Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Weiss Manfred |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2024
Originalarbeit (Zeitschrift)
** Tiffner, KI; Ramezanli, T; Boulgaropoulos, B; Birngruber, T; Bodenlenz, M; Lackner, BC; Raml, R; Jiang, Y; Raney, SG; Sinner, F
Cutaneous pharmacokinetics-based bioequivalence: A clinical dermal open flow microperfusion verification study using lidocaine and prilocaine combination topical products
EUR J PHARM SCI. 2024; 200: 106827
Doi: 10.1016/j.ejps.2024.106827
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2023
Abstract (Zeitschrift)
** Tiffner, K; Ehall, B; Eberl, A; Bodenlenz, M; Pircher, T; Birngruber, T; Sinner, F; Svehlikova, E; Pieber, T
Dermal open flow microperfusion (dOFM) to monitor local tissue response after dupilumab treatment in lesional and non-lesional skin of atopic dermatitis patients
J INVEST DERMATOL. 2023; 143(11):S348-S348.-5th Inflammatory Skin Disease Summit (ISDS); NOV 15-18, 2023; Vienna, AUSTRIA.
[Poster]
Web of Science
2020
Originalarbeit (Zeitschrift)
** Bodenlenz, M; Augustin, T; Birngruber, T; Tiffner, KI; Boulgaropoulos, B; Schwingenschuh, S; Raney, SG; Rantou, E; Sinner, F
Variability of Skin Pharmacokinetic Data: Insights from a Topical Bioequivalence Study Using Dermal Open Flow Microperfusion.
Pharm Res. 2020; 37(10):204-204
Doi: 10.1007/s11095-020-02920-x
[OPEN ACCESS]
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PubMed
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2019
Originalarbeit (Zeitschrift)
** Pipper, C; Bordag, N; Reiter, B; Economides, K; Florian, P; Birngruber, T; Sinner, F; Bodenlenz, M; Eberl, A
LC/MS/MS analyses of open-flow microperfusion samples quantify eicosanoids in a rat model of skin inflammation.
J Lipid Res. 2019; 60(4):758-766
Doi: 10.1194/jlr.M087221
[OPEN ACCESS]
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2018
Originalarbeit (Zeitschrift)
** Schimek, D; Raml, R; Francesconi, KA; Bodenlenz, M; Sinner, F
Quantification of acyclovir in dermal interstitial fluid and human serum by ultra-high-performance liquid-high-resolution tandem mass spectrometry for topical bioequivalence evaluation.
Biomed Chromatogr. 2018; 32(6):e4194-e4194
Doi: 10.1002/bmc.4194
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2017
Originalarbeit (Zeitschrift)
** Bodenlenz, M; Tiffner, KI; Raml, R; Augustin, T; Dragatin, C; Birngruber, T; Schimek, D; Schwagerle, G; Pieber, TR; Raney, SG; Kanfer, I; Sinner, F
Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence.
Clin Pharmacokinet. 2017; 56(1):91-98
Doi: 10.1007/s40262-016-0442-z
[OPEN ACCESS]
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** Kolbinger, F; Loesche, C; Valentin, MA; Jiang, X; Cheng, Y; Jarvis, P; Peters, T; Calonder, C; Bruin, G; Polus, F; Aigner, B; Lee, DM; Bodenlenz, M; Sinner, F; Pieber, TR; Patel, DD
β-Defensin 2 is a responsive biomarker of IL-17A-driven skin pathology in patients with psoriasis.
J Allergy Clin Immunol. 2017; 139(3):923-932
Doi: 10.1016/j.jaci.2016.06.038
[OPEN ACCESS]
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Korrektur
** Bodenlenz, M; Tiffner, KI; Raml, R; Augustin, T; Dragatin, C; Birngruber, T; Schimek, D; Schwagerle, G; Pieber, TR; Raney, SG; Kanfer, I; Sinner, F
Erratum to: Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence.
Clin Pharmacokinet. 2017; 56(1):99-99
Doi: 10.1007/s40262-016-0487-z
[OPEN ACCESS]
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Abstract (Zeitschrift)
** Birngruber, T; Prietl, B; Bodenlenz, M; Florian, P; Subramaniam, A; Kainz, S; Rauter, G; Pieber, TR; Sinner, F
Continuous sampling of immune cells in the skin by dermal open flow microperfusion
J INVEST DERMATOL. 2017; 137(10):S275-S275.-47th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR); SEP 27-30, 2017; Salzburg, AUSTRIA.
