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Abdellatif Mahmoud |

** = Publications listed in SCI/SSCI/Pubmed

2025

Full paper/article (Journal)

** Abdellatif, M; Vasques-Nóvoa, F; Trummer-Herbst, V; Durand, S; Koser, F; Islam, M; Nah, J; Sung, EA; Feng, R; Aprahamian, F; Prokesch, A; Zardoya-Laguardia, P; Sadoshima, J; Diwan, A; Linke, WA; Ferreira, JP; Kroemer, G; Sedej, S Autophagy is required for the therapeutic effects of the NAD+ precursor nicotinamide in obesity-related heart failure with preserved ejection fraction.
Eur Heart J. 2025; Doi: 10.1093/eurheartj/ehaf062 [OPEN ACCESS]
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** Büttner, P; Augstein, A; Abdellatif, M; Lourenço, A; Leite-Moreira, A; Falcão-Pires, I; Werner, S; Thiele, H; Sedej, S; Schauer, A; Adams, V Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction.
ESC Heart Fail. 2025; 12(2):1474-1478 Doi: 10.1002/ehf2.15111 [OPEN ACCESS]
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** Islam, M; Rawnsley, DR; Ma, X; Navid, W; Zhao, C; Guan, X; Foroughi, L; Murphy, JT; Navid, H; Weinheimer, CJ; Kovacs, A; Nigro, J; Diwan, A; Chang, RP; Kumari, M; Young, ME; Razani, B; Margulies, KB; Abdellatif, M; Sedej, S; Javaheri, A; Covey, DF; Mani, K; Diwan, A Phosphorylation of CRYAB induces a condensatopathy to worsen post-myocardial infarction left ventricular remodeling.
J Clin Invest. 2025; 135(7): Doi: 10.1172/JCI163730 [OPEN ACCESS]
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** Paillard, M; Abdellatif, M; Andreadou, I; Bär, C; Bertrand, L; Brundel, BJJM; Chiva-Blanch, G; Davidson, SM; Dawson, D; Di, Lisa, F; Evans, P; Giricz, Z; Hausenloy, DJ; Kleinbongard, P; Lezoualc'h, F; Liehn, E; Maack, C; Maguy, A; Murphy, E; Perrino, C; Pesce, M; Rainer, PP; Streckfuss-Bömeke, K; Thielmann, M; Tian, R; Tocchetti, CG; Van, Der, Velden, J; Van, Linthout, S; Zacchigna, S; Krieg, T Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function.
Eur J Heart Fail. 2025; Doi: 10.1002/ejhf.3674
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** Ruperez, C; Madeo, F; de, Cabo, R; Kroemer, G; Abdellatif, M Obesity accelerates cardiovascular ageing.
Eur Heart J. 2025; Doi: 10.1093/eurheartj/ehaf216
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Short report/Letter

** Stockner, A; Degli, Innocenti, M; Verma, D; Schmid, S; Fuerlinger, A; Varghese, A; Zirlik, A; Schreiber, R; Breinbauer, R; Abdellatif, M; Sedej, S Inhibition of Adipose Tissue Lipolysis Treats Obesity-Related HFpEF.
Circ Res. 2025; Doi: 10.1161/CIRCRESAHA.125.326251
PubMed FullText FullText_MUG

 

Review

** Fuerlinger, A; Stockner, A; Sedej, S; Abdellatif, M Caloric restriction and its mimetics in heart failure with preserved ejection fraction: mechanisms and therapeutic potential.
Cardiovasc Diabetol. 2025; 24(1): 21 Doi: 10.1186/s12933-024-02566-8 [OPEN ACCESS]
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** Liberale, L; Tual-Chalot, S; Sedej, S; Ministrini, S; Georgiopoulos, G; Grunewald, M; Bäck, M; Bochaton-Piallat, ML; Boon, RA; Ramos, GC; de, Winther, MPJ; Drosatos, K; Evans, PC; Ferguson, JF; Forslund-Startceva, SK; Goettsch, C; Giacca, M; Haendeler, J; Kallikourdis, M; Ketelhuth, DFJ; Koenen, RR; Lacolley, P; Lutgens, E; Maffia, P; Miwa, S; Monaco, C; Montecucco, F; Norata, GD; Osto, E; Richardson, GD; Riksen, NP; Soehnlein, O; Spyridopoulos, I; Van, Linthout, S; Vilahur, G; Wentzel, JJ; Andrés, V; Badimon, L; Benetos, A; Binder, CJ; Brandes, RP; Crea, F; Furman, D; Gorbunova, V; Guzik, TJ; Hill, JA; Lüscher, TF; Mittelbrunn, M; Nencioni, A; Netea, MG; Passos, JF; Stamatelopoulos, KS; Tavernarakis, N; Ungvari, Z; Wu, JC; Kirkland, JL; Camici, GG; Dimmeler, S; Kroemer, G; Abdellatif, M; Stellos, K Roadmap for alleviating the manifestations of ageing in the cardiovascular system.
Nat Rev Cardiol. 2025; Doi: 10.1038/s41569-025-01130-5
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Editorial

** Abdellatif, M; Linke, WA; Dawson, DK, , ESC, Working, Group, on, Myocardial, Function The ESC Working Group on Myocardial Function.
Eur Heart J. 2025; Doi: 10.1093/eurheartj/ehae016
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2024

Full paper/article (Journal)

