCT 31-NOV 04, 2008; San Francisco, CA. [Poster]
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** Moustafa, T; Halilbasic, E; Fickert, P; Fuchsbichler, A; Gumhold, J; Silbert, D; Denk, H; Trauner, M Side chain modified bile acids modulate endoplasmic reticulum stress in Mdr2(-/-) mice in vivo and bile duct epithelial cells in vitro
J HEPATOL. 2008; 48: S54-S55.-EASL Annula Meeting; April 2008; Milan Italy. Doi: 10.1016/S0168-8278(08)60127-0 [Oral Communication]
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** Sombetzki, M; Fickert, P; Loebermann, M; Holtfreter, M; Fuchsbichler, A; Gumhold, J; Silbert, D; Langner, C; Reisinger, EC; Trauner, M 24-nor-ursodeoxycholic acid as novel therapeutic strategy for inflammation-induced liver fibrosis in a murine model of schistosoma mansoni infection
J HEPATOL. 2008; 48: S21-S22.-Annual Meeting, EASL; April 2008; Mailand, Italien. Doi: 10.1016/S0168-8278(08)60052-5 [Oral Communication]
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2007

Originalarbeit (Zeitschrift)

** Fickert, P; Stöger, U; Fuchsbichler, A; Moustafa, T; Marschall, HU; Weiglein, AH; Tsybrovskyy, O; Jaeschke, H; Zatloukal, K; Denk, H; Trauner, M A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis.
Am J Pathol. 2007; 171(2):525-536 Doi: 10.2353/ajpath.2007.061133 [OPEN ACCESS]
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** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, JS; Zatloukal, K; Denk, H; Jaeschke, H; Trauner, M Hepatobiliary transporter expression in intercellular adhesion molecule 1 knockout and Fas receptor-deficient mice after common bile duct ligation is independent of the degree of inflammation and oxidative stress.
Drug Metab Dispos. 2007; 35(9):1694-1699 Doi: 10.1124/dmd.107.015610 [OPEN ACCESS]
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** Zollner, G; Fickert, P; Trauner, M Cholestasis
WIEN KLIN WOCHENSCHR. 2007; 119: 125-140. Doi: 10.1007/s11812-007-0029-6
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** Zollner, G; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis.
Liver Int. 2007; 27(7):920-929 Doi: 10.1111/j.1478-3231.2007.01506.x
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Übersichtsarbeit

** Fickert, P; Moustafa, T; Trauner, M Primary sclerosing cholangitis--the arteriosclerosis of the bile duct?
Lipids Health Dis. 2007; 6(2):3-3 Doi: 10.1186/1476-511X-6-3 [OPEN ACCESS]
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** Trauner, M; Fickert, P; Wagner, M MDR3 (ABCB4) defects: a paradigm for the genetics of adult cholestatic syndromes.
Semin Liver Dis. 2007; 27(1):77-98 Doi: 10.1055/s-2006-960172 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Halilbasic, E; Fickert, P; Fuchbichler, A; Langner, C; Gumhold, J; Silbert, D; Maitra, U; Zatloukal, K; Denk, H; Trauner, M Taurine-conjugation critically determines the therapeutic effectiveness of 24-nor-ursodeoxycholic acid (norUDCA) in the treatment of sclerosing cholangitis in Mdr2 (ABCB4) knockout mice
J HEPATOL. 2007; 46: S51-S51.-EASL; April 11-15, 2007; Doi: 10.1016/S0168-8278(07)61714-0 [Oral Communication]
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** Halilbasic, E; Fickert, P; Fuchsbichler, A; Moustafa, T; Stoeger, U; Ueno, Y; Denk, H; Trauner, M TNF alpha and LPS but not bile acids play a key role in the induction of reactive phenotype in bile duct epithelial cells in vitro
J HEPATOL. 2007; 46: S121-S121.-EASL; April 11-15, 2007; Barcelona/Spain. Doi: 10.1016/S0168-8278(07)61905-9 [Poster]
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** Jahnel, J; Wagner, M; Langner, C; Hoegenauer, C; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M Impact of colitis on bile secretion and hepatobiliary transporter expression in mice possible implications for pathogenesis of sclerosing cholangitis
J HEPATOL. 2007; 46: S122-S122. Doi: 10.1016/S0168-8278(07)61907-2 [Poster]
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** Maitz, S; Wimmer, R; Rust, C; Denk, H; Invernizzi, P; Ferdinandusse, S; Wanders, RJ; Fuchsbichler, A; Fickert, P; Trauner, M; Hofmann, AF; Beuers, U Taurine conjugation is essential for anticholestatic action of norursodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver
HEPATOLOGY. 2007; 46(4):338A-339A.-AASLD; NOV 2-6, 2007; Boston, USA. [Poster]
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** Moustafa, T; Fickert, P; Vesely, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Guelly, C; Trauner, M Retention of toxic bile acids activate the mTOR, p70S6k/rps6 signaling pathway in mouse models of cholestatic liver injury
J HEPATOL. 2007; 46: S23-S23. Doi: 10.1016/S0168-8278(07)61646-8 [Oral Communication]
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** Wagner, M; Moustafa, T; Fickert, P; Zollner, G; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Absence of FXR protects mice from bile-infarcts in biliary obstruction by reduction of bile acid-independent bile flow: Implications for targeting FXR in treatment of cholestasis?
J HEPATOL. 2007; 46: S5-S5.-42th Annual Meeting, European Association for the Study of the Liver; April, 11-15, 2007; Barcelona, Spain. Doi: 10.1016/S0168-8278(07)61603-1 [Oral Communication]
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** Zollner, G; Caligiuri, A; Fickert, P; Wagner, M; Silbert, D; Pinzani, M; Trauner, M Expression of bile acid transport and detoxification systems and their regulatory nuclear receptors in human hepatic stellate cells
J HEPATOL. 2007; 46: S135-S135.-42th Annual Meeting, European Association for the Study of the Liver ; April 11-15, 2007; Barcelona, Spain. Doi: 10.1016/S0168-8278(07)61944-8 [Poster]
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2006

Originalarbeit (Zeitschrift)

