** = Publikationen gelistet in SCI/SSCI/Pubmed
** Föderl-Höbenreich, E; Panzitt, K
Ex vivo culture models to study viral infections of the liver.
Curr Opin Virol. 2025; 71:101462
Doi: 10.1016/j.coviro.2025.101462
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** Madreiter-Sokolowski, CT; Hiden, U; Krstic, J; Panzitt, K; Wagner, M; Enzinger, C; Khalil, M; Abdellatif, M; Malle, E; Madl, T; Osto, E; Schosserer, M; Binder, CJ; Olschewski, A
Targeting organ-specific mitochondrial dysfunction to improve biological aging.
Pharmacol Ther. 2024; 262:108710
Doi: 10.1016/j.pharmthera.2024.108710
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** Dean, AE; Jungwirth, E; Panzitt, K; Wagner, M; Anakk, S
Hepatic farnesoid X receptor is necessary to facilitate ductular reaction and expression of heme biosynthetic genes.
Hepatol Commun. 2023; 7(10):
Doi: 10.1097/HC9.0000000000000213
[OPEN ACCESS]
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** Panzitt, K; Zollner, G; Marschall, HU; Wagner, M
Recent advances on FXR-targeting therapeutics
MOL CELL ENDOCRINOL. 2022; 552: 111678
Doi: 10.1016/j.mce.2022.111678
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** Wagner, M; Jungwirth, E; Panzitt, K; Moore, D; Madl, T; Thallinger, G; Marschall, HU
FXR binding and transcription in the liver is signficantly altered in obese patients with NAFLD
J HEPATOL. 2022; 77: S696-S697.-European Association for the Studies of the Liver - EASL; Jun 22-25, 2022; London, Great Britain.
[Poster]
Web of Science
** Greimel, T; Jahnel, J; Pohl, S; Strini, T; Tischitz, M; Meier-Allard, N; Holasek, S; Meinel, K; Aguiriano-Moser, V; Zobel, J; Haidl, H; Gallistl, S; Panzitt, K; Wagner, M; Schlagenhauf, A
Bile acid-induced tissue factor activity in hepatocytes correlates with activation of farnesoid X receptor.
Lab Invest. 2021; 101(10):1394-1402
Doi: 10.1038/s41374-021-00628-z
[OPEN ACCESS]
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** Guelly, C; Abilova, Z; Nuralinov, O; Panzitt, K; Akhmetova, A; Rakhimova, S; Kozhamkulov, U; Kairov, U; Molkenov, A; Seisenova, A; Trajanoski, S; Abildinova Rashbayeva, G; Kaussova, G; Windpassinger, C; Lee, JH; Zhumadilov, Z; Bekbossynova, M; Akilzhanova, A
Patients with coronary heart disease, dilated cardiomyopathy and idiopathic ventricular tachycardia share overlapping patterns of pathogenic variation in cardiac risk genes.
PeerJ. 2021; 9: e10711-e10711.
Doi: 10.7717/peerj.10711
[OPEN ACCESS]
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** Jungwirth, E; Panzitt, K; Marschall, HU; Thallinger, GG; Wagner, M
Meta-analysis and Consolidation of Farnesoid X Receptor Chromatin Immunoprecipitation Sequencing Data Across Different Species and Conditions
HEPATOL COMMUN. 2021;
Doi: 10.1002/hep4.1749
[OPEN ACCESS]
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** Panzitt, K; Fickert, P; Wagner, M
Regulation of autophagy by bile acids and in cholestasis - CholestoPHAGY or CholeSTOPagy.
Biochim Biophys Acta Mol Basis Dis. 2021; 1867(2):166017-166017
Doi: 10.1016/j.bbadis.2020.166017
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** Panzitt, K; Wagner, M
FXR in liver physiology: Multiple faces to regulate liver metabolism
BBA-MOL BASIS DIS. 2021; 1867(7): 166133
Doi: 10.1016/j.bbadis.2021.166133
[OPEN ACCESS]
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** Panzitt, K; Jungwirth, E; Krones, E; Lee, JM; Pollheimer, M; Thallinger, GG; Kolb-Lenz, D; Xiao, R; Thorell, A; Trauner, M; Fickert, P; Marschall, HU; Moore, DD; Wagner, M
FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
J Hepatol. 2020; 72(6):1122-1131
Doi: 10.1016/j.jhep.2020.01.014
[OPEN ACCESS]
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** Seidl, C; Panzitt, K; Bertsch, A; Brcic, L; Schein, S; Mack, M; Leithner, K; Prinz, F; Olschewski, H; Kornmueller, K; Hrzenjak, A
MicroRNA-182-5p regulates hedgehog signaling pathway and chemosensitivity of cisplatin-resistant lung adenocarcinoma cells via targeting GLI2.
Cancer Lett. 2020; 469: 266-276.
Doi: 10.1016/j.canlet.2019.10.044
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** Al-Dury, S; Wahlström, A; Panzitt, K; Thorell, A; Ståhlman, M; Trauner, M; Fickert, P; Bäckhed, F; Fändriks, L; Wagner, M; Marschall, HU
Obeticholic acid may increase the risk of gallstone formation in susceptible patients.
J Hepatol. 2019; 71(5):986-991
Doi: 10.1016/j.jhep.2019.06.011
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** Klec, C; Gutschner, T; Panzitt, K; Pichler, M
Involvement of long non-coding RNA HULC (highly up-regulated in liver cancer) in pathogenesis and implications for therapeutic intervention.
Expert Opin Ther Targets. 2019; 23(3): 177-186.
Doi: 10.1080/14728222.2019.1570499
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** Liu, L; Panzitt, K; Racedo, S; Wagner, M; Platzer, W; Zaufel, A; Theiler-Schwetz, V; Obermayer-Pietsch, B; Müller, H; Höfler, G; Heinemann, A; Zollner, G; Fickert, P
Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1PR2, ERK and SF-1.
