Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Kühn Klaus-Dieter |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2025
Originalarbeit (Zeitschrift)
** Frank, FA; Krampitz, B; Steiner, J; Strathausen, R; Morgenstern, M; Clauss, M; Kühn, KD
Evaluation and testing of polymethylmetacrylic (PMMA) bone cements with admixed Amphotericin B
J ORTHOP SURG RES. 2025; 20(1): 151
Doi: 10.1186/s13018-025-05565-x
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** Humez, M; Citak, M; Luck, S; Linke, P; Gehrke, T; Paul, C; Kühn, KD
Enhancing PMMA Cements With Manually Added Antimicrobial Agents.
APMIS. 2025; 133(5):e70029
Doi: 10.1111/apm.70029
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Korrektur
** Frank, FA; Krampitz, B; Steiner, J; Strathausen, R; Morgenstern, M; Clauss, M; Kühn, KD
Correction: Evaluation and testing of polymethylmetacrylic (PMMA) bone cements with admixed Amphotericin B.
J Orthop Surg Res. 2025; 20(1):325
Doi: 10.1186/s13018-025-05643-0
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2024
Originalarbeit (Zeitschrift)
** Abramowicz, M; Trampuz, A; Kühn, KD
Tigecycline Containing Polymethylmethacrylate Cement Against MRSA, VRE, and ESBL-In Vitro Mechanical and Microbiological Investigations.
Antibiotics (Basel). 2024; 13(11):
Doi: 10.3390/antibiotics13111102
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** Egger, V; Dammerer, D; Degenhart, G; Pallua, JD; Schmölz, W; Thaler, M; Kühn, KD; Nogler, M; Putzer, D
Does the Addition of Low-Dose Antibiotics Compromise the Mechanical Properties of Polymethylmethacrylate (PMMA)?
Polymers (Basel). 2024; 16(16):
Doi: 10.3390/polym16162378
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** Fölsch, C; Schirmer, J; Glameanu, C; Ishaque, B; Ulloa, CAF; Harz, T; Rickert, M; Martin, JR; Scherberich, J; Steinbart, J; Krombach, G; Paul, C; Kühn, KD; Jahnke, A; Homb, B
Cement Viscosity and Application Time Lead to Significant Changes in Cement Penetration and Contact Surface Area
ARTHROPLAST TODAY. 2024; 30: 101476
Doi: 10.1016/j.artd.2024.101476
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** Humez, M; Kötter, K; Skripitz, R; Kühn, KD
Evidence for cemented TKA and THA based on a comparison of international register data
ORTHOPADIE. 2024;
Doi: 10.1007/s00132-024-04489-4
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** Kittinger, C; Eder-Halbedl, M; Kühn, KD
Impact of Manual Addition of Vancomycin to Polymethylmethacrylate (PMMA) Cements.
Antibiotics (Basel). 2024; 13(8): 721
Doi: 10.3390/antibiotics13080721
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** Kittinger, C; Stadler, J; Kühn, KD
Evaluation of Gentamicin Release of PMMA Cements Using Different Methods: HPLC, Elution and Inhibition Zone Testing.
Antibiotics (Basel). 2024; 13(8): 754
Doi: 10.3390/antibiotics13080754
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** Kühn, KD; Coraça-Huber, DC; Erdtmann, M; Bernhardt, GA; Fölsch, C
Novel antimicrobial coating for hernia meshes.
Front Cell Infect Microbiol. 2024; 14:1383680
Doi: 10.3389/fcimb.2024.1383680
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** Kwong, JW; Abramowicz, M; Kühn, KD; Foelsch, C; Hansen, EN
High and Low Dosage of Vancomycin in Polymethylmethacrylate Cements: Efficacy and Mechanical Properties
ANTIBIOTICS-BASEL. 2024; 13(9): 818
Doi: 10.3390/antibiotics13090818
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Übersichtsarbeit
** Hawellek, T; von, Lewinski, G; Lehmann, W; Kühn, KD
[Cement in revision arthroplasty-what about the "glacier effect"? : Case studies viewed from different perspectives].
