Medizinische Universität Graz - Research portal
Heinzel Frank |
** = Publications listed in SCI/SSCI/Pubmed
2022
Full paper/article (Journal)
** Koyani, CN; Scheruebel, S; Jin, G; Kolesnik, E; Zorn-Pauly, K; Mächler, H; Hoefler, G; von, Lewinski, D; Heinzel, FR; Pelzmann, B; Malle, E
Hypochlorite-Modified LDL Induces Arrhythmia and Contractile Dysfunction in Cardiomyocytes.
Antioxidants (Basel). 2021; 11(1):
Doi: 10.3390/antiox11010025
[OPEN ACCESS]
Web of Science
PubMed
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** Primessnig, U; Deißler, PM; Wakula, P; Tran, KL; Hohendanner, F; von, Lewinski, D; Blaschke, F; Knosalla, C; Falk, V; Pieske, B; Grubitzsch, H; Heinzel, FR
Effects of BNP and Sacubitrilat/Valsartan on Atrial Functional Reserve and Arrhythmogenesis in Human Myocardium.
FRONT CARDIOVASC MED. 2022; 9: 859014
Doi: 10.3389/fcvm.2022.859014
[OPEN ACCESS]
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** Stuhlinger, M; Burri, H; Vernooy, K; Garcia, R; Lenarczyk, R; Sultan, A; Brunner, M; Sabbag, A; Ozcan, EE; Ramos, JT; Di Stolfo, G; Suleiman, M; Tinhofer, F; Aristizabal, JM; Cakulev, I; Eidelman, G; Yeo, WT; Lau, DH; Mulpuru, SK; Nielsen, JC; Heinzel, F; Prabhu, M; Rinaldi, CA; Sacher, F; Guillen, R; de Pooter, J; Gandjbakhch, E; Sheldon, S; Prenner, G; Mason, PK; Fichtner, S; Nitta, T
EHRA consensus on prevention and management of interference due to medical procedures in patients with cardiac implantable electronic devices
EUROPACE. 2022;
Doi: 10.1093/europace/euac040
[OPEN ACCESS]
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PubMed
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2021
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** Jin, G; Manninger, M; Adelsmayr, G; Schwarzl, M; Alogna, A; Schönleitner, P; Zweiker, D; Blaschke, F; Sherif, M; Radulovic, S; Wakula, P; Schauer, S; Höfler, G; Reiter, U; Reiter, G; Post, H; Scherr, D; Acsai, K; Antoons, G; Pieske, B; Heinzel, FR
Cellular contribution to left and right atrial dysfunction in chronic arterial hypertension in pigs.
ESC Heart Fail. 2021; 8(1):151-161
Doi: 10.1002/ehf2.13087
[OPEN ACCESS]
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** Odening, KE; Gomez, AM; Dobrev, D; Fabritz, L; Heinzel, FR; Mangoni, ME; Molina, CE; Sacconi, L; Smith, G; Stengl, M; Thomas, D; Zaza, A; Remme, CA; Heijman, J
ESC working group on cardiac cellular electrophysiology position paper: relevance, opportunities, and limitations of experimental models for cardiac electrophysiology research
EUROPACE. 2021; 23(11): 1795-1814.
Doi: 10.1093/europace/euab142
[OPEN ACCESS]
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2019
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** Primessnig, U; Bracic, T; Levijoki, J; Otsomaa, L; Pollesello, P; Falcke, M; Pieske, B; Heinzel, FR
Long-term effects of Na+ /Ca2+ exchanger inhibition with ORM-11035 improves cardiac function and remodelling without lowering blood pressure in a model of heart failure with preserved ejection fraction.
Eur J Heart Fail. 2019; 21(12):1543-1552
Doi: 10.1002/ejhf.1619
[OPEN ACCESS]
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2018
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** Manninger, M; Alogna, A; Zweiker, D; Zirngast, B; Reiter, S; Herbst, V; Maechler, H; Pieske, BM; Heinzel, FR; Brussee, H; Post, H; Scherr, D
Mild hypothermia (33°C) increases the inducibility of atrial fibrillation: An in vivo large animal model study.
Pacing Clin Electrophysiol. 2018; 41(7):720-726
Doi: 10.1111/pace.13351
[OPEN ACCESS]
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** Manninger, M; Zweiker, D; van Hunnik, A; Alogna, A; Prassl, AJ; Schipke, J; Zeemering, S; Zirngast, B; Schönleitner, P; Schwarzl, M; Herbst, V; Thon-Gutschi, E; Huber, S; Rohrer, U; Ebner, J; Brussee, H; Pieske, BM; Heinzel, FR; Verheule, S; Antoons, G; Lueger, A; Mühlfeld, C; Plank, G; Schotten, U; Post, H; Scherr, D
Arterial hypertension drives arrhythmia progression via specific structural remodeling in a porcine model of atrial fibrillation.
