Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Konya Viktoria |

** = Publikationen gelistet in SCI/SSCI/Pubmed

2019

Originalarbeit (Zeitschrift)

** Maric, J; Ravindran, A; Mazzurana, L; Van Acker, A; Rao, A; Kokkinou, E; Ekoff, M; Thomas, D; Fauland, A; Nilsson, G; Wheelock, CE; Dahlén, SE; Ferreirós, N; Geisslinger, G; Friberg, D; Heinemann, A; Konya, V; Mjösberg, J Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation.
J Allergy Clin Immunol. 2019; 143(6):2202-2214 Doi: 10.1016/j.jaci.2018.10.069 [OPEN ACCESS]
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2018

Originalarbeit (Zeitschrift)

** Konya, V; Czarnewski, P; Forkel, M; Rao, A; Kokkinou, E; Villablanca, EJ; Almer, S; Lindforss, U; Friberg, D; Höög, C; Bergman, P; Mjösberg, J Vitamin D downregulates the IL-23 receptor pathway in human mucosal group 3 innate lymphoid cells.
J Allergy Clin Immunol. 2018; 141(1):279-292 Doi: 10.1016/j.jaci.2017.01.045 [OPEN ACCESS]
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** Maric, J; Ravindran, A; Mazzurana, L; Björklund, ÅK; Van Acker, A; Rao, A; Friberg, D; Dahlén, SE; Heinemann, A; Konya, V; Mjösberg, J Prostaglandin E2 suppresses human group 2 innate lymphoid cell function.
J Allergy Clin Immunol. 2018; 141(5):1761-1773 Doi: 10.1016/j.jaci.2017.09.050 [OPEN ACCESS]
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2017

Originalarbeit (Zeitschrift)

** Bärnthaler, T; Maric, J; Platzer, W; Konya, V; Theiler, A; Hasenöhrl, C; Gottschalk, B; Trautmann, S; Schreiber, Y; Graier, WF; Schicho, R; Marsche, G; Olschewski, A; Thomas, D; Schuligoi, R; Heinemann, A The Role of PGE2 in Alveolar Epithelial and Lung Microvascular Endothelial Crosstalk.
Sci Rep. 2017; 7(1):7923-7923 Doi: 10.1038/s41598-017-08228-y [OPEN ACCESS]
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2016

Originalarbeit (Zeitschrift)

** Björklund, ÅK; Forkel, M; Picelli, S; Konya, V; Theorell, J; Friberg, D; Sandberg, R; Mjösberg, J The heterogeneity of human CD127(+) innate lymphoid cells revealed by single-cell RNA sequencing.
Nat Immunol. 2016; 17(4):451-460 Doi: 10.1038/ni.3368
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** Díaz-Pérez, FI; Hiden, U; Gauster, M; Lang, I; Konya, V; Heinemann, A; Lögl, J; Saffery, R; Desoye, G; Cvitic, S Post-transcriptional down regulation of ICAM-1 in feto-placental endothelium in GDM.
Cell Adh Migr. 2016; 10(1-2):18-27 Doi: 10.1080/19336918.2015.1127467 [OPEN ACCESS]
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** Jandl, K; Stacher, E; Bálint, Z; Sturm, EM; Maric, J; Peinhaupt, M; Luschnig, P; Aringer, I; Fauland, A; Konya, V; Dahlen, SE; Wheelock, CE; Kratky, D; Olschewski, A; Marsche, G; Schuligoi, R; Heinemann, A Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung.
J Allergy Clin Immunol. 2016; 137(3):833-843 Doi: 10.1016/j.jaci.2015.11.012 [OPEN ACCESS]
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** Theiler, A; Konya, V; Pasterk, L; Maric, J; Bärnthaler, T; Lanz, I; Platzer, W; Schuligoi, R; Heinemann, A The EP1/EP3 receptor agonist 17-pt-PGE2 acts as an EP4 receptor agonist on endothelial barrier function and in a model of LPS-induced pulmonary inflammation.
Vascul Pharmacol. 2016; 87(4):180-189 Doi: 10.1016/j.vph.2016.09.008 [OPEN ACCESS]
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Übersichtsarbeit

