** = Publikationen gelistet in SCI/SSCI/Pubmed
** Liu, L; Zhou, S; Zaufel, A; Xie, Z; Racedo, S; Wagner, M; Zollner, G; Fickert, P; Zhang, Q
Bile acids regulate SF-1 to alter cholesterol balance in adrenocortical cells via S1PR2.
Biochem Biophys Res Commun. 2024; 692:149342
Doi: 10.1016/j.bbrc.2023.149342
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** Douschan, P; Kovacs, G; Sassmann, T; Stadlbauer, V; Avian, A; Foris, V; Tatscher, E; Durchschein, F; Rainer, F; Spindelboeck, W; Wagner, M; Kniepeiss, D; Zollner, G; Bachmaier, G; Fickert, P; Olschewski, H; Stauber, RE
Pulmonary vascular disease and exercise hemodynamics in chronic liver disease.
Respir Med. 2022; 202:106987
Doi: 10.1016/j.rmed.2022.106987
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** Panzitt, K; Zollner, G; Marschall, HU; Wagner, M
Recent advances on FXR-targeting therapeutics
MOL CELL ENDOCRINOL. 2022; 552: 111678
Doi: 10.1016/j.mce.2022.111678
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** Theiler-Schwetz, V; Schlager, H; Obermayer-Pietsch, B; Stojakovic, T; Fauler, G; Fickert, P; Zollner, G
Hypercortisolism in patients with cholestasis is associated with disease severity.
BMC Gastroenterol. 2021; 21(1):460
Doi: 10.1186/s12876-021-02045-4
[OPEN ACCESS]
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** Fabian, E; Wenisch, C; Eisner, F; Muhr, T; Bauer, PK; Prein, K; Maierhofer, U; Lax, SF; Krause, R; Zollner, G; Weihs, W; Krejs, GJ
Clinical-Pathological Conference Series from the Medical University of Graz : Case No 164: A 46-year-old man with abdominal pain, dyspnea and rapidly progressing multiorgan failure.
Wien Klin Wochenschr. 2021; 133(13-14):731-740
Doi: 10.1007/s00508-021-01841-y
(- Case Report)
[OPEN ACCESS]
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** Horvath, A; Durdevic, M; Leber, B; di Vora, K; Rainer, F; Krones, E; Douschan, P; Spindelboeck, W; Durchschein, F; Zollner, G; Stauber, RE; Fickert, P; Stiegler, P; Stadlbauer, V
Changes in the Intestinal Microbiome during a Multispecies Probiotic Intervention in Compensated Cirrhosis.
Nutrients. 2020; 12(6):
Doi: 10.3390/nu12061874
[OPEN ACCESS]
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** Jagersberger, L; Zollner, G; Binder, L
Complications following System of percutaneous endoscopic Gastrostomy (PEG).
WIEN KLIN WOCHENSCHR. Abstracts 51.Jahrestagung der Österreichischen Gesellschaft für Innere Medizin. 2020; 132(SUPPL 2):77-77.-51.Jahrestagung der Österreichischen Gesellschaft für Innere Medizin; SEP 24-26, 2020; Salzburg, AUSTRIA.
[Oral Communication]
Web of Science
** Liu, L; Panzitt, K; Racedo, S; Wagner, M; Platzer, W; Zaufel, A; Theiler-Schwetz, V; Obermayer-Pietsch, B; Müller, H; Höfler, G; Heinemann, A; Zollner, G; Fickert, P
Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1PR2, ERK and SF-1.
Liver Int. 2019; 39(11):2112-2123
Doi: 10.1111/liv.14052
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** Theiler-Schwetz, V; Zaufel, A; Schlager, H; Obermayer-Pietsch, B; Fickert, P; Zollner, G
Bile acids and glucocorticoid metabolism in health and disease.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(1):243-251
Doi: 10.1016/j.bbadis.2018.08.001
[OPEN ACCESS]
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** Horvath, A; Durdevic, M; Leber, B; di Vora, K; Rainer, F; Douschan, P; Krones, E; Spindelboeck, W; Durchschein, F; Zollner, G; Stauber, R; Fickert, P; Stiegler, P; Stadlbauer, V
Changes in the intestinal microbiome during probiotic intervention in cirrhosis
J HEPATOL. 2019; 70: E648-E648.-International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 10-14, 2019; Vienna, AUSTRIA.
Doi: 10.1016/S0618-8278(19)31290-3
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** Schwetz, V; Schlager, H; Obermayer-Pietsch, B; Stojakovic, T; Fauler, G; Fickert, P; Zollner, G
Alteration of glucocorticoid metabolism in patients with cholestasis
J HEPATOL. 2019; 70: E417-E418.-International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 10-14, 2019; Vienna, AUSTRIA.
Doi: 10.1016/S0618-8278(19)30822-9
[Poster]
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** Durchschein, F; Krones, E; Pollheimer, MJ; Zollner, G; Wagner, M; Raufman, JP; Fickert, P
Genetic loss of the muscarinic M3 receptor markedly alters bile formation and cholestatic liver injury in mice.
Hepatol Res. 2018; 48(3):E68-E77
Doi: 10.1111/hepr.12928
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** Pollheimer, MJ; Racedo, S; Mikels-Vigdal, A; Marshall, D; Bowlus, C; Lackner, C; Madl, T; Karlsen, TH; Hov, JR; Lyman, SK; Adamkewicz, J; Smith, V; Moreau, E; Zollner, G; Eide, TJ; Stojakovic, T; Scharnagl, H; Gruber, HJ; Stauber, RE; Trauner, M; Fickert, P
Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis.
J Hepatol. 2018; 69(2):368-377
Doi: 10.1016/j.jhep.2018.04.009
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** Haberl, J; Zollner, G; Fickert, P; Stadlbauer, V
To salt or not to salt?-That is the question in cirrhosis.
Liver Int. 2018; 38(7):1148-1159
Doi: 10.1111/liv.13750
[OPEN ACCESS]
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** Komarova, I; Horvath, A; Krones, E; Leber, B; Schmerboeck, B;
Durchschein, F; Zollner, G; Stauber,RE; Spindelböck, W;
Douschan, P; Stiegler, P; Kniepeiss, D; Stojakovic, T; Fauler, G;
Stadlbauer, V
Changes of bile acids profile in different etiologies of liver cirrhosis and its association with neutrophil response
JOURNAL OF HEPATOLOGY. 2018; 68(SUPP.1):S473-S473.-The International Liver Congress; APR 11–15, 2018; Paris, FRANCE.
