Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Fuchs Claudia |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2025
Originalarbeit (Zeitschrift)
** Dixon, ED; Claudel, T; Nardo, AD; Riva, A; Fuchs, CD; Mlitz, V; Busslinger, G; Scharnagl, H; Stojakovic, T; Senéca, J; Hinteregger, H; Grabner, GF; Kratky, D; Verkade, H; Zimmermann, R; Haemmerle, G; Trauner, M
Inhibition of ATGL alleviates MASH via impaired PPARα signalling that favours hydrophilic bile acid composition in mice.
J Hepatol. 2024;
Doi: 10.1016/j.jhep.2024.09.037
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2024
Abstract (Zeitschrift)
** Fuchs, C; Petrenko, O; Mlitz, V; Scharnagl, H; Stojakovic, T; Reiberger, T; Garfinkel, B; Trauner, M
Inhibition of bile acid conjugation improves DDC-induced cholestatic liver injury in mice with a humanized bile acid pool
J HEPATOL. Abstracts. 2024; 80: S296-S296.-EASL Congress; JUN 5-8, 2024; Milan, ITALY.
[Poster]
Web of Science
2023
Originalarbeit (Zeitschrift)
** Chalhoub, G; Jamnik, A; Pajed, L; Kolleritsch, S; Hois, V; Bagaric, A; Prem, D; Tilp, A; Kolb, D; Wolinski, H; Taschler, U; Zullig, T; Rechberger, GN; Fuchs, C; Trauner, M; Schoiswohl, G; Haemmerle, G
Carboxylesterase 2a deletion provokes hepatic steatosis and insulin resistance in mice involving impaired diacylglycerol and lysophosphatidylcholine catabolism
MOL METAB. 2023; 72: 101725
Doi: 10.1016/j.molmet.2023.101725
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** Fuchs, CD; Claudel, T; Mlitz, V; Riva, A; Menz, M; Brusilovskaya, K; Haller, F; Baumgartner, M; Königshofer, P; Unger, LW; Sjöland, W; Scharnagl, H; Stojakovic, T; Busslinger, G; Reiberger, T; Marschall, HU; Trauner, M
GLP-2 Improves Hepatic Inflammation and Fibrosis in Mdr2-/- Mice Via Activation of NR4a1/Nur77 in Hepatic Stellate Cells and Intestinal FXR Signaling.
Cell Mol Gastroenterol Hepatol. 2023; 16(5):847-856
Doi: 10.1016/j.jcmgh.2023.08.003
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** Fuchs, CD; Sroda, N; Scharnagl, H; Gupta, R; Minto, W; Stojakovic, T; Liles, JT; Budas, G; Hollenback, D; Trauner, M
Non-steroidal FXR agonist cilofexor improves cholestatic liver injury in the Mdr2-/- mouse model of sclerosing cholangitis.
JHEP Rep. 2023; 5(11):100874
Doi: 10.1016/j.jhepr.2023.100874
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** Macháček, T; Fuchs, CD; Winkelmann, F; Frank, M; Scharnagl, H; Stojakovic, T; Sombetzki, M; Trauner, M
Bsep/Abcb11 knockout ameliorates Schistosoma mansoni liver pathology by reducing parasite fecundity.
Liver Int. 2023; 43(11):2469-2478
Doi: 10.1111/liv.15710
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2022
Originalarbeit (Zeitschrift)
** Remetic, J; Ghallab, A; Hobloss, Z; Brackhagen, L; Hassan, R; Myllys, M; Radun, R; Mlitz, V; Zhu, C; Baumgartner, M; Schrottmaier, WC; Mussbacher, M; Timelthaler, G; Scharnagl, H; Stojakovic, T; Assinger, A; Fuchs, CD; Hengstler, JG; Trauner, M
Loss of bile salt export pump aggravates lipopolysaccharide-induced liver injury in mice due to impaired hepatic endotoxin clearance.
Hepatology. 2021;
Doi: 10.1002/hep.32289
[OPEN ACCESS]
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Abstract (Zeitschrift)
** Dixon, ED; Nardo, AD; Claudel, T; Fuchs, C; Mlitz, V; Stojakovic, T; Scharnagl, H; Grabner, G; Zimmermann, R; Trauner, M
Chemical suppression of adipose triglyceride lipase improves non-alcoholic steatohepatitis in a diabetic and hyperlipidemic mouse model
J HEPATOL. 2022; 77: S688-S689.
[Poster]
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** Fuchs, C; Dixon, ED; Konigshofer, P; Mlitz, V; Scharnagl, H; Stojakovic, T; Reiberger, T; Trauner, M
Loss of bile salt export pump (BSEP/ABCB11) protects mice from development of carbon tetrachloride (CCl4) induced hepatic fibrosis
J HEPATOL. 2022; 77: S469-S469.
[Poster]
Web of Science
2021
Originalarbeit (Zeitschrift)
** Tardelli, M; Bruschi, FV; Fuchs, CD; Claudel, T; Auer, N; Kunczer, V; Ronda, OAHO; Verkade, HJ; Stojakovic, T; Scharnagl, H; Trauner, M
Absence of Adiponutrin (PNPLA3) and Monoacylglycerol Lipase Synergistically Increases Weight Gain and Aggravates Steatohepatitis in Mice.