** Konya, V; Mjösberg, J Lipid mediators as regulators of human ILC2 function in allergic diseases.
Immunol Lett. 2016; 179:36-42 Doi: 10.1016/j.imlet.2016.07.006 [OPEN ACCESS]
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Korrektur

** Björklund, ÅK; Forkel, M; Picelli, S; Konya, V; Theorell, J; Friberg, D; Sandberg, R; Mjösberg, J Corrigendum: The heterogeneity of human CD127(+) innate lymphoid cells revealed by single-cell RNA sequencing.
Nat Immunol. 2016; 17(6): 740-740. Doi: 10.1038/ni0616-740a [OPEN ACCESS]
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Abstract (Zeitschrift)

** Barnthaler, T; Maric, J; Konya, V; Lanz, I; Platzer, W; Schuligoi, R; Heinemann, A PGE2 released by alveolar epithelial cells protects the pulmonary endothelial barrier integrity
ALLERGY. 2016; 71: 169-169.-Meeting of the European-Academy-of-Allergy-and-Clinical-Immunology; JUN 11-15, 2016; Vienna, AUSTRIA. [Poster]
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** Maric, J; Heinemann, A; Konya, V; Mjosberg, J PGE(2) suppresses human group 2 innate lymphoid cell function
ALLERGY. 2016; 71: 25-25.-Meeting of the European-Academy-of-Allergy-and-Clinical-Immunology; JUN 11-15, 2016; Vienna, AUSTRIA. [Oral Communication]
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2015

Originalarbeit (Zeitschrift)

** Adage, T; Konya, V; Weber, C; Strutzmann, E; Fuchs, T; Zankl, C; Gerlza, T; Jeremic, D; Heinemann, A; Kungl, AJ Targeting glycosaminoglycans in the lung by an engineered CXCL8 as a novel therapeutic approach to lung inflammation.
Eur J Pharmacol. 2015; 748(10):83-92 Doi: 10.1016/j.ejphar.2014.12.019
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** Gerlza, T; Winkler, S; Atlic, A; Zankl, C; Konya, V; Kitic, N; Strutzmann, E; Knebl, K; Adage, T; Heinemann, A; Weis, R; Kungl, AJ Designing a mutant CCL2-HSA chimera with high glycosaminoglycan-binding affinity and selectivity.
Protein Eng Des Sel. 2015; 28(8):231-240 Doi: 10.1093/protein/gzv025 [OPEN ACCESS]
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** Konya, V; Maric, J; Jandl, K; Luschnig, P; Aringer, I; Lanz, I; Platzer, W; Theiler, A; Bärnthaler, T; Frei, R; Marsche, G; Marsh, LM; Olschewski, A; Lippe, IT; Heinemann, A; Schuligoi, R Activation of EP4 receptors prevents endotoxin-induced neutrophil infiltration into the airways and enhances microvascular barrier function.
Br J Pharmacol. 2015; 172(18):4454-4468 Doi: 10.1111/bph.13229 [OPEN ACCESS]
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Übersichtsarbeit

** Konya, V; Mjösberg, J Innate lymphoid cells in graft-versus-host disease.
Am J Transplant. 2015; 15(11):2795-2801 Doi: 10.1111/ajt.13394 [OPEN ACCESS]
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2014

Originalarbeit (Zeitschrift)

** Bálint, Z; Zabini, D; Konya, V; Nagaraj, C; Végh, AG; Váró, G; Wilhelm, I; Fazakas, C; Krizbai, IA; Heinemann, A; Olschewski, H; Olschewski, A Double-stranded RNA attenuates the barrier function of human pulmonary artery endothelial cells.
PLoS One. 2014; 8(6):e63776-e63776 Doi: 10.1371/journal.pone.0063776 [OPEN ACCESS]
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** Konya, V; Blättermann, S; Jandl, K; Platzer, W; Ottersbach, PA; Marsche, G; Gütschow, M; Kostenis, E; Heinemann, A A biased non-Gαi OXE-R antagonist demonstrates that Gαi protein subunit is not directly involved in neutrophil, eosinophil, and monocyte activation by 5-oxo-ETE.
J Immunol. 2014; 192(10):4774-4782 Doi: 10.4049/jimmunol.1302013 [OPEN ACCESS]
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** Konya, V; Peinhaupt, M; Heinemann, A Adhesion of eosinophils to endothelial cells or substrates under flow conditions.
Methods Mol Biol. 2014; 1178(5):143-156 Doi: 10.1007/978-1-4939-1016-8_13
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2013

