Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Kashofer Karl |

** = Publikationen gelistet in SCI/SSCI/Pubmed

2025

Originalarbeit (Zeitschrift)

** Farzi, A; Tatzl, E; Kashofer, K; Trajanoski, S; Herbert, MK; Holzer, P Antibiotic-induced decrease of bacterial load in guinea pig intestine reduces α2-adrenoceptor expression and activity in peristaltic motor inhibition.
Br J Pharmacol. 2025; Doi: 10.1111/bph.70001
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** Jantus-Lewintre, E; Rappa, A; Ruano, D; van, Egmond, D; Gallach, S; Gozuyasli, D; Durães, C; Costa, JL; Camps, C; Lacroix, L; Kashofer, K; van, Wezel, T; Barberis, M Multicenter In-House Evaluation of an Amplicon-Based Next-Generation Sequencing Panel for Comprehensive Molecular Profiling.
Mol Diagn Ther. 2025; Doi: 10.1007/s40291-024-00766-2 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Joch, S; Smolle, MA; Kashofer, K; Thüringer, A; Szkandera, J; Benesch, M; El-Heliebi, A; Liegl-Atzwanger, B; Leithner, A; Seidel, MG New Insights from Long-Term Clinical Use of Circulating Tumor DNA-Based Minimal Residual Disease Monitoring in Translocation-Associated Sarcomas.
Oncol Res Treat. 2025; 48(4):186-196 Doi: 10.1159/000543223 [OPEN ACCESS]
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** Lara, Gutierrez, A; Halbwedl, I; Sauer, S; Regitnig, P; Petru, E; Seeböck, R; Schubert, S; Peternell, C; Bodó, K; Prein, K; Kashofer, K Robust assessment of HRD genomic instability by OncoScan microarrays.
J Mol Diagn. 2025; Doi: 10.1016/j.jmoldx.2025.02.011
PubMed FullText FullText_MUG

 

** Skok, K; Stift, J; Schirmacher, P; Kashofer, K; Stauber, R; Ranković, B; Lackner, K Molecular Landscape and Treatment Paradigms of Hepatocellular and Cholangiocarcinoma: A Multinational Review.
Z Gastroenterol. 2025; Doi: 10.1055/a-2548-0108
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Übersichtsarbeit

** Smolle, MA; Seidel, MG; Kashofer, K; Liegl-Atzwanger, B; Sadoghi, P; Müller, DA; Leithner, A Precision medicine in diagnosis, prognosis, and disease monitoring of bone and soft tissue sarcomas using liquid biopsy: a systematic review.
Arch Orthop Trauma Surg. 2025; 145(1): 121 Doi: 10.1007/s00402-024-05711-w [OPEN ACCESS]
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2024

Originalarbeit (Zeitschrift)

** Hamilton, G; Stickler, S; Ermakov, M; Eggerstorfer, MT; Nocera, FP; Hohenegger, M; Weigl, L; Hochmair, MJ; Kashofer, K Characterization of the BH1406 non-small cell lung cancer (NSCLC) cell line carrying an activating SOS1 mutation.
Transl Lung Cancer Res. 2024; 13(11):2987-2997 Doi: 10.21037/tlcr-24-570 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Reich, O; Regauer, S; Lara, Gutierrez, A; Kashofer, K Copy number profiling implicates thin high-grade squamous intraepithelial lesions as a true precursor of cervical human papillomavirus-induced squamous cell cancer.
Lab Invest. 2024; 102108 Doi: 10.1016/j.labinv.2024.102108
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** Wurm, S; Waltersdorfer, M; Loindl, S; Moritz, JM; Herzog, SA; Bachmaier, G; Berghold, A; Kashofer, K; Beham-Schmid, C; Hoefler, G; Greinix, HT; Wölfler, A; Reinisch, A; Sill, H; Zebisch, A Acute myeloid leukemia in the next-generation sequencing era : Real-world data from an Austrian tertiary cancer care center.
Wien Klin Wochenschr. 2024; Doi: 10.1007/s00508-024-02463-w
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** Zacharias, M; Konjic, S; Kratochwill, N; Absenger, G; Terbuch, A; Jost, PJ; Wurm, R; Lindenmann, J; Kashofer, K; Gollowitsch, F; Gorkiewicz, G; Brcic, L Expanding Broad Molecular Reflex Testing in Non-Small Cell Lung Cancer to Squamous Histology.
Cancers (Basel). 2024; 16(5): 903 Doi: 10.3390/cancers16050903 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Zacharias, M; Thüringer, A; Krause, R; Kashofer, K; Gorkiewicz, G The mutual value of histopathology and ITS sequencing in the diagnosis of mucormycosis.
Histopathology. 2024; 84(4):702-706 Doi: 10.1111/his.15131
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Übersichtsarbeit

