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Geigl Jochen Bernd |

** = Publications listed in SCI/SSCI/Pubmed

2023

Biographical-Item

** Verheyen, S; Heitzer, E; Geigl, J Obituary Prof. Dr. med. Michael Speicher
MED GENET-BERLIN. 2023; 35(4): 297-298. Doi: 10.1515/medgen-2023-2063
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2022

Full paper/article (Journal)

** Campos, DAS; Weihs, D; Rosenkranz, M; Langner, C; Geigl, JB; Tschmelitsch, J; Eberl, T Pre- and Postoperative Levels of Carcinoembryonic Antigen in Microsatellite Stable Versus Instable Colon Cancer: a Retrospective Analysis
J GASTROINTEST CANC. 2022; Doi: 10.1007/s12029-022-00841-z
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Abstract (Journal)

** Sieghartsleitner, E; Sunitsch, S; Rief, A; Regitnig, P; Geigl, J; Tamussino, K; Peintinger, F Somatic gene alterations in endometrial cancer and correlation with germline alterations
GEBURTSH FRAUENHEILK. 2022; 82(10):E162-E163. Doi: 10.1055/s-0042-1757051 [Poster]
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** Sieghartsleitner, E; Sunitsch, S; Rief, A; Regnitnig, P; Geigl, J; Tamussino, K; Peintinger, F Somatic Gene Changes in Endometrial Cancer and Correlation with Germline Changes
GEBURTSH FRAUENHEILK. 2022; 82(6):S48-S49. Doi: 10.1055/s-0042-1750237
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2021

Abstract (Journal)

** Sieghartsleitner, E; Sunitsch, S; Regitnig, P; Tamussino, K; Geigl, J; Peintinger, F Survey of somatic Gene Changes in Patients with Endometrial Cancer and Correlation with Germline Alterations
GEBURTSH FRAUENHEILK. 2021; 81(06):E28-E28. Doi: 10.1055/s-0041-1730510 [Poster]
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** Sieghartsleitner, EA; Sunitsch, S; Regitnig, P; Tamussino, K; Geigl, J; Peintinger, F Survey of somatic Gene Changes in Endometrial Cancer and Correlation with Changes in the Germline
GEBURTSH FRAUENHEILK. 2021; 81(04):E7-E7. Doi: 10.1055/s-0041-1726595 [Poster]
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2020

Full paper/article (Journal)

** Moser, T; Waldispuehl-Geigl, J; Belic, J; Weber, S; Zhou, Q; Hasenleithner, SO; Graf, R; Terzic, JA; Posch, F; Sill, H; Lax, S; Kashofer, K; Hoefler, G; Schoellnast, H; Heitzer, E; Geigl, JB; Bauernhofer, T; Speicher, MR On-treatment measurements of circulating tumor DNA during FOLFOX therapy in patients with colorectal cancer.
NPJ Precis Oncol. 2020; 4(1):30 Doi: 10.1038/s41698-020-00134-3 [OPEN ACCESS]
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** Perakis, SO; Weber, S; Zhou, Q; Graf, R; Hojas, S; Riedl, JM; Gerger, A; Dandachi, N; Balic, M; Hoefler, G; Schuuring, E; Groen, HJM; Geigl, JB; Heitzer, E; Speicher, MR Comparison of three commercial decision support platforms for matching of next-generation sequencing results with therapies in patients with cancer.
ESMO Open. 2020; 5(5):e000872 Doi: 10.1136/esmoopen-2020-000872 [OPEN ACCESS]
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** Zhou, Q; Perakis, SO; Ulz, P; Mohan, S; Riedl, JM; Talakic, E; Lax, S; Tötsch, M; Hoefler, G; Bauernhofer, T; Pichler, M; Gerger, A; Geigl, JB; Heitzer, E; Speicher, MR Cell-free DNA analysis reveals POLR1D-mediated resistance to bevacizumab in colorectal cancer.
Genome Med. 2020; 12(1):20 Doi: 10.1186/s13073-020-0719-6 [OPEN ACCESS]
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Correction

** Ulz, P; Perakis, S; Zhou, Q; Moser, T; Belic, J; Lazzeri, I; Wölfler, A; Zebisch, A; Gerger, A; Pristauz, G; Petru, E; White, B; Roberts, CES; John, JS; Schimek, MG; Geigl, JB; Bauernhofer, T; Sill, H; Bock, C; Heitzer, E; Speicher, MR Publisher Correction: Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection.
Nat Commun. 2020; 11(1): 1965-1965. Doi: 10.1038/s41467-020-15799-4 [OPEN ACCESS]
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Abstract (Journal)

