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Rainer Peter |

** = Publications listed in SCI/SSCI/Pubmed

2025

Full paper/article (Journal)

** Byrne, NJ; Koentges, C; Khan, E; Pfeil, K; Sandulescu, R; Bakshi, S; Költgen, C; Vosko, I; Gollmer, J; Rathner, T; Rothf, G; Hoffmann, MM; Odening, KE; Orstmann, H; Potter, LA; Boded, C; Wolf, D; Sourij, H; Ljubojevic-Holzera, S; Wallnera, M; Rainer, PP; Sedej, S; Scherr, D; von Lewinski, D; Wende, AR; Zirlik, A; Bugger, H Sirtuin 4 accelerates heart failure development by enhancing reactive oxygen species-mediated profibrotic transcriptional signaling
J MOL CELL CARD PLUS. 2025; 12: 100299 Doi: 10.1016/j.jmccpl.2025.100299
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** Chen, YC; Dolladille, C; Rao, A; Palaskas, NL; Deswal, A; Lehmann, L; Cautela, J; Courand, PY; Hayek, S; Zhu, H; Cheng, RK; Alexandre, J; Baldassarre, LA; Roubille, F; Laufer-Perl, M; Asnani, A; Ederhy, S; Tamura, Y; Francis, S; Gaughan, EM; Johnson, DB; Flint, DL; Rainer, PP; Bailly, G; Ewer, SM; Aras, MA; Arangalage, D; Cariou, E; Florido, R; Peretto, G; Itzhaki, Ben, Zadok, O; Akhter, N; Narezkina, A; Levenson, JE; Liu, Y; Crusz, SM; Issa, N; Piriou, N; Leong, D; Sandhu, S; Turker, I; Moliner, P; Obeid, M; Heinzerling, L; Chang, WT; Stewart, A; Venkatesh, V; Du, Z; Yadavalli, A; Kim, D; Chandra, A; Zhang, KW; Power, JR; Moslehi, J; Salem, JE; Zaha, VG, , International, ICI, Myocarditis, Registry Immune Checkpoint Inhibitor Myocarditis and Left Ventricular Systolic Dysfunction.
JACC CardioOncol. 2025; 7(3):234-248 Doi: 10.1016/j.jaccao.2025.01.020 [OPEN ACCESS]
PubMed PUBMED Central FullText FullText_MUG

 

** Lorenzer, L; Schrempf, M; Jauk, S; Kalabakov, S; Pierri, G; Suzuki, KMF; César, HV; Kramer, D; Mazzoncini, de, Azevedo-Marques, P; Rainer, P Harmonization of Electronic Medical Records for Federated Learning: Addressing Challenges in International Healthcare Collaborations.
Stud Health Technol Inform. 2025; 324:141-147 Doi: 10.3233/SHTI250175
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** Messner, M; Pölzl, G; Adlbrecht, C; Altenberger, J; Auer, J; Berent, R; Dörler, J; Zaruba, MM; Ebner, C; Fruhwald, F; Hülsmann, M; Mörtl, D; Rainer, PP; Rab, A; Weber, T; Berger, R, , Heart, Failure, Working, Group, of, The, Austrian, Society, for, Cardiology Diagnosis and treatment of iron deficiency in chronic heart failure : Position statement of the heart failure working group of the Austrian Society of Cardiology.
Wien Klin Wochenschr. 2025; 137(Suppl 3):143-156 Doi: 10.1007/s00508-025-02521-x [OPEN ACCESS]
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** Moik, F; Terbuch, A; Sprakel, A; Pichler, G; Barth, DA; Pichler, R; Rainer, P; Silbernagel, G; Mannweiler, S; Jost, PJ; Ahyai, SA; Bauernhofer, T; Hutterer, GC; Pichler, M Arterial thromboembolic events in testicular cancer patients: short- and long-term incidence, risk factors, and impact on mortality.
J Thromb Haemost. 2025; Doi: 10.1016/j.jtha.2025.01.022
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** Paillard, M; Abdellatif, M; Andreadou, I; Bär, C; Bertrand, L; Brundel, BJJM; Chiva-Blanch, G; Davidson, SM; Dawson, D; Di, Lisa, F; Evans, P; Giricz, Z; Hausenloy, DJ; Kleinbongard, P; Lezoualc'h, F; Liehn, E; Maack, C; Maguy, A; Murphy, E; Perrino, C; Pesce, M; Rainer, PP; Streckfuss-Bömeke, K; Thielmann, M; Tian, R; Tocchetti, CG; Van, Der, Velden, J; Van, Linthout, S; Zacchigna, S; Krieg, T Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function.
Eur J Heart Fail. 2025; Doi: 10.1002/ejhf.3674
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Editorial

** Abdellatif, M; Linke, WA; Dawson, DK, , ESC, Working, Group, on, Myocardial, Function The ESC Working Group on Myocardial Function.
Eur Heart J. 2025; Doi: 10.1093/eurheartj/ehae016
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2024

Full paper/article (Journal)

** Ameri, P; Mercurio, V; Pollesello, P; Anker, MS; Backs, J; Bayes-Genis, A; Borlaug, BA; Burkhoff, D; Caravita, S; Chan, SY; de, Man, F; Giannakoulas, G; González, A; Guazzi, M; Hassoun, PM; Hemnes, AR; Maack, C; Madden, B; Melenovsky, V; Müller, OJ; Papp, Z; Pullamsetti, SS; Rainer, PP; Redfield, MM; Rich, S; Schiattarella, GG; Skaara, H; Stellos, K; Tedford, RJ; Thum, T; Vachiery, JL; van, der, Meer, P; Van, Linthout, S; Pruszczyk, P; Seferovic, P; Coats, AJS; Metra, M; Rosano, G; Rosenkranz, S; Tocchetti, CG A roadmap for therapeutic discovery in pulmonary hypertension associated with left heart failure. A scientific statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Pulmonary Circulation & Right Ventricular Function.
Eur J Heart Fail. 2024; Doi: 10.1002/ejhf.3236 [OPEN ACCESS]
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** Guidetti, F; Giraldo, CIS; Shchendrygina, A; Kida, K; Niederseer, D; Basic, C; Rainer, PP; Zaleska-Kociecka, M; Ogola, E; Mohty, D; Lanfranchi, G; Sari, NY; Einarsson, H; Zurek, M; Ruschitzka, F; Savarese, G; Mewton, N Differences in heart failure with preserved ejection fraction management between care providers: an international survey
EUR J HEART FAIL. 2024; Doi: 10.1002/ejhf.3416 [OPEN ACCESS]
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** Kneihsl, M; Gattringer, T; Hofer, E; Rainer, PP; Ranner, G; Fandler-Höfler, S; Haidegger, M; Perl, S; Enzinger, C; Schmidt, R Cerebral white matter hyperintensities indicate severity and progression of coronary artery calcification.
Sci Rep. 2024; 14(1): 4664 Doi: 10.1038/s41598-024-55305-0 [OPEN ACCESS]
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** Perez-Shibayama, C; Gil-Cruz, C; Cadosch, N; Lütge, M; Cheng, HW; De Martin, A; Frischmann, K; Joachimbauer, A; Onder, L; Papadopoulou, I; Papadopoulou, C; Ring, SD; Krebs, P; Vu, VP; Nägele, MP; Rossi, VA; Parianos, D; Zsilavecz, VW; Cooper, LT; Flammer, A; Ruschitzka, F; Rainer, PP; Schmidt, D; Ludewig, B Bone morphogenic protein-4 availability in the cardiac microenvironment controls inflammation and fibrosis in autoimmune myocarditis
NAT CARDIOVASC RES. 2024; Doi: 10.1038/s44161-024-00432-0
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** Racine, JJ; Bachman, JF; Zhang, JG; Misherghi, A; Khadour, R; Kaisar, S; Bedard, O; Jenkins, C; Abbott, A; Forte, E; Rainer, P; Rosenthal, N; Sattler, S; Serreze, DV Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti-PD-1 Immune Checkpoint Inhibitor Cancer Therapy.
J Immunol. 2024; Doi: 10.4049/jimmunol.2300841 [OPEN ACCESS]
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** Sattler, S; Brandl, K; Eller, K; Rainer, PR Is ischemic heart failure also an auto- immune disease?
J KARDIOL. 2024; 31(7-8):
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** Schwegel, N; Zach, D; Peikert, A; Santner, V; Höller, V; Gollmer, J; Späth, J; Riepl, H; Rainer, PP; Wallner, M; Pilz, S; Zirlik, A; von, Lewinski, D; Ablasser, K; Verheyen, N; Kolesnik, E The Prognostic Value of Right Ventricular Function in Patients with Chronic Heart Failure-A Prospective Study.
J Clin Med. 2024; 13(7): 1930 Doi: 10.3390/jcm13071930 [OPEN ACCESS]
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** Shimizu, GY; Schrempf, M; Romão, EA; Jauk, S; Kramer, D; Rainer, PP; Cardeal, da, Costa, JA; de, Azevedo-Marques, JM; Scarpelini, S; Suzuki, KMF; César, HV; de, Azevedo-Marques, PM Machine learning-based risk prediction for major adverse cardiovascular events in a Brazilian hospital: Development, external validation, and interpretability.
PLoS One. 2024; 19(10):e0311719 Doi: 10.1371/journal.pone.0311719 [OPEN ACCESS]
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** Sokolski, M; Trenson, S; Reszka, K; Urban, S; Sokolska, JM; Biering-Sorensen, T; Lassen, MCH; Skaarup, KG; Basic, C; Mandalenakis, Z; Ablasser, K; Rainer, PP; Wallner, M; Rossi, VA; Lilliu, M; Loncar, G; Cakmak, HA; Ruschitzka, F; Flammer, AJ Phenotype clustering of hospitalized high-risk patients with COVID-19-a machine learning approach within the multicentre, multinational PCHF-COVICAV registry
CARDIOL J. 2024; Doi: 10.5603/cj.98927 [OPEN ACCESS]
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** Verheyen, N; Auer, J; Bonaros, N; Buchacher, T; Dalos, D; Grimm, M; Mayr, A; Rab, A; Reinstadler, S; Scherr, D; Toth, GG; Weber, T; Zach, DK; Zaruba, MM; Zimpfer, D; Rainer, PP; Pölzl, G Austrian consensus statement on the diagnosis and management of hypertrophic cardiomyopathy.
Wien Klin Wochenschr. 2024; 136(Suppl 15): 571-597. Doi: 10.1007/s00508-024-02442-1 [OPEN ACCESS]
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** Zach, DK; Schwegel, N; Santner, V; Winkelbauer, L; Hoeller, V; Kolesnik, E; Gollmer, J; Seggewiss, H; Batzner, A; Perl, S; Wallner, M; Reiter, U; Rainer, PP; Zirlik, A; Ablasser, K; Verheyen, N Low-grade systemic inflammation and left ventricular dysfunction in hypertensive compared to non-hypertensive hypertrophic cardiomyopathy.
Int J Cardiol. 2024; 399:131661 Doi: 10.1016/j.ijcard.2023.131661
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Short report/Letter

** Kolland, M; Rainer, PP; Kirsch, AH Use of Cardiac Troponin Assays in Hemodialysis Patients.
Blood Purif. 2024; 1-3 Doi: 10.1159/000542336 [OPEN ACCESS]
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Review

** Ashour, D; Le, Gouge, K; Rainer, PP; Mariotti-Ferrandiz, E; Campos, Ramos, G Exploring T Cell Receptor Repertoires in Myocardial Diseases.
Circ Res. 2024; 134(12):1808-1823 Doi: 10.1161/CIRCRESAHA.124.323661
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** Falcão-Pires, I; Ferreira, AF; Trindade, F; Bertrand, L; Ciccarelli, M; Visco, V; Dawson, D; Hamdani, N; Van, Laake, LW; Lezoualc'h, F; Linke, WA; Lunde, IG; Rainer, PP; Abdellatif, M; Van, der, Velden, J; Cosentino, N; Paldino, A; Pompilio, G; Zacchigna, S; Heymans, S; Thum, T; Tocchetti, CG Mechanisms of myocardial reverse remodelling and its clinical significance: A scientific statement of the ESC Working Group on Myocardial Function.
Eur J Heart Fail. 2024; Doi: 10.1002/ejhf.3264
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Case Report