** Fickert, P; Fuchsbichler, A; Marschall, HU; Wagner, M; Zollner, G; Krause, R; Zatloukal, K; Jaeschke, H; Denk, H; Trauner, M Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.
Am J Pathol. 2006; 168(2):410-422 Doi: 10.2353/ajpath.2006.050404 [OPEN ACCESS]
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** Fickert, P; Wagner, M; Marschall, HU; Fuchsbichler, A; Zollner, G; Tsybrovskyy, O; Zatloukal, K; Liu, J; Waalkes, MP; Cover, C; Denk, H; Hofmann, AF; Jaeschke, H; Trauner, M 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Gastroenterology. 2006; 130(2):465-481 Doi: 10.1053/j.gastro.2005.10.018
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** Marschall, HU; Wagner, M; Bodin, K; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Sjövall, J; Trauner, M Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids.
J Lipid Res. 2006; 47(3):582-592 Doi: 10.1194/jlr.M500427-JLR200 [OPEN ACCESS]
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** Rust, C; Bauchmuller, K; Bernt, C; Vennegeerts, T; Fickert, P; Fuchsbichler, A; Beuers, U Sulfasalazine reduces bile acid induced apoptosis in human hepatoma cells and perfused rat livers.
GUT. 2006; 55(5): 719-727. Doi: 10.1136/gut.2005.077461 [OPEN ACCESS]
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** Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Halilbasic, E; Denk, H; Marschall, HU; Trauner, M Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Am J Physiol Gastrointest Liver Physiol. 2006; 290(5):G923-G932 Doi: 10.1152/ajpgi.00490.2005 [OPEN ACCESS]
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Übersichtsarbeit

** Geier, A; Fickert, P; Trauner, M Mechanisms of disease: mechanisms and clinical implications of cholestasis in sepsis.
Nat Clin Pract Gastroenterol Hepatol. 2006; 3(10): 574-585. Doi: 10.1038/ncpgasthep0602
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Abstract (Zeitschrift)

** Moustafa, T; Fickert, P; Guelly, C; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M Transcriptional profiling of Mdr2 knockout (Mdr2-/-) mice treated with nor-UDCA reveals global anti-inflammatory and anti-fibrotic effects
J HEPATOL. 2006; 44: S42-S42.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(06)80095-4 [Poster]
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** Moustafa, T; Fickert, P; Guelly, C; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M 24-nor-ursodeoxycholic acid abolishes enhanced cellular proliferation in Mdr2 (abcb4) knockout mice by modulation of mTOR, p70s6k and rps6 signaling
HEPATOLOGY. 44(4):602A-603A. [Poster]
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** Moustafa, T; Fickert, P; Prokesch, A; Wagner, M; Fuchsbichler, A; Silbert, D; Gumhold, J; Denk, H; Trajanoski, Z; Trauner, M Common bile-duct-ligation of FXR knockout mice results in severe hepatic steatosis due to enhancement in lipogenic gene expression
J HEPATOL. 44: S28-S28.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(06)80063-2 [Poster]
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** Stoger, U; Fickert, P; Fuchsbichler, A; Moustafa, T; Gumhold, J; Silbert, D; Zatlouka, K; Denk, H; Trauner, M 3.5-diethoxycarbonyl-1.4-dihydrocollidine (DDC) feeding induces cholestasis, chronic inflammatory bile duct damage and biliary fibrosis in mice
J HEPATOL. 44: S123-S124.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(06)80321-1 [Poster]
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** Zollner, G; Fuchsbichler, A; Fickert, P; Denk, H; Trauner, M Alterations of hepatic bilirubin and phospholipid export pumps MRP2 and MDR3 in patients with drug-induced liver injury
HEPATOLOGY. 44(4):381A-381A. [Poster]
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** Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Helmut, D; Marschall, HU; Trauner, M Role of nuclear bile acid receptor FXR in regulation of bile acid detoxification and organic solute transporter (OST-alpha/beta) expression in bile acid-fed mice
J HEPATOL. 44: S124-S124.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(06)80322-3 [Poster]
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2005

Originalarbeit (Zeitschrift)

** Cover, C; Fickert, P; Knight, TR; Fuchsbichler, A; Farhood, A; Trauner, M; Jaeschke, H Pathophysiological role of poly(ADP-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice.
Toxicol Sci. 2005; 84(1):201-208 Doi: 10.1093/toxsci/kfi065 [OPEN ACCESS]
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Marschall, HU; Zatloukal, K; Denk, H Oncosis represents the main type of cell death in mouse models of cholestasis.
J Hepatol. 2005; 42(3):378-385 Doi: 10.1016/j.jhep.2004.10.016
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** Geier, A; Zollner, G; Dietrich, CG; Wagner, M; Fickert, P; Denk, H; van Rooijen, N; Matern, S; Gartung, C; Trauner, M Cytokine-independent repression of rodent Ntcp in obstructive cholestasis.
Hepatology. 2005; 41(3):470-477 Doi: 10.1002/hep.20594 [OPEN ACCESS]
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Diczfalusy, U; Gumhold, J; Silbert, D; Fuchsbichler, A; Benthin, L; Grundström, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans.
Gastroenterology. 2005; 129(2):476-485 Doi: 10.1016/j.gastro.2005.05.009
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** Popov, Y; Patsenker, E; Fickert, P; Trauner, M; Schuppan, D Mdr2 (Abcb4)-/- mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro- and antifibrogenic genes.
J HEPATOL. 2005; 43(6): 1045-1054. Doi: 10.1016/j.jhep.2005.06.025
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** Rust, C; Bauchmuller, K; Fickert, P; Fuchsbichler, A; Beuers, U Phosphatidylinositol 3-kinase-dependent signaling modulates taurochenodeoxycholic acid-induced liver injury and cholestasis in perfused rat livers.
AMER J PHYSIOL-GASTROINTEST L. 2005; 289(1): G88-G94. Doi: 10.1152/ajpgi.00450.2004 [OPEN ACCESS]
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** Stadlbauer, V; Fickert, P; Lackner, C; Schmerlaib, J; Krisper, P; Trauner, M; Stauber, RE Hepatotoxicity of NONI juice: report of two cases.
World J Gastroenterol. 2005; 11(30):4758-4760 Doi: 10.3748/wjg.v11.i30.4758 (- Case Report) [OPEN ACCESS]
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** Wagner, M; Halilbasic, E; Marschall, HU; Zollner, G; Fickert, P; Langner, C; Zatloukal, K; Denk, H; Trauner, M CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
Hepatology. 2005; 42(2):420-430 Doi: 10.1002/hep.20784 [OPEN ACCESS]
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** Zollner, G; Wagner, M; Fickert, P; Geier, A; Fuchsbichler, A; Silbert, D; Gumhold, J; Zatloukal, K; Kaser, A; Tilg, H; Denk, H; Trauner, M Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver.
Am J Physiol Gastrointest Liver Physiol. 2005; 289(5):G798-G805 Doi: 10.1152/ajpgi.00319.2004 [OPEN ACCESS]
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** Zollner, G; Wagner, M; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Hepatobiliary transporter expression in human hepatocellular carcinoma.
Liver Int. 2005; 25(2):367-379 Doi: 10.1111/j.1478-3231.2005.01033.x
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Übersichtsarbeit

