** = Publikationen gelistet in SCI/SSCI/Pubmed
** Gruden, E; Kienzl, M; Danner, L; Kaspret, DM; Pammer, A; Ristic, D; Kindler, O; Doyle, AD; Wright, BL; Taschler, U; Thomas, D; Gurke, R; Baumann-Durchschein, F; Konrad, J; Blesl, A; Schlager, H; Bärnthaler, T; Kargl, J; Schicho, R
The endocannabinoid system drives eosinophil infiltration during eosinophilic esophagitis.
Cell Mol Gastroenterol Hepatol. 2025; 101515
Doi: 10.1016/j.jcmgh.2025.101515
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** Rajesh, R; Mooslechner, AA; Schweighofer, H; Pahernik, S; Lanz, I; Atallah, R; Platzer, W; Aigner, C; Benazzo, A; Angiari, S; Marsh, L; Kwapiszewska, G; Heinemann, A; Bärnthaler, T
Succinate aggravates pulmonary fibrosis through the succinate/SUCNR1 axis.
Am J Physiol Lung Cell Mol Physiol. 2025;
Doi: 10.1152/ajplung.00286.2024
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** Ristić, D; Bärnthaler, T; Gruden, E; Kienzl, M; Danner, L; Herceg, K; Sarsembayeva, A; Kargl, J; Schicho, R
GPR55 in the tumor microenvironment of pancreatic cancer controls tumorigenesis.
Front Immunol. 2024; 15: 1513547
Doi: 10.3389/fimmu.2024.1513547
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** Tatzl, E; Petracco, G; Faimann, I; Balasso, M; Mooslechner, AA; Bärnthaler, T; Rodriguez-Blanco, G; Reichmann, F
Deficiency of the Synaptic Adhesion Protein Leucine-Rich Repeat Transmembrane Protein 4 Like 1 Affects Anxiety and Aggression in Zebrafish.
Acta Physiol (Oxf). 2025; 241(5):e70042
Doi: 10.1111/apha.70042
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** Teppan, J; Bärnthaler, T; Farzi, A; Durrington, H; Gioan-Tavernier, G; Platt, H; Wolf, P; Heinemann, A; Böhm, EM
The molecular circadian clock of eosinophils: A potential therapeutic target for asthma.
Am J Physiol Cell Physiol. 2025;
Doi: 10.1152/ajpcell.00149.2025
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** Manning, EP; Ramachandra, AB; Sharma, P; Nikola, F; De Man, R; Doddaballapur, P; Raredon, MB; Szafron, J; Baernthaler, T; Justet, A; Akingbesote, N; Perry, RJ; Adams, T; Cavinato, C; Yan, X; Tellides, G; Kaminski, N; Humphrey, JD
Understanding and Reducing Cardiopulmonary Sequelae Associated With Chronic Hypoxia
AM J RESP CRIT CARE. 2025; 211: A3336
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** Bärnthaler, T; Ramachandra, AB; Ebanks, S; Guerrera, N; Sharma, L; Dela, Cruz, CS; Humphrey, JD; Manning, EP
Developmental changes in lung function of mice are independent of sex as a biological variable.
Am J Physiol Lung Cell Mol Physiol. 2024;
Doi: 10.1152/ajplung.00120.2023
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** Stadler, JT; Bärnthaler, T; Borenich, A; Emrich, IE; Habisch, H; Rani, A; Holzer, M; Madl, T; Heine, GH; Marsche, G
Low LCAT activity is linked to acute decompensated heart failure and mortality in patients with CKD.
J Lipid Res. 2024; 65(9):100624
Doi: 10.1016/j.jlr.2024.100624
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** Teppan, J; Schwanzer, J; Rittchen, S; Bärnthaler, T; Lindemann, J; Nayak, B; Reiter, B; Luschnig, P; Farzi, A; Heinemann, A; Sturm, E
The disrupted molecular circadian clock of monocytes and macrophages in allergic inflammation.