Doi: 10.1016/S0168-8278(18)31193-0
[Poster]
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** Sassmann, T; Kovacs, G; Stauber, R; Foris, V; Pfeiffer, S; Gruber, F; Revelant, F; Stadlbauer, V; Kniepeiss, D; Zollner, G; Fickert, P; Avian, A; Olschewski, A; Olschewski, H; Douschan, P
Diastolic dysfunction and cardiopulmonary exercise capacity in patients with advanced liver disease-results from a prospective cross-sectional cohort
WIEN KLIN WOCHENSCHR. 2018; 130(19-20):627-627.-ÖGP Jahrestagung; OKT 18-20, 2018; Linz, Austria.
[Poster]
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** Sassmann, T; Kovacs, G; Stauber, RE; Revelant, F; Foris, V; Pfeiffer, S; Gruber, F; Stadlbauer, V; Kniepeiss, D; Zollner, G; Fickert, P; Avian, A; Olschewski, A; Olschewski, H; Douschan, P;
Impact of diastolic dysfunction on exercise capacity in patients with liver cirrhosis
European Respiratory Journal. 2018; 52(sup 62):-ERS International Congress; SEP 15 - 19, 2018; Paris, France.
Doi: 10.1183/13993003.congress-2018.PA2486
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** Dejaco, C; Stadlmayr, A; Duftner, C; Trimmel, V; Husic, R; Krones, E; Zandieh, S; Husar-Memmer, E; Zollner, G; Hermann, J; Gretler, J; Lackner, A; Ficjan, A; Datz, C; Axman, R; Zwerina, J
Ultrasound verified inflammation and structural damage in patients with hereditary haemochromatosis-related arthropathy.
Arthritis Res Ther. 2017; 19(1):243
Doi: 10.1186/s13075-017-1448-0
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** Douschan, P; Kovacs, G; Stadlbauer, V; Kniepeiss, D; Krones, E; Durchschein, F; Rainer, F; Spindelboeck, W; Wagner, M; Zollner, G; Avian, A; Fickert, P; Olschewski, A; Olschewski, H; Stauber, RE
Exercise capacity and exercise hemodynamics in the screening for pulmonary vascular disease (PVD) in patients with portal hypertension - results from a prospective cross-sectional study
J HEPATOL. 2017; 66(1):S568-S569.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS.
Doi: 10.1016/S0168-8278(17)31556-8
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** Douschan, P; Kovacs, G; Stauber, R; Foris, V; Pfeiffer, S; Gruber, F; Stadlbauer-Kollner, V; Kniepeiss, D; Zollner, G; Fickert, P; Avian, A; Olschewski, A; Olschewski, H
Exercise Hemodynamics In The Screening For Pulmonary Vascular Disease In Patients With Portal Hypertension - Results From A Prospective Cross-Sectional Study
AM J RESP CRIT CARE. 2017; 195: -International Conference of the American-Thoracic-Society (ATS); MAY 19-24, 2017; Washington, USA.
[Oral Communication]
Web of Science
** Horvath, A; Bashir, M; Schmerboeck, B; Rainer, F; Krones, E; Baumann-Durchschein, F; Douschan, P; Spindelboeck, W; Zollner, G; Stauber, RE; Fickert, P; Stiegler, P; Leber, B; Stadlbauer, V
Intestinal colonisation by Veillonella spp. is predictive for mortality in stable cirrhosis and could be partially reduced by a multispecies probiotic in a randomized placebo controlled trial
J HEPATOL. 2017; 66(1):S128-S128.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS.
Doi: 10.1016/S0168-8278(17)30524-X
[Poster]
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** Rainer, F; Horvath, A; Sandahl, TD; Leber, B; Schmerboeck, B; Blesl, A; Krones, E; Baumann-Durchschein, F; Douschan, P; Spindelboeck, W; Zollner, G; Stauber, RE; Fickert, P; Stiegler, P; Moller, HJ; Gronbaek, H; Stadlbauer, V
Macrophage activation markers sCD163 and mannose receptor predict survival and correlate with markers of gut permeability in patients with liver cirrhosis
J HEPATOL. 2017; 66(1):S368-S369.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS.
Doi: 10.1016/S0168-8278(17)31080-2
[Poster]
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** Horvath, A; Leber, B; Schmerboeck, B; Tawdrous, M; Zettel, G; Hartl, A; Madl, T; Stryeck, S; Fuchs, D; Lemesch, S; Douschan, P; Krones, E; Spindelboeck, W; Durchschein, F; Rainer, F; Zollner, G; Stauber, RE; Fickert, P; Stiegler, P; Stadlbauer, V
Randomised clinical trial: the effects of a multispecies probiotic vs. placebo on innate immune function, bacterial translocation and gut permeability in patients with cirrhosis.
Aliment Pharmacol Ther. 2016; 44(9):926-935
Doi: 10.1111/apt.13788
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** Wagner, M; Fickert, P; Zollner, G
Secretin and cholestasis, two sides of a coin.
Hepatology. 2016; 64(3):714-716
Doi: 10.1002/hep.28687
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** Fabian, E; Haas, B; Kump, P; Lipp, R; Kornprat, P; Lutfi, A; Talakic, E; Fuchsjäger, M; Spindelboeck, W; Lackner, C; Zollner, G; Krejs, GJ
Clinical-Pathological Conference Series from the Medical University of Graz : Case No 154: 32-year-old computer software engineer with nodular mass in the liver.
Wien Klin Wochenschr. 2016; 128(7-8):277-86
Doi: 10.1007/s00508-016-0965-1
(- Case Report)
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** Horvath, A; Leber, B; Fuchs, D; Schmerboeck, B; Tawdrous, M; Yueksel, O; Sherzay, K; Hartl, A; Lemesch, S; Spindelboeck, W; Fickert, P; Stauber, RE; Stiegler, P; Durchschein, F; Krones, E; Douschan, P; Zollner, G; Stadlbauer, V;
MULTISPECIES PROBIOTIC MAINTAINS HEALTH RELATED QUALITY OF LIFE IN CIRRHOSIS BETTER THAN PLACEBO.
J HEPATOL. 2016; 64: S249-S249.-EASL International Liver Congress; APR 13-17, 2016; Barcelona, SPAIN.
Doi: 10.1016/S0168-8278(16)00262-2
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** Krones, E; Fickert, P; Zitta, S; Neunherz, S; Artinger, K; Reibnegger, G; Durchschein, F; Wagner, D; Stojakovic, T; Stadlbauer, V; Fauler, G; Stauber, R; Zollner, G; Kniepeiss, D; Rosenkranz, AR
The chronic kidney disease epidemiology collaboration equation combining creatinine and cystatin C accurately assesses renal function in patients with cirrhosis.
