Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Vesely Paul |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2025
Originalarbeit (Zeitschrift)
** Peña, de, la, Sancha, P; Wieser, BI; Schauer, S; Reicher, H; Sattler, W; Breinbauer, R; Schweiger, M; Lechleitner, M; Frank, S; Zechner, R; Kratky, D; Espenshade, PJ; Hoefler, G; Vesely, PW
Lipolysis-derived fatty acids are needed for homeostatic control of sterol element-binding protein-1c driven hepatic lipogenesis.
Commun Biol. 2025; 8(1):588
Doi: 10.1038/s42003-025-08002-1
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2024
Originalarbeit (Zeitschrift)
** Chrysostomou, SE; Eder, S; Pototschnig, I; Mayer, AL; Derler, M; Mussbacher, M; Schauer, S; Zhang, DX; Yan, DM; Liu, GN; Hoefler, G; Weichhart, T; Vesely, PW; Zhang, LB; Schweiger, M
R-ketorolac ameliorates cancer-associated cachexia and prolongs survival of tumour-bearing mice
J CACHEXIA SARCOPENI. 2024;
Doi: 10.1002/jcsm.13422
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Abstract (Zeitschrift)
** Vesely, PW; Thanh, HPT; Kanti, M; Subramaniyan, B; Moore, A; Georgescu, C; Wren, JD; Freeman, WM; Syarif, AH; Schauer, S; Schweiger, M; Kwapiszewska, G; Hoefler, G; Walters, MS; Marsh, LM
Lipid-signaling as a Potential New Therapeutic Target in Chronic Obstructive Pulmonary Disease
AM J RESP CRIT CARE. 2024; 209: -ATS International Conference; MAY 17-22, 2024; San Diego, USA.
[Oral Communication]
Web of Science
2023
Originalarbeit (Zeitschrift)
** Pototschnig, I; Feiler, U; Diwoky, C; Vesely, PW; Rauchenwald, T; Paar, M; Bakiri, L; Pajed, L; Hofer, P; Kashofer, K; Sukhbaatar, N; Schoiswohl, G; Weichhart, T; Hoefler, G; Bock, C; Pichler, M; Wagner, EF; Zechner, R; Schweiger, M
Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia.
J Cachexia Sarcopenia Muscle. 2023; 14(1):93-107
Doi: 10.1002/jcsm.13109
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Abstract (Zeitschrift)
** Biasin, V; Osen, AS; Wojcik, G; Gindlhuber, J; Syarif, AH; Hoetzenecker, K; Böhm, P; Vesely, P; Bellusci, S; Marsh, LM; El Agha, E; Kwapiszewska, G
Lipids: are they able to alter lung fibrosis?
WIEN KLIN WOCHENSCHR. Abstracts. 2023; 135(19-20):580-580.-47. Jahrestagung der ÖGP - 7. Jahrestagung der ÖGTC; OCT 23-25, 2023; Graz, Austria.
[Poster]
Web of Science
2022
Originalarbeit (Zeitschrift)
** Kanti, MM; Striessnig-Bina, I; Wieser, BI; Schauer, S; Leitinger, G; Eichmann, TO; Schweiger, M; Winkler, M; Winter, E; Lana, A; Kufferath, I; Marsh, LM; Kwapiszewska, G; Zechner, R; Hoefler, G; Vesely, PW
Adipose triglyceride lipase-mediated lipid catabolism is essential for bronchiolar regeneration.
JCI Insight. 2022; 7(9):
Doi: 10.1172/jci.insight.149438
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2020
Originalarbeit (Zeitschrift)
** Alkan, HF; Vesely, PW; Hackl, H; Foßelteder, J; Schmidt, DR; Vander Heiden, MG; Pichler, M; Hoefler, G; Bogner-Strauss, JG
Deficiency of malate-aspartate shuttle component SLC25A12 induces pulmonary metastasis.
Cancer Metab. 2020; 8(1):26-26
Doi: 10.1186/s40170-020-00232-7
[OPEN ACCESS]
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** Xie, H; Heier, C; Kien, B; Vesely, PW; Tang, Z; Sexl, V; Schoiswohl, G; Strießnig-Bina, I; Hoefler, G; Zechner, R; Schweiger, M
Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020; 1865(9):158737-158737
Doi: 10.1016/j.bbalip.2020.158737
[OPEN ACCESS]
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2019
Originalarbeit (Zeitschrift)
** Pajed, L; Wagner, C; Taschler, U; Schreiber, R; Kolleritsch, S; Fawzy, N; Pototschnig, I; Schoiswohl, G; Pusch, LM; Wieser, BI; Vesely, P; Hoefler, G; Eichmann, TO; Zimmermann, R; Lass, A
Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation.