Front Immunol. 2024; 15: 1408772
Doi: 10.3389/fimmu.2024.1408772
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** Mooslechner, AA; Klötzer, KA; Habisch, H; Madl, T; Rosenkranz, AR; Bärnthaler, T; Eller, K
Enhanced Renal Tissue Regeneration and Functional Recovery with IL-15 Treatment in Acute Kidney Injury
EUR J IMMUNOL. 2024; 54: 1560-1560.-7th European Conference of Immunology; SEP 01-04, 2024; Dublin, IRELAND.
[Poster]
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** Ahangari, F; Price, NL; Malik, S; Chioccioli, M; Barnthaler, T; Adams, TS; Kim, J; Pradeep, SP; Ding, SZ; Cosmos, CC; Rose, KAS; McDonough, JE; Aurelien, NR; Ibarra, G; Omote, N; Schupp, JC; DeIuliis, G; Nunez, JAV; Sharma, L; Ryu, C; Cruz, CSD; Liu, XR; Prasse, A; Rosas, I; Bahal, R; Fernandez-Hernando, C; Kaminski, N
microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis
JCI INSIGHT. 2023; 8(4): e158100
Doi: 10.1172/jci.insight.158100
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** Berger, N; van, der, Wel, T; Hirschmugl, B; Baernthaler, T; Gindlhuber, J; Fawzy, N; Eichmann, T; Birner-Gruenberger, R; Zimmermann, R; van, der, Stelt, M; Wadsack, C
Inhibition of diacylglycerol lipase β modulates lipid and endocannabinoid levels in the ex vivo human placenta.
Front Endocrinol (Lausanne). 2023; 14: 1092024
Doi: 10.3389/fendo.2023.1092024
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** Paar, M; Aziz, F; Sourij, C; Tripolt, NJ; Kojzar, H; Müller, A; Pferschy, P; Obermayer, A; Banfic, T; Di, Geronimo, Quintero, B; Goswami, N; Schlagenhauf, A; Köstenberger, M; Bärnthaler, T; Wagner, T; Hrzenjak, A; Wonisch, W; Reibnegger, G; Raggam, RB; Sourij, H; Cvirn, G
Only Subclinical Alterations in the Haemostatic System of People with Diabetes after COVID-19 Vaccination.
Viruses. 2023; 15(1): 10
Doi: 10.3390/v15010010
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** Schoerghuber, M; Bärnthaler, T; Prüller, F; Mantaj, P; Cvirn, G; Toller, W; Klivinyi, C; Mahla, E; Heinemann, A
Supplemental fibrinogen restores thrombus formation in cardiopulmonary bypass-induced platelet dysfunction ex vivo.
Br J Anaesth. 2023; 131(3):452-462
Doi: 10.1016/j.bja.2023.03.010
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** Stadler, JT; Habisch, H; Prüller, F; Mangge, H; Bärnthaler, T; Kargl, J; Pammer, A; Holzer, M; Meissl, S; Rani, A; Madl, T; Marsche, G
HDL-Related Parameters and COVID-19 Mortality: The Importance of HDL Function.
Antioxidants (Basel). 2023; 12(11):
Doi: 10.3390/antiox12112009
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** Rajesh, R; Atallah, R; Baernthaler, T
Dysregulation of metabolic pathways in pulmonary fibrosis
PHARMACOL THERAPEUT. 2023; 246: 108436
Doi: 10.1016/j.pharmthera.2023.108436
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** Rajesh, R; Atallah, R; Lanz, I; Platzer, W; Angiari, S; Marsh, L; Bärnthaler, T; Heinemann, A
Succinate aggravates pulmonary fibrosis through the succinate/SUCNR1 axis.
EUR RESPIR J. Abstracts. 2023; 62(Suppl67):PA2359--ERS International Congress 2023; SEP 9-13, 2023; Milan, ITALY.
Doi: 10.1183/13993003.congress-2023.PA2359
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** Rani, A; Baladin, D; Teppan, J; Kienzl, M; Jandl, K; Bärnthaler, T; Lanz, I; Stadler, J; Böhm, E; Prassl, R; Marsche, G
Synthetic HDL-nanodiscs as a drug-candidate in pulmonary inflammation
WIEN KLIN WOCHENSCHR. Abstracts. 2023; 135(19-20):566-566.-47. Jahrestagung der ÖGP - 7. Jahrestagung der ÖGTC; OCT 23-25, 2023; Graz, Austria.