** Ilié, M; Lake, V; de, Alava, E; Bonin, S; Chlebowski, S; Delort, A; Dequeker, E; Al-Dieri, R; Diepstra, A; Carpén, O; Eloy, C; Fassina, A; Fend, F; Fernandez, PL; Gorkiewicz, G; Heeke, S; Henrique, R; Hoefler, G; Huertas, P; Hummel, M; Kashofer, K; van, der, Laak, J; de, Pablos, RM; Schmitt, F; Schuuring, E; Stanta, G; Timens, W; Westphalen, B; Hofman, P Standardization through education of molecular pathology: a spotlight on the European Masters in Molecular Pathology.
Virchows Arch. 2024; 485(5):761-775 Doi: 10.1007/s00428-024-03933-2
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Abstract (Zeitschrift)

** Moik, F; Riedl, JM; Edlinger, L; Esterl, T; Hasenleithner, S; Kostmann, S; Cebular, L; Jahn, S; Kashofer, K; Zacharias, M; Hoefler, G; Heitzer, E; Gerger, A; Jost, PJ Practice patterns and treatment outcomes of molecular tumour board (MTB)-based personalized cancer therapies: A single-center experience
ANN ONCOL. 2024; 35: S262-S263. Doi: 10.1016/j.annonc.2024.08.130
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2023

Originalarbeit (Zeitschrift)

** Ermakov, MS; Kashofer, K; Regauer, S Different Mutational Landscape in HPV-induced and HPV-independent Invasive Penile Squamous Cell Cancers.
Mod Pathol. 2023; 100250 Doi: 10.1016/j.modpat.2023.100250
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** Foßelteder, J; Pabst, G; Sconocchia, T; Schlacher, A; Auinger, L; Kashofer, K; Beham-Schmid, C; Trajanoski, S; Waskow, C; Schöll, W; Sill, H; Zebisch, A; Wölfler, A; Thomas, D; Reinisch, A Human gene-engineered calreticulin mutant stem cells recapitulate MPN hallmarks and identify targetable vulnerabilities.
Leukemia. 2023; 37(4): 843-853. Doi: 10.1038/s41375-023-01848-6 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Hofman, P; Calabrese, F; Kern, I; Adam, J; Alarcão, A; Alborelli, I; Anton, NT; Arndt, A; Avdalyan, A; Barberis, M; Bégueret, H; Bisig, B; Blons, H; Boström, P; Brcic, L; Bubanovic, G; Buisson, A; Caliò, A; Cannone, M; Carvalho, L; Caumont, C; Cayre, A; Chalabreysse, L; Chenard, MP; Conde, E; Copin, MC; Côté, JF; D'Haene, N; Dai, HY; de, Leval, L; Delongova, P; Denčić-Fekete, M; Fabre, A; Ferenc, F; Forest, F; de, Fraipont, F; Garcia-Martos, M; Gauchotte, G; Geraghty, R; Guerin, E; Guerrero, D; Hernandez, S; Hurník, P; Jean-Jacques, B; Kashofer, K; Kazdal, D; Lantuejoul, S; Leonce, C; Lupo, A; Malapelle, U; Matej, R; Merlin, JL; Mertz, KD; Morel, A; Mutka, A; Normanno, N; Ovidiu, P; Panizo, A; Papotti, MG; Parobkova, E; Pasello, G; Pauwels, P; Pelosi, G; Penault-Llorca, F; Picot, T; Piton, N; Pittaro, A; Planchard, G; Poté, N; Radonic, T; Rapa, I; Rappa, A; Roma, C; Rot, M; Sabourin, JC; Salmon, I; Prince, SS; Scarpa, A; Schuuring, E; Serre, I; Siozopoulou, V; Sizaret, D; Smojver-Ježek, S; Solassol, J; Steinestel, K; Stojšić, J; Syrykh, C; Timofeev, S; Troncone, G; Uguen, A; Valmary-Degano, S; Vigier, A; Volante, M; Wahl, SGF; Stenzinger, A; Ilié, M Real-world EGFR testing practices for non-small-cell lung cancer by thoracic pathology laboratories across Europe.
ESMO Open. 2023; 8(5):101628 Doi: 10.1016/j.esmoop.2023.101628 [OPEN ACCESS]
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** Kashofer, K; Reich, O; Regauer, S Acquisition of Genetic Aberrations During the Progression of High-Grade Intraepithelial Lesions/Micro-Invasive Squamous Cancers to Widely Invasive Cervical Squamous Cell Cancer.
Arch Pathol Lab Med. 2023; Doi: 10.5858/arpa.2022-0310-OA
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** Pototschnig, I; Feiler, U; Diwoky, C; Vesely, PW; Rauchenwald, T; Paar, M; Bakiri, L; Pajed, L; Hofer, P; Kashofer, K; Sukhbaatar, N; Schoiswohl, G; Weichhart, T; Hoefler, G; Bock, C; Pichler, M; Wagner, EF; Zechner, R; Schweiger, M Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia.
J Cachexia Sarcopenia Muscle. 2023; 14(1):93-107 Doi: 10.1002/jcsm.13109 [OPEN ACCESS]
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** Regauer, S; Ermakov, M; Kashofer, K The Spectrum of HPV-independent Penile Intraepithelial Neoplasia: A Proposal for Subclassification.
Am J Surg Pathol. 2023; Doi: 10.1097/PAS.0000000000002130 [OPEN ACCESS]
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** Vitlarov, N; Burtscher, E; Pfeiffenberger, E; Wahl, A; Hodja, V; Jasarevic, Z; Kashofer, K; Offner, FA Peritoneal papillary mesothelioma in situ: BAP1 mutation with indolent behavior for 15 years.
VIRCHOWS ARCH. 2023; Doi: 10.1007/s00428-023-03593-8
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Fallbericht

