Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Sconocchia Tommaso |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2025
Originalarbeit (Zeitschrift)
** Foßelteder, J; Brauchart, T; Schlacher, A; Sconocchia, T; Özkaya, E; Auinger, L; Schlenke, P; Sill, H; Zebisch, A; Reinisch, A
Engineered cytokine-expressing MSCs support ex vivo culture of human HSPCs and AML cells.
Exp Hematol. 2025; 104790
Doi: 10.1016/j.exphem.2025.104790
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2023
Originalarbeit (Zeitschrift)
** Foßelteder, J; Pabst, G; Sconocchia, T; Schlacher, A; Auinger, L; Kashofer, K; Beham-Schmid, C; Trajanoski, S; Waskow, C; Schöll, W; Sill, H; Zebisch, A; Wölfler, A; Thomas, D; Reinisch, A
Human gene-engineered calreticulin mutant stem cells recapitulate MPN hallmarks and identify targetable vulnerabilities.
Leukemia. 2023; 37(4): 843-853.
Doi: 10.1038/s41375-023-01848-6
[OPEN ACCESS]
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** Sconocchia, T; Foßelteder, J; Auinger, L; Özkaya, E; Benezeder, T; Lang, M; Beham-Schmid, C; Hoefler, G; Zebisch, A; Wölfler, A; Sill, H; Wolf, P; Strobl, H; Reinisch, A
BRAFV600E promotes DC3/monocyte differentiation in human gene-engineered HSPCs and causes multisystem histiocytosis.
Leukemia. 2023; 37(11): 2292-2296.
Doi: 10.1038/s41375-023-02019-3
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** Sconocchia, T; Foßelteder, J; Köhnke, T; Majeti, R; Reinisch, A
Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells.
J Vis Exp. 2023; (193): e64558
Doi: 10.3791/64558
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Übersichtsarbeit
** Aureli, A; Marziani, B; Venditti, A; Sconocchia, T; Sconocchia, G
Acute Lymphoblastic Leukemia Immunotherapy Treatment: Now, Next, and Beyond.
Cancers (Basel). 2023; 15(13):
Doi: 10.3390/cancers15133346
[OPEN ACCESS]
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** Sconocchia, T; Foßelteder, J; Sconocchia, G; Reinisch, A
Langerhans cell histiocytosis: current advances in molecular pathogenesis.
Front Immunol. 2023; 14: 1275085
Doi: 10.3389/fimmu.2023.1275085
[OPEN ACCESS]
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2022
Originalarbeit (Zeitschrift)
** Lackner, S; Sconocchia, T; Ziegler, T; Passegger, C; Meier-Allard, N; Schwarzenberger, E; Wonisch, W; Lahousen, T; Kohlhammer-Dohr, A; Mörkl, S; Derler, M; Strobl, H; Holasek, SJ
Immunomodulatory Effects of Aronia Juice Polyphenols-Results of a Randomized Placebo-Controlled Human Intervention Study and Cell Culture Experiments.
Antioxidants (Basel). 2022; 11(7):
Doi: 10.3390/antiox11071283
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** Sconocchia, G; Lanzilli, G; Cesarini, V; Silvestris, DA; Rezvani, K; Arriga, R; Caratelli, S; Chen, K; Dou, J; Cenciarelli, C; Toietta, G; Baldari, S; Sconocchia, T; De, Paolis, F; Aureli, A; Iezzi, G; Irno, Consalvo, M; Buccisano, F; Del, Principe, MI; Maurillo, L; Venditti, A; Ottaviani, A; Spagnoli, GC
Direct CD32 T-cell cytotoxicity: implications for breast cancer prognosis and treatment.
Life Sci Alliance. 2022; 5(12):
Doi: 10.26508/lsa.202201590
[OPEN ACCESS]
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2021
Originalarbeit (Zeitschrift)
** Sconocchia, T; Hochgerner, M; Schwarzenberger, E; Tam-Amersdorfer, C; Borek, I; Benezeder, T; Bauer, T; Zyulina, V; Painsi, C; Passegger, C; Wolf, P; Sibilia, M; Strobl, H
Bone morphogenetic protein signaling regulates skin inflammation via modulating dendritic cell function.
J Allergy Clin Immunol. 2021; 147(5):1810-1822
Doi: 10.1016/j.jaci.2020.09.038
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** Zyulina, V; Yan, KK; Ju, B; Schwarzenberger, E; Passegger, C; Tam-Amersdorfer, C; Pan, Q; Sconocchia, T; Pollack, C; Shaner, B; Zebisch, A; Easton, J; Yu, J; Silva, JM; Strobl, H
The miR-424(322)/503 gene cluster regulates pro- versus anti-inflammatory skin DC subset differentiation by modulating TGF-β signaling.
Cell Rep. 2021; 35(4): 109049-109049.
Doi: 10.1016/j.celrep.2021.109049
[OPEN ACCESS]
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Kurzbericht/Letter
** Sconocchia, T; Del, Gaudio, I; Meshcheryakova, A; Mechtcheriakova, D; Wadsack, C; Strobl, H
Induction of the sphingosine-1-phosphate signaling pathway by TGF-β1 during Langerhans-type dendritic cell differentiation.
Eur J Immunol. 2021; 51(7): 1854-1856.