Liver Int. 2019; 39(11):2112-2123
Doi: 10.1111/liv.14052
[OPEN ACCESS]
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** Al-Dury, S; Wahlstrom, A; Panzitt, K; Thorell, A; Stahlman, M; Trauner, MH; Fickert, P; Backhed, F; Fandriks, L; Wagner, M; Marschall, HU
Obeticholic Acid Increases Cholesterol Saturation and FGF19 in Human Gallbladder Bile
HEPATOLOGY. 2018; 68: 159A-159A.-Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting; NOV 09-13, 2018; San Francisco, CA.
[Oral Communication]
Web of Science
** Fadejeva, I; Bertsch, A; Panzitt, K; Leithner, K; Olschewski, H; Hrzenjak, A
MicroRNA expression in A549 NSCLC cells and non-malignant bronchial epithelial cells under normoxic and hypoxic conditions
WIEN KLIN WOCHENSCHR. 2018; 130(19-20):601-602.-Jahrestagung der Österreichischen Gesellschaft für Pneumologie (ÖGP); OKT 18-20, 2018; Linz, AUSTRIA.
[Poster]
Web of Science
** Kaushik, AK; Shojaie, A; Panzitt, K; Sonavane, R; Venghatakrishnan, H; Manikkam, M; Zaslavsky, A; Putluri, V; Vasu, VT; Zhang, Y; Khan, AS; Lloyd, S; Szafran, AT; Dasgupta, S; Bader, DA; Stossi, F; Li, H; Samanta, S; Cao, X; Tsouko, E; Huang, S; Frigo, DE; Chan, L; Edwards, DP; Kaipparettu, BA; Mitsiades, N; Weigel, NL; Mancini, M; McGuire, SE; Mehra, R; Ittmann, MM; Chinnaiyan, AM; Putluri, N; Palapattu, GS; Michailidis, G; Sreekumar, A
Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer.
Nat Commun. 2016; 7(7):11612-11612
Doi: 10.1038/ncomms11612
[OPEN ACCESS]
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** Wagner, M; Choi, S; Panzitt, K; Mamrosh, JL; Lee, JM; Zaufel, A; Xiao, R; Wooton-Kee, R; Ståhlman, M; Newgard, CB; Borén, J; Moore, DD
Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism.
Hepatology. 2016; 63(1):95-106
Doi: 10.1002/hep.28124
[OPEN ACCESS]
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** Panzitt, K; Marschall, HU; Moore, DD; Trauner, MH; Fickert, P; Wagner, M
The autophagy inhibitor Rubicon is a direct target of the bile acid receptor FXR in human liver and is induced in human cholestasis
HEPATOLOGY. 2016; 63(1 SUPP):159A-159A.-67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 11-15, 2016; Boston, MA.
[Poster]
Web of Science
** Schuller, M; Wagner, M; Panzitt, K
Endogenous phosphatidylcholine generation via the PEMT pathway modulates LRH-1 signaling - Dietary clues for treating NAFLD?
WIEN KLIN WOCHENSCHR. 2016; 128: S383-S384.
[Poster]
Web of Science
** Panzitt, K; Marschall, HU; Trauner, M; Fickert, P; Wagner, M
Effects of Ursodeoxycholic-acid and Rifampicin on autophagy in the liver
HEPATOLOGY. . 2015; 62: 538A-538A.-66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 13-17, 2015; San Francisco, CA.
[Oral Communication]
Web of Science
** Kaushik, AK; Vareed, SK; Basu, S; Putluri, V; Putluri, N; Panzitt, K; Brennan, CA; Chinnaiyan, AM; Vergara, IA; Erho, N; Weigel, NL; Mitsiades, N; Shojaie, A; Palapattu, G; Michailidis, G; Sreekumar, A
Metabolomic profiling identifies biochemical pathways associated with castration-resistant prostate cancer.
J Proteome Res. 2014; 13(2):1088-1100
Doi: 10.1021/pr401106h
[OPEN ACCESS]
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** Putluri, N; Shojaie, A; Vasu, VT; Vareed, SK; Nalluri, S; Putluri, V; Thangjam, GS; Panzitt, K; Tallman, CT; Butler, C; Sana, TR; Fischer, SM; Sica, G; Brat, DJ; Shi, H; Palapattu, GS; Lotan, Y; Weizer, AZ; Terris, MK; Shariat, SF; Michailidis, G; Sreekumar, A
Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression.
Cancer Res. 2011; 71(24):7376-7386
Doi: 10.1158/0008-5472.CAN-11-1154
[OPEN ACCESS]
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** Schmid, K; Schuller, M; Panzitt, K; Zatloukal, K; van der Nest, DG; van Griensven, KN; Redl, H; Schmidt-Gann, G
Comparison of gene expression patterns in Gram plus versus Gram-induced sepsis using different approaches
SHOCK. 2008; 29: 105-106.
Web of Science
** Panzitt, K; Tschernatsch, MM; Guelly, C; Moustafa, T; Stradner, M; Strohmaier, HM; Buck, CR; Denk, H; Schroeder, R; Trauner, M; Zatloukal, K
Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA.
Gastroenterology. 2007; 132(1):330-342
Doi: 10.1053/j.gastro.2006.08.026
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Google Scholar
** Panzitt, K; Strohmaier, HM; Moustafa, T; Stradner, M; Gully, C; Buck, CR; Denk, H; Zatloukal, K
A non-protein-coding RNA is a major deregulated gene in hepatocellular carcinoma and may act as a general modulator of gene expression
HEPATOLOGY 2004 40: 253A-253A.
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