** Moser, T; Waldispuehl-Geigl, J; Belic, J; Perakis, S; Weber, S; Zhou, Q; Sill, H; Lax, S; Kashofer, K; Hoefler, G; Schoellnast, H; Bauernhofer, T; Heitzer, E; Geigl, JB; Speicher, MR Early circulating tumor DNA dynamics as a real-time predictor of FOLFOX efficacy in advanced colorectal cancer patients
CANCER RES. 2020; 80(16): Doi: 10.1158/1538-7445.AM2020-4295 [Poster]
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** Perakis, SO; Weber, S; Graf, R; Zhou, Q; Riedl, JM; Dandachi, N; Balic, M; Gerger, A; Schuuring, E; Groen, HJ; Geigl, JB; Speicher, MR; Heitzer, E Identification of actionable targets in advanced cancer patients from circulating tumor DNA using clinical decision support platforms
CANCER RES. 2020; 80(16):-AACR Annual Meeting; JUN 22-24, 2020; ELECTR NETWORK. Doi: 10.1158/1538-7445.AM2020-1315 [Poster]
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** Trapp, E; Kolovetsiou-Kreiner, V; Reisinger, J; Bramreiter, V; Speicher, M; Geigl, J; Petru, E; Tamussino, K; Pristauz, G Multiple Gene analysis in Breast and Ovarian Cancer Patients.
GEBURTSH FRAUENHEILK. Kongressabstracts zur Wissenschaftlichen Tagung der Arbeitsgemeinschaft für gynäkologische Onkologie (AGO) der Österreichischen Gesellschaft für Gynäkologie und Geburtshilfe (OEGGG). 2020; 80(4):436-436.-Tagung der Arbeitsgemeinschaft für gynäkologische Onkologie (AGO) der Österreichischen Gesellschaft für Gynäkologie und Geburtshilfe (OEGGG); MAI 8-11, 2020; Salzburg, AUSTRIA. [Poster]
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** Trapp, EK; Speicher, M; Geigl, JB; Kolovetsiou-Kreiner, V; Reisinger, J; Haas, J; Petru, E; Tamussino, K; Pristauz, G Multigene panel analysis in breast and ovarian cancer.
CANCER RES. 2020; 80(4):-San Antonio Breast Cancer Symposium; DEC 10-14, 2019; San Antonio, TX. Doi: 10.1158/1538-7445.SABCS19-P5-03-09 [Poster]
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2019

Full paper/article (Journal)

** Ulz, P; Perakis, S; Zhou, Q; Moser, T; Belic, J; Lazzeri, I; Wölfler, A; Zebisch, A; Gerger, A; Pristauz, G; Petru, E; White, B; Roberts, CES; John, JS; Schimek, MG; Geigl, JB; Bauernhofer, T; Sill, H; Bock, C; Heitzer, E; Speicher, MR Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection.
Nat Commun. 2019; 10(1): 4666-4666. Doi: 10.1038/s41467-019-12714-4 [OPEN ACCESS]
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Abstract (Journal)

** Perakis, SO; Ulz, P; Riedl, JM; Scheipner, L; Kashofer, K; Hoefler, G; Geigl, JB; Speicher, MR; Heitzer, E; Gerger, A Molecular-biological tumor profiling for drug treatment selection in patients with advanced and refractory carcinoma: A prospective, two-stage Phase II individualized cancer treatment study
CANCER RES. 2019; 79(13):-Annual Meeting of the American-Association-for-Cancer-Research (AACR); MAR 29-APR 03, 2019; Atlanta, GA. Doi: 10.1158/1538-7445.AM2019-CT130 [Poster]
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2018

Full paper/article (Journal)

** Belic, J; Graf, R; Bauernhofer, T; Cherkas, Y; Ulz, P; Waldispuehl-Geigl, J; Perakis, S; Gormley, M; Patel, J; Li, W; Geigl, JB; Smirnov, D; Heitzer, E; Gross, M; Speicher, MR Genomic alterations in plasma DNA from patients with metastasized prostate cancer receiving abiraterone or enzalutamide.
Int J Cancer. 2018; 143(5): 1236-1248. Doi: 10.1002/ijc.31397 [OPEN ACCESS]
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Abstract (Journal)

** Belic, J; Graf, R; Bauernhofer, T; Cherkas, Y; Peter, U; Waldispuehl-Geigl, J; Perakis, S; Gormley, M; Patel, J; Li, WM; Geigl, JB; Smirnov, D; Heitzer, E; Gross, M; Speicher, MR Analysis of circulating tumor DNA reveals genomic alterations in metastatic prostate cancer patients treated with abiraterone acetate plus prednisone or enzalutamide
CANCER RES. 2018; 78(13):-Annual Meeting of the American-Association-for-Cancer-Research (AACR); APR 14-18, 2018; Chicago, IL. Doi: 10.1158/1538-7445.AM2018-2959 [Oral Communication]
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2017

Short report/Letter

** Moser, T; Ulz, P; Zhou, Q; Perakis, S; Geigl, JB; Speicher, MR; Heitzer, E Single-Stranded DNA Library Preparation Does Not Preferentially Enrich Circulating Tumor DNA.
Clin Chem. 2017; 63(10):1656-1659 Doi: 10.1373/clinchem.2017.277988 [OPEN ACCESS]
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Review

** Heitzer, E; Perakis, S; Geigl, JB; Speicher, MR The potential of liquid biopsies for the early detection of cancer.
NPJ Precis Oncol. 2017; 1(1):36-36 Doi: 10.1038/s41698-017-0039-5 [OPEN ACCESS]
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** Ulz, P; Heitzer, E; Geigl, JB; Speicher, MR Patient monitoring through liquid biopsies using circulating tumor DNA.
Int J Cancer. 2017; 141(5):887-896 Doi: 10.1002/ijc.30759 [OPEN ACCESS]
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Case Report

