Medizinische Universität Graz - Research portal
Fröhlich Leopold F. |
** = Publications listed in SCI/SSCI/Pubmed
2020
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** Golob-Schwarzl, N; Bettermann, K; Mehta, AK; Kessler, SM; Unterluggauer, J; Krassnig, S; Kojima, K; Chen, X; Hoshida, Y; Bardeesy, NM; Müller, H; Svendova, V; Schimek, MG; Diwoky, C; Lipfert, A; Mahajan, V; Stumptner, C; Thüringer, A; Fröhlich, LF; Stojakovic, T; Nilsson, KPR; Kolbe, T; Rülicke, T; Magin, TM; Strnad, P; Kiemer, AK; Moriggl, R; Haybaeck, J
Corrigendum to High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype12 [Translational Oncology Volume 12, Issue 2, February 2019, Pages 256-268].
Transl Oncol. 2020; 13(2):490-492
Doi: 10.1016/j.tranon.2019.08.001
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2019
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** Golob-Schwarzl, N; Bettermann, K; Mehta, AK; Kessler, SM; Unterluggauer, J; Krassnig, S; Kojima, K; Chen, X; Hoshida, Y; Bardeesy, NM; Müller, H; Svendova, V; Schimek, MG; Diwoky, C; Lipfert, A; Mahajan, V; Stumptner, C; Thüringer, A; Fröhlich, LF; Stojakovic, T; Nilsson, KPR; Kolbe, T; Rülicke, T; Magin, TM; Strnad, P; Kiemer, AK; Moriggl, R; Haybaeck, J
High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype.
Transl Oncol. 2019; 12(2):256-268
Doi: 10.1016/j.tranon.2018.10.010
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2016
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** Fröhlich, LF; Mrakovcic, M; Smole, C; Zatloukal, K
Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway.
Cancer Cell Int. 2016; 16(1):68-68
Doi: 10.1186/s12935-016-0343-0
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** Lahiri, P; Schmidt, V; Smole, C; Kufferath, I; Denk, H; Strnad, P; Rülicke, T; Fröhlich, LF; Zatloukal, K
p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies.
PLoS One. 2016; 11(8):e0161083-e0161083
Doi: 10.1371/journal.pone.0161083
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** Yang, H; Ni, HM; Guo, F; Ding, Y; Shi, YH; Lahiri, P; Fröhlich, LF; Rülicke, T; Smole, C; Schmidt, VC; Zatloukal, K; Cui, Y; Komatsu, M; Fan, J; Ding, WX
Sequestosome 1/p62 Protein Is Associated with Autophagic Removal of Excess Hepatic Endoplasmic Reticulum in Mice.
J Biol Chem. 2016; 291(36):18663-18674
Doi: 10.1074/jbc.M116.739821
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2014
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** Fröhlich, LF; Mrakovcic, M; Smole, C; Lahiri, P; Zatloukal, K
Epigenetic silencing of apoptosis-inducing gene expression can be efficiently overcome by combined SAHA and TRAIL treatment in uterine sarcoma cells.
PLoS One. 2014; 9(3):e91558-e91558
Doi: 10.1371/journal.pone.0091558
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2013
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** Mrakovcic, M; Absenger, M; Riedl, R; Smole, C; Roblegg, E; Fröhlich, LF; Fröhlich, E
Assessment of long-term effects of nanoparticles in a microcarrier cell culture system.
PLoS One. 2013; 8(2):e56791-e56791
Doi: 10.1371/journal.pone.0056791
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** Schughart, K; Libert, C; SYSGENET consortium; Kas, MJ
Controlling complexity: the clinical relevance of mouse complex genetics.
Eur J Hum Genet. 2013; 21(11):1191-1196
Doi: 10.1038/ejhg.2013.79
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2012
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** Fernández-Rebollo, E; Maeda, A; Reyes, M; Turan, S; Fröhlich, LF; Plagge, A; Kelsey, G; Jüppner, H; Bastepe, M
Loss of XLαs (extra-large αs) imprinting results in early postnatal hypoglycemia and lethality in a mouse model of pseudohypoparathyroidism Ib.
Proc Natl Acad Sci U S A. 2012; 109(17):6638-6643
Doi: 10.1073/pnas.1117608109
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** Senanayake, U; Das, S; Vesely, P; Alzoughbi, W; Fröhlich, LF; Chowdhury, P; Leuschner, I; Hoefler, G; Guertl, B
miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms.
Carcinogenesis. 2012; 33(5):1014-1021
Doi: 10.1093/carcin/bgs126
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2011
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** Liu, Z; Segawa, H; Aydin, C; Reyes, M; Erben, RG; Weinstein, LS; Chen, M; Marshansky, V; Fröhlich, LF; Bastepe, M
Transgenic overexpression of the extra-large Gsα variant XLαs enhances Gsα-mediated responses in the mouse renal proximal tubule in vivo.
Endocrinology. 2011; 152(4):1222-1233
Doi: 10.1210/en.2010-1034
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** Motta, JP; Magne, L; Descamps, D; Rolland, C; Squarzoni-Dale, C; Rousset, P; Martin, L; Cenac, N; Balloy, V; Huerre, M; Fröhlich, LF; Jenne, D; Wartelle, J; Belaaouaj, A; Mas, E; Vinel, JP; Alric, L; Chignard, M; Vergnolle, N; Sallenave, JM
Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.
