Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
El-Heliebi Amin |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2025
Originalarbeit (Zeitschrift)
** Berghoff, AS; Mair, MJ; Spiró, Z; Abdel, Malak, C; El-Heliebi, A; Eckert, F; Furtner, J; König, F; Leibetseder, A; Nowosielski, M; Oberndorfer, S; Prietl, B; Pichler, J; Pieber, TR; Spiegl-Kreinecker, S; Urbanic, Purkart, T; Wöhrer, A; Widhalm, G; Preusser, M, , ATTRACT, study, group,
Personalized targeted glioblastoma therapies by ex vivo drug screening: Study protocol of the Advanced brain Tumor TheRApy Clinical Trial (ATTRACT).
Neurooncol Adv. 2025; 7(1):vdaf056
Doi: 10.1093/noajnl/vdaf056
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** Joch, S; Smolle, MA; Kashofer, K; Thüringer, A; Szkandera, J; Benesch, M; El-Heliebi, A; Liegl-Atzwanger, B; Leithner, A; Seidel, MG
New Insights from Long-Term Clinical Use of Circulating Tumor DNA-Based Minimal Residual Disease Monitoring in Translocation-Associated Sarcomas.
Oncol Res Treat. 2025; 48(4):186-196
Doi: 10.1159/000543223
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** Lyssy, F; Forstner, D; Guettler, J; Kupper, N; Ujčič, K; Neuper, L; Daxboeck, C; El-Heliebi, A; Kummer, D; Krappinger, JC; Vejzovic, D; Rinner, B; Cvirn, G; Wernitznig, S; Moser, G; Valdes, DS; Herse, F; Höbler, AL; Pollheimer, J; James, JL; Feichtinger, J; Gauster, M
Maternal platelet-derived factors induce trophoblastic LAIR2 expression to promote trophoblast invasion and inhibit platelet activation at the fetal-maternal interface.
J Thromb Haemost. 2025; 23(6):2010-2024
Doi: 10.1016/j.jtha.2025.03.020
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** Nonn, O; Debnath, O; Valdes, DS; Sallinger, K; Secener, AK; Fischer, C; Tiesmeyer, S; Nimo, J; Kuenzer, T; Ulrich, J; Maxian, T; Knöfler, M; Karau, P; Bartolomaeus, H; Kroneis, T; Frolova, A; Neuper, L; Haase, N; Malt, A; Müller-Bötticher, N; Kräker, K; Kedziora, S; Forstner, D; Eils, R; Schmidt-Ullrich, R; Haider, S; Verlohren, S; Stern, C; Sugulle, M; Jones, S; Thilaganathan, B; Kaitu'u-Lino, TJ; Tong, S; Huppertz, B; El-Heliebi, A; Staff, AC; Coscia, F; Müller, DN; Dechend, R; Gauster, M; Ishaque, N; Herse, F
Senescent Syncytiotrophoblast Secretion During Early Onset Preeclampsia.
Hypertension. 2025; 82(5):787-799
Doi: 10.1161/HYPERTENSIONAHA.124.23362
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Abstract (Zeitschrift)
** Slaats, E; Sallinger, K; Bonstingl, L; Schuch, K; Schönberger, JM; Bramreiter, BL; Gruber, MC; Anholds, JDH; Drabbles, JJM; El-Heliebi, A; Eikmans, M; Kroneis, T
Image-based SNP detection for the identification of microchimeric cells within a tissue
J REPROD IMMUNOL. 2025; 167: 15-15.-European Society for Reproductive Immunology; OCT 9-11, 2024; Leiden, THE NETHERLANDS.
Doi: 10.1016/j.jri.2024.104368
[Poster]
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2024
Originalarbeit (Zeitschrift)
** Bonstingl, L; Skofler, C; Ulz, C; Zinnegger, M; Sallinger, K; Schönberger, J; Schuch, K; Pankratz, K; Borrás-Cherrier, A; Somodi, V; Abuja, PM; Oberauner-Wappis, L; Moser, T; Heitzer, E; Bauernhofer, T; Kroneis, T; El-Heliebi, A
Clinical Application of ISO and CEN/TS Standards for Liquid Biopsies-Information Everybody Wants but Nobody Wants to Pay For.
Clin Chem. 2024; 70(9): 1140-1150.
Doi: 10.1093/clinchem/hvae079
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** Bonstingl, L; Zinnegger, M; Sallinger, K; Pankratz, K; Müller, CT; Pritz, E; Odar, C; Skofler, C; Ulz, C; Oberauner-Wappis, L; Borrás-Cherrier, A; Somođi, V; Heitzer, E; Kroneis, T; Bauernhofer, T; El-Heliebi, A
Advanced single-cell and spatial analysis with high-multiplex characterization of circulating tumor cells and tumor tissue in prostate cancer: Unveiling resistance mechanisms with the CoDuCo in situ assay.
