Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Leopold Christina |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2021
Originalarbeit (Zeitschrift)
** Sachdev, V; Duta-Mare, M; Korbelius, M; Vujić, N; Leopold, C; Freark, de, Boer, J; Rainer, S; Fickert, P; Kolb, D; Kuipers, F; Radovic, B; Gorkiewicz, G; Kratky, D
Impaired Bile Acid Metabolism and Gut Dysbiosis in Mice Lacking Lysosomal Acid Lipase.
Cells. 2021; 10(10):
Doi: 10.3390/cells10102619
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** Wunderling, K; Leopold, C; Jamitzky, I; Yaghmour, M; Zink, F; Kratky, D; Thiele, C
Hepatic synthesis of triacylglycerols containing medium-chain fatty acids is dominated by diacylglycerol acyltransferase 1 and efficiently inhibited by etomoxir.
Mol Metab. 2020; 45: 101150-101150.
Doi: 10.1016/j.molmet.2020.101150
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2020
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** Goeritzer, M; Bernhart, E; Plastira, I; Reicher, H; Leopold, C; Eichmann, TO; Rechberger, G; Madreiter-Sokolowski, CT; Prasch, J; Eller, P; Graier, WF; Kratky, D; Malle, E; Sattler, W
Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro.
Int J Mol Sci. 2020; 21(3):
Doi: 10.3390/ijms21031143
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2019
Originalarbeit (Zeitschrift)
** Leopold, C; Duta-Mare, M; Sachdev, V; Goeritzer, M; Maresch, LK; Kolb, D; Reicher, H; Wagner, B; Stojakovic, T; Ruelicke, T; Haemmerle, G; Hoefler, G; Sattler, W; Kratky, D
Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(4):500-511
Doi: 10.1016/j.bbalip.2019.01.007
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** Maresch, LK; Benedikt, P; Feiler, U; Eder, S; Zierler, KA; Taschler, U; Kolleritsch, S; Eichmann, TO; Schoiswohl, G; Leopold, C; Wieser, BI; Lackner, C; Rülicke, T; van, Klinken, J; Kratky, D; Moustafa, T; Hoefler, G; Haemmerle, G
Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity.
Hepatol Commun. 2019; 3(2):227-245
Doi: 10.1002/hep4.1292
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2018
Originalarbeit (Zeitschrift)
** Duta-Mare, M; Sachdev, V; Leopold, C; Kolb, D; Vujic, N; Korbelius, M; Hofer, DC; Xia, W; Huber, K; Auer, M; Gottschalk, B; Magnes, C; Graier, WF; Prokesch, A; Radovic, B; Bogner-Strauss, JG; Kratky, D
Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis.
Biochim Biophys Acta. 2018; 1863(4):467-478
Doi: 10.1016/j.bbalip.2018.01.011
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** Speziali, G; Liesinger, L; Gindlhuber, J; Leopold, C; Pucher, B; Brandi, J; Castagna, A; Tomin, T; Krenn, P; Thallinger, GG; Olivieri, O; Martinelli, N; Kratky, D; Schittmayer, M; Birner-Gruenberger, R; Cecconi, D
Myristic acid induces proteomic and secretomic changes associated with steatosis, cytoskeleton remodeling, endoplasmic reticulum stress, protein turnover and exosome release in HepG2 cells.
J Proteomics. 2018; 181(7):118-130
Doi: 10.1016/j.jprot.2018.04.008
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Abstract (Zeitschrift)
** Duta-Mare, M; Sachdev, V; Leopold, C; Kolb, D; Vujic, N; Korbelius, M; Hofer, D; Xia, W; Huber, K; Magnes, C; Radovic, B; Bogner-Strauss, J; Kratky, D
LYSOSOMAL ACID LIPASE REGULATES FATTY ACID CHANNELING IN BROWN ADIPOSE TISSUE TO MAINTAIN THERMOGENESIS
ATHEROSCLEROSIS. 2018; 275: E15-E15.-86th Congress of the European-Atherosclerosis-Society (EAS); MAY 05-08, 2018; Lisbon, PORTUGAL.
Doi: 10.1016/j.atherosclerosis.2018.06.927
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** Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Doktorova, M; Scheicher, B; Goeritzer, M; Kolb, D; Turnbull, AV; Zimmer, A; Hoefler, G; Hussain, MM; Groen, AK; Kratky, D
NOVEL ROLE OF A TRIGLYCERIDE-SYNTHESIZING ENZYME: DGAT1 AT THE CROSSROAD BETWEEN TRIGLYCERIDE AND CHOLESTEROL METABOLISM
ATHEROSCLEROSIS. 2018; 275: E10-E11.-86th Congress of the European-Atherosclerosis-Society (EAS); MAY 05-08, 2018; Lisbon, PORTUGAL.
Doi: 10.1016/j.atherosclerosis.2018.06.915
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2017
Originalarbeit (Zeitschrift)
** Schlager, S; Vujic, N; Korbelius, M; Duta-Mare, M; Dorow, J; Leopold, C; Rainer, S; Wegscheider, M; Reicher, H; Ceglarek, U; Sattler, W; Radovic, B; Kratky, D
Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages.