Heart Rhythm. 2018; 15(9):1328-1336
Doi: 10.1016/j.hrthm.2018.05.016
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** Mhatre, KN; Wakula, P; Klein, O; Bisping, E; Völkl, J; Pieske, B; Heinzel, FR
Crosstalk between FGF23- and angiotensin II-mediated Ca2+ signaling in pathological cardiac hypertrophy.
Cell Mol Life Sci. 2018; 75(23):4403-4416
Doi: 10.1007/s00018-018-2885-x
[OPEN ACCESS]
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Abstract (Journal)
** Heinzel, FR; Mhatre, K; Wakula, P; Klein, O; Bisping, E; Voelkl, J; Pieske, BM
FGF23-and angiotensin II signaling cross-talk in cardiomyocytes
EUR HEART J. 2018; 39: 181-181.
Web of Science
** Mhatre, KN; Wakula, P; Bisping, E; Pieske, B; Heinzel, F
Autocrine angiotensin II-signaling in FGF23-induced Ca2+-mediated hypertrophy in ventricular cardiomyocytes
CARDIOVASC RES. . 2018; 114: S126-S126.-5th Congress of the ESC-Council-on-Basic-Cardiovascular-Science on Frontiers in Cardio Vascular Biology; APR 20-22, 2018; Vienna, AUSTRIA.
Doi: 10.1093/cvr/cvy060.374
[Poster]
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** Mhatre, KN; Wakula, P; Pieske, B; Heinzel, F
The Interplay between FGF23-and Angiotensin II- Mediated Calcium Signaling in Cardiac Hypertrophy
BIOPHYS J. . 2018; 114(3):467A-467A.-62nd Annual Meeting of the Biophysical-Society; FEB 17-21, 2018; San Francisco, CA.
[Poster]
Web of Science
** Mhatre, KNK; Wakula, P; Klein, O; Bisping, E; Volkl, J; Pieske, B; Heinzel, F
FGF23 induces local angiotensin II signaling in cardiomyocytes
EUR J HEART FAIL. . 2018; 20: 620-620.-Heart Failure 2018 and the World Congress on Acute Heart Failure; MAY 26-29, 2018; Vienna, AUSTRIA.
[Poster]
Web of Science
** Primessnig, U; Bracic, T; Pollesello, P; Pieske, B; Heinzel, FR
Inhibition of the Na+/Ca2+exchanger (NCX) improves cardiac remodeling and diastolic function in heart failure with preserved ejection fraction.
EUR J HEART FAIL. . 2018; 20: 339-339.
[Poster]
Web of Science
2017
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** Wakula, P; Neumann, B; Kienemund, J; Thon-Gutschi, E; Stojakovic, T; Manninger, M; Scherr, D; Scharnagl, H; Kapl, M; Pieske, B; Heinzel, FR
CHA2DS2-VASc score and blood biomarkers to identify patients with atrial high-rate episodes and paroxysmal atrial fibrillation.
Europace. 2017; 19(4):544-551
Doi: 10.1093/europace/euw101
[OPEN ACCESS]
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Abstract (Journal)
** Mhatre, K; Wakula, P; Menzel, S; Bisping, E; Pieske, B; Heinzel, F
Crosstalk between FGF23 and angiotensin II-mediated calcium handling in cardiac hypertrophy.
EUR J HEART FAIL. .. 2017; 19: 9-9.
[Poster]
Web of Science
2016
Full paper/article (Journal)
** Primessnig, U; Schönleitner, P; Höll, A; Pfeiffer, S; Bracic, T; Rau, T; Kapl, M; Stojakovic, T; Glasnov, T; Leineweber, K; Wakula, P; Antoons, G; Pieske, B; Heinzel, FR
Novel pathomechanisms of cardiomyocyte dysfunction in a model of heart failure with preserved ejection fraction.
Eur J Heart Fail. 2016; 18(8):987-997
Doi: 10.1002/ejhf.524
[OPEN ACCESS]
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** Voelkl, J; Alesutan, I; Primessnig, U; Feger, M; Mia, S; Jungmann, A; Castor, T; Viereck, R; Stöckigt, F; Borst, O; Gawaz, M; Schrickel, JW; Metzler, B; Katus, HA; Müller, OJ; Pieske, B; Heinzel, FR; Lang, F
AMP-activated protein kinase α1-sensitive activation of AP-1 in cardiomyocytes.