Doi: 10.1016/j.jid.2017.07.684
[Poster]
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** Bodenlenz, M; Prietl, B; Florian, P; Subramaniam, A; Kainz, S; Rauter, G; Pieber, TR; Sinner, F
Characterization of the Psoriasis-like Inflammation in the Imiquimod Rat Model using Dermal Open Flow Microperfusion
J INVEST DERMATOL. 2017; 137(10):S278-S278.-47th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR); SEP 27-30, 2017; Salzburg, AUSTRIA.
Doi: 10.1016/j.jid.2017.07.698
[Poster]
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2016
Originalarbeit (Zeitschrift)
** Bodenlenz, M; Dragatin, C; Liebenberger, L; Tschapeller, B; Boulgaropoulos, B; Augustin, T; Raml, R; Gatschelhofer, C; Wagner, N; Benkali, K; Rony, F; Pieber, T; Sinner, F
Kinetics of Clobetasol-17-Propionate in Psoriatic Lesional and Non-Lesional Skin Assessed by Dermal Open Flow Microperfusion with Time and Space Resolution.
Pharm Res. 2016; 33(9):2229-2238
Doi: 10.1007/s11095-016-1960-y
[OPEN ACCESS]
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Kurzbericht/Letter
** Dragatin, C; Polus, F; Bodenlenz, M; Calonder, C; Aigner, B; Tiffner, KI; Mader, JK; Ratzer, M; Woessner, R; Pieber, TR; Cheng, Y; Loesche, C; Sinner, F; Bruin, G
Secukinumab distributes into dermal interstitial fluid of psoriasis patients as demonstrated by open flow microperfusion.
Exp Dermatol. 2016; 25(2):157-159
Doi: 10.1111/exd.12863
[OPEN ACCESS]
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Abstract (Zeitschrift)
** Loesche, C; Kolbinger, F; Valentin, MA; Jarvis, P; Cheng, Y; Bruin, G; Polus, F; Aigner, B; Bodenlenz, M; Sinner, F; Pieber, TR; Patel, DD
beta-defensin-2 (BD-2) responds to a single dose of anti-IL-17A secukinumab in different skin layers of psoriatic patients within days
EXP DERMATOL. .. 2016; 25: 37-38.-2nd Inflammatroy Skin Disease Summit; NOV 16-19, 2016; New York, NY.
[Poster]
Web of Science
2015
Originalarbeit (Zeitschrift)
** Bodenlenz, M; Ellmerer, M; Schaupp, L; Jacobsen, LV; Plank, J; Brunner, GA; Wutte, A; Aigner, B; Mautner, SI; Pieber, TR
Bioavailability of insulin detemir and human insulin at the level of peripheral interstitial fluid in humans, assessed by open-flow microperfusion.
Diabetes Obes Metab. 2015; 17(12):1166-1172
Doi: 10.1111/dom.12551
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2014
Abstract (Zeitschrift)
** Bodenlenz, M; Dragatin, C; Benkali, K; Augustin, T; Hoefferer, C; Martel, P; Rony, F; Pieber, TR; Wagner, N; Sinner, F
Topical penetration of clobetasol-17-propionate into psoriatic lesional and non-lesional skin illustrated with time and space resolution by dermal open flow microperfusion
J INVEST DERMATOL. 2014; 134: S38-S38.-44th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR); SEP 10-13, 2014; Copenhagen, DENMARK.
[Poster]
Web of Science
** Bruin, G; Dragatin, C; Aigner, B; Polus, F; Calonder, C; Froeliger, C; Tiffner, K; Bodenlenz, M; Mader, J; Korsatko, S; Ratzer, M; Pieber, T; Loesche, C; Sinner, F
The anti IL-17A IgG1 antibody distributes in dermal interstitial fluid as demonstrated by using dermal open flow microperfusion after a single 300 mg subcutaneous administration; assessment in healthy volunteers and patients with moderate-to-severe plaque psoriasis
J INVEST DERMATOL. 2014; 134: S18-S18.-Annual Meeting of the Society-for-Investigative-Dermatology (SID); MAY 07-10, 2014; Albuquerque, NM.
