** = Publikationen gelistet in SCI/SSCI/Pubmed
** Akhmetshina, A; Schooltink, L; Amor, M; Kuentzel, KB; Rainer, S; Nandy, A; Habisch, H; Madl, T; Rendina-Ruedy, E; Leithner, K; Vujić, N; Kratky, D
Loss or inhibition of lysosomal acid lipase in vitro leads to cholesteryl ester accumulation without affecting muscle formation or mitochondrial function.
BBA Adv. 2025; 7: 100135
Doi: 10.1016/j.bbadva.2024.100135
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** Bradić, I; Kuentzel, KB; Pirchheim, A; Rainer, S; Schwarz, B; Trauner, M; Larsen, MR; Vujić, N; Kratky, D
From LAL-D to MASLD: Insights into the role of LAL and Kupffer cells in liver inflammation and lipid metabolism.
Biochim Biophys Acta Mol Cell Biol Lipids. 2024; 159575
Doi: 10.1016/j.bbalip.2024.159575
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** Akhmetshina, A; Bianco, V; Bradić, I; Korbelius, M; Pirchheim, A; Kuentzel, KB; Eichmann, TO; Hinteregger, H; Kolb, D; Habisch, H; Liesinger, L; Madl, T; Sattler, W; Radović, B; Sedej, S; Birner-Gruenberger, R; Vujić, N; Kratky, D
Loss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles of mice.
Mol Metab. 2024; 79:101869
Doi: 10.1016/j.molmet.2023.101869
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** Bradić, I; Vujić, N; Kuentzel, KB; Habisch, H; Pirchheim, A; Akhmetshina, A; Henderson, JD; Madl, T; Deshmukh, AS; Kratky, D
Lanifibranor Reduces Inflammation and Improves Dyslipidemia in Lysosomal Acid Lipase-Deficient Mice.
Gastro Hep Adv. 2024; 3(6): 711-723.
Doi: 10.1016/j.gastha.2024.05.006
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** Bianco, V; Korbelius, M; Vujic, N; Akhmetshina, A; Amor, M; Kolb, D; Pirchheim, A; Bradic, I; Kuentzel, KB; Buerger, M; Schauer, S; Phan, HTT; Bulfon, D; Hoefler, G; Zimmermann, R; Kratky, D
Impact of (intestinal) LAL deficiency on lipid metabolism and macrophage infiltration.
Mol Metab. 2023; 73: 101737
Doi: 10.1016/j.molmet.2023.101737
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** Bradić, I; Liesinger, L; Kuentzel, KB; Vujić, N; Trauner, M; Birner-Gruenberger, R; Kratky, D
Metabolic changes and propensity for inflammation, fibrosis, and cancer in livers of mice lacking lysosomal acid lipase.
J Lipid Res. 2023; 64(9):100427
Doi: 10.1016/j.jlr.2023.100427
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** Goeritzer, M; Kuentzel, KB; Beck, S; Korbelius, M; Rainer, S; Bradić, I; Kolb, D; Mussbacher, M; Schrottmaier, WC; Assinger, A; Schlagenhauf, A; Rost, R; Gottschalk, B; Eichmann, TO; Züllig, T; Graier, WF; Vujić, N; Kratky, D
Monoglyceride Lipase Deficiency Is Associated with Altered Thrombogenesis in Mice.
Int J Mol Sci. 2023; 24(4): 3116
Doi: 10.3390/ijms24043116
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** Korbelius, M; Kuentzel, KB; Bradić, I; Vujić, N; Kratky, D
Recent insights into lysosomal acid lipase deficiency.
Trends Mol Med. 2023; 29(6):425-438
Doi: 10.1016/j.molmed.2023.03.001
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** Bradić, I; Kuentzel, KB; Honeder, S; Grabner, GF; Vujić, N; Zimmermann, R; Birner-Gruenberger, R; Kratky, D
Off-target effects of the lysosomal acid lipase inhibitors Lalistat-1 and Lalistat-2 on neutral lipid hydrolases.
Mol Metab. 2022; 61:101510
Doi: 10.1016/j.molmet.2022.101510
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** Goeritzer, M; Schlager, S; Kuentzel, KB; Vujić, N; Korbelius, M; Rainer, S; Kolb, D; Mussbacher, M; Salzmann, M; Schrottmaier, WC; Assinger, A; Schlagenhauf, A; Madreiter-Sokolowski, CT; Blass, S; Eichmann, TO; Graier, WF; Kratky, D
Adipose Triglyceride Lipase Deficiency Attenuates In Vitro Thrombus Formation without Affecting Platelet Activation and Bleeding In Vivo.
