Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Chandak Prakash Gopal Das |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2015
Originalarbeit (Zeitschrift)
** Goeritzer, M; Vujic, N; Schlager, S; Chandak, PG; Korbelius, M; Gottschalk, B; Leopold, C; Obrowsky, S; Rainer, S; Doddapattar, P; Aflaki, E; Wegscheider, M; Sachdev, V; Graier, WF; Kolb, D; Radovic, B; Kratky, D
Active autophagy but not lipophagy in macrophages with defective lipolysis.
Biochim Biophys Acta. 2015; 1851(10):1304-1316
Doi: 10.1016/j.bbalip.2015.06.005
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2014
Originalarbeit (Zeitschrift)
** Goeritzer, M; Schlager, S; Radovic, B; Madreiter, CT; Rainer, S; Thomas, G; Lord, CC; Sacks, J; Brown, AL; Vujic, N; Obrowsky, S; Sachdev, V; Kolb, D; Chandak, PG; Graier, WF; Sattler, W; Brown, JM; Kratky, D
Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis.
J Lipid Res. 2014; 55(12):2562-2575
Doi: 10.1194/jlr.M052613
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2013
Originalarbeit (Zeitschrift)
** Doddapattar, P; Radović, B; Patankar, JV; Obrowsky, S; Jandl, K; Nusshold, C; Kolb, D; Vujić, N; Doshi, L; Chandak, PG; Goeritzer, M; Ahammer, H; Hoefler, G; Sattler, W; Kratky, D
Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice.
Mol Nutr Food Res. 2013; 57(10):1718-1728
Doi: 10.1002/mnfr.201200794
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** Obrowsky, S; Chandak, PG; Patankar, JV; Povoden, S; Schlager, S; Kershaw, EE; Bogner-Strauss, JG; Hoefler, G; Levak-Frank, S; Kratky, D
Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling.
J Lipid Res. 2013; 54(2):425-435
Doi: 10.1194/jlr.M031716
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Korrektur
** Aflaki, E; Balenga, NAB; Luschnig-Schratl, P; Wolinski, H; Povoden, S; Chandak, PG; Bogner-Strauss, JG; Eder, S; Konya, V; Kohlwein, SD; Heinemann, A; Kratky, D;
Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis (vol 68, pg 3933, 2011).
CELL MOL LIFE SCI. 2013; 70(14): 2621-2621.
Doi: 10.1007/s00018-013-1371-8
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2011
Originalarbeit (Zeitschrift)
** Aflaki, E; Balenga, NA; Luschnig-Schratl, P; Wolinski, H; Povoden, S; Chandak, PG; Bogner-Strauss, JG; Eder, S; Konya, V; Kohlwein, SD; Heinemann, A; Kratky, D
Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis.
Cell Mol Life Sci. 2011; 68(23): 3933-3947.
Doi: 10.1007/s00018-011-0688-4
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** Aflaki, E; Radovic, B; Chandak, PG; Kolb, D; Eisenberg, T; Ring, J; Fertschai, I; Uellen, A; Wolinski, H; Kohlwein, SD; Zechner, R; Levak-Frank, S; Sattler, W; Graier, WF; Malli, R; Madeo, F; Kratky, D
Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages.
J Biol Chem. 2011; 286(9): 7418-7428.
Doi: 10.1074/jbc.M110.175703
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** Chandak, PG; Obrowsky, S; Radovic, B; Doddapattar, P; Aflaki, E; Kratzer, A; Doshi, LS; Povoden, S; Ahammer, H; Hoefler, G; Levak-Frank, S; Kratky, D
Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice.
Biochim Biophys Acta. 2011; 1811(12): 1011-1020.
Doi: 10.1016/j.bbalip.2011.08.010
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** Lammers, B; Chandak, PG; Aflaki, E; Van Puijvelde, GH; Radovic, B; Hildebrand, RB; Meurs, I; Out, R; Kuiper, J; Van Berkel, TJ; Kolb, D; Haemmerle, G; Zechner, R; Levak-Frank, S; Van Eck, M; Kratky, D
Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice.
Arterioscler Thromb Vasc Biol. 2011; 31(1): 67-73.
Doi: 10.1161/ATVBAHA.110.215814
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** Pfeifer, T; Buchebner, M; Chandak, PG; Patankar, J; Kratzer, A; Obrowsky, S; Rechberger, GN; Kadam, RS; Kompella, UB; Kostner, GM; Kratky, D; Levak-Frank, S
Synthetic LXR agonist suppresses endogenous cholesterol biosynthesis and efficiently lowers plasma cholesterol.