J Mol Cell Cardiol. 2016; 97(4):36-43
Doi: 10.1016/j.yjmcc.2016.04.009
Web of Science
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Abstract (Journal)
** Djalinac, N; Mhatre, K; Kaltenegger, H; Lohberger, B; Thon-Gutschi, EM; Herbst, V; Sedej, S; Heinzel, F; Bisping, E
Differential characteristics of hypertrophy induced by tachycardia, neurohumoral activation or stretch
WIEN KLIN WOCHENSCHR. 2016; 128: S312-S312.
[Poster]
Web of Science
** Manninger, M; Zweiker, D; Herbst, V; Thon-Gutschi, E; Zirngast, B; Huber, S; Ebner, J; Pieske, BM; Brussee, H; Schotten, U; Heinzel, FR; Post, H; Scherr, D
Increased arrhythmia stability is associated with risk-factor specific structural remodelling in a porcine model of arterial hypertension and atrial fibrillation
WIEN KLIN WOCHENSCHR. 2016; 128: S252-S253.
[Poster]
Web of Science
** Manninger, M; Zweiker, D; Van Hunnik, A; Alogna, A; Schoenleitner, P; Schwarzl, M; Herbst, V; Zirngast, B; Huber, S; Pieske, BM; Schotten, U; Antoons, G; Heinzel, FR; Post, H; Scherr, D
Increased arrhythmia stability is associated with risk-factor specific structural remodelling in a porcine model of arterial hypertension and atrial fibrillation
EUR HEART J. 2016; 37: 880-880.-Congress of the European-Society-of-Cardiology (ESC); AUG 27-31, 2016; Rome, ITALY.
[Poster]
Web of Science
** Primessnig, U; Bracic, T; Pollesello, P; Pieske, B; Heinzel, FR
Na+/Ca2+Exchanger (NCX) inhibition with ORM 11035 improves cardiac function and remodeling without lowering blood pressure in a model of heart failure with preserved ejection fraction
EUR J HEART FAIL. .. 2016; 18: 27-27.
[Poster]
Web of Science
** Rohrer, U; Manninger, M; Zweiker, D; Herbst, V; Thon-Gutschi, E; Zirngast, B; Huber, S; Pieske, BM; Brussee, H; Schotten, U; Heinzel, FR; Post, H; Scherr, D
Structural remodelling in a porcine model of rapid atrial pacing and arterial hypertension
WIEN KLIN WOCHENSCHR. 2016; 128: S253-S254.
[Poster]
Web of Science
2015
Full paper/article (Journal)
** Alesutan, I; Voelkl, J; Stöckigt, F; Mia, S; Feger, M; Primessnig, U; Sopjani, M; Munoz, C; Borst, O; Gawaz, M; Pieske, B; Metzler, B; Heinzel, F; Schrickel, JW; Lang, F
AMP-activated protein kinase α1 regulates cardiac gap junction protein connexin 43 and electrical remodeling following pressure overload.
Cell Physiol Biochem. 2015; 35(1):406-418
Doi: 10.1159/000369706
[OPEN ACCESS]
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** Doleschal, B; Primessnig, U; Wölkart, G; Wolf, S; Schernthaner, M; Lichtenegger, M; Glasnov, TN; Kappe, CO; Mayer, B; Antoons, G; Heinzel, F; Poteser, M; Groschner, K
TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1.
Cardiovasc Res. 2015; 106(1):163-173
Doi: 10.1093/cvr/cvv022
[OPEN ACCESS]
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Review
** Lip, GY; Heinzel, FR; Gaita, F; Juanatey, JR; Le Heuzey, JY; Potpara, T; Svendsen, JH; Vos, MA; Anker, SD; Coats, AJ; Haverkamp, W; Manolis, AS; Chung, MK; Sanders, P; Pieske, B
European Heart Rhythm Association/Heart Failure Association joint consensus document on arrhythmias in heart failure, endorsed by the Heart Rhythm Society and the Asia Pacific Heart Rhythm Society.
Eur J Heart Fail. 2015; 17(9):848-874
Doi: 10.1002/ejhf.338
[OPEN ACCESS]
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Correction
** Koyani, CN; Windischhofer, W; Rossmann, C; Heinzel, FR; Sattler, W; Malle, E
Is recurrent pericarditis a risk for constrictive evolution? Reply (vol 177, pg 140, 2014)
INT J CARDIOL. 2015; 189: 108-108.
Doi: 10.1016/j.ijcard.2014.12.040
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Abstract (Journal)
** Primessnig, U; Bracic, T; Glasnov, T; Pieske, B; Heinzel, FR
Chronic inhibition of Na+/Ca2+exchanger (NCX) with SEA0400 improves cardiac function in a model of heart failure with preserved ejection fraction
EUR HEART J. . 2015; 36: 365-366.-Congress of the European-Society-of-Cardiology (ESC); AUG 29-SEP 02, 2015; London, ENGLAND.