** Trauner, M; Wagner, M; Fickert, P; Zollner, G Molecular regulation of hepatobiliary transport systems: clinical implications for understanding and treating cholestasis.
J Clin Gastroenterol. 2005; 39(4 Suppl 2):S111-S124 Doi: 10.1097/01.mcg.0000155551.37266.26 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Krause, R; Zatloukal, K; Marschall, HU; Jaeschke, H; Denk, H; Trauner, M Lithocholic acid feeding induces biliary obstruction and destructive cholangitis in mice
J HEPATOL. 2005; 42: 113-113.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
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** Fickert, P; Wagner, M; Marshall, HU; Fuchsbichler, A; Zollner, G; Zatloukal, K; Liu, J; Waalkes, MP; Cover, C; Denk, H; Hofmann, AF; Jaeschke, H; Trauner, M 24-norursodeoxycholic acid as novel therapeutic approach to sclerosing cholangitis in Mdr2 (ABCB4) knockout mice
HEPATOLOGY. 2005; 42: -56th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 11-15, 2005; San Francisco, CA.
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** Geier, A; Zollner, G; Dietrich, CG; Wagner, M; Fickert, P; Denk, H; van Rooijen, N; Matern, S; Gartung, C; Trauner, M Cytokine-independent repression of rodent Ntcp in obstructive cholestasis
J HEPATOL. 2005; 42: 114-114.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
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** Janig, E; Fuchsbichler, A; Fickert, P; Trauner, M; Denk, H; Zatloukal, K Clusterin: A novel stress marker in biliary disease models
HEPATOLOGY. 2005; 42 (4): 413-414.-56th Annual Meeting of the American Association for the Study of Liver Diseases; NOV 11-15, 2005; San Francisco, CA.
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in human liver
GASTROENTEROLOGY. 2005; 128: A755-A755.
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** Marschall, HU; Wagnr, M; Bodin, K; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Sjovall, J; Trauner, M Fxr -/- mice adapt to obstructive cholestasis by enhanced phase I detoxification and renal elimination of bile acids
J HEPATOL. 2005; 42: 114-115.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
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** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, J; Zatloukal, K; Jaeschke, H; Deck, H; Trauner, M Role of inflammation for hepatobiliary transporter expression in ICAM-/- and lpr mice after common bile duct ligation
GASTROENTEROLOGY. 2005; 128: A89-A89.
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** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, JS; Zatloukal, K; Denk, H; Jaeschke, H; Trauner, M Alterations of hepatobiliary transporter expression in response to common bile duct ligation in mice are independent of ICAM-1 and FAS-receptor expression
J HEPATOL. 2005; 42: 115-115.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
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** Zollner, G; Wagner, M; Fickert, P; Gumhold, J; Silbert, D; Marschall, HU; Denk, H; Trauner, M Expression of key bile acid detoxification enzymes and the alternative bile acid export pump MRP4 in primary biliary cirrhosis
J HEPATOL. 2005; 42: 240-240.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
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** Zollner, G; Wagner, M; Fickert, P; Gumhold, J; Silbert, D; Marschall, HU; Denk, H; Trauner, M Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis
GASTROENTEROLOGY. 2005; 128: A691-A691.
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2004

Originalarbeit (Zeitschrift)

** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Lammert, F; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Gastroenterology. 2004; 127(1):261-274 Doi: 10.1053/j.gastro.2004.04.009
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** Lammert, F; Wang, DQ; Hillebrandt, S; Geier, A; Fickert, P; Trauner, M; Matern, S; Paigen, B; Carey, MC Spontaneous cholecysto- and hepatolithiasis in Mdr2-/- mice: a model for low phospholipid-associated cholelithiasis.
Hepatology. 2004; 39(1):117-128 Doi: 10.1002/hep.20022 [OPEN ACCESS]
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** Wenzl, HH; Hinterleitner, TA; Aichbichler, BW; Fickert, P; Petritsch, W Mycophenolate mofetil for Crohn's disease: short-term efficacy and long-term outcome.
Aliment Pharmacol Ther. 2004; 19(4):427-434 Doi: 10.1111/j.1365-2036.2004.01856.x [OPEN ACCESS]
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Kurzbericht/Letter

** Trauner, M; Fickert, P; Lammert, F; Marschall, HU ABCB4 gene mutations and primary sclerosing cholangitis - Reply
GASTROENTEROLOGY. 2004; 126: 1222-1223. Doi: 10.1053/j.gastro.2004.02.043
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** Wenzl, HH; Högenauer, C; Fickert, P; Petritsch, W Thioguanine-induced symptomatic thrombocytopenia.
AMER J GASTROENTEROL. 2004; 99(6): 1195-1195. Doi: 10.1111/j.1572-0241.2004.30292.x (- Case Report)
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Übersichtsarbeit