** Wagner, CS; Schartner, M; Nehoda, H; Rainer, PP; Schnallinger, M Rare case of human epidermal growth factor receptor 2-positive gastric remnant cancer after bariatric surgery-case report
MEMO-MAG EUR MED ONC. 2024; Doi: 10.1007/s12254-024-01007-2
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Correction

** Fenioux, C; Abbar, B; Boussouar, S; Bretagne, M; Power, JR; Moslehi, JJ; Gougis, P; Amelin, D; Dechartres, A; Lehmann, LH; Courand, PY; Cautela, J; Alexandre, J; Procureur, A; Rozes, A; Leonard-Louis, S; Qin, J; Akhter, N; Aghel, N; Amidi, K; Anderson, E; Arangalage, D; Aras, M; Asnani, A; Baldassarre, LA; Barovila, R; Barroso, AS; Bottinor, W; Bouali, A; Cariou, E; Chang, WT; Cheng, RK; Crusz, SM; Deswal, A; Dietrich, PY; Dy, G; Docq, C; Ewer, S; Fernando, S; Flint, DL; Florido, R; Fukushima, S; Galli, E; Gaughan, E; Habib, M; Haydon, A; Heinzerling, L; Ben Zadok, OI; Issa, N; Karlstaedt, A; Kitagawa, K; Layoun, M; Laufer-Perl, M; Lenneman, C; Leong, D; Lesiuk, C; Levenson, J; Lopez-Fernandez, T; Liu, Y; Machado, K; Moliner, P; Morimoto, R; Obeid, M; Narezkina, A; Palaskas, N; Peretto, G; Piriou, N; Plana, JC; Rainer, PP; Robert-Halabi, M; Rocher, F; Rota, E; Roubille, F; Ruf, T; Sandhu, S; Sanjeev, F; Seki, N; Tajiri, K; Tamura, Y; Thuny, F; Tresorier, R; Turker, I; Warner, E; Zaha, V; Zhu, H; Cheynier, R; Muylder, BCD; Redheuil, A; Tubach, F; Cadranel, J; Milon, A; Ederhy, S; Similowski, T; Johnson, DB; Pizzo, I; Catalan, T; Benveniste, O; Hayek, SS; Allenbach, Y; Rosenzwajg, M; Dolladille, C; Salem, JE Thymus alterations and susceptibility to immune checkpoint inhibitor myocarditis (vol 29, pg 3100, 2023)
NAT MED. 2024; Doi: 10.1038/s41591-023-02771-0
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Abstract (Journal)

** Guidetti, FF; Saldarriaga, C; Shchendrygina, A; Kida, K; Niederseer, D; Basic, C; Rainer, P; Zaleska-Kociecka, M; Ogola, E; Zurek, M; Ruschitzka, F; Savarese, G; Mewton, N HFpEF management comparison between HF-cardiologists, non-HF-cardiologists and other specialties: an international survey
EUR J HEART FAIL. 2024; 26: 49-49. [Poster]
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** Zach, DK; Batzner, A; Schwegel, N; Santner, ; Hoeller, ; Ablasser, K; Morbach, C; Stoerk, S; Maack, C; Reiter, U; Rainer, PP; Frantz, S; Zirlik, A; Seggewiss, H; Verheyen, N Residual mitral leaflet length independently indicates left ventricular outflow tract obstruction in hypertrophic cardiomyopathy
EUR HEART J. 2024; 45: ehae666098 Doi: 10.1093/eurheartj/ehae666.098 [Poster]
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Comment

** Verheyen, N; Rainer, PP Editorial comment regarding article: Incremental prognostic utility of congestion markers in cardiac transthyretin amyloidosis.
Clin Res Cardiol. 2024; Doi: 10.1007/s00392-024-02528-w
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Pre-print

** Power, JR; Dolladille, C; Ozbay, B; Procureur, AM; Ederhy, S; Palaskas, NL; Lehmann, LH; Cautela, J; Courand, PY; Hayek, SS; Zhu, H; Zaha, VG; Cheng, RK; Alexandre, J; Roubille, F; Baldassarre, LA; Chen, YC; Baik, AH; Laufer-Perl, M; Tamura, Y; Asnani, A; Francis, S; Gaughan, EM; Rainer, PP; Bailly, G; Flint, D; Arangalage, D; Cariou, E; Florido, R; Narezkina, A; Liu, Y; Sandhu, S; Leong, D; Issa, N; Piriou, N; Heinzerling, L; Peretto, G; Crusz, SM; Akhter, N; Levenson, JE; Turker, I; Eslami, A; Fenioux, C; Moliner, P; Obeid, M; Chan, WT; Ewer, SM; Kassaian, SE; Johnson, DB; Nohria, A; Zadok, OIB; Moslehi, JJ; Salem, JE, , International, ICI-Myocarditis, Registry Predictors and Risk Score for Immune Checkpoint-Inhibitor-Associated Myocarditis Severity.
medRxiv. 2024; Doi: 10.1101/2024.06.02.24308336 [OPEN ACCESS]
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2023

Full paper/article (Journal)

** Ciccarelli, M; Pires, IF; Bauersachs, J; Bertrand, L; Beauloye, C; Dawson, D; Hamdani, N; Hilfiker-Kleiner, D; van, Laake, LW; Lezoualc'h, F; Linke, WA; Lunde, IG; Rainer, PP; Rispoli, A; Visco, V; Carrizzo, A; Ferro, MD; Stolfo, D; van, der, Velden, J; Zacchigna, S; Heymans, S; Thum, T; Tocchetti, CG Acute heart failure: mechanisms and pre-clinical models-a Scientific Statement of the ESC Working Group on Myocardial Function.
Cardiovasc Res. 2023; 119(14):2390-2404 Doi: 10.1093/cvr/cvad088
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** Delgobo, M; Weiß, E; Ashour, D; Richter, L; Popiolkowski, L; Arampatzi, P; Stangl, V; Arias-Loza, P; Mariotti-Ferrandiz, E; Rainer, PP; Saliba, AE; Ludewig, B; Hofmann, U; Frantz, S; Campos, Ramos, G Myocardial Milieu Favors Local Differentiation of Regulatory T Cells.
Circ Res. 2023; 132(5):565-582 Doi: 10.1161/CIRCRESAHA.122.322183
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** Hardy, SA; Liesinger, L; Patrick, R; Poettler, M; Rech, L; Gindlhuber, J; Mabotuwana, NS; Ashour, D; Stangl, V; Bigland, M; Murtha, LA; Starkey, MR; Scherr, D; Hansbro, PM; Hoefler, G; Campos, Ramos, G; Cochain, C; Harvey, RP; Birner-Gruenberger, R; Boyle, AJ; Rainer, PP Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction.
JACC Basic Transl Sci. 2023; 8(12): 1539-1554. Doi: 10.1016/j.jacbts.2023.05.010 [OPEN ACCESS]
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** Hatab, I; Kneihsl, M; Bisping, E; Rainer, PP; Fandler-Höfler, S; Eppinger, S; Haidegger, M; Berger, N; Mangge, H; Schmidt, R; Enzinger, C; Gattringer, T The value of clinical routine blood biomarkers in predicting long-term mortality after stroke.
Eur Stroke J. 2023; 8(2): 532-540. Doi: 10.1177/23969873231162125 [OPEN ACCESS]
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** Murtha, LA; Hardy, SA; Mabotuwana, NS; Bigland, MJ; Bailey, T; Raguram, K; Liu, SF; Ngo, DT; Sverdlov, AL; Tomin, T; Birner-Gruenberger, R; Hume, RD; Iismaa, SE; Humphreys, DT; Patrick, R; Chong, JJH; Lee, RJ; Harvey, RP; Graham, RM; Rainer, PP; Boyle, AJ Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction
SCI REP-UK. 2023; 13(1): 14995 Doi: 10.1038/s41598-023-41894-9 [OPEN ACCESS]
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** Patel, H; Sintou, A; Chowdhury, RA; Rothery, S; Iacob, AO; Prasad, S; Rainer, PP; Martinón-Torres, F; Sancho-Shimizu, V; Shimizu, C; Dummer, K; Tremoulet, AH; Burns, JC; Sattler, S; Levin, M, , DIAMONDS, consortium Evaluation of Autoantibody Binding to Cardiac Tissue in Multisystem Inflammatory Syndrome in Children and COVID-19 Vaccination-Induced Myocarditis.
JAMA Netw Open. 2023; 6(5): e2314291 Doi: 10.1001/jamanetworkopen.2023.14291 [OPEN ACCESS]
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** Polat, Erdeniz, S; Kramer, D; Schrempf, M; Rainer, PP; Felfernig, A; Tran, TNT; Burgstaller, T; Lubos, S Machine Learning Based Risk Prediction for Major Adverse Cardiovascular Events for ELGA-Authorized Clinics1.
Stud Health Technol Inform. 2023; 301: 20-25. Doi: 10.3233/SHTI230006
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** Santner, V; Riepl, HS; Posch, F; Wallner, M; Rainer, PP; Ablasser, K; Kolesnik, E; Hoeller, V; Zach, D; Schwegel, N; Kreuzer, P; Lueger, A; Petutschnigg, J; Pieske, B; Zirlik, A; Edelmann, F; Verheyen, N Non-eligibility for pivotal HFpEF/HFmrEF outcome trials and mortality in a contemporary heart failure cohort.
Eur J Intern Med. 2023; 118:73-81 Doi: 10.1016/j.ejim.2023.07.027
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** Sattler, S; Campos, Ramos, G; Ludewig, B; Rainer, PP Cardioimmunology: the new frontier!
EUR HEART J. 2023; Doi: 10.1093/eurheartj/ehad230
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** Verheyen, N; Rainer, P Rarely cardiomyopathies
J KARDIOL. 2023; 30(5-6): 124-129.
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Short report/Letter

** Kolland, M; Amenitsch, J; Schreiber, N; Ginthör, N; Schuller, M; Riedl, R; Rainer, PP; Schneditz, D; Niedrist, T; Eller, K; Krietemeyer, B; Rosenkranz, AR; Kirsch, AH Changes in cardiac troponins during hemodialysis depend on hemodialysis membrane and modality: a randomized crossover trial
CLIN KIDNEY J. 2023; Doi: 10.1093/ckj/sfad297
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Review

** Abdellatif, M; Rainer, PP; Sedej, S; Kroemer, G Hallmarks of cardiovascular ageing.
Nat Rev Cardiol. 2023; Doi: 10.1038/s41569-023-00881-3
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Abstract (Journal)

