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Nussbaumer Gunther |
** = Publications listed in SCI/SSCI/Pubmed
2025
Full paper/article (Journal)
** Friker, LL; Perwein, T; Waha, A; Dörner, E; Klein, R; Blattner-Johnson, M; Layer, JP; Sturm, D; Nussbaumer, G; Kwiecien, R; Spier, I; Aretz, S; Kerl, K; Hennewig, U; Rohde, M; Karow, A; Bluemcke, I; Schmitz, AK; Reinhard, H; Driever, PH; Wendt, S; Weiser, A; Stücklin, ASG; Gerber, NU; von Bueren, AO; Khurana, C; Jorch, N; Wiese, M; Kratz, CP; Eyrich, M; Karremann, M; Herrlinger, U; Hölzel, M; Jones, DTW; Hoffmann, M; Pietsch, T; Gielen, GH; Kramm, CM
MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening method for DNA mismatch repair deficiency syndromes in pediatric high-grade glioma
ACTA NEUROPATHOL. 2025; 149(1): 11
Doi: 10.1007/s00401-025-02846-x
[OPEN ACCESS]
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PubMed
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2024
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** Baugh, JN; van Zanten, SV; Fiocco, M; Colditz, N; Hoffmann, M; Janssens, GO; Valentini, C; Hargrave, D; Wiese, M; von Bueren, AO; Karremann, M; Perwein, T; Nussbaumer, G; Benesch, M; Sturm, D; Gielen, GH; Krause, M; Eyrich, M; Hoving, EW; Bison, B; van Vuurden, DG; Kramm, CM
Treatment-related survival patterns in diffuse intrinsic pontine glioma using a historical cohort: A report from the European Society for Pediatric Oncology DIPG/DMG Registry
NEURO-ONCOL ADV. 2024; 6(1): vdae155
Doi: 10.1093/noajnl/vdae155
[OPEN ACCESS]
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** Nussbaumer, G; Benesch, M; Grabovska, Y; Mackay, A; Castel, D; Grill, J; Alonso, MM; Antonelli, M; Bailey, S; Baugh, JN; Biassoni, V; Blattner, Johnson, M; Broniscer, A; Carai, A; Colafati, GS; Colditz, N; Corbacioglu, S; Crampsie, S; Entz-Werle, N; Eyrich, M; Friker, LL; Frühwald, MC; Garrè, ML; Gerber, NU; Giangaspero, F; Gil-da-Costa, MJ; Graf, N; Hargrave, D; Hauser, P; Herrlinger, U; Hoffmann, M; Hulleman, E; Izquierdo, E; Jacobs, S; Karremann, M; Kattamis, A; Kebudi, R; Kortmann, RD; Kwiecien, R; Massimino, M; Mastronuzzi, A; Miele, E; Morana, G; Noack, CM; Pentikainen, V; Perwein, T; Pfister, SM; Pietsch, T; Roka, K; Rossi, S; Rutkowski, S; Schiavello, E; Seidel, C; Štěrba, J; Sturm, D; Sumerauer, D; Tacke, A; Temelso, S; Valentini, C; van, Vuurden, D; Varlet, P; Veldhuijzen, van, Zanten, SEM; Vinci, M; von, Bueren, AO; Warmuth-Metz, M; Wesseling, P; Wiese, M; Wolff, JEA; Zamecnik, J; Morales, La, Madrid, A; Bison, B; Gielen, GH; Jones, DTW; Jones, C; Kramm, CM
Gliomatosis cerebri in children: A poor prognostic phenotype of diffuse gliomas with a distinct molecular profile.