BMC Nephrol. 2015; 16(4):196-196
Doi: 10.1186/s12882-015-0188-0
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** Stiedl, P; McMahon, R; Blaas, L; Stanek, V; Svinka, J; Grabner, B; Zollner, G; Kessler, SM; Claudel, T; Müller, M; Mikulits, W; Bilban, M; Esterbauer, H; Eferl, R; Haybaeck, J; Trauner, M; Casanova, E
Growth hormone resistance exacerbates cholestasis-induced murine liver fibrosis.
Hepatology. 2015; 61(2):613-626
Doi: 10.1002/hep.27408
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** Horvath, A; Leber, B; Krones, E; Zollner, G; Durchschein, F; Spindelboeck, W; Lemesch, S; Douschan, P; Fauler, G; Stojakovic, T; Fickert, P; Stauber, R; Stiegler, P; Stadlbauer, V
SERUM BILE ACIDS IN CIRRHOSIS DEPEND ON AETIOLOGY.
J HEPATOL. 2015; 62(S2):S344-S344.-50th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 22-26, 2015; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(15)30336-6
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** Horvath, A; Leber, B; Schmerboeck, B; Tawdrous, M; Hartl, A; Lemesch, S; Fickert, P; Stauber, RE; Stiegler, P; Durchschein, F; Krones, E; Douschan, P; Zollner, G; Spindelboeck, W; Oettl, K; Payerl, D; Stadlbauer, V
Probiotic supplementation improves liver function but fails to restore neutrophil phagocytosis in stable cirrhosis. A randomized, double-blind, placebo-controlled study
HEPATOLOGY. . 2015; 62: 1216A-1216A.-66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 13-17, 2015; San Francisco, CA.
[Oral Communication]
Web of Science
** Stiedl, P; McMahon, R; Blaas, L; Stanek, V; Svinka, J; Grabner, B; Zollner, G; Kressler, S; Claudel, T; Muller, M; Mikulits, W; Esterbauer, H; Eferl, R; Haybaeck, J; Trauner, M; Casanova, E
THE ROLE OF GROWTH HORMONE RECEPTOR IN LIVER FIBROSIS AND CANCER
J HEPATOL. 2015; 62: S792-S792.-50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver; APR 22-26, 2015; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(15)31366-0
[Poster]
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** Zollner, G; Thueringer, A; Lackner, C; Fickert, P; Trauner, M
Alterations of canalicular ATP-binding cassette transporter expression in drug-induced liver injury.
Digestion. 2014; 90(2):81-88
Doi: 10.1159/000365003
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** Hofer, H; Zollner, G; Fickert, P; Graziadei, I; Trauner, M
Clinical Course And Outcome Of Patients With Sclerosing Cholangitis In Critically Ill Patients (Sc-Cip): High Mortality Without Liver Transplantation
HEPATOLOGY. 2014; 60: 354A-354A.-65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 07-11, 2014; Boston, MA.
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** Horvath, A; Leber, B; Lemesch, S; Suppan, O; Yuksel, O; Sherzay, K; Zettel, G; Tawdrous, M; Spindelboeck, W; Durchschein, F; Krones, E; Douschan, P; Zollner, G; Fickert, P; Stauber, R; Stiegler, P; Stadlbauer, V
LISTING FOR LIVER TRANSPLANT: NO IMPACT ON THE QUALITY OF LIFE
TRANSPL INT. 2014; 27: 20-21.
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** Krones, E; Fritz, J; Schwarz, C; Durchschein, F; Eller, K; Zollner, G; Ribitsch, W; Stojakovic, T; Zitta, S; Buchgraber, J; Eppich, S; Rosenkranz, A; Fickert, P
Pathologische Harnzytologie als Hinweis für strukturelle Nierenschäden bei PatientInnen mit Zirrhose und Cholestase mit normaler Nierenfunktion.
WIEN KLIN WOCHENSCHR. 2014; 126(17-18):566-566.-45. Jahrestagung der Österreichischen Gesellschaft für Innere Medizin (ÖGIM); SEP 25-27, 2014; Salzburg, AUSTRIA.
[Poster]
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** Krones, E; Fritz, J; Schwarz, C; Durchschein, F; Eller, K; Zollner, G; Ribitsch, W; Stojakovic, T; Zitta, S; Buchgrabner, J; Rosenkranz, AR; Fickert, P
Microscopic Urinanalysis May Represent a Sensitive Test for Kidney Injury in Cirrhotic and Cholestatic Patients with Preserved Kidney Function.
HEPATOLOGY. 2014; 60: 328A-328A.-65th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 07-11, 2014; Boston, USA.
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** Stiedl, P; Blaas, L; Stanek, V; Svinka, J; Mahon, RM; Zollner, G; Claudel, T; Mueller, M; Mikulits, W; Esterbauer, H; Eferl, R; Haybaeck, J; Trauner, M; Casanova, E
The role of growth hormone receptor in liver fibrosis and cancer
CANCER RES. 2014; 74(19):
Doi: 10.1158/1538-7445.AM2014-5349
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** Zaufel, A; Wagner, M; Krones, E; Fickert, P; Zollner, G
Cholestasis and Bile Acids start the Adrenocortical Function, Salzburg, 25th-27th September, 2014
WIEN KLIN WOCHENSCHR. 2014; 126(17-18):570-571.
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** Fickert, P; Pollheimer, MJ; Silbert, D; Moustafa, T; Halilbasic, E; Krones, E; Durchschein, F; Thüringer, A; Zollner, G; Denk, H; Trauner, M
Differential effects of norUDCA and UDCA in obstructive cholestasis in mice.
J Hepatol. 2013; 58(6):1201-1208
Doi: 10.1016/j.jhep.2013.01.026
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** Jahn, S; Zollner, G; Lackner, C; Stauber, RE
Severe toxic hepatitis associated with dronedarone.
Curr Drug Saf. 2013; 8(3):201-202
Doi: 10.2174/15748863113089990031
(- Case Report)
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** A, Horvath; B, Leber; S, Lemesch; P, Stiegler; R, Stauber;
P, Fickert; G, Zollner; W, Spindelboeck; E, Krones;
F, Durchschein; P, Douschan; V, Stadlbauer
INCREASED GUT PERMEABILITY, ELEVATED ENDOTOXIN RELATED PROTEINS AND NEUTROPHIL DYSFUNCTION IN LIVER CIRRHOSIS.