** Benedikt, M; Kolesnik, E; Wallner, M; Hofler, G; Stangl, VM; Zirlik, A; Rainer, P Giant cell myocarditis manifesting as severe heart failure with cardiogenic shock
WIEN KLIN WOCHENSCHR. Abstracts. 2023; 135(S2):S342-S343.-ÖKG Jahrestagung; MAY 31-JUN 3, 2023; Salzburg, AUSTRIA. [Oral Communication]
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** Byrne, N; Koentges, C; Khan, E; Pfeil, K; Sandulescu, R; Bakshi, S; Koltgen, C; Vosko, I; Gollmer, J; Hoffmann, M; Wolf, D; Ljubojevic-Holzer, S; Wallner, M; Rainer, P; Sedej, S; Scherr, D; von Lewinski, D; Wende, A; Zirlik, A; Bugger, H Sirtuin 4 accelerates heart failure development by enhancing reactive oxygen species-mediated profibrotic transcriptional signaling
WIEN KLIN WOCHENSCHR. 2023; 135: S398-S398.-Österreichische Kardiologische Gesellschaft (ÖKG); Salzburg, AUSTRIA. [Poster]
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** Gollmer, J; Horstmann, H; Potter, L; Vosko, I; Tomin, T; Pfeil, K; Briner-Gruenberger, R; Von Lewinski, D; Sedej, S; Scherr, D; Wende, AR; Rainer, P; Zirlik, A; Wolf, D; Bugger, H Molecular alterations of human diabetic heart disease revealed using single nucleus RNA sequencing
EUR HEART J. 2023; 44: -Annual Meeting of the European-Society-of-Cardiology (ESC); AUG 25-28, 2023; Amsterdam, NETHERLANDS. [Poster]
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** Hardy, SS; Patrick, R; Liesinger, L; Gindlehuber, J; Pottler, M; Rech, L; Mabotuwana, N; Stagl, V; Ashour, D; Hofler, G; Cochain, C; Harvey, R; Birner-Gruenberger, R; Boyle, A; Rainer, P Extracellular matrix protein 1 as a novel mediator of inflammation-to-fibrosis progression after myocardial infarction
EUR J HEART FAIL. Abstracts. 2023; 25(S1):14-14.-HFA Winter Research Meeting on Translational Heart Failure; MAY 20-23, 2023; Prague, CZECH REPUBLIC. [Oral Communication]
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** Lugitsch, J; Hoeller, V; Schwegel, N; Santner, V; Gollmer, J; Kolesnik, E; Lipp, R; Niedrist, T; Rainer, P; Zirlik, A; Ablasser, K; Verheyen, N; Zach, D Interleukin-6 plasma levels predict mortality and heart failure events in cardiac transthyretin amyloidosis
EUR HEART J. 2023; 44: -Annual Meeting of the European-Society-of-Cardiology (ESC); AUG 25-28, 2023; Amsterdam, NETHERLANDS. [Poster]
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** Lugitsch, J; Holler, V; Schwegel, N; Santner, V; Gollmer, J; Kolesnik, E; Lipp, R; Niedrist, T; Rainer, P; Zirlik, A; Ablasser, K; Verheyen, N; Zach, D Interleukin-6 plasma levels predict mortality and heart failure events in cardiac transthyretin amyloidosis
WIEN KLIN WOCHENSCHR. 2023; 135: S472-S473. [Poster]
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** Mabotuwana, NS; Skerrett-Byrne, DA; Ashour, DE; Butel-Simoes, L; Mcgee, M; Rech, L; Hardy, SA; Meija, R; Lee, RJ; Lim, SY; Hare, JM; Murtha, LA; Dun, MD; Rainer, PP; Boyle, AJ Harnessing novel paracrine factors from the proteomes of cardiac and mesenchymal stem cells to promote repair of the fibrotic heart
EUR J HEART FAIL. 2023; 25: 453-453. [Poster]
Web of Science

 

** Roessler, P; Zsilavecz, V; Wallner, M; Stangl, V; Schmid, J; Rainer, P Does the performance of endomyocardial biopsy prior to cardiac MRI lead to false positive myocarditis diagnoses?
EUR J HEART FAIL. Abstracts. 2023; 25(S2):367-367.-Heart Failure 2023 and the World Congress on Acute Heart Failure; MAY 20-23, 2023; Prague, CZECH REPUBLIC. [Poster]
Web of Science

 

** Zach, D; Schwegel, N; Hoeller, V; Kolesnik, E; Gollmer, J; Reiter, U; Seggewiss, H; Batzner, A; Zirlik, A; Rainer, P; Ablasser, K; Verheyen, N Comparing indices of systemic inflammation and cardiac phenotype between hypertensive and non-hypertensive hypertrophic cardiomyopathy
EUR HEART J. 2023; 44: -Annual Meeting of the European-Society-of-Cardiology (ESC); AUG 25-28, 2023; Amsterdam, NETHERLANDS. [Poster]
Web of Science

 

** Zach, D; Schwegel, N; Holler, V; Kolesnik, E; Gollmer, J; Reiter, U; Seggewiss, H; Batzner, A; Zirlik, A; Rainer, P; Ablasser, K; Verheyen, N Comparing indices of systemic inflammation and cardiac phenotype in hypertensive and non-hypertensive hypertrophic cardiomyopathy
WIEN KLIN WOCHENSCHR. 2023; 135: S475-S476. [Poster]
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2022

Full paper/article (Journal)

** Abdellatif, M; Trummer-Herbst, V; Heberle, AM; Humnig, A; Pendl, T; Durand, S; Cerrato, G; Hofer, SJ; Islam, M; Voglhuber, J; Ramos, Pittol, JM; Kepp, O; Hoefler, G; Schmidt, A; Rainer, PP; Scherr, D; von, Lewinski, D; Bisping, E; McMullen, JR; Diwan, A; Eisenberg, T; Madeo, F; Thedieck, K; Kroemer, G; Sedej, S Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity.
Circulation. 2022; 145(25):1853-1866 Doi: 10.1161/CIRCULATIONAHA.122.059863 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Bergler-Klein, J; Rainer, PP; Wallner, M; Zaruba, MM; Dörler, J; Böhmer, A; Buchacher, T; Frey, M; Adlbrecht, C; Bartsch, R; Gyöngyösi, M; Fürst, UM Cardio-oncology in Austria: cardiotoxicity and surveillance of anti-cancer therapies : Position paper of the Heart Failure Working Group of the Austrian Society of Cardiology.
Wien Klin Wochenschr. 2022; 134(17-18):654-674 Doi: 10.1007/s00508-022-02031-0 [OPEN ACCESS]
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** Djalinac, N; Kolesnik, E; Maechler, H; Scheruebel-Posch, S; Pelzmann, B; Rainer, PP; Foessl, I; Wallner, M; Scherr, D; Heinemann, A; Sedej, S; Ljubojevic-Holzer, S; von, Lewinski, D; Bisping, E miR-1183 Is a Key Marker of Remodeling upon Stretch and Tachycardia in Human Myocardium.
Int J Mol Sci. 2022; 23(13): Doi: 10.3390/ijms23136962 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Eaton, DM; Martin, TG; Kasa, M; Djalinac, N; Ljubojevic-Holzer, S; Von, Lewinski, D; Pöttler, M; Kampaengsri, T; Krumphuber, A; Scharer, K; Maechler, H; Zirlik, A; McKinsey, TA; Kirk, JA; Houser, SR; Rainer, PP; Wallner, M HDAC Inhibition Regulates Cardiac Function by Increasing Myofilament Calcium Sensitivity and Decreasing Diastolic Tension.
Pharmaceutics. 2022; 14(7): Doi: 10.3390/pharmaceutics14071509 [OPEN ACCESS]
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** Herrero-Galán, E; Martínez-Martín, I; Sánchez-González, C; Vicente, N; Bonzón-Kulichenko, E; Calvo, E; Suay-Corredera, C; Pricolo, MR; Fernández-Trasancos, Á; Velázquez-Carreras, D; Careaga, CB; Abdellatif, M; Sedej, S; Rainer, PP; Giganti, D; Pérez-Jiménez, R; Vázquez, J; Alegre-Cebollada, J Basal oxidation of conserved cysteines modulates cardiac titin stiffness and dynamics.
Redox Biol. 2022; 52:102306 Doi: 10.1016/j.redox.2022.102306 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Ljubojević-Holzer, S; Kraler, S; Djalinac, N; Abdellatif, M; Voglhuber, J; Schipke, J; Schmidt, M; Kling, KM; Franke, GT; Herbst, V; Zirlik, A; von, Lewinski, D; Scherr, D; Rainer, PP; Kohlhaas, M; Nickel, A; Mühlfeld, C; Maack, C; Sedej, S Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling.
Cardiovasc Res. 2022; 118(6):1492-1505 Doi: 10.1093/cvr/cvab112 [OPEN ACCESS]
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** Lyon, AR; López-Fernández, T; Couch, LS; Asteggiano, R; Aznar, MC; Bergler-Klein, J; Boriani, G; Cardinale, D; Cordoba, R; Cosyns, B; Cutter, DJ; de, Azambuja, E; de, Boer, RA; Dent, SF; Farmakis, D; Gevaert, SA; Gorog, DA; Herrmann, J; Lenihan, D; Moslehi, J; Moura, B; Salinger, SS; Stephens, R; Suter, TM; Szmit, S; Tamargo, J; Thavendiranathan, P; Tocchetti, CG; van der Meer, P; van der Pal, HJH; ESC Scientific Document Group 2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS).
Eur Heart J. 2022; 43(41): 4229-4361. Doi: 10.1093/eurheartj/ehac244
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** Lyon, AR; López-Fernández, T; Couch, LS; Asteggiano, R; Aznar, MC; Bergler-Klein, J; Boriani, G; Cardinale, D; Cordoba, R; Cosyns, B; Cutter, DJ; de, Azambuja, E; de Boer, RA; Dent, SF; Farmakis, D; Gevaert, SA; Gorog, DA; Herrmann, J; Lenihan, D; Moslehi, J; Moura, B; Salinger, SS; Stephens, R; Suter, TM; Szmit, S; Tamargo, J; Thavendiranathan, P; Tocchetti, CG; van der Meer, P; van der Pal, HJH; ESC Scientific Document Group 2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS).
Eur Heart J Cardiovasc Imaging. 2022; 23(10): e333-e465. Doi: 10.1093/ehjci/jeac106
PubMed FullText FullText_MUG

 