** Trifina-Mikosch, E; Barta, J; Krampla, W; Freibauer, C; Lösch, G; Kashofer, K; Selkmann, S; Mikosch, P; Imhof, M Large cystic Abdominal Tumor caused by a low-grade Neoplasm of the Appendix
GEBURTSH FRAUENHEILK. 2023; 83(03): 261-265. Doi: 10.1055/a-1976-7797
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Abstract (Zeitschrift)

** Lewintre, EJ; Rappa, A; Ruano, D; Garcia, SG; Herrero, CJCC; Lacroix, L; Kashofer, K; van Wezel, T; Barberis, M Multicentric evaluation of amplicon-based next-generation sequencing solution for local comprehensive molecular tumor profiling
ANN ONCOL. 2023; 34: S269-S269.-Annual Meeting of the European-Society-for-Medical-Oncology (ESMO); OCT 20-24, 2023; Barcelona, SPAIN. Doi: 10.1016/j.annonc.2023.09.2942 [Poster]
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2022

Originalarbeit (Zeitschrift)

** Hassan, AM; Mancano, G; Kashofer, K; Liebisch, G; Farzi, A; Zenz, G; Claus, SP; Holzer, P Anhedonia induced by high-fat diet in mice depends on gut microbiota and leptin.
Nutr Neurosci. 2022; 25(2):299-312 Doi: 10.1080/1028415X.2020.1751508 [OPEN ACCESS]
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** Kashofer, K; Regauer, S; Reich, O; Petru, E; Winter, E Driver gene mutations in micro-invasive cervical squamous cancers have no prognostic significance.
Gynecol Oncol. 2022; 165(1):121-128 Doi: 10.1016/j.ygyno.2022.01.020
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** Regauer, S; Reich, O; Kashofer, K HPV-negative Squamous Cell Carcinomas of the Cervix With Special Focus on Intraepithelial Precursor Lesions.
AM J SURG PATHOL. 2022; 46(2): 147-158. Doi: 10.1097/PAS.0000000000001778
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** Regauer, S; Reich, O; Kashofer, K Cervical Precancers Originate From Infected Proliferating Reserve Cells: A Comparative Histologic and Genetic Study of Thin and Thick High-grade Squamous Intraepithelial Lesions.
Am J Surg Pathol. 2022; 46(4):519-527 Doi: 10.1097/PAS.0000000000001818
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** Riederer, M; Schweighofer, N; Trajanoski, S; Stelzer, C; Zehentner, M; Fuchs-Neuhold, B; Kashofer, K; Mayr, JA; Hörmann-Wallner, M; Holasek, S; van, der, Kleyn, M Free threonine in human breast milk is related to infant intestinal microbiota composition.
Amino Acids. 2022; 54(3):365-383 Doi: 10.1007/s00726-021-03057-w [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Seidel, MG; Kashofer, K; Moser, T; Thueringer, A; Liegl-Atzwanger, B; Leithner, A; Szkandera, J; Benesch, M; El-Heliebi, A; Heitzer, E Clinical implementation of plasma cell-free circulating tumor DNA quantification by digital droplet PCR for the monitoring of Ewing sarcoma in children and adolescents.
Front Pediatr. 2022; 10: 926405 Doi: 10.3389/fped.2022.926405 [OPEN ACCESS]
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** Suppan, C; Graf, R; Jahn, S; Zhou, Q; Klocker, EV; Bartsch, R; Terbuch, A; Kashofer, K; Regitnig, P; Lindenmann, J; Posch, F; Gerritsmann, H; Jost, PJ; Heitzer, E; Dandachi, N; Balic, M Sensitive and robust liquid biopsy-based detection of PIK3CA mutations in hormone-receptor-positive metastatic breast cancer patients.
Br J Cancer. 2022; 126(3):456-463 Doi: 10.1038/s41416-021-01601-9 [OPEN ACCESS]
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** Weber, T; Tatzl, E; Kashofer, K; Holter, M; Trajanoski, S; Berghold, A; Heinemann, A; Holzer, P; Herbert, MK Fibromyalgia-associated hyperalgesia is related to psychopathological alterations but not to gut microbiome changes.
PLoS One. 2022; 17(9):e0274026 Doi: 10.1371/journal.pone.0274026 [OPEN ACCESS]
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** Zacharias, M; Kashofer, K; Wurm, P; Regitnig, P; Schütte, M; Neger, M; Ehmann, S; Marsh, LM; Kwapiszewska, G; Loibner, M; Birnhuber, A; Leitner, E; Thüringer, A; Winter, E; Sauer, S; Pollheimer, MJ; Vagena, FR; Lackner, C; Jelusic, B; Ogilvie, L; Durdevic, M; Timmermann, B; Lehrach, H; Zatloukal, K; Gorkiewicz, G Host and microbiome features of secondary infections in lethal covid-19.
iScience. 2022; 25(9):104926 Doi: 10.1016/j.isci.2022.104926 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Brcic, L; Zacharias, M; Konjic, S; Kashofer, K; Absenger, G; Jost, PJ; Wurm, R; Lindenmann, J; Terbuch, A Molecular testing in lung squamous cell carcinoma using DNA- and RNA-based next-generation sequencing: A singlecenter experience
ANN ONCOL. 2022; 38(9): S1557-S1557. Doi: 10.1016/j.annonc.2022.10.344 [Poster]
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** Gutierrez, AL; Sauer, S; Kashofer, K OpenHRD - an open source platform for calculation of homologous recombination deficiency scores from OncoScan microarrays
VIRCHOWS ARCH. 2022; 481(SUPPL 1):S307-S307. [Poster]
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** Zacharias, M; Thuringer, A; Kashofer, K; Krause, R; Gorkiewicz, G Diagnostic value of ITS sequencing in mucormycosis - a retrospective single-centre study
VIRCHOWS ARCH. 2022; 481(SUPPL 1): S17-S18. [Oral Communication]
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Kommentar

** Regauer, S; Reich, O; Kashofer, K Correspondence on "Human papillomavirus-independent cervical cancer" by Fernandes et al
INT J GYNECOL CANCER. 2022; Doi: 10.1136/ijgc-2022-003368
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2021

Originalarbeit (Zeitschrift)

