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Kockskämper Jens |

Publications

** = Publications listed in SCI/SSCI/Pubmed

2014

Abstract (Journal)

** Ljubojevic, S; Radulovic, S; Sedej, S; Kockskaemper, J; Pieske, B; Alterations of Nuclear Ca2+- Dependent Signalling in Heart Failure.
BIOPHYS J. 2014; 106(2):115A-115A.-58th Annual Meeting of the Biophysical-Society; FEB 15-19, 2014; San Francisco, CA. Doi: 10.1016/j.bpj.2013.11.698 [Poster]
Web of Science FullText FullText_MUG

** Walther, S; Edwards, JN; Pluteanu, F; Renz, S; Schmidt, K; Pieske, B; Kockskaemper, J; Blatter, LA; Urocortin 2 Protects Against Pacing-Induced Alternans via Phosphorylation of Phospholamban in Cardiac Myocytes from Normal and Failing Hearts.
BIOPHYS J. . 2014; 106(2):116A-116A.-58th Annual Meeting of the Biophysical-Society; FEB 15-19, 2014; San Francisco, CA. Doi: 10.1016/j.bpj.2013.11.699 [Poster]
Web of Science FullText FullText_MUG

2013

Full paper/article (Journal)

** Kockskamper, A; von Lewinski, D; Zhu, D; Kockskamper, J; Khafaga, M; Schmidt, AG; Post, H; Pieske, B Relevance of stretch-induced phosphorylation of MAPK and p90rsk in human myocardium.
Front Biosci (Elite Ed). 2013; 5(6):883-892 Doi: 10.2741/E667
PubMed FullText FullText_MUG

Abstract (Journal)

** Ljubojevic, S; Radulovic, S; Sedej, S; Kockskaemper, J; Pieske, B; Early alterations of nuclear Ca2+-dependent signalling in cardiac hypertrophy.
EUR HEART J. 2013; 34: 6-6.-Congress of the European-Society-of-Cardiology (ESC); AUG 31-SEP 04, 2013; Amsterdam, NETHERLANDS. [Oral Communication]
Web of Science

2012

Abstract (Journal)

** Ljubojevic, S; Sedej, S; Sacherer, M; Leitinger, G; Kockskaemper, J; Pieske, B; Nuclear remodeling and altered Ca handling of the nucleus - a novel concept of heart failure progression.
EUR HEART J. 2012; 33: 342-342.-Congress of the European-Society-of-Cardiology (ESC); AUG 25-29, 2012; Munchen, GERMANY. [Oral Communication]
Web of Science

2011

Full paper/article (Journal)

** Ljubojević, S; Walther, S; Asgarzoei, M; Sedej, S; Pieske, B; Kockskämper, J In situ calibration of nucleoplasmic versus cytoplasmic Ca²+ concentration in adult cardiomyocytes.
Biophys J. 2011; 100(10):2356-2366 Doi: 10.1016/j.bpj.2011.03.060 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

Abstract (Journal)

** Ljubojevic, S; Sedej, S; Holzer, M; Marsche, G; Marijanski, V; Kockskaemper, J; Pieske, B Subcellular localization and expression levels of TRPC3, ORAI1, and STIM1 in normal and hypertrophied mouse heart
EUR HEART J SUPPL. 2011; 13(A):A37-A37.-10th International Conference of Non-Invasive Cardiovascular Imaging; MAY 15-18, 2011; Amsterdam, NETHERLANDS. [Oral Communication]
Web of Science

** Ljubojevic, S; Sedej, S; Sacherer, M; Kockskaemper, J; Pieske, B Perinuclear Ca Stores Remodeling During Hypertrophy and End-Stage Heart Failure
CIRC RES. . 2011; 109(12):E59-E59.-American-Heart-Association Scientific Sessions on Resuscitation Science Symposium; NOV 12-16, 2011; Orlando, FL. [Poster]
Web of Science

2010

Full paper/article (Journal)

** Sedej, S; Heinzel, FR; Walther, S; Dybkova, N; Wakula, P; Groborz, J; Gronau, P; Maier, LS; Vos, MA; Lai, FA; Napolitano, C; Priori, SG; Kockskämper, J; Pieske, B Na+-dependent SR Ca2+ overload induces arrhythmogenic events in mouse cardiomyocytes with a human CPVT mutation.
Cardiovasc Res. 2010; 87(1):50-59 Doi: 10.1093/cvr/cvq007 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG Google Scholar