** Mabotuwana, NS; Rech, L; Lim, J; Hardy, SA; Murtha, LA; Rainer, PP; Boyle, AJ Paracrine Factors Released by Stem Cells of Mesenchymal Origin and their Effects in Cardiovascular Disease: A Systematic Review of Pre-clinical Studies.
Stem Cell Rev Rep. 2022; 18(8):2606-2628 Doi: 10.1007/s12015-022-10429-6 [OPEN ACCESS]
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** Matzer, I; Voglhuber, J; Kiessling, M; Djalinac, N; Trummer-Herbst, V; Mabotuwana, N; Rech, L; Holzer, M; Sossalla, S; Rainer, PP; Zirlik, A; Ljubojevic-Holzer, S β-Adrenergic Receptor Stimulation Maintains NCX-CaMKII Axis and Prevents Overactivation of IL6R-Signaling in Cardiomyocytes upon Increased Workload.
Biomedicines. 2022; 10(7): Doi: 10.3390/biomedicines10071648 [OPEN ACCESS]
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** Papadaki, M; Kampaengsri, T; Barrick, SK; Campbell, SG; von, Lewinski, D; Rainer, PP; Harris, SP; Greenberg, MJ; Kirk, JA Myofilament glycation in diabetes reduces contractility by inhibiting tropomyosin movement, is rescued by cMyBPC domains.
J Mol Cell Cardiol. 2022; 162:1-9 Doi: 10.1016/j.yjmcc.2021.08.012 [OPEN ACCESS]
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** Posch, F; Niedrist, T; Glantschnig, T; Firla, S; Moik, F; Kolesnik, E; Wallner, M; Verheyen, N; Jost, PJ; Zirlik, A; Pichler, M; Balic, M; Rainer, PP Left ventricular ejection fraction and cardiac biomarkers for dynamic prediction of cardiotoxicity in early breast cancer.
Front Cardiovasc Med. 2022; 9: 933428 Doi: 10.3389/fcvm.2022.933428 [OPEN ACCESS]
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** Rech, L; Abdellatif, M; Pöttler, M; Stangl, V; Mabotuwana, N; Hardy, S; Rainer, PP Small molecule STING inhibition improves myocardial infarction remodeling.
Life Sci. 2022; 291:120263 Doi: 10.1016/j.lfs.2021.120263
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** Schrempf, M; Polat, Erdeniz, S; Kramer, D; Jauk, S; Veeranki, SPK; Ribitsch, W; Leodolter, W; Rainer, PP Development of an Architecture to Implement Machine Learning Based Risk Prediction in Clinical Routine: A Service-Oriented Approach.
Stud Health Technol Inform. 2022; 293: 262-269. Doi: 10.3233/SHTI220379
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** Sokolski, M; Trenson, S; Sokolska, JM; D'Amario, D; Meyer, P; Poku, NK; Biering-Sørensen, T; Højbjerg, Lassen, MC; Skaarup, KG; Barge-Caballero, E; Pouleur, AC; Stolfo, D; Sinagra, G; Ablasser, K; Muster, V; Rainer, PP; Wallner, M; Chiodini, A; Heiniger, PS; Mikulicic, F; Schwaiger, J; Winnik, S; Cakmak, HA; Gaudenzi, M; Mapelli, M; Mattavelli, I; Paul, M; Cabac-Pogorevici, I; Bouleti, C; Lilliu, M; Minoia, C; Dauw, J; Costa, J; Celik, A; Mewton, N; Montenegro, CEL; Matsue, Y; Loncar, G; Marchel, M; Bechlioulis, A; Michalis, L; Dörr, M; Prihadi, E; Schoenrath, F; Messroghli, DR; Mullens, W; Lund, LH; Rosano, GMC; Ponikowski, P; Ruschitzka, F; Flammer, AJ Heart failure in COVID-19: the multicentre, multinational PCHF-COVICAV registry.
ESC Heart Fail. 2021; 8(6):4955-4967 Doi: 10.1002/ehf2.13549 [OPEN ACCESS]
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** Tarkhnishvili, A; Koentges, C; Pfeil, K; Gollmer, J; Byrne, NJ; Vosko, I; Lueg, J; Vogelbacher, L; Birkle, S; Tang, S; Bon-Nawul, Mwinyella, T; Hoffmann, MM; Odening, KE; Michel, NA; Wolf, D; Stachon, P; Hilgendorf, I; Wallner, M; Ljubojevic-Holzer, S; von, Lewinski, D; Rainer, P; Sedej, S; Sourij, H; Bode, C; Zirlik, A; Bugger, H Effects of Short Term Adiponectin Receptor Agonism on Cardiac Function and Energetics in Diabetic db/db Mice.
J Lipid Atheroscler. 2022; 11(2):161-177 Doi: 10.12997/jla.2022.11.2.161 [OPEN ACCESS]
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** von, Lewinski, D; Herold, L; Stoffel, C; Pätzold, S; Fruhwald, F; Altmanninger-Sock, S; Kolesnik, E; Wallner, M; Rainer, P; Bugger, H; Verheyen, N; Rohrer, U; Manninger-Wünscher, M; Scherr, D; Renz, D; Yates, A; Zirlik, A; Toth, GG PRospective REgistry of PAtients in REfractory cardiogenic shock-The PREPARE CardShock registry.
Catheter Cardiovasc Interv. 2022; 100(3):319-327 Doi: 10.1002/ccd.30327 [OPEN ACCESS]
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** Wakabayashi, I; Sotoda, Y; Groschner, K; Rainer, PP; Sourij, H Differences in circulating obesity-related microRNAs in Austrian and Japanese men: A two-country cohort analysis.
Metabol Open. 2022; 15: 100206 Doi: 10.1016/j.metop.2022.100206 [OPEN ACCESS]
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Case Report

** Kolesnik, E; Stangl, V; Haring, B; Scherr, D; Rainer, PP Cardiac relapse of extranodal NK/T-cell lymphoma manifesting as incessant ventricular tachycardia: a case report.
Eur Heart J Case Rep. 2022; 6(9): ytac363 Doi: 10.1093/ehjcr/ytac363 (- Case Report) [OPEN ACCESS]
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** Nebert, C; Mayer, C; Zirngast, B; Moser, L; Rainer, P; D'Orazio, M; Hermann, J; Stangl, V; Machler, H Case report: the rare clinical picture of vasculitis of the pericardium in rheumatoid arthritis
EUR SURG. 2022; Doi: 10.1007/s10353-022-00755-x
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Abstract (Journal)

** Eaton, D; Martin, T; Kasa, M; Djalinac, N; Johnson, J; Kolesnik, E; Ljubojevic-Holzer, S; von Lewinski, D; Poettler, M; Kampaengsri, T; Maechler, H; Zirlik, A; McKinsey, T; Kirk, J; Houser, S; Rainer, P; Wallner, M HDAC inhibition modulates cardiomyocyte contractility and myofilament acetylation
J MOL CELL CARDIOL. 2022; 173: S14-S15. Doi: 10.1016/j.yjmcc.2022.08.031 [Poster]
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** Gollmer, J; Potter, L; Vosko, I; Tomin, T; Birner-Gruenberger, R; Von Lewinski, D; Sedej, S; Scherr, D; Wende, AR; Rainer, P; Zirlik, A; Bugger, H Transcriptomic and proteomic profiling of human diabetic heart disease
EUR HEART J. 2022; 43: 2951-2951.
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** Krumphuber, A; Scharer, K; Eaton, D; Ljubojevic-Holzer, S; von Lewinski, D; Maechler, H; Zirlik, A; Houser, S; Rainer, P; Wallner, M Functional effects of class I-selective HDAC-inhibition on human atrial myocardium
J MOL CELL CARDIOL. 2022; 173: S100-S101. Doi: 10.1016/j.yjmcc.2022.08.201 [Poster]
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** Santner, V; Riepl, H; Posch, F; Wallner, M; Rainer, P; Ablasser, K; Kolesnik, E; von Lewinski, D; Kreuzer, P; Lueger, A; Petutschnigg, J; Pieske, B; Zirlik, A; Edelmann, F; Verheyen, N Eligibility for HFpEF/HFmrEF outcome trials and mortality risk in a cohort of decompensated heart failure patients
WIEN KLIN WOCHENSCHR. Abstracts der Österreichische Kardiologische Gesellschaft Jahrestagung 2022. 2022; 134(SUPPL 2):100-100.-Österreichische Kardiologische Gesellschaft Jahrestagung 2022; MAI 25-28, 2022; Salzburg, AUSTRIA. [Poster]
Web of Science

 

** Santner, V; Riepl, H; Wallner, M; Rainer, P; Ablasser, K; Kolesnik, E; Von Lewinski, D; Kreuzer, P; Petutschnigg, J; Pieske, B; Zirlik, A; Edelmann, F; Verheyen, N Eligibility for HFpEF and HFmrEF outcome trials and mortality risk in a cohort of decompensated heart failure patients. Do trial cohorts match with reality?
EUR J HEART FAIL. 2022; 24: 36-37. [Oral Communication]
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** Scharer, K; Krumphuber, A; Eaton, DM; Ljubojevic-Holzer, S; von Lewinski, D; Machler, H; Zirlik, A; Houser, SR; Rainer, P; Wallner, M The effects of selective HDAC-inhibition on myofibril kinetic parameters in human atrial myocardium
WIEN KLIN WOCHENSCHR. 2022; 134(SUPPL 3):223-224. [Oral Communication]
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** Scharer, K; Krumphuber, A; Eaton, DM; Ljubojevic-Holzer, S; von Lewinski, D; Machler, H; Zirlik, A; Houser, SR; Rainer, P; Wallner, M Functional Effects of selective HDAC Inhibition on human atrial Myocardium
WIEN KLIN WOCHENSCHR. Abstracts der Österreichische Kardiologische Gesellschaft Jahrestagung 2022. 2022; 134(SUPPL 2):125-126.-Österreichische Kardiologische Gesellschaft Jahrestagung 2022; MAI 25-28, 2022; Salzburg, AUSTRIA. [Poster]
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2021

Full paper/article (Journal)

** Abdellatif, M; Trummer-Herbst, V; Koser, F; Durand, S; Adão, R; Vasques-Nóvoa, F; Freundt, JK; Voglhuber, J; Pricolo, MR; Kasa, M; Türk, C; Aprahamian, F; Herrero-Galán, E; Hofer, SJ; Pendl, T; Rech, L; Kargl, J; Anto-Michel, N; Ljubojevic-Holzer, S; Schipke, J; Brandenberger, C; Auer, M; Schreiber, R; Koyani, CN; Heinemann, A; Zirlik, A; Schmidt, A; von Lewinski, D; Scherr, D; Rainer, PP; von Maltzahn, J; Mühlfeld, C; Krüger, M; Frank, S; Madeo, F; Eisenberg, T; Prokesch, A; Leite-Moreira, AF; Lourenço, AP; Alegre-Cebollada, J; Kiechl, S; Linke, WA; Kroemer, G; Sedej, S Nicotinamide for the treatment of heart failure with preserved ejection fraction.
Sci Transl Med. 2021; 13(580): eabd7064 Doi: 10.1126/scitranslmed.abd7064 [OPEN ACCESS]
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** Barennes, P; Quiniou, V; Shugay, M; Egorov, ES; Davydov, AN; Chudakov, DM; Uddin, I; Ismail, M; Oakes, T; Chain, B; Eugster, A; Kashofer, K; Rainer, PP; Darko, S; Ransier, A; Douek, DC; Klatzmann, D; Mariotti-Ferrandiz, E Benchmarking of T cell receptor repertoire profiling methods reveals large systematic biases.
Nat Biotechnol. 2021; 39(2):236-245 Doi: 10.1038/s41587-020-0656-3
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** Höller, V; Seebacher, H; Zach, D; Schwegel, N; Ablasser, K; Kolesnik, E; Gollmer, J; Waltl, G; Rainer, PP; Verheyen, S; Zirlik, A; Verheyen, N Myocardial Deformation Analysis in MYBPC3 and MYH7 Related Sarcomeric Hypertrophic Cardiomyopathy-The Graz Hypertrophic Cardiomyopathy Registry.
Genes (Basel). 2021; 12(10): Doi: 10.3390/genes12101469 [OPEN ACCESS]
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** Schmid, J; Kamml, C; Zweiker, D; Hatz, D; Schmidt, A; Reiter, U; Toth, GG; Fuchsjäger, M; Zirlik, A; Binder, JS; Rainer, PP Cardiac Magnetic Resonance Imaging Right Ventricular Longitudinal Strain Predicts Mortality in Patients Undergoing TAVI.
Front Cardiovasc Med. 2021; 8:644500 Doi: 10.3389/fcvm.2021.644500 [OPEN ACCESS]
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** Schrempf, M; Kramer, D; Jauk, S; Veeranki, SPK; Leodolter, W; Rainer, PP Machine Learning Based Risk Prediction for Major Adverse Cardiovascular Events.
Stud Health Technol Inform. 2021; 279: 136-143. Doi: 10.3233/SHTI210100 [OPEN ACCESS]
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** Spray, L; Park, C; Cormack, S; Mohammed, A; Panahi, P; Boag, S; Bennaceur, K; Sopova, K; Richardson, G; Stangl, VM; Rech, L; Rainer, PP; Ramos, GC; Hofmann, U; Stellos, K; Spyridopoulos, I The Fractalkine Receptor CX3CR1 Links Lymphocyte Kinetics in CMV-Seropositive Patients and Acute Myocardial Infarction With Adverse Left Ventricular Remodeling.
Front Immunol. 2021; 12: 605857-605857. Doi: 10.3389/fimmu.2021.605857 [OPEN ACCESS]
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** Tomin, T; Schittmayer, M; Sedej, S; Bugger, H; Gollmer, J; Honeder, S; Darnhofer, B; Liesinger, L; Zuckermann, A; Rainer, PP; Birner-Gruenberger, R Mass Spectrometry-Based Redox and Protein Profiling of Failing Human Hearts.
Int J Mol Sci. 2021; 22(4): Doi: 10.3390/ijms22041787 [OPEN ACCESS]
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** Wakabayashi, I; Sourij, H; Sotoda, Y; Daimon, T; Groschner, K; Rainer, PP Ethnic Differences in Serum Levels of microRNAs Potentially Regulating Alcohol Dehydrogenase 1B and Aldehyde Dehydrogenase 2.
J CLIN MED. 2021; 10(16): Doi: 10.3390/jcm10163678 [OPEN ACCESS]
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Review