** Barennes, P; Quiniou, V; Shugay, M; Egorov, ES; Davydov, AN; Chudakov, DM; Uddin, I; Ismail, M; Oakes, T; Chain, B; Eugster, A; Kashofer, K; Rainer, PP; Darko, S; Ransier, A; Douek, DC; Klatzmann, D; Mariotti-Ferrandiz, E Benchmarking of T cell receptor repertoire profiling methods reveals large systematic biases.
Nat Biotechnol. 2021; 39(2):236-245 Doi: 10.1038/s41587-020-0656-3
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** Berg, JL; Perfler, B; Hatzl, S; Uhl, B; Reinisch, A; Pregartner, G; Berghold, A; Penz, T; Schuster, M; Geissler, K; Prokesch, A; Müller-Tidow, C; Hoefler, G; Kashofer, K; Wölfler, A; Sill, H; Caraffini, V; Zebisch, A EZH2 inactivation in RAS-driven myeloid neoplasms hyperactivates RAS-signaling and increases MEK inhibitor sensitivity.
Leukemia. 2021; 35(5):1521-1526 Doi: 10.1038/s41375-021-01161-0 [OPEN ACCESS]
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** Berger, M; Thueringer, A; Franz, D; Dandachi, N; Talakić, E; Richtig, G; Richtig, E; Rohrer, PM; Koch, L; Wolf, IH; Koch, C; Rainer, BM; Koeller, M; Pichler, M; Gerritsmann, H; Kashofer, K; Aigelsreiter, A Circulating Tumor DNA as a Marker for Treatment Response in Metastatic Melanoma Patients Using Next-Generation Sequencing-A Prospective Feasibility Study.
Cancers (Basel). 2021; 13(12): Doi: 10.3390/cancers13123101 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Brcic, I; Dawson, H; Gröchenig, HP; Högenauer, C; Kashofer, K Serrated Lesions in Inflammatory Bowel Disease: Genotype-Phenotype Correlation.
Int J Surg Pathol. 2021; 29(1):46-53 Doi: 10.1177/1066896920963798
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** Brčić, I; Godschachner, TM; Bergovec, M; Igrec, J; Till, H; Lackner, H; Scheipl, S; Kashofer, K; Brodowicz, T; Leithner, A; Szkandera, J; Liegl-Atzwanger, B Broadening the spectrum of NTRK rearranged mesenchymal tumors and usefulness of pan-TRK immunohistochemistry for identification of NTRK fusions.
Mod Pathol. 2021; 34(2):396-407 Doi: 10.1038/s41379-020-00657-x [OPEN ACCESS]
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** Kerr, DA; Thompson, LDR; Tafe, LJ; Jo, VY; Neyaz, A; Divakar, P; Paydarfar, JA; Pastel, DA; Shirai, K; John, I; Seethala, RR; Salgado, CM; Deshpande, V; Bridge, JA; Kashofer, K; Brčić, I; Linos, K Clinicopathologic and Genomic Characterization of Inflammatory Myofibroblastic Tumors of the Head and Neck: Highlighting a Novel Fusion and Potential Diagnostic Pitfall.
Am J Surg Pathol. 2021; 45(12):1707-1719 Doi: 10.1097/PAS.0000000000001735
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** Lohberger, B; Glänzer, D; Eck, N; Kerschbaum-Gruber, S; Mara, E; Deycmar, S; Madl, T; Kashofer, K; Georg, P; Leithner, A; Georg, D Activation of efficient DNA repair mechanisms after photon and proton irradiation of human chondrosarcoma cells.
Sci Rep. 2021; 11(1): 24116 Doi: 10.1038/s41598-021-03529-9 [OPEN ACCESS]
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** Riedl, JM; Hasenleithner, SO; Pregartner, G; Scheipner, L; Posch, F; Groller, K; Kashofer, K; Jahn, SW; Bauernhofer, T; Pichler, M; Stöger, H; Berghold, A; Hoefler, G; Speicher, MR; Heitzer, E; Gerger, A Profiling of circulating tumor DNA and tumor tissue for treatment selection in patients with advanced and refractory carcinoma: a prospective, two-stage phase II Individualized Cancer Treatment trial.
Ther Adv Med Oncol. 2021; 13:1758835920987658 Doi: 10.1177/1758835920987658 [OPEN ACCESS]
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** Schrom, S; Hebesberger, T; Wallner, SA; Anders, I; Richtig, E; Brandl, W; Hirschmugl, B; Garofalo, M; Bernecker, C; Schlenke, P; Kashofer, K; Wadsack, C; Aigelsreiter, A; Heitzer, E; Riedl, S; Zweytick, D; Kretschmer, N; Richtig, G; Rinner, B MUG Mel3 Cell Lines Reflect Heterogeneity in Melanoma and Represent a Robust Model for Melanoma in Pregnancy.
Int J Mol Sci. 2021; 22(21): Doi: 10.3390/ijms222111318 [OPEN ACCESS]
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** Toferer, A; Truschnegg, A; Kashofer, K; Beham-Schmid, C; Beham, A First presentation of a frameshift mutation in the SETD2 gene of a juvenile psammomatoid ossifying fibroma (JPOF) associated with an aneurysmal bone cyst.
DIAGN PATHOL. 2021; 16(1): 91 Doi: 10.1186/s13000-021-01160-w (- Case Report) [OPEN ACCESS]
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** Traussnigg, S; Halilbasic, E; Hofer, H; Munda, P; Stojakovic, T; Fauler, G; Kashofer, K; Krssak, M; Wolzt, M; Trauner, M Open-label phase II study evaluating safety and efficacy of the non-steroidal farnesoid X receptor agonist PX-104 in non-alcoholic fatty liver disease.
Wien Klin Wochenschr. 2021; 133(9-10):441-451 Doi: 10.1007/s00508-020-01735-5 [OPEN ACCESS]
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** Zacharias, M; Absenger, G; Kashofer, K; Wurm, R; Lindenmann, J; Terbuch, A; Konjic, S; Sauer, S; Gollowitsch, F; Gorkiewicz, G; Brcic, L Reflex testing in non-small cell lung carcinoma using DNA-and RNA-based next-generation sequencing-a single-center experience
TRANSL LUNG CANCER R. 2021; Doi: 10.21037/tlcr-21-570 [OPEN ACCESS]
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Kurzbericht/Letter