Originalarbeit (Zeitschrift)

** Holzer, M; Trieb, M; Konya, V; Wadsack, C; Heinemann, A; Marsche, G Aging affects high-density lipoprotein composition and function.
Biochim Biophys Acta. 2013; 1831(9):1442-1448 Doi: 10.1016/j.bbalip.2013.06.004 [OPEN ACCESS]
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** Konya, V; Marsche, G; Schuligoi, R; Heinemann, A E-type prostanoid receptor 4 (EP4) in disease and therapy.
Pharmacol Ther. 2013; 138(3):485-502 Doi: 10.1016/j.pharmthera.2013.03.006 [OPEN ACCESS]
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** Konya, V; Üllen, A; Kampitsch, N; Theiler, A; Philipose, S; Parzmair, GP; Marsche, G; Peskar, BA; Schuligoi, R; Sattler, W; Heinemann, A Endothelial E-type prostanoid 4 receptors promote barrier function and inhibit neutrophil trafficking.
J Allergy Clin Immunol. 2013; 131(2):532-40.e1-532-40.e2 Doi: 10.1016/j.jaci.2012.05.008
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** Üllen, A; Singewald, E; Konya, V; Fauler, G; Reicher, H; Nusshold, C; Hammer, A; Kratky, D; Heinemann, A; Holzer, P; Malle, E; Sattler, W Myeloperoxidase-derived oxidants induce blood-brain barrier dysfunction in vitro and in vivo.
PLoS One. 2013; 8(5):e64034-e64034 Doi: 10.1371/journal.pone.0064034 [OPEN ACCESS]
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Korrektur

** Aflaki, E; Balenga, NAB; Luschnig-Schratl, P; Wolinski, H; Povoden, S; Chandak, PG; Bogner-Strauss, JG; Eder, S; Konya, V; Kohlwein, SD; Heinemann, A; Kratky, D; Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis (vol 68, pg 3933, 2011).
CELL MOL LIFE SCI. 2013; 70(14): 2621-2621. Doi: 10.1007/s00018-013-1371-8 [OPEN ACCESS]
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2012

Originalarbeit (Zeitschrift)

** Blättermann, S; Peters, L; Ottersbach, PA; Bock, A; Konya, V; Weaver, CD; Gonzalez, A; Schröder, R; Tyagi, R; Luschnig, P; Gäb, J; Hennen, S; Ulven, T; Pardo, L; Mohr, K; Gütschow, M; Heinemann, A; Kostenis, E A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer.
Nat Chem Biol. 2012; 8(7):631-638 Doi: 10.1038/nchembio.962
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** El-Gamal, D; Holzer, M; Gauster, M; Schicho, R; Binder, V; Konya, V; Wadsack, C; Schuligoi, R; Heinemann, A; Marsche, G Cyanate is a novel inducer of endothelial icam-1 expression.
Antioxid Redox Signal. 2012; 16(2): 129-137. Doi: 10.1089/ars.2011.4090 [OPEN ACCESS]
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** Holzer, M; Zangger, K; El-Gamal, D; Binder, V; Curcic, S; Konya, V; Schuligoi, R; Heinemann, A; Marsche, G Myeloperoxidase-derived chlorinating species induce protein carbamylation through decomposition of thiocyanate and urea: novel pathways generating dysfunctional high-density lipoprotein.
Antioxid Redox Signal. 2012; 17(8):1043-1052 Doi: 10.1089/ars.2011.4403 [OPEN ACCESS]
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** Khan, MJ; Alam, MR; Waldeck-Weiermair, M; Karsten, F; Groschner, L; Riederer, M; Hallstroem, S; Rockenfeller, P; Konya, V; Heinemann, A; Madeo, F; Graier, WF; Malli, R Inhibition of autophagy rescues palmitic acid induced necroptosis of endothelial cells.
J Biol Chem. 2012; 287(25):21110-21120 Doi: 10.1074/jbc.M111.319129 [OPEN ACCESS]
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** Lassance, L; Miedl, H; Konya, V; Heinemann, A; Ebner, B; Hackl, H; Desoye, G; Hiden, U Differential response of arterial and venous endothelial cells to extracellular matrix is modulated by oxygen.
Histochem Cell Biol. 2012; 137(5):641-655 Doi: 10.1007/s00418-012-0917-4
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** Philipose, S; Konya, V; Lazarevic, M; Pasterk, LM; Marsche, G; Frank, S; Peskar, BA; Heinemann, A; Schuligoi, R Laropiprant Attenuates EP3 and TP Prostanoid Receptor-Mediated Thrombus Formation.
PLoS One. 2012; 7(8):e40222-e40222 Doi: 10.1371/journal.pone.0040222 [OPEN ACCESS]
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** Schröder, R; Xue, L; Konya, V; Martini, L; Kampitsch, N; Whistler, JL; Ulven, T; Heinemann, A; Pettipher, R; Kostenis, E PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2.
PLoS One. 2012; 7(3):e33329-e33329 Doi: 10.1371/journal.pone.0033329 [OPEN ACCESS]
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2011