[Poster]
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** Ahangari, F; Becker, C; Foster, DG; Chioccioli, M; Nelson, M; Beke, K; Wang, X; Justet, A; Adams, T; Readhead, B; Meador, C; Correll, K; Lili, LN; Roybal, HM; Rose, KA; Ding, SZ; Barnthaler, T; Briones, N; DeIuliis, G; Schupp, JC; Li, Q; Omote, N; Aschner, Y; Sharma, L; Kopf, KW; Magnusson, B; Hicks, R; Backmark, A; Dela Cruz, CS; Rosas, I; Cousens, LP; Dudley, JT; Kaminski, N; Downey, GP
Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis
AM J RESP CRIT CARE. 2022; 206(12): 1463-1479.
Doi: 10.1164/rccm.202010-3832OC
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** Sauler, M; McDonough, JE; Adams, TS; Kothapalli, N; Barnthaler, T; Werder, RB; Schupp, JC; Nouws, J; Robertson, MJ; Coarfa, C; Yang, T; Chioccioli, M; Omote, N; Cosme, C; Poli, S; Ayaub, EA; Chu, SG; Jensen, KH; Gomez, JL; Britto, CJ; Raredon, MSB; Niklason, LE; Wilson, AA; Timshel, PN; Kaminski, N; Rosas, IO
Characterization of the COPD alveolar niche using single-cell RNA sequencing.
Nat Commun. 2022; 13(1): 494
Doi: 10.1038/s41467-022-28062-9
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** Berger, N; Barnthaler, T; Gindlhuber, J; Girgis, N; Van der Wel, T; Hirschmugl, B; Birner-Gruenberger, R; Van der Stelt, M; Wadsack, C
DAGL beta Activity Determines Endocannabinoid Biosynthesis and Arachidonic Acid Supply in the Human Placenta
REPROD SCI. 2022; 29(SUPPL 1): 158-159.
[Poster]
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** Aringer, I; Artinger, K; Schabhüttl, C; Bärnthaler, T; Mooslechner, AA; Kirsch, A; Pollheimer, M; Eller, P; Rosenkranz, AR; Heinemann, A; Eller, K
Agonism of Prostaglandin E2 Receptor 4 Ameliorates Tubulointerstitial Injury in Nephrotoxic Serum Nephritis in Mice.
J Clin Med. 2021; 10(4):
Doi: 10.3390/jcm10040832
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** Atallah, R; Gindlhuber, J; Platzer, W; Bärnthaler, T; Tatzl, E; Toller, W; Strutz, J; Rittchen, S; Luschnig, P; Birner-Gruenberger, R; Wadsack, C; Heinemann, A
SUCNR1 Is Expressed in Human Placenta and Mediates Angiogenesis: Significance in Gestational Diabetes.
Int J Mol Sci. 2021; 22(21):
Doi: 10.3390/ijms222112048
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** Kienzl, M; Hasenoehrl, C; Maitz, K; Sarsembayeva, A; Taschler, U; Valadez-Cosmes, P; Kindler, O; Ristic, D; Raftopoulou, S; Santiso, A; Bärnthaler, T; Brcic, L; Hahnefeld, L; Gurke, R; Thomas, D; Geisslinger, G; Kargl, J; Schicho, R
Monoacylglycerol lipase deficiency in the tumor microenvironment slows tumor growth in non-small cell lung cancer.
Oncoimmunology. 2021; 10(1): 1965319
Doi: 10.1080/2162402X.2021.1965319
[OPEN ACCESS]
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** Manning, EP; Ramachandra, AB; Schupp, JC; Cavinato, C; Raredon, MSB; Bärnthaler, T; Cosme, C; Singh, I; Tellides, G; Kaminski, N; Humphrey, JD
Mechanisms of Hypoxia-Induced Pulmonary Arterial Stiffening in Mice Revealed by a Functional Genetics Assay of Structural, Functional, and Transcriptomic Data.