** Smolle, MA; Heitzer, E; Geigl, JB; Al, Kaissi, A; Liegl-Atzwanger, B; Seidel, MG; Holzer, LA; Leithner, A A novel mutation in ATRX associated with intellectual disability, syndromic features, and osteosarcoma.
Pediatr Blood Cancer. 2017; 64(10): Doi: 10.1002/pbc.26522 (- Case Report)
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Abstract (Journal)

** Graier, T; Auer, M; Heitzer, E; Ulz, P; Perakis, S; Speicher, MR; Geigl, JB Rapid single-cell copy-number aberration analysis using high- throughput sequencing.
EUR J CANCER. 2017; 72: S24-S24.-ECCO European Cancer Congress; JAN 27-30, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0959-8049(17)30159-4 [Poster]
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2016

Full paper/article (Journal)

** Belic, J; Koch, M; Ulz, P; Auer, M; Gerhalter, T; Mohan, S; Fischereder, K; Petru, E; Bauernhofer, T; Geigl, JB; Speicher, MR; Heitzer, E mFast-SeqS as a Monitoring and Pre-screening Tool for Tumor-Specific Aneuploidy in Plasma DNA.
Adv Exp Med Biol. 2016; 924:147-155 Doi: 10.1007/978-3-319-42044-8_28
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** Heitzer, E; Ulz, P; Geigl, JB Circulating tumor DNA as liquid biopsy for cancer
BIOCHIM CLIN. 2016; 40(3): 270-281. Doi: 10.19186/BC_2016.016
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** Liegl-Atzwanger, B; Heitzer, E; Flicker, K; Müller, S; Ulz, P; Saglam, O; Tavassoli, F; Devouassoux-Shisheboran, M; Geigl, J; Moinfar, F Exploring chromosomal abnormalities and genetic changes in uterine smooth muscle tumors.
Mod Pathol. 2016; 29(10):1262-1277 Doi: 10.1038/modpathol.2016.107 [OPEN ACCESS]
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** Ulz, P; Belic, J; Graf, R; Auer, M; Lafer, I; Fischereder, K; Webersinke, G; Pummer, K; Augustin, H; Pichler, M; Hoefler, G; Bauernhofer, T; Geigl, JB; Heitzer, E; Speicher, MR Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer.
Nat Commun. 2016; 7(15):12008-12008 Doi: 10.1038/ncomms12008 [OPEN ACCESS]
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** Ulz, P; Thallinger, GG; Auer, M; Graf, R; Kashofer, K; Jahn, SW; Abete, L; Pristauz, G; Petru, E; Geigl, JB; Heitzer, E; Speicher, MR Inferring expressed genes by whole-genome sequencing of plasma DNA.
Nat Genet. 2016; 48(10):1273-1278 Doi: 10.1038/ng.3648
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** Zebisch, A; Lal, R; Müller, M; Lind, K; Kashofer, K; Girschikofsky, M; Fuchs, D; Wölfler, A; Geigl, JB; Sill, H Acute myeloid leukemia with TP53 germ line mutations.
Blood. 2016; 128(18): 2270-2272. Doi: 10.1182/blood-2016-08-732610 [OPEN ACCESS]
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Review

** Heitzer, E; Ulz, P; Geigl, JB; Speicher, MR Non-invasive detection of genome-wide somatic copy number alterations by liquid biopsies.
Mol Oncol. 2016; 10(3):494-502 Doi: 10.1016/j.molonc.2015.12.004 [OPEN ACCESS]
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** Ulz, P; Geigl, JB; Speicher, MR; Heitzer, E Latest technological developments in the analysis of circulating tumor DNA
MED GENET-BERLIN. 2016; 28(2): 234-244. Doi: 10.1007/s11825-016-0089-z [OPEN ACCESS]
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Abstract (Journal)

** Belic, J; Heitzer, E; Ulz, P; Auer, M; Fischereder, K; Bauernhofer, T; Geigl, JB; Speicher, MR Analysis of ctDNA using the mFastSeqS and plasma-Seq methods for screening and therapy monitoring in prostate cancer patients
CLIN CANCER RES. 2016; 22: -Meeting of the American-Association-for-Cancer-Research (AACR) Precision Medicine Series - Integrating Clinical Genomics and Cancer Therapy; JUN 13-16, 2015; Salt Lake, UT. Doi: 10.1158/1557-3265.PMSCLINGEN15-PR05 [Oral Communication]
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2015

Full paper/article (Journal)

** Belic, J; Koch, M; Ulz, P; Auer, M; Gerhalter, T; Mohan, S; Fischereder, K; Petru, E; Bauernhofer, T; Geigl, JB; Speicher, MR; Heitzer, E Rapid Identification of Plasma DNA Samples with Increased ctDNA Levels by a Modified FAST-SeqS Approach.
Clin Chem. 2015; 61(6):838-849 Doi: 10.1373/clinchem.2014.234286 [OPEN ACCESS]
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Review

** Heitzer, E; Ulz, P; Geigl, JB Circulating tumor DNA as a liquid biopsy for cancer.
Clin Chem. 2015; 61(1):112-123 Doi: 10.1373/clinchem.2014.222679 [OPEN ACCESS]
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Abstract (Journal)