** Wakula, P; Bisping, E; Kockskamper, J; Post, H; Brauer, S; Deuter, M; Oehlmann, R; Besenfelder, U; Lai, FA; Brem, G; Pieske, B CMV promoter is inadequate for expression of mutant human RyR2 in transgenic rabbits
J Pharmacol Toxicol Methods. 2010; 63(2):180-185 Doi: 10.1016/j.vascn.2010.09.007
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** Yang, LZ; Tovote, P; Rayner, M; Kockskamper, J; Pieske, B; Spiess, J Corticotropin-releasing factor receptors and urocortins, links between the brain and the heart.
Eur J Pharmacol. 2010; 632(1-3):1-6 Doi: 10.1016/j.ejphar.2010.01.027
Web of Science PubMed FullText FullText_MUG Google Scholar

Abstract (Journal)

** Ljubojevic, S; Walther, S; Burkert, P; Kockskamper, J Quantification of nuclear Ca2+transients in cardiac myocytes
EUR HEART J. 2010; 31: 895-896. [Oral Communication]
Web of Science FullText

** Sacherer, M; Sedej, S; Gronau, P; Vos, MA; Kockskaemper, J; Pieske, B; Heinzel, FR JTV519 (K201) decreases Ca2+ overload - induced arrhythmogenic Ca2+ release in mouse cardiac myocytes - the role of CaMKII
EUR HEART J. 2010; 31: 1039-1039. [Poster]
Web of Science

** Sedej, S; Walther, S; Schmidt, A; Bisping, E; Heinzel, FR; Priori, SG; Kockskaemper, J; Pieske B Accelerated progression of stress-induced heart failure in mice with a human CPVT mutation
European Heart Journal2010; 31(1):314-314.-ESC Congress 2010; AUG 28-SEP 1, 2010; Stockholm, SWEDEN. [Oral Communication]
Web of Science FullText

2009

Full paper/article (Journal)

** Suckau, L; Fechner, H; Chemaly, E; Krohn, S; Hadri, L; Kockskämper, J; Westermann, D; Bisping, E; Ly, H; Wang, X; Kawase, Y; Chen, J; Liang, L; Sipo, I; Vetter, R; Weger, S; Kurreck, J; Erdmann, V; Tschope, C; Pieske, B; Lebeche, D; Schultheiss, HP; Hajjar, RJ; Poller, WC Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy.
Circulation. 2009; 119(9):1241-1252 Doi: 10.1161/CIRCULATIONAHA.108.783852 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG Google Scholar

** von Lewinski, D; Kockskamper, J; Zhu, D; Post, H; Elgner, A; Pieske, B Reduced Stretch-Induced Force Response in Failing Human Myocardium Caused by Impaired Na+-Contraction Coupling
CIRC-HEART FAIL. 2009; 2(1): 47-55. Doi: 10.1161/CIRCHEARTFAILURE.108.794065 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG Google Scholar

Abstract (Journal)

** Walther, S; Renz, S; Yang, LZ; Spiess, J; Pieske, B; Kockskaemper, J UrocortinII Increases eNOS-mediated NO Production in Rabbit Ventricular Myocytes via Both PKA- and Akt-dependent Pathways
CIRCULATION. 2009; 120(18):S1490-S1490. [Poster]
Web of Science

2008

Full paper/article (Journal)

** Kockskämper, J; Khafaga, M; Grimm, M; Elgner, A; Walther, S; Kockskämper, A; von Lewinski, D; Post, H; Grossmann, M; Dörge, H; Gottlieb, PA; Sachs, F; Eschenhagen, T; Schöndube, FA; Pieske, B Angiotensin II and myosin light-chain phosphorylation contribute to the stretch-induced slow force response in human atrial myocardium.
Cardiovasc Res. 2008; 79(4):642-651 Doi: 10.1093/cvr/cvn126 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG Google Scholar

** Kockskamper, J; Seidlmayer, L; Walther, S; Hellenkamp, K; Maier, LS; Pieske, B Endothelin-1 enhances nuclear Ca2+ transients in atrial myocytes through Ins(1,4,5)P3-dependent Ca2+ release from perinuclear Ca2+ stores.
J Cell Sci. 2008; 121(Pt 2):186-195 Doi: 10.1242/jcs.021386 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG Google Scholar