Biomark Res. 2024; 12(1): 140
Doi: 10.1186/s40364-024-00680-z
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** Glader, C; Jeitler, R; Stanzer, S; Harbusch, N; Prietl, B; El-Heliebi, A; Selmani, A; Fröhlich, E; Mussbacher, M; Roblegg, E
Investigation of nanostructured lipid carriers for fast intracellular localization screening using the Echo liquid handler.
Int J Pharm. 2024; 665:124698
Doi: 10.1016/j.ijpharm.2024.124698
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** Lyssy, F; Forstner, D; Brugger, BA; Ujčič, K; Guettler, J; Kupper, N; Wernitznig, S; Daxboeck, C; Neuper, L; El-Heliebi, A; Kloimboeck, T; Kargl, J; Huppertz, B; Ghaffari-Tabrizi-Wizsy, N; Gauster, M
The chicken chorioallantoic membrane assay revisited - A face-lifted approach for new perspectives in placenta research.
Placenta. 2024;
Doi: 10.1016/j.placenta.2024.04.013
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** Stitz, R; Stoiber, F; Silye, R; Vlachos, G; Andaloro, S; Rebhan, E; Dunzinger, M; Pühringer, F; Gallo, C; El-Heliebi, A; Heitzer, E; Hauser-Kronberger, C
Clinical Implementation of a Noninvasive, Multi-Analyte Droplet Digital PCR Test to Screen for Androgen Receptor Alterations.
J Mol Diagn. 2024; 26(6):467-478
Doi: 10.1016/j.jmoldx.2024.02.009
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** Welsch, E; Bonstingl, L; Holzer, B; Schuster, E; Weiß, E; Zaharie, AT; Krainer, M; Fischer, MB; El-Heliebi, A; Zeillinger, R; Obermayr, E
Multi-marker analysis of circulating tumor cells in localized intermediate/high-risk and metastatic prostate cancer.
Clin Exp Metastasis. 2024; 41(6):937-945
Doi: 10.1007/s10585-024-10313-2
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Korrektur
** Bonstingl, L; Zinnegger, M; Sallinger, K; Pankratz, K; Müller, CT; Pritz, E; Odar, C; Skofler, C; Ulz, C; Oberauner-Wappis, L; Borrás-Cherrier, A; Somođi, V; Heitzer, E; Kroneis, T; Bauernhofer, T; El-Heliebi, A
Correction: Advanced single-cell and spatial analysis with high-multiplex characterization of circulating tumor cells and tumor tissue in prostate cancer: unveiling resistance mechanisms with the CoDuCo in situ assay.
Biomark Res. 2024; 12(1): 150
Doi: 10.1186/s40364-024-00698-3
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Abstract (Zeitschrift)
** Lyssy, F; Forstner, D; Guettler, J; Kupper, N; Ujcic, K; Wernitznig, S; Neuper, L; Daxboeck, C; El-Heliebi, A; Krappinger, J; Feichtinger, J; Cvirn, G; Hoebler, AL; Pollheimer, J; James, J; Gauster, M
PLATELET-DERIVED FACTORS MODIFY GENE EXPRESSION PROFILE OF HUMAN TROPHOBLASTS
PLACENTA. 2024; 154: E43-E43.-Annual Conference of the International-Federation-of-Placenta-Associations (IFPA); SEP 2-6, 2024; Montreal, CANADA.
[Poster]
Web of Science
** Sallinger, K; Gruber, M; Müller, C; Bonstingl, L; Pritz, E; Pankratz, K; Gerger, A; Smolle, MA; Aigelsreiter, A; Surova, O; Svedlund, J; Nilsson, M; Kroneis, T; El-Heliebi, A
Imaging-based spatial transcriptomics technology identifies predictive biomarkers for relapse in colon cancer stage II.
MOL BIOL CELL. 2024; 35(1): 618-618.
Web of Science
** Stanzer, S; Bandres-Meriz, J; Harbusch, N; Franz, J; Mahdy-Ali, K; Monedeiro, FDS; Magnes, C; Zügner, E; Pieber, T; El-Heliebi, A; Urbanic, T; Woehrer, A; Prietl, B
Linking cellular drug responses to corresponding metabolomic tissue signatures in gliomas
ANN ONCOL. 2024; 35: S424-S424.
Doi: 10.1016/j.annonc.2024.08.561
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** Stanzer, S; Bandres-Meriz, J; Harbusch, N; Franz, J; Mahdy-Ali, K; Monedeiro, FFDS; Magnes, C; Zügner, E; Pieber, T; El-Heliebi, A; Purkart, TU; Wöhrer, A; Prietl, B
ASSOCIATION OF CELLULAR DRUG RESPONSES AND METABOLIC PROFILES IN ADULT TYPE DIFFUSE GLIOMAS
NEURO-ONCOLOGY. 2024; 26: -29th SNO Annual Meeting; NOV 21-24, 2024; Houston, USA.