Neuro Oncol. 2024;
Doi: 10.1093/neuonc/noae080
[OPEN ACCESS]
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** Obrecht-Sturm, D; Schömig, L; Mynarek, M; Bison, B; Schwarz, R; Pietsch, T; Pfister, SM; Sill, M; Sturm, D; Sahm, F; Kortmann, RD; Gerber, NU; von Bueren, AO; Fleischhack, G; Schüller, U; Nussbaumer, G; Benesch, M; Rutkowski, S
Treatment response as surrogate to predict risk for disease progression in pediatric medulloblastoma with persistent magnetic resonance imaging lesions after first-line treatment
NEURO-ONCOLOGY. 2024;
Doi: 10.1093/neuonc/noae071
[OPEN ACCESS]
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** Tauziède-Espariat, A; Friker, LL; Nussbaumer, G; Bison, B; Dangouloff-Ros, V; Métais, A; Sumerauer, D; Zamecnik, J; Benesch, M; Perwein, T; van, Vuurden, D; Wesseling, P; La, Madrid, AM; Garrè, ML; Antonelli, M; Giangaspero, F; Pietsch, T; Sturm, D; Jones, DTW; Pfister, SM; Grabovska, Y; Mackay, A; Jones, C; Grill, J; Ajlil, Y; von, Bueren, AO; Karremann, M; Hoffmann, M; Kramm, CM; Kwiecien, R; Castel, D; Gielen, GH; Varlet, P
Diffuse pediatric high-grade glioma of methylation-based RTK2A and RTK2B subclasses present distinct radiological and histomolecular features including Gliomatosis cerebri phenotype.
Acta Neuropathol Commun. 2024; 12(1): 176
Doi: 10.1186/s40478-024-01881-1
[OPEN ACCESS]
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** Wiese, M; Pohlmeier, B; Kubiak, K; El-Khouly, FE; Sitte, M; Carcaboso, AM; Baugh, JN; Perwein, T; Nussbaumer, G; Karremann, M; Gielen, GH; Salinas, G; Kramm, CM
Boswellic acid formulations are not suitable for treatment of pediatric high-grade glioma due to tumor promoting potential.
J Tradit Complement Med. 2024; 14(1): 101-108.
Doi: 10.1016/j.jtcme.2023.07.007
[OPEN ACCESS]
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Abstract (Journal)
** Chavaz, L; Bagchi, A; Toutain, F; Pfister, SM; Sturm, D; Pietsch, T; Gielen, GH; Waha, A; Clarke, M; Karremann, M; Benesch, M; Perwein, T; Nussbaumer, G; Kramm, C; Massimino, M; Biassoni, V; Vinci, M; Mastronuzzi, A; van Vuurden, D; van Zanten, SEMV; Mackay, A; Jones, C; Jones, DTW; Stucklin, ASG; Tabori, U; Hawkins, C; Ryall, S; La Madrid, AM; Lassaletta, A; Bailey, S; Hargrave, D; Chiang, JS; El-Ayadi, M; Mancano, BM; Reis, RM; Hagel, C; Robinson, GW; Gajjar, A; Gorsi, H; Silvestrini, N; von Bueren, AO
INFANT-TYPE HEMISPHERIC GLIOMA (IHG): AN INDIVIDUAL PATIENT DATA META-ANALYSIS
NEURO-ONCOLOGY. 2024; 26: noae064297--International Symposium on Pediatric Neuro-Oncology (ISPNO); JUN 29-JUL 02, 2024; Philadelphia, PA.
Doi: 10.1093/neuonc/noae064.297
[Oral Communication]
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** Friker, LL; Perwein, T; Waha, A; Dörner, E; Klein, R; Blattner-Johnson, M; Layer, JP; Sturm, D; Nussbaumer, G; Kerl, K; Hennewig, U; Rohde, M; Karow, A; Bluemcke, I; Schmitz, AK; Reinhard, H; Herz, NA; Driever, PH; Wendt, S; Weiser, A; Stuecklin, ASG; Gerber, NU; von Bueren, AO; Khurana, C; Jorch, N; Kratz, CP; Eyrich, M; Karremann, M; Hölzel, M; Jones, DTW; Pietsch, T; Gielen, GH; Kramm, CM
IMMUNOHISTOCHEMISTRY REPRESENTS A HIGHLY SENSITIVE SCREENING METHOD FOR MISMATCH REPAIR DEFICIENCY SYNDROMES IN PEDIATRIC HIGH-GRADE GLIOMA
NEURO-ONCOLOGY. 2024; 26: NOAE064310--International Symposium on Pediatric Neuro-Oncology (ISPNO); JUN 29-JUL 02, 2024; Philadelphia, PA.