** Rech, L; Rainer, PP The Innate Immune cGAS-STING-Pathway in Cardiovascular Diseases - A Mini Review.
Front Cardiovasc Med. 2021; 8: 715903 Doi: 10.3389/fcvm.2021.715903 [OPEN ACCESS]
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Case Report

** Zach, D; Ablasser, K; Kolesnik, E; Hoeller, V; Fruhwald, F; Prüller, F; Reiter, C; Beham-Schmid, C; Lipp, R; Rainer, PP; Zirlik, A; Wölfler, A; Verheyen, N Advanced isolated light chain amyloid cardiomyopathy with negative immunofixation and normal free light chain ratio.
ESC Heart Fail. 2021; 8(4):3397-3402 Doi: 10.1002/ehf2.13381 (- Case Report) [OPEN ACCESS]
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Abstract (Journal)

** Abdellatif, M; Trummer-Herbst, V; Koser, F; Durand, S; Adao, R; Von Lewinski, D; Rainer, P; Scherr, D; Zirlik, A; Leite-Moreira, A; Alegre-Cebollada, J; Kiechl, S; Linke, W; Kroemer, G; Sedej, S Boosting NAD+ metabolism improves diastolic dysfunction in animal models of aging, obesity and hypertension
WIEN KLIN WOCHENSCHR. 2021; 133(SUPPL 3):S53-S54. [Oral Communication]
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** Abdellatif, M; Trummer-Herbst, V; Pendl, T; Hofer, S; Durand, S; Voglhuber, J; Von Lewinski, D; Rainer, P; Scherr, D; Zirlik, A; Eisenberg, T; Kroemer, G; Madeo, F; Bisping, E; Sedej, S Targeting IGF1 Signalling to Promote Cardiac Health and Longevity
WIEN KLIN WOCHENSCHR. 2021; 133(SUPPL 3):S35-S35. [Oral Communication]
Web of Science

 

** Eaton, D; Martin, TG; Kasa, M; Djalinac, N; Johnson, JP; Kolesnik, E; Ljubojevic-Holzer, S; Von Lewinski, D; Maechler, H; Zirlik, A; Kirk, JA; Houser, SR; Rainer, PP; Wallner, M Cardiomyocyte function and myofilament calcium sensitivity are altered by HDAC inhibition
EUR J HEART FAIL. 2021; 23: 307-307.-Heart Failure and World Congress on Acute Heart Failure European Society of Cardiology Heart Failure Association; JUN 29 - JUL , 2021; Nice, FRANCE. [Onlinepräsentation]
Web of Science

 

** Eaton, DM; Martin, TG; Kasa, M; Djalinac, N; Johnson, JP; Kolesnik, E; Ljubojevic-Holzer, S; von Lewinski, D; Maechler, H; Zirlik, A; Kirk, JA; Houser, SR; Rainer, PP; Wallner, M HDAC modification improves cardiomyocyte function via modulation of the myofilament
WIEN KLIN WOCHENSCHR. 2021; 133(SUPPL 3):S53-S53.-Jahrestagung der österreichischen kardiologischen Gesellschaft; May 27-29, 2021; [Onlinepräsentation]
Web of Science

 

** Eaton, DM; Martin, TG; Kasa, M; Djalinac, N; Johnson, JP; Kolesnik, E; Ljubojevic-Holzer, S; Von Lewinski, D; Maechler, H; Zirlik, A; Kirk, JA; Houser, SR; Rainer, PP; Wallner, M HDAC inhibition regulates cardiac function by increasing myofilament calcium sensitivity and decreasing diastolic tension
EUR J HEART FAIL. 2021; 23: 10-11. [Onlinepräsentation]
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** Holler, V; Zach, D; Kolesnik, E; Wallner, M; Fruhwald, F; Rainer, P; Zirlik, A; Verheyen, N Proportions and temporal trends of diseases leading to a hypertrophic cardiomyopathy phenotype. a prospective single-center cohort study
WIEN KLIN WOCHENSCHR. 2021; 133(SUPPL 3):S98-S98. [Onlinepräsentation]
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** Rech, L; Abdellatif, M; Poettler, M; Stangl, V; Ulcar, E; Ablasser, A; Rainer, PP STING inhibition in myocardial remodelling following myocardial infarction
EUR HEART J. 2021; 42: 3242-3242. [Poster]
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** Rech, L; Abdellatif, M; Pottler, M; Stangl, V; Ulcar, E; Gulen, M; Ablasser, A; Rainer, PP STING-Inhibition after myocardial infarction
WIEN KLIN WOCHENSCHR. 2021; 133(SUPPL 3): S57-S57. [Poster]
Web of Science

 

** Riepl, H; Wallner, M; Kolesnik, E; Ablasser, K; Rainer, P; Fruhwald, F; Zirlik, A; Kreuzer, P; Lueger, A; Verheyen, N Seasonal variation in decompensated heart failure in the emergency unit according to LVEF category-a retrospective analysis
WIEN KLIN WOCHENSCHR. 2021; 133(SUPPL 3):S115-S117. [Onlinepräsentation]
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** Riepl, H; Wallner, M; Kolesnik, E; Ablasser, K; Rainer, P; Fruhwald, F; Zirlik, A; Kreuzer, P; Lueger, A; Verheyen, N Seasonal variation in decompensated heart failure in the emergency unit according to LVEF category - a retrospective analysis
EUR J HEART FAIL. 2021; 23: 186-186. [Poster]
Web of Science

 

** Zsilavecz, VW; Ablasser, K; Rech, L; Stangl, V; Eller, P; Schilcher, G; Reisinger, A; Eller, K; Krause, R; Zirlik, A; Wallner, M; Rainer, P Cardiovascular disease and 6-month outcome of COVID-19 Inpatients at a tertiary referral centre
WIEN KLIN WOCHENSCHR. 2021; 133(SUPPL 3):S75-S76. [Poster]
Web of Science

 

Comment

** Schmid, J; Rainer, PP Reply to: More data about cardiac and neurologic findings would be useful.
ESC Heart Fail. 2021; 8(2):1729-1730 Doi: 10.1002/ehf2.13212 [OPEN ACCESS]
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2020

Full paper/article (Journal)

** Barbieri, F; Senoner, T; Adukauskaite, A; Dobner, S; Holfeld, J; Semsroth, S; Lambert, T; Zweiker, D; Theurl, T; Rainer, P; Schmidt, A; Feuchtner, G; Steinwender, C; Hoppe, U; Hintringer, F; Bauer, A; Müller, S; Grimm, M; Pfeifer, B; Dichtl, W Dataset on the prognostic value of cardiac biomarkers used in clinical routine in patients with severe aortic stenosis undergoing valve replacement.
Data Brief. 2020; 29:105111-105111 Doi: 10.1016/j.dib.2020.105111 [OPEN ACCESS]
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** Bonderman, D; Pölzl, G; Ablasser, K; Agis, H; Aschauer, S; Auer-Grumbach, M; Binder, C; Dörler, J; Duca, F; Ebner, C; Hacker, M; Kain, R; Kammerlander, A; Koschutnik, M; Kroiss, AS; Mayr, A; Nitsche, C; Rainer, PP; Reiter-Malmqvist, S; Schneider, M; Schwarz, R; Verheyen, N; Weber, T; Zaruba, MM; Badr Eslam, R; Hülsmann, M; Mascherbauer, J Diagnosis and treatment of cardiac amyloidosis: an interdisciplinary consensus statement.
Wien Klin Wochenschr. 2020; 132(23-24):742-761 Doi: 10.1007/s00508-020-01781-z [OPEN ACCESS]
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** de, Boer, RA; Hulot, JS; Tocchetti, CG; Aboumsallem, JP; Ameri, P; Anker, SD; Bauersachs, J; Bertero, E; Coats, AJS; Čelutkienė, J; Chioncel, O; Dodion, P; Eschenhagen, T; Farmakis, D; Bayes-Genis, A; Jäger, D; Jankowska, EA; Kitsis, RN; Konety, SH; Larkin, J; Lehmann, L; Lenihan, DJ; Maack, C; Moslehi, JJ; Müller, OJ; Nowak-Sliwinska, P; Piepoli, MF; Ponikowski, P; Pudil, R; Rainer, PP; Ruschitzka, F; Sawyer, D; Seferovic, PM; Suter, T; Thum, T; van, der, Meer, P; Van, Laake, LW; von, Haehling, S; Heymans, S; Lyon, AR; Backs, J Common mechanistic pathways in cancer and heart failure. A scientific roadmap on behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC).
Eur J Heart Fail. 2020; 22(12):2272-2289 Doi: 10.1002/ejhf.2029 [OPEN ACCESS]
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** Deak, AT; Ionita, F; Kirsch, AH; Odler, B; Rainer, PP; Kramar, R; Kubatzki, MP; Eberhard, K; Berghold, A; Rosenkranz, AR Impact of cardiovascular risk stratification strategies in kidney transplantation over time.
Nephrol Dial Transplant. 2020; 35(10): 1810-1818. Doi: 10.1093/ndt/gfaa131 [OPEN ACCESS]
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** Djalinac, N; Ljubojevic-Holzer, S; Matzer, I; Kolesnik, E; Jandl, K; Lohberger, B; Rainer, P; Heinemann, A; Sedej, S; von, Lewinski, D; Bisping, E The role of stretch, tachycardia and sodium-calcium exchanger in induction of early cardiac remodelling.
J Cell Mol Med. 2020; 24(15):8732-8743 Doi: 10.1111/jcmm.15504 [OPEN ACCESS]
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** Koyani, CN; Plastira, I; Sourij, H; Hallström, S; Schmidt, A; Rainer, PP; Bugger, H; Frank, S; Malle, E; von, Lewinski, D Empagliflozin protects heart from inflammation and energy depletion via AMPK activation.
Pharmacol Res. 2020; 158:104870 Doi: 10.1016/j.phrs.2020.104870
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** Prasch, J; Bernhart, E; Reicher, H; Kollroser, M; Rechberger, GN; Koyani, CN; Trummer, C; Rech, L; Rainer, PP; Hammer, A; Malle, E; Sattler, W Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro.
Int J Mol Sci. 2020; 21(23): Doi: 10.3390/ijms21239235 [OPEN ACCESS]
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** Ranek, MJ; Oeing, C; Sanchez-Hodge, R; Kokkonen-Simon, KM; Dillard, D; Aslam, MI; Rainer, PP; Mishra, S; Dunkerly-Eyring, B; Holewinski, RJ; Virus, C; Zhang, H; Mannion, MM; Agrawal, V; Hahn, V; Lee, DI; Sasaki, M; Van Eyk, JE; Willis, MS; Page, RC; Schisler, JC; Kass, DA CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury.
Nat Commun. 2020; 11(1): 5237-5237. Doi: 10.1038/s41467-020-18980-x [OPEN ACCESS]
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** Schmid, J; Beer, M; Berghold, A; Stojakovic, T; Scharnagl, H; Dieplinger, B; Quasthoff, S; Binder, JS; Rainer, PP Cardiac involvement in a cross-sectional cohort of myotonic dystrophies and other skeletal myopathies.
ESC Heart Fail. 2020; 7(4):1900-1908 Doi: 10.1002/ehf2.12763 [OPEN ACCESS]
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** Wakabayashi, I; Eguchi, R; Sotoda, Y; von Lewinski, D; Sourij, H; Daimon, T; Groschner, K; Rainer, PP Blood levels of microRNAs associated with ischemic heart disease differ between Austrians and Japanese: a pilot study.
Sci Rep. 2020; 10(1): 13628-13628. Doi: 10.1038/s41598-020-69332-0 [OPEN ACCESS]
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** Wallner, M; Eaton, DM; Berretta, RM; Liesinger, L; Schittmayer, M; Gindlhuber, J; Wu, J; Jeong, MY; Lin, YH; Borghetti, G; Baker, ST; Zhao, H; Pfleger, J; Blass, S; Rainer, PP; von Lewinski, D; Bugger, H; Mohsin, S; Graier, WF; Zirlik, A; McKinsey, TA; Birner-Gruenberger, R; Wolfson, MR; Houser, SR HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.
Sci Transl Med. 2020; 12(525): Doi: 10.1126/scitranslmed.aay7205 [OPEN ACCESS]
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Correspondence