** Abdellatif, M; Schmid, ST; Fuerlinger, A; Kroemer, G Anti-ageing interventions for the treatment of cardiovascular disease.
Cardiovasc Res. 2024; Doi: 10.1093/cvr/cvae177
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** Aziz, F; Tripolt, NJ; Pferschy, PN; Scharnagl, H; Abdellatif, M; Oulhaj, A; Benedikt, M; Kolesnik, E; von, Lewinski, D; Sourij, H Ketone body levels and its associations with cardiac markers following an acute myocardial infarction: a post hoc analysis of the EMMY trial.
Cardiovasc Diabetol. 2024; 23(1): 145 Doi: 10.1186/s12933-024-02221-2 [OPEN ACCESS]
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** Cerrato, G; Liu, P; Zhao, L; Petrazzuolo, A; Humeau, J; Schmid, ST; Abdellatif, M; Sauvat, A; Kroemer, G AI-based classification of anticancer drugs reveals nucleolar condensation as a predictor of immunogenicity.
Mol Cancer. 2024; 23(1):275 Doi: 10.1186/s12943-024-02189-3 [OPEN ACCESS]
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** Hofer, SJ; Daskalaki, I; Abdellatif, M; Stelzl, U; Sedej, S; Tavernarakis, N; Kroemer, G; Madeo, F A surge in endogenous spermidine is essential for rapamycin-induced autophagy and longevity.
Autophagy. 2024; Doi: 10.1080/15548627.2024.2396793 [OPEN ACCESS]
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** Hofer, SJ; Daskalaki, I; Bergmann, M; Friščić, J; Zimmermann, A; Mueller, MI; Abdellatif, M; Nicastro, R; Masser, S; Durand, S; Nartey, A; Waltenstorfer, M; Enzenhofer, S; Faimann, I; Gschiel, V; Bajaj, T; Niemeyer, C; Gkikas, I; Pein, L; Cerrato, G; Pan, H; Liang, Y; Tadic, J; Jerkovic, A; Aprahamian, F; Robbins, CE; Nirmalathasan, N; Habisch, H; Annerer, E; Dethloff, F; Stumpe, M; Grundler, F; Wilhelmi, de, Toledo, F; Heinz, DE; Koppold, DA; Rajput, Khokhar, A; Michalsen, A; Tripolt, NJ; Sourij, H; Pieber, TR; de, Cabo, R; McCormick, MA; Magnes, C; Kepp, O; Dengjel, J; Sigrist, SJ; Gassen, NC; Sedej, S; Madl, T; De, Virgilio, C; Stelzl, U; Hoffmann, MH; Eisenberg, T; Tavernarakis, N; Kroemer, G; Madeo, F Spermidine is essential for fasting-mediated autophagy and longevity.
Nat Cell Biol. 2024; 26(9):1571-1584 Doi: 10.1038/s41556-024-01468-x [OPEN ACCESS]
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Review

** Falcão-Pires, I; Ferreira, AF; Trindade, F; Bertrand, L; Ciccarelli, M; Visco, V; Dawson, D; Hamdani, N; Van, Laake, LW; Lezoualc'h, F; Linke, WA; Lunde, IG; Rainer, PP; Abdellatif, M; Van, der, Velden, J; Cosentino, N; Paldino, A; Pompilio, G; Zacchigna, S; Heymans, S; Thum, T; Tocchetti, CG Mechanisms of myocardial reverse remodelling and its clinical significance: A scientific statement of the ESC Working Group on Myocardial Function.
Eur J Heart Fail. 2024; Doi: 10.1002/ejhf.3264
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** Madreiter-Sokolowski, CT; Hiden, U; Krstic, J; Panzitt, K; Wagner, M; Enzinger, C; Khalil, M; Abdellatif, M; Malle, E; Madl, T; Osto, E; Schosserer, M; Binder, CJ; Olschewski, A Targeting organ-specific mitochondrial dysfunction to improve biological aging.
Pharmacol Ther. 2024; 262:108710 Doi: 10.1016/j.pharmthera.2024.108710
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** Ozcan, M; Abdellatif, M; Javaheri, A; Sedej, S Risks and Benefits of Intermittent Fasting for the Aging Cardiovascular System.
Can J Cardiol. 2024; 40(8):1445-1457 Doi: 10.1016/j.cjca.2024.02.004
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** Zimmermann, A; Madeo, F; Diwan, A; Sadoshima, J; Sedej, S; Kroemer, G; Abdellatif, M Metabolic control of mitophagy.
Eur J Clin Invest. 2024; 54(4):e14138 Doi: 10.1111/eci.14138
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2023

Full paper/article (Journal)

** Messerer, J; Wrede, C; Schipke, J; Brandenberger, C; Abdellatif, M; Eisenberg, T; Madeo, F; Sedej, S; Mühlfeld, C Spermidine supplementation influences mitochondrial number and morphology in the heart of aged mice.
J Anat. 2023; 242(1):91-101 Doi: 10.1111/joa.13618 [OPEN ACCESS]
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** Montegut, L; Joseph, A; Chen, H; Abdellatif, M; Ruckenstuhl, C; Motino, O; Lambertucci, F; Anagnostopoulos, G; Lachkar, S; Dichtinger, S; Maiuri, MC; Goldwasser, F; Blanchet, B; Fumeron, F; Martins, I; Madeo, F; Kroemer, G High plasma concentrations of acyl-coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging function of ACBP
AGING CELL. 2023; 22(1): Doi: 10.1111/acel.13751 [OPEN ACCESS]
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Short report/Letter