** Zatloukal, K; Stumptner, C; Fuchsbichler, A; Fickert, P; Lackner, C; Trauner, M; Denk, H The keratin cytoskeleton in liver diseases.
J Pathol. 2004; 204(4):367-376 Doi: 10.1002/path.1649 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Biliary leakage of fluorescent bile acids in MDR2 knockout mice: Evidence for a critical role of bile duct leakage in the pathogenesis of sclerosing cholangitis
J HEPATOL. 2004; 40: 91-91.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90295-4
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** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Bile acids regurgitation from leaky bile ducts causes sclerosing cholangitis in Mdr2 knockout mice
GASTROENTEROLOGY. 2004; 126: A663-A663.
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Marschall, HU; Zartloukal, K; Denk, H; Zsengeller, Z; Szabo, C Oncosis represents the main type of cell death in mouse models of cholestasis: evidence for a critical role of poly(ADP-ribose) polymerase (PARP) activation in bile acid-induced hepatocytes death
FASEB J. 2004; 18: A558-A558.-Experimental Biology 2004 Meeting; APR 17-21, 2004; Washington, DC.
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** Knight, T; Fickert, P; Fuchsbichler, A; Trauner, M; Jaeschke, H Pathophysiological role of poly(adenosine 5'-diphosphate-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice.
HEPATOLOGY. 2004; 40: 650A-650A.-55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); OCT 29-NOV 02, 2004; Boston, MA.
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Sahlin, S; Einarsson, C; Trauner, M Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
GASTROENTEROLOGY. 2004; 126: A746-A746.
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumholdt, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Sahlin, S; Einarsson, C; Trauner, M Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
J HEPATOL. 2004; 40: 93-93.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90303-0
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** Rust, C; Bauchmuller, K; Fickert, P; Fuchsbichler, A; Beuers, U Phosphatidylinositol 3-kinase acid - Dependent signaling modulates taurochenodeoxycholic acid-induced liver injury and cholestasis in perfused rat livers.
HEPATOLOGY 2004 40: 568A-568A.
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** Wagner, M; Fickert, P; Marschall, HU; Zollner, G; Silbert, D; Fuchsbichler, A; Gumhold, J; Schuetz, JD; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M Alternative exretory routes for accumulating bile acids via adaptive renal ABC transporter expression in common bile duct-ligated (CBDL) mice
GASTROENTEROLOGY. 2004; 126: A129-A130.
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Gu, GL; Marschall, HU; Denk, H; Trauner, M Role of adaptive hepatobiliary transporter expression and regulation of bile acid synthetic enzymes in MDR2-/- mice: A model for chronic cholestatic liver disease due to sclerosing cholangitis
J HEPATOL. 2004; 40: 163-163.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90557-0
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Fuchsbichler, A; Gumhold, J; Schuetz, JD; Gonzalez, FJ; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Adaptive renal ABC transporter expression in common bile duct-ligated mice
J HEPATOL. 2004; 40: 26-26.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90073-6
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Hepatic and renal ABC transporter expression in mice depends on gender and changes in pregnancy
GASTROENTEROLOGY. 2004; 126: A130-A130.
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Gender and pregnancy affect hepatic and renal ABC transporter expression in mice
J HEPATOL. 2004; 40: 94-94.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90307-8
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** Wagner, M; Halilbasic, E; Fickert, P; Zollner, G; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Denk, H; Trauner, M Nuclear receptor (PXR, CAR) agonists induce adaptive hepatic transporter and enzyme expression in mouse liver
J HEPATOL. 2004; 40: 25-25.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90069-4
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** Wagner, M; Halilbasic, E; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Xenobiotic nuclear receptor (PXR, CAR) agonists coordinately stimulate a spectrum of detoxification enzymes and transport systems involved in the adaptive response to cholestasis in vivo.
HEPATOLOGY. 2004; 40: 489A-489A.-55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); OCT 29-NOV 02, 2004; Boston, MA.
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** Zollner, G; Halilbasic, E; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Differential effects of ursodeoxycholic acid (UDCA) and cholic acid (CA) on hepatic and renal expression of MRP4 and MRP6, two novel abc transporters, in mice
J HEPATOL. 2004; 40: 25-25. Doi: 10.1016/S0168-8278(04)90070-0
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** Zollner, G; Halilbasic, E; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Cholic acid (CA) and ursodeoxycholic acid (UDCA) exert different effects on hepatic and renal expression of Mrp4 and Mrp6, two novel ABC transporters
GASTROENTEROLOGY. 2004; 126: A16-A16.
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** Zollner, G; Wagner, M; Fickert, P; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Guo, GL; Marschall, HU; Denk, H; Trauner, M Mdr2(-/-) mice with sclerosing cholangitis: A model of chronic cholestasis to study the role of the adaptive response of hepatobiliary transport systems and bile acid synthetic enzymes
GASTROENTEROLOGY. 2004; 126: A751-A751.
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2003

Originalarbeit (Zeitschrift)

** Fickert, P; Trauner, M; Fuchsbichler, A; Stumptner, C; Zatloukal, K; Denk, H Mallory body formation in primary biliary cirrhosis is associated with increased amounts and abnormal phosphorylation and ubiquitination of cytokeratins.
J Hepatol. 2003; 38(4):387-394 Doi: 10.1016/S0168-8278(02)00439-7
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Tsybrovskyy, O; Zatloukal, K; Guo, GL; Schuetz, JD; Gonzalez, FJ; Marschall, HU; Denk, H; Trauner, M Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice.
Gastroenterology. 2003; 125(3):825-838 Doi: 10.1016/S0016-5085(03)01068-0
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** Wagner, M; Kaufmann, P; Fickert, P; Trauner, M; Lackner, C; Stauber, RE Successful conservative management of acute hepatic failure following exertional heatstroke.
Eur J Gastroenterol Hepatol. 2003; 15(10):1135-1139 Doi: 10.1097/01.meg.0000085465.12407.32 (- Case Report)
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** Zollner, G; Fickert, P; Fuchsbichler, A; Silbert, D; Wagner, M; Arbeiter, S; Gonzalez, FJ; Marschall, HU; Zatloukal, K; Denk, H; Trauner, M Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine.
J Hepatol. 2003; 39(4):480-488 Doi: 10.1016/S0168-8278(03)00228-9
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Marschall, HU; Zatloukal, K; Denk, H; Trauner, M Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.
J Hepatol. 2003; 38(6):717-727 Doi: 10.1016/S0168-8278(03)00096-5
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Abstract (Zeitschrift)

** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Zenz, R; Zsengeller, Z; Szabo, C; Denk, H Inhibition of poly(ADP-ribose) polymerase (PARP) protects mice from cholestatic liver injury.
HEPATOLOGY 2003 38: 576A-576A.
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** Wagner, M; Fickert, P; Fuchsbichler, A; Silbert, D; Gumhold, J; Zollner, G; Zatloukal, K; Marschall, HU; Schuetz, JD; Gonzalez, FJ; Denk, H; Trauner, M Hepatic and renal ABC transporter expression as critical determinants of ursodeoxycholic acid-induced bile infarcts in bile duct-ligated mice.
HEPATOLOGY 2003 38: 688A-689A.
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Marschall, HU; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M The role of the bile acid receptor FXR in determining ATP-binding cassette (ABC) transporter expression and liver injury in common bile duct ligated (CBDL) mice
J HEPATOL 2003 38: 190-190. Doi: 10.1016/S0168-8278(03)80031-4
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Tsybrovskyy, O; Gonzalez, FJ; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Role of nuclear bile acid receptor, FXR, in determining ATP-binding cassette (ABC) transporter expression and cholestatic liver injury in common bile duct-ligated mice
GASTROENTEROLOGY 2003 124: A697-A698. Doi: 10.1016/S0016-5085(03)83527-8
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** Zatloukal, K; Stumptner, C; Fuchsbichler, A; Fickert, P; Trauner, M; Denk, H The role of keratin in steatohepatitis.
HEPATOLOGY 2003 38: 501A-501A.
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Guo, G; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M Role of nuclear bile salt receptors Fxr and Pxr in mediating adaptive hepatobiliary transporter response to cholic acid (CA) in mouse liver
GASTROENTEROLOGY 2003 124: A59-A59. Doi: 10.1016/S0016-5085(03)80292-5
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Zatloukal, K; Denk, H; Trauner, M Regulation of the Na+/taurocholate cotransporter Ntcp via short heterodimer partner (SHP)-dependent or SHP-independent mechanims depends on the type of cholestatic injury
GASTROENTEROLOGY 2003 124: A730-A730. Doi: 10.1016/S0016-5085(03)83688-0
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Zatloukal, K; Denk, H; Trauner, M Role of short heterodimer partner (SHP) -dependent and -independent pathways for regulation of Na+/taurocholate cotransporter (NTCP) expression in cholestatic mouse models.
J HEPATOL. 2003; 38(2):9-10.-38th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; MAR 29-APR 01, 2003; ISTANBUL, TURKEY. Doi: 10.1016/S0168-8278(03)80442-7
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** Zollner, G; Fickert, P; Wagner, M; Fuchsbichler, A; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M Induction of intestinal multidrug resistance-associated proteins 2 and 3 (Mrp2, Mrp3) by cholic acid (CA) and ursodeoxycholic acid (UDCA) in mice.
HEPATOLOGY 2003 38: 689A-689A.
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2002

Originalarbeit (Zeitschrift)

** Fickert, P; Trauner, M; Fuchsbichler, A; Stumptner, C; Zatloukal, K; Denk, H Bile acid-induced Mallory body formation in drug-primed mouse liver.
Am J Pathol. 2002; 161(6):2019-2026 Doi: 10.1016/S0002-9440(10)64480-X [OPEN ACCESS]
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** Fickert, P; Trauner, M; Fuchsbichler, A; Stumptner, C; Zatloukal, K; Denk, H Cytokeratins as targets for bile acid-induced toxicity.
Am J Pathol. 2002; 160(2):491-499 Doi: 10.1016/S0002-9440(10)64868-7 [OPEN ACCESS]
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** Fickert, P; Zollner, G; Fuchsbichler, A; Stumptner, C; Weiglein, AH; Lammert, F; Marschall, HU; Tsybrovskyy, O; Zatloukal, K; Denk, H; Trauner, M Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles.
Gastroenterology. 2002; 123(4):1238-1251 Doi: 10.1053/gast.2002.35948
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Stumptner, C; Zatloukal, K; Denk, H; Trauner, M Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice.
Am J Physiol Gastrointest Liver Physiol. 2002; 282(1):G184-G191 Doi: 10.1152/ajpgi.00215.2001 [OPEN ACCESS]
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Kurzbericht/Letter

** Hegenbarth, K; Fickert, P; Aschauer, M; Horina, JH; Stauber, RE; Trauner, M Successful management of acute portal vein thrombosis by low molecular weight heparin and oral anticoagulation.
Am J Gastroenterol. 2002; 97(6):1567-1568 Doi: 10.1111/j.1572-0241.2002.05750.x (- Case Report)
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Abstract (Zeitschrift)

** Fickert, P; Trauner, M; Fuchsbichler, A; Stumptner, C; Neuberger, J; Zatloukal, K; Denk, H Abnormal expression and phosphorylation of cytokeratins in primary biliary cirrhosis (PBC).
J HEPATOL. 2002; 36(S1):141-141. Doi: 10.1016/S0168-8278(02)80506-2
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** Fickert, P; Zollner, G; Silbert, D; Fuchsbichler, A; Arbeiter, S; Gonzalez, F; Denk, H; Trauner, M Adaptive hepatic and renal transporter regulation in cholic acid (CA)-fed mice: Role of nuclear bile acid receptor (FXR).
HEPATOLOGY 2002 36: 454A-454A.
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** Zollner, G; Fickert, P; Arbeiter, S; Silbert, D; Fuchsbichler, A; Gonzalez, F; Zatloukal, K; Denk, H; Trauner, M Ursodeoxycholic acid (UDCA) feeding induces adaptive hepatic and renal ABC-transporter expression in mice.
HEPATOLOGY 2002 36: 454A-454A.
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Stumptner, C; Neuberger, J; Zatloukal, K; Denk, H; Trauner, M Alterations of hepatobiliary transporter expression in primary biliary cirrhosis (PBC)
J HEPATOL 2002 36: 28-29. Doi: 10.1016/S0168-8278(02)80086-1
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Messenger RNA expression of nuclear, orphan receptors and hepatocyte nuclear factor 1 alpha (HNF-1 alpha) in inflammation-associated cholestasis (IC) and primary biliary cirrhosis
HEPATOLOGY 2002 36: 454A-454A.
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2001