** Heitzer, E; Ulz, P; Auer, M; Belic, J; Sumitra, M; Lax, S; Hoefler, G; Augustin, H; Edgar, P; Bauernhofer, T; Geigl, J; Speicher, M Clinical utility of circulating tumor DNA in human cancers: A report of more than 300 plama-Seqs
EUR J CANCER. 2015; 51: S33-S33.-European Cancer Congress; Sep 25-29, 2015; Vienna, AUSTRIA. Doi: 10.1016/S0959-8049(16)30108-3 [Poster]
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** Speicher, MR; Heitzer, E; Ulz, P; Geigl, JB; Monitoring tumor evolution by whole-genome plasma sequencing
CANCER RES. 2015; 75: -106th Annual Meeting of the American-Association-for-Cancer-Research (AACR); APR 18-22, 2015; Philadelphia, PA. Doi: 10.1158/1538-7445.AM2015-SY37-02 [Oral Communication]
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2014

Full paper/article (Journal)

** Heidary, M; Auer, M; Ulz, P; Heitzer, E; Petru, E; Gasch, C; Riethdorf, S; Mauermann, O; Lafer, I; Pristauz, G; Lax, S; Pantel, K; Geigl, JB; Speicher, MR The dynamic range of circulating tumor DNA in metastatic breast cancer.
Breast Cancer Res. 2014; 16(4):421-421 Doi: 10.1186/s13058-014-0421-y [OPEN ACCESS]
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** Mohan, S; Heitzer, E; Ulz, P; Lafer, I; Lax, S; Auer, M; Pichler, M; Gerger, A; Eisner, F; Hoefler, G; Bauernhofer, T; Geigl, JB; Speicher, MR Changes in colorectal carcinoma genomes under anti-EGFR therapy identified by whole-genome plasma DNA sequencing.
PLoS Genet. 2014; 10(3):e1004271-e1004271 Doi: 10.1371/journal.pgen.1004271 [OPEN ACCESS]
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** Müller, C; Holtschmidt, J; Auer, M; Heitzer, E; Lamszus, K; Schulte, A; Matschke, J; Langer-Freitag, S; Gasch, C; Stoupiec, M; Mauermann, O; Peine, S; Glatzel, M; Speicher, MR; Geigl, JB; Westphal, M; Pantel, K; Riethdorf, S Hematogenous dissemination of glioblastoma multiforme.
Sci Transl Med. 2014; 6(247):247ra101-247ra101 Doi: 10.1126/scitranslmed.3009095 [OPEN ACCESS]
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** Schulz, E; Klampfl, P; Holzapfel, S; Janecke, AR; Ulz, P; Renner, W; Kashofer, K; Nojima, S; Leitner, A; Zebisch, A; Wölfler, A; Hofer, S; Gerger, A; Lax, S; Beham-Schmid, C; Steinke, V; Heitzer, E; Geigl, JB; Windpassinger, C; Hoefler, G; Speicher, MR; Boland, CR; Kumanogoh, A; Sill, H Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.
Nat Commun. 2014; 5(10):5191-5191 Doi: 10.1038/ncomms6191 [OPEN ACCESS]
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Abstract (Journal)

** Auer, M; Heitzer, E; Ulz, P; Pristauz, G; Petru, E; Jahn, S; Speicher, MR; Geigl, JB; Whole-genome sequencing of plasma DNA reveals frequently occurring copy number changes in patients with metastatic breast cancer.
EUR J CANCER. 2014; 50: S153-S153.-EACR; München. Doi: 10.1016/S0959-8049(14)50562-X [Oral Communication]
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** Heitzer, E; Mohan, S; Ulz, P; Lafer, I; Auer, M; Lax, S; Hoefler, G; Bauernhofer, T; Geigl, JB; Speicher, MR; Changes in colorectal carcinoma genomes under anti-EGFR therapy identified by whole-genome plasma DNA sequencing.
EUR J CANCER. 2014; 50: S96-S96.-EACR 2014; München. Doi: 10.1016/S0959-8049(14)50357-7 [Poster]
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** Schulz, E; Klampfl, P; Holzapfel, S; Janecke, AR; Ulz, P; Renner, W; Kashofer, K; Najima, S; Leitner, A; Zebisch, A; Wölfler, A; Hofer, S; Gerger, A; Lax, S; Beham-Schmid, C; Steinke, V; Geigl, JB; Höfler, G; Speicher, MR; Boland, CR; Kumanogoh, A; Sill, H Germline variants in the semaphorin SEMA4A confer susceptibility to familial colorectal cancer type X
Oncol Res Treat. 2014; 37(S5):105-105.-Annual Meeting of the German, Austrian and Swiss Associations of Hematology and Medical Oncology; OCT 10-14, 2014; Hamburg, GERMANY. (ISBN: 978-3-318-02811-9 ) [Oral Communication]
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2013

Full paper/article (Journal)

