** = Publikationen gelistet in SCI/SSCI/Pubmed
** Akhmetshina, A; Schooltink, L; Amor, M; Kuentzel, KB; Rainer, S; Nandy, A; Habisch, H; Madl, T; Rendina-Ruedy, E; Leithner, K; Vujić, N; Kratky, D
Loss or inhibition of lysosomal acid lipase in vitro leads to cholesteryl ester accumulation without affecting muscle formation or mitochondrial function.
BBA Adv. 2025; 7: 100135
Doi: 10.1016/j.bbadva.2024.100135
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** Akhmetshina, A; Bianco, V; Bradić, I; Korbelius, M; Pirchheim, A; Kuentzel, KB; Eichmann, TO; Hinteregger, H; Kolb, D; Habisch, H; Liesinger, L; Madl, T; Sattler, W; Radović, B; Sedej, S; Birner-Gruenberger, R; Vujić, N; Kratky, D
Loss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles of mice.
Mol Metab. 2024; 79:101869
Doi: 10.1016/j.molmet.2023.101869
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** Bradić, I; Vujić, N; Kuentzel, KB; Habisch, H; Pirchheim, A; Akhmetshina, A; Henderson, JD; Madl, T; Deshmukh, AS; Kratky, D
Lanifibranor Reduces Inflammation and Improves Dyslipidemia in Lysosomal Acid Lipase-Deficient Mice.
Gastro Hep Adv. 2024; 3(6): 711-723.
Doi: 10.1016/j.gastha.2024.05.006
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** Buerger, M; Amor, M; Akhmetshina, A; Bianco, V; Perfler, B; Zebisch, A; Weichhart, T; Kratky, D
Limited Alleviation of Lysosomal Acid Lipase Deficiency by Deletion of Matrix Metalloproteinase 12.
Int J Mol Sci. 2024; 25(20): 11001
Doi: 10.3390/ijms252011001
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** Amor, M; Bianco, V; Buerger, M; Lechleitner, M; Vujić, N; Dobrijević, A; Akhmetshina, A; Pirchheim, A; Schwarz, B; Pessentheiner, AR; Baumgartner, F; Rampitsch, K; Schauer, S; Klobučar, I; Degoricija, V; Pregartner, G; Kummer, D; Svecla, M; Sommer, G; Kolb, D; Holzapfel, GA; Hoefler, G; Frank, S; Norata, GD; Kratky, D
Genetic deletion of MMP12 ameliorates cardiometabolic disease by improving insulin sensitivity, systemic inflammation, and atherosclerotic features in mice.
Cardiovasc Diabetol. 2023; 22(1): 327
Doi: 10.1186/s12933-023-02064-3
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** Bianco, V; Korbelius, M; Vujic, N; Akhmetshina, A; Amor, M; Kolb, D; Pirchheim, A; Bradic, I; Kuentzel, KB; Buerger, M; Schauer, S; Phan, HTT; Bulfon, D; Hoefler, G; Zimmermann, R; Kratky, D
Impact of (intestinal) LAL deficiency on lipid metabolism and macrophage infiltration.
Mol Metab. 2023; 73: 101737
Doi: 10.1016/j.molmet.2023.101737
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** Nandy, A; Richards, A; Thapa, S; Akhmetshina, A; Narayani, N; Rendina-Ruedy, E
Altered Osteoblast Metabolism with Aging Results in Lipid Accumulation and Oxidative Stress Mediated Bone Loss.
AGING DIS. 2023;
Doi: 10.14336/AD.2023.0510
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** Akhmetshina, A; Kratky, D; Rendina-Ruedy, E
Influence of Cholesterol on the Regulation of Osteoblast Function.
Metabolites. 2023; 13(4):
Doi: 10.3390/metabo13040578
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** Zhou, Q; Kerbl-Knapp, J; Zhang, F; Korbelius, M; Kuentzel, KB; Vujić, N; Akhmetshina, A; Hörl, G; Paar, M; Steyrer, E; Kratky, D; Madl, T
Metabolomic Profiles of Mouse Tissues Reveal an Interplay between Aging and Energy Metabolism.
Metabolites. 2021; 12(1):
Doi: 10.3390/metabo12010017
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** Zhou, Q; Zhang, F; Kerbl-Knapp, J; Korbelius, M; Kuentzel, KB; Vujić, N; Akhmetshina, A; Hörl, G; Paar, M; Steyrer, E; Kratky, D; Madl, T
Phosphatidylethanolamine N-Methyltransferase Knockout Modulates Metabolic Changes in Aging Mice.
BIOMOLECULES. 2022; 12(9):
Doi: 10.3390/biom12091270
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** Bianco, V; Korbelius, M; Vujic, N; Akhmetshina, A; Kolb, D; Kratky, D
CONSEQUENCES OF (INTESTINAL) LAL DEFICIENCY ON WHOLE BODY LIPID METABOLISM
ATHEROSCLEROSIS. 2022; 355: E42-E42.-EAS Congress 2022; May 22-25, 2022; Milan.
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** Helderman, RC; Whitney, DG; Duta-Mare, M; Akhmetshina, A; Vujic, N; Jayapalan, S; Nyman, JS; Misra, BB; Rosen, CJ; Czech, MP; Kratky, D; Rendina-Ruedy, E
Loss of function of lysosomal acid lipase (LAL) profoundly impacts osteoblastogenesis and increases fracture risk in humans.
Bone. 2021; 148:115946
Doi: 10.1016/j.bone.2021.115946
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** Kuentzel, KB; Bradić, I; Akhmetshina, A; Korbelius, M; Rainer, S; Kolb, D; Gauster, M; Vujić, N; Kratky, D
Defective Lysosomal Lipolysis Causes Prenatal Lipid Accumulation and Exacerbates Immediately after Birth.
Int J Mol Sci. 2021; 22(19):
Doi: 10.3390/ijms221910416
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** Zhang, F; Kerbl-Knapp, J; Akhmetshina, A; Korbelius, M; Kuentzel, KB; Vujić, N; Hörl, G; Paar, M; Kratky, D; Steyrer, E; Madl, T
Tissue-Specific Landscape of Metabolic Dysregulation during Ageing.
Biomolecules. 2021; 11(2):
Doi: 10.3390/biom11020235
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** Zhang, F; Kerbl-Knapp, J; Rodriguez Colman, MJ; Meinitzer, A; Macher, T; Vujic, N; Fasching, S; Jany-Luig, E; Korbelius, M; Kuentzel, KB; Mack, M; Akhmetshina, A; Pirchheim, A; Paar, M; Rinner, B; Hörl, G; Steyrer, E; Stelzl, U; Burgering, B; Eisenberg, T; Pertschy, B; Kratky, D; Madl, T.
Global analysis of protein arginine methylation.
Cell reports methods. 2021; 1(2):
Doi: 10.1016/j.crmeth.2021.100016
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** Zakharova, IO; Sokolova, TV; Akhmetshina, AO; Avrova, NF
Role of Protein Kinase Akt Activation in Protective Effect of Ganglioside GM1 on PC12 Cells Exposed to H2O2.
Bull Exp Biol Med. 2015; 159(5): 610-613.
Doi: 10.1007/s10517-015-3026-2
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