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Olschewski Andrea |

** = Publications listed in SCI/SSCI/Pubmed

2025

Full paper/article (Journal)

** Birnhuber, A; Biasin, V; Jain, PP; Kwiatkowski, G; Boiarina, E; Wilhelm, J; Ahrens, K; Nagaraj, C; Olschewski, A; Witzenrath, M; Chlopicki, S; Marsh, LM; Tabeling, C; Kwapiszewska, G Pulmonary vascular remodeling in Fra-2 transgenic mice is driven by type 2 inflammation and accompanied by pulmonary vascular hyperresponsiveness.
Am J Physiol Lung Cell Mol Physiol. 2025; Doi: 10.1152/ajplung.00274.2024
Web of Science PubMed FullText FullText_MUG

 

** Bordag, N; Nagy, BM; Zügner, E; Ludwig, H; Foris, V; Nagaraj, C; Biasin, V; Kovacs, G; Kneidinger, N; Bodenhofer, U; Magnes, C; Maron, BA; Ulrich, S; Lange, TJ; Eichmann, TO; Hoetzenecker, K; Pieber, T; Olschewski, H; Olschewski, A Lipid Ratios for Diagnosis and Prognosis of Pulmonary Hypertension.
Am J Respir Crit Care Med. 2025;
PubMed

 

** Crnkovic, S; Thekkekara, Puthenparampil, H; Mulch, S; Biasin, V; Radic, N; Wilhelm, J; Bartkuhn, M; Bonyadi, Rad, E; Wawrzen, A; Matzer, I; Mitra, A; Leib, RD; Nagy, BM; Sahu-Osen, A; Valzano, F; Bordag, N; Evermann, M; Hoetzenecker, K; Olschewski, A; Ljubojevic-Holzer, S; Wygrecka, M; Stenmark, K; Marsh, LM; de, Jesus, Perez, V; Kwapiszewska, G Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease.
Elife. 2025; 13: Doi: 10.7554/eLife.98558 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

2024

Full paper/article (Journal)

** Bracic, M; Nagy, BM; Plohl, O; Lackner, F; Steindorfer, T; Fischer, RC; Heinze, T; Olschewski, A; Kleinschek, KS; Nagaraj, C; Mohan, T Antithrombogenic polysaccharide coatings to improve hemocompatibility, protein-repellence, and endothelial cell response
ISCIENCE. 2024; 27(9): 110692 Doi: 10.1016/j.isci.2024.110692 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

** Csáki, R; Nagaraj, C; Almássy, J; Khozeimeh, MA; Jeremic, D; Olschewski, H; Dobolyi, A; Hoetzenecker, K; Olschewski, A; Enyedi, P; Lengyel, M The TREK-1 potassium channel is a potential pharmacological target for vasorelaxation in pulmonary hypertension.
Br J Pharmacol. 2024; Doi: 10.1111/bph.16426
Web of Science PubMed FullText FullText_MUG

 

** Guignabert, C; Aman, J; Bonnet, S; Dorfmüller, P; Olschewski, AJ; Pullamsetti, S; Rabinovitch, M; Schermuly, RT; Humbert, M; Stenmark, KR Pathology and pathobiology of pulmonary hypertension: current insights and future directions.
Eur Respir J. 2024; Doi: 10.1183/13993003.01095-2024 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

** Zeder, K; Marsh, LM; Avian, A; Brcic, L; Birnhuber, A; Douschan, P; Foris, V; Sassmann, T; Hoetzenecker, K; Boehm, PM; Kwapiszewska, G; Olschewski, A; Olschewski, H; Kovacs, G Compartment-specific remodeling patterns in end-stage chronic obstructive pulmonary disease with and without severe pulmonary hypertension.
J Heart Lung Transplant. 2024; 43(7):1090-1101 Doi: 10.1016/j.healun.2024.02.1044
Web of Science PubMed FullText FullText_MUG

 

Review

** Madreiter-Sokolowski, CT; Hiden, U; Krstic, J; Panzitt, K; Wagner, M; Enzinger, C; Khalil, M; Abdellatif, M; Malle, E; Madl, T; Osto, E; Schosserer, M; Binder, CJ; Olschewski, A Targeting organ-specific mitochondrial dysfunction to improve biological aging.
Pharmacol Ther. 2024; 262:108710 Doi: 10.1016/j.pharmthera.2024.108710
Web of Science PubMed FullText FullText_MUG

 

Editorial

** Foris, V; Olschewski, A Editorial: Pulmonary hypertension: from bench to bedside.
Front Physiol. 2024; 15: 1421654 Doi: 10.3389/fphys.2024.1421654 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Abstract (Journal)

** Chandran, N; Sharma, N; Almassy, J; Enyedi, P; Olschewski, H; Olschewski, A Pan-PPAR agonists directly target BK channels for the acute relaxation of pulmonary arteries
EUR RESPIR J. 2024; 64: PA2643- Doi: 10.1183/13993003.congress-2024.PA2643 [Poster]
Web of Science FullText FullText_MUG

 

** Csáki, R; Foris, V; Eichstaedt, CA; Dobolyi, A; Grünig, E; Mészáros, F; Nagaraj, C; Almássy, J; Halank, M; Olschewski, A; Olschewski, H; Enyedi, P Functional Characterization of Novel K_V1.5 Variants in PAH
WIEN KLIN WOCHENSCHR. Abstracts. 2024; 136: S523-S523.-48. Jahrestagung der ÖGP - 8. Jahrestagung der OGTC; SEP 26-28, 2024; Vienna, AUSTRIA. [Oral Communication]
Web of Science

 

** Foris, V; Kim, K; Martini, L; Boueiz, A; Kovacs, G; Douschan, P; Kwapiszewska, G; Olschewski, A; Olschewski, H; Silverman, EK; Cho, M Missense variation in pulmonary hypertension associated with chronic obstructive pulmonary disease
WIEN KLIN WOCHENSCHR. 2024; 136: S550-S551.-Österreichische Gesellschaft für Pneumologie; SEP 26-28, 2024; Vienna, Austria. [Poster]
Web of Science

 

** Foris, V; Kim, K; Martini, L; El Boueiz, A; Kovacs, G; Douschan, P; Kwapiszewska, G; Olschewski, A; Olschewski, H; Silverman, EK; Cho, MH Nonsynonymous Genetic Variant Burden in Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease
AM J RESP CRIT CARE. 2024; 209: -American Thoracic Society; MAY 17-22, 2024; San Diego, USA. [Poster]
Web of Science

 

** Guntur, D; Jeremic, D; Foris, V; Olschewski, H; Olschewski, A; Nagaraj, C Relevance of BKCa Channels in Pulmonary Endothelial Dysfunction
AM J RESP CRIT CARE. Abstracts. 2024; 209: -ATS International Conference; MAY 17-22, 2024; San Diego, USA. [Poster]
Web of Science

 

** Guntur, D; Myronenko, O; Jeremic, D; Olschewski, H; Olschewski, A; Nagaraj, C Critical Role of BKCa Channels in the Pathophysiology of Acute Lung Injury
WIEN KLIN WOCHENSCHR. 2024; 136: S522-S522. [Oral Communication]
Web of Science

 

** Jeremic, D; Nagy, B; Eller, K; Hötzenecker, K; Olschewski, H; Olschewski, A; Nagaraj, C Impact of GLP1R and its agonists in pulmonary circulation
EUR RESPIR J. 2024; 64: PA2641- Doi: 10.1183/13993003.congress-2024.PA2641 [Poster]
Web of Science FullText FullText_MUG

 

** Myronenko, O; Foris, V; Olschewski, A; Olschewski, H Pre-capillary pulmonary hypertension in COPD: are there distinctive ironome-associated endotypes?
EUR RESPIR J. ERS Congress 2024 abstracts . 2024; 64: PA3428--ERS Congress 2024; SEP 7-11, 2024; Vienna, AUSTRIA. Doi: 10.1183/13993003.congress-2024.PA3428 [Poster]
Web of Science FullText FullText_MUG

 

** Myronenko, O; Foris, V; Olschewski, A; Olschewski, H Iron status and circulating iron-associated factors in COPD patients with and without severe pulmonary hypertension
WIEN KLIN WOCHENSCHR. Abstracts. 2024; 136: S527-S527.-48. Jahrestagung der ÖGP - 8. Jahrestagung der OGTC; SEP 26-28, 2024; Vienna, AUSTRIA. [Poster]
Web of Science

 

** Nagaraj, C; Douschan, P; Sassmann, T; Kneidinger, N; Olschewski, A; von Lewinski, D; Olschewski, H Pulmonary Vasodilation Induced by Red Wine: The Critical Role of Endothelial Nitric Oxide
WIEN KLIN WOCHENSCHR. 2024; 136: S526-S527. [Poster]
Web of Science

 

** Waked, P; Birnhuber, A; Kotzbeck, P; Foessl, I; Zabini, D; Marsh, LM; Crnkovic, S; Olschewski, A; Obermayer-Pietsch, B; Kwapiszewska, G; Biasin, V Towards precision medicine: Systemic Sclerosis research in light of sex- differences
EUR RESPIR J. 2024; 64: PA2639- Doi: 10.1183/13993003.congress-2024.PA2639 [Poster]
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** Waked, P; Birnhuber, A; Kotzbeck, P; Foessl, I; Zabini, D; Marsh, LM; Crnkovic, S; Olschewski, A; Obermayer-Pietsch, B; Kwapiszewska, G; Biasin, V The Role of Testosterone in Modulating Systemic Sclerosis Severity: A Preclinical Study
WIEN KLIN WOCHENSCHR. 2024; 136: S527-S528. [Poster]
Web of Science

 

2023

Full paper/article (Journal)

** Crnkovic, S; Rittchen, S; Jandl, K; Gindlhuber, J; Zabini, D; Mutgan, AC; Valzano, F; Boehm, PM; Hoetzenecker, K; Toller, W; Veith, C; Heinemann, A; Schermuly, RT; Olschewski, A; Marsh, LM; Kwapiszewska, G Divergent Roles of Ephrin-B2/EphB4 Guidance System in Pulmonary Hypertension.
Hypertension. 2023; 80(2):e17-e28 Doi: 10.1161/HYPERTENSIONAHA.122.19479
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** Eichstaedt, CA; Bikou, O; Sommer, N; Schermuly, RT; Pullamsetti, SS; Weissmann, N; Harbaum, L; Tabeling, C; Wißmüller, M; Foris, V; Kuebler, WM; Hinderhofer, K; Olschewski, A; Kwapiszewska, G [Genetic diagnostics and molecular approaches in pulmonary arterial hypertension].
Pneumologie. 2023; 77(11): 862-870. Doi: 10.1055/a-2145-4663
Web of Science PubMed FullText FullText_MUG

 

** Foris, V; Kovacs, G; Avian, A; Bálint, Z; Douschan, P; Ghanim, B; Klepetko, W; Olschewski, A; Olschewski, H Apelin-17 to diagnose idiopathic pulmonary arterial hypertension: A biomarker study.
Front Physiol. 2022; 13: 986295 Doi: 10.3389/fphys.2022.986295 [OPEN ACCESS]
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** Lackner, F; Knechtl, I; Novak, M; Nagaraj, C; Stiglic, AD; Kargl, R; Olschewski, A; Kleinschek, KS; Mohan, T 3D-Printed Anisotropic Nanofiber Composites with Gradual Mechanical Properties
ADV MATER TECHNOL-US. 2023; Doi: 10.1002/admt.202201708
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** Mutgan, AC; Jandl, K; Radic, N; Valzano, F; Kolb, D; Hoffmann, J; Foris, V; Wilhelm, J; Boehm, PM; Hoetzenecker, K; Olschewski, A; Olschewski, H; Heinemann, A; Wygrecka, M; Marsh, LM; Kwapiszewska, G Pentastatin, a matrikine of the collagen IVα5, is a novel endogenous mediator of pulmonary endothelial dysfunction.
Am J Physiol Cell Physiol. 2023; 325(5):C1294-C1312 Doi: 10.1152/ajpcell.00391.2023 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Short report/Letter

** Olschewski, H; Zeder, K; Douschan, P; Sassmann, T; Foris, V; Olschewski, A; Kovacs, G Let's Talk About Respiratory Swings!
Am J Respir Crit Care Med. 2023; 208(12):1338-1340 Doi: 10.1164/rccm.202309-1637LE [OPEN ACCESS]
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Review

** Myronenko, O; Foris, V; Crnkovic, S; Olschewski, A; Rocha, S; Nicolls, MR; Olschewski, H Endotyping COPD: hypoxia-inducible factor-2 as a molecular "switch" between the vascular and airway phenotypes?
Eur Respir Rev. 2023; 32(167): Doi: 10.1183/16000617.0173-2022 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Abstract (Journal)

** Bordag, N; Nagy, BM; Zügner, E; Ludwig, H; Foris, V; Nagaraj, C; Biasin, V; Bodenhofer, U; Magnes, C; Maron, BA; Ulrich, S; Lange, TJ; Hötzenecker, K; Pieber, T; Olschewski, H; Olschewski, A Late Breaking Abstract - Metabolic phenotype determines outcome of pulmonary arterial hypertension
EUR RESPIR J. 2023; 62: PA5192--ERS International Congress 2023 ; SEP 9-13, 2023; Milano, Italy. Doi: 10.1183/13993003.congress-2023.PA5192 [Poster]
Web of Science FullText FullText_MUG

 

** Foris, V; Brcic, L; Eichstaedt, CA; Kovacs, G; Douschan, P; Zeder, K; Sassmann, T; Hinderhofer, K; Grunig, E; Olschewski, A; Olschewski, H Pulmonary Vascular Remodeling May Precede Pulmonary Arterial Pressure Elevation in Pulmonary Veno-occlusive Disease- A Report of Three Cases
AM J RESP CRIT CARE. 2023; 207: -International Conference of the American-Thoracic-Society (ATS); MAY 19-24, 2023; Washington, DC. [Poster]
Web of Science

 

** Guntur, D; Sinha, M; Foris, V; Olschewski, H; Olschewski, A; Nagaraj, C Unveiling the role of BK_Ca channels in pulmonary health and hypertension
WIEN KLIN WOCHENSCHR. Abstracts. 2023; 135(19-20):561-561.-47. Jahrestagung der ÖGP - 7. Jahrestagung der ÖGTC; OCT 23-25, 2023; Graz, Austria. [Oral Communication]
Web of Science

 

** Jeremic, D; Nagy, B; Eller, K; Hötzenecker, K; Olschewski, H; Olschewski, A; Nagaraj, C Assessment of incretin receptor-GLP1R function in human lung vasculature
WIEN KLIN WOCHENSCHR. Abstracts. 2023; 135(19-20):568-568.-47. Jahrestagung der ÖGP - 7. Jahrestagung der ÖGTC; OCT 23-25, 2023; Graz, Austria. [Oral Communication]
Web of Science

 

** Jeremic, D; Nagy, B; Nagaraj, C; Hötzenecker, K; Olschewski, H; Olschewski, A Exploring the GLP-1-GLP-1R axis in pulmonary hypertension
J VASC RES. 2023; 60(SUPP1): 24-24. [Poster]
Web of Science

 

** Myronenko, O; John, N; Foris, V; Brcic, L; Wöhlkonig, C; Wurm, R; Olschewski, A; Olschewski, H Computational approach in phenotyping of monocyte/macrophage subsets in bronchoalveolar lavage fluid of COPD patients: prospective study
WIEN KLIN WOCHENSCHR. Abstracts. 2023; 135(19-20):565-566.-47. Jahrestagung der ÖGP - 7. Jahrestagung der ÖGTC; OCT 23-25, 2023; Graz, Austria. [Poster]
Web of Science

 

** Zeder, K; Marsh, LM; Avian, A; Brcic, L; Birnhuber, A; Douschan, P; Foris, V; Sassmann, T; Hoetzenecker, K; Boehm, P; Kwapiszewska, G; Olschewski, A; Olschewski, H; Kovacs, G Compartment-specific Remodeling of End-stage Chronic Obstructive Pulmonary Disease Patients With Severe Pulmonary Hypertension Based on Histological Lung Tissue Samples
AM J RESP CRIT CARE. 2023; 207: -International Conference of the American-Thoracic-Society (ATS); MAY 19-24, 2023; Washington, DC. [Oral Communication]
Web of Science

 

Pre-print

** Bordag, N; Nagy, BM; Zügner, E; Ludwig, H; Foris, V; Nagaraj, C; Biasin, V; Bodenhofer, U; Magnes, C; Maron, BA; Ulrich, S; Lange, TJ; Hötzenecker, K; Pieber, T; Olschewski, H; Olschewski, A Lipidomics for diagnosis and prognosis of pulmonary hypertension.
medRxiv. 2023; Doi: 10.1101/2023.05.17.23289772 [OPEN ACCESS]
PubMed FullText FullText_MUG

 

2022

Full paper/article (Journal)