Doi: 10.1093/neuonc/noae144.321
[Poster]
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Pre-print
** Benezeder, T; Bordag, N; Woltsche, J; Teufelberger, A; Perchthaler, I; Weger, W; Salmhofer, W; Gruber-Wackernagel, A; Painsi, C; Zhan, Q; El-Heliebi, A; Babina, M; Clark, R; Wolf, P
Mast cells express IL17A, IL17F and RORC, are activated and persist with IL-17 production in resolved skin of patients with chronic plaque-type psoriasis.
Res Sq. 2024;
Doi: 10.21203/rs.3.rs-3958361/v1
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2023
Originalarbeit (Zeitschrift)
** Brugger, BA; Neuper, L; Guettler, J; Forstner, D; Wernitznig, S; Kummer, D; Lyssy, F; Feichtinger, J; Krappinger, J; El-Heliebi, A; Bonstingl, L; Moser, G; Rodriguez-Blanco, G; Bachkönig, OA; Gottschalk, B; Gruber, M; Nonn, O; Herse, F; Verlohren, S; Frank, HG; Barapatre, N; Kampfer, C; Fluhr, H; Desoye, G; Gauster, M
Fluid shear stress induces a shift from glycolytic to amino acid pathway in human trophoblasts.
Cell Biosci. 2023; 13(1): 163
Doi: 10.1186/s13578-023-01114-3
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** Kendzia, S; Franke, S; Kröhler, T; Golob-Schwarzl, N; Schweiger, C; Toeglhofer, AM; Skofler, C; Uranitsch, S; El-Heliebi, A; Fuchs, J; Punschart, A; Stiegler, P; Keil, M; Hoffmann, J; Henderson, D; Lehrach, H; Yaspo, ML; Reinhard, C; Schäfer, R; Keilholz, U; Regenbrecht, C; Schicho, R; Fickert, P; Lax, SF; Erdmann, F; Schulz, MH; Kiemer, AK; Haybaeck, J; Kessler, SM
A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer.
Mol Cancer. 2023; 22(1):89
Doi: 10.1186/s12943-023-01787-x
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** Nonn, O; Bonstingl, L; Sallinger, K; Neuper, L; Fuchs, J; Gauster, M; Huppertz, B; Brislinger, D; El-Heliebi, A; Fluhr, H; Kampelmühler, E; Klaritsch, P
Maternal COVID-19 causing intrauterine foetal demise with microthrombotic placental insufficiency: a case report.
BMC Pregnancy Childbirth. 2023; 23(1): 653
Doi: 10.1186/s12884-023-05942-6
(- Case Report)
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** Sallinger, K; Gruber, M; Müller, CT; Bonstingl, L; Pritz, E; Pankratz, K; Gerger, A; Smolle, MA; Aigelsreiter, A; Surova, O; Svedlund, J; Nilsson, M; Kroneis, T; El-Heliebi, A
Spatial tumour gene signature discriminates neoplastic from non-neoplastic compartments in colon cancer: unravelling predictive biomarkers for relapse.
J Transl Med. 2023; 21(1): 528
Doi: 10.1186/s12967-023-04384-0
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Korrektur
** Golob-Schwarzl, N; Schweiger, C; Koller, C; Krassnig, S; Gogg-Kamerer, M; Gantenbein, N; Toeglhofer, AM; Wodlej, C; Bergler, H; Pertschy, B; Uranitsch, S; Holter, M; El-Heliebi, A; Fuchs, J; Punschart, A; Stiegler, P; Keil, M; Hoffmann, J; Henderson, D; Lehrach, H; Reinhard, C; Regenbrecht, C; Schicho, R; Fickert, P; Lax, S; Haybaeck, J
Correction: Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.
Oncotarget. 2023; 14: 83-84.
Doi: 10.18632/oncotarget.28115
[OPEN ACCESS]
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Abstract (Zeitschrift)
** Benezeder, T; Woltsche, J; Bordag, N; Teufelberger, A; Perchthaler, I; Weger, W; Gruber-Wackernagl, A; Salmhofer, W; Painsi, C; Pankratz, K; El-Heliebi, A; Babina, M; Clark, R; Wolf, P
Mast cells as potential drivers of inflammation in psoriasis
J INVEST DERMATOL. 2023; 143(11):S342-S342.-5th Inflammatory Skin Disease Summit (ISDS); NOV 15-18, 2023; Vienna, AUSTRIA.
[Poster]
Web of Science
** Sparovec, TG; Mihalic, ZN; Schoell, W; Tomasch, G; El-Heliebi, A; Kroneis, T; Marteau, V; Trajanoski, Z; Jones, HN; Kargl, J; Gold, D
Characterization of the Placental Bed Microenvironment in Placenta Accreta Spectrum Disorders
REPROD SCI. 2023; 30: 103A-103A.-70th Annual Meeting of the Society for Reproductive Investigation (SRI); MAR 21-25, 2023; Brisbane, AUSTRALIA.