Journal of Hepatology. 2013; 58(S1):S104--48th Annual meeting of the European Association for the Study of the Liver
; 24 April 2013 - 28 April 2013; Amsterdam.
Doi: 10.1016/S0168-8278(13)60246-9
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** Bernhardt, GA; Zollner, G; Cerwenka, H; Kornprat, P; Fickert, P; Bacher, H; Werkgartner, G; Müller, G; Zatloukal, K; Mischinger, HJ; Trauner, M
Hepatobiliary transporter expression and post-operative jaundice in patients undergoing partial hepatectomy.
Liver Int. 2012; 32(1):119-127
Doi: 10.1111/j.1478-3231.2011.02625.x
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** Krones, E; Zollner, G; Petritsch, W
Knotting of percutaneous endoscopic jejunostomy feeding tubes in two patients with Parkinson's disease and continuous Duodopa® treatment.
Z Gastroenterol. 2012; 50(2):213-216
Doi: 10.1055/s-0031-1281998
(- Case Report)
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Silbert, D; Gustafsson, U; Sahlin, S; Trauner, M
Combined rifampicin and ursodeoxycholic acid treatment does not amplify rifampicin effects on hepatic detoxification and transport systems in humans.
Digestion. 2012; 86(3):244-249
Doi: 10.1159/000341420
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** Durchschein, F; Pollheimer, MJ; Krones, E; Zollner, G; Trauner, M; Fickert, P
Genetic Loss of Muscarine-3 Receptor Decreases Biliary Bicarbonate Secretion and Aggravates Cholestatic Liver Injury in Mice
HEPATOLOGY. 2012; 56: 334A-334A.-63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 09-13, 2012; Boston, MA.
Web of Science
** Marschall, HU; Mueller, M; Wagner, M; Fickert, P; Zollner, G; Silbert, D; Lackner, C; Thorell, A; Trauner, M
HIGH LEVELS OF URSODEOXYCHOLIC ACID ACT AS FXR ANTAGONIST AND DEPLETE LIVER CHOLESTEROL DUE TO INCREASED BILE ACID SYNTHESIS IN MORBIDLY OBESE PATIENTS
J HEPATOL. . 2012; 56: S515-S515.-47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN.
Doi: 10.1016/S0168-8278(12)61319-1
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** Stiedl, P; Blaas, L; Stanek, V; Musteanu, M; Zollner, G; Esterbauer, H; Eferl, R; Trauner, M; Casanova, E
ROLE OF GROWTH HORMONE RECEPTOR IN LIVER FIBROSIS
J HEPATOL. 2012; 56: S147-S147.-47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN.
Doi: 10.1016/S0168-8278(12)60376-6
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Lackner, C; Thorell, A; Trauner, M
Ursodeoxycholic acid for treatment of fatty liver disease and dyslipidemia in morbidly obese patients.
Dig Dis. 2011; 29(1):117-118
Doi: 10.1159/000324146
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** Claudel, T; Zollner, G; Wagner, M; Trauner, M
Role of nuclear receptors for bile acid metabolism, bile secretion, cholestasis, and gallstone disease.
Biochim Biophys Acta. 2011; 1812(8):867-878
Doi: 10.1016/j.bbadis.2010.12.021
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** Trauner, M; Baghdasaryan, A; Claudel, T; Fickert, P; Halilbasic, E; Moustafa, T; Zollner, G
Targeting nuclear bile acid receptors for liver disease.
Dig Dis. 2011; 29(1):98-102
Doi: 10.1159/000324141
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** Wagner, M; Zollner, G; Trauner, M
Nuclear receptors in liver disease.
HEPATOLOGY. 2011; 53(3): 1023-1034.
Doi: 10.1002/hep.24148
[OPEN ACCESS]
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** Fickert, P; Silbert, D; Moustafa, T; Halilbasic, E; Krones, E; Durchschein, F; Thueringer, A; Pollheimer, MJ; Zollner, G; Denk, H; Trauner, M
DIFFERENTIAL EFFECTS OF NORUDCA AND UDCA IN OBSTRUCTIVE CHOLESTASIS IN MICE
HEPATOLOGY. 2011; 54: 775A-775A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA.
[Poster]
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** Blaas, L; Kornfeld, JW; Schramek, D; Musteanu, M; Zollner, G; Gumhold, J; van Zijl, F; Schneller, D; Esterbauer, H; Egger, G; Mair, M; Kenner, L; Mikulits, W; Eferl, R; Moriggl, R; Penninger, J; Trauner, M; Casanova, E
Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.
Hepatology. 2010; 51(4):1319-1326
Doi: 10.1002/hep.23469
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** Mair, M; Zollner, G; Schneller, D; Musteanu, M; Fickert, P; Gumhold, J; Schuster, C; Fuchsbichler, A; Bilban, M; Tauber, S; Esterbauer, H; Kenner, L; Poli, V; Blaas, L; Kornfeld, JW; Casanova, E; Mikulits, W; Trauner, M; Eferl, R
Signal transducer and activator of transcription 3 protects from liver injury and fibrosis in a mouse model of sclerosing cholangitis.
Gastroenterology. 2010; 138(7):2499-2508
Doi: 10.1053/j.gastro.2010.02.049
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** Trauner, M; Fickert, P; Baghdasaryan, A; Claudel, T; Halilbasic, E; Moustafa, T; Wagner, M; Zollner, G
New insights into autoimmune cholangitis through animal models.
Dig Dis. 2010; 28(1):99-104
Doi: 10.1159/000282072
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** Wagner, M; Zollner, G; Trauner, M
Nuclear receptor regulation of the adaptive response of bile acid transporters in cholestasis.
SEMIN LIVER DIS. 2010; 30(2): 160-177.
Doi: 10.1055/s-0030-1253225
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** Zollner, G; Wagner, M; Trauner, M
Nuclear receptors as drug targets in cholestasis and drug-induced hepatotoxicity.
Pharmacol Ther. 2010; 126(3):228-243
Doi: 10.1016/j.pharmthera.2010.03.005
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** Krones, E; Halilbasic, E; Grisold, A; Krause, R; Trauner, M; Fickert, P; Zollner, G
Acute hepatitis species as a result of contamination of a food supplement with Cytotoxin-producing Bacillus species.
WIEN KLIN WOCHENSCHR. 2010; 122(17-18):A10-A11.