** Zacharias, M; Stangl, V; Thüringer, A; Loibner, M; Wurm, P; Wolfgruber, S; Zatloukal, K; Kashofer, K; Gorkiewicz, G Rapid Antigen Test for Postmortem Evaluation of SARS-CoV-2 Carriage.
Emerg Infect Dis. 2021; 27(6):1734-1737 Doi: 10.3201/eid2706.210226 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Foßelteder, J; Schlacher, A; Pabst, G; Amtmann, B; Schöll, W; Kashofer, K; Beham-Schmid, C; Schlenke, P; Greinix, HT; Sill, H; Woelfler, A; Zebisch, A; Reinisch, A Introduction and Genetic Correction of Calreticulin Mutations in Human Hematopoietic Stem and Progenitor Cells Sheds Light on MPN Pathogenesis
Blood. 2021; 138(S1):-Annual Meeting of the American Society of Hematology (ASH); DEC 11-14, 2021; Atlanta, USA. Doi: 10.1182/blood-2021-147919 [Poster]
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** Pabst, G; Foßelteder, J; Schlacher, A; Auinger, L; Martinez-Krams3, D; Ediriwickrema, A; Kashofer, K; Beham-Schmid, C; Greinix, HT; Woelfler, A; Schlenke, P; Sill, H; Zebisch, A; Majeti, R; Reinisch, A Modeling the Development of SRSF2 Mutated Myeloid Malignancies By CRISPR/Cas9 Mediated Genome Engineering of Primary Human Hematopoietic Stem and Progenitor Cells
Blood. 2021; 138(S1):-Annual Meeting of the American Society of Hematology (ASH); DEC 11-14, 2021; Atlanta, USA. Doi: 10.1182/blood-2021-149591 [Poster]
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** Popper, H; Zacharias, M; Brcic, L; Marsh, L; Lehrach, H; Schutte, M; Kwapiszewska, G; Timmermann, B; Kashofer, K; Nerlich, A; Regitnig, P; Kenner, L; Zatloukal, K Different types of immune system regulations in severe Coronavirus disease 2019
VIRCHOWS ARCH. 2021; 479(SUPPL 1):S50-S50. [Onlinepräsentation]
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** Suppan, C; Zhou, Q; Jahn, S; Graf, R; Klocker, EV; Terbuch, A; Kashofer, K; Posch, F; Gerritsmann, H; Dandachi, N; Heitzer, E; Balic, M Comparison of liquid biopsy and tissue based detection of PIK3CAmutations in HR positive metastatic breast cancer patients
CANCER RES. 2021; 81(4): [Poster]
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2020

Originalarbeit (Zeitschrift)

