** = Publikationen gelistet in SCI/SSCI/Pubmed
** Meindl, C; Öhlinger, K; Zrim, V; Ober, J; Jeitler, R; Roblegg, E; Fröhlich, E
Skin Sensitization Potential of Sensitizers in the Presence of Metal Oxide Nanoparticles In Vitro.
Nanomaterials (Basel). 2024; 14(22): 1811
Doi: 10.3390/nano14221811
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** Radivojev, S; Kargl, L; Pinto, JT; Swedrowska, M; Malmlöf, M; Meindl, C; Forbes, B; Gerde, P; Paudel, A; Fröhlich, E
Integration of mucus and its impact within in vitro setups for inhaled drugs and formulations: Identifying the limits of simple vs. complex methodologies when studying drug dissolution and permeability.
Int J Pharm. 2024; 661: 124455
Doi: 10.1016/j.ijpharm.2024.124455
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** Corzo, C; Crvenjak, D; Sotirov, K; Urich, JA; Ohlinger, K; Meindl, C; Lochmann, D; Reyer, S; Frohlich, E; Zimmer, A; Salar-Behzadi, S
Lipid-based particle engineering via spray-drying for targeted delivery of antibiotics to the lung
INT J PHARMACEUT. 2023; 642: 123201
Doi: 10.1016/j.ijpharm.2023.123201
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** Meindl, C; Absenger-Novak, M; Jeitler, R; Roblegg, E; Frohlich, E
Assessment of Carbon Nanotubes on Barrier Function, Ciliary Beating Frequency and Cytokine Release in In Vitro Models of the Respiratory Tract
NANOMATERIALS-BASEL. 2023; 13(4): 682
Doi: 10.3390/nano13040682
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** Meindl, C; Öhlinger, K; Zrim, V; Steinkogler, T; Fröhlich, E
Screening for Effects of Inhaled Nanoparticles in Cell Culture Models for Prolonged Exposure.
Nanomaterials (Basel). 2021; 11(3):
Doi: 10.3390/nano11030606
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** Scheipl, S; Barnard, M; Lohberger, B; Zettl, R; Brcic, I; Liegl-Atzwanger, B; Rinner, B; Meindl, C; Fröhlich, E
Drug combination screening as a translational approach toward an improved drug therapy for chordoma.
Cell Oncol (Dordr). 2021; 44(6):1231-1242
Doi: 10.1007/s13402-021-00632-x
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** Tetyczka, C; Hartl, S; Jeitler, R; Absenger-Novak, M; Meindl, C; Frohlich, E; Riedl, S; Zweytick, D; Roblegg, E
Cytokine-Mediated Inflammation in the Oral Cavity and Its Effect on Lipid Nanocarriers
NANOMATERIALS-BASEL. 2021; 11(5): 1330
Doi: 10.3390/nano11051330
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** Corzo, C; Meindl, C; Lochmann, D; Reyer, S; Salar-Behzadi, S
Novel approach for overcoming the stability challenges of lipid-based excipients. Part 3: Application of polyglycerol esters of fatty acids for the next generation of solid lipid nanoparticles.
Eur J Pharm Biopharm. 2020; 152(3):44-55
Doi: 10.1016/j.ejpb.2020.04.027
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** Fröhlich, E; Öhlinger, K; Meindl, C; Corzo, C; Lochmann, D; Reyer, S; Salar-Behzadi, S
In vitro toxicity screening of polyglycerol esters of fatty acids as excipients for pulmonary formulations.
Toxicol Appl Pharmacol. 2019; 386: 114833-114833.
Doi: 10.1016/j.taap.2019.114833
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** Öhlinger, K; Absenger-Novak, M; Meindl, C; Ober, J; Fröhlich, E
Different Sensitivity of Macrophages to Phospholipidosis Induction by Amphiphilic Cationic Drugs.
Int J Mol Sci. 2020; 21(21):
Doi: 10.3390/ijms21218391
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** Panov, V; Minigalieva, I; Bushueva, T; Fröhlich, E; Meindl, C; Absenger-Novak, M; Shur, V; Shishkina, E; Gurvich, V; Privalova, L; Katsnelson, BA
Some Peculiarities in the Dose Dependence of Separate and Combined In Vitro Cardiotoxicity Effects Induced by CdS and PbS Nanoparticles With Special Attention to Hormesis Manifestations.