Originalarbeit (Zeitschrift)

** Ferenci, P; Stauber, R; Steindl-Munda, P; Gschwantler, M; Fickert, P; Datz, C; Müller, C; Hackl, F; Rainer, W; Watkins-Riedel, T; Lin, W; Krejs, GJ; Gangl, A; Austrian Hepatitis Study Group Treatment of patients with chronic hepatitis C not responding to interferon with high-dose interferon alpha with or without ribavirin: final results of a prospective randomized trial. Austrian Hepatitis Study Group.
Eur J Gastroenterol Hepatol. 2001; 13(6):699-705 Doi: 10.1097/00042737-200106000-00014
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** Fickert, P; Zollner, G; Fuchsbichler, A; Stumptner, C; Pojer, C; Zenz, R; Lammert, F; Stieger, B; Meier, PJ; Zatloukal, K; Denk, H; Trauner, M Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver.
Gastroenterology. 2001; 121(1):170-183 Doi: 10.1053/gast.2001.25542
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** Zollner, G; Fickert, P; Zenz, R; Fuchsbichler, A; Stumptner, C; Kenner, L; Ferenci, P; Stauber, RE; Krejs, GJ; Denk, H; Zatloukal, K; Trauner, M Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases.
Hepatology. 2001; 33(3):633-646 Doi: 10.1053/jhep.2001.22646 [OPEN ACCESS]
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Kurzbericht/Letter

** Hegenbarth, K; Maurer, U; Kroisel, PM; Fickert, P; Trauner, M; Stauber, RE No evidence for mutagenic effects of ribavirin: report of two normal pregnancies.
Am J Gastroenterol. 2001; 96(7):2286-2287 Doi: 10.1111/j.1572-0241.2001.03997.x (- Case Report)
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Übersichtsarbeit

** Trauner, M; Fickert, P; Zollner, G Genetic disorders and molecular mechanisms in cholestatic liver disease--a clinical approach.
Semin Gastrointest Dis. 2001; 12(2):66-88 (- Case Report)
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Abstract (Zeitschrift)

** Fickert, P; Fuchsbichler, A; Zollner, G; Stumptner, C; Weiglein, A; Zatloukal, K; Denk, H; Trauner, M Mdr2-p-glycoprotein-deficient (Mdr2-/-) mouse - A new model for primary sclerosing cholangitis (PSC)?
HEPATOLOGY 2001 34: 509A-509A.
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** Fickert, P; Zollner, G; Fuchsbichler, A; Stumptner, C; Lammert, F; Zaltloukal, K; Denk, H; Trauner, M Ursodeoxycholic acid (UDCA) feeding aggravates liver injury in bile duct-ligated and Mdr2 kockout mice
J HEPATOL 2001 34: 182-182.
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** Fickert, P; Zollner, G; Fuchsbichler, A; Stumptner, C; Lammert, F; Zatloukal, K; Denk, H; Trauner, M Ursodeoxycholic acid feeding aggravates liver injury in bile duct-ligated mice
GASTROENTEROLOGY 2001 120: A1-A1.
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** Zollner, G; Fickert, P; Fuchsbichler, A; Stumptner, C; Denk, H; Zatloukal, K; Ferenci, P; Trauner, M Expression of multidrug resistance P-glycoproteins (MDRs) and multidrug resistance-associated proteins (MRPs) in Wilson disease (WD)
J HEPATOL 2001 34: 188-188.
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** Zollner, G; Fickert, P; Fuchsbichler, A; Stumptner, C; Denk, H; Zatloukal, K; Trauner, M Multidrug resistance P-glycoproteins (MDR) and multidrug resistance-associated proteins (MRP) are not overexpressed in human hepatocellular carcinomas (HCC).
J HEPATOL 2001 34: 189-189.
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Stumptner, C; Ott, P; Zatloukal, K; Denk, H; Trauner, M Expression of multidrug resistance p-glycoproteins (MDR), multidrug resistance-associated proteins (MRP) and bile acid transporters in human hepatocellular carcinomas (HCC).
HEPATOLOGY 2001 34: 665A-665A.
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M; Franzens, K Induction of the transcriptional repressor short heterodimer partner 1 precedes down-regulation of the Na+/taurocholate cotransporter in bile duct-ligated mice.
HEPATOLOGY 2001 34: 469A-469A.
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Kommentar

** Trauner, M; Fickert, P; Zollner, G Abnormal hepatic sinusoidal bile acid transport: new insights into the pathogenesis of cholestasis?
Gastroenterology. 2001; 120(1):321-323 Doi: 10.1053/gast.2001.21380
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2000

Originalarbeit (Zeitschrift)

** Fickert, P; Trauner, M; Hausegger, K; Tauss, J; Lackner, H; Krejs, GJ; Stauber, RE Intra-hepatic haematoma complicating transjugular intra-hepatic portosystemic shunt for Budd-Chiari syndrome associated with anti-phospholipid antibodies, aplastic anaemia and chronic hepatitis C.
Eur J Gastroenterol Hepatol. 2000; 12(7):813-816 Doi: 10.1097/00042737-200012070-00017 (- Case Report)
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** Stumptner, C; Omary, MB; Fickert, P; Denk, H; Zatloukal, K Hepatocyte cytokeratins are hyperphosphorylated at multiple sites in human alcoholic hepatitis and in a mallory body mouse model.
Am J Pathol. 2000; 156(1):77-90 Doi: 10.1016/S0002-9440(10)64708-6 [OPEN ACCESS]
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Kurzbericht/Letter

