Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Sinner Frank Michael |

** = Publikationen gelistet in SCI/SSCI/Pubmed

2024

Originalarbeit (Zeitschrift)

** Monedeiro, F; Ehall, B; Tiffner, K; Eberl, A; Svehlikova, E; Prietl, B; Pfeifer, V; Senekowitsch, J; Remm, A; Rebane, A; Magnes, C; Pieber, T; Sinner, F; Birngruber, T Characterization of Inflammatory Mediators and Metabolome in Interstitial Fluid Collected with Dermal Open Flow Microperfusion before and at the End of Dupilumab Treatment in Atopic Dermatitis.
J Proteome Res. 2024; Doi: 10.1021/acs.jproteome.4c00153 [OPEN ACCESS]
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** Tiffner, KI; Ramezanli, T; Boulgaropoulos, B; Birngruber, T; Bodenlenz, M; Lackner, BC; Raml, R; Jiang, Y; Raney, SG; Sinner, F Cutaneous pharmacokinetics-based bioequivalence: A clinical dermal open flow microperfusion verification study using lidocaine and prilocaine combination topical products
EUR J PHARM SCI. 2024; 200: 106827 Doi: 10.1016/j.ejps.2024.106827
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2023

Abstract (Zeitschrift)

** Monedeiro, F; Ehall, B; Prugger, EM; Zügner, E; Svehlikova, E; Pieber, T; Tiffner, K; Magnes, C; Sinner, F; Birngruber, T Interstitial fluid metabolomics shows dupilumab effects in the treatment of atopic dermatitis.
J INVEST DERMATOL. 2023; 143(11):S352-S352.-5th Inflammatory Skin Disease Summit (ISDS); NOV 15-18, 2023; Vienna, AUSTRIA. [Poster]
Web of Science

 

** Tiffner, K; Ehall, B; Eberl, A; Bodenlenz, M; Pircher, T; Birngruber, T; Sinner, F; Svehlikova, E; Pieber, T Dermal open flow microperfusion (dOFM) to monitor local tissue response after dupilumab treatment in lesional and non-lesional skin of atopic dermatitis patients
J INVEST DERMATOL. 2023; 143(11):S348-S348.-5th Inflammatory Skin Disease Summit (ISDS); NOV 15-18, 2023; Vienna, AUSTRIA. [Poster]
Web of Science

 

2022

Originalarbeit (Zeitschrift)

** Kopanz, J; Mader, JK; Donsa, K; Libiseller, A; Aberer, F; Pandis, M; Reinisch-Gratzer, J; Ambrosch, G; Lackner, B; Truskaller, T; Sinner, FM; Pieber, TR; Lichtenegger, KM Digital algorithm-guided insulin therapy in home healthcare for elderly persons with type 2 diabetes: A proof-of-concept study.
Frontiers in clinical diabetes and healthcare. 2022; 3: Doi: 10.3389/fcdhc.2022.986672 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Übersichtsarbeit

** Birngruber, T; Tiffner, KI; Mautner, SI; Sinner, FM Dermal open flow microperfusion for PK-based clinical bioequivalence studies of topical drug products.
Front Pharmacol. 2022; 13: 1061178 Doi: 10.3389/fphar.2022.1061178 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Abstract (Zeitschrift)

** Lichtenegger, K; Scholle, L; Kopanz, J; Libiseller, A; Reinisch-Gratzer, J; Ambrosch, G; Donsa, K; Sinner, F; Pieber, T; Klampfl-Kenny, M; Mader, J Diabetes prevalence and quality of diabetes management before, during and after the implementation of digital decision support for mobile care and support
WIEN KLIN WOCHENSCHR. 2022; 134(SUPPL 4):248-248. [Poster]
Web of Science

 

** Shukla, S; Ramezanli, T; Rantou, E; Tiffner, K; Birngruber, T; Sinner, F; Raney, S QUANTITATIVE DISCRIMINATION OF CUTANEOUS PHARMACOKINETIC PROFILES FOR TOPICAL DRUG PRODUCTS.
CLIN PHARMACOL THER. ASCPT Online Annual Meeting. 2022; 111: S47-S47.-American Society for Clinical Pharmacology and Therapeutics Annual Meeting; MAR 16-18, 2022; Virtuell. [Oral Communication]
Web of Science

 

2021

Originalarbeit (Zeitschrift)

** Hummer, J; Schwingenschuh, S; Raml, R; Boulgaropoulos, B; Schwagerle, G; Augustin, T; Sinner, F; Birngruber, T OFM-recirculation and OFM-suction: advanced in-vivo open flow microperfusion (OFM) methods for direct and absolute quantification of albumin in interstitial fluid.
BIOMED PHYS ENG EXPR. 2021; 6(6): 065031-065031. Doi: 10.1088/2057-1976/abc3a7 [OPEN ACCESS]
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** Kopanz, J; Lichtenegger, KM; Koenig, C; Libiseller, A; Mader, JK; Donsa, K; Truskaller, T; Bauer, N; Hahn, B; Sendlhofer, G; Beck, P; Höll, B; Sinner, F; Feichtner, F; Pieber, TR Electronic Diabetes Management System Replaces Paper Insulin Chart: Improved Quality in Diabetes Inpatient Care Processes Due to Digitalization.
J Diabetes Sci Technol. 2021; 15(2):222-230 Doi: 10.1177/1932296820957043 [OPEN ACCESS]
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** Schroeder, S; Hofer, SJ; Zimmermann, A; Pechlaner, R; Dammbrueck, C; Pendl, T; Marcello, GM; Pogatschnigg, V; Bergmann, M; Müller, M; Gschiel, V; Ristic, S; Tadic, J; Iwata, K; Richter, G; Farzi, A; Üçal, M; Schäfer, U; Poglitsch, M; Royer, P; Mekis, R; Agreiter, M; Tölle, RC; Sótonyi, P; Willeit, J; Mairhofer, B; Niederkofler, H; Pallhuber, I; Rungger, G; Tilg, H; Defrancesco, M; Marksteiner, J; Sinner, F; Magnes, C; Pieber, TR; Holzer, P; Kroemer, G; Carmona-Gutierrez, D; Scorrano, L; Dengjel, J; Madl, T; Sedej, S; Sigrist, SJ; Rácz, B; Kiechl, S; Eisenberg, T; Madeo, F Dietary spermidine improves cognitive function.
Cell Rep. 2021; 35(2):108985-108985 Doi: 10.1016/j.celrep.2021.108985 [OPEN ACCESS]
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** Tiffner, KI; Kanfer, I; Augustin, T; Raml, R; Raney, SG; Sinner, F Comparative in vitro release testing (IVRT) of acyclovir products
INT J PHARMACEUT. 2021; 609: 121186 Doi: 10.1016/j.ijpharm.2021.121186
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2020

Originalarbeit (Zeitschrift)

** Bodenlenz, M; Augustin, T; Birngruber, T; Tiffner, KI; Boulgaropoulos, B; Schwingenschuh, S; Raney, SG; Rantou, E; Sinner, F Variability of Skin Pharmacokinetic Data: Insights from a Topical Bioequivalence Study Using Dermal Open Flow Microperfusion.
Pharm Res. 2020; 37(10):204-204 Doi: 10.1007/s11095-020-02920-x [OPEN ACCESS]
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** Eirefelt, S; Hummer, J; Basse, LH; Bertelsen, M; Johansson, F; Birngruber, T; Sinner, F; Larsen, J; Nielsen, SF; Lambert, M Evaluating Dermal Pharmacokinetics and Pharmacodymanic Effect of Soft Topical PDE4 Inhibitors: Open Flow Microperfusion and Skin Biopsies.
Pharm Res. 2020; 37(12): 243-243. Doi: 10.1007/s11095-020-02962-1
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** Libiseller, A; Kopanz, J; Lichtenegger, KM; Mader, JK; Truskaller, T; Lackner, B; Aberer, F; Pandis, M; Reinisch-Gratzer, J; Ambrosch, GC; Sinner, F; Pieber, TR; Donsa, K Study protocol for assessing the user acceptance, safety and efficacy of a tablet-based workflow and decision support system with incorporated basal insulin algorithm for glycaemic management in participants with type 2 diabetes receiving home health care: A single-centre, open-label, uncontrolled proof-of-concept study.
Contemp Clin Trials Commun. 2020; 19(10):100620-100620 Doi: 10.1016/j.conctc.2020.100620 [OPEN ACCESS]
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Korrektur