[Oral Communication]
Web of Science
** Primessnig, U; Schoenleitner, P; Schmidt, A; Hoell, A; Wakula, P; Engelhardt, S; Antoons, G; Pieske, B; Heinzel, FR
Treatment with ranolazine attenuates cardiac hypertrophy and contractile dysfunction in a murine model of heart failure induced by chronic beta1-adrenergic stimulation
EUR HEART J. . 2015; 36: 666-666.-Congress of the European-Society-of-Cardiology (ESC); AUG 29-SEP 02, 2015; London, ENGLAND.
[Oral Communication]
Web of Science
** Wakula, P; Neumann, B; Kienemund, J; Thon-Gutschi, E; Stojakovic, T; Scharnagl, H; Pieske, B; Kapl, M; Heinzel, FR
Comparison of emerging blood biomarkers, NTproBNP and the CHA2DS2-VASc score in the prediction of paroxysmal atrial fibrillation in patients with continuous rhythm monitoring.
EUR HEART J. 2015; 36: 913-913.-Congress of the European-Society-of-Cardiology (ESC); AUG 29 - SEP 02, 2015; London, UNITED KINGDOM.
[Poster]
Web of Science
2014
Full paper/article (Journal)
** Hammer, KP; Hohendanner, F; Blatter, LA; Pieske, BM; Heinzel, FR
Variations in local calcium signaling in adjacent cardiac myocytes of the intact mouse heart detected with two-dimensional confocal microscopy.
Front Physiol. 2014; 5(4):517-517
Doi: 10.3389/fphys.2014.00517
[OPEN ACCESS]
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** Koyani, CN; Windischhofer, W; Rossmann, C; Jin, G; Kickmaier, S; Heinzel, FR; Groschner, K; Alavian-Ghavanini, A; Sattler, W; Malle, E
15-deoxy-Δ¹²,¹⁴-PGJ₂ promotes inflammation and apoptosis in cardiomyocytes via the DP2/MAPK/TNFα axis.
Int J Cardiol. 2014; 173(3):472-480
Doi: 10.1016/j.ijcard.2014.03.086
[OPEN ACCESS]
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** Sedej, S; Schmidt, A; Denegri, M; Walther, S; Matovina, M; Arnstein, G; Gutschi, EM; Windhager, I; Ljubojević, S; Negri, S; Heinzel, FR; Bisping, E; Vos, MA; Napolitano, C; Priori, SG; Kockskämper, J; Pieske, B
Subclinical abnormalities in sarcoplasmic reticulum Ca(2+) release promote eccentric myocardial remodeling and pump failure death in response to pressure overload.
J Am Coll Cardiol. 2014; 63(15):1569-1579
Doi: 10.1016/j.jacc.2013.11.010
[OPEN ACCESS]
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Review
** Bisping, E; Wakula, P; Poteser, M; Heinzel, FR
Targeting cardiac hypertrophy: toward a causal heart failure therapy.
J Cardiovasc Pharmacol. 2014; 64(4):293-305
Doi: 10.1097/FJC.0000000000000126
[OPEN ACCESS]
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Correspondence
** Koyani, CN; Windischhofer, W; Rossmann, C; Heinzel, FR; Sattler, W; Malle, E
Response to letter by Tsikas et al.
INT J CARDIOL. 2014; 177(1): 140-141.
Doi: 10.1016/j.ijcard.2014.09.111
Web of Science
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Abstract (Journal)
** Alesutan, I; Voelkl, J; Stoeckigt, F; Primessnig, U; Mia, S; Sopjani, M; Feger, M; Munoz, C; Borst, O; Gawaz, M; Metzler, B; Schrickel, J; Heinzel, F; Lang, F
Ampk alpha 1 deficiency ameliorates cardiac dysfunction following pressure overload
ACTA PHYSIOL. . 2014; 210: 92-92.
[Poster]
Web of Science
** Primessnig, U; Hoell, A; Pfeiffer, S; Bracic, T; Rau, T; Wakula, P; Pieske, BM; Heinzel, FR
Diastolic Ca2+leak and the role of the Na+/Ca2+exchanger (NCX) in a model of heart failure with preserved ejection fraction
EUR HEART J. . 2014; 35: 162-162.-Congress of the European-Society-of-Cardiology (ESC); AUG 30-SEP 03, 2014; Barcelona, SPAIN.
[Poster]
Web of Science
** Primessnig, U; Hoell, A; Pfeiffer, S; Rau, T; Wakula, P; Pieske, B; Heinzel, F
Inhibition of the NA(+)/CA(2+) Exchanger (Ncx) Improves Cardiomyocyte Contractile Dysfunction in a Rat Model with Compensated Renal Failure and Heart Failure with Preserved Ejection Fraction
BIOPHYS J. 2014; 106(2): 115A-115A.