** Abdellatif, M; Madeo, F; Sedej, S; Kroemer, G Antagonistic pleiotropy: the example of cardiac insulin-like growth factor signaling, which is essential in youth but detrimental in age.
Expert Opin Ther Targets. 2023; 27(2):87-90 Doi: 10.1080/14728222.2023.2178420 (- Case Report)
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Review

** Abdellatif, M; Rainer, PP; Sedej, S; Kroemer, G Hallmarks of cardiovascular ageing.
Nat Rev Cardiol. 2023; Doi: 10.1038/s41569-023-00881-3
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** Montegut, L; Abdellatif, M; Motino, O; Madeo, F; Martins, I; Quesada, V; Lopez-Otin, C; Kroemer, G Acyl coenzyme A binding protein (ACBP): An aging- and disease-relevant "autophagy checkpoint"
AGING CELL. 2023; Doi: 10.1111/acel.13910 [OPEN ACCESS]
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Editorial

** Abdellatif, M; Montégut, L; Kroemer, G Actionable autophagy checkpoints in cardiovascular ageing
EUR HEART J. 2023; Doi: 10.1093/eurheartj/ehad661
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** Monteuta, L; Joseph, A; Chena, H; Abdellatif, M; Ruckenstuhlg, C; Martins, I; Madeo, F; Kroemer, G DBI/ACBP is a targetable autophagy checkpoint involved in aging and cardiovascular disease
AUTOPHAGY. 2023; Doi: 10.1080/15548627.2022.2160565 [OPEN ACCESS]
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2022

Full paper/article (Journal)

** Abdellatif, M; Eisenberg, T; Heberle, AM; Thedieck, K; Kroemer, G; Sedej, S Cardiac PI3K p110 alpha attenuation delays aging and extends lifespan
CELL STRESS. 2022; 6(8): 72-75. Doi: 10.15698/cst2022.08.270 [OPEN ACCESS]
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** Abdellatif, M; Trummer-Herbst, V; Heberle, AM; Humnig, A; Pendl, T; Durand, S; Cerrato, G; Hofer, SJ; Islam, M; Voglhuber, J; Ramos, Pittol, JM; Kepp, O; Hoefler, G; Schmidt, A; Rainer, PP; Scherr, D; von, Lewinski, D; Bisping, E; McMullen, JR; Diwan, A; Eisenberg, T; Madeo, F; Thedieck, K; Kroemer, G; Sedej, S Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity.
Circulation. 2022; 145(25):1853-1866 Doi: 10.1161/CIRCULATIONAHA.122.059863 [OPEN ACCESS]
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** Herrero-Galán, E; Martínez-Martín, I; Sánchez-González, C; Vicente, N; Bonzón-Kulichenko, E; Calvo, E; Suay-Corredera, C; Pricolo, MR; Fernández-Trasancos, Á; Velázquez-Carreras, D; Careaga, CB; Abdellatif, M; Sedej, S; Rainer, PP; Giganti, D; Pérez-Jiménez, R; Vázquez, J; Alegre-Cebollada, J Basal oxidation of conserved cysteines modulates cardiac titin stiffness and dynamics.
Redox Biol. 2022; 52:102306 Doi: 10.1016/j.redox.2022.102306 [OPEN ACCESS]
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** Koser, F; Hobbach, AJ; Abdellatif, M; Herbst, V; Türk, C; Reinecke, H; Krüger, M; Sedej, S; Linke, WA Acetylation and phosphorylation changes to cardiac proteins in experimental HFpEF due to metabolic risk reveal targets for treatment.
Life Sci. 2022; 309:120998 Doi: 10.1016/j.lfs.2022.120998
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** Ljubojević-Holzer, S; Kraler, S; Djalinac, N; Abdellatif, M; Voglhuber, J; Schipke, J; Schmidt, M; Kling, KM; Franke, GT; Herbst, V; Zirlik, A; von, Lewinski, D; Scherr, D; Rainer, PP; Kohlhaas, M; Nickel, A; Mühlfeld, C; Maack, C; Sedej, S Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling.
Cardiovasc Res. 2022; 118(6):1492-1505 Doi: 10.1093/cvr/cvab112 [OPEN ACCESS]
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** Rech, L; Abdellatif, M; Pöttler, M; Stangl, V; Mabotuwana, N; Hardy, S; Rainer, PP Small molecule STING inhibition improves myocardial infarction remodeling.
Life Sci. 2022; 291:120263 Doi: 10.1016/j.lfs.2021.120263
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** Ring, J; Tadic, J; Ristic, S; Poglitsch, M; Bergmann, M; Radic, N; Mossmann, D; Liang, YT; Maglione, M; Jerkovic, A; Hajiraissi, R; Hanke, M; Kuttner, V; Wolinski, H; Zimmermann, A; Trifunovic, LD; Mikolasch, L; Moretti, DN; Broeskamp, F; Westermayer, J; Abraham, C; Schauer, S; Dammbrueck, C; Hofer, SJ; Abdellatif, M; Grundmeier, G; Kroemer, G; Braun, RJ; Hansen, N; Sommer, C; Ninkovic, M; Seba, S; Rockenfeller, P; Vogtle, FN; Dengjel, J; Meisinger, C; Keller, A; Sigrist, SJ; Eisenberg, T; Madeo, F The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity
EMBO MOL MED. 2022; e13952 Doi: 10.15252/emmm.202113952 [OPEN ACCESS]
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Short report/Letter