** Brcic, L; Fakler, F; Eidenhammer, S; Thueringer, A; Kashofer, K; Kulka, J; Popper, H Pleuropulmonary blastoma type I might arise in congenital pulmonary airway malformation type 4 by acquiring a Dicer 1 mutation.
Virchows Arch. 2020; Doi: 10.1007/s00428-020-02789-6 [OPEN ACCESS]
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** Brčić, I; Brodowicz, T; Cerroni, L; Kashofer, K; Serbanescu, GL; Kasseroler, MT; Amann, G; Scheipl, S; Szkandera, J; Leithner, A; Liegl-Atzwanger, B Undifferentiated round cell sarcomas with CIC-DUX4 gene fusion: expanding the clinical spectrum.
Pathology. 2020; 52(2):236-242 Doi: 10.1016/j.pathol.2019.09.015 [OPEN ACCESS]
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** Brčić, I; Yamani, F; Inwards, CY; Sumathi, V; Dodd, L; Kreiger, PA; Sittampalam, K; Allred, TR; Kashofer, K; Liegl-Atzwanger, B; Kerr, DA; Nielsen, GP; Rosenberg, AE Giant Cell Tumor of Bone With Cartilage Matrix: A Clinicopathologic Study of 17 Cases.
Am J Surg Pathol. 2020; 44(6): 748-756. Doi: 10.1097/PAS.0000000000001446 [OPEN ACCESS]
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** Brodowicz, T; Liegl-Atzwanger, B; Penel, N; Mir, O; Blay, JY; Kashofer, K; Le Cesne, A; Decoupigny, E; Wallet, J; Hamacher, R; Deley, ML Assessing Prognostic and Predictive Biomarkers of Regorafenib Response in Patients with Advanced Soft Tissue Sarcoma: REGOSARC Study.
Cancers (Basel). 2020; 12(12): Doi: 10.3390/cancers12123746 [OPEN ACCESS]
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** Caraffini, V; Geiger, O; Rosenberger, A; Hatzl, S; Perfler, B; Berg, JL; Lim, C; Strobl, H; Kashofer, K; Schauer, S; Beham-Schmid, C; Hoefler, G; Geissler, K; Quehenberger, F; Kolch, W; Athineos, D; Blyth, K; Wölfler, A; Sill, H; Zebisch, A Loss of RAF kinase inhibitor protein is involved in myelomonocytic differentiation and aggravates RAS-driven myeloid leukemogenesis.
Haematologica. 2020; 105(2):375-386 Doi: 10.3324/haematol.2018.209650 [OPEN ACCESS]
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** Cvitic, S; Strutz, J; Appel, HM; Weiß, E; Brandl, WT; Thüringer, A; Bernhart, EM; Lassance, L; Wadsack, C; Schliefsteiner, C; Sreckovic, I; Kashofer, K; Hiden, U Sexual dimorphism of miRNA signatures in feto-placental endothelial cells is associated with altered barrier function and actin organization.
Clin Sci (Lond). 2020; 134(1): 39-51. Doi: 10.1042/CS20190379 [OPEN ACCESS]
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** Daga, S; Rosenberger, A; Kashofer, K; Heitzer, E; Quehenberger, F; Halbwedl, I; Graf, R; Krisper, N; Prietl, B; Höfler, G; Reinisch, A; Zebisch, A; Sill, H; Wölfler, A Sensitive and broadly applicable residual disease detection in acute myeloid leukemia using flow cytometry-based leukemic cell enrichment followed by mutational profiling.
Am J Hematol. 2020; 95(10):1148-57 Doi: 10.1002/ajh.25918 [OPEN ACCESS]