** Birnhuber, A; Jandl, K; Biasin, V; Fließer, E; Valzano, F; Marsh, LM; Krolczik, C; Olschewski, A; Wilhelm, J; Toller, W; Heinemann, A; Olschewski, H; Wygrecka, M; Kwapiszewska, G Pirfenidone exacerbates Th2-driven vasculopathy in a mouse model of systemic sclerosis-associated interstitial lung disease.
Eur Respir J. 2022; 60(4): Doi: 10.1183/13993003.02347-2021 [OPEN ACCESS]
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** Dixon, PH; Levine, AP; Cebola, I; Chan, MMY; Amin, AS; Aich, A; Mozere, M; Maude, H; Mitchell, AL; Zhang, J; Chambers, J; Syngelaki, A; Donnelly, J; Cooley, S; Geary, M; Nicolaides, K; Thorsell, M; Hague, WM; Estiu, MC; Marschall, HU; Gale, DP; Williamson, C, , NIHR, BioResource;Genomics, England, Research, Consortium, Collaborators GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements.
Nat Commun. 2022; 13(1): 4840 Doi: 10.1038/s41467-022-29931-z [OPEN ACCESS]
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** Erfinanda, L; Zou, L; Gutbier, B; Kneller, L; Weidenfeld, S; Michalick, L; Lei, D; Reppe, K; Teixeira, Alves, LG; Schneider, B; Zhang, Q; Li, C; Fatykhova, D; Schneider, P; Liedtke, W; Sohara, E; Mitchell, TJ; Gruber, AD; Hocke, A; Hippenstiel, S; Suttorp, N; Olschewski, A; Mall, MA; Witzenrath, M; Kuebler, WM Loss of endothelial CFTR drives barrier failure and edema formation in lung infection and can be targeted by CFTR potentiation.
Sci Transl Med. 2022; 14(674): eabg8577 Doi: 10.1126/scitranslmed.abg8577
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** Harbaum, L; Rhodes, CJ; Wharton, J; Lawrie, A; Karnes, JH; Desai, AA; Nichols, WC; Humbert, M; Montani, D; Girerd, B; Sitbon, O; Boehm, M; Novoyatleva, T; Schermuly, RT; Ghofrani, HA; Toshner, M; Kiely, DG; Howard, LS; Swietlik, EM; Gräf, S; Pietzner, M; Morrell, NW; Wilkins, MR, , U.K., National, Institute, for, Health, Research, BioResource, Rare, Diseases, Consortium, U.K., Pulmonary, Arterial, Hypertension, Cohort, Study, Consortium, and, U.S., Pulmonary, Arterial, Hypertension, Biobank, Consortium Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension.
Am J Respir Crit Care Med. 2022; 205(12): 1449-1460. Doi: 10.1164/rccm.202109-2106OC [OPEN ACCESS]
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** Nagaraj, C; Li, Y; Tang, B; Bordag, N; Guntur, D; Enyedi, P; Olschewski, H; Olschewski, A Potassium Channels in the Transition from Fetal to the Neonatal Pulmonary Circulation.
Int J Mol Sci. 2022; 23(9): Doi: 10.3390/ijms23094681 [OPEN ACCESS]
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Review

** Atallah, R; Olschewski, A; Heinemann, A Succinate at the Crossroad of Metabolism and Angiogenesis: Roles of SDH, HIF1 alpha and SUCNR1
BIOMEDICINES. 2022; 10(12): 3089 Doi: 10.3390/biomedicines10123089 [OPEN ACCESS]
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** Sinha, M; Zabini, D; Guntur, D; Nagaraj, C; Enyedi, P; Olschewski, H; Kuebler, WM; Olschewski, A Chloride channels in the lung: Challenges and perspectives for viral infections, pulmonary arterial hypertension, and cystic fibrosis.
Pharmacol Ther. 2022; 237:108249 Doi: 10.1016/j.pharmthera.2022.108249
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Abstract (Journal)

** Birnhuber, A; Biasin, V; Jain, P; Boiarina, E; Nagaraj, C; Olschewski, A; Witzenrath, M; Marsh, LM; Tabeling, C; Kwapiszewska, G Th2-mediated pulmonary vascular hyperresponsiveness and remodelling in a mouse model of systemic sclerosis associated pulmonary arterial hypertension
WIEN KLIN WOCHENSCHR. 2022; 134(19-20):725-725.-Jahrestagung der Österreichischen Gesellschaft für Pneumologie; Salzburg, AUSTRIA. [Poster]
Web of Science

 

** Rittchen, S; Crnkovic, S; Jandl, K; Zabini, D; Mutgan, AC; Boehm, P; Hoetzenecker, K; Toller, W; Veith, C; Heinemann, A; Schermuly, RT; Olschewski, A; Marsh, LM; Kwapiszewska, G The ephrin-b2/EphB4 guidance system in pulmonary artery smooth muscle cells plays a central role in adult vascular remodeling
EUR RESPIR J. 2022; 60: Doi: 10.1183/13993003.congress-2022.2086 [Poster]
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2021

Full paper/article (Journal)

** Galhuber, M; Kupper, N; Dohr, G; Gauster, M; Kwapiszewska, G; Olschewski, A; Jandl, K; Gschwandtner, E; Schweiger, M; Kratky, D; Leitinger, G; Prokesch, A; Kolb, D Simple method of thawing cryo-stored samples preserves ultrastructural features in electron microscopy.
Histochem Cell Biol. 2021; 155(5):593-603 Doi: 10.1007/s00418-020-01952-z [OPEN ACCESS]
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** Le, Ribeuz, H; To, L; Ghigna, MR; Martin, C; Nagaraj, C; Dreano, E; Rucker-Martin, C; Girerd, B; Bouligand, J; Pechoux, C; Lambert, M; Boet, A; Issard, J; Mercier, O; Hoetzenecker, K; Manoury, B; Becq, F; Burgel, PR; Cottart, CH; Olschewski, A; Sermet-Gaudelus, I; Perros, F; Humbert, M; Montani, D; Antigny, F Involvement of CFTR in the pathogenesis of pulmonary arterial hypertension.
Eur Respir J. 2021; 58(5): Doi: 10.1183/13993003.00653-2020
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** Sharma, N; Nagaraj, C; Nagy, BM; Marsh, LM; Bordag, N; Zabini, D; Wygrecka, M; Klepetko, W; Gschwandtner, E; Genové, G; Heinemann, A; Weir, EK; Kwapiszewska, G; Olschewski, H; Olschewski, A RGS5 Determines Neutrophil Migration in the Acute Inflammatory Phase of Bleomycin-Induced Lung Injury.
Int J Mol Sci. 2021; 22(17): Doi: 10.3390/ijms22179342 [OPEN ACCESS]
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** Tabeling, C; Wienhold, SM; Birnhuber, A; Brack, MC; Nouailles, G; Kershaw, O; Firsching, TC; Gruber, AD; Lienau, J; Marsh, LM; Olschewski, A; Kwapiszewska, G; Witzenrath, M Pulmonary fibrosis in Fra-2 transgenic mice is associated with decreased numbers of alveolar macrophages and increased susceptibility to pneumococcal pneumonia.
Am J Physiol Lung Cell Mol Physiol. 2021; 320(5):L916-L925 Doi: 10.1152/ajplung.00505.2020
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Review

** Guntur, D; Olschewski, H; Enyedi, P; Csáki, R; Olschewski, A; Nagaraj, C Revisiting the Large-Conductance Calcium-Activated Potassium (BKCa) Channels in the Pulmonary Circulation.
Biomolecules. 2021; 11(11): Doi: 10.3390/biom11111629 [OPEN ACCESS]
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Abstract (Journal)

** Chandran, N; Nagy, BM; Kathrin, E; Klepetko, W; Kwapiszewska, G; Olschewski, A Role of Glucagon-Like Peptide-1 Receptor in Pulmonary Circulation
AM J RESP CRIT CARE. 2021; 203(9):May 14-19, 2021; USA. [Oral Communication]
Web of Science

 

** Foris, V; Mutgan, CA; Borenich, A; Kovacs, G; Douschan, P; Sassmannn, T; Zeder, K; Olschewski, A; Kwapiszewska, G; Olschewski, H Dehydroepiandrosterone and GDF-15 for follow-up of patients with pulmonary arterial hypertension
EUR RESPIR J. ERS International Congress 2021 abstracts. 2021; 58: -ERS International Congress; SEP 5-8, 2021; Virtuell. Doi: 10.1183/13993003.congress-2021.OA144 [Poster]
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** Mutgan, AC; Jandl, K; Marsh, L; Hoffmann, J; Gschwandtner, E; Klepetko, W; Heinemann, A; Olschewski, H; Olschewski, A; Wygrecka, M; Kwapiszewska, G Pentastatin, matrikine of the type IV collagen a5 drives pulmonary hypertension via endothelial dysfunction
EUR RESPIR J. ERS International Congress 2021 abstracts. 2021; 58: -ERS International Congress; SEP 5-8, 2021; Virtuell. Doi: 10.1183/13993003.congress-2021.PA594 [Poster]
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** Tabeling, C; Wienhold, SM; Birnhuber, A; Brack, MC; Nouailles, G; Kershaw, O; Firsching, TC; Gruber, AD; Lienau, J; Marsh, LM; Olschewski, A; Kwapiszewska, G; Witzenrath, M Pulmonary fibrosis in mice increases susceptibility to pneumococcal pneumonia and bacteremia
EUR RESPIR J. ERS International Congress 2021 abstracts. 2021; 58: -ERS International Congress; SEP 5-8, 2021; Virtuell. Doi: 10.1183/13993003.congress-2021.PA2314 [Poster]
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2020

Full paper/article (Journal)

** Biasin, V; Crnkovic, S; Sahu-Osen, A; Birnhuber, A; El Agha, E; Sinn, K; Klepetko, W; Olschewski, A; Bellusci, S; Marsh, LM; Kwapiszewska, G PDGFRα and αSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis.
Am J Physiol Lung Cell Mol Physiol. 2020; 318(4):L684-L697 Doi: 10.1152/ajplung.00128.2019 [OPEN ACCESS]
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** Hodgson, J; Swietlik, EM; Salmon, RM; Hadinnapola, C; Nikolic, I; Wharton, J; Guo, J; Liley, J; Haimel, M; Bleda, M; Southgate, L; Machado, RD; Martin, JM; Treacy, CM; Yates, K; Daugherty, LC; Shamardina, O; Whitehorn, D; Holden, S; Bogaard, HJ; Church, C; Coghlan, G; Condliffe, R; Corris, PA; Danesino, C; Eyries, M; Gall, H; Ghio, S; Ghofrani, HA; Gibbs, JSR; Girerd, B; Houweling, AC; Howard, L; Humbert, M; Kiely, DG; Kovacs, G; Lawrie, A; MacKenzie Ross, RV; Moledina, S; Montani, D; Olschewski, A; Olschewski, H; Ouwehand, WH; Peacock, AJ; Pepke-Zaba, J; Prokopenko, I; Rhodes, CJ; Scelsi, L; Seeger, W; Soubrier, F; Suntharalingam, J; Toshner, MR; Trembath, RC; Noordegraaf, AV; Wort, SJ; Wilkins, MR; Yu, PB; Li, W; Gräf, S; Upton, PD; Morrell, NW Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension.
Am J Respir Crit Care Med. 2020; 201(5):575-585 Doi: 10.1164/rccm.201906-1141OC [OPEN ACCESS]
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** Jandl, K; Marsh, LM; Hoffmann, J; Mutgan, AC; Baum, O; Bloch, W; Thekkekara-Puthenparampil, H; Kolb, D; Sinn, K; Klepetko, W; Heinemann, A; Olschewski, A; Olschewski, H; Kwapiszewska, G Basement Membrane Remodeling Controls Endothelial Function in Idiopathic Pulmonary Arterial Hypertension.
Am J Respir Cell Mol Biol. 2020; 63(1):104-117 Doi: 10.1165/rcmb.2019-0303OC
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** Skofic Maurer, D; Zabini, D; Nagaraj, C; Sharma, N; Lengyel, M; Nagy, BM; Frank, S; Klepetko, W; Gschwandtner, E; Enyedi, P; Kwapiszewska, G; Olschewski, H; Olschewski, A Endothelial Dysfunction Following Enhanced TMEM16A Activity in Human Pulmonary Arteries.
Cells. 2020; 9(9): Doi: 10.3390/cells9091984 [OPEN ACCESS]
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** Thaventhiran, JED; Lango Allen, H; Burren, OS; Rae, W; Greene, D; Staples, E; Zhang, Z; Farmery, JHR; Simeoni, I; Rivers, E; Maimaris, J; Penkett, CJ; Stephens, J; Deevi, SVV; Sanchis-Juan, A; Gleadall, NS; Thomas, MJ; Sargur, RB; Gordins, P; Baxendale, HE; Brown, M; Tuijnenburg, P; Worth, A; Hanson, S; Linger, RJ; Buckland, MS; Rayner-Matthews, PJ; Gilmour, KC; Samarghitean, C; Seneviratne, SL; Sansom, DM; Lynch, AG; Megy, K; Ellinghaus, E; Ellinghaus, D; Jorgensen, SF; Karlsen, TH; Stirrups, KE; Cutler, AJ; Kumararatne, DS; Chandra, A; Edgar, JDM; Herwadkar, A; Cooper, N; Grigoriadou, S; Huissoon, AP; Goddard, S; Jolles, S; Schuetz, C; Boschann, F; Primary Immunodeficiency Consortium for the NIHR Bioresource; Lyons, PA; Hurles, ME; Savic, S; Burns, SO; Kuijpers, TW; Turro, E; Ouwehand, WH; Thrasher, AJ; Smith, KGC Whole-genome sequencing of a sporadic primary immunodeficiency cohort.
Nature. 2020; 583(7814): 90-95. Doi: 10.1038/s41586-020-2265-1 [OPEN ACCESS]
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** Turro, E; Astle, WJ; Megy, K; Gräf, S; Greene, D; Shamardina, O; Allen, HL; Sanchis-Juan, A; Frontini, M; Thys, C; Stephens, J; Mapeta, R; Burren, OS; Downes, K; Haimel, M; Tuna, S; Deevi, SVV; Aitman, TJ; Bennett, DL; Calleja, P; Carss, K; Caulfield, MJ; Chinnery, PF; Dixon, PH; Gale, DP; James, R; Koziell, A; Laffan, MA; Levine, AP; Maher, ER; Markus, HS; Morales, J; Morrell, NW; Mumford, AD; Ormondroyd, E; Rankin, S; Rendon, A; Richardson, S; Roberts, I; Roy, NBA; Saleem, MA; Smith, KGC; Stark, H; Tan, RYY; Themistocleous, AC; Thrasher, AJ; Watkins, H; Webster, AR; Wilkins, MR; Williamson, C; Whitworth, J; Humphray, S; Bentley, DR; NIHR BioResource for the 100,000 Genomes Project; Kingston, N; Walker, N; Bradley, JR; Ashford, S; Penkett, CJ; Freson, K; Stirrups, KE; Raymond, FL; Ouwehand, WH Whole-genome sequencing of patients with rare diseases in a national health system.
Nature. 2020; 583(7814): 96-102. Doi: 10.1038/s41586-020-2434-2 [OPEN ACCESS]
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Short report/Letter

** Nagy, BM; Kovacs, G; Tornyos, A; Svehlikova, E; Foris, V; Nagaraj, C; Kwapiszewska, G; Pieber, TR; Olschewski, A; Olschewski, H No indication of insulin resistance in idiopathic pulmonary arterial hypertension with preserved physical activity.
Eur Respir J. 2020; 55(6): Doi: 10.1183/13993003.01228-2019
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** Olschewski, A; Nagaraj, C; Zabini, D; Nagy, BM; Kwapiszewska, G; Olschewski, H TMEM16A Potentiation: Possible Drawbacks.
Am J Respir Crit Care Med. 2020; 202(6):904-905 Doi: 10.1164/rccm.202004-0887LE [OPEN ACCESS]
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Correction

** Thaventhiran, JED; Lango Allen, H; Burren, OS; Rae, W; Greene, D; Staples, E; Zhang, Z; Farmery, JHR; Simeoni, I; Rivers, E; Maimaris, J; Penkett, CJ; Stephens, J; Deevi, SVV; Sanchis-Juan, A; Gleadall, NS; Thomas, MJ; Sargur, RB; Gordins, P; Baxendale, HE; Brown, M; Tuijnenburg, P; Worth, A; Hanson, S; Linger, RJ; Buckland, MS; Rayner-Matthews, PJ; Gilmour, KC; Samarghitean, C; Seneviratne, SL; Sansom, DM; Lynch, AG; Megy, K; Ellinghaus, E; Ellinghaus, D; Jorgensen, SF; Karlsen, TH; Stirrups, KE; Cutler, AJ; Kumararatne, DS; Chandra, A; Edgar, JDM; Herwadkar, A; Cooper, N; Grigoriadou, S; Huissoon, AP; Goddard, S; Jolles, S; Schuetz, C; Boschann, F; Primary Immunodeficiency Consortium for the NIHR Bioresource; Lyons, PA; Hurles, ME; Savic, S; Burns, SO; Kuijpers, TW; Turro, E; Ouwehand, WH; Thrasher, AJ; Smith, KGC Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort.
Nature. 2020; 584(7819): E2-E2. Doi: 10.1038/s41586-020-2556-6 [OPEN ACCESS]
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Abstract (Journal)