** von Lewinski, D; Kockskämper, J; Rübertus, SU; Zhu, D; Schmitto, JD; Schöndube, FA; Hasenfuss, G; Pieske, B Direct pro-arrhythmogenic effects of angiotensin II can be suppressed by AT1 receptor blockade in human atrial myocardium.
Eur J Heart Fail. 2008; 10(12): 1172-1176. Doi: 10.1016/j.ejheart.2008.09.014 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG Google Scholar

** von Lewinski, D; Zhu, D; Khafaga, M; Kockskamper, J; Maier, LS; Hasenfuss, G; Pieske, B Frequency-dependence of the slow force response.
Front Biosci. 2008; 13(4): 7202-7209. Doi: 10.2741/3222
Web of Science PubMed FullText FullText_MUG Google Scholar

Review

** Kockskämper, J; von Lewinski, D; Khafaga, M; Elgner, A; Grimm, M; Eschenhagen, T; Gottlieb, PA; Sachs, F; Pieske, B The slow force response to stretch in atrial and ventricular myocardium from human heart: functional relevance and subcellular mechanisms.
Prog Biophys Mol Biol. 2008; 97(2-3): 250-267. Doi: 10.1016/j.pbiomolbio.2008.02.026 [OPEN ACCESS]
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** Kockskämper, J; Zima, AV; Roderick, HL; Pieske, B; Blatter, LA; Bootman, MD Emerging roles of inositol 1,4,5-trisphosphate signaling in cardiac myocytes.
J Mol Cell Cardiol. 2008; 45(2):128-147 Doi: 10.1016/j.yjmcc.2008.05.014 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

2007

Full paper/article (Journal)

** Nakipova, OV; Zakharova, NM; Andreeva, LA; Chumaeva, NA; Averin, A; Kosarskii, LS; Anufriev, AI; Lewinski, D; Kockskamper, J; Pieske, B The seasonal peculiarities of force-frequency relationships in active ground squirrel Spermophilus undulatus ventricle.
Cryobiology. 2007; 55(3):173-181 Doi: 10.1016/j.cryobiol.2007.07.001
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** Schillinger, W; Teucher, N; Sossalla, S; Kettlewell, S; Werner, C; Raddatz, D; Elgner, A; Tenderich, G; Pieske, B; Ramadori, G; Schöndube, FA; Kögler, H; Kockskämper, J; Maier, LS; Schwörer, H; Smith, GL; Hasenfuss, G Negative inotropy of the gastric proton pump inhibitor pantoprazole in myocardium from humans and rabbits: evaluation of mechanisms.
Circulation. 2007; 116(1):57-66 Doi: 10.1161/CIRCULATIONAHA.106.666008 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG Google Scholar

** von Lewinski, D; Bisping, E; Elgner, A; Kockskämper, J; Pieske, B Mechanistic insight into the functional and toxic effects of Strophanthidin in the failing human myocardium.
Eur J Heart Fail. 2007; 9(11):1086-1094 Doi: 10.1016/j.ejheart.2007.08.004 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG Google Scholar

Abstract (Journal)

** Post, H; Kockskamper, A; Kogler, H; von Lewinski, D; Pieske, B p38 MAP kinase decreases stretch-induced force development in normal and failing myocardium.
J MOL CELL CARDIOL. 2007; 42: S52-S52.JUN 22-25, 2007; Bologna, ITALY. Doi: 10.1016/j.yjmcc.2007.03.146 [Poster]
Web of Science FullText FullText_MUG

2006

Full paper/article (Journal)

** Yang, LZ; Kockskämper, J; Heinzel, FR; Hauber, M; Walther, S; Spiess, J; Pieske, B Urocortin II enhances contractility in rabbit ventricular myocytes via CRF(2) receptor-mediated stimulation of protein kinase A.
Cardiovasc Res. 2006; 69(2):402-411 Doi: 10.1016/j.cardiores.2005.10.015 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG Google Scholar

** Zima, AV; Kockskämper, J; Blatter, LA Cytosolic energy reserves determine the effect of glycolytic sugar phosphates on sarcoplasmic reticulum Ca2+ release in cat ventricular myocytes.
J Physiol. 2006; 577(Pt 1):281-293 Doi: 10.1113/jphysiol.2006.117242 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

Abstract (Journal)