[Poster]
Web of Science
** Zollner, G; Thueringer, A; Lackner, C; Fickert, P; Trauner, M
ALTERATIONS OF CANALICULAR ATP-BINDING CASSETTE TRANSPORTERS IN PATIENTS WITH DRUG-INDUCED LIVER INJURY
J HEPATOL. 2010; 52: S449-S449.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(10)61163-4
[Poster]
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** Fickert, P; Fuchsbichler, A; Moustafa, T; Wagner, M; Zollner, G; Halilbasic, E; Stöger, U; Arrese, M; Pizarro, M; Solís, N; Carrasco, G; Caligiuri, A; Sombetzki, M; Reisinger, E; Tsybrovskyy, O; Zatloukal, K; Denk, H; Jaeschke, H; Pinzani, M; Trauner, M
Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts.
Am J Pathol. 2009; 175(6):2392-2405
Doi: 10.2353/ajpath.2009.090114
[OPEN ACCESS]
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** Wagner, M; Zollner, G; Trauner, M
New molecular insights into the mechanisms of cholestasis.
J Hepatol. 2009; 51(3): 565-580.
Doi: 10.1016/j.jhep.2009.05.012
[OPEN ACCESS]
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** Zollner, G; Trauner, M
Nuclear receptors as therapeutic targets in cholestatic liver diseases.
Br J Pharmacol. 2009; 156(1):7-27
Doi: 10.1111/j.1476-5381.2008.00030.x
[OPEN ACCESS]
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** Blaas, L; Kornfield, JW; Zollner, G; Schramek, D; Esterbauer, H; Trauner, M; Casanova, E
ROLE OF STAT5 IN LIVER FIBROSIS
J HEPATOL. 2009; 50: 277-
Doi: 10.1016/S0168-8278(09)60279-8
[Poster]
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Lundasen, T; Gustafsson, U; Sahlin, S; Trauner, M
STIMULATION OF HEPATOBILIARY DETOXIFICATION AND TRANSPORT SYSTEMS IN HUMAN LIVER BY COMBINED TREATMENT WITH RIFAMPICIN AND URSODEOXYCHOLIC ACID
J HEPATOL. 2009; 50: 675-Vienna, Austria.
Doi: 10.1016/S0168-8278(09)60677-2
[Poster]
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** Zollner, G; Trauner, M
Mechanisms of cholestasis.
Clin Liver Dis. 2008; 12(1):1-26
Doi: 10.1016/j.cld.2007.11.010
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** Wagner, M; Zollner, G; Trauner, M
Ischemia and cholestasis: more than (just) the bile ducts!
Transplantation. 2008; 85(8):1083-1085
Doi: 10.1097/TP.0b013e31816b2393
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** Wagner, M; Zollner, G; Trauner, M
Nuclear bile acid receptor farnesoid X receptor meets nuclear factor-kappaB: new insights into hepatic inflammation.
Hepatology. 2008; 48(5):1383-1386
Doi: 10.1002/hep.22668
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** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, JS; Zatloukal, K; Denk, H; Jaeschke, H; Trauner, M
Hepatobiliary transporter expression in intercellular adhesion molecule 1 knockout and Fas receptor-deficient mice after common bile duct ligation is independent of the degree of inflammation and oxidative stress.
Drug Metab Dispos. 2007; 35(9):1694-1699
Doi: 10.1124/dmd.107.015610
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** Zollner, G; Fickert, P; Trauner, M
Cholestasis
WIEN KLIN WOCHENSCHR. 2007; 119: 125-140.
Doi: 10.1007/s11812-007-0029-6
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** Zollner, G; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M
Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis.
Liver Int. 2007; 27(7):920-929
Doi: 10.1111/j.1478-3231.2007.01506.x
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** Marschall, HU; Wagner, M; Zollner, G; Trauner, M
Clinical hepatotoxicity. Regulation and treatment with inducers of transport and cofactors.
MOL PHARM. 2007; 4(6): 895-910.
Doi: 10.1021/mp060133c
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** Wagner, M; Moustafa, T; Fickert, P; Zollner, G; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Absence of FXR protects mice from bile-infarcts in biliary obstruction by reduction of bile acid-independent bile flow: Implications for targeting FXR in treatment of cholestasis?
J HEPATOL. 2007; 46: S5-S5.-42th Annual Meeting, European Association for the Study of the Liver; April, 11-15, 2007; Barcelona, Spain.
Doi: 10.1016/S0168-8278(07)61603-1
[Oral Communication]
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** Zollner, G; Caligiuri, A; Fickert, P; Wagner, M; Silbert, D; Pinzani, M; Trauner, M
Expression of bile acid transport and detoxification systems and their regulatory nuclear receptors in human hepatic stellate cells
J HEPATOL. 2007; 46: S135-S135.-42th Annual Meeting, European Association for the Study of the Liver ; April 11-15, 2007; Barcelona, Spain.
Doi: 10.1016/S0168-8278(07)61944-8
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** Boyer, JL; Trauner, M; Mennone, A; Soroka, CJ; Cai, SY; Moustafa, T; Zollner, G; Lee, JY; Ballatori, N
Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents.
Am J Physiol Gastrointest Liver Physiol. 2006; 290(6):G1124-G1130
Doi: 10.1152/ajpgi.00539.2005
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** Fickert, P; Fuchsbichler, A; Marschall, HU; Wagner, M; Zollner, G; Krause, R; Zatloukal, K; Jaeschke, H; Denk, H; Trauner, M
Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.
Am J Pathol. 2006; 168(2):410-422
Doi: 10.2353/ajpath.2006.050404
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** Fickert, P; Wagner, M; Marschall, HU; Fuchsbichler, A; Zollner, G; Tsybrovskyy, O; Zatloukal, K; Liu, J; Waalkes, MP; Cover, C; Denk, H; Hofmann, AF; Jaeschke, H; Trauner, M
24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Gastroenterology. 2006; 130(2):465-481
Doi: 10.1053/j.gastro.2005.10.018
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** Marschall, HU; Wagner, M; Bodin, K; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Sjövall, J; Trauner, M
Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids.
J Lipid Res. 2006; 47(3):582-592
Doi: 10.1194/jlr.M500427-JLR200
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** Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Halilbasic, E; Denk, H; Marschall, HU; Trauner, M
Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Am J Physiol Gastrointest Liver Physiol. 2006; 290(5):G923-G932
Doi: 10.1152/ajpgi.00490.2005
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** Zollner, G; Marschall, HU; Wagner, M; Trauner, M
Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations.
Mol Pharm. 2006; 3(3): 231-251.
Doi: 10.1021/mp060010s
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** Zollner, G; Trauner, M
Molecular mechanisms of cholestasis.