[Oral Communication]
Web of Science
2022
Originalarbeit (Zeitschrift)
** Seidel, MG; Kashofer, K; Moser, T; Thueringer, A; Liegl-Atzwanger, B; Leithner, A; Szkandera, J; Benesch, M; El-Heliebi, A; Heitzer, E
Clinical implementation of plasma cell-free circulating tumor DNA quantification by digital droplet PCR for the monitoring of Ewing sarcoma in children and adolescents.
Front Pediatr. 2022; 10: 926405
Doi: 10.3389/fped.2022.926405
[OPEN ACCESS]
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Abstract (Zeitschrift)
** El-Heliebi, A; Prietl, B; Mahdy-Ali, K; Purkart, TU; Gerlitz, L; Skofler, C; Stanzer, S; Franz, J; Harbusch, N; Madl, T; Widhalm, G; Rossler, K; Tomberger, M; Mattersdorfer, K; Kroneis, T; Oberhuber, M; Pieber, TR
Next generation drug screening platform: generation of patient-derived cells for ex vivo drug response studies of gliomas
NEURO-ONCOLOGY. 2022; 24: -Brain Tumor Meeting 2022; May 19-20, 2022; Berlin, GERMANY.
Doi: 10.1093/neuonc/noac174.180
[Poster]
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** El-Heliebi, A; Urbanic-Purkart, T; Mahdy-Ali, K; Skofler, C; Gerlitz, L; Stanzer, S; Franz, J; Harbusch, N; Madl, T; Widhalm, G; Rossler, K; Tomberger, M; Mattersdorfer, K; Kroneis, T; Oberhuber, M; Pieber, T; Prietl, B
PATIENT-DERIVED CELLS FOR EX VIVO DRUG SCREENING STUDIES OF GLIOMAS
NEURO-ONCOLOGY. 2022; 24: 209-209.-27th Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology (SNO); NOV 16-20, 2022; Tampa, FL.
[Poster]
Web of Science
2021
Originalarbeit (Zeitschrift)
** Nonn, O; Fischer, C; Geisberger, S; El-Heliebi, A; Kroneis, T; Forstner, D; Desoye, G; Staff, AC; Sugulle, M; Dechend, R; Pecks, U; Kollmann, M; Stern, C; Cartwright, JE; Whitley, GS; Thilaganathan, B; Wadsack, C; Huppertz, B; Herse, F; Gauster, M
Maternal Angiotensin Increases Placental Leptin in Early Gestation via an Alternative Renin-Angiotensin System Pathway: Suggesting a Link to Preeclampsia.
Hypertension. 2021; 77(5):1723-1736
Doi: 10.1161/HYPERTENSIONAHA.120.16425
[OPEN ACCESS]
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** Smolle, MA; Herbsthofer, L; Goda, M; Granegger, B; Brcic, I; Bergovec, M; Scheipl, S; Prietl, B; El-Heliebi, A; Pichler, M; Gerger, A; Posch, F; Tomberger, M; López-García, P; Feichtinger, J; Baumgartner, C; Leithner, A; Liegl-Atzwanger, B; Szkandera, J
Influence of tumor-infiltrating immune cells on local control rate, distant metastasis, and survival in patients with soft tissue sarcoma.
Oncoimmunology. 2021; 10(1):1896658
Doi: 10.1080/2162402X.2021.1896658
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** Smolle, MA; Herbsthofer, L; Granegger, B; Goda, M; Brcic, I; Bergovec, M; Scheipl, S; Prietl, B; Pichler, M; Gerger, A; Rossmann, C; Riedl, J; Tomberger, M; López-García, P; El-Heliebi, A; Leithner, A; Liegl-Atzwanger, B; Szkandera, J
T-regulatory cells predict clinical outcome in soft tissue sarcoma patients: a clinico-pathological study.
Br J Cancer. 2021; 125(5):717-724
Doi: 10.1038/s41416-021-01456-0
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Übersichtsarbeit
** Krappinger, JC; Bonstingl, L; Pansy, K; Sallinger, K; Wreglesworth, NI; Grinninger, L; Deutsch, A; El-Heliebi, A; Kroneis, T; Mcfarlane, RJ; Sensen, CW; Feichtinger, J
Non-coding Natural Antisense Transcripts: Analysis and Application.