Oncotarget. 2017; 8(25):40037-40051
Doi: 10.18632/oncotarget.16673
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** Vujic, N; Korbelius, M; Leopold, C; Duta-Mare, M; Rainer, S; Schlager, S; Goeritzer, M; Kolb, D; Eichmann, TO; Diwoky, C; Zimmer, A; Zimmermann, R; Lass, A; Radovic, B; Kratky, D
Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice.
Oncotarget. 2017; 8(20):33122-33136
Doi: 10.18632/oncotarget.16529
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Abstract (Zeitschrift)
** Leopold, C; Mashek, D; Kratky, D
THE ROLE OF LIPOPHAGY IN HEPATIC ENERGY METABOLISM
ATHEROSCLEROSIS. 2017; 263: E13-E14.-85th Congress of the European-Atherosclerosis-Society (EAS); APR 23-26, 2017; Prague, CZECH REPUBLIC.
Doi: 10.1016/j.atherosclerosis.2017.06.071
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** Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Boverhof, R; Doktorova, M; Scheicher, B; Kolb, D; Turnbull, AV; Zimmer, A; Hoefler, G; Hussain, MM; Groen, AK; Kratky, D
NOVEL ROLE OF A TRIGLYCERIDE-SYNTHESIZING ENZYME: DGAT1 AT THE CROSSROAD BETWEEN TRIGLYCERIDE AND CHOLESTEROL METABOLISM
ATHEROSCLEROSIS. 2017; 263: E7-E7.-85th Congress of the European-Atherosclerosis-Society (EAS); APR 23-26, 2017; Prague, CZECH REPUBLIC.
Doi: 10.1016/j.atherosclerosis.2017.06.048
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2016
Originalarbeit (Zeitschrift)
** Grumet, L; Eichmann, TO; Taschler, U; Zierler, KA; Leopold, C; Moustafa, T; Radovic, B; Romauch, M; Yan, C; Du, H; Haemmerle, G; Zechner, R; Fickert, P; Kratky, D; Zimmermann, R; Lass, A
Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover.
J Biol Chem. 2016; 291(34):17977-87
Doi: 10.1074/jbc.M116.724054
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** Radović, B; Vujić, N; Leopold, C; Schlager, S; Goeritzer, M; Patankar, JV; Korbelius, M; Kolb, D; Reindl, J; Wegscheider, M; Tomin, T; Birner-Gruenberger, R; Schittmayer, M; Groschner, L; Magnes, C; Diwoky, C; Frank, S; Steyrer, E; Du, H; Graier, WF; Madl, T; Kratky, D
Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice.
Diabetologia. 2016; 59(8):1743-1752
Doi: 10.1007/s00125-016-3968-6
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** Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Boverhof, R; Doktorova, M; Scheicher, B; Goeritzer, M; Kolb, D; Turnbull, AV; Zimmer, A; Hoefler, G; Hussain, MM; Groen, AK; Kratky, D
Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.
Biochim Biophys Acta. 2016; 1861(9 Pt A):1132-1141
Doi: 10.1016/j.bbalip.2016.06.014
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Abstract (Zeitschrift)
** Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Doktorova, M; Goeritzer, M; Scheicher, B; Kolb, D; Hoefler, G; Turnbull, AV; Zimmer, A; Hussain, MM; Groen, AK; Kratky, D
LIPOPROTEINS AND LIPID METABOLISM: APOB CONTAINING LIPOPROTEINS. NOVEL ROLE OF A TRIGLYCERIDE-SYNTHESIZING ENZYME: DGAT1 AT THE CROSSROAD BETWEEN TRIGLYCERIDE AND CHOLESTEROL METABOLISM
ATHEROSCLEROSIS. 2016; 252: E98-E99.-Congress of the European-Atherosclerosis-Society (EAS); MAY 29-JUN 01, 2016; Innsbruck, AUSTRIA.
Doi: 10.1016/j.atherosclerosis.2016.07.564
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2015
Originalarbeit (Zeitschrift)
** Dražić, T; Sachdev, V; Leopold, C; Patankar, JV; Malnar, M; Hećimović, S; Levak-Frank, S; Habuš, I; Kratky, D
Synthesis and evaluation of novel amide amino-β-lactam derivatives as cholesterol absorption inhibitors.
Bioorg Med Chem. 2015; 23(10):2353-2359
Doi: 10.1016/j.bmc.2015.03.067
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** Goeritzer, M; Vujic, N; Schlager, S; Chandak, PG; Korbelius, M; Gottschalk, B; Leopold, C; Obrowsky, S; Rainer, S; Doddapattar, P; Aflaki, E; Wegscheider, M; Sachdev, V; Graier, WF; Kolb, D; Radovic, B; Kratky, D
Active autophagy but not lipophagy in macrophages with defective lipolysis.
Biochim Biophys Acta. 2015; 1851(10):1304-1316
Doi: 10.1016/j.bbalip.2015.06.005
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