Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Plastira Ioanna |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2022
Originalarbeit (Zeitschrift)
** Joshi, L; Plastira, I; Bernhart, E; Reicher, H; Koshenov, Z; Graier, WF; Vujic, N; Kratky, D; Rivera, R; Chun, J; Sattler, W
Lysophosphatidic Acid Receptor 5 (LPA5) Knockout Ameliorates the Neuroinflammatory Response In Vivo and Modifies the Inflammatory and Metabolic Landscape of Primary Microglia In Vitro.
Cells. 2022; 11(7):
Doi: 10.3390/cells11071071
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2021
Originalarbeit (Zeitschrift)
** Joshi, L; Plastira, I; Bernhart, E; Reicher, H; Koyani, CN; Madl, T; Madreiter-Sokolowski, C; Koshenov, Z; Graier, WF; Hallström, S; Sattler, W
Lysophosphatidic Acid Induces Aerobic Glycolysis, Lipogenesis, and Increased Amino Acid Uptake in BV-2 Microglia.
Int J Mol Sci. 2021; 22(4):
Doi: 10.3390/ijms22041968
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** Joshi, L; Plastira, I; Bernhart, E; Reicher, H; Triebl, A; Kofeler, HC; Sattler, W
Inhibition of Autotaxin and Lysophosphatidic Acid Receptor 5 Attenuates Neuroinflammation in LPS-Activated BV-2 Microglia and a Mouse Endotoxemia Model
INT J MOL SCI. 2021; 22(16): 8519
Doi: 10.3390/ijms22168519
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2020
Originalarbeit (Zeitschrift)
** Goeritzer, M; Bernhart, E; Plastira, I; Reicher, H; Leopold, C; Eichmann, TO; Rechberger, G; Madreiter-Sokolowski, CT; Prasch, J; Eller, P; Graier, WF; Kratky, D; Malle, E; Sattler, W
Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro.
Int J Mol Sci. 2020; 21(3):
Doi: 10.3390/ijms21031143
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** Koyani, CN; Plastira, I; Sourij, H; Hallström, S; Schmidt, A; Rainer, PP; Bugger, H; Frank, S; Malle, E; von, Lewinski, D
Empagliflozin protects heart from inflammation and energy depletion via AMPK activation.
Pharmacol Res. 2020; 158:104870
Doi: 10.1016/j.phrs.2020.104870
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** Plastira, I; Bernhart, E; Joshi, L; Koyani, CN; Strohmaier, H; Reicher, H; Malle, E; Sattler, W
MAPK signaling determines lysophosphatidic acid (LPA)-induced inflammation in microglia.
J Neuroinflammation. 2020; 17(1): 127-127.
Doi: 10.1186/s12974-020-01809-1
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2019
Originalarbeit (Zeitschrift)
** Bhat, VK; Bernhart, E; Plastira, I; Fan, K; Ghaffari-Tabrizi-Wizsy, N; Wadsack, C; Rechberger, G; Eichmann, T; Asslaber, M; Spassova, I; Verhaegen, ME; Malle, E; Becker, JC; Sattler, W
Pharmacological Inhibition of Serine Palmitoyl Transferase and Sphingosine Kinase-1/-2 Inhibits Merkel Cell Carcinoma Cell Proliferation.
J Invest Dermatol. 2019; 139(4):807-817
Doi: 10.1016/j.jid.2018.10.024
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** Plastira, I; Joshi, L; Bernhart, E; Schoene, J; Specker, E; Nazare, M; Sattler, W
Small-Molecule Lysophosphatidic Acid Receptor 5 (LPAR5) Antagonists: Versatile Pharmacological Tools to Regulate Inflammatory Signaling in BV-2 Microglia Cells.
Front Cell Neurosci. 2019; 13: 531-531.
Doi: 10.3389/fncel.2019.00531
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2018
Originalarbeit (Zeitschrift)
** Bernhart, E; Kogelnik, N; Prasch, J; Gottschalk, B; Goeritzer, M; Depaoli, MR; Reicher, H; Nusshold, C; Plastira, I; Hammer, A; Fauler, G; Malli, R; Graier, WF; Malle, E; Sattler, W
2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells.
Redox Biol. 2018; 15:441-451
Doi: 10.1016/j.redox.2018.01.003
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** Koyani, CN; Trummer, C; Shrestha, N; Scheruebel, S; Bourgeois, B; Plastira, I; Kickmaier, S; Sourij, H; Rainer, PP; Madl, T; Sattler, W; Pelzmann, B; Malle, E; von Lewinski, D
Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes.