J Biol Chem. 2019; 294(23):9118-9133
Doi: 10.1074/jbc.RA118.007201
[OPEN ACCESS]
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2016
Originalarbeit (Zeitschrift)
** Al-Zoughbi, W; Pichler, M; Gorkiewicz, G; Guertl-Lackner, B; Haybaeck, J; Jahn, SW; Lackner, C; Liegl-Atzwanger, B; Popper, H; Schauer, S; Nusshold, E; Kindt, AS; Trajanoski, Z; Speicher, MR; Haemmerle, G; Zimmermann, R; Zechner, R; Vesely, PW; Hoefler, G
Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Oncotarget. 2016; 7(23):33832-33840
Doi: 10.18632/oncotarget.9418
[OPEN ACCESS]
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** Huang, J; Li, L; Lian, J; Schauer, S; Vesely, PW; Kratky, D; Hoefler, G; Lehner, R
Tumor-Induced Hyperlipidemia Contributes to Tumor Growth.
Cell Rep. 2016; 15(2): 336-348.
Doi: 10.1016/j.celrep.2016.03.020
[OPEN ACCESS]
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2015
Originalarbeit (Zeitschrift)
** Das, SK; Stadelmeyer, E; Schauer, S; Schwarz, A; Strohmaier, H; Claudel, T; Zechner, R; Hoefler, G; Vesely, PW
Micro RNA-124a regulates lipolysis via adipose triglyceride lipase and comparative gene identification 58.
Int J Mol Sci. 2015; 16(4):8555-8568
Doi: 10.3390/ijms16048555
[OPEN ACCESS]
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Übersichtsarbeit
** Schiefer, AI; Vesely, P; Hassler, MR; Egger, G; Kenner, L
The role of AP-1 and epigenetics in ALCL.
Front Biosci (Schol Ed). 2015; 7(5):226-235
Doi: 10.2741/436
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2013
Originalarbeit (Zeitschrift)
** Huang, J; Das, SK; Jha, P; Al Zoughbi, W; Schauer, S; Claudel, T; Sexl, V; Vesely, P; Birner-Gruenberger, R; Kratky, D; Trauner, M; Hoefler, G
The PPARα agonist fenofibrate suppresses B-cell lymphoma in mice by modulating lipid metabolism.
Biochim Biophys Acta. 2013; 1831(10):1555-1565
Doi: 10.1016/j.bbalip.2013.04.012
[OPEN ACCESS]
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** Huber, MD; Vesely, PW; Datta, K; Gerace, L
Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis.
J Cell Biol. 2013; 203(3):427-436
Doi: 10.1083/jcb.201305076
[OPEN ACCESS]
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2012
Originalarbeit (Zeitschrift)
** Laimer, D; Dolznig, H; Kollmann, K; Vesely, PW; Schlederer, M; Merkel, O; Schiefer, AI; Hassler, MR; Heider, S; Amenitsch, L; Thallinger, C; Staber, PB; Simonitsch-Klupp, I; Artaker, M; Lagger, S; Turner, SD; Pileri, S; Piccaluga, PP; Valent, P; Messana, K; Landra, I; Weichhart, T; Knapp, S; Shehata, M; Todaro, M; Sexl, V; Höfler, G; Piva, R; Medico, E; Ruggeri, BA; Cheng, M; Eferl, R; Egger, G; Penninger, JM; Jaeger, U; Moriggl, R; Inghirami, G; Kenner, L
PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
Nat Med. 2012; 18(11):1699-1704
Doi: 10.1038/nm.2966
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** Naji, S; Ambrus, G; Cimermančič, P; Reyes, JR; Johnson, JR; Filbrandt, R; Huber, MD; Vesely, P; Krogan, NJ; Yates, JR; Saphire, AC; Gerace, L
Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.
Mol Cell Proteomics. 2012; 11(4):M111.015313-M111.015313
Doi: 10.1074/mcp.M111.015313
[OPEN ACCESS]
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** Senanayake, U; Das, S; Vesely, P; Alzoughbi, W; Fröhlich, LF; Chowdhury, P; Leuschner, I; Hoefler, G; Guertl, B
miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms.
Carcinogenesis. 2012; 33(5):1014-1021
Doi: 10.1093/carcin/bgs126
[OPEN ACCESS]
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** Tamilarasan, KP; Temmel, H; Das, SK; Al Zoughbi, W; Schauer, S; Vesely, PW; Hoefler, G
Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity.
Cell Death Dis. 2012; 3(11):e354-e354
Doi: 10.1038/cddis.2012.91
[OPEN ACCESS]
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2011
Originalarbeit (Zeitschrift)
** Das, SK; Eder, S; Schauer, S; Diwoky, C; Temmel, H; Guertl, B; Gorkiewicz, G; Tamilarasan, KP; Kumari, P; Trauner, M; Zimmermann, R; Vesely, P; Haemmerle, G; Zechner, R; Hoefler, G
Adipose triglyceride lipase contributes to cancer-associated cachexia.
Science. 2011; 333(6039):233-238
Doi: 10.1126/science.1198973
[OPEN ACCESS]
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Abstract (Zeitschrift)
** Kenner, L; Laimer, D; Dolznig, H; Vesely, P; Kollmann, K; Schiefer, AII; Sexl, V; Staber, PB; Hoefler, G; Penninger, J; Inghirami, G; Ulrich, J
New and Highly Efficient Therapy for Treatment NPM-ALK Associated Lymphomas
BLOOD. 2011; 118(21): 721-721.