Wien Med Wochenschr. 2006; 156(13-14):380-385
Doi: 10.1007/s10354-006-0312-7
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** Zollner, G; Fuchsbichler, A; Fickert, P; Denk, H; Trauner, M
Alterations of hepatic bilirubin and phospholipid export pumps MRP2 and MDR3 in patients with drug-induced liver injury
HEPATOLOGY. 44(4):381A-381A.
[Poster]
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** Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Helmut, D; Marschall, HU; Trauner, M
Role of nuclear bile acid receptor FXR in regulation of bile acid detoxification and organic solute transporter (OST-alpha/beta) expression in bile acid-fed mice
J HEPATOL. 44: S124-S124.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(06)80322-3
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Marschall, HU; Zatloukal, K; Denk, H
Oncosis represents the main type of cell death in mouse models of cholestasis.
J Hepatol. 2005; 42(3):378-385
Doi: 10.1016/j.jhep.2004.10.016
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** Geier, A; Zollner, G; Dietrich, CG; Wagner, M; Fickert, P; Denk, H; van Rooijen, N; Matern, S; Gartung, C; Trauner, M
Cytokine-independent repression of rodent Ntcp in obstructive cholestasis.
Hepatology. 2005; 41(3):470-477
Doi: 10.1002/hep.20594
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Diczfalusy, U; Gumhold, J; Silbert, D; Fuchsbichler, A; Benthin, L; Grundström, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M
Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans.
Gastroenterology. 2005; 129(2):476-485
Doi: 10.1016/j.gastro.2005.05.009
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** Wagner, M; Halilbasic, E; Marschall, HU; Zollner, G; Fickert, P; Langner, C; Zatloukal, K; Denk, H; Trauner, M
CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
Hepatology. 2005; 42(2):420-430
Doi: 10.1002/hep.20784
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** Zollner, G; Wagner, M; Fickert, P; Geier, A; Fuchsbichler, A; Silbert, D; Gumhold, J; Zatloukal, K; Kaser, A; Tilg, H; Denk, H; Trauner, M
Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver.
Am J Physiol Gastrointest Liver Physiol. 2005; 289(5):G798-G805
Doi: 10.1152/ajpgi.00319.2004
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** Zollner, G; Wagner, M; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Hepatobiliary transporter expression in human hepatocellular carcinoma.
Liver Int. 2005; 25(2):367-379
Doi: 10.1111/j.1478-3231.2005.01033.x
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** Trauner, M; Wagner, M; Fickert, P; Zollner, G
Molecular regulation of hepatobiliary transport systems: clinical implications for understanding and treating cholestasis.
J Clin Gastroenterol. 2005; 39(4 Suppl 2):S111-S124
Doi: 10.1097/01.mcg.0000155551.37266.26
[OPEN ACCESS]
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** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Krause, R; Zatloukal, K; Marschall, HU; Jaeschke, H; Denk, H; Trauner, M
Lithocholic acid feeding induces biliary obstruction and destructive cholangitis in mice
J HEPATOL. 2005; 42: 113-113.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science
** Fickert, P; Wagner, M; Marshall, HU; Fuchsbichler, A; Zollner, G; Zatloukal, K; Liu, J; Waalkes, MP; Cover, C; Denk, H; Hofmann, AF; Jaeschke, H; Trauner, M
24-norursodeoxycholic acid as novel therapeutic approach to sclerosing cholangitis in Mdr2 (ABCB4) knockout mice
HEPATOLOGY. 2005; 42: -56th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 11-15, 2005; San Francisco, CA.
Web of Science
** Geier, A; Zollner, G; Dietrich, CG; Wagner, M; Fickert, P; Denk, H; van Rooijen, N; Matern, S; Gartung, C; Trauner, M
Cytokine-independent repression of rodent Ntcp in obstructive cholestasis
J HEPATOL. 2005; 42: 114-114.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science
** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M
Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in human liver
GASTROENTEROLOGY. 2005; 128: A755-A755.
Web of Science
** Marschall, HU; Wagnr, M; Bodin, K; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Sjovall, J; Trauner, M
Fxr -/- mice adapt to obstructive cholestasis by enhanced phase I detoxification and renal elimination of bile acids
J HEPATOL. 2005; 42: 114-115.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science
** Soroka, C; Zollner, G; Mennone, A; Ballatori, N; Trauner, M; Boyer, JL
The heteromeric organic solute transporter, Ost alpha-Ost beta, is up-regulated in the liver of patients with primary biliary cirrhosis (PBC) and variably induced in rat and mouse cholangiocytes following bile duct ligation (BDL).
HEPATOLOGY. 2005; 42: -56th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 11-15, 2005; San Francisco, CA.
Web of Science
** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, J; Zatloukal, K; Jaeschke, H; Deck, H; Trauner, M
Role of inflammation for hepatobiliary transporter expression in ICAM-/- and lpr mice after common bile duct ligation
GASTROENTEROLOGY. 2005; 128: A89-A89.
Web of Science
** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, JS; Zatloukal, K; Denk, H; Jaeschke, H; Trauner, M
Alterations of hepatobiliary transporter expression in response to common bile duct ligation in mice are independent of ICAM-1 and FAS-receptor expression
J HEPATOL. 2005; 42: 115-115.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science
** Zollner, G; Wagner, M; Fickert, P; Gumhold, J; Silbert, D; Marschall, HU; Denk, H; Trauner, M
Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis
GASTROENTEROLOGY. 2005; 128: A691-A691.
Web of Science
** Zollner, G; Wagner, M; Fickert, P; Gumhold, J; Silbert, D; Marschall, HU; Denk, H; Trauner, M
Expression of key bile acid detoxification enzymes and the alternative bile acid export pump MRP4 in primary biliary cirrhosis
J HEPATOL. 2005; 42: 240-240.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science
** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Lammert, F; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Gastroenterology. 2004; 127(1):261-274
Doi: 10.1053/j.gastro.2004.04.009
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** Formann, E; Stauber, R; Denk, DM; Jessner, W; Zollner, G; Munda-Steindl, P; Gangl, A; Ferenci, P
Sudden hearing loss in patients with chronic hepatitis C treated with pegylated interferon/ribavirin.
AMER J GASTROENTEROL. 2004; 99(5): 873-877.
Doi: 10.1111/j.1572-0241.2004.30372.x
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** Stauber, RE; Krisper, P; Zollner, G; Iberer, F; Beuers, U; Trauner, M
Extracorporeal albumin dialysis in a patient with primary sclerosing cholangitis: effect on pruritus and bile acid profile.