J Biotechnol. 2021; 340:75-101
Doi: 10.1016/j.jbiotec.2021.08.005
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Abstract (Zeitschrift)
** Nonn, O; Debnath, O; Valdes, DS; Fischer, C; Secener, K; Tiesmeyer, S; Ishaque, N; Sallinger, K; El-Heliebi, A; Staff, A; Dominik, NM; Dechend, R; Gauster, M; Herse, F
Unravelling Cell-specific Interactions At The Preeclamptic Maternal-foetal Interface From Early To Late Pregnancy
HYPERTENSION. 2021; 78:
Doi: 10.1161/hyp.78.suppl_1.27
[Onlinepräsentation]
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** Nonn, O; Fischer, C; Geisberger, S; El-Heliebi, A; Kroneis, T; Forstner, D; Desoye, G; Staff, AC; Sugulle, M; Dechend, R; Pecks, U; Kollmann, M; Stern, C; Cartwright, JE; Whitley, GS; Thilaganathan, B; Wadsack, C; Huppertz, B; Herse, F; Gauster, M
MATERNAL ANGIOTENSIN INCREASES PLACENTAL LEPTIN IN EARLY GESTATION VIA AN ALTERNATIVE RAS-PATHWAY - SUGGESTING A LINK TO PRE-ECLAMPSIA
PLACENTA. 2021; 112: E25-E25.-IFPA 2021; AUG 30 - SEP 2, 2021; Amsterdam, Netherlands.
[Onlinepräsentation]
Web of Science
** Smolle, E; Leko, P; Stacher-Priehse, E; Brcic, L; El-Heliebi, A; Hofmann, L; Quehenberger, F; Hrzenjak, A; Popper, H; Olschewski, H; Leithner, K
Expression Pattern and Prognostic Significance of Gluconeogenesis Enzymes in Lung Cancer.
J THORAC ONCOL. 2021; 16(3):S550-S550.
[Poster]
Web of Science
2020
Originalarbeit (Zeitschrift)
** Hofmann, L; Kroneis, T; El-Heliebi, A
Using In Situ Padlock Probe Technology to Detect mRNA Splice Variants in Tumor Cells.
Methods Mol Biol. 2020; 2148: 361-378.
Doi: 10.1007/978-1-0716-0623-0_23
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** Hofmann, L; Sallinger, K; Haudum, C; Smolle, M; Heitzer, E; Moser, T; Novy, M; Gesson, K; Kroneis, T; Bauernhofer, T; El-Heliebi, A
A Multi-Analyte Approach for Improved Sensitivity of Liquid Biopsies in Prostate Cancer.
Cancers (Basel). 2020; 12(8):
Doi: 10.3390/cancers12082247
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** Smolle, E; Leko, P; Stacher-Priehse, E; Brcic, L; El-Heliebi, A; Hofmann, L; Quehenberger, F; Hrzenjak, A; Popper, HH; Olschewski, H; Leithner, K
Distribution and prognostic significance of gluconeogenesis and glycolysis in lung cancer.
Mol Oncol. 2020; 14(11):2853-2867
Doi: 10.1002/1878-0261.12780
[OPEN ACCESS]
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Editorial
** Pot, M; Brehme, M; El-Heliebi, A; Gschmeidler, B; Hofer, P; Kroneis, T; Schirmer, M; Schumann, S; Prainsack, B
Personalized medicine in Austria: expectations and limitations.
Per Med. 2020; 17(6):423-428
Doi: 10.2217/pme-2020-0061
[OPEN ACCESS]
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Abstract (Zeitschrift)
** Smolle, E; Leko, P; Stacher-Priehse, E; Brcic, L; El-Heliebi, A; Hofmann, L; Quehenberger, F; Hrzenjak, A; Popper, H; Olschewski, H; Leithner, K
Distribution and prognostic significance of gluconeogenic and glycolytic phenotypes in non-small cell lung cancer.
WIEN KLIN WOCHENSCHR. 2020; 132(19-20):621-622.-Annual Meeting of the Austrian Society of Pulmonology; OCT 14-16, 2020; virtual.
[Oral Communication]
Web of Science
2019
Originalarbeit (Zeitschrift)
** Chen, S; Tauber, G; Langsenlehner, T; Schmölzer, LM; Pötscher, M; Riethdorf, S; Kuske, A; Leitinger, G; Kashofer, K; Czyż, ZT; Polzer, B; Pantel, K; Sedlmayr, P; Kroneis, T; El-Heliebi, A
In Vivo Detection of Circulating Tumor Cells in High-Risk Non-Metastatic Prostate Cancer Patients Undergoing Radiotherapy.
Cancers (Basel). 2019; 11(7):
Doi: 10.3390/cancers11070933
[OPEN ACCESS]
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** Fuchs, J; Mueller, M; Daxböck, C; Stückler, M; Lang, I; Leitinger, G; Bock, E; El-Heliebi, A; Moser, G; Glasmacher, B; Brislinger, D
Histological processing of un-/cellularized thermosensitive electrospun scaffolds.