** Balic, M; Schwarzenbacher, D; Stanzer, S; Heitzer, E; Auer, M; Geigl, JB; Cote, RJ; Datar, RH; Dandachi, N Genetic and epigenetic analysis of putative breast cancer stem cell models.
BMC Cancer. 2013; 13(7):358-358 Doi: 10.1186/1471-2407-13-358 [OPEN ACCESS]
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** El-Heliebi, A; Kroneis, T; Zöhrer, E; Haybaeck, J; Fischereder, K; Kampel-Kettner, K; Zigeuner, R; Pock, H; Riedl, R; Stauber, R; Geigl, JB; Huppertz, B; Sedlmayr, P; Lackner, C Are morphological criteria sufficient for the identification of circulating tumor cells in renal cancer?
J Transl Med. 2013; 11(10):214-214 Doi: 10.1186/1479-5876-11-214 [OPEN ACCESS]
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** Fruhmann, J; Geigl, JB; Konstantiniuk, P; Cohnert, TU Paraganglioma of the Carotid Body: Treatment Strategy and SDH-gene Mutations.
Eur J Vasc Endovasc Surg. 2013; 45(5):431-436 Doi: 10.1016/j.ejvs.2013.01.018 [OPEN ACCESS]
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** Heitzer, E; Auer, M; Gasch, C; Pichler, M; Ulz, P; Hoffmann, EM; Lax, S; Waldispuehl-Geigl, J; Mauermann, O; Lackner, C; Höfler, G; Eisner, F; Sill, H; Samonigg, H; Pantel, K; Riethdorf, S; Bauernhofer, T; Geigl, JB; Speicher, MR Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing.
Cancer Res. 2013; 73(10):2965-2975 Doi: 10.1158/0008-5472.CAN-12-4140 [OPEN ACCESS]
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** Heitzer, E; Auer, M; Hoffmann, EM; Pichler, M; Gasch, C; Ulz, P; Lax, S; Waldispuehl-Geigl, J; Mauermann, O; Mohan, S; Pristauz, G; Lackner, C; Höfler, G; Eisner, F; Petru, E; Sill, H; Samonigg, H; Pantel, K; Riethdorf, S; Bauernhofer, T; Geigl, JB; Speicher, MR Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer.
Int J Cancer. 2013; 133(2):346-356 Doi: 10.1002/ijc.28030 [OPEN ACCESS]
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** Heitzer, E; Lax, S; Lafer, I; Müller, SM; Pristauz, G; Ulz, P; Jahn, S; Högenauer, C; Petru, E; Speicher, MR; Geigl, JB Multiplex genetic cancer testing identifies pathogenic mutations in TP53 and CDH1 in a patient with bilateral breast and endometrial adenocarcinoma.
BMC Med Genet. 2013; 14(1):129-129 Doi: 10.1186/1471-2350-14-129 (- Case Report) [OPEN ACCESS]
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** Heitzer, E; Ulz, P; Belic, J; Gutschi, S; Quehenberger, F; Fischereder, K; Benezeder, T; Auer, M; Pischler, C; Mannweiler, S; Pichler, M; Eisner, F; Haeusler, M; Riethdorf, S; Pantel, K; Samonigg, H; Hoefler, G; Augustin, H; Geigl, JB; Speicher, MR Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing.
Genome Med. 2013; 5(4):30-30 Doi: 10.1186/gm434 [OPEN ACCESS]
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Review

** Heitzer, E; Auer, M; Ulz, P; Geigl, JB; Speicher, MR Circulating tumor cells and DNA as liquid biopsies.
Genome Med. 2013; 5(8):73-73 Doi: 10.1186/gm477 [OPEN ACCESS]
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Editorial

** Auer, M; Heitzer, E; Ulz, P; Geigl, JB; Speicher, MR Single circulating tumor cell sequencing for monitoring.
Oncotarget. 2013; 4(6):812-813 Doi: 10.18632/oncotarget.1026 [OPEN ACCESS]
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Abstract (Journal)

** Auer, M; Heitzer, E; Ulz, P; Pristauz, G; Petru, E; Jahn, S; Lafer, I; Pantel, K; Speicher, MR; Geigl, JB Complex tumor genomes inferred from plasma DNA of patients with metastatic breast cancer by whole-genome sequencing
EUR J CANCER. 2013; 49: S399-S399.-17th ECCO / 38th ESMO / 32nd ESTRO European Cancer Congress on Reinforcing Multidisciplinarity; SEP 27-OCT 01, 2013; Amsterdam, NETHERLANDS. [Oral Communication]
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** Heitzer, E; Ulz, P; Belic, J; Gutschi, S; Quehenberger, F; Auer, M; Augustin, H; Hoefler, G; Geigl, JB; Speicher, MR Tumor associated copy number changes identified by whole-genome sequencing in the circulation of patients with prostate cancer
EUR J CANCER. 2013; 49: S98-S98.-17th ECCO / 38th ESMO / 32nd ESTRO European Cancer Congress on Reinforcing Multidisciplinarity; SEP 27-OCT 01, 2013; Amsterdam, NETHERLANDS. [Oral Communication]
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2012

Full paper/article (Journal)