Doi: 10.1093/neuonc/noae064.310
[Oral Communication]
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** Perwein, T; Gielen, GH; Karremann, M; Bison, B; Damen-Korbijn, CM; Baugh, JN; Hummel, TR; Blank, C; Biassoni, V; Bellón, MC; Szychot, E; Papusha, L; Jones, DTW; Sturm, D; Hoffmann, M; Kullmann, S; Steffen, LS; Simon, T; Friker, LL; Pietsch, T; Seidel, C; Eyrich, M; El-Ayadi, M; Nussbaumer, G; Massimino, M; La Madrid, AM; Bailey, S; von Bueren, AO; Benesch, M; van Zanten, SEMV; Hoffman, L; Kramm, CM
INITIAL AND EARLY METASTATIC SPREAD IN DIPG AND DIFFUSE MIDLINE GLIOMA, H3 K27-ALTERED - REPORT FROM THE EUROPEAN SOCIETY FOR PEDIATRIC ONCOLOGY (SIOPE) AND INTERNATIONAL DIPG/DMG REGISTRIES
NEURO-ONCOLOGY. 2024; 26: -International Symposium on Pediatric Neuro-Oncology (ISPNO); JUN 29-JUL 02, 2024; Philadelphia, PA.
Doi: 10.1093/neuonc/noae064.110
[Keynote lecture]
Web of Science
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** Perwein, T; Nussbaumer, G; Filipek, I; Piccolo, G; Garrè, ML; Castellano, S; Lassaletta, A; Salvador, H; Baroni, L; Valera, ET; Scrideli, C; Jónsson, OG; Scheinemann, K; Kilday, JP; Thomas, C; Hasselblatt, M; Kordes, UR; Adamski, J; Benesch, M; Obrecht-Sturm, D
CHOROID PLEXUS CARCINOMA IN PEDIATRIC PATIENTS WITH LI FRAUMENI SYNDROME (LFS) - CLINICAL COURSE AND THERAPEUTIC STRATEGIES
NEURO-ONCOLOGY. 2024; 26: NOAE064570--International Symposium on Pediatric Neuro-Oncology (ISPNO); JUN 29-JUL 02, 2024; Philadelphia, PA.
Doi: 10.1093/neuonc/noae064.570
[Oral Communication]
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** Pillay-Smiley, N; Nussbaumer, G; Damen-Corbijn, C; Baugh, J; Webster, A; Lane, A; Godschalk, TC; Grill, J; Hawkins, C; Leach, J; Janssens, G; Jones, B; Massimino, M; Karremann, M; van Vuurden, DG; Bailey, S; Das, A; Thomale, UW; Goldman, S; Perreault, S; Biassoni, V; Minturn, J; Hummel, T; Kramm, C; van Zanten, SV; Hoffman, LM
CLINICAL, RADIOGRAPHIC, HISTOPATHOLOGIC, AND MOLECULAR CHARACTERISTICS OF LONG-TERM SURVIVORS OF DIFFUSE INTRINSIC PONTINE GLIOMA-AN UPDATE FROM THE INTERNATIONAL AND EUROPEAN SOCIETY FOR PEDIATRIC ONCOLOGY DIPG REGISTRIES (IDIPGR/SIOPE-DIPGR)
NEURO-ONCOLOGY. 2024; 26: NOAE064144
Doi: 10.1093/neuonc/noae064.144
[Poster]
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** Tauziède-Espariat, A; Friker, LL; Nussbaumer, G; Alice, M; Antonelli, M; Benesch, M; Bison, B; Dangouloff-Ros, V; Garrè, ML; Giangaspero, F; Grabovska, Y; Grill, J; Jones, DTW; Jones, C; Karremann, M; Kramm, CM; Mackay, A; La Madrid, AM; Perwein, T; Pietsch, T; Sumerauer, D; van Vuurden, D; von Bueren, AO; Warmuth-Metz, M; Wesseling, P; Zamecnik, J; Castel, D; Gielen, GH; Varlet, P
PEDIATRIC-TYPE DIFFUSE HIGH-GRADE GLIOMA OF METHYLATION-BASED RTK2A AND RTK2B SUBCLASSES PRESENT DISTINCT RADIOLOGICAL AND HISTOMOLECULAR FEATURES
NEURO-ONCOLOGY. 2024; 26: NOAE064300--International Symposium on Pediatric Neuro-Oncology (ISPNO); JUN 29-JUL 02, 2024; Philadelphia, PA.