Orthopadie (Heidelb). 2023;
Doi: 10.1007/s00132-023-04452-9
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** Humez, M; Kötter, K; Skripitz, R; Kühn, KD
[Register data on cemented arthroplasty : A proof for cementless fixation?].
Orthopadie (Heidelb). 2023;
Doi: 10.1007/s00132-023-04451-w
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Editorial
** von Lewinski, G; Kühn, KD
PMMA Bone Cement-Part 2
ORTHOPADIE. 2024; 53(3): 161-162.
Doi: 10.1007/s00132-023-04457-4
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Korrektur
** Humez, M; Kötter, K; Skripitz, R; Kühn, KD
Evidence for cemented TKA and THA based on a comparison of international register data (Apr, 10.1007/s00132-024-04489-4, 2024)
ORTHOPADIE. 2024;
Doi: 10.1007/s00132-024-04513-7
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** Humez, M; Kötter, K; Skripitz, R; Kühn, KD
Erratum to: Evidence for cemented TKA and THA based on a comparison of international register data.
Orthopadie (Heidelb). 2024;
Doi: 10.1007/s00132-024-04513-7
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2023
Originalarbeit (Zeitschrift)
** Fölsch, C; Preu, S; Ulloa, CAF; Kühn, KD; Rickert, M; Jahnke, A
Palmitic acid coating of allogeneic cancellous bone for local antibiotic treatment: A porcine impaction bone grafting model.
J Orthop. 2023; 35: 24-30.
Doi: 10.1016/j.jor.2022.10.013
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** Fölsch, C; Ulloa, CAF; Harz, T; Schirmer, J; Glameanu, C; Scherberich, J; Krombach, G; Rickert, M; Martin, JR; Kühn, KD; Jahnke, A
Micromotion measurement at the interfaces of cemented tibial endoprosthetic replacements: A new standardized in vitro model using open-cell rigid foam.
Med Eng Phys. 2023; 119: 104027
Doi: 10.1016/j.medengphy.2023.104027
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** Humez, M; Domann, E; Thormann, KM; Fölsch, C; Strathausen, R; Vogt, S; Alt, V; Kühn, KD
Daptomycin-Impregnated PMMA Cement against Vancomycin-Resistant Germs: Dosage, Handling, Elution, Mechanical Stability, and Effectiveness.
Antibiotics (Basel). 2023; 12(11):
Doi: 10.3390/antibiotics12111567
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** Krampitz, B; Steiner, J; Trampuz, A; Kühn, KD
Voriconazole Admixed with PMMA-Impact on Mechanical Properties and Efficacy.
ANTIBIOTICS-BASEL. 2023; 12(5):
Doi: 10.3390/antibiotics12050848
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Übersichtsarbeit
** Berberich, C; Kühn, KD; Alt, V
[Bone cement as a local antibiotic carrier].
Orthopadie (Heidelb). 2023; 52(12):981-991
Doi: 10.1007/s00132-023-04447-6
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** Humez, M; Fröschen, FS; Wirtz, DC; Kühn, KD
[The third-generation modern cementing technique in hip and knee arthroplasty].
Orthopadie (Heidelb). 2023;
Doi: 10.1007/s00132-023-04446-7
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** Paul, C; Kühn, KD
[Chemical and physical properties of PMMA bone cements].
Orthopadie (Heidelb). 2023;
Doi: 10.1007/s00132-023-04445-8
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** Paul, C; Steinhauser, E; Kühn, KD
[Processing properties and viscosities of PMMA bone cements].
Orthopadie (Heidelb). 2023;
Doi: 10.1007/s00132-023-04450-x
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Editorial
** Kühn, KD; von Lewinski, G
PMMA Bone Cement-Part 1
ORTHOPADIE. 2023; 52(12): 941-942.
Doi: 10.1007/s00132-023-04456-5
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2022
Originalarbeit (Zeitschrift)
** Citak, M; Luck, S; Linke, P; Gehrke, T; Kühn, KD
[Manual addition of antibiotics to industrial bone cement mixes : Investigations of the dry mix in the cement cartridge during manual admixture to polymer-active substance mixtures].