** Biasin, V; Crnkovic, S; Sahu-Osen, A; Birnhuber, A; El Agha, E; Sinn, K; Klepetko, W; Olschewski, A; Bellusci, S; Marsh, LM; Kwapiszewska, G PDGFRa and aSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis.
EUR RESPIR J. 2020; 56: Doi: 10.1183/13993003.congress-2020.3374 [Poster]
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** Birnhuber, A; Crnkovic, S; Marsh, LM; Biasin, V; Wilhelm, J; Graninger, W; Olschewski, A; Olschewski, H; Kwapiszewska, G Exacerbated Lung Function and Eosinophilic Inflammation After Blockage of Innate Immune Signalling in a Mouse Model of Systemic Sclerosis-Associated Lung Fibrosis.
AM J RESP CRIT CARE. 2020; 201: -International Conference of the American-Thoracic-Society; 2020; ELECTR NETWORK. [Onlinepräsentation]
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** Chandran, N; Nagy, BM; Sharma, N; Wollin, SL; Gschwandtner, E; Klepetko, W; Olschewski, A; Kwapiszewska, G; Olschewski, H Synergistic Effects of Nintedanib and Sildenafil on the Pulmonary Vasculature.
AM J RESP CRIT CARE. Abstract Issue ATS 2020 International Conference. 2020; 201: -International Conference of the American-Thoracic-Society; MAY 15-20, 2020; Philadelphia, US. [Poster]
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** Crnkovic, S; Biasin, V; Osen, AS; Birnhuber, A; El Agha, E; Sinn, K; Klepetko, W; Olschewski, A; Bellusci, S; Marsh, LM; Kwapiszewska, G Compartment-Specific Remodeling in Pulmonary Fibrosis Is Characterized by Involvement of Two Distinct Mesenchymal Cell Lineages.
AM J RESP CRIT CARE. 2020; 201: -International Conference of the American-Thoracic-Society; 2020; ELECTR NETWORK. [Poster]
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** Jandl, K; Marsh, LM; Hoffmann, J; Mutgan, AC; Baum, O; Bloch, W; Sinn, K; Klepetko, W; Heinemann, A; Olschewski, A; Olschewski, H; Kwapiszewska, G Basement membrane, a specialized extracellular matrix, shapes endothelial function in IPAH.
EUR RESPIR J. 2020; 56: Doi: 10.1183/13993003.congress-2020.1488 [Poster]
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** Maurer, DS; Zabini, D; Nagaraj, C; Sharma, N; Lengyel, M; Nagy, BM; Frank, S; Klepetko, W; Gschwandtner, E; Enyedi, P; Kwapiszewska, G; Olschewski, H; Olschewski, A Endothelial dysfunction following enhanced TMEM16A activity in human pulmonary arteries.
WIEN KLIN WOCHENSCHR. 2020; 132(19-20):623-624.-Jahrestagung der ÖGP; OKTOBER 14-16, 2020; GRAZ. [Oral Communication]
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** Nagy, B; Kovacs, G; Tornyos, A; Svehlikova, E; Foris, V; Nagaraj, C; Kwapiszewska, G; Pieber, TR; Olschewski, A; Olschewski, H No indication of insulin resistance in idiopathic PAH with preserved physical activity.
EUR RESPIR J. 2020; 56: Doi: 10.1183/13993003.congress-2020.1496 [Poster]
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** Nagy, BM; Kovacs, G; Tornyos, A; Svehlikova, E; Foris, V; Nagaraj, C; Kwapiszewska, G; Pieber, TR; Olschewski, A; Olschewski, H No indication of insulin resistance in idiopathic PAH with preserved physical activity.
WIEN KLIN WOCHENSCHR. 2020; 132(19-20):619-619. [Poster]
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** Sharma, N; Chandran, N; Nagy, BM; Marsh, LM; Bordag, N; Zabini, D; Klepetko, W; Gschwandtner, E; Genove, G; Heinemann, A; Weir, EK; Kwapiszewska, G; Olschewski, H; Olschewski, A Neutrophil recruitment in the acute inflammatory phase of interstitial lung disease is determined by RGS5.
WIEN KLIN WOCHENSCHR. 2020; 132(19-20):623-623.-44. Jahrestagung der ÖGP; 14.-16.10.2020; Virtuell. [Poster]
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2019

Full paper/article (Journal)

** Birnhuber, A; Crnkovic, S; Biasin, V; Marsh, LM; Odler, B; Sahu-Osen, A; Stacher-Priehse, E; Brcic, L; Schneider, F; Cikes, N; Ghanim, B; Klepetko, W; Graninger, W; Allanore, Y; Eferl, R; Olschewski, A; Olschewski, H; Kwapiszewska, G IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis.
Eur Respir J. 2019; 54(3): Doi: 10.1183/13993003.00154-2019 [OPEN ACCESS]
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** Crnkovic, S; Egemnazarov, B; Damico, R; Marsh, LM; Nagy, BM; Douschan, P; Atsina, K; Kolb, TM; Mathai, SC; Hooper, JE; Ghanim, B; Klepetko, W; Fruhwald, F; Lassner, D; Olschewski, A; Olschewski, H; Hassoun, PM; Kwapiszewska, G Disconnect between Fibrotic Response and Right Ventricular Dysfunction.
Am J Respir Crit Care Med. 2019; 199(12):1550-1560 Doi: 10.1164/rccm.201809-1737OC [OPEN ACCESS]
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** Humbert, M; Guignabert, C; Bonnet, S; Dorfmüller, P; Klinger, JR; Nicolls, MR; Olschewski, AJ; Pullamsetti, SS; Schermuly, RT; Stenmark, KR; Rabinovitch, M Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives.
Eur Respir J. 2019; 53(1): Doi: 10.1183/13993003.01887-2018 [OPEN ACCESS]
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** Jandl, K; Thekkekara Puthenparampil, H; Marsh, LM; Hoffmann, J; Wilhelm, J; Veith, C; Sinn, K; Klepetko, W; Olschewski, H; Olschewski, A; Brock, M; Kwapiszewska, G Long non-coding RNAs influence the transcriptome in pulmonary arterial hypertension: the role of PAXIP1-AS1.
J Pathol. 2019; 247(3):357-370 Doi: 10.1002/path.5195 [OPEN ACCESS]
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** Mohan, T; Nagaraj, C; Nagy, BM; Bračič, M; Maver, U; Olschewski, A; Stana Kleinschek, K; Kargl, R Nano- and Micropatterned Polycaprolactone Cellulose Composite Surfaces with Tunable Protein Adsorption, Fibrin Clot Formation, and Endothelial Cellular Response.
Biomacromolecules. 2019; 20(6): 2327-2337. Doi: 10.1021/acs.biomac.9b00304 [OPEN ACCESS]
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** Papp, R; Nagaraj, C; Zabini, D; Nagy, BM; Lengyel, M; Skofic Maurer, D; Sharma, N; Egemnazarov, B; Kovacs, G; Kwapiszewska, G; Marsh, LM; Hrzenjak, A; Höfler, G; Didiasova, M; Wygrecka, M; Sievers, LK; Szucs, P; Enyedi, P; Ghanim, B; Klepetko, W; Olschewski, H; Olschewski, A Targeting TMEM16A to reverse vasoconstriction and remodelling in idiopathic pulmonary arterial hypertension.
Eur Respir J. 2019; 53(6): 1800965 Doi: 10.1183/13993003.00965-2018
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** Rhodes, CJ; Batai, K; Bleda, M; Haimel, M; Southgate, L; Germain, M; Pauciulo, MW; Hadinnapola, C; Aman, J; Girerd, B; Arora, A; Knight, J; Hanscombe, KB; Karnes, JH; Kaakinen, M; Gall, H; Ulrich, A; Harbaum, L; Cebola, I; Ferrer, J; Lutz, K; Swietlik, EM; Ahmad, F; Amouyel, P; Archer, SL; Argula, R; Austin, ED; Badesch, D; Bakshi, S; Barnett, C; Benza, R; Bhatt, N; Bogaard, HJ; Burger, CD; Chakinala, M; Church, C; Coghlan, JG; Condliffe, R; Corris, PA; Danesino, C; Debette, S; Elliott, CG; Elwing, J; Eyries, M; Fortin, T; Franke, A; Frantz, RP; Frost, A; Garcia, JGN; Ghio, S; Ghofrani, HA; Gibbs, JSR; Harley, J; He, H; Hill, NS; Hirsch, R; Houweling, AC; Howard, LS; Ivy, D; Kiely, DG; Klinger, J; Kovacs, G; Lahm, T; Laudes, M; Machado, RD; MacKenzie Ross, RV; Marsolo, K; Martin, LJ; Moledina, S; Montani, D; Nathan, SD; Newnham, M; Olschewski, A; Olschewski, H; Oudiz, RJ; Ouwehand, WH; Peacock, AJ; Pepke-Zaba, J; Rehman, Z; Robbins, I; Roden, DM; Rosenzweig, EB; Saydain, G; Scelsi, L; Schilz, R; Seeger, W; Shaffer, CM; Simms, RW; Simon, M; Sitbon, O; Suntharalingam, J; Tang, H; Tchourbanov, AY; Thenappan, T; Torres, F; Toshner, MR; Treacy, CM; Vonk Noordegraaf, A; Waisfisz, Q; Walsworth, AK; Walter, RE; Wharton, J; White, RJ; Wilt, J; Wort, SJ; Yung, D; Lawrie, A; Humbert, M; Soubrier, F; Trégouët, DA; Prokopenko, I; Kittles, R; Gräf, S; Nichols, WC; Trembath, RC; Desai, AA; Morrell, NW; Wilkins, MR; UK NIHR BioResource Rare Diseases Consortium; UK PAH Cohort Study Consortium; US PAH Biobank Consortium Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.
Lancet Respir Med. 2019; 7(3):227-238 Doi: 10.1016/S2213-2600(18)30409-0 [OPEN ACCESS]
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** Rosenkranz, S; Diller, GP; Dumitrescu, D; Ewert, R; Ghofrani, HA; Grünig, E; Halank, M; Held, M; Kaemmerer, H; Klose, H; Kovacs, G; Konstantinides, S; Lang, IM; Lange, TJ; Leuchte, H; Mayer, E; Olschewski, A; Olschewski, H; Olsson, KM; Opitz, C; Schermuly, RT; Seeger, W; Wilkens, H; Hoeper, MM [Hemodynamic Definition of Pulmonary Hypertension: Commentary on the Proposed Change by the 6th World Symposium on Pulmonary Hypertension].
Dtsch Med Wochenschr. 2019; 144(19):1367-1372 Doi: 10.1055/a-0918-3772 [OPEN ACCESS]
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** Wei, W; Tuna, S; Keogh, MJ; Smith, KR; Aitman, TJ; Beales, PL; Bennett, DL; Gale, DP; Bitner-Glindzicz, MAK; Black, GC; Brennan, P; Elliott, P; Flinter, FA; Floto, RA; Houlden, H; Irving, M; Koziell, A; Maher, ER; Markus, HS; Morrell, NW; Newman, WG; Roberts, I; Sayer, JA; Smith, KGC; Taylor, JC; Watkins, H; Webster, AR; Wilkie, AOM; Williamson, C; NIHR BioResource–Rare Diseases; 100,000 Genomes Project–Rare Diseases Pilot; Ashford, S; Penkett, CJ; Stirrups, KE; Rendon, A; Ouwehand, WH; Bradley, JR; Raymond, FL; Caulfield, M; Turro, E; Chinnery, PF Germline selection shapes human mitochondrial DNA diversity.
Science. 2019; 364(6442): Doi: 10.1126/science.aau6520 [OPEN ACCESS]
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Abstract (Journal)

** Birnhuber, A; Crnkovic, S; Marsh, LM; Biasin, V; Graninger, W; Olschewski, A; Olschewski, H; Kwapiszewska, G Targeting innate immunity exacerbates inflammation and pulmonary fibrosis in a systemic sclerosis-associated lung disease model
WIEN KLIN WOCHENSCHR. 2019; 131(19-20):512-512. [Oral Communication]
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** Bruni, C; Occhipinti, M; Camiciottoli, G; Bartolucci, M; Pienn, M; Lepri, G; Fabbrizzi, A; Tottoli, A; Ciardi, G; Giuggioli, D; Cuomo, G; Masini, F; Olschewski, A; Lavorini, F; Colagrande, S; Matucci-Cerinic, M Relationship Between Parenchymal and Vascular Features in Systemic Sclerosis-Interstitial Lung Disease: Results from Quantitative Analysis of Chest Computed Tomography
ARTHRITIS RHEUMATOL. 2019; 71: [Poster]
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** Chandran, N; Sharma, N; Wollin, L; Olschewski, A; Kwapiszewska, G; Olschewski, H Nintedanib has acute pulmonary vasodilatory effects in transgenic Fra2 mice with spontaneous progressive pulmonary hypertension and lung fibrosis
EUR RESPIR J. 2019; 54: -European-Respiratory-Society (ERS) International Congress; SEP 28-OCT 02, 2019; Madrid, SPAIN. Doi: 10.1183/13993003.congress-2019.PA5382 [Poster]
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** Chandran, N; Sharma, N; Wollin, SL; Olschewski, A; Kwapiszewska, G; Olschewski, H The Effect of Nintedanib on Pulmonary Vascular Tone in an Experimental Model of Lung Fibrosis and Pulmonary Hypertension
AM J RESP CRIT CARE. 2019; 199: -International Conference of the American-Thoracic-Society; MAY 17-22, 2019; Dallas, TX. [Poster]
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** Jandl, K; Klepetko, W; Kwapiszewska, G; Marsh, LM; Olschewski, A; Sinn, K; Zabini, D; Crnkovic, S Adult pulmonary vascular remodeling is independent of ephrin-b2/EphB4 guidance system
WIEN KLIN WOCHENSCHR. 2019; 131(19-20):512-513. [Poster]
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** Kwapiszewska, G; Gungl, A; Wilhelm, J; Marsh, LM; Puthenparampil, HT; Sinn, K; Didiasova, M; Klepetko, W; Kosanovic, D; Schermuly, RT; Wujak, L; Weiss, B; Schaefer, L; Schneider, M; Kreuter, M; Olschewski, A; Seeger, W; Olschewski, H; Wygrecka, M Transcriptome profiling reveals the complexity of pirfenidone effects in IPF
EUR RESPIR J. 2019; 54: -European-Respiratory-Society (ERS) International Congress; SEP 28-OCT 02, 2019; Madrid, SPAIN. Doi: 10.1183/13993003.congress-2019.PA1280 [Poster]
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** Mutgan, AC; Jandl, K; Hoffmann, J; Klepetko, W; Kovacs, G; Olschewski, H; Olschewski, A; Kwapiszewska, G Fragment of Collagen IV is a mediator of endothelial dysfunction in pulmonary hypertension
WIEN KLIN WOCHENSCHR. 2019; 131(19-20):511-511. [Oral Communication]
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** Nagaraj, C; Sharma, N; Nagy, B; Junien, JL; Broqua, P; Konstantinova, I; Olschewski, A; Kwapiszewska, G; Olschewski, H IMPACT OF LANIFIBRANOR, A PAN-PPAR AGONIST, ON THE PULMONARY VASCULAR TONE
ANN RHEUM DIS. 2019; 78: 452-452.-Annual European Congress of Rheumatology (EULAR); JUN 12-15, 2019; Madrid, SPAIN. Doi: 10.1136/annrheumdis-2019-eular.4003 [Poster] [OPEN ACCESS]
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** Nagy, BM; Kovacs, G; Tornyos, A; Svehlikova, E; Foris, V; Nagaraj, C; Kwapiszewska, G; Pieber, TR; Olschewski, A; Olschewski, H Is idiopathic pulmonary arterial hypertension caused by insulin resistance?
WIEN KLIN WOCHENSCHR. 2019; 131(19-20):526-526. [Oral Communication]
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2018

Full paper/article (Journal)