** Frings, A; Geigl, JB; Liegl-Atzwanger, B; Leithner, A Familial aggregation of urinary tract and bone tumors: searching for a syndrome.
Case Rep Med. 2012; 2012(2):107894-107894 Doi: 10.1155/2012/107894 [OPEN ACCESS]
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** Mathiesen, RR; Fjelldal, R; Liestl, K; Due, EU; Geigl, JB; Riethdorf, S; Borgen, E; Rye, IH; Schneider, IJ; Obenauf, AC; Mauermann, O; Nilsen, G; Christian Lingjaerde, O; Brresen-Dale, AL; Pantel, K; Speicher, MR; Naume, B; Baumbusch, LO High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer.
Int J Cancer. 2012; 131(4):E405-E415 Doi: 10.1002/ijc.26444 [OPEN ACCESS]
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** Schulz, E; Valentin, A; Ulz, P; Beham-Schmid, C; Lind, K; Rupp, V; Lackner, H; Wölfler, A; Zebisch, A; Olipitz, W; Geigl, J; Berghold, A; Speicher, MR; Sill, H Germline mutations in the DNA damage response genes BRCA1, BRCA2, BARD1 and TP53 in patients with therapy related myeloid neoplasms.
J Med Genet. 2012; 49(7):422-428 Doi: 10.1136/jmedgenet-2011-100674
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** Wiesner, T; Fried, I; Ulz, P; Stacher, E; Popper, H; Murali, R; Kutzner, H; Lax, S; Smolle-Jüttner, F; Geigl, JB; Speicher, MR Toward an improved definition of the tumor spectrum associated with BAP1 germline mutations.
J Clin Oncol. 2012; 30(32):e337-e340 Doi: 10.1200/JCO.2011.41.2965 (- Case Report) [OPEN ACCESS]
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Abstract (Journal)

** Schulz, E; Valentin, A; Ulz, P; Beham-Schmid, C; Lind, K; Rupp, V; Lackner, H; Wolfler, A; Zebisch, A; Olipitz, W; Geigl, JB; Berghold, A; Speicher, MR; Sill, H Germ-line mutations in cancer predisposing genes BRCA1, BRCA2, BARD1 and TP53 in patients with therapy-related myeloid neoplasms.
ONKOLOGIE. Onkologie. 2012; 35: 117-117.-Annual Meeting of the German, Austrian and Swiss Associations of Hematology and Medical Oncology; OCT 19-23, 2012; Stuttgart, GERMANY. [Poster]
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2011

Full paper/article (Journal)

** Aleksic, K; Lackner, C; Geigl, JB; Schwarz, M; Auer, M; Ulz, P; Fischer, M; Trajanoski, Z; Otte, M; Speicher, MR Evolution of genomic instability in diethylnitrosamine-induced hepatocarcinogenesis in mice.
Hepatology. 2011; 53(3):895-904 Doi: 10.1002/hep.24133 [OPEN ACCESS]
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** Kroneis, T; Geigl, JB; El-Heliebi, A; Auer, M; Ulz, P; Schwarzbraun, T; Dohr, G; Sedlmayr, P Combined molecular genetic and cytogenetic analysis from single cells after isothermal whole-genome amplification.
Clin Chem. 2011; 57(7):1032-1041 Doi: 10.1373/clinchem.2011.162131 [OPEN ACCESS]
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Short report/Letter

** Jahn, SW; Winter, G; Stacher, E; Halbwedl, I; Gattenlöhner, S; Stockinger, R; Spreitzer, S; Waldispuehl-Geigl, J; Geigl, JB; Offner, F; Hoefler, G Multiple intratumoral KRAS mutations can clonally segregate to different lymph node metastases in colon cancer.
Histopathology. 2011; 59(2): 342-345. Doi: 10.1111/j.1365-2559.2011.03902.x (- Case Report)
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Review

** Geigl, JB; Speicher, MR Nichtinvasive molekulargenetische Methoden in der pränatalen Diagnostik.
Medizinische Genetik. 2011; 23(4): 485-489. Doi: 10.1007/s11825-011-0304-x
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Abstract (Journal)

** Hofmann, G; Geigl, JB; Kastner, N; Leithner, A; Koppany, B; Samonigg, H; Gruber, G Genetic differences in preoperative specimen of osteosarcoma and their impact on response to neoadjuvant chemotherapy
ONKOLOGIE. 2011; 34: 251-252.-Gemeinsame Jahrestagung 2011 der DGHO, ÖGHO, SGMO und SGH+SSH; SEP 30-OCT 4, 2011; Basel, SCHWEIZ. [Poster]
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2010

Full paper/article (Journal)