Doi: 10.1093/neuonc/noae064.300
[Oral Communication]
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2023
Full paper/article (Journal)
** Perwein, T; Giese, B; Nussbaumer, G; von, Bueren, AO; van, Buiren, M; Benesch, M; Kramm, CM
How I treat recurrent pediatric high-grade glioma (pHGG): a Europe-wide survey study.
J Neurooncol. 2023; 161(3):525-538
Doi: 10.1007/s11060-023-04241-6
[OPEN ACCESS]
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Case Report
** Nussbaumer, G; Benesch, M; Bokros, A; Brecht, IB; Speicher, I; Suppan, E; Tschauner, S; Vokuhl, C; Schneider, DT
Bilateral testicular juvenile granulosa cell tumor: Tumor control with conservative, antihormonal therapy.
Pediatr Blood Cancer. 2023; 70(2):e29895
Doi: 10.1002/pbc.29895
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Abstract (Journal)
** Nussbaumer, G; Benesch, M; Grabovska, Y; Mackay, A; Castel, D; Grill, J; Roldan, MMA; Antonelli, M; Bailey, S; Baugh, JN; Broniscer, A; Crampsie, S; Entz-Werle, N; Eyrich, M; Garre, ML; Gerber, NU; Giangaspero, F; Gil-da-Costa, MJ; Hargrave, D; Hauser, P; Herrlinger, U; Hoffmann, M; Jacobs, S; Karremann, M; Kattamis, A; Kebudi, R; Kwiecien, R; Massimino, M; Mastronuzzi, A; Pentikainen, V; Perwein, T; Pfister, SM; Pietsch, T; Sturm, D; Sumerauer, D; van Vuurden, D; von Bueren, AO; Varlet, P; van Zanten, SEMV; Vinci, M; Wesseling, MWMP; Wesseling, P; Wiese, M; Zamecnik, J; La Madrid, AM; Bison, B; Gielen, GH; Jones, DTW; Jones, C; Kramm, CM
GLIOMATOSIS CEREBRI IN CHILDREN: A POOR PROGNOSTIC, HIGHLY INFILTRATIVE PHENOTYPE OF DIFFUSE PEDIATRIC HIGH-GRADE GLIOMAS WITH DISTINCT MOLECULAR FEATURES
NEURO-ONCOLOGY. 2023; 25:
[Poster]
Web of Science
2022
Full paper/article (Journal)
** Gielen, GH; Baugh, JN; van, Vuurden, DG; Veldhuijzen, van, Zanten, SEM; Hargrave, D; Massimino, M; Biassoni, V; Morales, la, Madrid, A; Karremann, M; Wiese, M; Thomale, U; Janssens, GO; von, Bueren, AO; Perwein, T; Nussbaumer, G; Hoving, EW; Niehusmann, P; Gessi, M; Kwiecien, R; Bailey, S; Pietsch, T; Andreiuolo, F; Kramm, CM
Pediatric high-grade gliomas and the WHO CNS Tumor Classification-Perspectives of pediatric neuro-oncologists and neuropathologists in light of recent updates.
Neurooncol Adv. 2022; 4(1): vdac077
Doi: 10.1093/noajnl/vdac077
[OPEN ACCESS]
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Review
** Nussbaumer, G; Benesch, M
Hepatoblastoma in molecularly defined, congenital diseases.