Dose Response. 2020; 18(1):1559325820914180-1559325820914180
Doi: 10.1177/1559325820914180
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** Salar-Behzadi, S; Corzo, C; Gomes Lopes, D; Meindl, C; Lochmann, D; Reyer, S
Novel approach for overcoming the stability challenges of lipid-based excipients. Part 2: Application of polyglycerol esters of fatty acids as hot melt coating excipients.
Eur J Pharm Biopharm. 2020; 148(3):107-117
Doi: 10.1016/j.ejpb.2020.01.009
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** Salar-Behzadi, S; Karrer, J; Demiri, V; Barrios, B; Corzo, C; Meindl, C; Lochmann, D; Reyer, S
Polyglycerol esters of fatty acids as safe and stable matrix forming tableting excipients: A structure-function analysis.
J DRUG DELIV SCI TEC. 2020; 60: 102019
Doi: 10.1016/j.jddst.2020.102019
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** Mischinger, J; Fröhlich, E; Mannweiler, S; Meindl, C; Absenger-Novak, M; Hutterer, GC; Seles, M; Augustin, H; Chromecki, TF; Jesche-Chromecki, J; Pummer, K; Zigeuner, R
Prognostic value of B7-H1, B7-H3 and the stage, size, grade and necrosis (SSIGN) score in metastatic clear cell renal cell carcinoma.
Cent European J Urol. 2019; 72(1): 23-31.
Doi: 10.5173/ceju.2018.1858
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** Öhlinger, K; Kolesnik, T; Meindl, C; Gallé, B; Absenger-Novak, M; Kolb-Lenz, D; Fröhlich, E
Air-liquid interface culture changes surface properties of A549 cells.
Toxicol In Vitro. 2019; 60(7): 369-382.
Doi: 10.1016/j.tiv.2019.06.014
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** Claudia, M; Kristin, Ö; Jennifer, O; Eva, R; Eleonore, F
Comparison of fluorescence-based methods to determine nanoparticle uptake by phagocytes and non-phagocytic cells in vitro.
Toxicology. 2017; 378(2):25-36
Doi: 10.1016/j.tox.2017.01.001
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** Minigalieva, I; Bushueva, T; Fröhlich, E; Meindl, C; Öhlinger, K; Panov, V; Varaksin, A; Shur, V; Shishkina, E; Gurviсh, V; Katsnelson, B
Are in vivo and in vitro assessments of comparative and combined toxicity of the same metallic nanoparticles compatible, or contradictory, or both? A juxtaposition of data obtained in respective experiments with NiO and Mn3O4 nanoparticles.
Food Chem Toxicol. 2017; 109(Pt 1):393-404
Doi: 10.1016/j.fct.2017.09.032
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** Salar-Behzadi, S; Wu, S; Mercuri, A; Meindl, C; Stranzinger, S; Fröhlich, E
Effect of the pulmonary deposition and in vitro permeability on the prediction of plasma levels of inhaled budesonide formulation.
Int J Pharm. 2017; 532(1):337-344
Doi: 10.1016/j.ijpharm.2017.08.124
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** Schaude, C; Fröhlich, E; Meindl, C; Attard, J; Binder, B; Mohr, GJ
The Development of Indicator Cotton Swabs for the Detection of pH in Wounds.
Sensors (Basel). 2017; 17(6):
Doi: 10.3390/s17061365
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** Schaude, C; Meindl, C; Fröhlich, E; Attard, J; Mohr, GJ
Developing a sensor layer for the optical detection of amines during food spoilage.
Talanta. 2017; 170(5-6):481-487
Doi: 10.1016/j.talanta.2017.04.029
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** Kornmueller, K; Lehofer, B; Meindl, C; Fröhlich, E; Leitinger, G; Amenitsch, H; Prassl, R
Peptides at the Interface: Self-Assembly of Amphiphilic Designer Peptides and Their Membrane Interaction Propensity.