** Rainer, PP The pulse of fibroblasts: circadian rhythm in pulmonary fibrosis development.
Cardiovasc Res. 2020; 116(11): e134-e135-e134-e135. Doi: 10.1093/cvr/cvaa236 [OPEN ACCESS]
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Abstract (Journal)

** Barbieri, F; Senoner, T; Adukauskaite, A; Lambert, T; Zweiker, D; Rainer, P; Schmidt, A; Feuchtner, G; Steinwender, C; Hoppe, U; Hintringer, F; Bauer, A; Mueller, S; Grimm, M; Dichtl, W The prognostic value of preprocedural high-sensitivity troponin T in patients with severe aortic stenosis undergoing valve replacement: a gender analysis.
EUR HEART J. 2020; 41: 1984-1984. [Poster]
Web of Science

 

** Djalinac, N; Kolesnik, E; Maechler, H; Sedej, S; Rainer, P; Scher, D; Heinemann, A; Von Lewinski, D; Bisping, E MIR1183 as a new tissue biomarker with triggered acute response and upregulation in chronic atrial and ventricular remodeling.
EUR HEART J. 2020; 41: 3662-3662. [Poster]
Web of Science

 

** Eaton, D; Kasa, M; Abdellatif, M; Ljubojevic-Holzer, S; Zugner, E; Magnes, C; Sourij, H; von Lewinski, D; Rainer, P; Angleitner, P; Zuckermann, A; Aliabadi-Zuckermann, A; Zirlik, A; Pieber, T; Houser, SR; Wallner, M Metabolic effects of HDAC inhibition in a feline model of HFpEF.
WIEN KLIN WOCHENSCHR. 2020; 132: S163-S164. [Poster]
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** Kasa, M; Eaton, D; Ljubojevic-Holzer, S; Koyani, C; von Lewinski, D; Zirlik, A; Angleitner, P; Zuckermann, A; Aliabadi-Zuckermann, A; Houser, SR; Rainer, P; Wallner, M Effects of pan-HDAC inhibition on Ca2+-cycling and sarcomere-kinetics.
WIEN KLIN WOCHENSCHR. 2020; 132: S257-S258. [Poster]
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** Knierim, M; Pabel, S; Paulus, M; Rainer, P; Scherr, D; Hasenfuss, G; Maier, L; Streckfuss-Boemeke, K; Sossalla, S Cellular mechanisms of early tachycardia-induced ventricular dysfunction in the human heart.
EUR HEART J. 2020; 41: 3680-3680. [Poster]
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** Zsilavecz, VW; Ablasser, K; Rech, L; Stangl, V; Kaufmann, F; Reichel, KT; Eller, P; Schilcher, G; Reisinger, A; Muster, V; Brodmann, M; Gutl, K; Krause, R; Pieber, T; Zirlik, A; Wallner, M; Rainer, P Cardiovascular characteristics and intra-hospital outcome of COVID-19 inpatients at a tertiary referral centre.
WIEN KLIN WOCHENSCHR. 2020; 132: S182-S183. [Poster]
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2019

Full paper/article (Journal)

** Barbieri, F; Senoner, T; Adukauskaite, A; Dobner, S; Holfeld, J; Semsroth, S; Lambert, T; Zweiker, D; Theurl, T; Rainer, PP; Schmidt, A; Feuchtner, GM; Steinwender, C; Hoppe, UC; Hintringer, F; Bauer, A; Müller, S; Grimm, M; Pfeifer, BE; Dichtl, W Long-Term Prognostic Value of High-Sensitivity Troponin T Added to N-Terminal Pro Brain Natriuretic Peptide Plasma Levels Before Valve Replacement for Severe Aortic Stenosis.
Am J Cardiol. 2019; 124(12): 1932-1939. Doi: 10.1016/j.amjcard.2019.09.014
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** Hardy, SA; Mabotuwana, NS; Murtha, LA; Coulter, B; Sanchez-Bezanilla, S; Al-Omary, MS; Senanayake, T; Loering, S; Starkey, M; Lee, RJ; Rainer, PP; Hansbro, PM; Boyle, AJ Novel role of extracellular matrix protein 1 (ECM1) in cardiac aging and myocardial infarction.
PLoS One. 2019; 14(2): e0212230-e0212230. Doi: 10.1371/journal.pone.0212230 [OPEN ACCESS]
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** Kolesnik, E; Krainer, T; Wallner, M; Djalinac, N; Verheyen, N; Ablasser, K; Eaton, DM; Rainer, PP; Pelzmann, B; von Lewinski, D Myocardial GLP-1 Receptor Activation in the Presence of Glucose: Strong Partners
INT J PEPT RES THER. 2019; 25(2): 605-612. Doi: 10.1007/s10989-018-9706-9 [OPEN ACCESS]
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Review

** Ablasser, K; Verheyen, N; Glantschnig, T; Agnetti, G; Rainer, PP Unfolding Cardiac Amyloidosis -From Pathophysiology to Cure.
Curr Med Chem. 2019; 26(16):2865-2878 Doi: 10.2174/0929867325666180104153338
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Abstract (Journal)

** Abdellatif, M; Herbst, V; Schmidt, A; Humnig, A; Pendl, T; Gross, A; Hofer, S; Madeo, F; Zirlik, A; Scherr, D; von Lewinski, D; Rainer, P; McMullen, J; Eisenberg, T; Bisping, E; Sedej, S Life stage determines the dual effects of IGF1 signalling on cardiac health and survival
WIEN KLIN WOCHENSCHR. 2019; 131: 250-250. [Oral Communication]
Web of Science

 

** Barbieri, F; Senoner, T; Adukauskaite, A; Dobner, S; Holfeld, J; Semsroth, S; Lambert, T; Zweiker, D; Theurl, T; Rainer, P; Schmidt, A; Feuchtner, G; Steinwender, C; Hoppe, U; Hintringer, F; Muller, S; Grimm, M; Pfeifer, B; Dichtl, W Combined biomarker risk stratification with high-sensitivity troponin T and N-terminal pro brain natriuretic peptide in 3595 patients with severe aortic stenosis admitted for valve replacement
WIEN KLIN WOCHENSCHR. Abstracts 47. Jahrestagung der Österreichischen Diabetes Gesellschaft. 2019; 131: S448-S448.-47. Jahrestagung der Österreichischen Diabetes Gesellschaft; NOV 21-23, 2019; Salzburg, Austria. [Poster]
Web of Science

 

** Barbieri, F; Senoner, T; Holfeld, J; Semsroth, S; Lambert, T; Zweiker, D; Theurl, T; Rainer, PP; Schmidt, A; Feuchtner, GM; Steinwender, C; Hoppe, U; Mueller, S; Grimm, M; Dichtl, W High sensitivity troponin t and n-terminal pro brain natriuretic peptide plasma levels predict long-term postoperative survival in patients with severe aortic stenosis admitted for valve implantation
EUR HEART J. 2019; 40: 2875-2875. [Poster]
Web of Science

 

** Deak, A; Francesca, I; Odler, B; Kramar, R; Rainer, P; Eberhard, K; Berghold, A; Rosenkranz, A RETROSPECTIVE EVALUATION OF CARDIOVASCULAR RISK STRATIFICATION PRIOR TO KIDNEY TRANSPLANTATION
NEPHROL DIAL TRANSPL. 2019; 34: [Poster]
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** Djalinac, N; Kolesnik, E; Koyani, C; Machler, H; Bisping, E; Sourij, H; Rainer, P; Pelzmann, B; von Lewinski, D SGLT2 inhibitors exert no functional effects on healthy human myocardium
WIEN KLIN WOCHENSCHR. 2019; 131: 336-337. [Poster]
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** Eaton, DM; Wallner, M; Berretta, RM; Bordag, N; Wu, JC; Jeong, MY; Lin, YH; Borghetti, G; Baker, ST; Zhao, HQ; Rainer, PP; Oyama, MA; von Lewinski, D; Mohsin, S; Post, H; Magnes, C; Zugner, E; McKinsey, TA; Wolfson, MR; Houser, SR Histone Deacetylase Inhibition Improves Heart Failure With Preserved Ejection Fraction Cardiopulmonary Phenotype and Induces Metabolomic Switch
CIRC RES. 2019; 125: [Poster]
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** Glantschnig, T; Posch, F; Firla, S; Moik, F; Ablasser, K; Binder, JS; Stoschitzky, G; Wallner, M; Von Lewinski, D; Stoger, H; Zirlik, A; Pichler, M; Rainer, PP Clinical utility of echocardiographic left-ventricular ejection fraction monitoring for cardiotoxicity risk assessment in patients with HER2+early breast cancer undergoing trastuzumab-based therapy
WIEN KLIN WOCHENSCHR. 2019; 131: 292-293. [Poster]
Web of Science

 

** Hardy, S; Mabotuwana, NS; Murtha, LA; Coulter, B; Bezenilla, SS; Al-Omary, MS; Senanayake, T; Loering, S; Rech, CLS; Starkey, M; Lee, RJ; Rainer, P; Hansbro, PM; Boyle, AJ The role of extracellular matrix protein 1 (ECM1) - a novel link between inflammation and cardiac fibrosis
EUR HEART J. 2019; 40: 3900-3900. [Poster]
Web of Science

 

** Posch, F; Glantschnig, T; Firla, S; Smolle, M; Balic, M; Moik, F; Stoeger, H; Zirlik, A; Pichler, M; Rainer, P Clinical utility of echocardiographic left-ventricular ejection fraction monitoring for cardiotoxicity risk assessment in patients with HER2+early breast cancer undergoing trastuzumab-based therapy
EUR HEART J. 2019; 40: 3844-3844.-ESC Congress / World Congress of Cardiology; AUG 31-SEP 04, 2019; Paris, FRANCE. [Poster]
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** Wallner, M; Eaton, D; Berretta, R; Bordag, N; Wu, JC; Jeong, M; Lin, Y; Borghetti, G; Zhao, HQ; Rainer, P; von Lewinski, D; Mohsin, S; Zugner, E; Blass, S; Graier, W; Zirlik, A; McKinsey, T; Wolfson, M; Houser, S HDAC inhibition improves myofibrillar relaxation and metabolism in a feline model of HFpEF
WIEN KLIN WOCHENSCHR. 2019; 131: 254-255.-Jahrestagung der Österreichischen Kardiologischen Gesellschaft; MAY 29-JUN 1, 2019; Salzburg, AUSTRIA. [Poster]
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** Wallner, M; Eaton, D; Berretta, R; Wu, J; Jeong, M; Zhao, H; Rainer, P; Blass, S; Von Lewinski, D; Zuegner, E; Zirlik, A; Graier, W; McKinsey, T; Wolfson, M; Houser, S HDAC inhibition improves myofibrillar relaxation and metabolism in a feline model of HFpEF
EUR HEART J. 2019; 40: 3677-3677. [Poster]
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2018

Full paper/article (Journal)