** Stekovic, S; Hofer, SJ; Tripolt, N; Aon, MA; Royer, P; Pein, L; Stadler, JT; Pendl, T; Prietl, B; Url, J; Schroeder, S; Tadic, J; Eisenberg, T; Magnes, C; Stumpe, M; Zuegner, E; Bordag, N; Riedl, R; Schmidt, A; Kolesnik, E; Verheyen, N; Springer, A; Madl, T; Sinner, F; de Cabo, R; Kroemer, G; Obermayer-Pietsch, B; Dengjel, J; Sourij, H; Pieber, TR; Madeo, F Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans.
Cell Metab. 2020; 31(4):878-881 Doi: 10.1016/j.cmet.2020.02.011 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Kopanz, J; Libiseller, A; Lichtenegger, K; Donsa, K; Truskaller, T; Lackner, B; Aberer, F; Pandis, M; Reinisch-Gratzer, J; Ambrosch, G; Sinner, F; Pieber, T; Mader, J A DIGITAL WORKFLOW AND DECISION SUPPORT SYSTEM TO PREVENT DIABETES-RELATED ACUTE HOSPITAL ADMISSIONS AND INPATIENT STAYS (THE GLUCOTAB@MOBILECARE STUDY).
DIABETES TECHNOL THE. The Official Journal of ATTD: Advanced Technologies & Treatments for Diabetes Conference. 2020; 22: A110-A110.-Advanced Technologies & Treatments for Diabetes Conference; FEB 19-20, 2020; Madrid, SPAIN. [Poster]
Web of Science

 

** Kopanz, J; Libiseller, A; Lichtenegger, K; Donsa, K; Truskaller, T; Lackner, B; Aberer, F; Pandis, M; Reinisch-Gratzer, J; Ambrosch, G; Sinner, F; Pieber, T; Mader, J EFFECTIVE, SAFE AND USER-ACCEPTED BASAL-INSULIN THERAPY IN ELDERLY PATIENTS WITH TYPE 2 DIABETES RECEIVING DIGITALY ASSISTED DOMICILIARY NURSING CARE - THE GLUCOTAB@MOBILECARE STUDY.
DIABETES TECHNOL THE. The Official Journal of ATTD: Advanced Technologies & Treatments for Diabetes Conference. 2020; 22: A109-A110.-Advanced Technologies & Treatments for Diabetes Conference; FEB 19-20, 2020; Madrid, SPAIN. [Poster]
Web of Science

 

** Lichtenegger, K; Kopanz, J; Libiseller, A; Mader, J; Donsa, K; Truskaller, T; Bauer, N; Hahn, B; Sendlhofer, G; Beck, P; Feichtner, F; Sinner, F; Pieber, T IMPLEMENTATION OF A DIGITAL WORKFLOW AND DECISION SUPPORT SYSTEM CONFIRMS EFFICACY AND USER-SATISFACTION OF ROUTINE DIABETES CARE IN INPATIENTS WITH TYPE 2 DIABETES.
DIABETES TECHNOL THE. The Official Journal of ATTD: Advanced Technologies & Treatments for Diabetes Conference. 2020; 22: A111-A111.-Advanced Technologies & Treatments for Diabetes Conference; FEB 19-20, 2020; Madrid, SPAIN. [Poster]
Web of Science

 

2019

Originalarbeit (Zeitschrift)

** Altendorfer-Kroath, T; Schimek, D; Eberl, A; Rauter, G; Ratzer, M; Raml, R; Sinner, F; Birngruber, T Comparison of cerebral Open Flow Microperfusion and Microdialysis when sampling small lipophilic and small hydrophilic substances.
J Neurosci Methods. 2019; 311(4):394-401 Doi: 10.1016/j.jneumeth.2018.09.024
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** Altendorfer-Kroath, T; Schwingenschuh, S; Schøndorff, PK; Heschel, M; Sinner, F; Birngruber, T Insulin Distribution in Human Adipose Tissue via a Novel Insulin Infusion Catheter.
Diabetes Technol Ther. 2019; 21(12):740-744 Doi: 10.1089/dia.2019.0195
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** Carmona-Gutierrez, D; Zimmermann, A; Kainz, K; Pietrocola, F; Chen, G; Maglioni, S; Schiavi, A; Nah, J; Mertel, S; Beuschel, CB; Castoldi, F; Sica, V; Trausinger, G; Raml, R; Sommer, C; Schroeder, S; Hofer, SJ; Bauer, MA; Pendl, T; Tadic, J; Dammbrueck, C; Hu, Z; Ruckenstuhl, C; Eisenberg, T; Durand, S; Bossut, N; Aprahamian, F; Abdellatif, M; Sedej, S; Enot, DP; Wolinski, H; Dengjel, J; Kepp, O; Magnes, C; Sinner, F; Pieber, TR; Sadoshima, J; Ventura, N; Sigrist, SJ; Kroemer, G; Madeo, F The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species.
Nat Commun. 2019; 10(1):651-651 Doi: 10.1038/s41467-019-08555-w [OPEN ACCESS]
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** Pipper, C; Bordag, N; Reiter, B; Economides, K; Florian, P; Birngruber, T; Sinner, F; Bodenlenz, M; Eberl, A LC/MS/MS analyses of open-flow microperfusion samples quantify eicosanoids in a rat model of skin inflammation.
J Lipid Res. 2019; 60(4):758-766 Doi: 10.1194/jlr.M087221 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Stekovic, S; Hofer, SJ; Tripolt, N; Aon, MA; Royer, P; Pein, L; Stadler, JT; Pendl, T; Prietl, B; Url, J; Schroeder, S; Tadic, J; Eisenberg, T; Magnes, C; Stumpe, M; Zuegner, E; Bordag, N; Riedl, R; Schmidt, A; Kolesnik, E; Verheyen, N; Springer, A; Madl, T; Sinner, F; de Cabo, R; Kroemer, G; Obermayer-Pietsch, B; Dengjel, J; Sourij, H; Pieber, TR; Madeo, F Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans.
Cell Metab. 2019; 30(3):462-476 Doi: 10.1016/j.cmet.2019.07.016 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Donsa, K; Stampfer, P; Truskaller, T; Kopanz, J; Konig, C; Lichtenegger, K; Mrak, P; Pinter, G; Schippinger, W; Sinner, F Development of an innovative eHealth System for comprehensive Quality Assurance and Therapy Support in Austrian Institutions of Acute Geriatrics and Remobilization - Presentation of a user-centered Development Process
Z GERONTOL GERIATR. 2019; 52: S158-S158. [Poster]
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** Kopanz, J; Libiseller, A; Lichtenegger, KM; Donsa, K; Truskaller, T; Lackner, B; Aberer, F; Pandis, M; Reinisch-Gratzer, J; Ambrosch, GC; Sinner, F; Pieber, TR; Mader, JK GlucoTab@MobileCare - Clinical Endpoints of a Proof-of-Concept Study of a Digital Workflow and Decision Support System for Diabetes Management in Mobile Home Health Care
WIEN KLIN WOCHENSCHR. 2019; 131(SUPPL 5):S466-S467. [Oral Communication]
Web of Science

 