** Kockskamper, J; Seidlmayer, L; Walther, S; Pieske, B Endothelin-1 potentiates nuclear calcium transients via IP3-dependent calcium release from perinuclear calcium stores.
CIRCULATION. 2006; 114(18):57-57.NOV 12-15, 2006; Chicago, U.S.A.. [Oral Communication]
Web of Science

** Von Lewinski, D; Kockskamper, J; Zhu, D; Lauterbach, A; Elgner, A; Pieske, B Reduced stretch-induced delayed force response and maintained Frank-Starling mechanism in failing human myocardium.
EUR HEART J. 2006; 27: 845-846.-ESC Annual Congress; SEP 2-6, 2006; Barcelona, SPAIN. [Poster]
Web of Science

** Yang, LZ; Kockskamper, J; Suarez, J; Dillman, W; Pieske, B; Spiess, J UrocortinII (UcnII) increases contractility of mouse ventricular myocytes via corticotropin-releasing factor type-2 receptor (CRF2)
ACTA PHARMACOL SIN. 2006; 27: 166-166.China. [Poster]
Web of Science

Comment

** Kockskämper, J; Pieske, B Phosphorylation of the cardiac ryanodine receptor by Ca2+/calmodulin-dependent protein kinase II: the dominating twin of protein kinase A?
Circ Res. 2006; 99(4):333-335 Doi: 10.1161/01.RES.0000239406.66844.7d [OPEN ACCESS]
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2005

Full paper/article (Journal)

** Kockskämper, J; Zima, AV; Blatter, LA Modulation of sarcoplasmic reticulum Ca2+ release by glycolysis in cat atrial myocytes.
J Physiol. 2005; 564(Pt 3):697-714 Doi: 10.1113/jphysiol.2004.078782 [OPEN ACCESS]
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** Luers, C; Fialka, F; Elgner, A; Zhu, D; Kockskämper, J; von Lewinski, D; Pieske, B Stretch-dependent modulation of Na+i, Ca2+i, and pHi in rabbit myocardium--a mechanism for the slow force response.
Cardiovasc Res. 2005; 68(3):454-463 Doi: 10.1016/j.cardiores.2005.07.001 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

2004

Full paper/article (Journal)

** Despa, S; Kockskämper, J; Blatter, LA; Bers, DM Na/K pump-induced Na(i) gradients in rat ventricular myocytes measured with two-photon microscopy.
Biophys J. 2004; 87(2):1360-1368 Doi: 10.1529/biophysj.103.037895 [OPEN ACCESS]
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** Kockskämper, J; Ahmmed, GU; Zima, AV; Sheehan, KA; Glitsch, HG; Blatter, LA Palytoxin disrupts cardiac excitation-contraction coupling through interactions with P-type ion pumps.
Am J Physiol Cell Physiol. 2004; 287(2):C527-C538 Doi: 10.1152/ajpcell.00541.2003 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

Abstract (Journal)

** Kockskamper, J; Sigirci, E; Pieske, B Arrhythmogenic effects of endothelin-1 in atrial trabeculae from patients with sinus rhythm and atrial fibrillation
J MOL CELL CARDIOL. 2004; 36(5): 739-740.
Web of Science

** Kockskamper, J; Sigirci, E; Rubertus, SU; Pieske, B Endothelin-1 elicits arrhythmias in human atrium via modulation of intracellular calcium release
CIRCULATION. 2004; 110(17): 163-163.
Web of Science

** Kockskamper, J; Sirgirci, E; Pieske, B Cellular mechanisms underlying the positive inotropic and the arrhythmogenic effects of endothelin in human atrium
EUR HEART J. 2004; 25: 636-636.
Web of Science

2003

Full paper/article (Journal)

** Zima, AV; Kockskämper, J; Mejia-Alvarez, R; Blatter, LA Pyruvate modulates cardiac sarcoplasmic reticulum Ca2+ release in rats via mitochondria-dependent and -independent mechanisms.
J Physiol. 2003; 550(Pt 3):765-783 Doi: 10.1113/jphysiol.2003.040345 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

Review

** Blatter, LA; Kockskämper, J; Sheehan, KA; Zima, AV; Hüser, J; Lipsius, SL Local calcium gradients during excitation-contraction coupling and alternans in atrial myocytes.
J Physiol. 2003; 546(Pt 1):19-31 Doi: 10.1113/jphysiol.2002.025239 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