Histochem Cell Biol. 2019; 151(4):343-356
Doi: 10.1007/s00418-018-1757-7
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Abstract (Zeitschrift)
** Nonn, O; Maninger, S; El-Heliebi, A; Kroneis, T; Forstner, D; Guettler, J; Siwetz, M; Herse, F; Hiden, U; Hoch, D; Desoye, G; Huppertz, B; Gauster, M
ANGIOTENSIN II UPREGULATES PLACENTAL LEPTIN AND HAS A POTENTIAL INFLAMMATORY ROLE IN EARLY GESTATION PLACENTA
PLACENTA. 2019; 83: E33-E33.-Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 21-24, 2018; Tokyo, JAPAN.
Doi: 10.1016/j.placenta.2019.06.110
[Poster]
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2018
Originalarbeit (Zeitschrift)
** Chen, S; El-Heliebi, A; Schmid, J; Kashofer, K; Czyż, ZT; Polzer, BM; Pantel, K; Kroneis, T; Sedlmayr, P
Target Cell Pre-enrichment and Whole Genome Amplification for Single Cell Downstream Characterization.
J Vis Exp. 2018; (135):
Doi: 10.3791/56394
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** El-Heliebi, A; Hille, C; Laxman, N; Svedlund, J; Haudum, C; Ercan, E; Kroneis, T; Chen, S; Smolle, M; Rossmann, C; Krzywkowski, T; Ahlford, A; Darai, E; von Amsberg, G; Alsdorf, W; König, F; Löhr, M; de Kruijff, I; Riethdorf, S; Gorges, TM; Pantel, K; Bauernhofer, T; Nilsson, M; Sedlmayr, P
In Situ Detection and Quantification of AR-V7, AR-FL, PSA, and KRAS Point Mutations in Circulating Tumor Cells.
Clin Chem. 2018; 64(3):536-546
Doi: 10.1373/clinchem.2017.281295
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** Gauster, M; Maninger, S; Siwetz, M; Deutsch, A; El-Heliebi, A; Kolb-Lenz, D; Hiden, U; Desoye, G; Herse, F; Prokesch, A
Downregulation of p53 drives autophagy during human trophoblast differentiation.
Cell Mol Life Sci. 2018; 75(10):1839-1855
Doi: 10.1007/s00018-017-2695-6
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** Graupp, M; Rinner, B; Frisch, MT; Weiss, G; Fuchs, J; Sundl, M; El-Heliebi, A; Moser, G; Kamolz, LP; Karbiener, M; Gugatschka, M
Towards an in vitro fibrogenesis model of human vocal fold scarring.
Eur Arch Otorhinolaryngol. 2018; 275(5):1211-1218
Doi: 10.1007/s00405-018-4922-7
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** Ståhlberg, A; El-Heliebi, A; Sedlmayr, P; Kroneis, T
Unravelling the biological secrets of microchimerism by single-cell analysis.
Brief Funct Genomics. 2018; 17(4):255-264
Doi: 10.1093/bfgp/elx027
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Abstract (Zeitschrift)
** Nonn, O; Maninger, S; El-Heliebi, A; Kroneis, T; Forstner, D; Siwetz, M; Herse, F; Hoch, D; Desoye, G; Pecks, U; Huppertz, B; Gauster, M
OXYGEN AS POSSIBLE REGULATOR OF EARLY GESTATION ANGIOTENSIN II TYPE 1 RECEPTOR AND ITS LOCALISATION SHOWN BY IN SITU HYBRIDISATION BASED PADLOCK-PROBE TECHNOLOGY AT PLACENTAL ENDOTHELIUM
PLACENTA. 2018; 69: E78-E78.-Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 21-24, 2018; Tokyo, JAPAN.
[Poster]
Web of Science
2017
Originalarbeit (Zeitschrift)
** Chen, S; El-Heliebi, A; Kroneis, T
Biological and Molecular Characterization of Circulating Tumor Cells: A Creative Strategy for Precision Medicine?
Adv Clin Chem. 2017; 82(6):71-103
Doi: 10.1016/bs.acc.2017.06.001
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** Chen, S; El-Heliebi, A; Tauber, G; Langsenlehner, T; Pötscher, M; Kashofer, K; Czyż, ZT; Polzer, B; Riethdorf, S; Kuske, A; Leitinger, G; Pantel, K; Kroneis, T; Sedlmayr, P
Catch and Release: rare cell analysis from a functionalised medical wire.
Sci Rep. 2017; 7(2):43424-43424
Doi: 10.1038/srep43424
[OPEN ACCESS]
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** El-Heliebi, A; Kashofer, K; Fuchs, J; Jahn, SW; Viertler, C; Matak, A; Sedlmayr, P; Hoefler, G
Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer.