Originalarbeit (Zeitschrift)

** Aflaki, E; Balenga, NA; Luschnig-Schratl, P; Wolinski, H; Povoden, S; Chandak, PG; Bogner-Strauss, JG; Eder, S; Konya, V; Kohlwein, SD; Heinemann, A; Kratky, D Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis.
Cell Mol Life Sci. 2011; 68(23): 3933-3947. Doi: 10.1007/s00018-011-0688-4 [OPEN ACCESS]
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** Demyanets, S; Konya, V; Kastl, SP; Kaun, C; Rauscher, S; Niessner, A; Pentz, R; Pfaffenberger, S; Rychli, K; Lemberger, CE; de Martin, R; Heinemann, A; Huk, I; Gröger, M; Maurer, G; Huber, K; Wojta, J Interleukin-33 induces expression of adhesion molecules and inflammatory activation in human endothelial cells and in human atherosclerotic plaques.
Arterioscler Thromb Vasc Biol. 2011; 31(9):2080-2089 Doi: 10.1161/ATVBAHA.111.231431 [OPEN ACCESS]
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** Gruber-Wackernagel, A; Heinemann, A; Konya, V; Byrne, SN; Singh, TP; Hofer, A; Legat, F; Wolf, P Photohardening restores the impaired neutrophil responsiveness to chemoattractants leukotriene B4 and formyl-methionyl-leucyl-phenylalanin in patients with polymorphic light eruption.
Exp Dermatol. 2011; 20(6):473-476 Doi: 10.1111/j.1600-0625.2011.01264.x
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** Konya, V; Philipose, S; Bálint, Z; Olschewski, A; Marsche, G; Sturm, EM; Schicho, R; Peskar, BA; Schuligoi, R; Heinemann, A Interaction of eosinophils with endothelial cells is modulated by prostaglandin EP4 receptors.
Eur J Immunol. 2011; 41(8):2379-2389 Doi: 10.1002/eji.201141460 [OPEN ACCESS]
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** Luschnig-Schratl, P; Sturm, EM; Konya, V; Philipose, S; Marsche, G; Fröhlich, E; Samberger, C; Lang-Loidolt, D; Gattenlöhner, S; Lippe, IT; Peskar, BA; Schuligoi, R; Heinemann, A EP4 receptor stimulation down-regulates human eosinophil function.
Cell Mol Life Sci. 2011; 68(21): 3573-3587. Doi: 10.1007/s00018-011-0642-5 [OPEN ACCESS]
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** Sturm, EM; Schuligoi, R; Konya, V; Sturm, GJ; Heinemann, A Inhibitory effect of prostaglandin I2 on bone marrow kinetics of eosinophils in the guinea pig.
J Leukoc Biol. 2011; 90(2):285-291 Doi: 10.1189/jlb.0211087 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Hiden, U; Lassance, L; Konya, V; Manuela, M; Heinemann, A; Hackl, H; Desoye, G Novel Vascular Effects of IGF2 on the Feto-Placental Endothelium
REPROD SCI. . 2011; 18(3):291A-291A. [Poster]
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** Philipose, S; Offner, M; Konya, V; Heinemann, A; Schuligoi, R PGE2 INHIBITS THROMBOGENESIS VIA THE EP4 RECEPTOR IN A PROTEIN KINASE C MEDIATED PATHWAY
BASIC CLIN PHARMACOL. . 2011; 109: 98-98.-10th Congress of the European Association for Clinical Pharmacology and Therapeutics; JUN 26-29, 2011; Budapest, HUNGARY. [Poster]
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2010