** Kopanz, J; Lichtenegger, KM; Konig, C; Feichtner, F; Libiseller, A; Mader, JK; Donsa, K; Sendlhofer, G; Sinner, F; Pieber, TR Does the implementation of an electronic workflow support system improve quality of routine diabetes care in inpatients with type 2 diabetes?.
DIABETOLOGIA. 2019; 62: S395-S395.-55th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD); SEP 16-20, 2019; Barcelona, SPAIN. [Poster]
Web of Science

 

** Kopanz, J; Lichtenegger, KM; Konig, C; Libiseller, A; Mader, JK; Donsa, K; Truskaller, T; Bauer, N; Hahn, B; Sendlhofer, G; Beck, P; Sinner, F; Feichtner, F; Pieber, TR The GlucoTab® System in Routine Use to Support Diabetes Management for Patients with Diabetes Mellitus Type 2 in a regional Hospital.
WIEN KLIN WOCHENSCHR. 2019; 131(SUPPL 5):S467-S467. [Poster]
Web of Science

 

** Libiseller, A; Kopanz, J; Lichtenegger, KM; Donsa, K; Truskaller, T; Lackner, B; Aberer, F; Pandis, M; Reinisch-Gratzer, J; Ambrosch, GC; Sinner, F; Pieber, TR; Mader, JK GlucoTab@MobileCare - The Potential of Decision Support to Reduce Hospital Admissions and inpatient Admissions
WIEN KLIN WOCHENSCHR. 2019; 131(SUPPL 5):S469-S469. [Poster]
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2018

Originalarbeit (Zeitschrift)

** Meyer, M; Donsa, K; Truskaller, T; Frohner, M; Pohn, B; Felfernig, A; Sinner, F; Pieber, T Development of a Protocol for Automated Glucose Measurement Transmission Used in Clinical Decision Support Systems Based on the Continua Design Guidelines.
Stud Health Technol Inform. 2018; 248(4):132-139
PubMed

 

** Schimek, D; Raml, R; Francesconi, KA; Bodenlenz, M; Sinner, F Quantification of acyclovir in dermal interstitial fluid and human serum by ultra-high-performance liquid-high-resolution tandem mass spectrometry for topical bioequivalence evaluation.
Biomed Chromatogr. 2018; 32(6):e4194-e4194 Doi: 10.1002/bmc.4194
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** Tiffner, KI; Kanfer, I; Augustin, T; Raml, R; Raney, SG; Sinner, F A comprehensive approach to qualify and validate the essential parameters of an in vitro release test (IVRT) method for acyclovir cream, 5.
Int J Pharm. 2018; 535(1-2): 217-227. Doi: 10.1016/j.ijpharm.2017.09.049 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Bodenlenz, M; Birngruber, T; Prietl, B; Economides, K; Florian, P; Subramaniam, A; Hultsch, T; Raml, R; Eberl, A; Mautner, S; Sinner, F Characterization of the psoriasis-like inflammation in the imiquimod rat model using the clinical method of dermal open flow microperfusion
EXP DERMATOL. 2018; 27: 10-10.-3rd Inflammatory Skin Disease Summit; DEC 12-15, 2018; Vienna, AUSTRIA. [Poster]
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2017

Originalarbeit (Zeitschrift)

** Bode, GH; Coué, G; Freese, C; Pickl, KE; Sanchez-Purrà, M; Albaiges, B; Borrós, S; van Winden, EC; Tziveleka, LA; Sideratou, Z; Engbersen, JFJ; Singh, S; Albrecht, K; Groll, J; Möller, M; Pötgens, AJG; Schmitz, C; Fröhlich, E; Grandfils, C; Sinner, FM; Kirkpatrick, CJ; Steinbusch, HWM; Frank, HG; Unger, RE; Martinez-Martinez, P An in vitro and in vivo study of peptide-functionalized nanoparticles for brain targeting: The importance of selective blood-brain barrier uptake.
Nanomedicine. 2017; 13(3):1289-1300 Doi: 10.1016/j.nano.2016.11.009
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** Bodenlenz, M; Tiffner, KI; Raml, R; Augustin, T; Dragatin, C; Birngruber, T; Schimek, D; Schwagerle, G; Pieber, TR; Raney, SG; Kanfer, I; Sinner, F Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence.
Clin Pharmacokinet. 2017; 56(1):91-98 Doi: 10.1007/s40262-016-0442-z [OPEN ACCESS]
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** Kolbinger, F; Loesche, C; Valentin, MA; Jiang, X; Cheng, Y; Jarvis, P; Peters, T; Calonder, C; Bruin, G; Polus, F; Aigner, B; Lee, DM; Bodenlenz, M; Sinner, F; Pieber, TR; Patel, DD β-Defensin 2 is a responsive biomarker of IL-17A-driven skin pathology in patients with psoriasis.
J Allergy Clin Immunol. 2017; 139(3):923-932 Doi: 10.1016/j.jaci.2016.06.038 [OPEN ACCESS]
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** Rumpler, M; Mader, JK; Fischer, JP; Thar, R; Granger, JM; Deliane, F; Klimant, I; Aberer, F; Sinner, F; Pieber, TR; Hajnsek, M First application of a transcutaneous optical single-port glucose monitoring device in patients with type 1 diabetes mellitus.
Biosens Bioelectron. 2017; 88:240-248 Doi: 10.1016/j.bios.2016.08.039
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** Schwingenschuh, S; Scharfetter, H; Martinsen, ØG; Boulgaropoulos, B; Augustin, T; Tiffner, KI; Dragatin, C; Raml, R; Hoefferer, C; Prandl, EC; Sinner, F; Hajnsek, M Assessment of skin permeability to topically applied drugs by skin impedance and admittance.
Physiol Meas. 2017; 38(11):N138-N150 Doi: 10.1088/1361-6579/aa904e
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** Tiffner, K; Boulgaropoulos, B; Höfferer, C; Birngruber, T; Porksen, N; Linnebjerg, H; Garhyan, P; Lam, ECQ; Knadler, MP; Pieber, TR; Sinner, F Quantification of Basal Insulin Peglispro and Human Insulin in Adipose Tissue Interstitial Fluid by Open-Flow Microperfusion.
Diabetes Technol Ther. 2017; 19(5):305-314 Doi: 10.1089/dia.2016.0384
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Korrektur

** Bodenlenz, M; Tiffner, KI; Raml, R; Augustin, T; Dragatin, C; Birngruber, T; Schimek, D; Schwagerle, G; Pieber, TR; Raney, SG; Kanfer, I; Sinner, F Erratum to: Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence.
Clin Pharmacokinet. 2017; 56(1):99-99 Doi: 10.1007/s40262-016-0487-z [OPEN ACCESS]
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Abstract (Zeitschrift)

** Birngruber, T; Prietl, B; Bodenlenz, M; Florian, P; Subramaniam, A; Kainz, S; Rauter, G; Pieber, TR; Sinner, F Continuous sampling of immune cells in the skin by dermal open flow microperfusion
J INVEST DERMATOL. 2017; 137(10):S275-S275.-47th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR); SEP 27-30, 2017; Salzburg, AUSTRIA. Doi: 10.1016/j.jid.2017.07.684 [Poster]
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** Bodenlenz, M; Prietl, B; Florian, P; Subramaniam, A; Kainz, S; Rauter, G; Pieber, TR; Sinner, F Characterization of the Psoriasis-like Inflammation in the Imiquimod Rat Model using Dermal Open Flow Microperfusion
J INVEST DERMATOL. 2017; 137(10):S278-S278.-47th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR); SEP 27-30, 2017; Salzburg, AUSTRIA. Doi: 10.1016/j.jid.2017.07.698 [Poster]
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** Bucher, N; Adamczak, J; Fahrngruber, H; Reisenegger, P; Stutz, A; Wolff-Winiski, B; Kamolz, L; Sinner, F; Birngruber, T Porcine wound model of persistent inflammation in chronic wounds
J INVEST DERMATOL. 2017; 137(10):S312-S312.-47th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR); SEP 27-30, 2017; Salzburg, AUSTRIA. Doi: 10.1016/j.jid.2017.07.373 [Oral Communication]
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2016