Doi: 10.1016/j.bpj.2013.11.697
[Poster]
Web of Science
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** Primessnig, U; Hoell, A; Wakula, P; Pieske, BM; Heinzel, FR
Na+/Ca2+exchanger (NCX) function and diastolic Ca2+leak in a model of heart failure with preserved ejection fraction
CARDIOVASC RES. 2014; 103:
Doi: 10.1093/cvr/cvu098.104
[Poster]
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** Sedej, S; Matovina, M; Schmidt, A; Ljubojevic, S; Heinzel, FR; Negri, S; Napolitano, C; Vos, MA; Priori, SG; Pieske, B
Reduced pressure overload-induced myocardial remodeling in K201-treated mice with the R4496C cardiac ryanodine receptor mutation
CARDIOVASC RES. 2014; 103: -3rd Congress of the ESC-Council-on-Basic-Cardiovascular-Science on Frontiers in Cardio Vascular Biology; JUL 04-06, 2014; Barcelona, SPAIN.
Doi: 10.1093/cvr/cvu091.70
[Poster]
Web of Science
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** Volkl, J; Alesutan, I; Stoeckigt, F; Primessnig, U; Mia, S; Sopjani, M; Feger, M; Munoz, C; Borst, O; Gawaz, M; Metzler, B; Schrickel, J; Heinzel, F; Lang, F
Ampk alpha 1 deficiency counteracts gap junction remodelling following pressure overload
ACTA PHYSIOL. . 2014; 210: 90-90.
[Poster]
Web of Science
2013
Full paper/article (Journal)
** Hohendanner, F; Ljubojević, S; MacQuaide, N; Sacherer, M; Sedej, S; Biesmans, L; Wakula, P; Platzer, D; Sokolow, S; Herchuelz, A; Antoons, G; Sipido, K; Pieske, B; Heinzel, FR
Intracellular dyssynchrony of diastolic cytosolic [Ca²⁺] decay in ventricular cardiomyocytes in cardiac remodeling and human heart failure.
Circ Res. 2013; 113(5):527-38
Doi: 10.1161/CIRCRESAHA.113.300895
[OPEN ACCESS]
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** Perl, S; Stiegler, P; Rotman, B; Prenner, G; Lercher, P; Anelli-Monti, M; Sereinigg, M; Riegelnik, V; Kvas, E; Kos, C; Heinzel, FR; Tscheliessnigg, KH; Pieske, B
Socio-economic effects and cost saving potential of remote patient monitoring (SAVE-HM trial).
Int J Cardiol. 2013; 169(6):402-407
Doi: 10.1016/j.ijcard.2013.10.019
Web of Science
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Abstract (Journal)
** Doleschal, B; Wolf, S; Schernthaner, M; Wolkart, G; Antoons, G; Heinzel, F; Groschner, K;
Remodelling of the Cardiac NCX1-TRPC3 Signaling Complex Promotes Angiotensin Ii-Induced Arrhythmogenesis.
BIOPHYS J. 2013; 104(2):294A-294A.-57th Annual Meeting of the Biophysical-Society; FEB 02-06, 2013; Philadelphia, PA.
Doi: 10.1016/j.bpj.2012.11.1640
[Poster]
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** Perl, S; Zweiker, D; Colantonio, C; Heinzel, F; Ablasser, C; Kos, C; Schmidt, R; Zweiker, R;
Extreme dipping predicts less calcified coronary arteries.
EUR HEART J. 2013; 34: 1052-1052.-Congress of the European-Society-of-Cardiology (ESC); AUG 31-SEP 04, 2013; Amsterdam, NETHERLANDS.
[Poster]
Web of Science
** Primessnig, U; Hoell, A; Pfeiffer, S; Wakula, P; Stipacek, M; Rau, T; Stojakovic, T; Pieske, B; Heinzel, F
Cellular mechanisms of contractile dysfunction in a rat model with compensated renal failure and heart failure with preserved ejection fraction
EUR HEART J. 2013; 34: 451-451.-Congress of the European-Society-of-Cardiology (ESC); AUG 31-SEP 04, 2013; Amsterdam, NETHERLANDS.
[Poster]
Web of Science
** Sacherer, M; Ljubojevic, S; Sedej, S; Stiegler, P; Sereinigg, M; Groschner, K; Antoons, G; Pieske, BM; Heinzel, FR;
TRPC3 Channels in Angiotensin II-Induced Calcium- Dependent Arrhythmias in Mouse and Human Cardiomyocytes.
BIOPHYS J. 2013; 104(2):434A-434A.-57th Annual Meeting of the Biophysical-Society; FEB 02-06, 2013; Philadelphia, PA.