Originalarbeit (Zeitschrift)

** Konya, V; Sturm, EM; Schratl, P; Beubler, E; Marsche, G; Schuligoi, R; Lippe, IT; Peskar, BA; Heinemann, A Endothelium-derived prostaglandin I(2) controls the migration of eosinophils.
J Allergy Clin Immunol. 2010; 125(5): 1105-1113. Doi: 10.1016/j.jaci.2009.12.002
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** Philipose, S; Konya, V; Sreckovic, I; Marsche, G; Lippe, IT; Peskar, BA; Heinemann, A; Schuligoi, R The Prostaglandin E2 Receptor EP4 Is Expressed by Human Platelets and Potently Inhibits Platelet Aggregation and Thrombus Formation.
Arterioscler Thromb Vasc Biol. 2010; 30(12): 2416-2423. Doi: 10.1161/ATVBAHA.110.216374 [OPEN ACCESS]
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** Schuligoi, R; Sturm, E; Luschnig, P; Konya, V; Philipose, S; Sedej, M; Waldhoer, M; Peskar, BA; Heinemann, A CRTH2 and D-type prostanoid receptor antagonists as novel therapeutic agents for inflammatory diseases.
Pharmacology. 2010; 85(6): 372-382. Doi: 10.1159/000313836 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Heinemann, A; Gruber-Wackernagel, A; Konya, V; Byrne, SN; Singh, TP; Legat, FJ; Hofer, A; Wolf, P Photohardening restores the impaired neutrophil responsiveness to chemoattractants in patients with polymorphic light eruption
J INVEST DERMATOL. 2010; 130: S48-S48. [Oral Communication]
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** Hiden, U; Lassance, L; Konya, V; Heinemann, A; Augsten, M; Hackl, H; Desoye, G VASCULAR EFFECTS OF IGF2 ON THE FETO-PLACENTAL ENDOTHELIUM
PLACENTA. 2010; 31(9): A79-A79. [Poster]
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** Sturm, E; Parzmair, GP; Luschnig-Schratl, P; Konya, V; Heinemann, A EP4 PROSTANOID RECEPTOR SIGNALING IN HUMAN EOSINOPHILS
CYTOMETRY PART B-CLIN CYTOM. 2010; 78B(6): 421-422. [Poster]
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2009

Abstract (Zeitschrift)

** Bálint, Z; Zabini, D; Konya, V; Graier, WF; Preissner, KT; Heinemann, A; Olschewski, H; Olschewski, A Alteration of temporal calcium signalling in human pulmonary artery endothelial cells by double-stranded RNA
WIEN KLIN WOCHENSCHR. 2009; 121(17-18):A45-A46.-ÖGP; JUN 11-13, 2009; Salzburg, AUSTRIA. [Oral Communication]
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** Bálint, Z; Zabini, D; Végh, GA; Váró, G; Wilhelm, I; Krizbai, IA; Kónya, V; Heinemann, A; Olschewski, H; Olschewski, A Double-Stranded RNA Causes Leakage in Human Pulmonary Artery Endothelial Cell Monolayer
Circulation2009; 120(18):S1109--American Heart Association's Scientific Sessions 2009; NOV 14-18; Orlando, Florida, USA. [Poster]
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2008

Originalarbeit (Zeitschrift)

** Sturm, EM; Schratl, P; Schuligoi, R; Konya, V; Sturm, GJ; Lippe, IT; Peskar, BA; Heinemann, A Prostaglandin E2 inhibits eosinophil trafficking through E-prostanoid 2 receptors.
J Immunol. 2008; 181(10): 7273-7283. Doi: 10.4049/jimmunol.181.10.7273 [OPEN ACCESS]
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