Histochem Cell Biol. 2017; 148(2):105-115
Doi: 10.1007/s00418-017-1557-5
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** Golob-Schwarzl, N; Schweiger, C; Koller, C; Krassnig, S; Gogg-Kamerer, M; Gantenbein, N; Toeglhofer, AM; Wodlej, C; Bergler, H; Pertschy, B; Uranitsch, S; Holter, M; El-Heliebi, A; Fuchs, J; Punschart, A; Stiegler, P; Keil, M; Hoffmann, J; Henderson, D; Lehrach, H; Reinhard, C; Regenbrecht, C; Schicho, R; Fickert, P; Lax, S; Haybaeck, J
Separation of low and high grade colon and rectum carcinoma by eukaryotic translation initiation factors 1, 5 and 6.
Oncotarget. 2017; 8(60):101224-101243
Doi: 10.18632/oncotarget.20642
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** Holland, O; Kroneis, T; El-Heliebi, A; McDowell-Hook, M; Stone, P; Sedlmayr, P; Chamley, L
Detection of Fetal Sex, Aneuploidy and a Microdeletion from Single Placental Syncytial Nuclear Aggregates.
Fetal Diagn Ther. 2017; 41(1):32-40
Doi: 10.1159/000445112
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Abstract (Zeitschrift)
** Golob-Schwarzl, N; Koller, C; Krassnig, S; Gogg-Kammerer, M; Gantenbein, N; Bergler, H; Pertschy, B; Uranitsch, S; Holter, M; El-Heliebi, A; Fuchs, J; Punschart, A; Stiegler, P; Keil, M; Hoffmann, J; Henderson, D; Lehrach, H; Reinhard, C; Schicho, R; Fickert, P; Lax, S; Haybaeck, J
Translation initiation separates low and high grade and colon and rectum carcinoma
VIRCHOWS ARCH. 2017; 471: S167-S167.
[Poster]
Web of Science
2016
Originalarbeit (Zeitschrift)
** Kammerer, S; Sokolowski, A; Hackl, H; Platzer, D; Jahn, SW; El-Heliebi, A; Schwarzenbacher, D; Stiegelbauer, V; Pichler, M; Rezania, S; Fiegl, H; Peintinger, F; Regitnig, P; Hoefler, G; Schreibmayer, W; Bauernhofer, T
KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients.
Oncotarget. 2016; 7(51):84705-84717
Doi: 10.18632/oncotarget.13224
[OPEN ACCESS]
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** Kargl, J; Andersen, L; Hasenöhrl, C; Feuersinger, D; Stančić, A; Fauland, A; Magnes, C; El-Heliebi, A; Lax, S; Uranitsch, S; Haybaeck, J; Heinemann, A; Schicho, R
GPR55 promotes migration and adhesion of colon cancer cells indicating a role in metastasis.
Br J Pharmacol. 2016; 173(1):142-154
Doi: 10.1111/bph.13345
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** Siwetz, M; Blaschitz, A; El-Heliebi, A; Hiden, U; Desoye, G; Huppertz, B; Gauster, M
TNF-α alters the inflammatory secretion profile of human first trimester placenta.
Lab Invest. 2016; 96(4):428-438
Doi: 10.1038/labinvest.2015.159
[OPEN ACCESS]
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2015
Originalarbeit (Zeitschrift)
** El-Heliebi, A; Chen, S; Kroneis, T
Using Multiplex PCR for Assessing the Quality of Whole Genome Amplified DNA.
Methods Mol Biol. 2015; 1347(22):119-128
Doi: 10.1007/978-1-4939-2990-0_9
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** El-Heliebi, A; Chen, S; Kroneis, T
Heat-Induced Fragmentation and Adapter-Assisted Whole Genome Amplification Using GenomePlex® Single-Cell Whole Genome Amplification Kit (WGA4).
Methods Mol Biol. 2015; 1347(22):101-109
Doi: 10.1007/978-1-4939-2990-0_7
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** Kroneis, T; Chen, S; El-Heliebi, A
Low-Volume On-Chip Single-Cell Whole Genome Amplification for Multiple Subsequent Analyses.
Methods Mol Biol. 2015; 1347(22):245-261
Doi: 10.1007/978-1-4939-2990-0_17
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** Kroneis, T; El-Heliebi, A
Whole Genome Amplification by Isothermal Multiple Strand Displacement Using Phi29 DNA Polymerase.
Methods Mol Biol. 2015; 1347(22):111-117
Doi: 10.1007/978-1-4939-2990-0_8
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** Kroneis, T; El-Heliebi, A
Quality Control of Isothermal Amplified DNA Based on Short Tandem Repeat Analysis.
Methods Mol Biol. 2015; 1347(22):129-140
Doi: 10.1007/978-1-4939-2990-0_10
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** Kroneis, T; El-Heliebi, A
Whole Genome Amplification of Labeled Viable Single Cells Suited for Array-Comparative Genomic Hybridization.