** Glöcklhofer, CR; Steinfurt, J; Franke, G; Hoppmann, A; Glantschnig, T; Perez-Feliz, S; Alter, S; Fischer, J; Brunner, M; Rainer, PP; Köttgen, A; Bode, C; Odening, KE A novel LMNA nonsense mutation causes two distinct phenotypes of cardiomyopathy with high risk of sudden cardiac death in a large five-generation family.
Europace. 2018; 20(12):2003-2013 Doi: 10.1093/europace/euy127
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** Koyani, CN; Trummer, C; Shrestha, N; Scheruebel, S; Bourgeois, B; Plastira, I; Kickmaier, S; Sourij, H; Rainer, PP; Madl, T; Sattler, W; Pelzmann, B; Malle, E; von Lewinski, D Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes.
Front Physiol. 2018; 9:1622-1622 Doi: 10.3389/fphys.2018.01622 [OPEN ACCESS]
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** Muster, V; Wallner, M; Schmidt, A; Kapl, M; von Lewinski, F; Rainer, P; Reittner, P; Tillich, M; Brader, P; Szolar, DH; von Lewinski, D Heart rate-reducing therapy with add-on ivabradine and bisoprolol before coronary computed tomographic angiography in a fast-track ambulatory setting.
J Int Med Res. 2018; 46(6):2249-2257 Doi: 10.1177/0300060518761302 [OPEN ACCESS]
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** Prüller, F; Milke, OL; Bis, L; Fruhwald, F; Scherr, D; Eller, P; Pätzold, S; Altmanninger-Sock, S; Rainer, P; Siller-Matula, J; von Lewinski, D Impaired aspirin-mediated platelet function inhibition in resuscitated patients with acute myocardial infarction treated with therapeutic hypothermia: a prospective, observational, non-randomized single-centre study.
Ann Intensive Care. 2018; 8(1):28-28 Doi: 10.1186/s13613-018-0366-x [OPEN ACCESS]
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** Rainer, PP; Dong, P; Sorge, M; Fert-Bober, J; Holewinski, RJ; Wang, Y; Foss, CA; An, SS; Baracca, A; Solaini, G; Glabe, CG; Pomper, MG; Van Eyk, JE; Tomaselli, GF; Paolocci, N; Agnetti, G Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure.
Circ Res. 2018; 122(10): e75-e83-e75-e83. Doi: 10.1161/CIRCRESAHA.117.312082 [OPEN ACCESS]
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** Schmid, J; Liesinger, L; Birner-Gruenberger, R; Stojakovic, T; Scharnagl, H; Dieplinger, B; Asslaber, M; Radl, R; Beer, M; Polacin, M; Mair, J; Szolar, D; Berghold, A; Quasthoff, S; Binder, JS; Rainer, PP Elevated Cardiac Troponin T in Patients With Skeletal Myopathies.
J Am Coll Cardiol. 2018; 71(14):1540-1549 Doi: 10.1016/j.jacc.2018.01.070 [OPEN ACCESS]
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** Schneider, C; Wallner, M; Kolesnik, E; Herbst, V; Mächler, H; Pichler, M; von Lewinski, D; Sedej, S; Rainer, PP The Anti-Cancer Multikinase Inhibitor Sorafenib Impairs Cardiac Contractility by Reducing Phospholamban Phosphorylation and Sarcoplasmic Calcium Transients.
Sci Rep. 2018; 8(1):5295-5295 Doi: 10.1038/s41598-018-23630-w [OPEN ACCESS]
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Abstract (Journal)

** Deak, AT; Ionita, F; Rainer, P; Eberhard, K; Berghold, A; Rosenkranz, AR RETROSPECTIVE EVALUATION OF CARDIOVASCULAR RISK STRATIFICATION PRIOR TO KIDNEY TRANSPLANTATION.
TRANSPL INT. 2018; 31: 15-15.-AUSTROTRANSPLANT 2018; OCT 17-19, 2018; Linz, AUSTRIA. [Oral Communication]
Web of Science

 

** Kolesnik, E; Kapeller, S; Wallner, M; Rainer, PP;, Abdellatif, M; Maechler, H; Sedej, S; Von Lewinski D Acute administration of high levels of spermidine and spermine impair ryanodine receptor type 2-dependent contractility in human atrial tissue
European Journal of Heart Failure. 2018; 20(S1):630-630.-ESC Heart Failure 2018; MAY 26-29, 2018; Vienna, Austria. [Poster]
Web of Science

 

** Taucher, V; Rainer, P; Ablasser, K; Berghaus, TM; Zechner, P; Weihs, W; Muster, A; von Lewinski, D Analysis of the Association of Air Pollution and the Incidence of Acute Coronary Syndrome and Myocardial Infarction in a large Cohort in Greater Graz, Styria
WIEN KLIN WOCHENSCHR. 2018; 130: 22-22.-ÖKG; Salzburg, AUSTRIA. [Poster]
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** Taucher, V; Rainer, P; Ablasser, K; Berghaus, TM; Zechner, P; Weihs, W; Muster, A; Von Lewinski, D Association analysis of air polution on acute coronary syndrome and myocardial infarction in a large cohort
EUR HEART J. 2018; 39: 499-499.
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** Zweiker, D; Hatz, D; Schmid, J; Binder, J; Maier, R; Luha, O; Schmidt, A; Scherr, D; Rainer, P Invasive vs echocardiographic systolic pulmonary artery pressure for risk assessment in TAVI patients
WIEN KLIN WOCHENSCHR. 2018; 130: 16-16. [Poster]
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** Zweiker, D; Hatz, D; Schmid, J; Binder, J; Maier, R; Luha, O; Schmidt, A; Scherr, D; Rainer, P The new STS/ACC TAVI risk score and long-term outcome in TAVI patients
WIEN KLIN WOCHENSCHR. 2018; 130: 71-72. [Poster]
Web of Science

 

Abstract (Proceedings)

** Glantschnig, T; Ablasser, K; Verheyen, N; von Lewinski, D; Rainer, PP What may happen when you are expecting - a case of peripartum cardiomyopathy
Eur J Heart Failure. 2018; 20(S1):358-358.-Heart Failure Association ESC; MAY 26-29, 2018; Vienna, AUSTRIA. [Poster]
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Comment

** Schmid, J; Birner-Grünberger, R; Quasthoff, S; Binder, JS; Rainer, PP Reply: Elevated Cardiac Troponin T in Skeletal Myopathies: Skeletal TnT Cross-Reactivity and/or Cardiac TnT Expression?
J Am Coll Cardiol. 2018; 72(3):349-350 Doi: 10.1016/j.jacc.2018.05.019 [OPEN ACCESS]
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2017

Full paper/article (Journal)

** Evilä, A; Palmio, J; Vihola, A; Savarese, M; Tasca, G; Penttilä, S; Lehtinen, S; Jonson, PH; De Bleecker, J; Rainer, P; Auer-Grumbach, M; Pouget, J; Salort-Campana, E; Vilchez, JJ; Muelas, N; Olive, M; Hackman, P; Udd, B Targeted Next-Generation Sequencing Reveals Novel TTN Mutations Causing Recessive Distal Titinopathy.
Mol Neurobiol. 2017; 54(9):7212-7223 Doi: 10.1007/s12035-016-0242-3 [OPEN ACCESS]
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** Frauscher, B; Artinger, K; Kirsch, AH; Aringer, I; Moschovaki-Filippidou, F; Kétszeri, M; Schabhüttl, C; Rainer, PP; Schmidt, A; Stojakovic, T; Fahrleitner-Pammer, A; Rosenkranz, AR; Eller, P; Eller, K A New Murine Model of Chronic Kidney Disease-Mineral and Bone Disorder.
Int J Endocrinol. 2017; 2017(3):1659071-1659071 Doi: 10.1155/2017/1659071 [OPEN ACCESS]
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** Koyani, CN; Kolesnik, E; Wölkart, G; Shrestha, N; Scheruebel, S; Trummer, C; Zorn-Pauly, K; Hammer, A; Lang, P; Reicher, H; Maechler, H; Groschner, K; Mayer, B; Rainer, PP; Sourij, H; Sattler, W; Malle, E; Pelzmann, B; von, Lewinski, D Dipeptidyl peptidase-4 independent cardiac dysfunction links saxagliptin to heart failure.
Biochem Pharmacol. 2017; 145:64-80 Doi: 10.1016/j.bcp.2017.08.021 [OPEN ACCESS]
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** Rouf, R; MacFarlane, EG; Takimoto, E; Chaudhary, R; Nagpal, V; Rainer, PP; Bindman, JG; Gerber, EE; Bedja, D; Schiefer, C; Miller, KL; Zhu, GS; Myers, L; Amat-Alarcon, N; Lee, DI; Koitabashi, N; Judge, DP; Kass, DA; Dietz, HC Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice
JCI INSIGHT. 2017; 2(15): e91588 Doi: 10.1172/jci.insight.91588 [OPEN ACCESS]
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** Schmid, J; Stojakovic, T; Zweiker, D; Scharnagl, H; Maderthaner, RD; Scherr, D; Maier, R; Schmidt, A; März, W; Binder, JS; Rainer, PP ST2 predicts survival in patients undergoing transcatheter aortic valve implantation.
Int J Cardiol. 2017; 244(23-24):87-92 Doi: 10.1016/j.ijcard.2017.06.066
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** Wallner, M; Khafaga, M; Kolesnik, E; Vafiadis, A; Schwantzer, G; Eaton, DM; Curcic, P; Köstenberger, M; Knez, I; Rainer, PP; Pichler, M; Pieske, B; Lewinski, DV Istaroxime, a potential anticancer drug in prostate cancer, exerts beneficial functional effects in healthy and diseased human myocardium.
Oncotarget. 2017; 8(30):49264-49274 Doi: 10.18632/oncotarget.17540 [OPEN ACCESS]
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Abstract (Journal)

** Krainer, T; Kolesnik, E; Wallner, M; Djalinac, N; Koyani, C; Machler, H; Rainer, P; Pelzmann, B; von Lewinski, D; The positive Inotropic effect of GLP 1 receptor activation is influenced by the presence of glucose.
WIEN KLIN WOCHENSCHR. 2017; 129: S24-S25.-Jahrestagung der Österreichischen Gesellschaft für Kardiologie; JUN 6-9, 2017; Salzburg, AUSTRIA. [Poster]
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2016

Full paper/article (Journal)

** Kooij, V; Viswanathan, MC; Lee, DI; Rainer, PP; Schmidt, W; Kronert, WA; Harding, SE; Kass, DA; Bernstein, SI; Van Eyk, JE; Cammarato, A Profilin modulates sarcomeric organization and mediates cardiomyocyte hypertrophy.
Cardiovasc Res. 2016; 110(2):238-248 Doi: 10.1093/cvr/cvw050 [OPEN ACCESS]
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** Sysa-Shah, P; Tocchetti, CG; Gupta, M; Rainer, PP; Shen, X; Kang, BH; Belmonte, F; Li, J; Xu, Y; Guo, X; Bedja, D; Gao, WD; Paolocci, N; Rath, R; Sawyer, DB; Naga Prasad, SV; Gabrielson, K Bidirectional cross-regulation between ErbB2 and β-adrenergic signalling pathways.
Cardiovasc Res. 2016; 109(3):358-373 Doi: 10.1093/cvr/cvv274 [OPEN ACCESS]
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Review

** Rainer, PP; Kass, DA Old dog, new tricks: novel cardiac targets and stress regulation by protein kinase G.
Cardiovasc Res. 2016; 111(2):154-162 Doi: 10.1093/cvr/cvw107 [OPEN ACCESS]
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Case Report

** Maier, R; Krumnikl, J; Knez, I; Rainer, PP Typical STEMI: or not? Embolic left anterior descending artery occlusion, fulminant pulmonary embolism, and in-transit thrombus in a patent foramen ovale.
Eur Heart J. 2016; 37(40): 3114-3114. Doi: 10.1093/eurheartj/ehw258 [OPEN ACCESS]
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Abstract (Journal)