** Biasin, V; Wygrecka, M; Bärnthaler, T; Jandl, K; Jain, PP; Bálint, Z; Kovacs, G; Leitinger, G; Kolb-Lenz, D; Kornmueller, K; Peters, F; Sinn, K; Klepetko, W; Heinemann, A; Olschewski, A; Becker-Pauly, C; Kwapiszewska, G Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation.
Thromb Haemost. 2018; 118(10):1790-1802 Doi: 10.1055/s-0038-1670657
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** Crnkovic, S; Marsh, LM; El Agha, E; Voswinckel, R; Ghanim, B; Klepetko, W; Stacher-Priehse, E; Olschewski, H; Bloch, W; Bellusci, S; Olschewski, A; Kwapiszewska, G Resident cell lineages are preserved in pulmonary vascular remodeling.
J Pathol. 2018; 244(4):485-498 Doi: 10.1002/path.5044 [OPEN ACCESS]
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** Douschan, P; Kovacs, G; Avian, A; Foris, V; Gruber, F; Olschewski, A; Olschewski, H Mild Elevation of Pulmonary Arterial Pressure as a Predictor of Mortality.
Am J Respir Crit Care Med. 2018; 197(4):509-516 Doi: 10.1164/rccm.201706-1215OC
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** Fazakas, C; Nagaraj, C; Zabini, D; Végh, AG; Marsh, LM; Wilhelm, I; Krizbai, IA; Olschewski, H; Olschewski, A; Bálint, Z Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension.
Front Physiol. 2018; 9:537-537 Doi: 10.3389/fphys.2018.00537 [OPEN ACCESS]
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** Frille, A; Leithner, K; Olschewski, A; Olschewski, H; Wohlkönig, C; Hrzenjak, A No erythropoietin-induced growth is observed in non-small cell lung cancer cells.
Int J Oncol. 2018; 52(2): 518-526. Doi: 10.3892/ijo.2017.4225 [OPEN ACCESS]
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** Gräf, S; Haimel, M; Bleda, M; Hadinnapola, C; Southgate, L; Li, W; Hodgson, J; Liu, B; Salmon, RM; Southwood, M; Machado, RD; Martin, JM; Treacy, CM; Yates, K; Daugherty, LC; Shamardina, O; Whitehorn, D; Holden, S; Aldred, M; Bogaard, HJ; Church, C; Coghlan, G; Condliffe, R; Corris, PA; Danesino, C; Eyries, M; Gall, H; Ghio, S; Ghofrani, HA; Gibbs, JSR; Girerd, B; Houweling, AC; Howard, L; Humbert, M; Kiely, DG; Kovacs, G; MacKenzie Ross, RV; Moledina, S; Montani, D; Newnham, M; Olschewski, A; Olschewski, H; Peacock, AJ; Pepke-Zaba, J; Prokopenko, I; Rhodes, CJ; Scelsi, L; Seeger, W; Soubrier, F; Stein, DF; Suntharalingam, J; Swietlik, EM; Toshner, MR; van Heel, DA; Vonk Noordegraaf, A; Waisfisz, Q; Wharton, J; Wort, SJ; Ouwehand, WH; Soranzo, N; Lawrie, A; Upton, PD; Wilkins, MR; Trembath, RC; Morrell, NW Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.
Nat Commun. 2018; 9(1): 1416-1416. Doi: 10.1038/s41467-018-03672-4 [OPEN ACCESS]
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** Gungl, A; Biasin, V; Wilhelm, J; Olschewski, A; Kwapiszewska, G; Marsh, LM Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner.
Front Immunol. 2018; 9(10):2018-2018 Doi: 10.3389/fimmu.2018.02018 [OPEN ACCESS]
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** Kwapiszewska, G; Gungl, A; Wilhelm, J; Marsh, LM; Thekkekara Puthenparampil, H; Sinn, K; Didiasova, M; Klepetko, W; Kosanovic, D; Schermuly, RT; Wujak, L; Weiss, B; Schaefer, L; Schneider, M; Kreuter, M; Olschewski, A; Seeger, W; Olschewski, H; Wygrecka, M Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis.
Eur Respir J. 2018; 52(5): Doi: 10.1183/13993003.00564-2018 [OPEN ACCESS]
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** Leithner, K; Triebl, A; Trötzmüller, M; Hinteregger, B; Leko, P; Wieser, BI; Grasmann, G; Bertsch, AL; Züllig, T; Stacher, E; Valli, A; Prassl, R; Olschewski, A; Harris, AL; Köfeler, HC; Olschewski, H; Hrzenjak, A The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.
Proc Natl Acad Sci U S A. 2018; 115(24):6225-6230 Doi: 10.1073/pnas.1719871115 [OPEN ACCESS]
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** Marsh, LM; Jandl, K; Grünig, G; Foris, V; Bashir, M; Ghanim, B; Klepetko, W; Olschewski, H; Olschewski, A; Kwapiszewska, G The inflammatory cell landscape in the lungs of patients with idiopathic pulmonary arterial hypertension.
Eur Respir J. 2018; 51(1): Doi: 10.1183/13993003.01214-2017 [OPEN ACCESS]
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** Olschewski, A; Berghausen, EM; Eichstaedt, CA; Fleischmann, BK; Grünig, E; Grünig, G; Hansmann, G; Harbaum, L; Hennigs, JK; Jonigk, D; Kuebler, WM; Kwapiszewska, G; Pullamsetti, SS; Stacher, E; Weissmann, N; Wenzel, D; Schermuly, RT Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018.
Int J Cardiol. 2018; 272S(10): 4-10. Doi: 10.1016/j.ijcard.2018.09.070 [OPEN ACCESS]
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** Pienn, M; Burgard, C; Payer, C; Avian, A; Urschler, M; Stollberger, R; Olschewski, A; Olschewski, H; Johnson, T; Meinel, FG; Bálint, Z Healthy Lung Vessel Morphology Derived From Thoracic Computed Tomography.
Front Physiol. 2018; 9(1):346-346 Doi: 10.3389/fphys.2018.00346 [OPEN ACCESS]
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** Traeger, L; Gallitz, I; Sekhri, R; Bäumer, N; Kuhlmann, T; Kemming, C; Holtkamp, M; Müller, JC; Karst, U; Canonne-Hergaux, F; Muckenthaler, MU; Bloch, DB; Olschewski, A; Bartnikas, TB; Steinbicker, AU ALK3 undergoes ligand-independent homodimerization and BMP-induced heterodimerization with ALK2.
FREE RADICAL BIO MED. 2018; 129(10): 127-137. Doi: 10.1016/j.freeradbiomed.2018.09.021 [OPEN ACCESS]
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** Zabini, D; Granton, E; Hu, Y; Miranda, MZ; Weichelt, U; Breuils Bonnet, S; Bonnet, S; Morrell, NW; Connelly, KA; Provencher, S; Ghanim, B; Klepetko, W; Olschewski, A; Kapus, A; Kuebler, WM Loss of SMAD3 Promotes Vascular Remodeling in Pulmonary Arterial Hypertension via MRTF Disinhibition.
Am J Respir Crit Care Med. 2018; 197(2):244-260 Doi: 10.1164/rccm.201702-0386OC
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Review

** Kuebler, WM; Nicolls, MR; Olschewski, A; Abe, K; Rabinovitch, M; Stewart, D; Chan, SY; Morrell, NW; Archer, SL; Spiekerkoetter, E A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017.
Am J Physiol Lung Cell Mol Physiol. 2018; 315(4):L502-L516 Doi: 10.1152/ajplung.00150.2018 [OPEN ACCESS]
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** Lambert, M; Capuano, V; Olschewski, A; Sabourin, J; Nagaraj, C; Girerd, B; Weatherald, J; Humbert, M; Antigny, F Ion Channels in Pulmonary Hypertension: A Therapeutic Interest?
INT J MOL SCI. 2018; 19(10): Doi: 10.3390/ijms19103162 [OPEN ACCESS]
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Abstract (Journal)

** Gungl, A; Slaven, C; Biasin, V; Marsh, LM; Odler, B; Sahu-Osen, A; Brcic, L; Ghanim, B; Klepetko, W; Graninger, W; Olschewski, A; Olschewski, H; Kwapiszewska, G Blockade of IL-1 signalling exacerbates Th2 inflammation in the Fra-2 transgenic mouse model of systemic sclerosis
WIEN KLIN WOCHENSCHR. 2018; 130(19-20):605-606. [Poster]
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** Jandl, K; Marsh, L; Hoffmann, J; Bloch, W; Sinn, K; Klepetko, W; Kovac, G; Olschewski, A; Olschewski, H; Kwapiszewska, G Basement membrane remodelling defines the progression of IPAH: the role of Collagen XVIIIA1*
WIEN KLIN WOCHENSCHR. 2018; 130(19-20):604-604. [Oral Communication]
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** Marsh, LM; Gungl, A; Biasin, V; Olschewski, A; Kwapiszewska, G AP-1 Subunit Overexpression Drives a Non-Allergic Asthma Phenotype in Mice
American Journal of Respiratory and Critical Care Medicine 2018;197:A1299. 2018; 197: -ATS 2018; May 18-23, 2018; San Diego, USA. [Poster]
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** Nagy, B; Bordag, N; Nagaraj, C; Foris, V; Tornyos, A; Narath, S; Gander, E; Magnes, C; Kovacs, G; Klepetko, W; Pieber, TR; Kwapiszewska, G; Olschewski, H; Olschewski, A Metabolic fingerprinting in pulmonary hypertension*
WIEN KLIN WOCHENSCHR. 2018; 130(19-20):604-605. [Oral Communication]
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** Pfeiffer, S; Avian, A; Douschan, P; Foris, V; Olschewski, A; Olschewski, H; Kovacs, G Right ventricular tissue doppler echocardiography in pulmonary hypertension
EUR RESPIR J. 2018; 52: -28th International Congress of the European-Respiratory-Society (ERS); SEP 15-19, 2018; Paris, FRANCE. Doi: 10.1183/13993003.congress-2018.PA3111 [Oral Communication]
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** Sassmann, T; Kovacs, G; Stauber, R; Foris, V; Pfeiffer, S; Gruber, F; Revelant, F; Stadlbauer, V; Kniepeiss, D; Zollner, G; Fickert, P; Avian, A; Olschewski, A; Olschewski, H; Douschan, P Diastolic dysfunction and cardiopulmonary exercise capacity in patients with advanced liver disease-results from a prospective cross-sectional cohort
WIEN KLIN WOCHENSCHR. 2018; 130(19-20):627-627.-ÖGP Jahrestagung; OKT 18-20, 2018; Linz, Austria. [Poster]
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** Sassmann, T; Kovacs, G; Stauber, RE; Revelant, F; Foris, V; Pfeiffer, S; Gruber, F; Stadlbauer, V; Kniepeiss, D; Zollner, G; Fickert, P; Avian, A; Olschewski, A; Olschewski, H; Douschan, P; Impact of diastolic dysfunction on exercise capacity in patients with liver cirrhosis
European Respiratory Journal. 2018; 52(sup 62):-ERS International Congress; SEP 15 - 19, 2018; Paris, France. Doi: 10.1183/13993003.congress-2018.PA2486 [Poster]
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** Sharma, N; Nagaraj, C; Miklos, BN; Skofic-Maurer, D; Kwapiszewska, G; Olschewski, A; Olschewski, H Impact of regulator of G protein signaling 5 in pulmonary circulation
WIEN KLIN WOCHENSCHR. . 2018; 130(19-20):605-605.-42. Jahrestagung der Österreichischen Gesellschaft für Pneumologie 2. Jahrestagung der Österreichischen Gesellschaft für Thoraxchirurgie; OCT 18-20, 2018; Linz, AUSTRIA. [Poster]
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** Tornyos, A; Trinker, M; Foris, V; Pfeiffer, S; Odler, B; Douschan, P; Avian, A; Leitner, A; Olschewski, A; Kovacs, G; Olschewski, H Pulmonary hypertension in hypersensitivity pneumonitis
WIEN KLIN WOCHENSCHR. 2018; 130(19-20):621-621.-42. Jahrestagung der Österreichischen Gesellschaft für Pneumologie 2. Jahrestagung der Österreichischen Gesellschaft für Thoraxchirurgie; OCT 18-20; Linz, AUSTRIA. [Poster]
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** Tornyos, A; Trinker, M; Foris, V; Pfeiffer, S; Odler, B; Douschan, P; Avian, A; Leitner, A; Olschewski, A; Kovacs, G; Olschewski, H Pulmonary hypertension in hypersensitivity pneumonitis.
EUR RESPIR J. 2018; 52: -28th International Congress of the European-Respiratory-Society (ERS); SEP 15-19, 2018; Paris, FRANCE. Doi: 10.1183/13993003.congress-2018.PA3100 [Poster]
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2017

Full paper/article (Journal)

** Bärnthaler, T; Maric, J; Platzer, W; Konya, V; Theiler, A; Hasenöhrl, C; Gottschalk, B; Trautmann, S; Schreiber, Y; Graier, WF; Schicho, R; Marsche, G; Olschewski, A; Thomas, D; Schuligoi, R; Heinemann, A The Role of PGE₂ in Alveolar Epithelial and Lung Microvascular Endothelial Crosstalk.
Sci Rep. 2017; 7(1):7923-7923 Doi: 10.1038/s41598-017-08228-y [OPEN ACCESS]
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** Biasin, V; Wygrecka, M; Marsh, LM; Becker-Pauly, C; Brcic, L; Ghanim, B; Klepetko, W; Olschewski, A; Kwapiszewska, G Meprin β contributes to collagen deposition in lung fibrosis.
Sci Rep. 2017; 7(1):39969-39969 Doi: 10.1038/srep39969 [OPEN ACCESS]
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** Kovacs, G; Avian, A; Wutte, N; Hafner, F; Moazedi-Fürst, F; Kielhauser, S; Aberer, E; Brodmann, M; Graninger, W; Foris, V; Olschewski, A; Olschewski, H Changes in pulmonary exercise haemodynamics in scleroderma: a 4-year prospective study.
Eur Respir J. 2017; 50(1): Doi: 10.1183/13993003.01708-2016 [OPEN ACCESS]
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** Mohan, T; Niegelhell, K; Nagaraj, C; Reishofer, D; Spirk, S; Olschewski, A; Stana Kleinschek, K; Kargl, R Interaction of Tissue Engineering Substrates with Serum Proteins and Its Influence on Human Primary Endothelial Cells.
Biomacromolecules. 2017; 18(2):413-421 Doi: 10.1021/acs.biomac.6b01504
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** Nagaraj, C; Haitchi, HM; Heinemann, A; Howarth, PH; Olschewski, A; Marsh, LM Increased Expression of p22phox Mediates Airway Hyperresponsiveness in an Experimental Model of Asthma.
Antioxid Redox Signal. 2017; 27(18):1460-1472 Doi: 10.1089/ars.2016.6863 [OPEN ACCESS]
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** Nagaraj, C; Tabeling, C; Nagy, BM; Jain, PP; Marsh, LM; Papp, R; Pienn, M; Witzenrath, M; Ghanim, B; Klepetko, W; Weir, EK; Heschl, S; Kwapiszewska, G; Olschewski, A; Olschewski, H Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox.
Eur Respir J. 2017; 50(1): Doi: 10.1183/13993003.01651-2016 [OPEN ACCESS]
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** Nagy, BM; Nagaraj, C; Egemnazarov, B; Kwapiszewska, G; Stauber, RE; Avian, A; Olschewski, H; Olschewski, A Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia.
Front Physiol. 2017; 8(8):98-98 Doi: 10.3389/fphys.2017.00098 [OPEN ACCESS]
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** Nagy, BM; Nagaraj, C; Meinitzer, A; Sharma, N; Papp, R; Foris, V; Ghanim, B; Kwapiszewska, G; Kovacs, G; Klepetko, W; Pieber, TR; Mangge, H; Olschewski, H; Olschewski, A Importance of kynurenine in pulmonary hypertension.
Am J Physiol Lung Cell Mol Physiol. 2017; 313(5):L741-L751 Doi: 10.1152/ajplung.00517.2016 [OPEN ACCESS]
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** Wohlkoenig, C; Leithner, K; Olschewski, A; Olschewski, H; Hrzenjak, A TR3 is involved in hypoxia-induced apoptosis resistance in lung cancer cells downstream of HIF-1α.
Lung Cancer. 2017; 111(3):15-22 Doi: 10.1016/j.lungcan.2017.06.013
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Review

** Olschewski, A; Veale, EL; Nagy, BM; Nagaraj, C; Kwapiszewska, G; Antigny, F; Lambert, M; Humbert, M; Czirják, G; Enyedi, P; Mathie, A TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications.
Eur Respir J. 2017; 50(5): Doi: 10.1183/13993003.00754-2017 [OPEN ACCESS]
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Abstract (Journal)

** Crnkovic, S; Egemnazarov, B; Marsh, L; Douschan, P; Ghanim, B; Klepetko, W; Fruhwald, F; Lassner, D; Olschewski, A; Olschewski, H; Kwapiszewska, G Therapy of right ventricular fibrosis does not ameliorate right ventricular dysfunction
WIEN KLIN WOCHENSCHR. 2017; 129(19-20):756-756. [Keynote lecture]
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** Crnkovic, S; Marsh, LM; El Agha, E; Voswinckel, R; Ghanim, B; Klepetko, W; Stacher-Priehse, E; Bloch, W; Olschewski, H; Bellusci, S; Olschewski, A; Kwapiszewska, G Expansion Of Resident Smooth Muscle Cells Marks The Remodeling Process In The Pulmonary Vasculature
AM J RESP CRIT CARE. 2017; 195: -International Conference of the American-Thoracic-Society (ATS); MAY 19-24, 2017; Washington, USA. [Oral Communication]
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** Douschan, P; Kovacs, G; Stadlbauer, V; Kniepeiss, D; Krones, E; Durchschein, F; Rainer, F; Spindelboeck, W; Wagner, M; Zollner, G; Avian, A; Fickert, P; Olschewski, A; Olschewski, H; Stauber, RE Exercise capacity and exercise hemodynamics in the screening for pulmonary vascular disease (PVD) in patients with portal hypertension - results from a prospective cross-sectional study
J HEPATOL. 2017; 66(1):S568-S569.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)31556-8 [Poster]
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** Douschan, P; Kovacs, G; Stauber, R; Foris, V; Pfeiffer, S; Gruber, F; Sassmann, T; Revelant, F; Stadlbauer, V; Kniepeiss, D; Fickert, P; Avian, A; Olschewski, A; Olschewski, H Impact of chronic liver disease on pulmonary hemodynamics and exercise tolerance - results from a prospective cross-sectional study
WIEN KLIN WOCHENSCHR. 2017; 129(19-20):768-769. [Poster]
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** Douschan, P; Kovacs, G; Stauber, R; Foris, V; Pfeiffer, S; Gruber, F; Stadlbauer-Kollner, V; Kniepeiss, D; Zollner, G; Fickert, P; Avian, A; Olschewski, A; Olschewski, H Exercise Hemodynamics In The Screening For Pulmonary Vascular Disease In Patients With Portal Hypertension - Results From A Prospective Cross-Sectional Study
AM J RESP CRIT CARE. 2017; 195: -International Conference of the American-Thoracic-Society (ATS); MAY 19-24, 2017; Washington, USA. [Oral Communication]
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** Giuliani, N; Urschler, M; Olschewski, A; Olschewski, H; Pienn, M Fully-automatic lung fissure detection from thoracic computed tomography images
WIEN KLIN WOCHENSCHR. 2017; 129(19-20):767-767.-41. Jahrestagung der Österreichischen Gesellschaft für Pneumologie und 1. Jahrestagung der Österreichischen Gesellschaft für Thoraxchirurgie; OCT 5–7, 2017; Innsbruck, AUSTRIA. [Poster]
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** Gungl, A; Crnkovic, S; Biasin, V; Marsh, LM; Sahu-Osen, A; Stacher-Priehse, E; Brcic, L; Schneider, F; Cikes, N; Ghanim, B; Klepetko, W; Odler, B; Kovacs, G; Eferl, R; Olschewski, H; Olschewski, A; Kwapiszewska, G Fos-Related Antigen 2 (fra-2)-Driven Interleukin-1 Expression Leads To Pulmonary Remodelling Via Interleukin-6 And Tenascin C In Systemic Sclerosis
AM J RESP CRIT CARE. 2017; 195: -International Conference of the American-Thoracic-Society (ATS); MAY 19-24, 2017; Washington, USA. [Oral Communication]
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** Jandl, K; Hoffmann, J; Marsh, LM; Bloch, W; Thekkekara Puthenparampil, H; Ghanim, B; Klepetko, W; Kovacs, G; Olschewski, A; Olschewski, H; Kwapiszewska, G Influence Of Colxviiia1 Fragment, Endostatin, On Endothelial Cells In Idiopathic Pulmonary Hypertension
Am J Respir Crit Care Med 2017;. 2017; 195(A2243):-American Thoracic Society; May 19-24, 2017; Washington, USA. [Poster]
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** Marsh, LM; Jandl, K; Bashir, M; Ghanim, B; Klepetko, W; Foris, V; Olschewski, H; Olschewski, A; Kwapiszewska, G Idiopathic Pulmonary Arterial Hypertension Lungs Possess Distinct Inflammatory Profiles
AM J RESP CRIT CARE. 2017; 195: -International Conference of the American-Thoracic-Society (ATS); MAY 19-24, 2017; Washington, USA. [Poster]
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** Nagy, B; Nagaraj, C; Meinitzer, A; Papp, R; Foris, V; Ghanim, B; Kwapiszewska, G; Kovacs, G; Klepetko, W; Pieber, TR; Mangge, H; Olschewski, H; Olschewski, A An intrinsic tryptophan metabolite acts as pulmonary vasodilator in pulmonary hypertension
FASEB J. 2017; 31: -Annual Meeting of the American-Society-for-Pharmacology-and-Experimental-Therapeutics (ASPET) at Experimental Biology Meeting; APR 22-26, 2017; Chicago, IL. [Oral Communication]
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** Odler, B; Reiter, U; Reiter, G; Fuchsjaeger, M; Foris, V; Tornyos, A; Douschan, P; Olschewski, A; Olschewski, H; Kovacs, G Cardiac magnetic resonance parameters in the assessment of pulmonary hemodynamics: a validation study
WIEN KLIN WOCHENSCHR. 2017; 129(19-20):768-768.SEPT ; Milan, ITALY. [Poster]
Web of Science