Originalarbeit (Zeitschrift)

** Bodenlenz, M; Dragatin, C; Liebenberger, L; Tschapeller, B; Boulgaropoulos, B; Augustin, T; Raml, R; Gatschelhofer, C; Wagner, N; Benkali, K; Rony, F; Pieber, T; Sinner, F Kinetics of Clobetasol-17-Propionate in Psoriatic Lesional and Non-Lesional Skin Assessed by Dermal Open Flow Microperfusion with Time and Space Resolution.
Pharm Res. 2016; 33(9):2229-2238 Doi: 10.1007/s11095-016-1960-y [OPEN ACCESS]
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** Eberl, A; Altendorfer-Kroath, T; Kollmann, D; Birngruber, T; Sinner, F; Raml, R; Magnes, C Determination of (2)H-enrichment of rat brain interstitial fluid and rat plasma by headspace-gas-chromatography - quadrupole-mass-spectrometry.
Anal Biochem. 2016; 509(3):130-134 Doi: 10.1016/j.ab.2016.07.010
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** Narath, SH; Mautner, SI; Svehlikova, E; Schultes, B; Pieber, TR; Sinner, FM; Gander, E; Libiseller, G; Schimek, MG; Sourij, H; Magnes, C An Untargeted Metabolomics Approach to Characterize Short-Term and Long-Term Metabolic Changes after Bariatric Surgery.
PLoS One. 2016; 11(9):e0161425-e0161425 Doi: 10.1371/journal.pone.0161425 [OPEN ACCESS]
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Kurzbericht/Letter

** Dragatin, C; Polus, F; Bodenlenz, M; Calonder, C; Aigner, B; Tiffner, KI; Mader, JK; Ratzer, M; Woessner, R; Pieber, TR; Cheng, Y; Loesche, C; Sinner, F; Bruin, G Secukinumab distributes into dermal interstitial fluid of psoriasis patients as demonstrated by open flow microperfusion.
Exp Dermatol. 2016; 25(2):157-159 Doi: 10.1111/exd.12863 [OPEN ACCESS]
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Übersichtsarbeit

** Birngruber, T; Sinner, F Cerebral open flow microperfusion (cOFM) an innovative interface to brain tissue.
Drug Discov Today Technol. 2016; 20(5): 19-25. Doi: 10.1016/j.ddtec.2016.07.003
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Abstract (Zeitschrift)

** Aberer, F; Hajnsek, M; Rumpler, M; Zenz, S; Puffing, A; Augustin, T; Baumann, P; Sinner, F; Sourijl, H; Pieber, TR; Mader, JK Standardised evaluation of three continuous glucose monitoring systems mimicking real-life conditions.
DIABETOLOGIA. 2016; 59: S411-S412.-52nd Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD); SEP 12-16, 2016; Munich, GERMANY. [Oral Communication]
Web of Science

 

** Loesche, C; Kolbinger, F; Valentin, MA; Jarvis, P; Cheng, Y; Bruin, G; Polus, F; Aigner, B; Bodenlenz, M; Sinner, F; Pieber, TR; Patel, DD beta-defensin-2 (BD-2) responds to a single dose of anti-IL-17A secukinumab in different skin layers of psoriatic patients within days
EXP DERMATOL. .. 2016; 25: 37-38.-2nd Inflammatroy Skin Disease Summit; NOV 16-19, 2016; New York, NY. [Poster]
Web of Science

 

** Mader, JK; Hajnsek, M; Aberer, F; Rumpler, M; Zenz, S; Puffing, A; Elsayed, H; Baumann, P; Sinner, F; Pieber, TR Standardized Assessment of three continuous Glucose Monitoring Systems under realistic Conditions
WIEN KLIN WOCHENSCHR. 2016; 128: S400-S400. [Poster]
Web of Science

 

** Rumpler, M; Hajnsek, M; Mader, JK; Sinner, F; Pieber, TR SPIDIMAN: Clinical Trial of a Single-Port Glucose Sensor on a Commercial Insulin Infusion Set.
DIABETES TECHNOL THE. 2016; 18: A28-A28.-9th International Conference of Advanced Technologies and Treatments for Diabetes (ATTD); FEB 3-6, 2016; Milan, ITALY. [Oral Communication]
Web of Science

 

2015

Originalarbeit (Zeitschrift)

** Bode, GH; Pickl, KE; Sanchez-Purrà, M; Albaiges, B; Borrós, S; Pötgens, AJ; Schmitz, C; Sinner, FM; Losen, M; Steinbusch, HW; Frank, HG; Martinez-Martinez, P; European NanoBioPharmaceutics Research Initiative Detection of Peptide-based nanoparticles in blood plasma by ELISA.
PLoS One. 2015; 10(5):e0126136-e0126136 Doi: 10.1371/journal.pone.0126136 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Braun, RJ; Sommer, C; Leibiger, C; Gentier, RJG; Dumit, VI; Paduch, K; Eisenberg, T; Habernig, L; Trausinger, G; Magnes, C; Pieber, T; Sinner, F; Dengjel, J; van Leeuwen, FW; Kroemer, G; Madeo, F Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin.
Cell Rep. 2015; 10(9):1557-1571 Doi: 10.1016/j.celrep.2015.02.009 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Hajnsek, M; Schiffer, D; Harrich, D; Koller, D; Verient, V; van der Palen, J; Heinzle, A; Binder, B; Sigl, E; Sinner, F; Guebitz, GM An electrochemical sensor for fast detection of wound infection based on myeloperoxidase activity
SENSOR ACTUAT B-CHEM. 2015; 209: 265-274. Doi: 10.1016/j.snb.2014.11.125
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** Höfferer, C; Tutkur, D; Fledelius, C; Brand, CL; Alsted, TJ; Damgaard, J; Nishimura, E; Jeppesen, CB; Mautner, SI; Pieber, TR; Sinner, F Open flow microperfusion: pharmacokinetics of human insulin and insulin detemir in the interstitial fluid of subcutaneous adipose tissue.
Diabetes Obes Metab. 2015; 17(2):121-127 Doi: 10.1111/dom.12394
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** Libiseller, G; Dvorzak, M; Kleb, U; Gander, E; Eisenberg, T; Madeo, F; Neumann, S; Trausinger, G; Sinner, F; Pieber, T; Magnes, C IPO: a tool for automated optimization of XCMS parameters.
BMC Bioinformatics. 2015; 16(5):118-118 Doi: 10.1186/s12859-015-0562-8 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Nacht, B; Larndorfer, C; Sax, S; Borisov, SM; Hajnsek, M; Sinner, F; List-Kratochvil, EJ; Klimant, I Integrated catheter system for continuous glucose measurement and simultaneous insulin infusion.
Biosens Bioelectron. 2015; 64(2):102-110 Doi: 10.1016/j.bios.2014.08.012
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** Raml, R; Ratzer, M; Obermayer-Pietsch, B; Mautner, A; Pieber, TR; Sinner, FM; Magnes, C Quantifying vitamin D and its metabolites by LC/Orbitrap MS
ANAL METHODS-UK. 2015; 7(20): 8961-8966. Doi: 10.1039/c5ay01583a
Web of Science FullText FullText_MUG

 

Abstract (Zeitschrift)

** Rumpler, M; Hajnsek, M; Klimant, I; Sinner, F; Pieber, TR COMPENSATION OF OXYGEN PARTIAL PRESSURE VARIATIONS DURING OPTICAL, ENZYMATIC GLUCOSE SENSING IN ADIPOSE TISSUE
DIABETES TECHNOL THE. . 2015; 17: A89-A89. [Oral Communication]
Web of Science