Orthopade. 2022; 51(1):44-51
Doi: 10.1007/s00132-021-04115-7
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2021
Originalarbeit (Zeitschrift)
** Hetzmannseder, S; Chang, Y; Kittinger, C; Kühn, KD
Properties of Orthopaedic Cements Biomechanically Little Affected by Exceptional Use of Liquid Antibiotics
ORTHOP SURG. 2021;
Doi: 10.1111/os.12911
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** Kaiser, D; Zimmerli, N; Hartmann, R; Bachmann, E; Kühn, KD; Meyer, DC
Systematic Biomechanical Analysis of Prerequisites for Reliable Intraoperative Bonding of Polymethylmethacrylate Bone Cement in Preexisting Cement in Revision Arthroplasty.
ORTHOPEDICS. 2021; 44(1): e55-e60-e55-e60.
Doi: 10.3928/01477447-20201007-05
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** Labmayr, V; Lerchbaumer, MH; Kuehn, KD; Kittinger, C; Amerstorfer, F; Leithner, A; Glehr, M
Comparison of elution characteristics and mechanical properties of acrylic bone cements with and without superficial vancomycin coating (SVC) in the late phase of polymerization.
Orthop Traumatol Surg Res. 2021; 107(4): 102908
Doi: 10.1016/j.otsr.2021.102908
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2020
Originalarbeit (Zeitschrift)
** Ferlic, PW; Liebensteiner, M; Nogler, M; Weinberg, AM; Kühn, KD; Coraça-Huber, D
Increased Staphylococcus aureus Biofilm Formation on Biodegradable Poly(3-Hydroxybutyrate)-Implants Compared with Conventional Orthopedic Implants: An In Vitro Analysis.
J Orthop Trauma. 2020; 34(4):210-215
Doi: 10.1097/BOT.0000000000001674
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** Ferlic, PW; Nogler, M; Weinberg, AM; Kühn, KD; Liebensteiner, M; Coraça-Huber, DC
Material modifications enhancing the antibacterial properties of two biodegradable poly(3-hydroxybutyrate) implants.
Biomed Mater. 2020; 16(1):015030
Doi: 10.1088/1748-605X/abbec6
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** Schmid, M; Steiner, O; Fasshold, L; Goessler, W; Holl, AM; Kühn, KD
The stability of carbapenems before and after admixture to PMMA-cement used for replacement surgery caused by Gram-negative bacteria.
Eur J Med Res. 2020; 25(1):34-34
Doi: 10.1186/s40001-020-00428-z
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2019
Originalarbeit (Zeitschrift)
** Abdelaziz, H; von Förster, G; Kühn, KD; Gehrke, T; Citak, M
Minimum 5 years' follow-up after gentamicin- and clindamycin-loaded PMMA cement in total joint arthroplasty.
J Med Microbiol. 2019; 68(3):475-479
Doi: 10.1099/jmm.0.000895
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2018
Übersichtsarbeit
** Coraça-Huber, DC; Nogler, M; Kühn, KD
Potential of allogeneic bone grafts as antibiotic carriers : Effect of different preparation processes on efficacy].
ORTHOPADE. 2018; 47(1): 30-38.
Doi: 10.1007/s00132-017-3507-2
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** Kühn, KD; Berberich, C; Bösebeck, H
Bone substitute materials as local drug carriers : Current status of substitutes of various origins].
ORTHOPADE. 2018; 47(1): 10-23.
Doi: 10.1007/s00132-017-3505-4
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2017
Originalarbeit (Zeitschrift)
** Amerstorfer, F; Fischerauer, S; Sadoghi, P; Schwantzer, G; Kuehn, KD; Leithner, A; Glehr, M
Superficial Vancomycin Coating of Bone Cement in Orthopedic Revision Surgery: A Safe Technique to Enhance Local Antibiotic Concentrations.