** Auner, HW; Beham-Schmid, C; Lindner, G; Fickert, P; Linkesch, W; Sill, H Successful nonsurgical treatment of primary mucosa-associated lymphoid tissue lymphoma of colon presenting with multiple polypoid lesions.
Am J Gastroenterol. 2000; 95(9):2387-2389 Doi: 10.1111/j.1572-0241.2000.02343.x (- Case Report)
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Übersichtsarbeit

** Trauner, M; Fickert, P; Stauber, RE Hepatocellular bile salt transport: lessons from cholestasis.
Can J Gastroenterol. 2000; 14 Suppl D(3):99D-104 Doi: 10.1155/2000/870929
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Abstract (Zeitschrift)

** Fickert, P; Trauner, M; Fuchsbichler, A; Zatloukal, K; Denk, H Toxic bile acids induce cytokeratin 8/18 overexpression and hyperphosphorylation in mouse liver.
GASTROENTEROLOGY 2000 118: 3726-3726. Doi: 10.1016/S0016-5085(00)86223-X
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zatloukal, K; Denk, H Cytokeratin 8/18 overexpression and hyperphosphorylation induced by toxic bile acids in mouse liver
J HEPATOL 2000 32: 76-76. Doi: 10.1016/S0168-8278(00)80623-6
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** Fickert, P; Zenz, R; Zoliner, G; Pojer, C; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Role of bile acid hydrophobicity in regulation of hepatocellular transporter expression in mice
J HEPATOL. 2000; 32(1 Su):39-39. Doi: 10.1016/S0168-8278(00)80479-1
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** Fickert, P; Zenz, R; Zollner, G; Pojer, C; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Regulation of hepatocellular transporter expression depends on bile acid hydrophobicity in mice.
GASTROENTEROLOGY 2000 118: 168-168. Doi: 10.1016/S0016-5085(00)85876-X
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** Stauber, RE; Hegenbarth, KS; Maurer, U; Kroisel, PM; Fickert, P; Trauner, M No evidence for teratogenic effects of ribavirin: Report of two cases.
HEPATOLOGY 2000 32: 1639-1639.
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** Wenzl, HH; Hinterleitner, TA; Fickert, P; Aichbichler, BW; Metzler, O; Derler, AM; Petritsch, W Low efficacy of long-term treatment with mycophenolate mofetil in patients with Crohn's disease.
GASTROENTEROLOGY 2000 118: 4214-4214. Doi: 10.1016/S0016-5085(00)85302-0
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1999

Originalarbeit (Zeitschrift)

** Ferenci, P; Stauber, R; Steindl-Munda, P; Gschwantler, M; Fickert, P; Datz, C; Müller, C; Hackl, F; Rainer, W; Watkins-Riedel, T; Lin, W Interim analysis of a randomized controlled trial of combination of ribavirin and high dose interferon-alpha in interferon nonresponders with chronic hepatitis C.
J Viral Hepat. 1999; 6 Suppl 1(7):53-58 Doi: 10.1046/j.1365-2893.1999.00005.x
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** Kessler, HH; Pierer, K; Santner, BI; Vellimedu, SK; Stelzl, E; Marth, E; Fickert, P; Stauber, RE Evaluation of molecular parameters for routine assessment of viremia in patients with chronic hepatitis C who are undergoing antiviral therapy.
J Hum Virol. 1999; 1(5):314-319
PubMed

 

Übersichtsarbeit

** Trauner, M; Fickert, P; Stauber, RE Inflammation-induced cholestasis.
J Gastroenterol Hepatol. 1999; 14(10):946-959 Doi: 10.1046/j.1440-1746.1999.01982.x [OPEN ACCESS]
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** Trauner, M; Fickert, P; Stauber, RE New molecular aspects of cholestatic liver diseases.
Z Gastroenterol. 1999; 37(7):639-647
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Abstract (Zeitschrift)

** Fickert, P; Trauner, M; Fuchsbichler, A; Kenner, L; Zatloukal, K; Denk, H Role of Kupffer cells in hepatocellular cytokeratin 8/18 expression in lipopoly-saccharide or DDC-induced hepatic injury.
HEPATOLOGY 1999 30: 552A-552A.
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zatloukal, K; Denk, H Cholestasis and bile acid feeding induce cytokeratin 8/18 expression and mallory body formation in mice.
HEPATOLOGY 1999 30: 464A-464A.
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** Stumptner, C; Zatloukal, K; Fickert, P; Denk, H P62/A170 - A novel component of Mallory Bodies associated with alcoholic hepatitis.
HEPATOLOGY 1999 30: 551A-551A.
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** Stumptner, C; Zatloukal, K; Fickert, P; Denk, H p62/A170 - A novel component of mallory bodies associated with alcoholic hepatitis.
HEPATOLOGY 1999 30: 412A-412A.
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** Trauner, M; Fickert, F; Zenz, R; Pojer, C; Fuchsbichler, A; Zollner, G; Denk, H; Zatloukal, K Role of Kupffer cells in regulation of multidrug resistance (mdr) P-glycoprotein expression in intrahepatic and obstructive cholestasis.
HEPATOLOGY 1999 30: 463A-463A.
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** Trauner, M; Zenz, R; Fickert, P; Kenner, L; Stauber, RE; Denk, H; Zatloukal, K Quantification of hepatobiliary transporter expression in liver biopsies from patients with cholestasis.
HEPATOLOGY 1999 30: 467A-467A.
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1998

Originalarbeit (Zeitschrift)