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** Fakler, F; Aykutlu, U; Brcic, L; Eidenhammer, S; Thueringer, A; Kashofer, K; Kulka, J; Timens, W; Popper, H Atypical goblet cell hyperplasia occurs in CPAM 1, 2, and 3, and is a probable precursor lesion for childhood adenocarcinoma.
Virchows Arch. 2020; 476(6):843-854 Doi: 10.1007/s00428-019-02732-4
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** Guenter, S; Gorkiewicz, G; Halwachs, B; Kashofer, K; Thueringer, A; Wurm, P; Zollner-Schwetz, I; Valentin, T; Prattes, J; Wunsch, S; Ullrich, E; Zurl, C; Hoenigl, M; Krause, R Impact of ITS-Based Sequencing on Antifungal Treatment of Patients with Suspected Invasive Fungal Infections.
J Fungi (Basel). 2020; 6(2): Doi: 10.3390/jof6020043 [OPEN ACCESS]
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** Jačan, A; Kashofer, K; Zenz, G; Fröhlich, EE; Reichmann, F; Hassan, AM; Holzer, P Synergistic and antagonistic interactions between antibiotics and synbiotics in modifying the murine fecal microbiome.
Eur J Nutr. 2020; 59(5):1831-1844 Doi: 10.1007/s00394-019-02035-z [OPEN ACCESS]
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** Moser, T; Waldispuehl-Geigl, J; Belic, J; Weber, S; Zhou, Q; Hasenleithner, SO; Graf, R; Terzic, JA; Posch, F; Sill, H; Lax, S; Kashofer, K; Hoefler, G; Schoellnast, H; Heitzer, E; Geigl, JB; Bauernhofer, T; Speicher, MR On-treatment measurements of circulating tumor DNA during FOLFOX therapy in patients with colorectal cancer.
NPJ Precis Oncol. 2020; 4(1):30 Doi: 10.1038/s41698-020-00134-3 [OPEN ACCESS]
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** Reich, O; Regauer, S; Kashofer, K Possibly carcinogenic HPV subtypes are a cause of HSIL and negative clinical HPV tests - A European prospective single center study.
Gynecol Oncol. 2020; 158(1):112-116 Doi: 10.1016/j.ygyno.2020.04.685
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** Strasser, C; Spindelboeck, W; Kashofer, K; Oswald, J; Haid, B Low-dose antibiotic prophylaxis has no significant impact on the stability of the intestinal microbiome in children with urogenital tract malformations under 1 year of age.
J Pediatr Urol. 2020; 16(4):456.e1-456456 Doi: 10.1016/j.jpurol.2020.05.165 [OPEN ACCESS]
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** Weber, S; Spiegl, B; Perakis, SO; Ulz, CM; Abuja, PM; Kashofer, K; Leest, PV; Azpurua, MA; Tamminga, M; Brudzewsky, D; Rothwell, DG; Mohan, S; Sartori, A; Lampignano, R; Konigshofer, Y; Sprenger-Haussels, M; Wikman, H; Bergheim, IR; Kloten, V; Schuuring, E; Speicher, MR; Heitzer, E Technical Evaluation of Commercial Mutation Analysis Platforms and Reference Materials for Liquid Biopsy Profiling.
Cancers (Basel). 2020; 12(6): 1588 Doi: 10.3390/cancers12061588 [OPEN ACCESS]
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Kurzbericht/Letter