 

Kommentar

** Braun, RJ; Sommer, C; Leibiger, C; Gentier, RJ; Dumit, VI; Paduch, K; Eisenberg, T; Habernig, L; Trausinger, G; Magnes, C; Pieber, T; Sinner, F; Dengjel, J; Leeuwen, FW; Kroemer, G; Madeo, F Modeling non-hereditary mechanisms of Alzheimer disease during apoptosis in yeast.
Microb Cell. 2015; 2(4): 136-138. Doi: 10.15698/mic2015.04.199 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

2014

Originalarbeit (Zeitschrift)

** Birngruber, T; Ghosh, A; Hochmeister, S; Asslaber, M; Kroath, T; Pieber, TR; Sinner, F Long-term implanted cOFM probe causes minimal tissue reaction in the brain.
PLoS One. 2014; 9(3):e90221-e90221 Doi: 10.1371/journal.pone.0090221 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Birngruber, T; Raml, R; Gladdines, W; Gatschelhofer, C; Gander, E; Ghosh, A; Kroath, T; Gaillard, PJ; Pieber, TR; Sinner, F Enhanced doxorubicin delivery to the brain administered through glutathione PEGylated liposomal doxorubicin (2B3-101) as compared with generic Caelyx,(®)/Doxil(®)--a cerebral open flow microperfusion pilot study.
J Pharm Sci. 2014; 103(7):1945-1948 Doi: 10.1002/jps.23994
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** Eisenberg, T; Schroeder, S; Andryushkova, A; Pendl, T; Küttner, V; Bhukel, A; Mariño, G; Pietrocola, F; Harger, A; Zimmermann, A; Moustafa, T; Sprenger, A; Jany, E; Büttner, S; Carmona-Gutierrez, D; Ruckenstuhl, C; Ring, J; Reichelt, W; Schimmel, K; Leeb, T; Moser, C; Schatz, S; Kamolz, LP; Magnes, C; Sinner, F; Sedej, S; Fröhlich, KU; Juhasz, G; Pieber, TR; Dengjel, J; Sigrist, SJ; Kroemer, G; Madeo, F Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan.
Cell Metab. 2014; 19(3):431-444 Doi: 10.1016/j.cmet.2014.02.010 [OPEN ACCESS]
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** Ghosh, A; Birngruber, T; Sattler, W; Kroath, T; Ratzer, M; Sinner, F; Pieber, TR Assessment of blood-brain barrier function and the neuroinflammatory response in the rat brain by using cerebral open flow microperfusion (cOFM).
PLoS One. 2014; 9(5):e98143-e98143 Doi: 10.1371/journal.pone.0098143 [OPEN ACCESS]
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** Hajnsek, M; Nacht, B; Sax, S; List, EJ; Klimant, I; Sinner, F The single-port concept: combining optical glucose measurement with insulin infusion.
Acta Diabetol. 2014; 51(5):883-886 Doi: 10.1007/s00592-014-0578-y
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** Magnes, C; Fauland, A; Gander, E; Narath, S; Ratzer, M; Eisenberg, T; Madeo, F; Pieber, T; Sinner, F Polyamines in biological samples: rapid and robust quantification by solid-phase extraction online-coupled to liquid chromatography-tandem mass spectrometry.
J Chromatogr A. 2014; 1331(5):44-51 Doi: 10.1016/j.chroma.2013.12.061 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Mariño, G; Pietrocola, F; Eisenberg, T; Kong, Y; Malik, SA; Andryushkova, A; Schroeder, S; Pendl, T; Harger, A; Niso-Santano, M; Zamzami, N; Scoazec, M; Durand, S; Enot, DP; Fernández, ÁF; Martins, I; Kepp, O; Senovilla, L; Bauvy, C; Morselli, E; Vacchelli, E; Bennetzen, M; Magnes, C; Sinner, F; Pieber, T; López-Otín, C; Maiuri, MC; Codogno, P; Andersen, JS; Hill, JA; Madeo, F; Kroemer, G Regulation of autophagy by cytosolic acetyl-coenzyme A.
Mol Cell. 2014; 53(5):710-725 Doi: 10.1016/j.molcel.2014.01.016 [OPEN ACCESS]
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** Millotti, G; Laffleur, F; Perera, G; Vigl, C; Pickl, K; Sinner, F; Bernkop-Schnürch, A In vivo evaluation of thiolated chitosan tablets for oral insulin delivery.
J Pharm Sci. 2014; 103(10):3165-3170 Doi: 10.1002/jps.24102
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** Schroeder, S; Pendl, T; Zimmermann, A; Eisenberg, T; Carmona-Gutierrez, D; Ruckenstuhl, C; Mariño, G; Pietrocola, F; Harger, A; Magnes, C; Sinner, F; Pieber, TR; Dengjel, J; Sigrist, SJ; Kroemer, G; Madeo, F Acetyl-coenzyme A: a metabolic master regulator of autophagy and longevity.
Autophagy. 2014; 10(7):1335-1337 Doi: 10.4161/auto.28919 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Abstract (Zeitschrift)

** Bodenlenz, M; Dragatin, C; Benkali, K; Augustin, T; Hoefferer, C; Martel, P; Rony, F; Pieber, TR; Wagner, N; Sinner, F Topical penetration of clobetasol-17-propionate into psoriatic lesional and non-lesional skin illustrated with time and space resolution by dermal open flow microperfusion
J INVEST DERMATOL. 2014; 134: S38-S38.-44th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR); SEP 10-13, 2014; Copenhagen, DENMARK. [Poster]
Web of Science

 

** Bruin, G; Dragatin, C; Aigner, B; Polus, F; Calonder, C; Froeliger, C; Tiffner, K; Bodenlenz, M; Mader, J; Korsatko, S; Ratzer, M; Pieber, T; Loesche, C; Sinner, F The anti IL-17A IgG1 antibody distributes in dermal interstitial fluid as demonstrated by using dermal open flow microperfusion after a single 300 mg subcutaneous administration; assessment in healthy volunteers and patients with moderate-to-severe plaque psoriasis
J INVEST DERMATOL. 2014; 134: S18-S18.-Annual Meeting of the Society-for-Investigative-Dermatology (SID); MAY 07-10, 2014; Albuquerque, NM. [Poster]
Web of Science

 

** Hochmeister, S; Birngruber, T; Adzemovic, MZ; Haindl, M; Fazekas, F; Ropele, S; Sinner, F Development of a cortical lesion in a new rat model of focal inflammatory demyelination in serial MRI
MULT SCLER J. 2014; 20: 237-237.-Joint ACTRIMS-ECTRIMS Meeting; SEP 10-13, 2014; Boston, MA. [Poster]
Web of Science

 

** Kolbinger, F; Bruin, G; Valentin, MA; Peters, TR; Khokhlovich, E; Jiang, X; Koroleva, I; Lee, D; SinneF, F; Pieber, T; Dragatin, C; Bodenlenz, M; Loesche, C Treatment with secukinumab rapidly leads to positive proteomic and transcriptional changes in psoriatic skin
EXP DERMATOL. 2014; 23: 11-11.-Inflammatory Skin Disease Summit - The Translational Revolution; NOV 19-21, 2014; Vienna, AUSTRIA. [Poster]
Web of Science

 