[Poster]
Web of Science
2013
Originalarbeit (Zeitschrift)
** Bodenlenz, M; Aigner, B; Dragatin, C; Liebenberger, L; Zahiragic, S; Höfferer, C; Birngruber, T; Priedl, J; Feichtner, F; Schaupp, L; Korsatko, S; Ratzer, M; Magnes, C; Pieber, TR; Sinner, F
Clinical applicability of dOFM devices for dermal sampling.
Skin Res Technol. 2013; 19(4):474-483
Doi: 10.1111/srt.12071
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** Bodenlenz, M; Dragatin, C; Hoefferer, C; Birngruber, T; Priedl, J; Feichtner, F; Schaller, R; Aigner, B; Korsatko, S; Pieber, TR; Sinner, F
Certified dOFM sampling devices provide access to target tissue in pharmaceutical trials.
Biomed Tech (Berl). 2013; 58 Suppl 1(12):
Doi: 10.1515/bmt-2013-4133
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** Schwingenschuh, S; Hajnsek, M; Scharfetter, H; Martinsen, OG; Tiffner, K; Dragatin, C; Raml, R; Mautner, A; Bodenlenz, M; Sinner, F
Skin impedance measurements support ex-vivo penetration studies for topical applied drugs.
Biomed Tech (Berl). 2013; 58 Suppl 1(12):
Doi: 10.1515/bmt-2013-4420
[OPEN ACCESS]
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Abstract (Zeitschrift)
** Bruin, G; Dragatin, C; Aigner, B; Polus, F; Calonder, C; Froeliger, C; Tiffner, K; Bodenlenz, M; Mader, J; Korsatko, S; Ratzer, M; Pieber, TR; Loesche, C; Sinner, F;
Absolute levels of the novel anti-IL-17A antibody, secukinumab, in skin can be quantified by dermal open flow microperfusion (dOFM).
J INVEST DERMATOL. 2013; 133: S52-S52.-International Investigative Dermatology Meeting; MAY 08-11, 2013; Edinburgh, SCOTLAND.
[Poster]
Web of Science
Originalarbeit (Konferenzband)
** Schwingenschuh, S; Hajnsek, M; Scharfetter, H; Martinsen, OG; Tiffner, K; Dragatin, C; Raml, R; Mautner, A; Bodenlenz, M; Sinner, F
Skin impedance measurements support ex-vivo penetration studies for topical applied drugs
BIOMED ENG-BIOMED TE. 2013; 58:
Doi: 10.1515/bmt-2013-4420
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2012
Originalarbeit (Zeitschrift)
** Bodenlenz, M; Höfferer, C; Magnes, C; Schaller-Ammann, R; Schaupp, L; Feichtner, F; Ratzer, M; Pickl, K; Sinner, F; Wutte, A; Korsatko, S; Köhler, G; Legat, FJ; Benfeldt, EM; Wright, AM; Neddermann, D; Jung, T; Pieber, TR
Dermal PK/PD of a lipophilic topical drug in psoriatic patients by continuous intradermal membrane-free sampling.
Eur J Pharm Biopharm. 2012; 81(3):635-641
Doi: 10.1016/j.ejpb.2012.04.009
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** Holmgaard, R; Benfeldt, E; Nielsen, JB; Gatschelhofer, C; Sorensen, JA; Höfferer, C; Bodenlenz, M; Pieber, TR; Sinner, F
Comparison of open-flow microperfusion and microdialysis methodologies when sampling topically applied fentanyl and benzoic acid in human dermis ex vivo.
Pharm Res. 2012; 29(7):1808-1820
Doi: 10.1007/s11095-012-0705-9
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Abstract (Zeitschrift)
** Aigner, BA; Bodenlenz, M; Hofferer, C; Priedl, J; Dragatin, C; Kiefer, B; Korsatko, S; Liebenberger, L; Zahiragic, S; Raml, R; Magnes, C; Becker, JC; Pieber, TR; Sinner, F
Dermal open-flow microperfusion as a novel technique for in vivo measurement of dermal interstitium
EXP DERMATOL. 2012; 21(3):e13-e13.-39th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF); MAR 01-03, 2012; Marburg, GERMANY.
[Poster]
Web of Science
2011
Abstract (Zeitschrift)
** Bodenlenz, M; Hoefferer, C; Priedl, J; Dragatin, C; Korsatko, S; Liebenberger, L; Zahiragic, S; Raml, R; Magnes, C; Pieber, T; Sinner, F
A novel certified dermal sampling system for efficient clinical research
J INVEST DERMATOL. 2011; 131: S44-S44.