Int J Mol Sci. 2021; 22(4):
Doi: 10.3390/ijms22042126
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2019
Originalarbeit (Zeitschrift)
** Tardelli, M; Bruschi, FV; Claudel, T; Fuchs, CD; Auer, N; Kunczer, V; Stojakovic, T; Scharnagl, H; Habib, A; Grabner, GF; Zimmermann, R; Lotersztajn, S; Trauner, M
Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption.
J Lipid Res. 2019; 60(7):1284-1292
Doi: 10.1194/jlr.M093369
[OPEN ACCESS]
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Abstract (Zeitschrift)
** Menz, M; Hinterleitner, L; Konigshofer, P; Halilbasic, E; Kunczer, V; Stojakovic, T; Reiberger, T; Fuchs, C; Trauner, M
Glucagon like peptide-2 treatment improves liver and bile duct injury in the Mdr2-/- mouse model of sclerosing cholangitis
J HEPATOL. 2019; 70: E167-E168.
Doi: 10.1016/S0618-8278(19)30301-9
[Poster]
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** Remetic, J; Mlitz, V; Kunczer, V; Schargl, H; Stojakovic, T; Fuchs, C; Trauner, M
Loss of bile salt export pump (Bsep/Abcb11) aggravates lipopolysaccharide induced hepatic inflammation in mice
J HEPATOL. 2019; 70: E169-E169.
Doi: 10.1016/S0618-8278(19)30305-6
[Poster]
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** Zhu, C; Boucheron, N; Muller, A; Majek, P; Fuchs, C; Baazim, H; Lercher, A; Halilbasic, E; Gulich, A; Sakaguchi, S; Sandner, L; Stojakovic, T; Scharnagl, H; Bergthaler, A; Ellmeier, W; Trauner, M
24-nor-ursodeoxycholic acid ameliorates inflammation by reshaping mTOR proteome and immunometabolism sensing programs in CD8 T cells
EUR J IMMUNOL. 2019; 49: 1282-1282.-17th International Congress of Immunology (IUIS); OCT 19-23, 2019; Beijing, PEOPLES R CHINA.
[Poster]
Web of Science
2018
Abstract (Zeitschrift)
** Fuchs, C; Paumgartner, G; Mlitz, V; Wolfrum, S; Wahlstrom, A; Stahlman, M; Stojakovic, T; Wolfrum, C; Marschall, HU; Trauner, M
Loss of BSEP protects MDR2/ABCB4 KO mice from cholestatic liver injury by altering bile acid profile and signaling
J HEPATOL. 2018; 68: S449-S450.
Doi: 10.1016/S0168-8278(18)31141-3
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2016
Abstract (Zeitschrift)
** Lemberger, U; Fuchs, C; Karer, M; Stojakovic, T; Meier, S; Schofer, C; Egger, G; Wrba, F; Gerner, C; Taketo, M; Trauner, M; Oesterreicher, CH;
HEPATOCYTE SPECIFIC EXPRESSION OF A DOMINANT STABLE FORM OF B-CATENIN RESULTS IN EARLY LETHALITY DUE TO DISTURBANCES IN LIPID AND GLUCOSE METABOLISM.
J HEPATOL. JOURNAL OF HEPATOLOGY64: S687-S687. AMSTERDAM: ELSEVIER SCIENCE BV; ( Presented at: EASL International Liver Congress, Barcelona, SPAIN, APR 13-17, 2016)
Doi: 10.1016/S0168-8278(16)01309-X
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2015
Übersichtsarbeit
** Trauner, M; Halilbasic, E; Claudel, T; Steinacher, D; Fuchs, C; Moustafa, T; Pollheimer, M; Krones, E; Kienbacher, C; Traussnigg, S; Kazemi-Shirazi, L; Munda, P; Hofer, H; Fickert, P; Paumgartner, G
Potential of nor-Ursodeoxycholic Acid in Cholestatic and Metabolic Disorders.
Dig Dis. 2015; 33(3):433-439
Doi: 10.1159/000371904
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Abstract (Zeitschrift)
** Fuchs, CD; Claudel, T; Halilbasic, E; Jha, P; Spindelboeck, W; Stojakovic, T; Trauner, M
ROLE OF FXR CONTROLLED Chop IN MEDIATING BILE ACID EFFECTS IN NAFLD.
J HEPATOL. 2015; 62(S2):S689-S689.-50th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 22-26, 2015; Vienna, AUSTRIA.
[Poster]
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** Lemberger, UJ; Fuchs, C; Karer, M; Schöfer, C; Stojakovic, T; Wrba, F; Taketo, MM; Trauner, M; Österreicher, CH
HEPATOCYTE SPECIFIC EXPRESSION OF A DOMINANT STABLE FORM OF BETA-CATENIN RESULTS IN CHOLESTATIC LIVER DISEASE.