Curr Pharm Biotechnol. 2011; 12(2):285-292
Doi: 10.2174/138920111794295774
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2010
Originalarbeit (Zeitschrift)
** Buchebner, M; Pfeifer, T; Rathke, N; Chandak, PG; Lass, A; Schreiber, R; Kratzer, A; Zimmermann, R; Sattler, W; Koefeler, H; Froehlich, E; Kostner, GM; Birner-Gruenberger, R; Chiang, KP; Haemmerle, G; Zechner, R; Levak-Frank, S; Cravatt, BF; Kratky, D
Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363.
J Lipid Res. 2010; 51(10): 2896-2908.
Doi: 10.1194/jlr.M004259
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** Chandak, PG; Radovic, B; Aflaki, E; Kolb, D; Buchebner, M; Fröhlich, E; Magnes, C; Sinner, F; Haemmerle, G; Zechner, R; Tabas, I; Levak-Frank, S; Kratky, D
Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase.
J Biol Chem. 2010; 285(26):20192-20201
Doi: 10.1074/jbc.M110.107854
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Abstract (Zeitschrift)
** Aflaki, E; Malli, R; Radovic, B; Eisenberg, T; Ring, J; Chandak, PG; Graier, W; Madeo, F; Kratky, D
ADIPOSE TRIGLYCERIDE LIPASE DEFICIENCY RESULTS IN MACROPHAGE APOPTOSIS
ATHEROSCLER SUPPL. 2010; 11(2):211--Gordon Research Conference; August 2010; MA, USA.
Doi: 10.1016/S1567-5688(10)70278-6
[Oral Communication]
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** Chandak, P; Lammers, B; Radovic, B; Aflaki, E; Buchebner, M; Haemmerle, G; Zechner, R; van Eck, M; Kratky, D
ADIPOSE TRIGLYCERIDE LIPASE DEFICIENCY AFFECTS MACROPHAGE MORPHOLOGY AND FUNCTION AND SIGNIFICANTLY REDUCES ATHEROSCLEROSIS IN LDLR-/- MICE
ATHEROSCLER SUPPL. 2010; 11(2):W4-Banff, Alberta.
Doi: 10.1016/S1567-5688(10)70005-2
[Oral Communication]
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2009
Originalarbeit (Zeitschrift)
** Anandharajan, R; Sayyed, SG; Doshi, LS; Dixit, P; Chandak, PG; Dixit, AV; Brahma, MK; Deshmukh, NJ; Gupte, R; Damre, A; Suthar, J; Padigaru, M; Sharma, SD; Nemmani, KV
18F9 (4-(3,6-bis (ethoxycarbonyl)-4,5,6,7-tetrahydrothieno (2,3-c) pyridin-2-ylamino)-4-oxobutanoic acid) enhances insulin-mediated glucose uptake in vitro and exhibits antidiabetic activity in vivo in db/db mice.
Metabolism. 2009; 58(10): 1503-1516.
Doi: 10.1016/j.metabol.2009.04.036
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** Chandak, PG; Gaikwad, AB; Tikoo, K
Gallotannin ameliorates the development of streptozotocin-induced diabetic nephropathy by preventing the activation of PARP.
Phytother Res. 2009; 23(1):72-77
Doi: 10.1002/ptr.2559
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** Doshi, LS; Brahma, MK; Sayyed, SG; Dixit, AV; Chandak, PG; Pamidiboina, V; Motiwala, HF; Sharma, SD; Nemmani, KV
Acute administration of GPR40 receptor agonist potentiates glucose-stimulated insulin secretion in vivo in the rat.
Metabolism. 2009; 58(3): 333-343.
Doi: 10.1016/j.metabol.2008.10.005
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** Kratzer, A; Buchebner, M; Pfeifer, T; Becker, TM; Uray, G; Miyazaki, M; Miyazaki-Anzai, S; Ebner, B; Chandak, PG; Kadam, RS; Calayir, E; Rathke, N; Ahammer, H; Radovic, B; Trauner, M; Hoefler, G; Kompella, UB; Fauler, G; Levi, M; Levak-Frank, S; Kostner, GM; Kratky, D
Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia.
J Lipid Res. 2009; 50(2): 312-326.
Doi: 10.1194/jlr.M800376-JLR200
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