** Abdellatif, M; Kroemer, G Heart failure with preserved ejection fraction: An age-related condition
J MOL CELL CARDIOL. 2022; 167: 83-84. Doi: 10.1016/j.yjmcc.2022.03.008
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Review

** Abdellatif, M; Bugger, H; Kroemer, G; Sedej, S NAD+ and Vascular Dysfunction: From Mechanisms to Therapeutic Opportunities.
J Lipid Atheroscler. 2022; 11(2): 111-132. Doi: 10.12997/jla.2022.11.2.111 [OPEN ACCESS]
PubMed PUBMED Central FullText FullText_MUG

 

Editorial

** Sedej, S; Abdellatif, M Metabolic therapy for managing heart failure with preserved ejection fraction.
J Mol Cell Cardiol. 2022; 168:68-69 Doi: 10.1016/j.yjmcc.2022.04.009
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Abstract (Journal)

** Abdellatif, M; Trummer-Herbst, V; Koser, F; Linke, W; Sadoshima, J; Diwan, A; Kroemer, G; Sedej, S Autophagy causally contributes to the cardioprotective effects of NAD
WIEN KLIN WOCHENSCHR. 2022; 134(SUPPL 2):82-82.-ÖKG Jahrestagung; 25-28 May; Salzburg, Austria. [Oral Communication]
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** Abdellatif, M; Trummer-Herbst, V; Prokesch, A; Zardoya-Laguardia, P; Linke, WA; Sadoshima, J; Diwan, A; Kroemer, G; Sedej, S Autophagy is required for NAD-based HFpEF therapy
EUR J HEART FAIL. 2022; 24: 9-9.-HFA Winter Meeting on Translational Heart Failure Research; JAN 27-28, 2022; Switzerland. [Oral Communication]
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** Koser, F; Abdellatif, M; Tuerk, C; Hobbach, AJ; Reinecke, H; Krueger, M; Sedej, S; Linke, WA Cardiac proteomic analyses in a rat model of heart failure with preserved ejection fraction (HFpEF) reveals key pathway modifications due to obesity
ACTA PHYSIOL. 2022; 236: 597-597. [Oral Communication]
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** Koser, F; Abdellatif, M; Turk, C; Hobbach, AJ; Reinecke, H; Kruger, M; Sedej, S; Linke, W Proteomic screening in a rat model of HFpEF reveals key pathway modifications due to obesity
J MOL CELL CARDIOL. 2022; 173: S16-S17. Doi: 10.1016/j.yjmcc.2022.08.034
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Comment

** Abdellatif, M; Madeo, F; Kroemer, G; Sedej, S Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart.
Autophagy. 2022; 18(10): 2500-2502. Doi: 10.1080/15548627.2022.2095835 [OPEN ACCESS]
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** Sedej, S; Abdellatif, M Response by Sedej and Abdellatif to Letter Regarding Article, "Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity".
Circulation. 2022; 146(24): e332-e333. Doi: 10.1161/CIRCULATIONAHA.122.062496
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2021

Full paper/article (Journal)

** Abdellatif, M; Kroemer, G Exercise-induced sudden cardiac death is caused by mitochondrio-nuclear translocation of AIF.
Cell Death Dis. 2021; 12(4):383-383 Doi: 10.1038/s41419-021-03677-w [OPEN ACCESS]
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** Abdellatif, M; Trummer-Herbst, V; Koser, F; Durand, S; Adão, R; Vasques-Nóvoa, F; Freundt, JK; Voglhuber, J; Pricolo, MR; Kasa, M; Türk, C; Aprahamian, F; Herrero-Galán, E; Hofer, SJ; Pendl, T; Rech, L; Kargl, J; Anto-Michel, N; Ljubojevic-Holzer, S; Schipke, J; Brandenberger, C; Auer, M; Schreiber, R; Koyani, CN; Heinemann, A; Zirlik, A; Schmidt, A; von Lewinski, D; Scherr, D; Rainer, PP; von Maltzahn, J; Mühlfeld, C; Krüger, M; Frank, S; Madeo, F; Eisenberg, T; Prokesch, A; Leite-Moreira, AF; Lourenço, AP; Alegre-Cebollada, J; Kiechl, S; Linke, WA; Kroemer, G; Sedej, S Nicotinamide for the treatment of heart failure with preserved ejection fraction.
Sci Transl Med. 2021; 13(580): eabd7064 Doi: 10.1126/scitranslmed.abd7064 [OPEN ACCESS]
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** Klionsky, DJ; Abdel-Aziz, AK; Abdelfatah, S; Abdellatif, M; Abdoli, A; Abel, S; Abeliovich, H; Abildgaard, MH; Abudu, YP; Acevedo-Arozena, A; Adamopoulos, IE; Adeli, K; Adolph, TE; Adornetto, A; Aflaki, E; Agam, G; Agarwal, A; Aggarwal, BB; Agnello, M; Agostinis, P; Agrewala, JN; Agrotis, A; Aguilar, PV; Ahmad, ST; Ahmed, ZM; Ahumada-Castro, U; Aits, S; Aizawa, S; Akkoc, Y; Akoumianaki, T; Akpinar, HA; Al-Abd, AM; Al-Akra, L; Al-Gharaibeh, A; Alaoui-Jamali, MA; Alberti, S; Alcocer-Gómez, E; Alessandri, C; Ali, M; Alim, Al-Bari, MA; Aliwaini, S; Alizadeh, J; Almacellas, E; Almasan, A; Alonso, A; Alonso, GD; Altan-Bonnet, N; Altieri, DC; Álvarez, ÉMC; Alves, S; Alves, da, Costa, C; Alzaharna, MM; Amadio, M; Amantini, C; Amaral, C; Ambrosio, S; Amer, AO; Ammanathan, V; An, Z; Andersen, SU; Andrabi, SA; Andrade-Silva, M; Andres, AM; Angelini, S; et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
AUTOPHAGY. 2021; 17(1): 1-382. Doi: 10.1080/15548627.2020.1797280 [OPEN ACCESS]
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Review