J HEPATOL. 2015; 62(S2):S781-S781.-50th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 22-26, 2015; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(15)31341-6
[Poster]
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2014
Abstract (Zeitschrift)
** Fuchs, CD; Paumgartner, G; Wahlstrom, A; Chiba, P; Stojakovic, T; Claudel, T; Marschall, HU; Trauner, M
Absence of BSEP/ABCB11 protects from cholestatic liver injury in mice.
HEPATOLOGY. 2014; 60: 405A-406A.-65th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 07-11, 2014; Boston, USA.
[Poster]
Web of Science
2013
Übersichtsarbeit
** Fuchs, C; Claudel, T; Trauner, M
Bile acid-mediated control of liver triglycerides.
Semin Liver Dis. 2013; 33(4):330-342
Doi: 10.1055/s-0033-1358520
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Abstract (Zeitschrift)
** Bettermann, K; Mehta, AK; Lederer, E; Ernst, C; Kessler, SM; Chen, X; Hoshida, Y; Bardeesy, N; Fuchs, BC; Tanabe, KK; Müller, H; Svendova, V; Schimek, MG; Mach, M; Speicher, MR; Mahajan, V; Stumptner, C; Thueringer, A; Stojakovic, T; Longerich, T; Schirmacher, P; Magin, TM; Strnad, P; Fuchs, CD; Trauner, M; Spilka, R; Kiemer, AK; Teufel, A; Maass, T; Moriggl, R; Campbell, JS; Thorgeirsson, SS; Stauffer, J; Karin, M; Llovet, JM; Zatloukal, K; Lackner, C; Haybäck, J
Steatohepatitis-associated Hepatocellular Carcinoma: Evidence of a Keratinopathy.
HEPATOLOGY. 2013; 58(S1):543A-543A.-64th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 1-5, 2013; Washington, DC, USA.
[Poster]
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** Fuchs, CD; Claudel, T; Halilbasic, E; Jha, P; Spindelboeck, W; Stojakovic, T; Trauner, M
FXR controlled CHOP as novel key player in NAFLD progression.
HEPATOLOGY. 2013; 58(S1):542A-542A.-64th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 1-5, 2013; Washington, DC, USA.
[Poster]
Web of Science
** Fuchs, CD; Claudel, T; Halilbasic, E; Stojakovic, T; Trauner, M
INTRAHEPATIC CHANGES IN BILE ACID COMPOSITION PROTECTS BSEP (ABCB11) KO MICE FROM HEPATIC INFLAMMATION IN METHIONINE CHOLINE DEFICIENT DIET INDUCED NASH.
J HEPATOL. 2013; 58(S1):S32-S32.-48th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 24-28, 2013; Amsterdam, THE NETHERLANDS.
Doi: 10.1016/S0168-8278(13)60072-0
[Oral Communication]
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2012
Originalarbeit (Zeitschrift)
** Fuchs, CD; Claudel, T; Kumari, P; Haemmerle, G; Pollheimer, MJ; Stojakovic, T; Scharnagl, H; Halilbasic, E; Gumhold, J; Silbert, D; Koefeler, H; Trauner, M
Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice.
Hepatology. 2012; 56(1):270-280
Doi: 10.1002/hep.25601
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Abstract (Zeitschrift)
** Fuchs, C; Claudel, T; Kumari, P; Stojakovic, T; Halilbasic, E; Spindelboeck, W; Gonzalez, F; Trauner, M
FXR IS A KEY PLAYER IN NAFLD DEVELOPMENT BY CONTROLLING CHOP EXPRESSION.
J HEPATOL. 2012; 56(S2):S490-S490.-47th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN.
Doi: 10.1016/S0168-8278(12)61248-3
[Poster]
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2011
Abstract (Zeitschrift)
** Fuchs, CD; Claudel, T; Kumari, P; Stojakovic, T; Haemmerle, G; Halilbasic, E; Gumhold, J; Silbert, D; Koefeler, H; Zechner, R; Trauner, M
ATGL (PNPLA2) KNOCKOUT MICE ARE PROTECTED FROM HEPATIC ER-STRESS VIA OLEIC ACID ACCUMULATION.
J HEPATOL. 2011; 54: S41-S42.-46th Annual Meeting of the European Association for the Study of the Liver (EASL); MAR 30-APR 3, 2011; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(11)60095-0
[Poster]
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** Fuchs, CD; Claudel, T; Stojakovic, T; Silbert, D; Maurer, B; Trauner, M
BSEP (ABCB11) KO MICE ARE PROTECTED FROM HEPATIC INFLAMMATION IN METHIONINE CHOLINE DEFICIENT DIET INDUCED NASH.
HEPATOLOGY. 2011; 54: 1169A-1169A.-62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 04-08, 2011; San Francisco, USA.
[Poster]
Web of Science
2007
Originalarbeit (Zeitschrift)
** Staber, PB; Vesely, P; Haq, N; Ott, RG; Funato, K; Bambach, I; Fuchs, C; Schauer, S; Linkesch, W; Hrzenjak, A; Dirks, WG; Sexl, V; Bergler, H; Kadin, ME; Sternberg, DW; Kenner, L; Hoefler, G
The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling.
Blood. 2007; 110(9):3374-3383
Doi: 10.1182/blood-2007-02-071258
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