** Geigl, JB; Heitzer, E; Speicher, MR Predictive five prognostic genetic biomarkers.
WIEN KLIN WOCHENSCHR. 2010; 122 Suppl 2(8): 49-70.
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** Obenauf, AC; Schwarzbraun, T; Auer, M; Hoffmann, EM; Waldispuehl-Geigl, J; Ulz, P; Günther, B; Duba, HC; Speicher, MR; Geigl, JB Mapping of balanced chromosome translocation breakpoints to the basepair level from microdissected chromosomes.
J Cell Mol Med. 2010; 14(8):2078-2084 Doi: 10.1111/j.1582-4934.2010.01116.x (- Case Report) [OPEN ACCESS]
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** Pabst, MA; Letofsky-Papst, I; Moser, M; Spindler, K; Bock, E; Wilhelm, P; Dorfer, L; Geigl, JB; Auer, M; Speicher, MR; Hofer, F Different staining substances were used in decorative and therapeutic tattoos in a 1000-year-old Peruvian mummy
J ARCHAEOL SCI. 2010; 37(12): 3256-3262. Doi: 10.1016/j.jas.2010.07.026
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** Pristauz, G; Petru, E; Stacher, E; Geigl, JB; Schwarzbraun, T; Tsybrovskyy, O; Winter, R; Moinfar, F Androgen receptor expression in breast cancer patients tested for BRCA1 and BRCA2 mutations.
Histopathology. 2010; 57(6):877-884 Doi: 10.1111/j.1365-2559.2010.03724.x
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** Speicher, MR; Geigl, JB; Tomlinson, IP Effect of genome-wide association studies, direct-to-consumer genetic testing, and high-speed sequencing technologies on predictive genetic counselling for cancer risk.
Lancet Oncol. 2010; 11(9): 890-898. Doi: 10.1016/S1470-2045(09)70359-6
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** Wolf, EM; Geigl, JB; Svrcek, M; Vieth, M; Langner, C Hereditary gastric cancer].
Pathologe. 2010; 31(6):423-429 Doi: 10.1007/s00292-010-1353-7
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Review

** Pristauz, G; Geigl, JB; Petru, E BRCA1- and BRCA2 mutations: Clinical management of patients with hereditary breast and ovarian cancer.
Wien Med Wochenschr. 2010; 160(7-8): 158-162. Doi: 10.1007/s10354-010-0772-7
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Abstract (Journal)

** Mathiesen, RR; Fjelldal, R; Due, EU; Geigl, JB; Riethdorf, S; Borresen-Dale, AL; Pantel, K; Speicher, MR; Baumbusch, LO; Naume, B Genomic profiles of single tumour cells in metastatic breast cancer patients
EJC SUPPL. 2010; 8(5): 367 Doi: 10.1016/S1359-6349(10)71168-X
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** Pristauz, G; Petru, E; Stacher, E; Geigl, J; Speicher, M; Winter, R; Moinfar, F Androgen receptor expression in patients with BRCA1/2-positive and BRCA1/2-negative breast cancer
GYNECOL ONCOL. 2010; 116(3):62- [Keynote lecture]
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** Pristauz, G; Petru, E; Stacher, E; Geigl, JB; Schwarzbraun, T; Tsybrovskyy, O; Winter, R; Moinfar, F Expression of Androgen receptors in breast cancer patients after BRCA1 and BRCA 2 0-mutation test
GEBURTSH FRAUENHEILK. 2010; 70(3):244-244.-Jahrestagung der OEGGG; JUN 2-6, 2010; Zell am See, AUSTRIA. [Poster]
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** Pristauz, G; Petru, E; Stacher, E; Geigl, JB; Schwarzbraun, T; Tsybrovvskyy, O; Winter, R; Moinfar, F Expression of Androgen receptors in Breast carcinomas of patients for BRCA1 and BRCA2 Mutation Testing.
GEBURTSH FRAUENHEILK. 2010; 70(5):P54- [Keynote lecture]
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2009

Full paper/article (Journal)

** Geigl, JB; Obenauf, AC; Waldispuehl-Geigl, J; Hoffmann, EM; Auer, M; Hörmann, M; Fischer, M; Trajanoski, Z; Schenk, MA; Baumbusch, LO; Speicher, MR Identification of small gains and losses in single cells after whole genome amplification on tiling oligo arrays.
Nucleic Acids Res. 2009; 37(15): e105-e105. Doi: 10.1093/nar/gkp526 [OPEN ACCESS]
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Short report/Letter

** Harbaum, L; Geigl, JB; Volkholz, H; Schwarzbraun, T; Oschmautz, H; Vieth, M; Langner, C Sporadic gastric Peutz-Jeghers polyp with intraepithelial neoplasia
APMIS. 2009; 117(12): 941-943. Doi: 10.1111/j.1600-0463.2009.02549.x (- Case Report)
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** Wiesner, T; Obenauf, AC; Geigl, JB; Vallant, EM; Speicher, MR; Fink-Puches, R; Kerl, H; Cerroni, L 9p21 deletion in primary cutaneous large B-cell lymphoma, leg type, may escape detection by standard FISH assays.
J Invest Dermatol. 2009; 129(1): 238-240. Doi: 10.1038/jid.2008.224 (- Case Report) [OPEN ACCESS]
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Abstract (Journal)

** Baumbusch, LO; Geigl, JB; Riethdorf, S; Schneider, IJ; Mathiesen, RMR; Fjelldal, R; Borresen-Dale, AL; Pantel, K; Speicher, MR; Naume, B Molecular signatures of disseminated tumour cells in metastatic breast cancer patients
EJC SUPPL. 2009; 7(2):113-114.-34th ESMO Multidisciplinary Congress BERLIN; 20–24 SEPTEMBER 2009 ; Berlin. Doi: 10.1016/S1359-6349(09)70389-1 [Oral Communication]
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2008

Full paper/article (Journal)