Kommentar

** Eisenberg, T; Schroeder, S; Büttner, S; Carmona-Gutierrez, D; Pendl, T; Andryushkova, A; Mariño, G; Pietrocola, F; Harger, A; Zimmermann, A; Magnes, C; Sinner, F; Sedej, S; Pieber, TR; Dengjel, J; Sigrist, S; Kroemer, G; Madeo, F A histone point mutation that switches on autophagy.
Autophagy. 2014; 10(6):1143-1145 Doi: 10.4161/auto.28767 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Ruckenstuhl, C; Netzberger, C; Entfellner, I; Carmona-Gutierrez, D; Kickenweiz, T; Stekovic, S; Gleixner, C; Schmid, C; Klug, L; Hajnal, I; Sorgo, AG; Eisenberg, T; Büttner, S; Marin O, G; Koziel, R; Magnes, C; Sinner, F; Pieber, TR; Jansen-Dürr, P; Fröhlich, KU; Kroemer, G; Madeo, F Autophagy extends lifespan via vacuolar acidification.
Microb Cell. 2014; 1(5): 160-162. Doi: 10.15698/mic2014.05.147 [OPEN ACCESS]
PubMed PUBMED Central FullText FullText_MUG

 

2013

Originalarbeit (Zeitschrift)

** Bauer, MA; Carmona-Gutiérrez, D; Ruckenstuhl, C; Reisenbichler, A; Megalou, EV; Eisenberg, T; Magnes, C; Jungwirth, H; Sinner, FM; Pieber, TR; Fröhlich, KU; Kroemer, G; Tavernarakis, N; Madeo, F Spermidine promotes mating and fertilization efficiency in model organisms.
Cell Cycle. 2013; 12(2):346-352 Doi: 10.4161/cc.23199 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Birngruber, T; Ghosh, A; Perez-Yarza, V; Kroath, T; Ratzer, M; Pieber, TR; Sinner, F Cerebral open flow microperfusion: a new in vivo technique for continuous measurement of substance transport across the intact blood-brain barrier.
Clin Exp Pharmacol Physiol. 2013; 40(12):864-871 Doi: 10.1111/1440-1681.12174
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** Bodenlenz, M; Aigner, B; Dragatin, C; Liebenberger, L; Zahiragic, S; Höfferer, C; Birngruber, T; Priedl, J; Feichtner, F; Schaupp, L; Korsatko, S; Ratzer, M; Magnes, C; Pieber, TR; Sinner, F Clinical applicability of dOFM devices for dermal sampling.
Skin Res Technol. 2013; 19(4):474-483 Doi: 10.1111/srt.12071
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** Bodenlenz, M; Dragatin, C; Hoefferer, C; Birngruber, T; Priedl, J; Feichtner, F; Schaller, R; Aigner, B; Korsatko, S; Pieber, TR; Sinner, F Certified dOFM sampling devices provide access to target tissue in pharmaceutical trials.
Biomed Tech (Berl). 2013; 58 Suppl 1(12): Doi: 10.1515/bmt-2013-4133
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** Coué, G; Freese, C; Unger, RE; Kirkpatrick, CJ; Pickl, KE; Sinner, FM; Engbersen, JF Design and physicochemical characterization of poly(amidoamine) nanoparticles and the toxicological evaluation in human endothelial cells: applications to peptide delivery to the brain.
J Biomater Sci Polym Ed. 2013; 24(8): 957-971. Doi: 10.1080/09205063.2012.727378
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** Gupta, VK; Scheunemann, L; Eisenberg, T; Mertel, S; Bhukel, A; Koemans, TS; Kramer, JM; Liu, KS; Schroeder, S; Stunnenberg, HG; Sinner, F; Magnes, C; Pieber, TR; Dipt, S; Fiala, A; Schenck, A; Schwaerzel, M; Madeo, F; Sigrist, SJ Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner.
Nat Neurosci. 2013; 16(10):1453-1460 Doi: 10.1038/nn.3512 [OPEN ACCESS]
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** Hajnsek, M; Harrich, D; Schiffer, D; Guebitz, G; Sinner, F Sensor for early detection of wound infection.
Biomed Tech (Berl). 2013; 58 Suppl 1(12): Doi: 10.1515/bmt-2013-4147
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** Hajnsek, M; Nacht, B; Sax, S; List, E; Klimant, I; Sinner, F Single-port glucose monitoring with simultaneous insulin infusion.
Biomed Tech (Berl). 2013; 58 Suppl 1(12): Doi: 10.1515/bmt-2013-4144
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** Mader, JK; Birngruber, T; Korsatko, S; Deller, S; Köhler, G; Boysen, S; Augustin, T; Mautner, SI; Sinner, F; Pieber, TR; AP@home Consortium Enhanced absorption of insulin aspart as the result of a dispersed injection strategy tested in a randomized trial in type 1 diabetic patients.
Diabetes Care. 2013; 36(4):780-785 Doi: 10.2337/dc12-1319 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Painsipp, E; Köfer, MJ; Farzi, A; Dischinger, US; Sinner, F; Herzog, H; Holzer, P Neuropeptide Y and peptide YY protect from weight loss caused by Bacille Calmette-Guérin in mice.
Br J Pharmacol. 2013; 170(5):1014-1026 Doi: 10.1111/bph.12354 [OPEN ACCESS]
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** Rumpler, M; Suppan, M; Hajnsek, M; Satzinger, V; Köstler, S; Sinner, F Design and evaluation of a microfluidic-based whole blood pre-treatment module to detect folic acid.
Biomed Tech (Berl). 2013; 58 Suppl 1(12): Doi: 10.1515/bmt-2013-4137
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** Schwingenschuh, S; Hajnsek, M; Scharfetter, H; Martinsen, OG; Tiffner, K; Dragatin, C; Raml, R; Mautner, A; Bodenlenz, M; Sinner, F Skin impedance measurements support ex-vivo penetration studies for topical applied drugs.
Biomed Tech (Berl). 2013; 58 Suppl 1(12): Doi: 10.1515/bmt-2013-4420 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Bruin, G; Dragatin, C; Aigner, B; Polus, F; Calonder, C; Froeliger, C; Tiffner, K; Bodenlenz, M; Mader, J; Korsatko, S; Ratzer, M; Pieber, TR; Loesche, C; Sinner, F; Absolute levels of the novel anti-IL-17A antibody, secukinumab, in skin can be quantified by dermal open flow microperfusion (dOFM).
J INVEST DERMATOL. 2013; 133: S52-S52.-International Investigative Dermatology Meeting; MAY 08-11, 2013; Edinburgh, SCOTLAND. [Poster]
Web of Science

 

** Hochmeister, S; Birngruber, T; Zeitelhofer-Adzemovic, M; Haindl, M; Sinner, F A new model of focal inflammatory demyelination in the neocortex of the rat
MULT SCLER J. 2013; 19(11): 137-138. [Poster]
Web of Science

 

** Hofferer, C; Pieber, TR; Tutkur, D; Mautner, SI; Damgaard, J; Naver, H; Jeppesen, CB; Nishimura, E; Brand, CL; Fledelius, C; Sinner, F Adipose tissue levels of human insulin and insulin detemir measured with open flow microperfusion (OFM) during constant intravenous infusion
DIABETOLOGIA. . 2013; 56: S416-S416.-49th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD); SEP 23-27, 2013; Barcelona, SPAIN. [Poster]
Web of Science

 

Originalarbeit (Konferenzband)

** Hajnsek, M; Harrich, D; Schiffer, D; Guebitz, G; Sinner, F Sensor for early detection of wound infection
BIOMED ENG-BIOMED TE. 2013; 58: Doi: 10.1515/bmt-2013-4147
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** Hajnsek, M; Nacht, B; Sax, S; List, E; Klimant, I; Sinner, F Single-port glucose monitoring with simultaneous insulin infusion
BIOMED ENG-BIOMED TE. 2013; 58: Doi: 10.1515/bmt-2013-4144
Web of Science FullText FullText_MUG

 