Front Physiol. 2021; 12:726253
Doi: 10.3389/fphys.2021.726253
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** Rittchen, S; Jandl, K; Lanz, I; Reiter, B; Ferreirós, N; Kratz, D; Lindenmann, J; Brcic, L; Bärnthaler, T; Atallah, R; Olschewski, H; Sturm, EM; Heinemann, A
Monocytes and Macrophages Serve as Potent Prostaglandin D2 Sources during Acute, Non-Allergic Pulmonary Inflammation.
Int J Mol Sci. 2021; 22(21): 11697
Doi: 10.3390/ijms222111697
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** Berger, N; Barnthaler, T; Gindlhuber, J; Girgis, N; Hirschmugl, B; van der Wel, T; Zimmermann, R; Birner-Gruenberger, R; van der Stelt, M; Wadsack, C;
PLACENTAL DAGL beta REGULATES 2-ARACHIDONOYLGLYCEROL (2-AG) LEVELS AND IS INVOLVED IN PREGNANCY INDUCED INFLAMMATION.
PLACENTA. 2021; 112: E41-E42.
[Onlinepräsentation]
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** Berger, N; Barnthaler, T; Gindlhuber, J; Girgis, N; van der Wel, T; Hirschmugl, B; Birner-Gruenberger, R; van der Stelt, M; Zimmermann, R; Wadsack, C;
Placental DAGLbeta Regulates 2-arachidonoylglycerol Levels and Is Involved in Pregnancy Induced Inflammation.
REPROD SCI. 2021; 28(SUPPL 1):279A-280A.
[Onlinepräsentation]
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** Bärnthaler, T; Mahla, E; Toth, GG; Schuligoi, R; Prüller, F; Buschmann, E; Heinemann, A
Supplemental Fibrinogen Restores Platelet Inhibitor-Induced Reduction in Thrombus Formation without Altering Platelet Function: An In Vitro Study.
Thromb Haemost. 2020; 120(11):1548-1556
Doi: 10.1055/s-0040-1715445
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** Bärnthaler, T; Theiler, A; Zabini, D; Trautmann, S; Stacher-Priehse, E; Lanz, I; Klepetko, W; Sinn, K; Flick, H; Scheidl, S; Thomas, D; Olschewski, H; Kwapiszewska, G; Schuligoi, R; Heinemann, A
Inhibiting eicosanoid degradation exerts antifibrotic effects in a pulmonary fibrosis mouse model and human tissue.
J Allergy Clin Immunol. 2020; 145(3):818-833
Doi: 10.1016/j.jaci.2019.11.032
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** Knuplez, E; Curcic, S; Theiler, A; Bärnthaler, T; Trakaki, A; Trieb, M; Holzer, M; Heinemann, A; Zimmermann, R; Sturm, EM; Marsche, G
Lysophosphatidylcholines inhibit human eosinophil activation and suppress eosinophil migration in vivo.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020; 1865(7):158686-158686
Doi: 10.1016/j.bbalip.2020.158686
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** Rittchen, S; Rohrer, K; Platzer, W; Knuplez, E; Bärnthaler, T; Marsh, LM; Atallah, R; Sinn, K; Klepetko, W; Sharma, N; Nagaraj, C; Heinemann, A
Prostaglandin D2 strengthens human endothelial barrier by activation of E-type receptor 4.
Biochem Pharmacol. 2020; 182(12):114277-114277
Doi: 10.1016/j.bcp.2020.114277
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** Theiler, A; Bärnthaler, T; Platzer, W; Richtig, G; Peinhaupt, M; Rittchen, S; Kargl, J; Ulven, T; Marsh, LM; Marsche, G; Schuligoi, R; Sturm, EM; Heinemann, A
Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival.
J Allergy Clin Immunol. 2019; 144(3):764-776
Doi: 10.1016/j.jaci.2019.05.002
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** Bärnthaler, T; Jandl, K; Sill, H; Uhl, B; Schreiber, Y; Grill, M; Thomas, D; Schicho, R; Marsche, G; Frank, S; Heinemann, A; Schuligoi, R
Imatinib stimulates prostaglandin E2 and attenuates cytokine release via EP4 receptor activation.