2002

Full paper/article (Journal)

** Erlenkamp, S; Glitsch, HG; Kockskämper, J Dual regulation of cardiac Na+-K+ pumps and CFTR Cl- channels by protein kinases A and C.
Pflugers Arch. 2002; 444(1-2):251-262 Doi: 10.1007/s00424-002-0802-4
Web of Science PubMed FullText FullText_MUG

** Kockskämper, J; Blatter, LA Subcellular Ca2+ alternans represents a novel mechanism for the generation of arrhythmogenic Ca2+ waves in cat atrial myocytes.
J Physiol. 2002; 545(Pt 1):65-79 Doi: 10.1113/jphysiol.2002.025502 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

Comment

** Pieske, B; Kockskämper, J Alternans goes subcellular: a disease of the ryanodine receptor?
Circ Res. 2002; 91(7):553-555 Doi: 10.1161/01.RES.0000036862.37203.F4 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

2001

Full paper/article (Journal)

** Kockskämper, J; Sendhoff, K; Erlenkamp, S; Bordusa, F; Cerovsky, V; Glitsch, HG Differences in the protein-kinase-A-dependent regulation of CFTR Cl- channels and Na+-K+ pumps in guinea-pig ventricular myocytes.
Pflugers Arch. 2001; 441(6):807-815 Doi: 10.1007/s004240000485
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** Kockskämper, J; Sheehan, KA; Bare, DJ; Lipsius, SL; Mignery, GA; Blatter, LA Activation and propagation of Ca(2+) release during excitation-contraction coupling in atrial myocytes.
Biophys J. 2001; 81(5):2590-2605 Doi: 10.1016/S0006-3495(01)75903-6 [OPEN ACCESS]
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2000

Full paper/article (Journal)

** Cerovskı, V; Kockskämper, J; Glitsch, HG; Bordusa, F Semisynthesis of Ht31(493--515): involvement of PKA-anchoring proteins in the regulation of the cAMP-dependent chloride current in heart cells.
Chembiochem. 2000; 1(2):126-129 Doi: 10.1002/1439-7633(20000818)1:2<126::AID-CBIC126>3.3.CO;2-S
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** Kockskamper, J; Erlenkamp, S; Glitsch, HG Activation of the cAMP-protein kinase A pathway facilitates Na+ translocation by the Na+-K+ pump in guinea-pig ventricular myocytes.
J Physiol. 2000; 523 Pt 3(6): 561-574. Doi: 10.1111/j.1469-7793.2000.t01-2-00561.x [OPEN ACCESS]
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1999

Full paper/article (Journal)

** Barmashenko, G; Kockskämper, J; Glitsch, HG Depolarization increases the apparent affinity of the Na+-K+ pump to cytoplasmic Na+ in isolated guinea-pig ventricular myocytes.
J Physiol. 1999; 517 ( Pt 3)(6): 691-698. Doi: 10.1111/j.1469-7793.1999.0691s.x [OPEN ACCESS]
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** Hüser, J; Holda, JR; Kockskamper, J; Blatter, LA Focal agonist stimulation results in spatially restricted Ca2+ release and capacitative Ca2+ entry in bovine vascular endothelial cells.
J Physiol. 1999; 514 ( Pt 1)(5): 101-109. Doi: 10.1111/j.1469-7793.1999.101af.x [OPEN ACCESS]
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1998

Full paper/article (Journal)

** Traebert, M; Trebess, I; Erlenkamp, S; Hüser, J; Kockskämper, J; Glitsch, HG; Hartung, C; Welzel, P High affinity regulation of cardiac Cl- and Ca2+ conductances by (13R)-spiroforskolin.
Naunyn Schmiedebergs Arch Pharmacol. 1998; 358(5):538-546 Doi: 10.1007/PL00005290
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1997

Full paper/article (Journal)

** Kockskämper, J; Gisselmann, G; Glitsch, HG Comparison of ouabain-sensitive and -insensitive Na/K pumps in HEK293 cells.
Biochim Biophys Acta. 1997; 1325(2): 197-208. Doi: 10.1016/S0005-2736(96)00259-3
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** Kockskämper, J; Glitsch, HG Sodium pump of cultured guinea pig atrial myocytes.
Ann N Y Acad Sci. 1997; 834(5):354-356 Doi: 10.1111/j.1749-6632.1997.tb52269.x
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