[Poster]
Web of Science
2010
Originalarbeit (Zeitschrift)
** Ikeoka, D; Pachler, C; Korsatko, S; Mader, JK; Weinhandl, H; Bodenlenz, M; Plank, J; Smolle, KH; Ellmerer, M; Pieber, TR
Interleukin-6 produced in subcutaneous adipose tissue is linked to blood pressure control in septic patients.
Cytokine. 2010; 50(3): 284-291.
Doi: 10.1016/j.cyto.2010.02.015
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2009
Originalarbeit (Zeitschrift)
** Ellmerer, M; Haluzik, M; Blaha, J; Kremen, J; Svacina, S; Plasnik, A; Ikeoka, D; Bodenlenz, M; Schaupp, L; Plank, J; Pieber, TR
Clinical evaluation of subcutaneous lactate measurement in patients after major cardiac surgery.
Int J Endocrinol. 2009; 2009(1):390975-390975
Doi: 10.1155/2009/390975
[OPEN ACCESS]
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** Schaller, R; Feichtner, F; Köhler, H; Bodenlenz, M; Plank, J; Wutte, A; Mader, JK; Ellmerer, M; Hellmich, R; Wedig, H; Hainisch, R; Pieber, TR; Schaupp, L
A novel automated discontinuous venous blood monitoring system for ex vivo glucose determination in humans.
Biosens Bioelectron. 2009; 24(7): 2239-2245.
Doi: 10.1016/j.bios.2008.11.029
Web of Science
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Abstract (Zeitschrift)
** Ikeoka, D; Korsatko, S; Pachler, C; Mader, JK; Smolle, KH; Bodenlenz, M; Plank, J; Ellmerer, M; Pieber, TR
INTERLEUKIN-6 PRODUCED IN ADIPOSE TISSUE IS STRONGLY LINKED TO DIASTOLIC BLOOD PRESSURE DURING SEVERE SEPSIS
INTENS CARE MED. 2009; 35: 0959--22nd Congress of the European Society of Intensive Care Medicine; OCT 11-14, 2009; Vienna, AUSTRIA.
[Poster]
Web of Science
2008
Originalarbeit (Zeitschrift)
** Horvath, K; Bock, G; Regittnig, W; Bodenlenz, M; Wutte, A; Plank, J; Magnes, C; Sinner, F; Fürst-Recktenwald, S; Theobald, K; Pieber, TR
Insulin glulisine, insulin lispro and regular human insulin show comparable end-organ metabolic effects: an exploratory study.
Diabetes Obes Metab. 2008; 10(6):484-491
Doi: 10.1111/j.1463-1326.2007.00734.x
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2007
Originalarbeit (Zeitschrift)
** Heise, HM; Damm, U; Bodenlenz, M; Kondepati, VR; Kohler, G; Ellmerer, M
Bedside monitoring of subcutaneous interstitial glucose in healthy individuals using microdialysis and infrared spectrometry
J BIOMED OPT. 2007; 12(2): 024004
Doi: 10.1117/1.2714907
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** Pickl, KE; Magnes, C; Bodenlenz, M; Pieber, TR; Sinner, FM
Rapid online-SPE-MS/MS method for ketoprofen determination in dermal interstitial fluid samples from rats obtained by microdialysis or open-flow microperfusion.
J Chromatogr B Analyt Technol Biomed Life Sci. 2007; 850(1-2):432-439
Doi: 10.1016/j.jchromb.2006.12.026
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** Wutte, A; Plank, J; Bodenlenz, M; Magnes, C; Regittnig, W; Sinner, F; Ronn, B; Zdravkovic, M; Pieber, TR
Proportional dose-response relationship and lower within-patient variability of insulin deternir and NPH insulin in subjects with type 1 diabetes mellitus
EXP CLIN ENDOCRINOL DIABETES. 2007; 115(7): 461-467.
Doi: 10.1055/s-2007-976512
Web of Science
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Kurzbericht/Letter
** Vlasselaers, D; Schaupp, L; van den Heuvel, I; Mader, J; Bodenlenz, M; Suppan, M; Wouters, P; Ellmerer, M; Van den Berghe, G
Monitoring blood glucose with microdialysis of interstitial fluid in critically ill children.
CLIN CHEM. 2007; 53(3): 536-537.