** Geigl, J; Speicher, M New methods of single-cell analysis in research and diagnostics
MED GENET. 2008; 20(4): 407-415. Doi: 10.1007/s11825-008-0138-3
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** Hüsemann, Y; Geigl, JB; Schubert, F; Musiani, P; Meyer, M; Burghart, E; Forni, G; Eils, R; Fehm, T; Riethmüller, G; Klein, CA Systemic spread is an early step in breast cancer.
Cancer Cell. 2008; 13(1):58-68 Doi: 10.1016/j.ccr.2007.12.003 [OPEN ACCESS]
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Review

** Geigl, JB; Obenauf, AC; Schwarzbraun, T; Speicher, MR Defining 'chromosomal instability'.
Trends Genet. 2008; 24(2): 64-69. Doi: 10.1016/j.tig.2007.11.006
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2007

Full paper/article (Journal)

** Fiegler, H; Geigl, JB; Langer, S; Rigler, D; Porter, K; Unger, K; Carter, NP; Speicher, MR High resolution array-CGH analysis of single cells.
Nucleic Acids Res. 2007; 35(3): e15-e15. Doi: 10.1093/nar/gkl1030 [OPEN ACCESS]
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** Geigl, JB; Speicher, MR Single-cell isolation from cell suspensions and whole genome amplification from single cells to provide templates for CGH analysis.
Nat Protoc. 2007; 2(12): 3173-3184. Doi: 10.1038/nprot.2007.476
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** Miething, C; Grundler, R; Mugler, C; Brero, S; Hoepfl, J; Geigl, J; Speicher, MR; Ottmann, O; Peschel, C; Duyster, J Retroviral insertional mutagenesis identifies RUNX genes involved in chronic myeloid leukemia disease persistence under imatinib treatment.
Proc Natl Acad Sci U S A. 2007; 104(11): 4594-4599. Doi: 10.1073/pnas.0604716104 [OPEN ACCESS]
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** Uhrig, S; Geigl, JB; Speicher, MR Genetic counseling in multiple pregnancies
Gynakol Geburtshilfliche Rundsch. 2007; 47(1): 9-13. Doi: 10.1159/000098120
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Short report/Letter

** Uhrig, S; Schlembach, D; Waldispuehl-Geigl, J; Schaffer, W; Geigl, J; Klopocki, E; Mundlos, S; Speicher, MR Impact of array comparative genomic hybridization-derived information on genetic counseling demonstrated by prenatal diagnosis of the TAR (thrombocytopenia-absent-radius) syndrome-associated microdeletion 1q21.1.
Am J Hum Genet. 2007; 81(4): 866-868. Doi: 10.1086/521338 [OPEN ACCESS]
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2006

Full paper/article (Journal)

** Geigl, JB; Uhrig, S; Speicher, MR Multiplex-fluorescence in situ hybridization for chromosome karyotyping.
Nat Protoc. 2006; 1(3): 1172-1184. Doi: 10.1038/nprot.2006.160
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** Langer, S; Geigl, JB; Wagenstaller, J; Lederer, G; Hempel, M; Daumer-Haas, C; Leifheit, HJ; Speicher, MR Delineation of a 2q deletion in a girl with dysmorphic features and epilepsy.
Am J Med Genet A. 2006; 140(7):764-768 Doi: 10.1002/ajmg.a.31141 (- Case Report)
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2005

Full paper/article (Journal)

** Langer, S; Geigl, JB; Ehnle, S; Gangnus, R; Speicher, MR Live cell catapulting and recultivation does not change the karyotype of HCT116 tumor cells.
Cancer Genet Cytogenet. 2005; 161(2):174-177 Doi: 10.1016/j.cancergencyto.2005.01.013
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** Langer, S; Geigl, JB; Gangnus, R; Speicher, MR Sequential application of interphase-FISH and CGH to single cells.
Lab Invest. 2005; 85(4):582-592 Doi: 10.1038/labinvest.3700249 [OPEN ACCESS]
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2004

Full paper/article (Journal)

** Geigl, JB; Langer, S; Barwisch, S; Pfleghaar, K; Lederer, G; Speicher, MR Analysis of gene expression patterns and chromosomal changes associated with aging.
Cancer Res. 2004; 64(23):8550-8557 Doi: 10.1158/0008-5472.CAN-04-2151 [OPEN ACCESS]
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** Thalhammer, S; Langer, S; Speicher, MR; Heckl, WM; Geigl, JB Generation of chromosome painting probes from single chromosomes by laser microdissection and linker-adaptor PCR.
Chromosome Res. 2004; 12(4):337-343 Doi: 10.1023/B:CHRO.0000034132.77192.5f
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2003

Full paper/article (Journal)

** Jentsch, I; Geigl, J; Klein, CA; Speicher, MR Seven-fluorochrome mouse M-FISH for high-resolution analysis of interchromosomal rearrangements.
Cytogenet Genome Res. 2003; 103(1-2):84-88 Doi: 10.1159/000076294 [OPEN ACCESS]
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2002

Full paper/article (Journal)

** Klein, CA; Seidl, S; Petat-Dutter, K; Offner, S; Geigl, JB; Schmidt-Kittler, O; Wendler, N; Passlick, B; Huber, RM; Schlimok, G; Baeuerle, PA; Riethmüller, G Combined transcriptome and genome analysis of single micrometastatic cells.
Nat Biotechnol. 2002; 20(4):387-392 Doi: 10.1038/nbt0402-387
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