 

** Olschewski, A; Papp, R; Nagaraj, C; Nagy, B; Balint, Z; Kwapiszewska, G; Stacher-Priehse, E; Kovacs, G; Klepetko, W; Ghanim, B; Wygrecka, M; Didiasova, M; Olschewski, H Targeting Tmem16a Might Represent A Novel Reverse Remodeling Therapy In Pulmonary Arterial Hypertension
AM J RESP CRIT CARE. 2017; 195: -International Conference of the American-Thoracic-Society (ATS); MAY 19-24, 2017; Washington, USA. [Poster]
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** Pienn, M; Burgard, C; Payer, C; Urschler, M; Johnson, T; Stollberger, R; Olschewski, A; Olschewski, H; Meinel, FG; Balint, Z Age-related changes in lung vessel morphology in healthy men and women
WIEN KLIN WOCHENSCHR. 2017; 129(19-20):756-756.-41. Jahrestagung der Österreichischen Gesellschaft für Pneumologie und 1. Jahrestagung der Österreichischen Gesellschaft für Thoraxchirurgie; OCT 5–7, 2017; Innsbruck, AUSTRIA. [Poster]
Web of Science

 

** Puthenparampil, HT; Jandl, K; Wilhelm, J; Hoffmann, J; Marsh, L; Klepetko, W; Olschewski, A; Brock, M; Kwapiszewska, G Differentially expressed lncRNAs in IPAH: the impact of PAXIP1-AS1 on hPASMCs function
WIEN KLIN WOCHENSCHR. .. 2017; 129(19-20):755-755. [Poster]
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2016

Full paper/article (Journal)

** Crnkovic, S; Schmidt, A; Egemnazarov, B; Wilhelm, J; Marsh, LM; Ghanim, B; Klepetko, W; Olschewski, A; Olschewski, H; Kwapiszewska, G Functional and molecular factors associated with TAPSE in hypoxic pulmonary hypertension.
Am J Physiol Lung Cell Mol Physiol. 2016; 311(1):L59-L73 Doi: 10.1152/ajplung.00381.2015 [OPEN ACCESS]
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** Foris, V; Kovacs, G; Marsh, LM; Bálint, Z; Tötsch, M; Avian, A; Douschan, P; Ghanim, B; Klepetko, W; Olschewski, A; Olschewski, H CD133+ cells in pulmonary arterial hypertension.
Eur Respir J. 2016; 48(2):459-469 Doi: 10.1183/13993003.01523-2015 [OPEN ACCESS]
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** Jandl, K; Stacher, E; Bálint, Z; Sturm, EM; Maric, J; Peinhaupt, M; Luschnig, P; Aringer, I; Fauland, A; Konya, V; Dahlen, SE; Wheelock, CE; Kratky, D; Olschewski, A; Marsche, G; Schuligoi, R; Heinemann, A Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung.
J Allergy Clin Immunol. 2016; 137(3):833-843 Doi: 10.1016/j.jaci.2015.11.012 [OPEN ACCESS]
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** Kovacs, G; Avian, A; Foris, V; Tscherner, M; Kqiku, X; Douschan, P; Bachmaier, G; Olschewski, A; Matucci-Cerinic, M; Olschewski, H Use of ECG and Other Simple Non-Invasive Tools to Assess Pulmonary Hypertension.
PLoS One. 2016; 11(12):e0168706-e0168706 Doi: 10.1371/journal.pone.0168706 [OPEN ACCESS]
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** Leithner, K; Hirschmugl, B; Li, Y; Tang, B; Papp, R; Nagaraj, C; Stacher, E; Stiegler, P; Lindenmann, J; Olschewski, A; Olschewski, H; Hrzenjak, A TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers.
PLoS One. 2016; 11(6):e0157453-e0157453 Doi: 10.1371/journal.pone.0157453 [OPEN ACCESS]
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** Nagaraj, C; Tang, B; Nagy, BM; Papp, R; Jain, PP; Marsh, LM; Meredith, AL; Ghanim, B; Klepetko, W; Kwapiszewska, G; Weir, EK; Olschewski, H; Olschewski, A Docosahexaenoic acid causes rapid pulmonary arterial relaxation via KCa channel-mediated hyperpolarisation in pulmonary hypertension.
Eur Respir J. 2016; 48(4):1127-1136 Doi: 10.1183/13993003.01814-2015 [OPEN ACCESS]
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** Payer, C; Pienn, M; Bálint, Z; Shekhovtsov, A; Talakic, E; Nagy, E; Olschewski, A; Olschewski, H; Urschler, M Automated integer programming based separation of arteries and veins from thoracic CT images.
Med Image Anal. 2016; 34:109-122 Doi: 10.1016/j.media.2016.05.002 [OPEN ACCESS]
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** Wolff, M; Czorlich, P; Nagaraj, C; Schnöbel-Ehehalt, R; Li, Y; Kwapiszewska, G; Olschewski, H; Heschl, S; Olschewski, A Amitriptyline and carbamazepine utilize voltage-gated ion channel suppression to impair excitability of sensory dorsal horn neurons in thin tissue slice: An in vitro study.
Neurosci Res. 2016; 109(5):16-27 Doi: 10.1016/j.neures.2016.02.006
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Review

** Hoffmann, J; Wilhelm, J; Olschewski, A; Kwapiszewska, G Microarray analysis in pulmonary hypertension.
Eur Respir J. 2016; 48(1):229-241 Doi: 10.1183/13993003.02030-2015 [OPEN ACCESS]
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** Kovacs, G; Kleinschek, D; Kwapiszewska, G; Bálint, Z; Olschewski, H; Olschewski, A [Research in Austria - the Ludwig Boltzmann Institute for Lung Vascular Research].
Pneumologie. 2016; 70(5):331-335 Doi: 10.1055/s-0042-104767 [OPEN ACCESS]
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** Kwapiszewska, G; Hoffmann, J; Kovacs, G; Stacher, E; Olschewski, A; Olschewski, H [Pulmonary (Arterial) Hypertension].
Pneumologie. 2016; 70(10):630-637 Doi: 10.1055/s-0042-100537
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Correspondence

** Olschewski, A; Chandran, N; Olschewski, H Letter by Olschewski et al Regarding Article, "Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation".
Circulation. 2016; 133(11): e439-e439. Doi: 10.1161/CIRCULATIONAHA.115.018800 [OPEN ACCESS]
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Abstract (Journal)

** Chandran, N; Papp, R; Nagy, B; Ghanim, B; Klepetko, W; Olschewski, H; Olschewski, A Expressional regulation of Cytoplasmic/non-receptor tyrosine kinase Src family in pulmonary circulation
WIEN KLIN WOCHENSCHR. .. 2016; 128(19-20):762-762. [Poster]
Web of Science

 

** Crnkovic, S; Jain, P; Egemnazarov, B; Marsh, LM; Ghanim, B; Klepetko, W; Holzer, P; Herzog, H; Olschewski, A; Kwapiszewska, G Increased Expression Of Npy1r Mediated Increased Vascular Reactivity To Npy
AM J RESP CRIT CARE. .. 2016; 193: -International Conference of the American-Thoracic-Society (ATS); MAY 13-18, 2016; San Francisco, CA. [Poster]
Web of Science

 

** Douschan, P; Kovacs, G; Foris, V; Avian, A; Olschewski, A; Olschewski, H Borderline pulmonary pressure elevation is associated with worse prognosis in patients at risk for pulmonary hypertension
EUR HEART J. 2016; 37: 156-156.-Congress of the European-Society-of-Cardiology (ESC); AUG 27-31, 2016; Rome, ITALY. [Oral Communication]
Web of Science

 

** Douschan, P; Kovacs, G; Foris, V; Avian, A; Olschewski, A; Olschewski, H Borderline Pulmonary Pressure Is Associated With Worse Survival In Patients At Risk For Pulmonary Hypertension - A Retrospective Single Center Analysis
AM J RESP CRIT CARE. 2016; 193: -International Conference of the American-Thoracic-Society (ATS); MAY 13-18, 2016; San Francisco, CA. [Poster]
Web of Science

 

** Egemnazarov, BB; Crnkovic, S; Olschewski, H; Olschewski, A; Marsh, LM; Kwapiszewska, G Cartilage oligomeric matrix protein (COMP) is a potential adaptive mechanism to the pressure overload in the right ventricle
EUR J HEART FAIL. 2016; 18: 149-149. [Oral Communication]
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** Foris, V; Kovacs, G; Avian, A; Douschan, P; Olschewski, A; Olschewski, H NLR predicts prognosis in pulmonary arterial hypertension
WIEN KLIN WOCHENSCHR. 2016; 128(19-20):768-768.-ÖGP; OKT 6-8, 2016; Vienna, Austria. [Poster]
Web of Science

 

** Foris, V; Kovacs, G; Douschan, P; Avian, A; Olschewski, A; Olschewski, H Neutrophil- To-Lymphocyte Ratio Predicts Survival In Pulmonary Arterial Hypertension Patients
AM J RESP CRIT CARE. 2016; 193: -International Conference of the American-Thoracic-Society (ATS); MAY 13-18, 2016; San Francisco, CA. [Poster]
Web of Science

 

** Hoffmann, J; Ghanim, B; Klepetko, W; Kovacs, G; Olschewski, H; Olschewski, A; Kwapiszewska, G Composition And Structure Of The Vascular Basement Membrane In Pulmonary Hypertension
AM J RESP CRIT CARE. .. 2016; 193: -International Conference of the American-Thoracic-Society (ATS); MAY 13-18, 2016; San Francisco, CA. [Poster]
Web of Science

 

** Jandl, K; Hoffmann, J; Bloch, W; Ghanim, B; Klepetko, W; Kovacs, G; Olschewski, H; Olschewski, A; Kwapiszewska, G Disturbances in composition, structure and function of the vascular basement membrane in pulmonary hypertension
WIEN KLIN WOCHENSCHR. 2016; 128(19-20):761-761. [Oral Communication]
Web of Science

 

** Kovacs, G; Avian, A; Douschan, P; Foris, V; Olschewski, A; Olschewski, H Patients With Pulmonary Arterial Hypertension Less Represented In Clinical Trials - Who Are They And How Are They?
AM J RESP CRIT CARE. 2016; 193: -International Conference of the American-Thoracic-Society (ATS); MAY 13-18, 2016; San Francisco, CA. [Poster]
Web of Science

 

** Nagy, BM; Nagaraj, C; Egemnazarov, B; Kwapiszewska, G; Stauber, R; Avian, A; Olschewski, A; Olschewski, H Lack Of Abcg2 Leads To Biventricular Dysfunction And Remodelling In Response To Hypoxia
AM J RESP CRIT CARE. 2016; 193: -International Conference of the American-Thoracic-Society (ATS); MAY 13-18, 2016; San Francisco, CA. [Poster]
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** Nagy, BM; Nagaraj, C; Mangge, H; Meinitzer, A; Leithner, K; Kwapiszewska, G; Kovacs, G; Foris, V; Olschewski, A; Olschewski, H Kynurenine Causes Pulmonary Arterial Relaxation In Pulmonary Hypertension
AM J RESP CRIT CARE. 2016; 193: -International Conference of the American-Thoracic-Society (ATS); MAY 13-18, 2016; San Francisco, CA. [Poster]
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** Nagy, BM; Nagaraj, C; Olschewski, H; Olschewski, A The Role Of P22phox-Dependent Nadph Oxidases In Bleomycin-Induced Interstitial Lung Disease
AM J RESP CRIT CARE. .. 2016; 193: -International Conference of the American-Thoracic-Society (ATS); MAY 13-18, 2016; San Francisco, CA. [Poster]
Web of Science

 

** Odler, B; Douschan, P; Pfeiffer, S; Foris, V; Tornyos, A; Avian, A; Olschewski, A; Olschewski, H; Kovacs, G Diffusion capacity for nitric oxide: a novel marker for pulmonary hemodynamics and exercise capacity?
WIEN KLIN WOCHENSCHR. 2016; 128(19-20):768-768. [Poster]
Web of Science

 

** Pienn, M; Payer, C; Urschler, M; Salvan-Schaschl, C; Neuwirth, R; Stollberger, R; Kovacs, G; Foris, V; Olschewski, A; Olschewski, H; Balint, Z Reduced Venous Vessel Density In Pre-Capillary Pulmonary Hypertension
AM J RESP CRIT CARE. 2016; 193: -International Conference of the American-Thoracic-Society (ATS); MAY 13-18, 2016; San Francisco, CA. [Poster]
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** Tornyos, A; Trinker, M; Foris, V; Pfeiffer, S; Odler, B; Douschan, P; Avian, A; Olschewski, A; Kovacs, G; Olschewski, H Pulmonary hypertension in hypersensitivity pneumonitis
EUR RESPIR J. 2016; 48: -Annual Congress of European Respiratory Society; SEPT 3-7, 2016; London, UNITED KINGDOM. Doi: 10.1183/13993003.congress-PA2450 [Poster]
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Meeting Report

** Olschewski, A; Berghausen, EM; Eichstaedt, CA; Fleischmann, BK; Grünig, E; Grünig, G; Hansmann, G; Harbaum, L; Hennigs, JK; Jonigk, D; Kübler, WM; Kwapiszewska, G; Pullamsetti, SS; Stacher, E; Weissmann, N; Wenzel, D; Schermuly, RT [Pathobiology, pathology and genetics of pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016].
Dtsch Med Wochenschr. 2016; 141(S 01):S4-S9 Doi: 10.1055/s-0042-114520
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2015

Full paper/article (Journal)

** Egemnazarov, B; Schmidt, A; Crnkovic, S; Sydykov, A; Nagy, BM; Kovacs, G; Weissmann, N; Olschewski, H; Olschewski, A; Kwapiszewska, G; Marsh, LM Pressure Overload Creates Right Ventricular Diastolic Dysfunction in a Mouse Model: Assessment by Echocardiography.
J Am Soc Echocardiogr. 2015; 28(7):828-843 Doi: 10.1016/j.echo.2015.02.014
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** Fischer, C; Leithner, K; Wohlkoenig, C; Quehenberger, F; Bertsch, A; Olschewski, A; Olschewski, H; Hrzenjak, A Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization.
Mol Cancer. 2015; 14(8):4-4 Doi: 10.1186/1476-4598-14-4 [OPEN ACCESS]
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** Hoffmann, J; Marsh, LM; Pieper, M; Stacher, E; Ghanim, B; Kovacs, G; König, P; Wilkens, H; Haitchi, HM; Hoefler, G; Klepetko, W; Olschewski, H; Olschewski, A; Kwapiszewska, G Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients.
Am J Physiol Lung Cell Mol Physiol. 2015; 308(10): L1002-L1013. Doi: 10.1152/ajplung.00383.2014 [OPEN ACCESS]
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** Konya, V; Maric, J; Jandl, K; Luschnig, P; Aringer, I; Lanz, I; Platzer, W; Theiler, A; Bärnthaler, T; Frei, R; Marsche, G; Marsh, LM; Olschewski, A; Lippe, IT; Heinemann, A; Schuligoi, R Activation of EP₄ receptors prevents endotoxin-induced neutrophil infiltration into the airways and enhances microvascular barrier function.
Br J Pharmacol. 2015; 172(18):4454-4468 Doi: 10.1111/bph.13229 [OPEN ACCESS]
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** Leithner, K; Hrzenjak, A; Trötzmüller, M; Moustafa, T; Köfeler, HC; Wohlkoenig, C; Stacher, E; Lindenmann, J; Harris, AL; Olschewski, A; Olschewski, H PCK2 activation mediates an adaptive response to glucose depletion in lung cancer.
Oncogene. 2015; 34(8):1044-1050 Doi: 10.1038/onc.2014.47
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** Zabini, D; Crnkovic, S; Xu, H; Tscherner, M; Ghanim, B; Klepetko, W; Olschewski, A; Kwapiszewska, G; Marsh, LM High-mobility group box-1 induces vascular remodelling processes via c-Jun activation.
J Cell Mol Med. 2015; 19(5):1151-1161 Doi: 10.1111/jcmm.12519 [OPEN ACCESS]
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Review