** Abdellatif, M; Sedej, S; Kroemer, G NAD+ Metabolism in Cardiac Health, Aging, and Disease.
Circulation. 2021; 144(22): 1795-1817. Doi: 10.1161/CIRCULATIONAHA.121.056589
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** Voglhuber, J; Ljubojevic-Holzer, S; Abdellatif, M; Sedej, S Targeting Cardiovascular Risk Factors Through Dietary Adaptations and Caloric Restriction Mimetics.
Front Nutr. 2021; 8: 758058 Doi: 10.3389/fnut.2021.758058 [OPEN ACCESS]
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** Zimmermann, A; Madreiter-Sokolowski, C; Stryeck, S; Abdellatif, M Targeting the Mitochondria-Proteostasis Axis to Delay Aging.
FRONT CELL DEV BIOL. 2021; 9(3): 656201-656201. Doi: 10.3389/fcell.2021.656201 [OPEN ACCESS]
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Editorial

** Abdellatif, M; Baur, JA NAD(+) metabolism and cardiometabolic health: the human evidence
CARDIOVASC RES. 2021; 117(9): E106-E109. Doi: 10.1093/cvr/cvab212 [OPEN ACCESS]
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** Abdellatif, M; Lam, CSP Scientists on the Spot: A fraction of wisdom on heart failure
CARDIOVASC RES. 2021; 117(9): E114-E115. Doi: 10.1093/cvr/cvab230
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Abstract (Journal)

** Abdellatif, M; Trummer-Herbst, V; Koser, F; Durand, S; Adao, R; Von Lewinski, D; Rainer, P; Scherr, D; Zirlik, A; Leite-Moreira, A; Alegre-Cebollada, J; Kiechl, S; Linke, W; Kroemer, G; Sedej, S Boosting NAD+ metabolism improves diastolic dysfunction in animal models of aging, obesity and hypertension
WIEN KLIN WOCHENSCHR. 2021; 133(SUPPL 3):S53-S54. [Oral Communication]
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** Abdellatif, M; Trummer-Herbst, V; Koser, F; Sylvere, D; Adao, R; Vasques-Novoa, F; Freundt, JK; Von Lewinski, D; Leite-Moreira, AF; Lourenco, AP; Alegre-Cebollada, J; Kiechl, S; Linke, WA; Kroemer, G; Sedej, S Nicotinamide treats cardiac hallmarks of experimental heart failure with preserved ejection fraction
EUR J HEART FAIL. 2021; 23: 4-4.-HF Winter Meeting; JAN 20-21, 2021; Sophia Antipolis, France. [Oral Communication]
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** Abdellatif, M; Trummer-Herbst, V; Pendl, T; Hofer, S; Durand, S; Voglhuber, J; Von Lewinski, D; Rainer, P; Scherr, D; Zirlik, A; Eisenberg, T; Kroemer, G; Madeo, F; Bisping, E; Sedej, S Targeting IGF1 Signalling to Promote Cardiac Health and Longevity
WIEN KLIN WOCHENSCHR. 2021; 133(SUPPL 3):S35-S35. [Oral Communication]
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** Rech, L; Abdellatif, M; Poettler, M; Stangl, V; Ulcar, E; Ablasser, A; Rainer, PP STING inhibition in myocardial remodelling following myocardial infarction
EUR HEART J. 2021; 42: 3242-3242. [Poster]
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** Rech, L; Abdellatif, M; Pottler, M; Stangl, V; Ulcar, E; Gulen, M; Ablasser, A; Rainer, PP STING-Inhibition after myocardial infarction
WIEN KLIN WOCHENSCHR. 2021; 133(SUPPL 3): S57-S57. [Poster]
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** Voglhuber, J; Abdellatif, M; Djalinac, N; Trummer-Herbst, V; Ljubojevic-Holzer, S; Sedej, S Altered spatio-specific CaMKII activation in autophagy deficient mice
EUR HEART J. ESC Congress 2021 Abstract Supplement. 2021; 42(S1):3284-3284.-ESC Congress 2021 - The Digital Experience; AUG 27 - 30, 2021; Virtuell. [Onlinepräsentation]
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** Voglhuber, J; Abdellatif, M; Djalinac, N; Trummer-Herbst, V; Ljubojevic-Holzer, S; Sedej, S Altered spatio-specific CaMKII activation in autophagy deficient mice
WIEN KLIN WOCHENSCHR. 2021; 133(SUPPL 3):S35-S35.-Jahrestagung der ÖKG 2021; MAY 27-29, 2021; Salzburg, AUSTRIA - online. [Onlinepräsentation]
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Comment

** Abdellatif, M; Kroemer, G Co-ordinated mitochondrial degradation by autophagy and heterophagy in cardiac homeostasis.
Cardiovasc Res. 2021; 117(1):e1-e3-e1-e3 Doi: 10.1093/cvr/cvaa345 [OPEN ACCESS]
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2020