Int J Artif Organs. 2004; 27(4):342-344
Doi: 10.1177/039139880402700411
(- Case Report)
Web of Science
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** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Biliary leakage of fluorescent bile acids in MDR2 knockout mice: Evidence for a critical role of bile duct leakage in the pathogenesis of sclerosing cholangitis
J HEPATOL. 2004; 40: 91-91.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90295-4
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** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Bile acids regurgitation from leaky bile ducts causes sclerosing cholangitis in Mdr2 knockout mice
GASTROENTEROLOGY. 2004; 126: A663-A663.
Web of Science
** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Marschall, HU; Zartloukal, K; Denk, H; Zsengeller, Z; Szabo, C
Oncosis represents the main type of cell death in mouse models of cholestasis: evidence for a critical role of poly(ADP-ribose) polymerase (PARP) activation in bile acid-induced hepatocytes death
FASEB J. 2004; 18: A558-A558.-Experimental Biology 2004 Meeting; APR 17-21, 2004; Washington, DC.
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Sahlin, S; Einarsson, C; Trauner, M
Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
GASTROENTEROLOGY. 2004; 126: A746-A746.
Web of Science
** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumholdt, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Sahlin, S; Einarsson, C; Trauner, M
Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
J HEPATOL. 2004; 40: 93-93.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90303-0
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** Wagner, M; Fickert, P; Marschall, HU; Zollner, G; Silbert, D; Fuchsbichler, A; Gumhold, J; Schuetz, JD; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M
Alternative exretory routes for accumulating bile acids via adaptive renal ABC transporter expression in common bile duct-ligated (CBDL) mice
GASTROENTEROLOGY. 2004; 126: A129-A130.
Web of Science
** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Gu, GL; Marschall, HU; Denk, H; Trauner, M
Role of adaptive hepatobiliary transporter expression and regulation of bile acid synthetic enzymes in MDR2-/- mice: A model for chronic cholestatic liver disease due to sclerosing cholangitis
J HEPATOL. 2004; 40: 163-163.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90557-0
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Fuchsbichler, A; Gumhold, J; Schuetz, JD; Gonzalez, FJ; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Adaptive renal ABC transporter expression in common bile duct-ligated mice
J HEPATOL. 2004; 40: 26-26.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90073-6
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Gender and pregnancy affect hepatic and renal ABC transporter expression in mice
J HEPATOL. 2004; 40: 94-94.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90307-8
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Hepatic and renal ABC transporter expression in mice depends on gender and changes in pregnancy
GASTROENTEROLOGY. 2004; 126: A130-A130.
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** Wagner, M; Halilbasic, E; Fickert, P; Zollner, G; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Denk, H; Trauner, M
Nuclear receptor (PXR, CAR) agonists induce adaptive hepatic transporter and enzyme expression in mouse liver
J HEPATOL. 2004; 40: 25-25.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90069-4
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** Wagner, M; Halilbasic, E; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Xenobiotic nuclear receptor (PXR, CAR) agonists coordinately stimulate a spectrum of detoxification enzymes and transport systems involved in the adaptive response to cholestasis in vivo.
HEPATOLOGY. 2004; 40: 489A-489A.-55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); OCT 29-NOV 02, 2004; Boston, MA.
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** Zollner, G; Halilbasic, E; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Cholic acid (CA) and ursodeoxycholic acid (UDCA) exert different effects on hepatic and renal expression of Mrp4 and Mrp6, two novel ABC transporters
GASTROENTEROLOGY. 2004; 126: A16-A16.
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** Zollner, G; Halilbasic, E; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Differential effects of ursodeoxycholic acid (UDCA) and cholic acid (CA) on hepatic and renal expression of MRP4 and MRP6, two novel abc transporters, in mice
J HEPATOL. 2004; 40: 25-25.
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** Zollner, G; Wagner, M; Fickert, P; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Guo, GL; Marschall, HU; Denk, H; Trauner, M
Mdr2(-/-) mice with sclerosing cholangitis: A model of chronic cholestasis to study the role of the adaptive response of hepatobiliary transport systems and bile acid synthetic enzymes
GASTROENTEROLOGY. 2004; 126: A751-A751.
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Tsybrovskyy, O; Zatloukal, K; Guo, GL; Schuetz, JD; Gonzalez, FJ; Marschall, HU; Denk, H; Trauner, M
Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice.
Gastroenterology. 2003; 125(3):825-838
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Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine.
J Hepatol. 2003; 39(4):480-488
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Marschall, HU; Zatloukal, K; Denk, H; Trauner, M
Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.
J Hepatol. 2003; 38(6):717-727
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** Wölfler, A; Bauer, F; Zollner, G; Weber, K; Sill, H; Linkesch, W
Fatal sepsis after thalidomide/dexamethasone treatment in two patients with multiple myeloma.
Haematologica. 2003; 88(4): ELT12-ELT12.
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Inhibition of poly(ADP-ribose) polymerase (PARP) protects mice from cholestatic liver injury.
HEPATOLOGY 2003 38: 576A-576A.
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** Wagner, M; Fickert, P; Fuchsbichler, A; Silbert, D; Gumhold, J; Zollner, G; Zatloukal, K; Marschall, HU; Schuetz, JD; Gonzalez, FJ; Denk, H; Trauner, M
Hepatic and renal ABC transporter expression as critical determinants of ursodeoxycholic acid-induced bile infarcts in bile duct-ligated mice.
HEPATOLOGY 2003 38: 688A-689A.
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Marschall, HU; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M
The role of the bile acid receptor FXR in determining ATP-binding cassette (ABC) transporter expression and liver injury in common bile duct ligated (CBDL) mice
J HEPATOL 2003 38: 190-190.
Doi: 10.1016/S0168-8278(03)80031-4
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Tsybrovskyy, O; Gonzalez, FJ; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Role of nuclear bile acid receptor, FXR, in determining ATP-binding cassette (ABC) transporter expression and cholestatic liver injury in common bile duct-ligated mice
GASTROENTEROLOGY 2003 124: A697-A698.
Doi: 10.1016/S0016-5085(03)83527-8
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Guo, G; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M
Role of nuclear bile salt receptors Fxr and Pxr in mediating adaptive hepatobiliary transporter response to cholic acid (CA) in mouse liver
GASTROENTEROLOGY 2003 124: A59-A59.
Doi: 10.1016/S0016-5085(03)80292-5
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Zatloukal, K; Denk, H; Trauner, M
Role of short heterodimer partner (SHP) -dependent and -independent pathways for regulation of Na+/taurocholate cotransporter (NTCP) expression in cholestatic mouse models.