Doi: 10.1016/j.bpj.2012.11.2416
[Oral Communication]
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** Schoenleitner, P; Wakula, P; Engelhardt, S; Pieske, BM; Heinzel, FR; Antoons, G
Increased Late Sodium Current During Early Heart Failure Development Induced by Chronic Sympathetic Activation
CIRCULATION. 2013; 128(22):
[Poster]
Web of Science
2012
Full paper/article (Journal)
** Beretta, M; Wölkart, G; Schernthaner, M; Griesberger, M; Neubauer, R; Schmidt, K; Sacherer, M; Heinzel, FR; Kohlwein, SD; Mayer, B
Vascular bioactivation of nitroglycerin is catalyzed by cytosolic aldehyde dehydrogenase-2.
Circ Res. 2012; 110(3): 385-393.
Doi: 10.1161/CIRCRESAHA.111.245837
[OPEN ACCESS]
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** Diener, HC; Eikelboom, J; Connolly, SJ; Joyner, CD; Hart, RG; Lip, GY; O Donnell, M; Hohnloser, SH; Hankey, GJ; Shestakovska, O; Yusuf, S; AVERROES Steering Committee and Investigators
Apixaban versus aspirin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a predefined subgroup analysis from AVERROES, a randomised trial.
Lancet Neurol. 2012; 11(3): 225-231.
Doi: 10.1016/S1474-4422(12)70017-0
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** Sacherer, M; Sedej, S; Wakuła, P; Wallner, M; Vos, MA; Kockskämper, J; Stiegler, P; Sereinigg, M; von Lewinski, D; Antoons, G; Pieske, BM; Heinzel, FR; CONTICA investigators
JTV519 (K201) reduces sarcoplasmic reticulum Ca²⁺ leak and improves diastolic function in vitro in murine and human non-failing myocardium.
Br J Pharmacol. 2012; 167(3):493-504
Doi: 10.1111/j.1476-5381.2012.01995.x
[OPEN ACCESS]
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2011
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** Biesmans, L; Macquaide, N; Heinzel, FR; Bito, V; Smith, GL; Sipido, KR
Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density.
PLoS One. 2011; 6(10):e25100-e25100
Doi: 10.1371/journal.pone.0025100
[OPEN ACCESS]
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** Connolly, SJ; Eikelboom, J; Joyner, C; Diener, HC; Hart, R; Golitsyn, S; Flaker, G; Avezum, A; Hohnloser, SH; Diaz, R; Talajic, M; Zhu, J; Pais, P; Budaj, A; Parkhomenko, A; Jansky, P; Commerford, P; Tan, RS; Sim, KH; Lewis, BS; Van Mieghem, W; Lip, GY; Kim, JH; Lanas-Zanetti, F; Gonzalez-Hermosillo, A; Dans, AL; Munawar, M; O'Donnell, M; Lawrence, J; Lewis, G; Afzal, R; Yusuf, S; AVERROES Steering Committee and Investigators
Apixaban in patients with atrial fibrillation.
N Engl J Med. 2011; 364(9):806-817
Doi: 10.1056/NEJMoa1007432
[OPEN ACCESS]
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** Heinzel, FR; Macquaide, N; Biesmans, L; Sipido, K
Dyssynchrony of Ca(2+) release from the sarcoplasmic reticulum as subcellular mechanism of cardiac contractile dysfunction.
J Mol Cell Cardiol. 2011; 50(3): 390-400.
Doi: 10.1016/j.yjmcc.2010.11.008
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** Mühlfeld, C; Das, SK; Heinzel, FR; Schmidt, A; Post, H; Schauer, S; Papadakis, T; Kummer, W; Hoefler, G
Cancer induces cardiomyocyte remodeling and hypoinnervation in the left ventricle of the mouse heart.
PLoS One. 2011; 6(5):e20424-e20424
Doi: 10.1371/journal.pone.0020424
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** Yang, LZ; Kockskämper, J; Khan, S; Suarez, J; Walther, S; Doleschal, B; Unterer, G; Khafaga, M; Mächler, H; Heinzel, FR; Dillmann, WH; Pieske, B; Spiess, J
cAMP- and Ca²(+) /calmodulin-dependent protein kinases mediate inotropic, lusitropic and arrhythmogenic effects of urocortin 2 in mouse ventricular myocytes.