Front Physiol. 2018; 9:1622-1622
Doi: 10.3389/fphys.2018.01622
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** Ryu, JK; Rafalski, VA; Meyer-Franke, A; Adams, RA; Poda, SB; Rios Coronado, PE; Pedersen, LØ; Menon, V; Baeten, KM; Sikorski, SL; Bedard, C; Hanspers, K; Bardehle, S; Mendiola, AS; Davalos, D; Machado, MR; Chan, JP; Plastira, I; Petersen, MA; Pfaff, SJ; Ang, KK; Hallenbeck, KK; Syme, C; Hakozaki, H; Ellisman, MH; Swanson, RA; Zamvil, SS; Arkin, MR; Zorn, SH; Pico, AR; Mucke, L; Freedman, SB; Stavenhagen, JB; Nelson, RB; Akassoglou, K
Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration.
NAT IMMUNOL. 2018; 19(11): 1212-1223.
Doi: 10.1038/s41590-018-0232-x
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Abstract (Zeitschrift)
** Koyani, C; Trummer, C; Plastira, I; Lechleitner, M; Scherubel, S; Sourij, H; Sasa, F; Sattler, W; Malle, E; von Lewinski, D
Withaferin A attenuates inflammatory response and cardiovascular dysfunction induced by LPS
WIEN KLIN WOCHENSCHR. 2018; 130: 42-42.
[Poster]
Web of Science
Abstract (Konferenzband)
** Koyani, CN; Trummer, C; Plastira, I; Lechleitner, M; Sourij, H; Frank, S; Sattler, W; Malle, E ; von Lewinski, D
Withaferin A attenuates inflammatory response and cardiovascular
dysfunction induced by LPS
Eur J Heart Failure. 2018; 20(S1):167-167.-Heart Failure Association der ESC; MAY 26-29, 2018; Vienna, Austria.
[Poster]
Web of Science
2017
Originalarbeit (Zeitschrift)
** Plastira, I; Bernhart, E; Goeritzer, M; DeVaney, T; Reicher, H; Hammer, A; Lohberger, B; Wintersperger, A; Zucol, B; Graier, WF; Kratky, D; Malle, E; Sattler, W
Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype.
J Neuroinflammation. 2017; 14(1):253-253
Doi: 10.1186/s12974-017-1024-1
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Abstract (Zeitschrift)
** Plastira, J; Bernhart, E; Zucol, B; Graier, W; Sattler, W
Lysophosphatidic acid (LPA) controls the migratory and inflammatory response of microglia via the LPAR5-PKDs axis
GLIA. 2017; 65: E480-E480.-13th European Meeting on Glial Cells in Health and Disease; JUL 08-11, 2017; Edinburgh, SCOTLAND.
[Poster]
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2016
Originalarbeit (Zeitschrift)
** Nusshold, C; Üllen, A; Kogelnik, N; Bernhart, E; Reicher, H; Plastira, I; Glasnov, T; Zangger, K; Rechberger, G; Kollroser, M; Fauler, G; Wolinski, H; Weksler, BB; Romero, IA; Kohlwein, SD; Couraud, PO; Malle, E; Sattler, W
Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal.
Free Radic Biol Med. 2016; 90: 59-74.
Doi: 10.1016/j.freeradbiomed.2015.11.010
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** Plastira, I; Bernhart, E; Goeritzer, M; Reicher, H; Kumble, VB; Kogelnik, N; Wintersperger, A; Hammer, A; Schlager, S; Jandl, K; Heinemann, A; Kratky, D; Malle, E; Sattler, W
1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype.
J Neuroinflammation. 2016; 13(1): 205-205.
Doi: 10.1186/s12974-016-0701-9
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Abstract (Zeitschrift)
** Bhat Kumble, V; Bernhart, E; Plastira, I; Kogelnik, N; Goritzer, M; Fan, K; Wadsack, C; Rechberger, G; Becker, J; Sattler, W
Merkel cell carcinoma proliferation is regulated by sphingosine-1-phosphate-mediated pathways in vitro.
J INVEST DERMATOL. 2016; 136(9):S243-S243.-Annual Meeting of the European-Society-for-Dermatological-Research (ESDR); SEP 07-10, 2016; Munich, GERMANY.
[Poster]
Web of Science
2015
Originalarbeit (Zeitschrift)
** Bernhart, E; Damm, S; Wintersperger, A; Nusshold, C; Brunner, AM; Plastira, I; Rechberger, G; Reicher, H; Wadsack, C; Zimmer, A; Malle, E; Sattler, W
Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells.
Biochem Pharmacol. 2015; 96(2): 119-130.
Doi: 10.1016/j.bcp.2015.05.007
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