** Olschewski, A; Weir, EK Redox regulation of ion channels in the pulmonary circulation.
Antioxid Redox Signal. 2015; 22(6):465-485 Doi: 10.1089/ars.2014.5899 [OPEN ACCESS]
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** Pugliese, SC; Poth, JM; Fini, MA; Olschewski, A; El Kasmi, KC; Stenmark, KR The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes.
Am J Physiol Lung Cell Mol Physiol. 2015; 308(3):L229-L252 Doi: 10.1152/ajplung.00238.2014 [OPEN ACCESS]
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Abstract (Journal)

** Biasin, V; Wygrecka, M; Gungl, A; Ghanim, B; Klepetko, W; Marsh, LM; Olschewski, A; Kwapiszewska, G Involvement of the proteases meprins in human lung fibrosis
WIEN KLIN WOCHENSCHR. 2015; 127(19-20):817-818. [Oral Communication]
Web of Science

 

** Chandran, N; Tang, B; Jain, P; Olschewski, A Specific activation of KCa channels contribute to Omega 3 fatty acid - Induced Pulmonary Vasodilation
FASEB J. 2015; 29: -Experimental Biology Meeting; MAR 28-APR 01, 2015; Boston, MA. [Oral Communication]
Web of Science

 

** Crnkovic, S; Jain, P; Egemnazarov, B; Marsh, LM; Ghanim, B; Klepetko, W; Holzer, P; Olschewski, A; Kwapiszewska, G Increased expression of NPY1R mediates increased vascular reactivity to NPY
WIEN KLIN WOCHENSCHR. 2015; 127(19-20):818-818. [Oral Communication]
Web of Science

 

** Douschan, P; Kovacs, G; Foris, V; Avian, A; Olschewski, A; Olschewski, H Survival and cardiopulmonary comorbidities in patients with high-normal- and borderline-PAP elevation
WIEN KLIN WOCHENSCHR. 2015; 127(19-20):824-824. [Poster]
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** Egemnazarov, B; Crnkovic, S; Olschewski, H; Olschewski, A; Marsh, L; Kwapiszewska, G The Role Of Cartilage Oligomeric Matrix Protein In Right Ventricular Fibrosis In The Pressure Overload Model Of Right Ventricular Dysfunction In Mice
AM J RESP CRIT CARE. 2015; 191: -International Conference of the American-Thoracic-Society (ATS); MAY 15-20, 2015; Denver, CO. [Poster]
Web of Science

 

** Egemnazarov, B; Crnkovic, S; Olschewski, H; Olschewski, A; Marsh, LM; Kwapiszewska, G Cartilage oligomeric matrix protein (COMP) as an adaptive mechanisms to the pressure overload in the right ventricle
WIEN KLIN WOCHENSCHR. 2015; 127(19-20):819-819. [Oral Communication]
Web of Science

 

** Fischer, C; Leithner, K; Wohlkoenig, C; Quehenberger, F; Bertsch, A; Olschewski, A; Olschewski, H; Hrzenjak, A Histone deacetylase inhibitor panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma via HIF-1α destabilisation
Wiener Klinische Wochenschrift. 2015; 127: 816-817.-Annual Meeting of the Austrian Society of Pneumology; Oct 15-17, 2015; Graz, Austria. [Poster]
Web of Science

 

** Foris, V; Kovacs, G; Douschan, P; Kqiku, X; Hesse, C; Avian, A; Bachmaier, G; Olschewski, A; Olschewski, H Acute Hemodynamic Response Of Pulmonary Hypertension Patients During Right Heart Catheterization
AM J RESP CRIT CARE. 2015; 191: -International Conference of the American-Thoracic-Society (ATS); MAY 15-20, 2015; Denver, CO. [Poster]
Web of Science

 

** Leithner, K; Hrzenjak, A; Trötzmüller, M; Köfeler, HC; Harris, AL; Olschewski, A; Olschewski, H Beyond Wrburg effect: Adaptation to low glucose involves use of glutamine as alternative carbon source in lung cancer cells
Wiener Klinische Wochenschrift. 2015; 127: 816-816.-Annual Meeting of the Austrian Society of Pneumology; Oct 15-17, 2015; Graz, Austria. [Poster]
Web of Science

 

** Marsh, L; Hoffmann, J; Ghanim, B; Klepetko, W; Olschewski, H; Olschewski, A; Kwapiszewska, G Diverse Forms Of Pulmonary Hypertension Possess Distinct Inflammatory Cell Profiles
AM J RESP CRIT CARE. 2015; 191: -International Conference of the American-Thoracic-Society (ATS); MAY 15-20, 2015; Denver, CO. [Oral Communication]
Web of Science

 

** Marsh, LM; Stacher, E; Hoffmann, J; Ghanim, B; Klepetko, W; Olschewski, H; Olschewski, A; Kwapiszewska, G Inflammatory profiling of chronic lung disease with associated pulmonary hypertension
WIEN KLIN WOCHENSCHR. 2015; 127(19-20):820-820. [Oral Communication]
Web of Science

 

** Nagaraj, C; Tang, B; Nagy, B; Papp, R; Jain, P; Marsh, L; Meredith, A; Klepetko, W; Ghanim, B; Olschewski, A DHA facilitates rapid pulmonary arterial relaxation via KCa channel mediated hyperpolarization in pulmonary hypertension
WIEN KLIN WOCHENSCHR. 2015; 127(19-20):820-820. [Oral Communication]
Web of Science

 

** Payer, C; Pienn, M; Urschler, M; Kovacs, G; Douschan, P; Olschewski, A; Olschewski, H; Balint, Z Regional differences in lung vessel morphology from thoracic CT images
WIEN KLIN WOCHENSCHR. 2015; 127(19-20):812-812. [Oral Communication]
Web of Science

 

** Pienn, M; Bredies, K; Stollberger, R; Kovacs, G; Olschewski, A; Olschewski, H; Balint, Z Denoising algorithm for quantitative assessment of thoracic dual-energy computed tomography images
WIEN KLIN WOCHENSCHR. 2015; 127(19-20):815-815. [Poster]
Web of Science

 

** Pienn, M; Payer, C; Kovacs, G; Foris, V; Urschler, M; Olschewski, A; Olschewski, H; Balint, Z Pulmonary arterial tortuosity as a non-invasive diagnostic tool for pulmonary arterial hypertension
WIEN KLIN WOCHENSCHR. 2015; 127(19-20):822-822. [Poster]
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Abstract (Proceedings)

** Douschan, P; Kovacs, G; Foris, V; Olschewski, A; Olschewski, H; FREQUENCY OF CARDIOPULMONARY COMORBIDITIES IN PATIENTS WITH PULMONARY HYPERTENSION
American Journal of Respiratory and Critical Care Medicine. 2015; 191: -ATS 2015; 15 - 20.05.2015; Denver, USA. [Poster]
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2014

Full paper/article (Journal)

** Bálint, Z; Zabini, D; Konya, V; Nagaraj, C; Végh, AG; Váró, G; Wilhelm, I; Fazakas, C; Krizbai, IA; Heinemann, A; Olschewski, H; Olschewski, A Double-stranded RNA attenuates the barrier function of human pulmonary artery endothelial cells.
PLoS One. 2014; 8(6):e63776-e63776 Doi: 10.1371/journal.pone.0063776 [OPEN ACCESS]
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** Biasin, V; Chwalek, K; Wilhelm, J; Best, J; Marsh, LM; Ghanim, B; Klepetko, W; Fink, L; Schermuly, RT; Weissmann, N; Olschewski, A; Kwapiszewska, G Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.
Int J Biochem Cell Biol. 2014; 54(3):137-148 Doi: 10.1016/j.biocel.2014.06.020
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** Biasin, V; Marsh, LM; Egemnazarov, B; Wilhelm, J; Ghanim, B; Klepetko, W; Wygrecka, M; Olschewski, H; Eferl, R; Olschewski, A; Kwapiszewska, G Meprin β, a novel mediator of vascular remodelling underlying pulmonary hypertension.
J Pathol. 2014; 233(1):7-17 Doi: 10.1002/path.4303
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** Crnkovic, S; Egemnazarov, B; Jain, P; Seay, U; Gattinger, N; Marsh, LM; Bálint, Z; Kovacs, G; Ghanim, B; Klepetko, W; Schermuly, RT; Weissmann, N; Olschewski, A; Kwapiszewska, G NPY/Y₁ receptor-mediated vasoconstrictory and proliferative effects in pulmonary hypertension.
Br J Pharmacol. 2014; 171(16):3895-3907 Doi: 10.1111/bph.12751 [OPEN ACCESS]
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** Helmberger, M; Pienn, M; Urschler, M; Kullnig, P; Stollberger, R; Kovacs, G; Olschewski, A; Olschewski, H; Bálint, Z Quantification of tortuosity and fractal dimension of the lung vessels in pulmonary hypertension patients.
PLoS One. 2014; 9(1):e87515-e87515 Doi: 10.1371/journal.pone.0087515 [OPEN ACCESS]
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** Hoffmann, J; Wilhelm, J; Marsh, LM; Ghanim, B; Klepetko, W; Kovacs, G; Olschewski, H; Olschewski, A; Kwapiszewska, G Distinct differences in gene expression patterns in pulmonary arteries of patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis with pulmonary hypertension.
Am J Respir Crit Care Med. 2014; 190(1):98-111 Doi: 10.1164/rccm.201401-0037OC
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** Jain, PP; Leber, R; Nagaraj, C; Leitinger, G; Lehofer, B; Olschewski, H; Olschewski, A; Prassl, R; Marsh, LM Liposomal nanoparticles encapsulating iloprost exhibit enhanced vasodilation in pulmonary arteries.
Int J Nanomedicine. 2014; 9(3):3249-3261 Doi: 10.2147/IJN.S63190 [OPEN ACCESS]
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** Kovacs, G; Avian, A; Tscherner, M; Foris, V; Bachmaier, G; Olschewski, A; Olschewski, H Characterization of patients with borderline pulmonary arterial pressure.
Chest. 2014; 146(6):1486-1493 Doi: 10.1378/chest.14-0194
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** Lehofer, B; Bloder, F; Jain, PP; Marsh, LM; Leitinger, G; Olschewski, H; Leber, R; Olschewski, A; Prassl, R Impact of atomization technique on the stability and transport efficiency of nebulized liposomes harboring different surface characteristics.
Eur J Pharm Biopharm. 2014; 88(3):1076-1085 Doi: 10.1016/j.ejpb.2014.10.009
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** Leithner, K; Wohlkoenig, C; Stacher, E; Lindenmann, J; Hofmann, NA; Gallé, B; Guelly, C; Quehenberger, F; Stiegler, P; Smolle-Jüttner, FM; Philipsen, S; Popper, HH; Hrzenjak, A; Olschewski, A; Olschewski, H Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model - role of tumor stroma cells.
BMC Cancer. 2014; 14(1):40-40 Doi: 10.1186/1471-2407-14-40 [OPEN ACCESS]
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** Peters, DM; Vadász, I; Wujak, L; Wygrecka, M; Olschewski, A; Becker, C; Herold, S; Papp, R; Mayer, K; Rummel, S; Brandes, RP; Günther, A; Waldegger, S; Eickelberg, O; Seeger, W; Morty, RE TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury.
Proc Natl Acad Sci U S A. 2014; 111(3):E374-E383 Doi: 10.1073/pnas.1306798111 [OPEN ACCESS]
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** Pienn, M; Kovacs, G; Tscherner, M; Avian, A; Johnson, TR; Kullnig, P; Stollberger, R; Olschewski, A; Olschewski, H; Bálint, Z Non-invasive determination of pulmonary hypertension with dynamic contrast-enhanced computed tomography: a pilot study.
Eur Radiol. 2014; 24(3):668-676 Doi: 10.1007/s00330-013-3067-8
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** Wolff, M; Schnöbel-Ehehalt, R; Mühling, J; Weigand, MA; Olschewski, A Mechanisms of lidocaine's action on subtypes of spinal dorsal horn neurons subject to the diverse roles of Na(+) and K(+) channels in action potential generation.
Anesth Analg. 2014; 119(2):463-470 Doi: 10.1213/ANE.0000000000000280
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** Zabini, D; Heinemann, A; Foris, V; Nagaraj, C; Nierlich, P; Bálint, Z; Kwapiszewska, G; Lang, IM; Klepetko, W; Olschewski, H; Olschewski, A Comprehensive analysis of inflammatory markers in chronic thromboembolic pulmonary hypertension patients.
Eur Respir J. 2014; 44(4):951-962 Doi: 10.1183/09031936.00145013 [OPEN ACCESS]
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Review

** Kwapiszewska, G; Viales, RR; Ehlken, N; Eichstaedt, CA; Riemekasten, G; Grünig, G; Mäder, I; Schröder, T; Klose, H; Hinderhofer, K; Fischer, C; Ulrich, S; Grünig, E; Olschewski, A Epigenetics and genetics of pulmonary arterial hypertension--new insights from the last years].
Dtsch Med Wochenschr. 2014; 139 Suppl 4: S111-S115. Doi: 10.1055/s-0034-1387454
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** Olschewski, A; Papp, R; Nagaraj, C; Olschewski, H Ion channels and transporters as therapeutic targets in the pulmonary circulation.
Pharmacol Ther. 2014; 144(3):349-368 Doi: 10.1016/j.pharmthera.2014.08.001
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** Riemekasten, G; Kuebler, WM; Schermuly, R; Seyfarth, HJ; Behr, J; Grohe, C; Hoeper, MM; Olschewski, A; Kwapiszewska, G; Ulrich, S; Voswinckel, R; Weissmann, N; Worth, H; Viales, RR; Pullamsetti, SS; Grunig, G Pulmonary arterial hypertension--a disease of the immune system?].
Dtsch Med Wochenschr. 2014; 139 Suppl 4:S116-S120 Doi: 10.1055/s-0034-1387452
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Abstract (Journal)

** Crnkovic, S; Marsh, LM; Jain, P; Metzger, D; Chambon, P; Offermanns, S; Voswinckel, R; Olschewski, A; Kwapiszewska, G Lineage tracing of neomuscularized vessels in hypoxia-induced pulmonary hypertension murine model
ANGIOGENESIS. 2014; 17(1):320-320. [Oral Communication]
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** Douschan, P; Kovacs, G; Foris, V; Olschewski, A; Olschewski, H PAH with comorbidities or secondary PH?-A retrospective analysis
WIEN KLIN WOCHENSCHR. 2014; 126(19-20):678-678.-ÖGO Jahrestagung; Salzburg, Austria. [Poster]
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** Douschan, P; Kovacs, G; Foris, V; Stauber, R; Olschewski, A; Olschewski, H Performance on cardiopulmonary exercise testing in patients with compensated liver cirrhosis
WIEN KLIN WOCHENSCHR. 2014; 126(19-20):684-684.-ÖGP Jahrestagung; Salzburg, Austria. [Poster]
Web of Science

 

** Egemnazarov, B; Schmidt, A; Crnkovic, S; Nagy, BM; Sydykov, A; Kovacs, G; Olschewski, H; Olschewski, A; Kwapiszewska, G; Marsh, LM; Pressure overload creates right ventricular diastolic dysfunction in a mouse model: assessment by echocardiography.
EUR J HEART FAIL. 2014; 16: 198-199.-???; ???; ???. [Poster]
Web of Science

 

** Foris, V; Kovacs, G; Marsh, L; Balint, Z; Totsch, M; Avian, A; Douschan, P; Tscherner, M; Olschewski, A; Olschewski, H Characterization of circulating CD133+progenitor cells in pulmonary arterial hypertension
EUR RESPIR J. 2014; 44: -European Respiratory Society Congress; SEPT. 6-10, 2014; München, Deutschland. [Poster]
Web of Science

 

** Foris, V; Kovacs, G; Marsh, L; Balint, Z; Totsch, M; Bachmaier, G; Ghanim, B; Klepetko, W; Olschewski, A; Olschewski, H CD133 positive progenitor cells are potential biomarkers for pulmonary arterial hypertension
WIEN KLIN WOCHENSCHR. 2014; 126(19-20):677-677.-Jahrestagung 2014 der Österreichischen Gesellschaft für Pneumologie; OCT 2-4, 2014; Salzburg, AUSTRIA. [Oral Communication]
Web of Science

 

** Hoffmann, J; Wilhelm, J; Marsh, LM; Ghanim, B; Klepetko, W; Kovacs, G; Olschewski, H; Olschewski, A; Kwapiszewska, G Differential gene expression pattern in pulmonary artery profiles of COPD and IPF patients with pulmonary hypertension
WIEN KLIN WOCHENSCHR. 2014; 126(19-20):677-678.-Austrian Society of Pneumology; Oct 2-4 2014; Salzburg. [Oral Communication]
Web of Science

 

** Hrzenjak, A; Fischer, C; Leithner, K; Wohlkoenig, C; Quehenberger, F; Olschewski, A; Olschewski, H Panobinostat reduces hypoxia-related cisplatin resistance of non-small cell lung carcinoma cells via HIF-1alpha destabilization.
EUR J CANCER. 2014; 50: S203-S204. Doi: 10.1016/S0959-8049(14)50741-1 [Poster]
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** Leithner, K; Hrzenjak, A; Trotzmuller, M; Moustafa, T; Kofeler, HC; Wohlkoenig, C; Stacher, E; Harris, AL; Olschewski, A; Olschewski, H; Role of the gluconeogenic enzyme phosphoenolpyruvate carboxykinase in lung cancer.
EUR J CANCER. 2014; 50: S84-S84.-EACR 23; Doi: 10.1016/S0959-8049(14)50315-2 [Poster]
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** Wurm, M; Pienn, M; Kovacs, G; Kullnig, P; Olschewski, A; Olschewski, H; Bálint, Z Lung volume histogram parameters correlate with lung function in patients with pulmonary hypertension
Jahrestagung 2014 der Österreichischen Gesellschaft für Pneumologie. 2014; 126: 678-679.-Jahrestagung 2014 der Österreichischen Gesellschaft für Pneumologie; OCT 2-4, 2014; Salzburg, AUSTRIA. [Oral Communication]
Web of Science FullText