J Allergy Clin Immunol. 2019; 143(2):794-797
Doi: 10.1016/j.jaci.2018.09.030
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** Baernthaler, T; Theiler, A; Lanz, I; Thomas, D; Jandl, K; Kwapiszewska, G; Schuligoi, R; Heinemann, A
Inhibiting Prostaglandin E2 Degradation Is Protective in a Mouse Model of Pulmonary Fibrosis
AM J RESP CRIT CARE. 2019; 199: -International Conference of the American-Thoracic-Society; MAY 17-22, 2019; Dallas, TX.
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** Aringer, I; Artinger, K; Kirsch, AH; Schabhüttl, C; Jandl, K; Bärnthaler, T; Mooslechner, AA; Herzog, SA; Uhlig, M; Kirsch, A; Frank, S; Banas, M; Pollheimer, M; Eller, P; Rosenkranz, AR; Heinemann, A; Eller, K
Blockade of prostaglandin E2 receptor 4 ameliorates nephrotoxic serum nephritis.
Am J Physiol Renal Physiol. 2018; 315(6):F1869-F1880
Doi: 10.1152/ajprenal.00113.2018
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** Biasin, V; Wygrecka, M; Bärnthaler, T; Jandl, K; Jain, PP; Bálint, Z; Kovacs, G; Leitinger, G; Kolb-Lenz, D; Kornmueller, K; Peters, F; Sinn, K; Klepetko, W; Heinemann, A; Olschewski, A; Becker-Pauly, C; Kwapiszewska, G
Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation.
Thromb Haemost. 2018; 118(10):1790-1802
Doi: 10.1055/s-0038-1670657
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** Hasenoehrl, C; Feuersinger, D; Sturm, EM; Bärnthaler, T; Heitzer, E; Graf, R; Grill, M; Pichler, M; Beck, S; Butcher, L; Thomas, D; Ferreirós, N; Schuligoi, R; Schweiger, C; Haybaeck, J; Schicho, R
G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1.
Int J Cancer. 2018; 142(1):121-132
Doi: 10.1002/ijc.31030
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** Theiler, A; Platzer, W; Richtig, G; Peinhaupt, M; Barnthaler, T; Schuligoi, R; Sturm, EM; Heinemann, A
Short chain fatty acids (SCFA) activate the intrinsic apoptosis pathway in eosinophils from atopic individuals
ALLERGY. 2018; 73: 89-89.-Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI); MAY 26-30, 2018; Munich, GERMANY.
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** Bärnthaler, T; Maric, J; Platzer, W; Konya, V; Theiler, A; Hasenöhrl, C; Gottschalk, B; Trautmann, S; Schreiber, Y; Graier, WF; Schicho, R; Marsche, G; Olschewski, A; Thomas, D; Schuligoi, R; Heinemann, A
The Role of PGE2 in Alveolar Epithelial and Lung Microvascular Endothelial Crosstalk.
Sci Rep. 2017; 7(1):7923-7923
Doi: 10.1038/s41598-017-08228-y
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** Theiler, A; Konya, V; Pasterk, L; Maric, J; Bärnthaler, T; Lanz, I; Platzer, W; Schuligoi, R; Heinemann, A
The EP1/EP3 receptor agonist 17-pt-PGE2 acts as an EP4 receptor agonist on endothelial barrier function and in a model of LPS-induced pulmonary inflammation.
Vascul Pharmacol. 2016; 87(4):180-189
Doi: 10.1016/j.vph.2016.09.008
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** Barnthaler, T; Maric, J; Konya, V; Lanz, I; Platzer, W; Schuligoi, R; Heinemann, A
PGE2 released by alveolar epithelial cells protects the pulmonary endothelial barrier integrity
ALLERGY. 2016; 71: 169-169.-Meeting of the European-Academy-of-Allergy-and-Clinical-Immunology; JUN 11-15, 2016; Vienna, AUSTRIA.
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** Konya, V; Maric, J; Jandl, K; Luschnig, P; Aringer, I; Lanz, I; Platzer, W; Theiler, A; Bärnthaler, T; Frei, R; Marsche, G; Marsh, LM; Olschewski, A; Lippe, IT; Heinemann, A; Schuligoi, R
Activation of EP4 receptors prevents endotoxin-induced neutrophil infiltration into the airways and enhances microvascular barrier function.
Br J Pharmacol. 2015; 172(18):4454-4468
Doi: 10.1111/bph.13229
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