J Arthroplasty. 2017; 32(5):1618-1624
Doi: 10.1016/j.arth.2016.11.042
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** Clauss, M; Laschkolnig, E; Graf, S; Kühn, KD
Influence of Sonication on Bacterial Regrowth from Antibiotic Loaded PMMA Scaffolds - An In-vitro Study.
J Bone Jt Infect. 2017; 2(4):213-217
Doi: 10.7150/jbji.22382
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Übersichtsarbeit
** Kühn, KD; Renz, N; Trampuz, A
[Local antibiotic therapy].
Unfallchirurg. 2017; 120(7):561-572
Doi: 10.1007/s00113-017-0372-8
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2016
Originalarbeit (Zeitschrift)
** Coraça-Huber, DC; Ammann, CG; Nogler, M; Fille, M; Frommelt, L; Kühn, KD; Fölsch, C
Lyophilized allogeneic bone tissue as an antibiotic carrier.
Cell Tissue Bank. 2016; 17(4):629-642
Doi: 10.1007/s10561-016-9582-5
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** Fölsch, C; Federmann, M; Lakemeier, S; Kuehn, KD; Kittinger, C; Kerwat, M; Fuchs-Winkelmann, S; Paletta, JR; Roessler, PP
Systemic antibiotic therapy does not significantly improve outcome in a rat model of implant-associated osteomyelitis induced by Methicillin susceptible Staphylococcus aureus.
Arch Orthop Trauma Surg. 2016; 136(4):585-592
Doi: 10.1007/s00402-016-2419-7
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2015
Originalarbeit (Zeitschrift)
** Coraca-Huber, DC; Wurm, A; Fille, M; Hausdorfer, J; Nogler, M; Vogt, S; Kuhn, KD
Antibiotic-loaded calcium carbonate/calcium sulfate granules as co-adjuvant for bone grafting
J MATER SCI-MATER M. 2015; 26(1): UNSP 19
Doi: 10.1007/s10856-014-5344-8
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** Fölsch, C; Federmann, M; Kuehn, KD; Kittinger, C; Kogler, S; Zarfel, G; Kerwat, M; Braun, S; Fuchs-Winkelmann, S; Paletta, JR; Roessler, PP
Coating with a novel gentamicinpalmitate formulation prevents implant-associated osteomyelitis induced by methicillin-susceptible Staphylococcus aureus in a rat model.
Int Orthop. 2015; 39(5):981-988
Doi: 10.1007/s00264-014-2582-9
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** Kühn, KD; Höntzsch, D
Augmentation with PMMA cement].
Unfallchirurg. 2015; 118(9):737-748
Doi: 10.1007/s00113-015-0059-y
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** Obermeier, A; Schneider, J; Föhr, P; Wehner, S; Kühn, KD; Stemberger, A; Schieker, M; Burgkart, R
In vitro evaluation of novel antimicrobial coatings for surgical sutures using octenidine.
BMC Microbiol. 2015; 15(4):186-186
Doi: 10.1186/s12866-015-0523-4
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2014
Originalarbeit (Zeitschrift)
** Coraça-Huber, D; Hausdorfer, J; Fille, M; Nogler, M; Kühn, KD
Calcium carbonate powder containing gentamicin for mixing with bone grafts.
Orthopedics. 2014; 37(8):e669-e672
Doi: 10.3928/01477447-20140728-50
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** Coraça-Huber, DC; Putzer, D; Fille, M; Hausdorfer, J; Nogler, M; Kühn, KD
Gentamicin palmitate as a new antibiotic formulation for mixing with bone tissue and local release.
Cell Tissue Bank. 2014; 15(1):139-144
Doi: 10.1007/s10561-013-9384-y
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** Coraça-Huber, DC; Wurm, A; Fille, M; Hausdorfer, J; Nogler, M; Kühn, KD
Effect of freezing on the release rate of gentamicin palmitate and gentamicin sulfate from bone tissue.
J Orthop Res. 2014; 32(6):842-847
Doi: 10.1002/jor.22602
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** Jelecevic, J; Maidanjuk, S; Leithner, A; Loewe, K; Kuehn, KD
Methyl methacrylate levels in orthopedic surgery: comparison of two conventional vacuum mixing systems.