Cells. 2022; 11(5):
Doi: 10.3390/cells11050850
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** Korbelius, M; Vujić, N; Kuentzel, KB; Obrowsky, S; Rainer, S; Haemmerle, G; Rülicke, T; Kratky, D
Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis.
Biochim Biophys Acta Mol Cell Biol Lipids. 2022; 1867(4): 159121
Doi: 10.1016/j.bbalip.2022.159121
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** Kuentzel, KB; Bradić, I; Mihalič, ZN; Korbelius, M; Rainer, S; Pirchheim, A; Kargl, J; Kratky, D
Dysregulation of Placental Lipid Hydrolysis by High-Fat/High-Cholesterol Feeding and Gestational Diabetes Mellitus in Mice.
Int J Mol Sci. 2022; 23(20): 12286
Doi: 10.3390/ijms232012286
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** Zhou, Q; Kerbl-Knapp, J; Zhang, F; Korbelius, M; Kuentzel, KB; Vujić, N; Akhmetshina, A; Hörl, G; Paar, M; Steyrer, E; Kratky, D; Madl, T
Metabolomic Profiles of Mouse Tissues Reveal an Interplay between Aging and Energy Metabolism.
Metabolites. 2021; 12(1):
Doi: 10.3390/metabo12010017
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** Zhou, Q; Zhang, F; Kerbl-Knapp, J; Korbelius, M; Kuentzel, KB; Vujić, N; Akhmetshina, A; Hörl, G; Paar, M; Steyrer, E; Kratky, D; Madl, T
Phosphatidylethanolamine N-Methyltransferase Knockout Modulates Metabolic Changes in Aging Mice.
BIOMOLECULES. 2022; 12(9):
Doi: 10.3390/biom12091270
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** Vos, DY; Heida, A; Koster, M; Tissink, J; Kuentzel, KB; Kloosterhuis, NJ; Smit, M; Huijkman, N; Reggiori, F; Mari, M; Scheja, L; Heeren, J; Kratky, D; Kuivenhoven, J; Van De Sluis, B
THE ENDOSOMAL SORTING PROTEIN VPS35 CONTROLS LIPID HOMEOSTASIS THROUGH REGULATING HEPATIC LYSOSOMAL FUNCTION
ATHEROSCLEROSIS. 2022; 355: E50-E51.-EAS Congress 2022; May 22-25, 2022; Milan.
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** Kuentzel, KB; Bradić, I; Akhmetshina, A; Korbelius, M; Rainer, S; Kolb, D; Gauster, M; Vujić, N; Kratky, D
Defective Lysosomal Lipolysis Causes Prenatal Lipid Accumulation and Exacerbates Immediately after Birth.
Int J Mol Sci. 2021; 22(19):
Doi: 10.3390/ijms221910416
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** Vujić, N; Bradić, I; Goeritzer, M; Kuentzel, KB; Rainer, S; Kratky, D; Radović, B
ATG7 is dispensable for LC3-PE conjugation in thioglycolate-elicited mouse peritoneal macrophages.
Autophagy. 2021; 17(11):3402-3407
Doi: 10.1080/15548627.2021.1874132
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** Zhang, F; Kerbl-Knapp, J; Akhmetshina, A; Korbelius, M; Kuentzel, KB; Vujić, N; Hörl, G; Paar, M; Kratky, D; Steyrer, E; Madl, T
Tissue-Specific Landscape of Metabolic Dysregulation during Ageing.
Biomolecules. 2021; 11(2):
Doi: 10.3390/biom11020235
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** Zhang, F; Kerbl-Knapp, J; Rodriguez Colman, MJ; Meinitzer, A; Macher, T; Vujic, N; Fasching, S; Jany-Luig, E; Korbelius, M; Kuentzel, KB; Mack, M; Akhmetshina, A; Pirchheim, A; Paar, M; Rinner, B; Hörl, G; Steyrer, E; Stelzl, U; Burgering, B; Eisenberg, T; Pertschy, B; Kratky, D; Madl, T.
Global analysis of protein arginine methylation.
Cell reports methods. 2021; 1(2):
Doi: 10.1016/j.crmeth.2021.100016
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** Kuentzel, KB; Korbelius, M; Bradic, I; Vujic, N; Gauster, M; Wadsack, C; Kratky, D
HOW DOES THE LOSS OF INTRACELLULAR LIPASES AFFECT MOUSE PLACENTA AND FETUS?
PLACENTA. 2021; 112: E73-E73.-IFPA 2021; AUG 30 - SEP 2, 2021; Amsterdam, Netherlands.
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