Biomacromolecules. 2016; 17(11):3591-3601
Doi: 10.1021/acs.biomac.6b01089
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** Wu, S; Mercuri, A; Salar-Behzadi, S; Schiaretti, F; Zambelli, E; Brogin, G; Govoni, M; Meindl, C; Stranzinger, S; Mohr, S; Dzidic, N; Bresciani, M; Frohlich, E
INFLUENCE OF CALU-3 PERMEABILITY ON IN SILICO PHARMACOKINETIC PREDICTION OF INHALATION PRODUCTS
J AEROSOL MED PULM D. 2016; 29(3):A17-A18.-DDL26; Edinburgh.
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** Meindl, C; Kueznik, T; Bösch, M; Roblegg, E; Fröhlich, E
Intracellular calcium levels as screening tool for nanoparticle toxicity.
J Appl Toxicol. 2015; 35(10):1150-1159
Doi: 10.1002/jat.3160
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** Meindl, C; Stranzinger, S; Dzidic, N; Salar-Behzadi, S; Mohr, S; Zimmer, A; Fröhlich, E
Permeation of Therapeutic Drugs in Different Formulations across the Airway Epithelium In Vitro.
PLoS One. 2015; 10(8):e0135690-e0135690
Doi: 10.1371/journal.pone.0135690
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** Mrakovcic, M; Meindl, C; Leitinger, G; Roblegg, E; Fröhlich, E
Carboxylated short single-walled carbon nanotubes but not plain and multi-walled short carbon nanotubes show in vitro genotoxicity.
Toxicol Sci. 2015; 144(1):114-127
Doi: 10.1093/toxsci/kfu260
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** Fröhlich, E; Meindl, C; Wagner, K; Leitinger, G; Roblegg, E
Use of whole genome expression analysis in the toxicity screening of nanoparticles.
Toxicol Appl Pharmacol. 2014; 280(2):272-284
Doi: 10.1016/j.taap.2014.07.017
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** Mrakovcic, M; Meindl, C; Roblegg, E; Fröhlich, E
Reaction of monocytes to polystyrene and silica nanoparticles in short-term and long-term exposures.
Toxicol Res (Camb). 2014; 3(2):86-97
Doi: 10.1039/C3TX50112D
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** Prietl, B; Meindl, C; Roblegg, E; Pieber, TR; Lanzer, G; Fröhlich, E
Nano-sized and micro-sized polystyrene particles affect phagocyte function.
Cell Biol Toxicol. 2014; 30(1):1-16
Doi: 10.1007/s10565-013-9265-y
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** Schimpel, C; Teubl, B; Absenger, M; Meindl, C; Fröhlich, E; Leitinger, G; Zimmer, A; Roblegg, E
Development of an advanced intestinal in vitro triple culture permeability model to study transport of nanoparticles.
Mol Pharm. 2014; 11(3):808-818
Doi: 10.1021/mp400507g
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** Fröhlich, E; Bonstingl, G; Höfler, A; Meindl, C; Leitinger, G; Pieber, TR; Roblegg, E
Comparison of two in vitro systems to assess cellular effects of nanoparticles-containing aerosols.
Toxicol In Vitro. 2013; 27(1):409-417
Doi: 10.1016/j.tiv.2012.08.008
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** Fröhlich, E; Meindl, C; Höfler, A; Leitinger, G; Roblegg, E
Combination of small size and carboxyl functionalisation causes cytotoxicity of short carbon nanotubes.
Nanotoxicology. 2013; 7(7):1211-1224
Doi: 10.3109/17435390.2012.729274
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** Meindl, C; Absenger, M; Roblegg, E; Fröhlich, E
Suitability of cell-based label-free detection for cytotoxicity screening of carbon nanotubes.
Biomed Res Int. 2013; 2013(2):564804-564804
Doi: 10.1155/2013/564804
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** Teubl, BJ; Meindl, C; Eitzlmayr, A; Zimmer, A; Fröhlich, E; Roblegg, E
In-Vitro Permeability of Neutral Polystyrene Particles via Buccal Mucosa.
Small. 2013; 9(3):457-466
Doi: 10.1002/smll.201201789
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** Frohlich, E; Meindl, C; Roblegg, E; Ebner, B; Absenger, M; Pieber, TR;
Action of polystyrene nanoparticles of different sizes on lysosomal function and integrity.