Full paper/article (Journal)

** Abdellatif, M; Ljubojevic-Holzer, S; Madeo, F; Sedej, S Autophagy in cardiovascular health and disease.
Prog Mol Biol Transl Sci. 2020; 172:87-106 Doi: 10.1016/bs.pmbts.2020.04.022
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** Ljubojevic-Holzer, S; Herren, AW; Djalinac, N; Voglhuber, J; Morotti, S; Holzer, M; Wood, BM; Abdellatif, M; Matzer, I; Sacherer, M; Radulovic, S; Wallner, M; Ivanov, M; Wagner, S; Sossalla, S; von Lewinski, D; Pieske, B; Brown, JH; Sedej, S; Bossuyt, J; Bers, DM CaMKIIδC Drives Early Adaptive Ca2+ Change and Late Eccentric Cardiac Hypertrophy.
Circ Res. 2020; 127(9):1159-1178 Doi: 10.1161/CIRCRESAHA.120.316947 [OPEN ACCESS]
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Correspondence

** Abdellatif, M; Sedej, S Cardiovascular benefits of intermittent fasting.
Cardiovasc Res. 2020; 116(3): e36-e38-e36-e38. Doi: 10.1093/cvr/cvaa022 [OPEN ACCESS]
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Abstract (Journal)

** Eaton, D; Kasa, M; Abdellatif, M; Ljubojevic-Holzer, S; Zugner, E; Magnes, C; Sourij, H; von Lewinski, D; Rainer, P; Angleitner, P; Zuckermann, A; Aliabadi-Zuckermann, A; Zirlik, A; Pieber, T; Houser, SR; Wallner, M Metabolic effects of HDAC inhibition in a feline model of HFpEF.
WIEN KLIN WOCHENSCHR. 2020; 132: S163-S164. [Poster]
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Biographical-Item

** Abdellatif, M; Vilahur, G Scientists on the Spot: from the Scientists of Tomorrow to the scientist of today.
Cardiovasc Res. 2020; 116(13):e184-e185-e184-e185 Doi: 10.1093/cvr/cvaa277 [OPEN ACCESS]
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Comment

** Abdellatif, M; Zirlik, A Immunometabolism: a key target to improve microcirculation in ageing.
Cardiovasc Res. 2020; 116(5):e48-e50-e48-e50 Doi: 10.1093/cvr/cvaa060 [OPEN ACCESS]
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2019

Full paper/article (Journal)

** Carmona-Gutierrez, D; Zimmermann, A; Kainz, K; Pietrocola, F; Chen, G; Maglioni, S; Schiavi, A; Nah, J; Mertel, S; Beuschel, CB; Castoldi, F; Sica, V; Trausinger, G; Raml, R; Sommer, C; Schroeder, S; Hofer, SJ; Bauer, MA; Pendl, T; Tadic, J; Dammbrueck, C; Hu, Z; Ruckenstuhl, C; Eisenberg, T; Durand, S; Bossut, N; Aprahamian, F; Abdellatif, M; Sedej, S; Enot, DP; Wolinski, H; Dengjel, J; Kepp, O; Magnes, C; Sinner, F; Pieber, TR; Sadoshima, J; Ventura, N; Sigrist, SJ; Kroemer, G; Madeo, F The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species.
Nat Commun. 2019; 10(1):651-651 Doi: 10.1038/s41467-019-08555-w [OPEN ACCESS]
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** Hofer, DC; Zirkovits, G; Pelzmann, HJ; Huber, K; Pessentheiner, AR; Xia, W; Uno, K; Miyazaki, T; Kon, K; Tsuneki, H; Pendl, T; Al Zoughbi, W; Madreiter-Sokolowski, CT; Trausinger, G; Abdellatif, M; Schoiswohl, G; Schreiber, R; Eisenberg, T; Magnes, C; Sedej, S; Eckhardt, M; Sasahara, M; Sasaoka, T; Nitta, A; Hoefler, G; Graier, WF; Kratky, D; Auwerx, J; Bogner-Strauss, JG N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health.
FASEB J. 2019; 33(12):13808-13824 Doi: 10.1096/fj.201801323R [OPEN ACCESS]
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** Wierich, MC; Schipke, J; Brandenberger, C; Abdellatif, M; Eisenberg, T; Madeo, F; Sedej, S; Mühlfeld, C Cardioprotection by spermidine does not depend on structural characteristics of the myocardial microcirculation in aged mice.
Exp Gerontol. 2019; 119:82-88 Doi: 10.1016/j.exger.2019.01.026
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Correction

** Wierich, MC; Schipke, J; Brandenberger, C; Abdellatif, M; Eisenberg, T; Madeo, F; Sedej, S; Muhlfeld, C Cardioprotection by spermidine does not depend on structural characteristics of the myocardial microcirculation in aged mice (vol 199, pg 82, 2019)
EXP GERONTOL. 2019; 122: 139-139. Doi: 10.1016/j.exger.2019.05.009
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Abstract (Journal)