Doi: 10.1002/eji.202049013
[OPEN ACCESS]
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Übersichtsarbeit
** Aureli, A; Marziani, B; Sconocchia, T; Del, Principe, MI; Buzzatti, E; Pasqualone, G; Venditti, A; Sconocchia, G
Immunotherapy as a Turning Point in the Treatment of Acute Myeloid Leukemia.
Cancers (Basel). 2021; 13(24):
Doi: 10.3390/cancers13246246
[OPEN ACCESS]
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** Sconocchia, T; Sconocchia, G
Regulation of the Immune System in Health and Disease by Members of the Bone Morphogenetic Protein Family.
Front Immunol. 2021; 12:802346
Doi: 10.3389/fimmu.2021.802346
[OPEN ACCESS]
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2020
Originalarbeit (Zeitschrift)
** Arriga, R; Caratelli, S; Lanzilli, G; Ottaviani, A; Cenciarelli, C; Sconocchia, T; Spagnoli, GC; Iezzi, G; Roselli, M; Lauro, D; Coppola, A; Dotti, G; Ferrone, S; Sconocchia, G
CD16-158-valine chimeric receptor T cells overcome the resistance of KRAS-mutated colorectal carcinoma cells to cetuximab.
Int J Cancer. 2020; 146(9):2531-2538
Doi: 10.1002/ijc.32618
[OPEN ACCESS]
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** Borek, I; Köffel, R; Feichtinger, J; Spies, M; Glitzner-Zeis, E; Hochgerner, M; Sconocchia, T; Krump, C; Tam-Amersdorfer, C; Passegger, C; Benezeder, T; Tittes, J; Redl, A; Painsi, C; Thallinger, GG; Wolf, P; Stary, G; Sibilia, M; Strobl, H
BMP7 aberrantly induced in the psoriatic epidermis instructs inflammation-associated Langerhans cells.
J Allergy Clin Immunol. 2020; 145(4): 1194-1207.
Doi: 10.1016/j.jaci.2019.12.011
[OPEN ACCESS]
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** Caratelli, S; Arriga, R; Sconocchia, T; Ottaviani, A; Lanzilli, G; Pastore, D; Cenciarelli, C; Venditti, A; Del Principe, MI; Lauro, D; Landoni, E; Du, H; Savoldo, B; Ferrone, S; Dotti, G; Sconocchia, G
In vitro elimination of epidermal growth factor receptor-overexpressing cancer cells by CD32A-chimeric receptor T cells in combination with cetuximab or panitumumab.
Int J Cancer. 2020; 146(1):236-247
Doi: 10.1002/ijc.32663
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2019
Übersichtsarbeit
** Marei, HE; Althani, A; Caceci, T; Arriga, R; Sconocchia, T; Ottaviani, A; Lanzilli, G; Roselli, M; Caratelli, S; Cenciarelli, C; Sconocchia, G
Recent perspective on CAR and Fcγ-CR T cell immunotherapy for cancers: Preclinical evidence versus clinical outcomes.
BIOCHEM PHARMACOL. 2019; 166(9): 335-346.
Doi: 10.1016/j.bcp.2019.06.002
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Abstract (Zeitschrift)
** Hochgerner, M; Bauer, T; Borek, I; Sconocchia, T; Warsi, S; Karlsson, S; Sibilia, M; Strobl, H
Differing Roles for BMPR1a and BMPR2 in Development and Function of Langerhans Cells
EUR J IMMUNOL. 2019; 49: 23-23.-16th International Workshop on Langerhans Cells (LC); OCT 03-06, 2019; Mainz, GERMANY.
[Poster]
Web of Science
** Sconocchia, T; Hochgerner, M; Borek, I; Schwarzenberger, E; Tam-Amersdorfer, C; Strobl, H
BMP signaling promotes regulatory T cell generation during skin inflammation via DC-dependent and independent mechanisms
EUR J IMMUNOL. 2019; 49: 8-8.-16th International Workshop on Langerhans Cells (LC); OCT 03-06, 2019; Mainz, GERMANY.
[Oral Communication]
Web of Science
2018
Abstract (Zeitschrift)
** Sconocchia, T; Borek, I; Schwarzenberger, E; Strobl, H
Enhanced human regulatory T cell generation by BMP7-dependent Langerhans cells via paracrine activation of the type I BMP receptor ALK3
EUR J IMMUNOL. 2018; 48: 17-18.-15th International Symposium on Dendritic Cells (DC); JUN 10-14, 2018; Aachen, GERMANY.
[Oral Communication]
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2017
Übersichtsarbeit
** Caratelli, S; Sconocchia, T; Arriga, R; Coppola, A; Lanzilli, G; Lauro, D; Venditti, A; Del Principe, MI; Buccisano, F; Maurillo, L; Ferrone, S; Sconocchia, G
FCγ Chimeric Receptor-Engineered T Cells: Methodology, Advantages, Limitations, and Clinical Relevance.
Front Immunol. 2017; 8(10):457-457
Doi: 10.3389/fimmu.2017.00457
[OPEN ACCESS]
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2016
Originalarbeit (Zeitschrift)
** Arriga, R; Caratelli, S; Coppola, A; Spagnoli, GC; Venditti, A; Amadori, S; Lanzilli, G; Lauro, D; Palomba, P; Sconocchia, T; Del Principe, MI; Maurillo, L; Buccisano, F; Capuani, B; Ferrone, S; Sconocchia, G
Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage.
Oncotarget. 2016; 7(2): 2070-2079.
Doi: 10.18632/oncotarget.6529
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