Part Fibre Toxicol. 2012; 9(16):26-26
Doi: 10.1186/1743-8977-9-26
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** Fröhlich, E; Meindl, C; Roblegg, E; Griesbacher, A; Pieber, TR
Cytotoxity of nanoparticles is influenced by size, proliferation and embryonic origin of the cells used for testing.
Nanotoxicology. 2012; 6(4):424-439
Doi: 10.3109/17435390.2011.586478
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** Roblegg, E; Fröhlich, E; Meindl, C; Teubl, B; Zaversky, M; Zimmer, A
Evaluation of a physiological in vitro system to study the transport of nanoparticles through the buccal mucosa.
Nanotoxicology. 2012; 6(4):399-413
Doi: 10.3109/17435390.2011.580863
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** Luschnig-Schratl, P; Sturm, EM; Konya, V; Philipose, S; Marsche, G; Fröhlich, E; Samberger, C; Lang-Loidolt, D; Gattenlöhner, S; Lippe, IT; Peskar, BA; Schuligoi, R; Heinemann, A
EP4 receptor stimulation down-regulates human eosinophil function.
Cell Mol Life Sci. 2011; 68(21): 3573-3587.
Doi: 10.1007/s00018-011-0642-5
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** Frohlich, E; Kueznik, T; Samberger, C; Roblegg, E; Wrighton, C; Pieber, TR
Size-dependent effects of nanoparticles on the activity of cytochrome P450 isoenzymes.
TOXICOL APPL PHARMACOL. 2010; 242(3): 326-332.
Doi: 10.1016/j.taap.2009.11.002
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** Millotti, G; Samberger, C; Frohlich, E; Sakloetsakun, D; Bernkop-Schnurch, A
Chitosan-4-mercaptobenzoic acid: synthesis and characterization of a novel thiolated chitosan
J MATER CHEM. 2010; 20(12): 2432-2440.
Doi: 10.1039/b916528b
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** Frohlich, E; Samberger, C; Kueznik, T; Absenger, M; Roblegg, E; Zimmer, A; Pieber, TR
Cytotoxicity of nanoparticles independent from oxidative stress.
J TOXICOL SCI. 2009; 34(4): 363-375.
Doi: 10.2131/jts.34.363
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** Millotti, G; Samberger, C; Fröhlich, E; Bernkop-Schnürch, A
Chitosan-graft-6-mercaptonicotinic acid: synthesis, characterization, and biocompatibility.
Biomacromolecules. 2009; 10(11): 3023-3027.
Doi: 10.1021/bm9006248
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** Danzer, M; Jocic, M; Samberger, C; Painsipp, E; Bock, E; Pabst, MA; Crailsheim, K; Schicho, R; Lippe, IT; Holzer, P
Stomach-brain communication by vagal afferents in response to luminal acid backdiffusion, gastrin, and gastric acid secretion.
AMER J PHYSIOL-GASTROINTEST L. 2004; 286(3): G403-G411.
Doi: 10.1152/ajpgi.00308.2003
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** Danzer, M; Samberger, C; Schicho, R; Lippe, IT; Holzer, P
Immunocytochemical characterization of rat brainstem neurons with vagal afferent input from the stomach challenged by acid or ammonia.
Eur J Neurosci. 2004; 19(1):85-92
Doi: 10.1111/j.1460-9568.2004.03109.x
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** Holzer, P; Danzer, M; Schicho, R; Samberger, C; Painsipp, E; Lippe, IT
Vagal afferent input from the acid-challenged rat stomach to the brainstem: enhancement by interleukin-1beta.
NEUROSCIENCE. 2004; 129(2): 439-445.
Doi: 10.1016/j.neuroscience.2004.07.040
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** Holzer, P; Danzer, M; Samberger, C; Schicho, R; Lippe, IT
Three mechanisms of gut-brain communication induced by peripheral pentagastrin: Acid- and Cck1 receptor-mediated stimulation of vagal afferents and Cck2 receptor-mediated stimulation of area postrema neurons
GASTROENTEROLOGY. 2003; 124(4): A116-A116.
Doi: 10.1016/S0016-5085(03)80570-X
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