Web of Science
2009
Originalarbeit (Zeitschrift)
** Pflegerl, P; Vesely, P; Hantusch, B; Schlederer, M; Zenz, R; Janig, E; Steiner, G; Meixner, A; Petzelbauer, P; Wolf, P; Soleiman, A; Egger, G; Moriggl, R; Kishimoto, T; Wagner, EF; Kenner, L
Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling.
Proc Natl Acad Sci U S A. 2009; 106(48):20423-20428
Doi: 10.1073/pnas.0910371106
[OPEN ACCESS]
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Übersichtsarbeit
** Vesely, PW; Staber, PB; Hoefler, G; Kenner, L
Translational regulation mechanisms of AP-1 proteins.
Mutat Res. 2009; 682(1):7-12
Doi: 10.1016/j.mrrev.2009.01.001
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2007
Originalarbeit (Zeitschrift)
** Staber, PB; Vesely, P; Haq, N; Ott, RG; Funato, K; Bambach, I; Fuchs, C; Schauer, S; Linkesch, W; Hrzenjak, A; Dirks, WG; Sexl, V; Bergler, H; Kadin, ME; Sternberg, DW; Kenner, L; Hoefler, G
The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling.
Blood. 2007; 110(9):3374-3383
Doi: 10.1182/blood-2007-02-071258
[OPEN ACCESS]
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Abstract (Zeitschrift)
** Fuchs, C; Vesely, P; Bambach, I; Schauer, S; Linkesch, W; Stemberg, DW; Hoefler, G; Staber, PB
Identification of critical phosporylation sites within NPM-ALK that regulate JUNB mRNA translation
BLOOD. 2007; 110(11):1044A-1045A.-49 th Annual Meeting of the American Society of Hematology; NOV 8-11, 2007; Atlanta, Georgia, USA.
[Poster]
Web of Science
** Laimer, D; Vesely, P; Staber, P; Pflegerl, P; Brandes, R; Schlederer, M; Hoefler, G; Kenner, L
Role of junb in ALCL lymphoma development
HAEMATOL-HEMATOL J. 2007; 92: 344-344.Vienna.
[Poster]
Web of Science
** Moustafa, T; Fickert, P; Vesely, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Guelly, C; Trauner, M
Retention of toxic bile acids activate the mTOR, p70S6k/rps6 signaling pathway in mouse models of cholestatic liver injury
J HEPATOL. 2007; 46: S23-S23.
Doi: 10.1016/S0168-8278(07)61646-8
[Oral Communication]
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** Staber, P; Vesely, P; Fuchs, C; Bambach, I; Schauer, S; Bergler, H; Sternberg, D; Hoefler, G
The oncoprotein NPM-ALK induces translation of AP-1 factors via mTOR signalling
HAEMATOL-HEMATOL J. 2007; 92: 344-344.Vienna.
[Oral Communication]
Web of Science
** Staber, PB; Vesely, P; Fuchs, C; Schauer, S; Sternberg, DW; Hoefler, G
NPM-ALK induces JUNB and converts its role from a tumor suppressor to an oncogene
FEBS J. 2007; 274: 150-150.
[Poster]
Web of Science
** Vesely, P; Staber, P; Fuchs, C; Bambach, I; Schauer, S; Sternberg, D; Kenner, L; Hoefler, G
Expression of NPM-ALK leads to oncogenic effects of JunB
HAEMATOL-HEMATOL J. 2007; 92: 107-107.Vienna.
[Oral Communication]
Web of Science
** Vesely, P; Staber, PB; Fuchs, C; Schauer, S; Bergler, H; Sternberg, DW; Hoefler, G
Translational control of JUNB via the fusion tyrosine kinase NPM-ALK in ALC(L) lymphoma
FEBS J. 2007; 274: 150-150.
[Poster]
Web of Science
2006
Abstract (Zeitschrift)
** Staber, PB; Vesely, P; Ott, R; Haq, N; Linkesch, W; Schauer, S; Hrzenjak, A; Kenner, L; Dirks, W; Kadin, ME; Sternberg, DW; Hoefler, G
NPM-ALK fusion tyrosine kinase of anaplastic large cell lymphoma exerts its transforming potential by increasing translation of JUNB through mTOR and S6K1.
BLOOD. 2006; 108(11): 414A-415A.
Doi: 10.1182/blood.V108.11.1428.1428
[Poster]
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** Vesely, P; Staber, PB; Ott, R; Pinent, M; Linkesch, W; Schauer, S; Hrzenjak, A; Kadin, ME; Sternberg, DW; Hoefler, G
NPM-ALK converts JUNB from a tumor suppressor to an oncogene.
BLOOD. 2006; 108(11): 419A-420A.
Doi: 10.1182/blood.V108.11.1448.1448
[Poster]
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