** Abdellatif, M; Herbst, V; Schmidt, A; Humnig, A; Pendl, T; Gross, A; Hofer, S; Madeo, F; Zirlik, A; Scherr, D; von Lewinski, D; Rainer, P; McMullen, J; Eisenberg, T; Bisping, E; Sedej, S Life stage determines the dual effects of IGF1 signalling on cardiac health and survival
WIEN KLIN WOCHENSCHR. 2019; 131: 250-250. [Oral Communication]
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** Koser, F; Abdellatif, M; Turk, C; Kruger, M; Sedej, S; Linke, WA Unbiased screen of the cardiac proteome and effect of spermidine therapy on titin properties in a rat model of heart failure with preserved ejection fraction (HFpEF)
ACTA PHYSIOL. 2019; 227: -98th Meeting of the German Physiological Society ; SEP 30-OCT 02, 2019; Ulm, Germany. [Poster]
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Comment

** Abdellatif, M Autophagy promotes longevity-except in the presence of 'leaky' mitochondria.
Cardiovasc Res. 2019; 115(12):e118-e120-e118-e120 Doi: 10.1093/cvr/cvz224 [OPEN ACCESS]
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Meeting Report

** Abdellatif, M; Patel, J; Smits, AM Highlights of ESC Congress 2019: a report from the ESC Scientists of Tomorrow.
Cardiovasc Res. 2019; 115(13):e151-e154-e151-e154 Doi: 10.1093/cvr/cvz266 [OPEN ACCESS]
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2018

Review

** Abdellatif, M; Sedej, S; Carmona-Gutierrez, D; Madeo, F; Kroemer, G Autophagy in Cardiovascular Aging.
Circ Res. 2018; 123(7):803-824 Doi: 10.1161/CIRCRESAHA.118.312208 [OPEN ACCESS]
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Abstract (Journal)

** Kolesnik, E; Kapeller, S; Wallner, M; Rainer, PP;, Abdellatif, M; Maechler, H; Sedej, S; Von Lewinski D Acute administration of high levels of spermidine and spermine impair ryanodine receptor type 2-dependent contractility in human atrial tissue
European Journal of Heart Failure. 2018; 20(S1):630-630.-ESC Heart Failure 2018; MAY 26-29, 2018; Vienna, Austria. [Poster]
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** Kraler, S; Abdellatif, M; Ljubojevic, S; Sedej, SS Beta-adrenergic effect on calcium cycling is potentiated in autophagy-deficient mouse cardiomyocytes
EUR J HEART FAIL. 2018; 20: 620-621. [Poster]
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** Kraler, S; Abdellatif, M; Schipke, J; Kling, KM; Muhlfeld, C; Ljubojevic, S; Sedej, S Potentiated effect of isoprenaline on calcium homeostasis in mouse cardiomyocytes with inhibited autophagy
WIEN KLIN WOCHENSCHR. 2018; 130: 12-14.-Jahrestagung der Österreichischen Kardiologischen Gesellschaft; Jun 6-9, 2018 ; Salzburg, Austria. [Poster]
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Comment

** Abdellatif, M; Sedej, S; Madeo, F; Kroemer, G Cardioprotective effects of autophagy induction in sepsis.
Ann Transl Med. 2018; 6(Suppl 1):S61-S61 Doi: 10.21037/atm.2018.10.23 [OPEN ACCESS]
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2017

Full paper/article (Journal)

** Eisenberg, T; Abdellatif, M; Zimmermann, A; Schroeder, S; Pendl, T; Harger, A; Stekovic, S; Schipke, J; Magnes, C; Schmidt, A; Ruckenstuhl, C; Dammbrueck, C; Gross, AS; Herbst, V; Carmona-Gutierrez, D; Pietrocola, F; Pieber, TR; Sigrist, SJ; Linke, WA; Mühlfeld, C; Sadoshima, J; Dengjel, J; Kiechl, S; Kroemer, G; Sedej, S; Madeo, F Dietary spermidine for lowering high blood pressure.
Autophagy. 2017; 13(4):767-769 Doi: 10.1080/15548627.2017.1280225 [OPEN ACCESS]
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** Schreiber, R; Diwoky, C; Schoiswohl, G; Feiler, U; Wongsiriroj, N; Abdellatif, M; Kolb, D; Hoeks, J; Kershaw, EE; Sedej, S; Schrauwen, P; Haemmerle, G; Zechner, R Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue.
Cell Metab. 2017; 26(5):753-763 Doi: 10.1016/j.cmet.2017.09.004 [OPEN ACCESS]
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Abstract (Journal)

** Abdellatif, M; Eisenberg, T; Schmidt, A; Linke, W A; Muehlfeld, C; JSadoshima, J; Kiechl, S; Kroemer, G; Madeo, F; Sedej, S The natural autophagy-inducer spermidine protects the aging heart and promotes longevity in mice
European Journal of Heart Failure. 2017; 19(S1):514-515.-Heart Failure 2017 and the 4th World Congress on Acute Heart Failure; April 29- May 2, 2017; Paris, France. [Poster]
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** Sedei, S; Abdellatif, M; Eisenberg, T; Primessnig, U; Pendl, T; von Frieling-Salewsky, M; Magnes, C; Herbst, V; Kirsch, A; Meinitzer, A; Linke, WA; Kiechl, S; Kroemer, G; Madeo, F Spermidine feeding reduces high blood pressure and improves diastolic function in Dahl salt-sensitive rats
ACTA PHYSIOL. 2017; 221: 34-34. [Oral Communication]
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2016

Full paper/article (Journal)