** Rumpler, M; Suppan, M; Hajnsek, M; Satzinger, V; Kostler, S; Sinner, F Design and evaluation of a microfluidic-based whole blood pre-treatment module to detect folic acid
BIOMED ENG-BIOMED TE. 2013; 58: Doi: 10.1515/bmt-2013-4137
Web of Science FullText FullText_MUG

 

** Schwingenschuh, S; Hajnsek, M; Scharfetter, H; Martinsen, OG; Tiffner, K; Dragatin, C; Raml, R; Mautner, A; Bodenlenz, M; Sinner, F Skin impedance measurements support ex-vivo penetration studies for topical applied drugs
BIOMED ENG-BIOMED TE. 2013; 58: Doi: 10.1515/bmt-2013-4420
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2012

Originalarbeit (Zeitschrift)

** Bodenlenz, M; Höfferer, C; Magnes, C; Schaller-Ammann, R; Schaupp, L; Feichtner, F; Ratzer, M; Pickl, K; Sinner, F; Wutte, A; Korsatko, S; Köhler, G; Legat, FJ; Benfeldt, EM; Wright, AM; Neddermann, D; Jung, T; Pieber, TR Dermal PK/PD of a lipophilic topical drug in psoriatic patients by continuous intradermal membrane-free sampling.
Eur J Pharm Biopharm. 2012; 81(3):635-641 Doi: 10.1016/j.ejpb.2012.04.009
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** Gatschelhofer, C; Prasch, A; Buchmeiser, MR; Zimmer, A; Wernig, K; Griesbacher, M; Pieber, TR; Sinner, FM Monolithic precolumns as efficient tools for guiding the design of nanoparticulate drug-delivery formulations.
Anal Chem. 2012; 84(17):7415-7421 Doi: 10.1021/ac3012208
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** Holmgaard, R; Benfeldt, E; Nielsen, JB; Gatschelhofer, C; Sorensen, JA; Höfferer, C; Bodenlenz, M; Pieber, TR; Sinner, F Comparison of open-flow microperfusion and microdialysis methodologies when sampling topically applied fentanyl and benzoic acid in human dermis ex vivo.
Pharm Res. 2012; 29(7):1808-1820 Doi: 10.1007/s11095-012-0705-9
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** Moustafa, T; Fickert, P; Magnes, C; Guelly, C; Thueringer, A; Frank, S; Kratky, D; Sattler, W; Reicher, H; Sinner, F; Gumhold, J; Silbert, D; Fauler, G; Höfler, G; Lass, A; Zechner, R; Trauner, M Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Gastroenterology. 2012; 142(1):140-151 Doi: 10.1053/j.gastro.2011.09.051
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** Paar, M; Jüngst, C; Steiner, NA; Magnes, C; Sinner, F; Kolb, D; Lass, A; Zimmermann, R; Zumbusch, A; Kohlwein, SD; Wolinski, H Remodeling of lipid droplets during lipolysis and growth in adipocytes.
J Biol Chem. 2012; 287(14):11164-11173 Doi: 10.1074/jbc.M111.316794 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Abstract (Zeitschrift)

** Aigner, BA; Bodenlenz, M; Hofferer, C; Priedl, J; Dragatin, C; Kiefer, B; Korsatko, S; Liebenberger, L; Zahiragic, S; Raml, R; Magnes, C; Becker, JC; Pieber, TR; Sinner, F Dermal open-flow microperfusion as a novel technique for in vivo measurement of dermal interstitium
EXP DERMATOL. 2012; 21(3):e13-e13.-39th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF); MAR 01-03, 2012; Marburg, GERMANY. [Poster]
Web of Science

 

2011

Originalarbeit (Zeitschrift)

** Ardjomand-Woelkart, K; Kollroser, M; Magnes, C; Sinner, F; Frye, RF; Derendorf, H; Bauer, R; Butterweck, V Absolute/relative bioavailability and metabolism of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides (tetraenes) after intravenous and oral single doses to rats.
Planta Med. 2011; 77(16):1794-1799 Doi: 10.1055/s-0030-1271120
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** Carmona-Gutiérrez, D; Bauer, MA; Ring, J; Knauer, H; Eisenberg, T; Büttner, S; Ruckenstuhl, C; Reisenbichler, A; Magnes, C; Rechberger, GN; Birner-Gruenberger, R; Jungwirth, H; Fröhlich, KU; Sinner, F; Kroemer, G; Madeo, F The propeptide of yeast cathepsin D inhibits programmed necrosis.
Cell Death Dis. 2011; 2(16):e161-e161 Doi: 10.1038/cddis.2011.43 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Millotti, G; Perera, G; Vigl, C; Pickl, K; Sinner, FM; Bernkop-Schnürch, A The use of chitosan-6-mercaptonicotinic acid nanoparticles for oral peptide drug delivery.
Drug Deliv. 2011; 18(3): 190-197. Doi: 10.3109/10717544.2010.522611
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** Painsipp, E; Köfer, MJ; Sinner, F; Holzer, P Prolonged depression-like behavior caused by immune challenge: influence of mouse strain and social environment.
PLoS One. 2011; 6(6):e20719-e20719 Doi: 10.1371/journal.pone.0020719 [OPEN ACCESS]
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** Pickl, KE; Adamek, V; Gorges, R; Sinner, FM Headspace-SPME-GC/MS as a simple cleanup tool for sensitive 2,6-diisopropylphenol analysis from lipid emulsions and adaptable to other matrices.
J Pharm Biomed Anal. 2011; 55(5): 1231-1236. Doi: 10.1016/j.jpba.2011.03.019
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Abstract (Zeitschrift)

** Bodenlenz, M; Hoefferer, C; Priedl, J; Dragatin, C; Korsatko, S; Liebenberger, L; Zahiragic, S; Raml, R; Magnes, C; Pieber, T; Sinner, F A novel certified dermal sampling system for efficient clinical research
J INVEST DERMATOL. 2011; 131: S44-S44. [Poster]
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2010

Originalarbeit (Zeitschrift)

** Chandak, PG; Radovic, B; Aflaki, E; Kolb, D; Buchebner, M; Fröhlich, E; Magnes, C; Sinner, F; Haemmerle, G; Zechner, R; Tabas, I; Levak-Frank, S; Kratky, D Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase.
J Biol Chem. 2010; 285(26):20192-20201 Doi: 10.1074/jbc.M110.107854 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Moustafa, T; Fickert, P; Magnes, C; Frank, S; Kratky, D; Sinner, F; Gumhold, J; Silbert, D; Halsegger, S; Trauner M METABOLIC REPROGRAMMING OF LIPID METABOLISM BY THE SIDE-CHAIN MODIFIED BILE ACID, 24-NORURSODEOXYCHOLIC ACID, RESTORES INFLAMMATION-DRIVEN LIVER INJURY AND ABERRANT PROLIFERATION IN ABCB4-/- MICE
J HEPATOL. 2010; 52: S20-S21.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)60049-9 [Oral Communication]
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2009

Originalarbeit (Zeitschrift)

** Eisenberg, T; Knauer, H; Schauer, A; Büttner, S; Ruckenstuhl, C; Carmona-Gutierrez, D; Ring, J; Schroeder, S; Magnes, C; Antonacci, L; Fussi, H; Deszcz, L; Hartl, R; Schraml, E; Criollo, A; Megalou, E; Weiskopf, D; Laun, P; Heeren, G; Breitenbach, M; Grubeck-Loebenstein, B; Herker, E; Fahrenkrog, B; Fröhlich, KU; Sinner, F; Tavernarakis, N; Minois, N; Kroemer, G; Madeo, F Induction of autophagy by spermidine promotes longevity.
Nat Cell Biol. 2009; 11(11):1305-1314 Doi: 10.1038/ncb1975 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Magnes, C; Suppan, M; Pieber, TR; Sinner, FM Acyl CoA-profiling in biological tissues using online SPE-LC-FTMS (Orbitrap)
DIABETOLOGIA. 2009; 52: 707--45th EASD Annual Meeting of the European Association for the Study of Diabetes; SEP 30 - OCT 2, 2009; Vienna, Austria. [Poster]
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** Pickl, KE; Magnes, C; Pieber, TR; Sinner, FM A new strategy for the sensitive and simultaneous analysis of human insulin and insulin analogues using LC/MS2 in combination with a tailored sample clean-up procedure
DIABETOLOGIA. 2009; 52: 1027--45th EASD Annual Meeting of the European Association for the Study of Diabetes; SEP 30 - OCT 2, 2009; Vienna, Austria. [Poster]
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Originalarbeit (Konferenzband)