 

2013

Full paper/article (Journal)

** Kovacs, G; Avian, A; Olschewski, A; Olschewski, H Zero reference level for right heart catheterisation.
Eur Respir J. 2013; 42(6):1586-1594 Doi: 10.1183/09031936.00050713 [OPEN ACCESS]
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** Nagaraj, C; Tang, B; Balint, Z; Wygrecka, M; Hrzenjak, A; Kwapiszewska, G; Stacher, E; Lindenmann, J; Weir, EK; Olschewski, H; Olschewski, A Src tyrosine kinase is crucial for potassium channel function in human pulmonary arteries.
Eur Respir J. 2013; 41(1):85-95 Doi: 10.1183/09031936.00211811 [OPEN ACCESS]
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** Pienn, M; Kovacs, G; Tscherner, M; Johnson, TR; Kullnig, P; Stollberger, R; Olschewski, A; Olschewski, H; Bálint, Z Determination of cardiac output with dynamic contrast-enhanced computed tomography.
Int J Cardiovasc Imaging. 2013; 29(8):1871-1878 Doi: 10.1007/s10554-013-0279-6
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** Stulnig, G; Frisch, MT; Crnkovic, S; Stiegler, P; Sereinigg, M; Stacher, E; Olschewski, H; Olschewski, A; Frank, S Docosahexaenoic acid (DHA)-induced heme oxygenase-1 attenuates cytotoxic effects of DHA in vascular smooth muscle cells.
Atherosclerosis. 2013; 230(2):406-413 Doi: 10.1016/j.atherosclerosis.2013.08.002
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Review

** Foris, V; Kovacs, G; Tscherner, M; Olschewski, A; Olschewski, H Biomarkers in pulmonary hypertension: what do we know?
Chest. 2013; 144(1):274-283 Doi: 10.1378/chest.12-1246
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Abstract (Journal)

** Bálint, Z; Helmberger, M; Pienn, M; Kovacs, G; Tscherner, M; Urschler, M; Olschewski, A; Olschewski, H; Quantitative determination of lung vessel tortuosity, but not fractal dimension correlates with lung function parameters of PH patients.
WIEN KLIN WOCHENSCHR. 2013; 125(19-20):647-647.-Jahrestagung der Österreichischen Gesellschaft für Pneumologie; OKT 24-26, 2013; Vienna, AUSTRIA. [Poster]
Web of Science

 

** Chandran, N; Tabeling, C; Marsh, L; Balint, Z; Witzenrath, M; Olschewski, H; Olschewski, A; Impact of the p22phox dependent NADPH-oxidase on hypoxia-induced pulmonary vasoconstriction and hypertension.
WIEN KLIN WOCHENSCHR. 2013; 125(19-20):648-649.-Jahrestagung der Österreichischen Gesellschaft für Pneumologie; OKT 24-26, 2013; Vienna, AUSTRIA. [Oral Communication]
Web of Science

 

** Crnkovic, S; Schmidt, A; Egemnazarov, B; Marsh, L; Olschewski, H; Olschewski, A; Olschewski, G; Kwapiszewska, G; Right ventricular hypertrophy in hypoxia-exposed mice is fully compensated and has a distinct molecular expression profile.
WIEN KLIN WOCHENSCHR. 2013; 125(19-20):649-649. [Poster]
Web of Science

 

** Foris, V; Kovacs, G; Tscherner, M; Avian, A; Olschewski, A; Olschewski, H; Apelin isoforms and GDF-15 are promising biomarkers for pulmonary hypertension.
WIEN KLIN WOCHENSCHR. 2013; 125(19-20):650-650.-Jahrestagung der Österreichischen Gesellschaft für Pulmonologie; Oktober 24-26, 2013; Vienna, Austria. [Oral Communication]
Web of Science

 

** Nagy, B; Nagaraj, C; Kwapiszewska, G; Olschewski, A; Olschewski, H Right Ventricular Diastolic Dysfunction in ABCG2 knockout mice under Hypoxia
CIRCULATION. 2013; 128(22): [Poster]
Web of Science

 

** Nagy, B; Nagaraj, C; Kwapiszewska, G; Olschewski, A; Olschewski, H; Accelerated right ventricular diastolic dysfunction in the ABCG2 knockout mouse.
WIEN KLIN WOCHENSCHR. 2013; 125(19-20):656-656.-ÖGP Jahrestagung 2013; OKT 24-26, 2013; Vienna, AUSTRIA. [Poster]
Web of Science

 

** Wohlkonig, C; Leithner, K; Hrzenjak, A; Olschewski, A; Olschewski, H; Cytosporone B, an nr4a1 specific cytotoxic agent, is not prone to hypoxia-induced apoptosis resistance in A549 cells.
WIEN KLIN WOCHENSCHR. 2013; 125(19-20):663-663.-ÖGP; OKT 24-26, 2013; Vienna, AUSTRIA. [Poster]
Web of Science

 

** Zabini, D; Balint, Z; Nagarai, C; Foris, V; Kwapiszewska, G; Heinemann, A; Heinemann, I; Lang, W; Klepetko, H; Olschewski, H; Olschewski, A; Cytokines in chronic thromboembolic pulmonary hypertension.
WIEN KLIN WOCHENSCHR. 2013; 125(19-20):663-664.-Jahrestagung 2013 der Österreichischen Gesellschaft für Pneumologie; OKT 24-26, 2013; Vienna, AUSTRIA. [Poster]
Web of Science

 

Comment

** Olschewski, A; Nagaraj, C; Olschewski, H A novel channelopathy in pulmonary arterial hypertension.
N Engl J Med. 2013; 369(22):2161-2161 Doi: 10.1056/NEJMc1311060#SA1 [OPEN ACCESS]
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2012

Full paper/article (Journal)

** Crnkovic, S; Riederer, M; Lechleitner, M; Hallström, S; Malli, R; Graier, WF; Lindenmann, J; Popper, H; Olschewski, H; Olschewski, A; Frank, S Docosahexaenoic acid-induced unfolded protein response, cell cycle arrest, and apoptosis in vascular smooth muscle cells are triggered by Ca²⁺-dependent induction of oxidative stress.
Free Radic Biol Med. 2012; 52(9):1786-1795 Doi: 10.1016/j.freeradbiomed.2012.02.036 [OPEN ACCESS]
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** Fiorillo, C; Moro, F; Brisca, G; Astrea, G; Nesti, C; Balint, Z; Olschewski, A; Meschini, MC; Guelly, C; Auer-Grumbach, M; Battini, R; Pedemonte, M; Romano, A; Menchise, V; Biancheri, R; Santorelli, FM; Bruno, C TRPV4 mutations in children with congenital distal spinal muscular atrophy.
Neurogenetics. 2012; 13(3):195-203 Doi: 10.1007/s10048-012-0328-7 (- Case Report)
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** Kovacs, G; Olschewski, A; Berghold, A; Olschewski, H Pulmonary vascular resistances during exercise in normal subjects: a systematic review.
Eur Respir J. 2012; 39(2):319-328 Doi: 10.1183/09031936.00008611 [OPEN ACCESS]
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** Kwapiszewska, G; Chwalek, K; Marsh, LM; Wygrecka, M; Wilhelm, J; Best, J; Egemnazarov, B; Weisel, FC; Osswald, SL; Schermuly, RT; Olschewski, A; Seeger, W; Weissmann, N; Eickelberg, O; Fink, L BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension.
Am J Pathol. 2012; 181(6):2018-2029 Doi: 10.1016/j.ajpath.2012.08.028 [OPEN ACCESS]
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** Kwapiszewska, G; Markart, P; Dahal, BK; Kojonazarov, B; Marsh, LM; Schermuly, RT; Taube, C; Meinhardt, A; Ghofrani, HA; Steinhoff, M; Seeger, W; Preissner, KT; Olschewski, A; Weissmann, N; Wygrecka, M PAR-2 inhibition reverses experimental pulmonary hypertension.
Circ Res. 2012; 110(9):1179-1191 Doi: 10.1161/CIRCRESAHA.111.257568 [OPEN ACCESS]
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** Li, Y; Connolly, M; Nagaraj, C; Tang, B; Bálint, Z; Popper, H; Smolle-Juettner, FM; Lindenmann, J; Kwapiszewska, G; Aaronson, PI; Wohlkoenig, C; Leithner, K; Olschewski, H; Olschewski, A Peroxisome proliferator-activated receptor-β/δ, the acute signaling factor in prostacyclin-induced pulmonary vasodilation.
Am J Respir Cell Mol Biol. 2012; 46(3):372-379 Doi: 10.1165/rcmb.2010-0428OC
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** Zabini, D; Nagaraj, C; Stacher, E; Lang, IM; Nierlich, P; Klepetko, W; Heinemann, A; Olschewski, H; Bálint, Z; Olschewski, A Angiostatic factors in the pulmonary endarterectomy material from chronic thromboembolic pulmonary hypertension patients cause endothelial dysfunction.
PLoS One. 2012; 7(8):e43793-e43793 Doi: 10.1371/journal.pone.0043793 [OPEN ACCESS]
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Abstract (Journal)

** Foris, V; Kovacs, G; Marsh, L; Tscherner, M; Olschewski, A; Olschewski, H; Phenotypical characterization of circulating endothelial progenitor cells in pulmonary hypertension.
WIEN KLIN WOCHENSCHR. 2012; 124(13-14):482-482.-ÖGP Jahrestagung; JUN 13-15, 2012; Salzburg. [Poster]
Web of Science

 

** Kovacs, G; Foris, V; Tscherner, M; Avian, A; Kqiku, X; Olschewski, A; Olschewski, H Routine non-invasive parameters in the practical diagnostic work-up of patients with risk for pulmonary hypertension.
WIEN KLIN WOCHENSCHR. 2012; 124(13-14):486-486.-Jahrestagung 2012 der Österreichischen Gesellschaft für Pneumologie; JUN 14-16, 2012; Salzburg, AUSTRIA. [Poster]
Web of Science

 

** Tscherner, M; Kovacs, G; Foris, V; Avian, A; Olschewski, A; Olschewski, H The measurement of end-tidal CO2 may help to differentiate between PH due to chronic lung or heart disease and CTEPH.
WIEN KLIN WOCHENSCHR. 2012; 124(13-14):490-490.-Jahrestagung 2012 der Österreichischen Gesellschaft für Pneumologie; JUN 14-16, 2012; Salzburg, AUSTRIA. [Poster]
Web of Science

 

2011

Full paper/article (Journal)

** Crnkovic, S; Hrzenjak, A; Marsh, LM; Olschewski, A; Kwapiszewska, G Origin of neomuscularized vessels in mice exposed to chronic hypoxia.
Respir Physiol Neurobiol. 2011; 179(2-3):342-345 Doi: 10.1016/j.resp.2011.09.016
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** Konya, V; Philipose, S; Bálint, Z; Olschewski, A; Marsche, G; Sturm, EM; Schicho, R; Peskar, BA; Schuligoi, R; Heinemann, A Interaction of eosinophils with endothelial cells is modulated by prostaglandin EP4 receptors.
Eur J Immunol. 2011; 41(8):2379-2389 Doi: 10.1002/eji.201141460 [OPEN ACCESS]
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** Wohlkoenig, C; Leithner, K; Deutsch, A; Hrzenjak, A; Olschewski, A; Olschewski, H Hypoxia-induced cisplatin resistance is reversible and growth rate independent in lung cancer cells.
Cancer Lett. 2011; 308(2): 134-143. Doi: 10.1016/j.canlet.2011.03.014
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Abstract (Journal)

** Balint, Z; Zabini, D; Klepetko, W; Lang, I; Olschewski, H; Olschewski, A Endothelial cells involved in chronic thromboembolic pulmonary hypertension have altered calcium homeostasis
EUR BIOPHYS J BIOPHY. 2011; 40: 187-187. [Poster]
Web of Science

 

** Fiorillo, C; Moro, F; Astrea, G; Battini, R; Gully, C; Olschewski, A; Auer-Grumbach, M; Bruno, C; Santorelli, FM Novel mutation of TRPV4 in congenital distal SMA with vocal cord paralysis
NEUROMUSCULAR DISORD. 2011; 21(9-10):682-682.-16th International Congress of the World-Muscle-Society; OCT 18-22, 2011; Algarve, PORTUGAL. Doi: 10.1016/j.nmd.2011.06.896 [Poster]
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** Kovacs, G; Olschewski, A; Berghold, A; Olschewski, H Resting and exercise pulmonary vascular resistances in healthy individuals
WIEN KLIN WOCHENSCHR. 2011; 123(17-18):A22-A22.-Jahrestagung 2011 der Österreichischen Gesellschaft für Pneumologie; SEP 8-10, 2011; Vienna, AUSTRIA. [Poster]
Web of Science

 

** Leithner, K; Wohlkoenig, C; Stacher, E; Lindenmann, J; Ebner, B; Guelly, C; Smolle-Jüttner, FM; Popper, HH; Hrzenjak, A; Olschewski, A; Olschewski, H Neprilysin is induced by hypoxia and is a prognostic factor in non-small cell lung cancer
WIEN KLIN WOCHENSCHR. 2011; 123(17-18):A24-A24.-Jahrestagung der Österreichischen Gesellschaft für Pneumologie; SEPT 8-10, 2011; Vienna, AUSTRIA. [Oral Communication]
Web of Science

 

** Wohlkoenig, C; Leithner, K; Hrzenjak, A; Olschewski, A; Olschewski, H Down-regulation of the pro-apoptotic BCL-2 family member protein Bax by hypoxia may contribute to hypoxia-induced chemotherapy resistance in A549 lung cancer cells
WIEN KLIN WOCHENSCHR. 2011; 123(17-18):A33-A33.-Jahrestagung der Österreichischen Gesellschaft für Pneumologie; SEPT 8-10, 2011; Vienna, AUSTRIA. [Oral Communication]
Web of Science

 

** Zabini, D; Balint, Z; Heinemann, A; Nierlich, P; Lang, I; Olschewski, A High chemokine levels are present in PEA tissue of CTEPH patients
WIEN KLIN WOCHENSCHR. 2011; 123(17-18): A34-A34. [Poster]
Web of Science

 

** Zabini, D; Bálint, Z; Olschewski, H; Olschewski, A Effect of collagen type I on human pulmonary artery endothelial cells
EUR BIOPHYS J BIOPHY. 2011; 40: 166-166. [Poster]
Web of Science

 

Comment

** Olschewski, A Blocking potassium channels: a new principle for treating restenosis?
Cardiovasc Res. 2011; 89(2):255-257 Doi: 10.1093/cvr/cvq388 [OPEN ACCESS]
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2010

Full paper/article (Journal)

** Auer-Grumbach, M; Olschewski, A; Papić, L; Kremer, H; McEntagart, ME; Uhrig, S; Fischer, C; Fröhlich, E; Bálint, Z; Tang, B; Strohmaier, H; Lochmüller, H; Schlotter-Weigel, B; Senderek, J; Krebs, A; Dick, KJ; Petty, R; Longman, C; Anderson, NE; Padberg, GW; Schelhaas, HJ; van Ravenswaaij-Arts, CM; Pieber, TR; Crosby, AH; Guelly, C Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C.
Nat Genet. 2010; 42(2):160-164 Doi: 10.1038/ng.508 [OPEN ACCESS]
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Abstract (Journal)

** Crnkovic, S; Lindenmann, J; Popper, H; Olschewski, H; Olschewski, A; Frank, S DHA inhibits HPASMC proliferation by induction of ER stress
WIEN KLIN WOCHENSCHR. 2010; 122(21-22):A59-A59. [Oral Communication]
Web of Science

 

** Frille, A; Wohlkoenig, C; Leithner, K; Hrzenjak, A; Olschewski, A; Olschewski, H. The influence of erythropoietin on proliferation in lung cancer cell lines
Wiener Klinische Wochenschrift2010; 122(21-2):A51--Jahrestagung 2010 der Österreichischen Gesellschaft für Pneumologie; OKT 7-9, 2010; Graz, AUSTRIA. [Poster]
Web of Science

 

** Leithner, K; Wohlkoenig, C; Li, Y; Tang, B; Nagaraj, C; Stacher, E; Balint, Z; Olschewski, A; Olschewski, H Expression of TASK-1 and TASK-3 channels in non-small cell lung cancer
EJC SUPPL. 2010; 8(5): 576 Doi: 10.1016/S1359-6349(10)71377-X [Poster]
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** Leithner, K; Wohlkoenig, C; Stacher, E; Lindenmann, J; Smolle-Juttner, F; Popper, HH; Hrzenjak, A; Olschewski, A; Olschewski, H Constitutive expression of carbonic anhydrase IX in hypoxic and normoxic non-small cell lung cancer fragments
EJC SUPPL. 2010; 8(5): 192 Doi: 10.1016/S1359-6349(10)70999-X [Poster]
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** Leithner, K; Wohlkoenig, C; Stacher, E; Lindenmann, J; Smolle-Juttner, FM; Popper, HH; Hrzenjak, A; Olschewski, A; Olschewski, H Expression of key enzymes for gluconeogenesis and glycogen deposition in lung cancer
WIEN KLIN WOCHENSCHR. 2010; 122(21-22): A50-A50. [Poster]
Web of Science

 

** Wohlkoenig, C; Leithner, K; Hrzenjak, A; Olschewski, A; Olschewski, H Blocking autocrine secreted vascular endothelial growth factor does not enhance cisplatin-induced apoptosis in non-small cell lung cancer cell lines
Wiener Klinische Wochenschrift 2010; 122(21-2):A53--Jahrestagung 2010 der Österreichischen Gesellschaft für Pneumologie; OKT 7-9, 2010; Graz. [Oral Communication]
Web of Science