** Abdellatif, M; Leite, S; Alaa, M; Oliveira-Pinto, J; Tavares-Silva, M; Fontoura, D; Falcão-Pires, I; Leite-Moreira, AF; Lourenço, AP Spectral transfer function analysis of respiratory hemodynamic fluctuations predicts end-diastolic stiffness in preserved ejection fraction heart failure.
Am J Physiol Heart Circ Physiol. 2016; 310(1):H4-13 Doi: 10.1152/ajpheart.00399.2015 [OPEN ACCESS]
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** Alaa, M; Abdellatif, M; Tavares-Silva, M; Oliveira-Pinto, J; Lopes, L; Leite, S; Leite-Moreira, AF; Lourenço, AP Right ventricular end-diastolic stiffness heralds right ventricular failure in monocrotaline-induced pulmonary hypertension.
Am J Physiol Heart Circ Physiol. 2016; 311(4):H1004-H1013 Doi: 10.1152/ajpheart.00202.2016 [OPEN ACCESS]
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** Eisenberg, T; Abdellatif, M; Schroeder, S; Primessnig, U; Stekovic, S; Pendl, T; Harger, A; Schipke, J; Zimmermann, A; Schmidt, A; Tong, M; Ruckenstuhl, C; Dammbrueck, C; Gross, AS; Herbst, V; Magnes, C; Trausinger, G; Narath, S; Meinitzer, A; Hu, Z; Kirsch, A; Eller, K; Carmona-Gutierrez, D; Büttner, S; Pietrocola, F; Knittelfelder, O; Schrepfer, E; Rockenfeller, P; Simonini, C; Rahn, A; Horsch, M; Moreth, K; Beckers, J; Fuchs, H; Gailus-Durner, V; Neff, F; Janik, D; Rathkolb, B; Rozman, J; de Angelis, MH; Moustafa, T; Haemmerle, G; Mayr, M; Willeit, P; von Frieling-Salewsky, M; Pieske, B; Scorrano, L; Pieber, T; Pechlaner, R; Willeit, J; Sigrist, SJ; Linke, WA; Mühlfeld, C; Sadoshima, J; Dengjel, J; Kiechl, S; Kroemer, G; Sedej, S; Madeo, F Cardioprotection and lifespan extension by the natural polyamine spermidine.
Nat Med. 2016; 22(12):1428-1438 Doi: 10.1038/nm.4222 [OPEN ACCESS]
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Abstract (Journal)

** Alaa, M; Abdellatif, M; Leite-Moreira, AF; Lourenco, AP Pulmonary hypertension induced right ventricular stiffness predicted by spectral transfer function analysis: an experimental study
EUR J HEART FAIL. 2016; 18: 150-150. [Poster]
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** Alaa, M; Abdellatif, M; Leite-Moreira, AF; Lourenco, AP Spectral transfer function analysis of respiratory fluctuations predicts right ventricular stiffness in experimental pulmonary hypertension
EUR HEART J. .. 2016; 37: 1363-1363.-Congress of the European-Society-of-Cardiology (ESC); AUG 27-31, 2016; Rome, ITALY. [Poster]
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** Schneider, C; Wallner, M; Abdellatif, M; von Lewinski, D; Pichler, M; Sedej, S; Rainer, P The anti-cancer tyrosine kinase inhibitor sorafenib reduces cardiac contractile force by reducing cardiomyocyte calcium transient amplitude
WIEN KLIN WOCHENSCHR. 2016; 128: S309-S310. [Poster]
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2015

Full paper/article (Journal)

** Leite, S; Oliveira-Pinto, J; Tavares-Silva, M; Abdellatif, M; Fontoura, D; Falcão-Pires, I; Leite-Moreira, AF; Lourenço, AP Echocardiography and invasive hemodynamics during stress testing for diagnosis of heart failure with preserved ejection fraction: an experimental study.
Am J Physiol Heart Circ Physiol. 2015; 308(12): H1556-H1563. Doi: 10.1152/ajpheart.00076.2015 [OPEN ACCESS]
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** Leite, S; Rodrigues, S; Tavares-Silva, M; Oliveira-Pinto, J; Alaa, M; Abdellatif, M; Fontoura, D; Falcão-Pires, I; Gillebert, TC; Leite-Moreira, AF; Lourenço, AP Afterload-induced diastolic dysfunction contributes to high filling pressures in experimental heart failure with preserved ejection fraction.
Am J Physiol Heart Circ Physiol. 2015; 309(10):H1648-H1654 Doi: 10.1152/ajpheart.00397.2015 [OPEN ACCESS]
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Abstract (Journal)

** Abdellatif, M; Alaa, M; Leite, S; Oliveira-Pinto, J; Leite-Moreira, AF; Lourenço AP Impairment of preload reserve in experimental heart failure with preserved ejection fraction: can spectral analysis contribute to diagnosis?
European Journal of Heart Failure Abstracts Supplement (2015) 17 (Supplement 1), 303. 2015; 17(S1):303-303.-Heart Failure 2015 | 2nd World Congress on Acute Heart Failure; MAY 23-26, 2015; Sevilla, SPAIN. [Poster]
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** Leite, S; Oliveira-Pinto, J; Tavares-Silva, M; Abdellatif, M; Fontoura, D; Falcão-Pires, I; Leite-Moreira, AF; Lourenço, AP Echocardiography and invasive haemodynamics during stress testing for diagnosis of heart failure with preserved ejection fraction: an experimental study
European Journal of Heart Failure Abstracts Supplement. 2015; 17(S1):240-240.-Heart Failure 2015 | 2nd World Congress on Acute Heart Failure; MAY 23-26, 2015; Seville, SPAIN. [Poster]
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