Br J Pharmacol. 2011; 162(2):544-556
Doi: 10.1111/j.1476-5381.2010.01067.x
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Abstract (Journal)
** Rossi, P; Kaliska, G; Scaccia, A; Marrero, F; Dissmann, R; Sanfins, V; Veloso, MP; Heinzel, F; Raciti, G; Biffi, M
CHRONOTROPIC INCOMPETENCE IN PACEMAKER PATIENTS: ASSOCIATION WITH CLINICAL CHARACTERISTICS, DEVICE CHOICE AND PROGRAMMING. PRELIMINARY DATA FROM THE OPTI-MIND STUDY POPULATION
J CARDIOVASC ELECTR. 2011; 22: S134-S135.
[Poster]
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2010
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** Sedej, S; Heinzel, FR; Walther, S; Dybkova, N; Wakula, P; Groborz, J; Gronau, P; Maier, LS; Vos, MA; Lai, FA; Napolitano, C; Priori, SG; Kockskämper, J; Pieske, B
Na+-dependent SR Ca2+ overload induces arrhythmogenic events in mouse cardiomyocytes with a human CPVT mutation.
Cardiovasc Res. 2010; 87(1):50-59
Doi: 10.1093/cvr/cvq007
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** Heinzel, FR; Khan, S; Sedej, S; Freidl, P; Hohendanner, F; Wakula, P; Korff, B; Engelhardt, SE; Pieskel, B
Subcellular mechanisms of early impaired calcium homeostasis with chronic beta1-adrenergic stimulation in mice
EUR HEART J. 2010; 31: 895-895.
[Oral Communication]
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** Sacherer, M; Sedej, S; Gronau, P; Vos, MA; Kockskaemper, J; Pieske, B; Heinzel, FR
JTV519 (K201) decreases Ca2+ overload - induced arrhythmogenic Ca2+ release in mouse cardiac myocytes - the role of CaMKII
EUR HEART J. 2010; 31: 1039-1039.
[Poster]
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** Sedej, S; Walther, S; Schmidt, A; Bisping, E; Heinzel, FR; Priori, SG; Kockskaemper, J; Pieske B
Accelerated progression of stress-induced heart failure in mice with a human CPVT mutation
European Heart Journal2010; 31(1):314-314.-ESC Congress 2010; AUG 28-SEP 1, 2010; Stockholm, SWEDEN.
[Oral Communication]
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2009
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** Lenaerts, I; Bito, V; Heinzel, FR; Driesen, RB; Holemans, P; D'hooge, J; Heidbüchel, H; Sipido, KR; Willems, R
Ultrastructural and functional remodeling of the coupling between Ca2+ influx and sarcoplasmic reticulum Ca2+ release in right atrial myocytes from experimental persistent atrial fibrillation.
Circ Res. 2009; 105(9): 876-885.
Doi: 10.1161/CIRCRESAHA.109.206276
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2008
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** Heinzel, FR; Bito, V; Biesmans, L; Wu, M; Detre, E; von Wegner, F; Claus, P; Dymarkowski, S; Maes, F; Bogaert, J; Rademakers, F; D'hooge, J; Sipido, K
Remodeling of T-tubules and reduced synchrony of Ca2+ release in myocytes from chronically ischemic myocardium.
Circ Res. 2008; 102(3): 338-346.
Doi: 10.1161/CIRCRESAHA.107.160085
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** Heinzel, FR; Gres, P; Boengler, K; Duschin, A; Konietzka, I; Rassaf, T; Snedovskaya, J; Meyer, S; Skyschally, A; Kelm, M; Heusch, G; Schulz, R
Inducible nitric oxide synthase expression and cardiomyocyte dysfunction during sustained moderate ischemia in pigs.
Circ Res. 2008; 103(10): 1120-1127.
Doi: 10.1161/CIRCRESAHA.108.186015
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Review
** Bito, V; Heinzel, FR; Biesmans, L; Antoons, G; Sipido, KR
Crosstalk between L-type Ca2+ channels and the sarcoplasmic reticulum: alterations during cardiac remodelling.
Cardiovasc Res. 2008; 77(2): 315-324.
Doi: 10.1093/cvr/cvm063
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2007
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** Claus, P; Weidemann, F; Dommke, C; Bito, V; Heinzel, FR; D'hooge, J; Sipido, KR; Sutherland, GR; Bijnens, B
Mechanisms of postsystolic thickening in ischemic myocardium: mathematical modelling and comparison with experimental ischemic substrates.
Ultrasound Med Biol. 2007; 33(12):1963-1970
Doi: 10.1016/j.ultrasmedbio.2007.06.003
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2006
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** Heinzel, FR; Luo, Y; Dodoni, G; Boengler, K; Petrat, F; Di Lisa, F; de Groot, H; Schulz, R; Heusch, G
Formation of reactive oxygen species at increased contraction frequency in rat cardiomyocytes.