 

** Wohlkoenig, C; Leithner, K; Hrzenjak, A; Olschewski, A; Olschewski, H Autocrine vascular endothelial growth factor signaling has no influence on the apoptosis induction by cisplatin in non-small cell lung cancer cell lines
EJC SUPPL. 2010; 8(5): 538 Doi: 10.1016/S1359-6349(10)71339-2 [Poster]
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** Zabini, D; Balint, Z; Klepetko, W; Lang, I; Olschewski, H; Olschewski, A Neovascularisation in clots of chronic thromboembolic pulmonary artery hypertension patients
WIEN KLIN WOCHENSCHR. 2010; 122(21-22): A52-A53. [Oral Communication]
Web of Science

 

Full paper/article (Proceedings)

** Olschewski, A Targeting TASK-1 Channels as a Therapeutic Approach
ADVAN EXPERIMENT MED BIOL. 2010; 661: 459-473. Doi: 10.1007/978-1-60761-500-2_30
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2009

Full paper/article (Journal)

** Leithner, K; Stacher, E; Wurm, R; Ploner, F; Quehenberger, F; Wohlkoenig, C; Bálint, Z; Polachova, J; Olschewski, A; Samonigg, H; Popper, HH; Olschewski, H Nuclear and cytoplasmic death receptor 5 as prognostic factors in patients with non-small cell lung cancer treated with chemotherapy.
Lung Cancer. 2009; 65(1):98-104 Doi: 10.1016/j.lungcan.2008.10.015
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** Olschewski, A; Schnoebel-Ehehalt, R; Li, Y; Tang, B; Bräu, ME; Wolff, M Mexiletine and lidocaine suppress the excitability of dorsal horn neurons.
Anesth Analg. 2009; 109(1): 258-264. Doi: 10.1213/ane.0b013e3181a3d5d8 [OPEN ACCESS]
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** Tang, B; Li, Y; Nagaraj, C; Morty, RE; Gabor, S; Stacher, E; Voswinckel, R; Weissmann, N; Leithner, K; Olschewski, H; Olschewski, A Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells.
Am J Respir Cell Mol Biol. 2009; 41(4): 476-483. Doi: 10.1165/rcmb.2008-0412OC
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Abstract (Journal)

** Bálint, Z; Zabini, D; Konya, V; Graier, WF; Preissner, KT; Heinemann, A; Olschewski, H; Olschewski, A Alteration of temporal calcium signalling in human pulmonary artery endothelial cells by double-stranded RNA
WIEN KLIN WOCHENSCHR. 2009; 121(17-18):A45-A46.-ÖGP; JUN 11-13, 2009; Salzburg, AUSTRIA. [Oral Communication]
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** Bálint, Z; Zabini, D; Végh, GA; Váró, G; Wilhelm, I; Krizbai, IA; Kónya, V; Heinemann, A; Olschewski, H; Olschewski, A Double-Stranded RNA Causes Leakage in Human Pulmonary Artery Endothelial Cell Monolayer
Circulation2009; 120(18):S1109--American Heart Association's Scientific Sessions 2009; NOV 14-18; Orlando, Florida, USA. [Poster]
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** Leithner, K; Wohlkoenig, C; Stacher, E; Lindenmann, J; Popper, HH; Hrzenjak, A; Olschewski, A; Olschewski, H Moderate hypoxia induces hypoxic adaptation in an ex-vivo non-small cell lung cancer model
Wiener Klinische Wochenschrift 2009; 121(17-1):A50--ÖGP Annual Congress; JUN 11-13; Salzburg, AUSTRIA. [Poster]
Web of Science

 

** Li, YJ; Connolly, M; Tang, B; Nagaraj, C; Bálint, Z; Smolle-Juttner, F; Popper, H; Aaronson, P; Olschewski, A Prostacyclin Analogues Activates Calcium-dependent Potassium (K-Ca) Channels via PPAR beta/delta in Pulmonary Artery
CIRCULATION. 2009; 120(18):S1021-S1022.-American Heart Association Scientific Session; NOV 14-18, 2009; Orlando, USA. [Poster]
Web of Science

 

** Nagaraj, C; Tang, B; Bálint, Z; Lindenmann, J; Stacher, E; Haenze, J; Olschewski, A Localization of NADPH Oxidase-4 is Crucial in Determining the Oxygen Sensitivity of TASK-1 Channel in Primary Human Pulmonary Artery Smooth Muscle Cells
Circulation2009; 120(18):S626--American Heart Association´s Scientific Session 2009; NOV 13-18, 2009; Orlando, Florida, USA. [Poster]
Web of Science

 

** Zabini, D; Bálint, Z; Graier, WF; Hrzenjak, A; Olschewski, H; Olschewski, A Double-stranded RNA affects the TRPC channel expression in human pulmonary artery endothelial cells
WIEN KLIN WOCHENSCHR. 2009; 121(17-18):A57-A58.-ÖGP; JUN 11-13, 2009; Salzburg, AUSTRIA. [Oral Communication]
Web of Science

 

2007

Full paper/article (Journal)

** Fontana, M; Olschewski, H; Olschewski, A; Schlüter, KD Treprostinil potentiates the positive inotropic effect of catecholamines in adult rat ventricular cardiomyocytes.
BRIT J PHARMACOL. 2007; 151(6): 779-786. Doi: 10.1038/sj.bjp.0707300 [OPEN ACCESS]
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** Wolff, M; Heugel, P; Hempelmann, G; Scholz, A; Mühling, J; Olschewski, A Clonidine reduces the excitability of spinal dorsal horn neurones.
Br J Anaesth. 2007; 98(3): 353-361. Doi: 10.1093/bja/ael379 [OPEN ACCESS]
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2006

Full paper/article (Journal)

** Hong, Z; Hong, F; Olschewski, A; Cabrera, JA; Varghese, A; Nelson, DP; Weir, EK Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus.
CIRCULATION. 2006; 114: 1372-1379. Doi: 10.1161/CIRCULATIONAHA.106.641126 [OPEN ACCESS]
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** Olschewski, A; Li, Y; Tang, B; Hanze, J; Eul, B; Bohle, RM; Wilhelm, J; Morty, RE; Brau, ME; Weir, EK; Kwapiszewska, G; Klepetko, W; Seeger, W; Olschewski, H Impact of TASK-1 in human pulmonary artery smooth muscle cells.
Circ Res. 2006; 98(8):1072-1080 Doi: 10.1161/01.RES.0000219677.12988.e9 [OPEN ACCESS]
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** Weissmann, N; Dietrich, A; Fuchs, B; Kalwa, H; Ay, M; Dumitrascu, R; Olschewski, A; Storch, U; Mederos y Schnitzler, M; Ghofrani, HA; Schermuly, RT; Pinkenburg, O; Seeger, W; Grimminger, F; Gudermann, T Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange.
Proc Natl Acad Sci U S A. 2006; 103(50):19093-19098 Doi: 10.1073/pnas.0606728103 [OPEN ACCESS]
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Review

** Weir, EK; Olschewski, A Role of ion channels in acute and chronic responses of the pulmonary vasculature to hypoxia.
CARDIOVASC RES. 2006; 71(4): 630-641. Doi: 10.1016/j.cardiores.2006.04.014 [OPEN ACCESS]
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Abstract (Journal)

** Li, Y; Tang, B; Hanze, J; Eul, B; Bohle, RM; Wilhelm, J; Morty, RE; Weir, EK; Klepetko, W; Olschewski, A; Olschewski, H The two-pore domain K+ channel TASK-1 largely contributes to resting membrane potential in human pulmonary artery smooth muscle cells
MED KLIN. ; 101: A83-A83.-DGIM; APR 22-26, 2006; Wiesbaden, Deutschland. [Poster]
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** Tang, B; Li, Y; Haenze, J; Eul, B; Morty, RE; Olschewski, A; Olschewski, H The two-pore domain K+ channel TASK-1 is blocked by endothelin-1 in human pulmonary artery smooth muscle cells
MED KLIN. ; 101: A83-A83.-DGIM; APR 22-26, 2006; Wiesbaden, Deutschland. [Poster]
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2005

Full paper/article (Journal)

** Hong, Z; Weir, EK; Varghese, A; Olschewski, A Effect of normoxia and hypoxia on K(+) current and resting membrane potential of fetal rabbit pulmonary artery smooth muscle.
Physiol Res. 2005; 54(2):175-184 Doi: 10.33549/physiolres.930461 [OPEN ACCESS]
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** Schnoebel, R; Wolff, M; Peters, SC; Brau, ME; Scholz, A; Hempelmann, G; Olschewski, H; Olschewski, A Ketamine impairs excitability in superficial dorsal horn neurones by blocking sodium and voltage-gated potassium currents
BRIT J PHARMACOL. 2005; 146(6): 826-833. Doi: 10.1038/sj.bjp.0706385 [OPEN ACCESS]
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** Vadász, I; Morty, RE; Kohstall, MG; Olschewski, A; Grimminger, F; Seeger, W; Ghofrani, HA Oleic acid inhibits alveolar fluid reabsorption: a role in acute respiratory distress syndrome?
AMER J RESPIR CRIT CARE MED 2005 171: 469-479. Doi: 10.1164/rccm.200407-954OC [OPEN ACCESS]
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** Vadász, I; Morty, RE; Olschewski, A; Königshoff, M; Kohstall, MG; Ghofrani, HA; Grimminger, F; Seeger, W Thrombin impairs alveolar fluid clearance by promoting endocytosis of Na+,K+-ATPase.
AMER J RESPIR CELL MOLEC BIOL 2005 33: 343-354. Doi: 10.1165/rcmb.2004-0407OC [OPEN ACCESS]
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Abstract (Journal)

** Morty, RE; Vadasz, I; Olschewski, A; Seeger, W; Eickelberg, O Transforming growth factor-beta blocks alveolar fluid reabsorption by inhibiting the epithelial sodium channel ENaC
FEBS J. 2005; 272: 195-195.
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2004

Full paper/article (Journal)

** Hong, Z; Olschewski, A; Reeve, HL; Nelson, DP; Hong, F; Weir, EK Nordexfenfluramine causes more severe pulmonary vasoconstriction than dexfenfluramine.
AMER J PHYSIOL-LUNG CELL M PH 2004 286: L531-L538. Doi: 10.1152/ajplung.00247.2003 [OPEN ACCESS]
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** Hong, Z; Weir, EK; Nelson, DP; Olschewski, A Subacute hypoxia decreases voltage-activated potassium channel expression and function in pulmonary artery myocytes.
AMER J RESPIR CELL MOLEC BIOL 2004 31: 337-343. Doi: 10.1165/rcmb.2003-0386OC [OPEN ACCESS]
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** Olschewski, A; Hong, Z; Peterson, DA; Nelson, DP; Porter, VA; Weir, EK Opposite effects of redox status on membrane potential, cytosolic calcium, and tone in pulmonary arteries and ductus arteriosus.
AMER J PHYSIOL-LUNG CELL M PH 2004 286: L15-L22. Doi: 10.1152/ajplung.00372.2002 [OPEN ACCESS]
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** Wolff, M; Olschewski, A; Vogel, W; Hempelmann, G Meperidine suppresses the excitability of spinal dorsal horn neurons.
ANESTHESIOLOGY 2004 100: 947-955. Doi: 10.1097/00000542-200404000-00027 [OPEN ACCESS]
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Review

** Olschewski, H; Rose, F; Schermuly, R; Ghofrani, HA; Enke, B; Olschewski, A; Seeger, W Prostacyclin and its analogues in the treatment of pulmonary hypertension.
Pharmacol Ther. 2004; 102(2):139-153 Doi: 10.1016/j.pharmthera.2004.01.003
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2003

Full paper/article (Journal)

** Bischoff, U; Bräu, ME; Vogel, W; Hempelmann, G; Olschewski, A Local anaesthetics block hyperpolarization-activated inward current in rat small dorsal root ganglion neurones.
BRIT J PHARMACOL 2003 139: 1273-1280. Doi: 10.1038/sj.bjp.0705363 [OPEN ACCESS]
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2002

Full paper/article (Journal)

** Olschewski, A; Hong, Z; Linden, BC; Porter, VA; Weir, EK; Cornfield, DN Contribution of the K(Ca) channel to membrane potential and O2 sensitivity is decreased in an ovine PPHN model.
AMER J PHYSIOL-LUNG CELL M PH 2002 283: L1103-L1109. Doi: 10.1152/ajplung.00100.2002 [OPEN ACCESS]
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** Olschewski, A; Hong, Z; Nelson, DP; Weir, EK Graded response of K+ current, membrane potential, and Ca2+i to hypoxia in pulmonary arterial smooth muscle.
AMER J PHYSIOL-LUNG CELL M PH 2002 283: L1143-L1150. Doi: 10.1152/ajplung.00104.2002 [OPEN ACCESS]
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** Olschewski, A; Wolff, M; Bräu, ME; Hempelmann, G; Vogel, W; Safronov, BV Enhancement of delayed-rectifier potassium conductance by low concentrations of local anaesthetics in spinal sensory neurones.
BRIT J PHARMACOL 2002 136: 540-549. Doi: 10.1038/sj.bjp.0704754 [OPEN ACCESS]
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Abstract (Journal)

** Olschewski, AJ; Olschewski, H; Hong, ZG; Weir, EK Iloprost activates lberiotoxin-sensitive potassium current, hyperpolarizes resting membrane potential and decreases cytosolic calcium in fetal and adult pulmonary artery smooth muscle cells
CIRCULATION 2002 106: 228-229.
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2001

Full paper/article (Journal)

** Bräu, ME; Dreimann, M; Olschewski, A; Vogel, W; Hempelmann, G Effect of drugs used for neuropathic pain management on tetrodotoxin-resistant Na(+) currents in rat sensory neurons.
ANESTHESIOLOGY 2001 94: 137-144. Doi: 10.1097/00000542-200101000-00024 [OPEN ACCESS]
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** Olschewski, A; Hempelmann, G; Vogel, W; Safronov, BV Suppression of potassium conductance by droperidol has influence on excitability of spinal sensory neurons.
ANESTHESIOLOGY 2001 94: 280-289. Doi: 10.1097/00000542-200102000-00018 [OPEN ACCESS]
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** Olschewski, A; Olschewski, H; Bräu, ME; Hempelmann, G; Vogel, W; Safronov, BV Basic electrical properties of in situ endothelial cells of small pulmonary arteries during postnatal development.
Am J Respir Cell Mol Biol. 2001; 25(3):285-290 Doi: 10.1165/ajrcmb.25.3.4373 [OPEN ACCESS]
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Review

** Olschewski, H; Olschewski, A; Rose, F; Schermuly, R; Schütte, H; Weissmann, N; Seeger, W; Grimminger, F Physiologic basis for the treatment of pulmonary hypertension.
J Lab Clin Med. 2001; 138(5):287-297 Doi: 10.1067/mlc.2001.119329
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Editorial

** Weissmann, N; Grimminger, F; Olschewski, A; Seeger, W Hypoxic pulmonary vasoconstriction: a multifactorial response?
AMER J PHYSIOL-LUNG CELL M PH 2001 281: L314-L317. Doi: 10.1152/ajplung.2001.281.2.L314 [OPEN ACCESS]
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Abstract (Journal)

** Hong, ZG; Olschewski, AJ; Weir, KE Effects of sub-acute hypoxia an expression of potassium channels in rat intrapulmonary arteries
CIRCULATION 2001 104: 402-402.
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** Olschewski, AJ; Weir, KE Graded response of potassium current and membrane potential to hypoxia in rat pulmonary arterial smooth muscle cells
CIRCULATION 2001 104: 605-605.
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** Olschewski, H; Brau, M; Wolff, M; Hempelmann, G; Vogel, W; Olschewski, A Small pulmonary artery endothelial cells are depolarized by factors associated with lung ischaemia
EUR HEART J 2001 22: 321-321.
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2000

Full paper/article (Journal)

** Bräu, ME; Branitzki, P; Olschewski, A; Vogel, W; Hempelmann, G Block of neuronal tetrodotoxin-resistant Na+ currents by stereoisomers of piperidine local anesthetics.
ANESTH ANALG 2000 91: 1499-1505. Doi: 10.1097/00000539-200012000-00038 [OPEN ACCESS]
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** Olschewski, A; Bräu, ME; Hempelmann, G; Vogel, W; Safronov, BV Differential block of fast and slow inactivating tetrodotoxin-sensitive sodium channels by droperidol in spinal dorsal horn neurons.
Anesthesiology. 2000; 92(6):1667-1676 Doi: 10.1097/00000542-200006000-00026 [OPEN ACCESS]
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1999

Full paper/article (Journal)

** Olschewski, A; Olschewski, H; Bräu, ME; Hempelmann, G; Vogel, W; Safronov, BV Effect of bupivacaine on ATP-dependent potassium channels in rat cardiomyocytes.
Br J Anaesth. 1999; 82(3):435-438 Doi: 10.1093/bja/82.3.435 [OPEN ACCESS]
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1998

Full paper/article (Journal)

** Olschewski, A; Hempelmann, G; Vogel, W; Safronov, BV Blockade of Na+ and K+ currents by local anesthetics in the dorsal horn neurons of the spinal cord.
ANESTHESIOLOGY 1998 88: 172-179. Doi: 10.1097/00000542-199801000-00025 [OPEN ACCESS]
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1996

Full paper/article (Journal)

** Olschewski, A; Bräu, ME; Olschewski, H; Hempelmann, G; Vogel, W ATP-dependent potassium channel in rat cardiomyocytes is blocked by lidocaine. Possible impact on the antiarrhythmic action of lidocaine.
Circulation. 1996; 93(4):656-659 Doi: 10.1161/01.CIR.93.4.656 [OPEN ACCESS]
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