Gastroenterology. 2011; 140(4): 1272-1282.
Doi: 10.1053/j.gastro.2010.12.050
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2010
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** Fröhlich, LF; Mrakovcic, M; Steinborn, R; Chung, UI; Bastepe, M; Jüppner, H
Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib.
Proc Natl Acad Sci U S A. 2010; 107(20): 9275-9280.
Doi: 10.1073/pnas.0910224107
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2008
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** Kessenbrock, K; Fröhlich, L; Sixt, M; Lämmermann, T; Pfister, H; Bateman, A; Belaaouaj, A; Ring, J; Ollert, M; Fässler, R; Jenne, DE
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin.
J Clin Invest. 2008; 118(7): 2438-2447.
Doi: 10.1172/JCI34694
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2007
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** Fröhlich, LF; Bastepe, M; Ozturk, D; Abu-Zahra, H; Jüppner, H
Lack of Gnas epigenetic changes and pseudohypoparathyroidism type Ib in mice with targeted disruption of syntaxin-16.
Endocrinology. 2007; 148(6): 2925-2935.
Doi: 10.1210/en.2006-1298
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** Hesse, M; Fröhlich, LF; Zeitz, U; Lanske, B; Erben, RG
Ablation of vitamin D signaling rescues bone, mineral, and glucose homeostasis in Fgf-23 deficient mice.
Matrix Biol. 2007; 26(2): 75-84.
Doi: 10.1016/j.matbio.2006.10.003
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2006
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** Bounoutas, GS; Tawfeek, H; Fröhlich, LF; Chung, UI; Abou-Samra, AB
Impact of impaired receptor internalization on calcium homeostasis in knock-in mice expressing a phosphorylation-deficient parathyroid hormone (PTH)/PTH-related peptide receptor.
Endocrinology. 2006; 147(10): 4674-4679.
Doi: 10.1210/en.2006-0301
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** Juppner, H; Linglart, A; Frohlich, LF; Bastepe, M
Autosomal-dominant pseudohypoparathyroidism type Ib is caused by different microdeletions within or upstream of the GNAS locus
ANN N Y ACAD SCI. 2006; 1068(10): 250-255.
Doi: 10.1196/annals.1346.029
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2005
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** Bastepe, M; Fröhlich, LF; Linglart, A; Abu-Zahra, HS; Tojo, K; Ward, LM; Jüppner, H
Deletion of the NESP55 differentially methylated region causes loss of maternal GNAS imprints and pseudohypoparathyroidism type Ib.
Nat Genet. 2005; 37(1): 25-27.
Doi: 10.1038/ng1487
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2004
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** Fröhlich, LF; Gensure, RC; Schipani, E; Jüppner, H; Bastepe, M
Haplotype frequencies and linkage disequilibrium analysis of four frequent polymorphisms at the PTH/PTH-related peptide receptor gene locus.
Mol Cell Probes. 2004; 18(5): 353-357.
Doi: 10.1016/j.mcp.2004.05.005
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** Pfister, H; Ollert, M; Fröhlich, LF; Quintanilla-Martinez, L; Colby, TV; Specks, U; Jenne, DE
Antineutrophil cytoplasmic autoantibodies against the murine homolog of proteinase 3 (Wegener autoantigen) are pathogenic in vivo.
Blood. 2004; 104(5): 1411-1418.
Doi: 10.1182/blood-2004-01-0267
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2003
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** Bastepe, M; Fröhlich, LF; Hendy, GN; Indridason, OS; Josse, RG; Koshiyama, H; Körkkö, J; Nakamoto, JM; Rosenbloom, AL; Slyper, AH; Sugimoto, T; Tsatsoulis, A; Crawford, JD; Jüppner, H
Autosomal dominant pseudohypoparathyroidism type Ib is associated with a heterozygous microdeletion that likely disrupts a putative imprinting control element of GNAS.
J Clin Invest. 2003; 112(8): 1255-1263.
Doi: 10.1172/JCI19159
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2002
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** Fröhlich, L; Liu, Z; Beier, DR; Lanske, B
Genomic structure and refined chromosomal localization of the mouse Ptch2 gene.
Cytogenet Genome Res. 2002; 97(1-2): 106-110.
Doi: 10.1159/000064064
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1997
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** Jenne, DE; Fröhlich, L; Hummel, AM; Specks, U
Cloning and functional expression of the murine homologue of proteinase 3: implications for the design of murine models of vasculitis.
FEBS Lett. 1997; 408(2):187-190
Doi: 10.1016/S0014-5793(97)00418-3
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** Rauch, U; Clement, A; Retzler, C; Fröhlich, L; Fässler, R; Göhring, W; Faissner, A
Mapping of a defined neurocan binding site to distinct domains of tenascin-C.
J Biol Chem. 1997; 272(43):26905-26912
Doi: 10.1074/jbc.272.43.26905
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1996
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** Forsberg, E; Hirsch, E; Fröhlich, L; Meyer, M; Ekblom, P; Aszodi, A; Werner, S; Fässler, R
Skin wounds and severed nerves heal normally in mice lacking tenascin-C.
Proc Natl Acad Sci U S A. 1996; 93(13):6594-6599
Doi: 10.1073/pnas.93.13.6594
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