J HEPATOL. 2003; 38(2):9-10.-38th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; MAR 29-APR 01, 2003; ISTANBUL, TURKEY.
Doi: 10.1016/S0168-8278(03)80442-7
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Zatloukal, K; Denk, H; Trauner, M
Regulation of the Na+/taurocholate cotransporter Ntcp via short heterodimer partner (SHP)-dependent or SHP-independent mechanims depends on the type of cholestatic injury
GASTROENTEROLOGY 2003 124: A730-A730.
Doi: 10.1016/S0016-5085(03)83688-0
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** Zollner, G; Fickert, P; Wagner, M; Fuchsbichler, A; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M
Induction of intestinal multidrug resistance-associated proteins 2 and 3 (Mrp2, Mrp3) by cholic acid (CA) and ursodeoxycholic acid (UDCA) in mice.
HEPATOLOGY 2003 38: 689A-689A.
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** Fickert, P; Zollner, G; Fuchsbichler, A; Stumptner, C; Weiglein, AH; Lammert, F; Marschall, HU; Tsybrovskyy, O; Zatloukal, K; Denk, H; Trauner, M
Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles.
Gastroenterology. 2002; 123(4):1238-1251
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Stumptner, C; Zatloukal, K; Denk, H; Trauner, M
Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice.
Am J Physiol Gastrointest Liver Physiol. 2002; 282(1):G184-G191
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J Gastroenterol Hepatol. 2002; 17 Suppl(6):S105-S112
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** Fickert, P; Zollner, G; Silbert, D; Fuchsbichler, A; Arbeiter, S; Gonzalez, F; Denk, H; Trauner, M
Adaptive hepatic and renal transporter regulation in cholic acid (CA)-fed mice: Role of nuclear bile acid receptor (FXR).
HEPATOLOGY 2002 36: 454A-454A.
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** Zollner, G; Fickert, P; Arbeiter, S; Silbert, D; Fuchsbichler, A; Gonzalez, F; Zatloukal, K; Denk, H; Trauner, M
Ursodeoxycholic acid (UDCA) feeding induces adaptive hepatic and renal ABC-transporter expression in mice.
HEPATOLOGY 2002 36: 454A-454A.
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Stumptner, C; Neuberger, J; Zatloukal, K; Denk, H; Trauner, M
Alterations of hepatobiliary transporter expression in primary biliary cirrhosis (PBC)
J HEPATOL 2002 36: 28-29.
Doi: 10.1016/S0168-8278(02)80086-1
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Messenger RNA expression of nuclear, orphan receptors and hepatocyte nuclear factor 1 alpha (HNF-1 alpha) in inflammation-associated cholestasis (IC) and primary biliary cirrhosis
HEPATOLOGY 2002 36: 454A-454A.
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** Fickert, P; Zollner, G; Fuchsbichler, A; Stumptner, C; Pojer, C; Zenz, R; Lammert, F; Stieger, B; Meier, PJ; Zatloukal, K; Denk, H; Trauner, M
Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver.
Gastroenterology. 2001; 121(1):170-183
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** Zollner, G; Fickert, P; Zenz, R; Fuchsbichler, A; Stumptner, C; Kenner, L; Ferenci, P; Stauber, RE; Krejs, GJ; Denk, H; Zatloukal, K; Trauner, M
Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases.
Hepatology. 2001; 33(3):633-646
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Genetic disorders and molecular mechanisms in cholestatic liver disease--a clinical approach.
Semin Gastrointest Dis. 2001; 12(2):66-88
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Mdr2-p-glycoprotein-deficient (Mdr2-/-) mouse - A new model for primary sclerosing cholangitis (PSC)?
HEPATOLOGY 2001 34: 509A-509A.
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** Fickert, P; Zollner, G; Fuchsbichler, A; Stumptner, C; Lammert, F; Zaltloukal, K; Denk, H; Trauner, M
Ursodeoxycholic acid (UDCA) feeding aggravates liver injury in bile duct-ligated and Mdr2 kockout mice
J HEPATOL 2001 34: 182-182.
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** Fickert, P; Zollner, G; Fuchsbichler, A; Stumptner, C; Lammert, F; Zatloukal, K; Denk, H; Trauner, M
Ursodeoxycholic acid feeding aggravates liver injury in bile duct-ligated mice
GASTROENTEROLOGY 2001 120: A1-A1.
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** Zollner, G; Fickert, P; Fuchsbichler, A; Stumptner, C; Denk, H; Zatloukal, K; Ferenci, P; Trauner, M
Expression of multidrug resistance P-glycoproteins (MDRs) and multidrug resistance-associated proteins (MRPs) in Wilson disease (WD)
J HEPATOL 2001 34: 188-188.
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** Zollner, G; Fickert, P; Fuchsbichler, A; Stumptner, C; Denk, H; Zatloukal, K; Trauner, M
Multidrug resistance P-glycoproteins (MDR) and multidrug resistance-associated proteins (MRP) are not overexpressed in human hepatocellular carcinomas (HCC).
J HEPATOL 2001 34: 189-189.
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Stumptner, C; Ott, P; Zatloukal, K; Denk, H; Trauner, M
Expression of multidrug resistance p-glycoproteins (MDR), multidrug resistance-associated proteins (MRP) and bile acid transporters in human hepatocellular carcinomas (HCC).
HEPATOLOGY 2001 34: 665A-665A.
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M; Franzens, K
Induction of the transcriptional repressor short heterodimer partner 1 precedes down-regulation of the Na+/taurocholate cotransporter in bile duct-ligated mice.
HEPATOLOGY 2001 34: 469A-469A.
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** Trauner, M; Fickert, P; Zollner, G
Abnormal hepatic sinusoidal bile acid transport: new insights into the pathogenesis of cholestasis?
Gastroenterology. 2001; 120(1):321-323
Doi: 10.1053/gast.2001.21380
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** Fickert, P; Zenz, R; Zollner, G; Pojer, C; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Regulation of hepatocellular transporter expression depends on bile acid hydrophobicity in mice.
GASTROENTEROLOGY 2000 118: 168-168.
Doi: 10.1016/S0016-5085(00)85876-X
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** Trauner, M; Fickert, F; Zenz, R; Pojer, C; Fuchsbichler, A; Zollner, G; Denk, H; Zatloukal, K
Role of Kupffer cells in regulation of multidrug resistance (mdr) P-glycoprotein expression in intrahepatic and obstructive cholestasis.
HEPATOLOGY 1999 30: 463A-463A.
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