** Fickert, P; Hinterleitner, TA; Wenzl, HH; Aichbichler, BW; Petritsch, W Mycophenolate mofetil in patients with Crohn's disease.
Am J Gastroenterol. 1998; 93(12):2529-2532 Doi: 10.1111/j.1572-0241.1998.00606.x
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** Fickert, P; Trauner, M; Sill, H; Hinterleitner, TA; Stauber, RE Successful steroid treatment of idiopathic thrombocytopenic purpura after orthotopic liver transplantation for primary biliary cirrhosis.
Am J Gastroenterol. 1998; 93(10):1985-1986 Doi: 10.1111/j.1572-0241.1998.00561.x (- Case Report)
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** Heinemann, A; Wachter, CH; Fickert, P; Trauner, M; Stauber, RE Vasopressin reverses mesenteric hyperemia and vasoconstrictor hyporesponsiveness in anesthetized portal hypertensive rats.
Hepatology. 1998; 28(3):646-654 Doi: 10.1002/hep.510280307 [OPEN ACCESS]
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** Uggowitzer, M; Kugler, C; Gröll, R; Mischinger, HJ; Stacher, R; Fickert, P; Weiglein, A Sonographic evaluation of focal nodular hyperplasias (FNH) of the liver with a transpulmonary galactose-based contrast agent (Levovist).
Br J Radiol. 1998; 71(850):1026-1032 Doi: 10.1259/bjr.71.850.10211062 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Kenner, L; Stumptner, C; Trauner, M; Fickert, P; Stauber, RE; Eferl, R; Denk, H; Zatloukal, K Tau overexpression in human alcoholic liver disease.
HEPATOLOGY 1998 28: 512A-512A.
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** Kenner, L; Trauner, M; Fickert, P; Stauber, RE; Eferl, R; Denk, H; Zatloukal, K Overexpression of keratin-8 and -18 RNA associated with mallory body formation in patients with alcoholic hepatitis.
HEPATOLOGY 1998 28: 303A-303A.
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** Stauber, RE; Trauner, M; Fickert, P Soreness of mucosal membranes in patients receiving interferon-alpha plus ribavirin for treatment of chronic hepatitis C.
HEPATOLOGY 1998 28: 704A-704A.
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1997

Originalarbeit (Zeitschrift)

** Heinemann, A; Wachter, CH; Holzer, P; Fickert, P; Stauber, RE Nitric oxide-dependent and -independent vascular hyporeactivity in mesenteric arteries of portal hypertensive rats.
Br J Pharmacol. 1997; 121(5):1031-1037 Doi: 10.1038/sj.bjp.0701220 [OPEN ACCESS]
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** Hinterleitner, TA; Petritsch, W; Aichbichler, B; Fickert, P; Ranner, G; Krejs, GJ Combination of cyclosporine, azathioprine and prednisolone for perianal fistulas in Crohn's disease.
Z Gastroenterol. 1997; 35(8):603-608
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Kurzbericht/Letter

** Stauber, RE; Jauk, B; Fickert, P; Hausler, M Effect of pregnancy on carbohydrate-deficient transferrin: Absolute or relative values? Reply
ALCOHOL ALCOHOLISM. 1997; 32(4): 537-538. Doi: 10.1093/oxfordjournals.alcalc.a008290 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Eferl, R; Kenner, L; Fickert, P; Stauber, R; Denk, H; Zatloukal, K Validation of quantitative reverse transcription polymerase chain reaction for analysis of gene expression in liver biopsies.
HEPATOLOGY 1997 26: 1496-1496.
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** Fickert, P; Hinterleitner, TA; Aichbichler, B; Wenzl, HH; Petritsch, W Mycophenolate mofetil in patients with Crohn's disease
GASTROENTEROLOGY 1997 112: A972-A972.
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** Hinterleitner, TA; Fickert, P; Pamperl, I; Lindschinger, M; Anderhuber, W; Stammberger, H; Petritsch, W Percutaneous endoscopic gastrostomy prevents aspiration but has no effect on quality of life and physical activity in patients with radiation therapy for neck cancer
GASTROENTEROLOGY 1997 112: A879-A879.
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** Kessler, HH; Pierer, K; Fickert, P; Stauber, RE Virological and biochemical response to combined interferon-alpha plus ribavirin therapy in patients with chronic hepatitis C.
GASTROENTEROLOGY 1997 112: A1300-A1300.
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1996

Originalarbeit (Zeitschrift)

** Fickert, P; Ramschak, H; Kenner, L; Hoefler, G; Hinterleitner, TA; Petritsch, W; Klimpfinger, M; Krejs, GJ; Stauber, RE Acute Budd-Chiari syndrome with fulminant hepatic failure in a pregnant woman with factor V Leiden mutation.
Gastroenterology. 1996; 111(6):1670-1673 Doi: 10.1016/S0016-5085(96)70031-8 (- Case Report)
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** Schnedl, WJ; Reisinger, EC; Lipp, RW; Uggowitzer, M; Mischinger, HJ; Fickert, P; Krejs, GJ Biliary obstruction due to duodenojejunal intussusception in Peutz-Jeghers syndrome.
J Clin Gastroenterol. 1996; 23(3):220-223 Doi: 10.1097/00004836-199610000-00014 (- Case Report)
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** Stauber, RE; Jauk, B; Fickert, P; Häusler, M Increased carbohydrate-deficient transferrin during pregnancy: relation to sex hormones.
Alcohol Alcohol. 1996; 31(4):389-392 Doi: 10.1093/oxfordjournals.alcalc.a008167 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Fickert, P; Ramschak, H; Kenner, L; Hoefler, G; Hinterleitner, TA; Petritsch, W; Klimpfinger, M; Krejs, GJ; Stauber, RE Acute Budd Chiari syndrome with fulminant hepatic failure in a pregnant woman with factor V Leiden mutation.
HEPATOLOGY 1996 24: 1534-1534.
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** Heinemann, A; Fickert, P; Stauber, RE The effect of vasopressin analogues on the in vitro vascular reactivity in portal hypertension
HEPATOLOGY 1996 24: 1585-1585.
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1995

Abstract (Zeitschrift)

** HITNERLEITNER, TA; EHERER, AJ; FICKERT, P; PETRITSCH, W; BEUBLER, E; FRIEDLAND, T; KREJS, GJ SACCHAROMYCES-BOULARDII HAS NO EFFECT ON CHOLERA TOXIN-INDUCED WATER AND ELECTROLYTE SECRETION IN THE HUMAN JEJUNUM
GASTROENTEROLOGY 1995 108: A290-A290.
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** STAUBER, RE; JAUK, B; FICKERT, P; HÄUSLER, MCH CARBOHYDRATE-DEFICIENT TRANSFERRIN (CDT) IS ELEVATED IN PREMENOPAUSAL AND IN PREGNANT-WOMEN
HEPATOLOGY 1995 22: 1550-1550.
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