Am J Med Genet A. 2022; 188(9):2527-2535
Doi: 10.1002/ajmg.a.62767
[OPEN ACCESS]
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Abstract (Journal)
** Nussbaumer, G; Benesch, M; Gielen, GH; Castel, D; Grill, J; Roldan, MMA; Antonelli, M; Bailey, S; Baugh, JN; Biassoni, V; Carai, A; Colditz, N; Colefati, GS; Corbacioglu, S; Crampsie, S; Entz-Werle, N; Eyrich, M; Fruhwald, MC; Garre, ML; Gerber, NU; Giangaspero, F; Gil-da-Costa, MJ; Grabovska, Y; Graf, N; Hargrave, D; Hauser, P; Hoffmann, M; Hulleman, E; Jacobs, S; Karremann, M; Kattamis, A; Kebudi, R; Kortmann, RD; Kwiecien, R; Mackay, A; Massimino, M; Miele, E; Mastronuzzi, A; Morana, G; Noack, CM; Pentikainen, V; Perwein, T; Pfister, SM; Pietsch, T; Roka, K; Rossi, S; Rutkowski, S; Schiavello, E; Sterba, J; Sturm, D; Sumerauer, D; Temelso, S; van Vuurden, D; Varlet, P; van Zanten, SEMV; Vinci, M; von Bueren, AO; Warmuth-Metz, M; Wesseling, P; Wiese, M; Wolff, JEA; Zamecnik, J; Jones, DTW; Bison, B; La Madrid, AM; Jones, C; Kramm, CM
GLIOMATOSIS CEREBRI IN CHILDREN: A COLLABORATIVE REPORT FROM THE EUROPEAN SOCIETY FOR PEDIATRIC ONCOLOGY (SIOPE)
NEURO-ONCOLOGY. 2022; 24: 72-73.-20th International Symposium on Pediatric Neuro-Oncology (ISPNO) 2022; JUN 12-15, 2022; Hamburg, GERMANY.
[Poster]
Web of Science
** Perwein, T; Giese, B; Nussbaumer, G; von Bueren, AO; van Buiren, M; Benesch, M; Kramm, CM
HOW I TREAT RECURRENT PEDIATRIC HIGH-GRADE GLIOMA (HGG): A EUROPE-WIDE SURVEY STUDY
NEURO-ONCOLOGY. 2022; 24: 67-67.-20th International Symposium on Pediatric Neuro-Oncology (ISPNO) 2022; JUN 12-15, 2022; Hamburg, GERMANY.
[Poster]
Web of Science
** von Bueren, AO; Kwiecien, R; Gielen, GH; Benesch, M; Perwein, T; Nussbaumer, G; Sturm, D; Jones, DTW; Pfister, SM; Eyrich, M; Rutkowski, S; Fleischhack, G; von Buiren, M; Karremann, M; Kortmann, RD; Hagel, C; Calaminus, G; Faldum, A; Bison, B; Pietsch, T; Hoffmann, M; Kramm, CM
FINAL ANALYSIS OF THE HIT-HGG-2007 TRIAL (ISRCTN19852453): SIGNIFICANT SURVIVAL BENEFIT FOR PONTINE AND NON-PONTINE PEDIATRIC HIGH-GRADE GLIOMAS IN COMPARISON TO PREVIOUS HIT-GBM-C/-D TRIALS
NEURO-ONCOLOGY. 2022; 24: 63-64.-20th International Symposium on Pediatric Neuro-Oncology (ISPNO) 2022; JUN 12-15, 2022; Hamburg, GERMANY.
[Poster]
Web of Science
2020
Full paper/article (Journal)
** Wiese, M; Hamdan, FH; Kubiak, K; Diederichs, C; Gielen, GH; Nussbaumer, G; Carcaboso, AM; Hulleman, E; Johnsen, SA; Kramm, CM
Combined treatment with CBP and BET inhibitors reverses inadvertent activation of detrimental super enhancer programs in DIPG cells.
CELL DEATH DIS. 2020; 11(8): 673-673.
Doi: 10.1038/s41419-020-02800-7
[OPEN ACCESS]
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2019
Abstract (Journal)
** Nussbaumer, G; Benesch, M; Gielen, G; Pietsch, T; Bison, B; Warmuth-Metz, M; Kortmann, RD; Krause, M; Gurtner, K; Von Bueren, AO; Kramm, C
Clinical Characteristics and Outcome of Children with Primarily Multicentric High-Grade Gliomas. A Retrospective Analysis
PEDIATR BLOOD CANCER. 2019; 66: S143-S143.
[Oral Communication]
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