** Gatschelhofer, C; Mautner, A; Reiter, F; Pieber, TR; Buchmeiser, MR; Sinner, FM Ring-opening metathesis polymerization for the preparation of norbornene-based weak cation-exchange monolithic capillary columns
J CHROMATOGR A. 2009; 1216(13): 2651-2657. Doi: 10.1016/j.chroma.2008.11.006
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2008

Originalarbeit (Zeitschrift)

** Horvath, K; Bock, G; Regittnig, W; Bodenlenz, M; Wutte, A; Plank, J; Magnes, C; Sinner, F; Fürst-Recktenwald, S; Theobald, K; Pieber, TR Insulin glulisine, insulin lispro and regular human insulin show comparable end-organ metabolic effects: an exploratory study.
Diabetes Obes Metab. 2008; 10(6):484-491 Doi: 10.1111/j.1463-1326.2007.00734.x
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** Magnes, C; Suppan, M; Pieber, TR; Moustafa, T; Trauner, M; Haemmerle, G; Sinner, FM Validated comprehensive analytical method for quantification of coenzyme A activated compounds in biological tissues by online solid-phase extraction LC/MS/MS.
Anal Chem. 2008; 80(15):5736-5742 Doi: 10.1021/ac800031u
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** Sinner, FM; Gatschelhofer, C; Mautner, A; Magnes, C; Buchmeiser, MR; Pieber, TR Ring-opening metathesis polymerization-derived monolithic capillary columns for high-performance liquid chromatography. Downscaling and application in medical research.
J Chromatogr A. 2008; 1191(1-2):274-281 Doi: 10.1016/j.chroma.2008.01.005
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2007

Originalarbeit (Zeitschrift)

** Pickl, KE; Magnes, C; Bodenlenz, M; Pieber, TR; Sinner, FM Rapid online-SPE-MS/MS method for ketoprofen determination in dermal interstitial fluid samples from rats obtained by microdialysis or open-flow microperfusion.
J Chromatogr B Analyt Technol Biomed Life Sci. 2007; 850(1-2):432-439 Doi: 10.1016/j.jchromb.2006.12.026
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** Sedláková, P; Miksik, I; Gatschelhofer, C; Sinner, FM; Buchmeiser, MR Voltage-assisted capillary LC of peptides using monolithic capillary columns prepared by ring-opening metathesis polymerization.
Electrophoresis. 2007; 28(13): 2219-2222. Doi: 10.1002/elps.200700125
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** Wutte, A; Plank, J; Bodenlenz, M; Magnes, C; Regittnig, W; Sinner, F; Ronn, B; Zdravkovic, M; Pieber, TR Proportional dose-response relationship and lower within-patient variability of insulin deternir and NPH insulin in subjects with type 1 diabetes mellitus
EXP CLIN ENDOCRINOL DIABETES. 2007; 115(7): 461-467. Doi: 10.1055/s-2007-976512
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2006

Originalarbeit (Zeitschrift)

** Gatschelhofer, C; Schmid, MG; Schreiner, K; Pieber, TR; Sinner, FM; Gübitz, G Enantioseparation of glycyl-dipeptides by CEC using particle-loaded monoliths prepared by ring-opening metathesis polymerization (ROMP).
J Biochem Biophys Methods. 2006; 69(1-2):67-77 Doi: 10.1016/j.jbbm.2006.01.010
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** Schlemmer, B; Gatschelhofer, C; Pieber, TR; Sinner, FM; Buchmeiser, MR Poly(cyclooctene)-based monolithic columns for capillary high performance liquid chromatography prepared via ring-opening metathesis polymerization.
J Chromatogr A. 2006; 1132(1-2):124-131 Doi: 10.1016/j.chroma.2006.07.058
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2005

Originalarbeit (Zeitschrift)

** Bodenlenz, M; Schaupp, LA; Druml, T; Sommer, R; Wutte, A; Schaller, HC; Sinner, F; Wach, P; Pieber, TR Measurement of interstitial insulin in human adipose and muscle tissue under moderate hyperinsulinemia by means of direct interstitial access.
Am J Physiol Endocrinol Metab. 2005; 289(2):E296-E300 Doi: 10.1152/ajpendo.00431.2004 [OPEN ACCESS]
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** Gatschelhofer, C; Magnes, C; Pieber, TR; Buchmeiser, MR; Sinner, FM Evaluation of ring-opening metathesis polymerization (ROMP)-derived monolithic capillary high performance liquid chromatography columns
J CHROMATOGR A. 2005; 1090: 81-89. Doi: 10.1016/j.chroma.2005.06.098
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** Gatschelhofer, C; Magnes, C; Pieber, TR; Buchmeiser, MR; Sinner, FM Evaluation of ring-opening metathesis polymerization (ROMP)-derived monolithic capillary high performance liquid chromatography columns.
J Chromatogr A. 2005; 1090(1-2): 81-89. Doi: 10.1016/j.chroma.2005.06.098
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** Magnes, C; Sinner, FM; Regittnig, W; Pieber, TR LC/MS/MS method for quantitative determination of long-chain fatty acyl-CoAs.
Anal Chem. 2005; 77(9):2889-2894 Doi: 10.1021/ac048314i
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** Plank, J; Bodenlenz, M; Sinner, F; Magnes, C; Görzer, E; Regittnig, W; Endahl, LA; Draeger, E; Zdravkovic, M; Pieber, TR A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of the long-acting insulin analog detemir.
Diabetes Care. 2005; 28(5):1107-1112 Doi: 10.2337/diacare.28.5.1107 [OPEN ACCESS]
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2003

Abstract (Zeitschrift)

** Bodenlenz, M; Sommer, R; Wutte, A; Druml, T; Sinner, F; Plank, J; Schaller, HC; Schaupp, L; Wach, P; Pieber, TR Quantification of the human insulin concentration in adipose and muscle tissue of healthy subjects by means of the No-Net-Flux calibration technique and Open-Flow Microperfusion
DIABETOLOGIA 2003 46: 585-585.
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2001

Originalarbeit (Zeitschrift)

** Eder, K; Sinner, F; Mupa, M; Huber, CG; Buchmeiser, MR Evaluation of norbornene- beta-cyclodextrin-based monomers and oligomers as chiral selectors by means of nonaqueous capillary electrophoresis.
Electrophoresis. 2001; 22(1):109-116 Doi: 10.1002/1522-2683(200101)22:1<109::AID-ELPS109>3.0.CO;2-P
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** Mayr, B; Sinner, F; Buchmeiser, MR Chiral beta-cyclodextrin-based polymer supports prepared via ring-opening metathesis graft-polymerization.
J Chromatogr A. 2001; 907(1-2):47-56 Doi: 10.1016/s0021-9673(00)01008-6
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2000

Originalarbeit (Zeitschrift)

** Sinner, FM; Buchmeiser, MR Ring-Opening Metathesis Polymerization: Access to a New Class of Functionalized, Monolithic Stationary Phases for Liquid Chromatography.
Angew Chem Int Ed Engl. 2000; 39(8):1433-1436 Doi: 10.1002/(sici)1521-3773(20000417)39:8<1433::aid-anie1433>3.0.co;2-b
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