Cardiovasc Res. 2006; 71(2):374-382
Doi: 10.1016/j.cardiores.2006.05.014
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** Yang, LZ; Kockskämper, J; Heinzel, FR; Hauber, M; Walther, S; Spiess, J; Pieske, B
Urocortin II enhances contractility in rabbit ventricular myocytes via CRF(2) receptor-mediated stimulation of protein kinase A.
Cardiovasc Res. 2006; 69(2):402-411
Doi: 10.1016/j.cardiores.2005.10.015
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2005
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** Bito, V; Heinzel, FR; Claus, P; Bijnens, B; Verbeken, E; Van der Velden, J; Stienen, G; Sipido, KR
Alterations in excitation-contraction coupling in chronically ischemic or hibernating myocardium.
Exp Clin Cardiol. 2005; 10(3):142-145
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** Heinzel, FR; Luo, Y; Li, X; Boengler, K; Buechert, A; García-Dorado, D; Di Lisa, F; Schulz, R; Heusch, G
Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice.
Circ Res. 2005; 97(6):583-586
Doi: 10.1161/01.RES.0000181171.65293.65
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2004
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** Bito, V; Heinzel, FR; Weidemann, F; Dommke, C; van der Velden, J; Verbeken, E; Claus, P; Bijnens, B; De Scheerder, I; Stienen, GJ; Sutherland, GR; Sipido, KR
Cellular mechanisms of contractile dysfunction in hibernating myocardium.
Circ Res. 2004; 94(6):794-801
Doi: 10.1161/01.RES.0000124934.84048.DF
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** Li, X; Heinzel, FR; Boengler, K; Schulz, R; Heusch, G
Role of connexin 43 in ischemic preconditioning does not involve intercellular communication through gap junctions.
J Mol Cell Cardiol. 2004; 36(1):161-163
Doi: 10.1016/j.yjmcc.2003.10.019
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** Louch, WE; Bito, V; Heinzel, FR; Macianskiene, R; Vanhaecke, J; Flameng, W; Mubagwa, K; Sipido, KR
Reduced synchrony of Ca2+ release with loss of T-tubules-a comparison to Ca2+ release in human failing cardiomyocytes.
Cardiovasc Res. 2004; 62(1):63-73
Doi: 10.1016/j.cardiores.2003.12.031
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2003
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** Buhre, W; Heinzel, FR; Grund, S; Sonntag, H; Weyland, A
Extrapolation to zero-flow pressure in cerebral arteries to estimate intracranial pressure.
Br J Anaesth. 2003; 90(3):291-295
Doi: 10.1093/bja/aeg073
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** Jansen, J; Gres, P; Umschlag, C; Heinzel, FR; Degenhardt, H; Schluter, KD; Heusch, G; Schulz, R
Parathyroid hormone-related peptide improves contractile function of stunned myocardium in rats and pigs.
Am J Physiol Heart Circ Physiol. 2003; 284(1):H49-H55
Doi: 10.1152/ajpheart.01037.2001
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** Stankovicová, T; Bito, V; Heinzel, F; Mubagwa, K; Sipido, KR
Isolation and morphology of single Purkinje cells from the porcine heart.
Gen Physiol Biophys. 2003; 22(3):329-340
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2002
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** Heinzel, FR; Bito, V; Volders, PG; Antoons, G; Mubagwa, K; Sipido, KR
Spatial and temporal inhomogeneities during Ca2+ release from the sarcoplasmic reticulum in pig ventricular myocytes.
Circ Res. 2002; 91(11):1023-1030
Doi: 10.1161/01.RES.0000045940.67060.DD
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** Zhou, J; Sack, S; Heinzel, F; Hunold, P; Dagres, N; Erbel, R; Ge, J
A new method for internal cardioversion in patients with persistent atrial fibrillation.
Chin Med J (Engl). 2002; 115(2): 299-301.
(- Case Report)
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2001
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** Heinzel, F; Sack, S; Wolfhardt, U; Dagres, N; Herold, U; Erbel, R
Experiences with a new transvenous electrode for left ventricular stimulation
Herz. 2001; 26(1):79-83
Doi: 10.1007/PL00002009
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** Sack, S; Heinzel, F; Dagres, N; Enger, S; Auricchio, A; Stellbrink, C; Neuzner, J; Potty, P; Maarse, A; Tockman, B; Michel, U; Erbel, R
Stimulation of the left ventricle through the coronary sinus with a newly developed 'over the wire' lead system--early experiences with lead handling and positioning.
Europace. 2001; 3(4):317-323
Doi: 10.1053/eupc.2001.0185
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Review
** Sack, S; Heinzel, F; Dagres, N; Wieneke, H; Erbel, R
Cardiac resynchronization therapy in terminal heart failure: current status and prospects
Herz. 2001; 26(1): 84-88.
Doi: 10.1007/PL00002010
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