Doi: 10.1373/clinchem.2006.078089
[OPEN ACCESS]
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2006
Originalarbeit (Zeitschrift)
** Schaller, HC; Schaupp, L; Bodenlenz, M; Wilinska, ME; Chassin, LJ; Wach, P; Vering, T; Hovorka, R; Pieber, TR
On-line adaptive algorithm with glucose prediction capacity for subcutaneous closed loop control of glucose: evaluation under fasting conditions in patients with Type 1 diabetes.
DIABETIC MED. 2006; 23(1): 90-93.
Doi: 10.1111/j.1464-5491.2006.01695.x
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2005
Originalarbeit (Zeitschrift)
** Bodenlenz, M; Schaupp, LA; Druml, T; Sommer, R; Wutte, A; Schaller, HC; Sinner, F; Wach, P; Pieber, TR
Measurement of interstitial insulin in human adipose and muscle tissue under moderate hyperinsulinemia by means of direct interstitial access.
Am J Physiol Endocrinol Metab. 2005; 289(2):E296-E300
Doi: 10.1152/ajpendo.00431.2004
[OPEN ACCESS]
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** Plank, J; Bodenlenz, M; Sinner, F; Magnes, C; Görzer, E; Regittnig, W; Endahl, LA; Draeger, E; Zdravkovic, M; Pieber, TR
A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of the long-acting insulin analog detemir.
Diabetes Care. 2005; 28(5):1107-1112
Doi: 10.2337/diacare.28.5.1107
[OPEN ACCESS]
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2004
Originalarbeit (Zeitschrift)
** Hovorka, R; Chassin, LJ; Wilinska, ME; Canonico, V; Akwi, JA; Federici, MO; Massi-Benedetti, M; Hutzli, I; Zaugg, C; Kaufmann, H; Both, M; Vering, T; Schaller, HC; Schaupp, L; Bodenlenz, M; Pieber, TR
Closing the loop: the adicol experience.
Diabetes Technol Ther. 2004; 6(3): 307-318.
Doi: 10.1089/152091504774197990
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** Wilinska, ME; Bodenlenz, M; Chassin, LJ; Schaller, HC; Schaupp, LA; Pieber, TR; Hovorka, R
Interstitial glucose kinetics in subjects with type 1 diabetes under physiologic conditions.
METABOLISM. 2004; 53(11): 1484-1491.
Doi: 10.1016%2Fj.metabol.2004.05.014
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2003
Abstract (Zeitschrift)
** Bodenlenz, M; Sommer, R; Wutte, A; Druml, T; Sinner, F; Plank, J; Schaller, HC; Schaupp, L; Wach, P; Pieber, TR
Quantification of the human insulin concentration in adipose and muscle tissue of healthy subjects by means of the No-Net-Flux calibration technique and Open-Flow Microperfusion
DIABETOLOGIA 2003 46: 585-585.
Web of Science
2002
Abstract (Zeitschrift)
** Bodenlenz, M; Schaller, HC; Wutte, A; Jacobsen, LV; Druml, T; Meinitzer, A; Plank, J; Balent, B; Brandmair, H; Brunner, GA; Schaupp, L; Wach, P; Pieber, TR
Measurement of insulin detemir and human insulin in adipose and muscle tissue of diabetic patients using open-flow microperfusion.
DIABETOLOGIA 2002 45: 797-797.
Web of Science
** Schaupp, L; Schaller, HC; Bodenlenz, M; Haueter, U; Vering, T; Wutte, A; Plank, J; Sommer, R; Druml, T; Wach, P; Pieber, TR
Simultaneous glucose measurements in interstitial fluid with s.c. glucose sensors and open flow microperfusion in patients with Type 1 DM
DIABETOLOGIA 2002 45: 863-863.
Web of Science
2001
Abstract (Zeitschrift)
** Bodenlenz, M; Schaller, H; Wutte, A; Jacobsen, LV; Druml, T; Meinitzer, A; Plank, J; Brandmair, H; Brunner, GA; Schaupp, L; Wach, P; Pieber, TR
Measurement of insulin detemir and human insulin in adipose and muscle tissue using open-flow microperfusion.
DIABETOLOGIA 2001 44: 50-50.
Web of Science
** Schaupp, L; Brunner, GA; Schaller, H; Bodenlenz, M; Wutte, A; Wach, P; Pieber, TR
Glucose monitoring in the adipose tissue of type 1 diabetic patients using open-flow microperfusion and microdialysis
DIABETOLOGIA 2001 44: 174-174.
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