** Glantschnig T; Glöcklhofer C; Ablasser K; Zuckermann A; von Lewinski D; Odenig KE; Fruhwald FM; Rainer PP Acute fulminant heart failure in a 32-year old male due to an inherited lamin A/C mutation.
Eur Heart J. 2016; 37(Suppl ):1425-1425.-European Society of Cardiology 2016; AUG 27-31, 2016; Rome, ITALY. [Oral Communication]
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** Glantschnig, T; Gloecklhofer, C; Ablasser, K; Zuckermann, A; von Lewinski, D; Odening, KE; Fruhwald, FM; Rainer, PP Acute fulminant heart failure in a 32 year-old male due to an inherited Lamin A/C mutation
WIEN KLIN WOCHENSCHR. Wiener Klinische Wochenschrift. 2016; 128(Supp 3):S321-S322.-Jahrestagung der Österreichischen Kardiologischen Gesellschaft; JUN 1-4, 2016; Salzburg, AUSTRIA. [Poster]
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** Kapeller, S; Kolesnik, E; Wallner, M; Rainer, P; Sedej, S; von Lewinski, D High levels of spermidine and spermine cause impaired force development, arrhythmias and negative inotropy in human atrial tissue
WIEN KLIN WOCHENSCHR. 2016; 128: S310-S311. [Poster]
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** Rainer, PP; Lee, DI; Sorge, M; Glabe, C; Paolocci, N; Guarnieri, C; Tomaselli, GF; Kass, DA; Van Eyk, J; Agnetti, G Differential phosphorylation of desmin at serines 27 and 31 drives the accumulation of preamyloid oligomers in heart failure
Cardiovasc Res. 2016; 111(1):S39--Frontiers in Cardiovascular Biology; JUL 8-10, 2016; Florence, Italy. [Poster]
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** Schneider, C; Wallner, M; Abdellatif, M; von Lewinski, D; Pichler, M; Sedej, S; Rainer, P The anti-cancer tyrosine kinase inhibitor sorafenib reduces cardiac contractile force by reducing cardiomyocyte calcium transient amplitude
WIEN KLIN WOCHENSCHR. 2016; 128: S309-S310. [Poster]
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2015

Full paper/article (Journal)

** Chung, HS; Murray, CI; Venkatraman, V; Crowgey, EL; Rainer, PP; Cole, RN; Bomgarden, RD; Rogers, JC; Balkan, W; Hare, JM; Kass, DA; Van Eyk, JE Dual Labeling Biotin Switch Assay to Reduce Bias Derived From Different Cysteine Subpopulations: A Method to Maximize S-Nitrosylation Detection.
Circ Res. 2015; 117(10):846-857 Doi: 10.1161/CIRCRESAHA.115.307336 [OPEN ACCESS]
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** Lee, DI; Zhu, G; Sasaki, T; Cho, GS; Hamdani, N; Holewinski, R; Jo, SH; Danner, T; Zhang, M; Rainer, PP; Bedja, D; Kirk, JA; Ranek, MJ; Dostmann, WR; Kwon, C; Margulies, KB; Van Eyk, JE; Paulus, WJ; Takimoto, E; Kass, DA Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease.
Nature. 2015; 519(7544):472-476 Doi: 10.1038/nature14332 [OPEN ACCESS]
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Abstract (Journal)

** Rainer, P; Lee, DI; Sorge, M; Guarnieri, C; Glabe, CG; O'Rourke, B; Tomaselli, GF; Kass, DA; Van Eyk, JE; Agnetti, G Desmin Preamyloid Oligomers in Experimental Heart Failure and Cultured Cardiac Myocytes
CIRC RES. 2015; 117:
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** Rainer, PP; Lee, DI; Sorge, M; Baracca, A; Solaini, G; Guarnieri, C; Glabe, CG; Paolocci, N; O'Rourke, B; Tomaselli, GF; Kass, DA; Van Eyk, JE; Agnetti, G Modified desmin pre-amyloid oligomers are increased in experimental heart failure.
VASC PHARMACOL. 2015; 75: 40-40. Doi: 10.1016/j.vph.2015.11.003 [Oral Communication]
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** Rainer, PP; Toth, GG; Knez, I; Sacherer, M; Krumnikl, J; Wiesspeiner, U; Brussee, H; Maier, RM Typical STEMI - or not: embolic LAD occlusion and fulminant pulmonary embolism with in-transit thrombus in a patent foramen ovale
EUR HEART J. 2015; 36: 1218-1219.-Congress of the European-Society-of-Cardiology (ESC); AUG 29-SEP 02, 2015; London, ENGLAND. [Oral Communication]
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Comment

** Kass, DA; Seo, K; Rainer, P Response to letter from Villa-Abrille et al.
Circ Res. 2015; 116(1): e12-e12. Doi: 10.1161/CIRCRESAHA.114.305576 [OPEN ACCESS]
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2014

Full paper/article (Journal)

** Rainer, PP; Hao, S; Vanhoutte, D; Lee, DI; Koitabashi, N; Molkentin, JD; Kass, DA Cardiomyocyte-specific transforming growth factor β suppression blocks neutrophil infiltration, augments multiple cytoprotective cascades, and reduces early mortality after myocardial infarction.
Circ Res. 2014; 114(8):1246-1257 Doi: 10.1161/CIRCRESAHA.114.302653 [OPEN ACCESS]
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** Seo, K; Rainer, PP; Lee, DI; Hao, S; Bedja, D; Birnbaumer, L; Cingolani, OH; Kass, DA Hyperactive adverse mechanical stress responses in dystrophic heart are coupled to transient receptor potential canonical 6 and blocked by cGMP-protein kinase G modulation.
Circ Res. 2014; 114(5):823-832 Doi: 10.1161/CIRCRESAHA.114.302614 [OPEN ACCESS]
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** Seo, K; Rainer, PP; Shalkey Hahn, V; Lee, DI; Jo, SH; Andersen, A; Liu, T; Xu, X; Willette, RN; Lepore, JJ; Marino, JP; Birnbaumer, L; Schnackenberg, CG; Kass, DA Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.
Proc Natl Acad Sci U S A. 2014; 111(4):1551-1556 Doi: 10.1073/pnas.1308963111 [OPEN ACCESS]
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** Shenje, LT; Andersen, P; Uosaki, H; Fernandez, L; Rainer, PP; Cho, GS; Lee, DI; Zhong, W; Harvey, RP; Kass, DA; Kwon, C Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors.
Elife. 2014; 3(5):e02164-e02164 Doi: 10.7554/eLife.02164 [OPEN ACCESS]
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2013

Full paper/article (Journal)

** Rainer, PP; Primessnig, U; Harenkamp, S; Doleschal, B; Wallner, M; Fauler, G; Stojakovic, T; Wachter, R; Yates, A; Groschner, K; Trauner, M; Pieske, BM; von Lewinski, D Bile acids induce arrhythmias in human atrial myocardium--implications for altered serum bile acid composition in patients with atrial fibrillation.
Heart. 2013; 99(22):1685-1692 Doi: 10.1136/heartjnl-2013-304163
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** Sivakumaran, V; Stanley, BA; Tocchetti, CG; Ballin, JD; Caceres, V; Zhou, L; Keceli, G; Rainer, PP; Lee, DI; Huke, S; Ziolo, MT; Kranias, EG; Toscano, JP; Wilson, GM; O'Rourke, B; Kass, DA; Mahaney, JE; Paolocci, N HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.
Antioxid Redox Signal. 2013; 19(11):1185-1197 Doi: 10.1089/ars.2012.5057 [OPEN ACCESS]
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2012

Full paper/article (Journal)

** Larson, JE; Rainer, PP; Watts, VL; Yang, R; Miller, KL; Phan, A; Barouch, LA Dependence of β3-adrenergic signaling on the adipokine leptin in cardiac myocytes.
Int J Obes (Lond). 2012; 36(6):876-879 Doi: 10.1038/ijo.2011.137 [OPEN ACCESS]
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** Pichler, M; Rainer, PP; Schauer, S; Hoefler, G Cardiac fibrosis in human transplanted hearts is mainly driven by cells of intracardiac origin.
J Am Coll Cardiol. 2012; 59(11): 1008-1016. Doi: 10.1016/j.jacc.2011.11.036 [OPEN ACCESS]
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** Rainer, PP; Doleschal, B; Kirk, JA; Sivakumaran, V; Saad, Z; Groschner, K; Maechler, H; Hoefler, G; Bauernhofer, T; Samonigg, H; Hutterer, G; Kass, DA; Pieske, B; von, Lewinski, D; Pichler, M Sunitinib causes dose-dependent negative functional effects on myocardium and cardiomyocytes.
BJU Int. 2012; 110(10):1455-62 Doi: 10.1111/j.1464-410X.2012.11134.x [OPEN ACCESS]
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Editorial

** Rainer, PP; Schmidt, A; Anelli-Monti, M; Kleinert, R; Pieske, BM; Maier, RM; A Swinging Pacemaker Lead Promoting Endocarditis and Severe Tricuspid Regurgitation.
J Am Coll Cardiol. 2012; 59(23):e45-e45 Doi: 10.1016/j.jacc.2011.10.908 (- Case Report) [OPEN ACCESS]
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2011

Full paper/article (Journal)

** Rainer, PP; Kaufmann, P; Smolle-Juettner, FM; Krejs, GJ Case report: Hyperbaric oxygen in the treatment of puff adder (Bitis arietans) bite
Undersea Hyperb Med. 2011; 37(6):395-398 (- Case Report)
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2010

Full paper/article (Journal)

** Rainer, PP; Eherer, A; Langner, C; Graninger, WB; Spreizer, C; Weber, K Esophageal ulceration mimicking malignancy in a patient with severe kyphoscoliosis.
Endoscopy. 2010; 42 Suppl 2:E119-E120 Doi: 10.1055/s-0029-1243991 (- Case Report) [OPEN ACCESS]
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** von Lewinski, D; Gasser, R; Rainer, PP; Huber, MS; Wilhelm, B; Roessl, U; Haas, T; Wasler, A; Grimm, M; Bisping, E; Pieske, B Functional effects of glucose transporters in human ventricular myocardium.
Eur J Heart Fail. 2010; 12(2):106-113 Doi: 10.1093/eurjhf/hfp191 [OPEN ACCESS]
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** von Lewinski, D; Rainer, PP; Gasser, R; Huber, MS; Khafaga, M; Wilhelm, B; Haas, T; Mächler, H; Rössl, U; Pieske, B Glucose-transporter-mediated positive inotropic effects in human myocardium of diabetic and nondiabetic patients.
Metabolism. 2010; 59(7):1020-1028 Doi: 10.1016/j.metabol.2009.10.025
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Abstract (Journal)

** Gasser, R; Holzwart, E; Rainer, PP; Von Lewinski, D; Maechler, H; Gasser, S; Roessl, U; Pieske, BM Shift from adult to fetal metabolic phenotype during experimental ischemia reiterates the epigenetic plasticity of the molecular networks associated with myocardial metabolism in the aging heart
CARDIOVASC RES. 2010; 87: S115-S115. [Poster]
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** Gasser, S; Rainer, PP; Holzwart, E; Roessl, U; Kraigher-Krainer, E; Von Lewinksi, D; Pieske, BM; Gasser, R PDK (Pyruvate dehydrogenase kinase) is differentially regulated by beta-blockers in experimental myocardial hypoxia
CARDIOVASC RES. 2010; 87: S116-S116. [Poster]
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** Rainer, PP; Eherer, A; Langner, C; Graninger, WB; Weber K Esophageal ulceration in a patient with kyphoscoliosis and newly diagnosed osteoporosis
Bone 2010; 46: S31--IBMS Davos Workshops: Bone Biology & Therapeutics; MAR 14-19, 2010; Davos. Doi: 10.1016/j.bone.2010.01.064 [Poster]
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** Rainer, PP; Huber, MS; Edelmann, F; Stojakovic, T; Trantina-Yates, A; Trauner, M; Pieske, BM; Von Lewinski, D The primary bile-salt glycocholate induces arrhythmias in human atrial myocardium
CARDIOVASC RES. 2010; 87: S50-S50. [Poster]
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2009

Abstract (Journal)

** Rainer, PP; Huber, MS; Khafaga, M; Rossl, R; Gasser, R; Bisping, E; Machler, H; Pieske, B; von Lewinski, D Insulin-induced inotropy in human myocardium in diabetics and non-diabetics
WIEN KLIN WOCHENSCHR. 2009; 121(15-16):A35-A35. [Poster]
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2008

Abstract (Journal)

** Jost, C; Rainer, P; Eherer, A; Graninger, W; Weber, K Ulcerous esophagitis in osteoporosis: not only an undesirable side effect of bisphosphonates
WIEN KLIN WOCHENSCHR. 2008; 120(15-16):A43-A43. [Poster]
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