Methods Mol Biol. 2015; 1347(22):233-243
Doi: 10.1007/978-1-4939-2990-0_16
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Abstract (Zeitschrift)
** Orthmann, A; Hoffmann, A; Zeisig, R; EL-Heliebi, A; Ernst, C; Hayback, J; Jodicke, A; Kuhn, S; Linnebacher, M; Hoffmann, J; Fichtner, I
Therapeutic response to bevacicumab, irinotecan, and temozolomide of PDX from human glioma cannot be correlated to common mutations as routinely identified by panel sequencing
CANCER RES. 2015; 75:
Doi: 10.1158/1538-7445.BRAIN15-B24
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** Siwetz, M; El-Heliebi, A; Blaschitz, A; Hiden, U; Desoye, G; Huppertz, B; Gauster, M
TNF-alpha UPREGULATES SECRETION OF GM-CSF, CCL5 AND IL-10 BY HUMAN FIRST TRIMESTER PLACENTA
PLACENTA. 2015; 36(9):A23-A23.
Doi: 10.1016/j.placenta.2015.07.254
[Poster]
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2014
Originalarbeit (Zeitschrift)
** El-Heliebi, A; Kroneis, T; Wagner, K; Meditz, K; Kolb, D; Feichtinger, J; Thallinger, GG; Quehenberger, F; Liegl-Atzwanger, B; Rinner, B
Resolving tumor heterogeneity: genes involved in chordoma cell development identified by low-template analysis of morphologically distinct cells.
PLoS One. 2014; 9(2):e87663-e87663
Doi: 10.1371/journal.pone.0087663
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** Kolb, D; Pritz, E; Steinecker-Frohnwieser, B; Lohberger, B; Deutsch, A; Kroneis, T; El-Heliebi, A; Dohr, G; Meditz, K; Wagner, K; Koefeler, H; Leitinger, G; Leithner, A; Liegl-Atzwanger, B; Zweytick, D; Rinner, B
Extended ultrastructural characterization of chordoma cells: the link to new therapeutic options.
PLoS One. 2014; 9(12):e114251
Doi: 10.1371/journal.pone.0114251
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** Kucukoglu, O; Guldiken, N; Chen, Y; Usachov, V; El-Heliebi, A; Haybaeck, J; Denk, H; Trautwein, C; Strnad, P
High-fat diet triggers Mallory-Denk body formation through misfolding and crosslinking of excess keratin 8.
Hepatology. 2014; 60(1):169-178
Doi: 10.1002/hep.27068
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Abstract (Zeitschrift)
** Rinner, B; El-Heliebi, A; Kroneis, T; Wagner, K; Kolb, D; Feichtinger, J; Thallinger, G; Quehenberger, F; Leithner, A; Scheipl, S; Liegl-Atzwanger, B
Heterogeneity of Chordoma cells
VIRCHOWS ARCH. 2014; 465: S17-S17.
[Poster]
Web of Science
** Rivera, M; Keil, M; Boehnke, K; Lange, M; Schumacher, D; Schafer, R; Regenbrecht, CR; Henderson, D; Keilholz, U; Kuehn, A; El-Heliebi, A; Hohensee, T; Hayback, J; Reinhard, C; Velasco, JA; Lehrach, H; Garin-Chesa, P; Beran, G; Hoffmann, J
Generation of drug response data from 57 new patient-derived colon cancer xenografts and 3D cell cultures for systematic correlation with tumor biology within the OncoTrack* project
CANCER RES. 2014; 74(19):
Doi: 10.1158/1538-7445.AM2014-2978
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2013
Originalarbeit (Zeitschrift)
** El-Heliebi, A; Kroneis, T; Zöhrer, E; Haybaeck, J; Fischereder, K; Kampel-Kettner, K; Zigeuner, R; Pock, H; Riedl, R; Stauber, R; Geigl, JB; Huppertz, B; Sedlmayr, P; Lackner, C
Are morphological criteria sufficient for the identification of circulating tumor cells in renal cancer?
J Transl Med. 2013; 11(10):214-214
Doi: 10.1186/1479-5876-11-214
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** Feichtinger, J; El-Heliebi, A; Kroneis, T; Wagner, K; Liegl-Atzwanger, B; Leithner, A; Thallinger, GG; Rinner, B
Chordoma Low-Template Microarray Analysis.
Biomed Tech (Berl). 2013; 58 Suppl 1:
Doi: 10.1515/bmt-2013-4310
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2011
Originalarbeit (Zeitschrift)
** Kroneis, T; Geigl, JB; El-Heliebi, A; Auer, M; Ulz, P; Schwarzbraun, T; Dohr, G; Sedlmayr, P
Combined molecular genetic and cytogenetic analysis from single cells after isothermal whole-genome amplification.
Clin Chem. 2011; 57(7):1032-1041
Doi: 10.1373/clinchem.2011.162131
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