Ann Occup Hyg. 2014; 58(4):493-500
Doi: 10.1093/annhyg/meu001
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2013
Originalarbeit (Zeitschrift)
** Köster, U; Jaeger, R; Bardts, M; Wahnes, C; Büchner, H; Kühn, KD; Vogt, S
Creep and fatigue behavior of a novel 2-component paste-like formulation of acrylic bone cements.
J Mater Sci Mater Med. 2013; 24(6):1395-1406
Doi: 10.1007/s10856-013-4909-2
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2012
Originalarbeit (Zeitschrift)
** Obermeier, A; Matl, FD; Schwabe, J; Zimmermann, A; Kühn, KD; Lakemeier, S; von Eisenhart-Rothe, R; Stemberger, A; Burgkart, R
Novel fatty acid gentamicin salts as slow-release drug carrier systems for anti-infective protection of vascular biomaterials.
J Mater Sci Mater Med. 2012; 23(7):1675-1683
Doi: 10.1007/s10856-012-4631-5
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2011
Originalarbeit (Zeitschrift)
** Kittinger, C; Marth, E; Windhager, R; Weinberg, AM; Zarfel, G; Baumert, R; Felisch, S; Kuehn, KD
Antimicrobial activity of gentamicin palmitate against high concentrations of Staphylococcus aureus.
J Mater Sci Mater Med. 2011; 22(6):1447-1453
Doi: 10.1007/s10856-011-4333-4
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2009
Originalarbeit (Zeitschrift)
** Matl, FD; Zlotnyk, J; Obermeier, A; Friess, W; Vogt, S; Büchner, H; Schnabelrauch, H; Stemberger, A; Kühn, KD
New anti-infective coatings of surgical sutures based on a combination of antiseptics and fatty acids.
J Biomater Sci Polym Ed. 2009; 20(10):1439-1449
Doi: 10.1163/092050609X12457418973107
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2008
Originalarbeit (Zeitschrift)
** Kühn, KD; Weber, C; Kreis, S; Holzgrabe, U
Evaluation of the stability of gentamicin in different antibiotic carriers using a validated MEKC method.
J Pharm Biomed Anal. 2008; 48(3):612-618
Doi: 10.1016/j.jpba.2008.05.041
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** Matl, FD; Obermeier, A; Repmann, S; Friess, W; Stemberger, A; Kuehn, KD
New anti-infective coatings of medical implants.
Antimicrob Agents Chemother. 2008; 52(6):1957-1963
Doi: 10.1128/AAC.01438-07
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2007
Originalarbeit (Zeitschrift)
** Teller, M; Gopp, U; Neumann, HG; Kühn, KD
Release of gentamicin from bone regenerative materials: an in vitro study.
J Biomed Mater Res B Appl Biomater. 2007; 81(1):23-29
Doi: 10.1002/jbm.b.30631
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2005
Übersichtsarbeit
** Kuehn, KD; Ege, W; Gopp, U
Acrylic bone cements: composition and properties.
Orthop Clin North Am. 2005; 36(1):17-28
Doi: 10.1016/j.ocl.2004.06.010
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** Kuehn, KD; Ege, W; Gopp, U
Acrylic bone cements: mechanical and physical properties.
Orthop Clin North Am. 2005; 36(1):29-39
Doi: 10.1016/j.ocl.2004.06.011
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2003
Originalarbeit (Zeitschrift)
** Jahnke, M; Kühn, KD
Use of the hazard analysis and critical control points (HACCP) risk assessment on a medical device for parenteral application.
PDA J Pharm Sci Technol. 2003; 57(1):32-42
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Übersichtsarbeit
** Breusch, SJ; Kühn, KD
Bone cements based on polymethylmethacrylate.
Orthopade. 2003; 32(1):41-50
Doi: 10.1007/s00132-002-0411-0
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** Schnürer, SM; Gopp, U; Kühn, KD; Breusch, SJ
Bone substitutes.
Orthopade. 2003; 32(1):2-10
Doi: 10.1007/s00132-002-0407-9
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