** Sunitsch, S; Reisinger, J; Abete, L; Kashofer, K; Regitnig, P Metaplastic papillary tumour of the fallopian tube, a rare entity, analysed by next-generation sequencing.
Histopathology. 2020; 76(6):923-924 Doi: 10.1111/his.14043 [OPEN ACCESS]
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** Zebisch, A; Winter, G; Kashofer, K; Hatzl, S; Uhl, B; Wurm, S; Wölfler, A; Greinix, HT; Hoefler, G; Sill, H The role of germline mutation profiling in the selection of related donors for haematopoietic stem cell transplantation.
Bone Marrow Transplant. 2020; 55(7):1502-1505 Doi: 10.1038/s41409-019-0691-1 [OPEN ACCESS]
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Übersichtsarbeit

** List, W; Regitnig, P; Kashofer, K; Gorkiewicz, G; Zacharias, M; Wedrich, A; Posch-Pertl, L Occurrence of SARS-CoV-2 in the intraocular milieu.
Exp Eye Res. 2020; 201:108273 Doi: 10.1016/j.exer.2020.108273 [OPEN ACCESS]
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** Timar, J; Kashofer, K Molecular epidemiology and diagnostics of KRAS mutations in human cancer.
Cancer Metastasis Rev. 2020; 39(4):1029-1038 Doi: 10.1007/s10555-020-09915-5 [OPEN ACCESS]
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Fallbericht

** Igrec, J; Brčić, I; Igrec, R; Bergovec, M; Kashofer, K; Fuchsjäger, M; Leithner, A; Liegl-Atzwanger, B Intraarticular Nodular Fasciitis of the Knee With MHY9-USP6 Fusion: A Case Report.
Int J Surg Pathol. 2020; 28(6):672-677 Doi: 10.1177/1066896920908054 (- Case Report)
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Abstract (Zeitschrift)

** Berger, M; Thueringer, A; Franz, D; Dandachi, N; Talakic, E; Richtig, G; Richtig, E; Rohrer, P; Koch, L; Wolf, I; Koch, C; Rainer, B; Koeller, M; Pichler, M; Kashofer, K; Aigelsreiter, A Feasibility and first results of circulating tumor DNA as a marker for treatment response in metastatic melanoma patients using Next Generation Sequencing.
ONCOL RES TREAT. 2020; 43(SUPPL 4):166-167. [Onlinepräsentation]
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** Gerger, A; Riedl, JM; Perakis, S; Pregartner, G; Scheipner, L; Posch, F; Groller, K; Kashofer, K; Jahn, SW; Bauernhofer, T; Pichler, M; Stoger, H; Berghold, A; Hofler, G; Speicher, M; Heitzer, E Profiling of circulating tumour DNA for treatment selection in patients with advanced and refractory carcinoma: A prospective, two-stage phase II individualized cancer treatment trial.
ANN ONCOL. 2020; 31: S1095-S1096.-ESMO Virtual Congress; SEP 19-OCT 18, 2020; ELECTR NETWORK. Doi: 10.1016/j.annonc.2020.08.1331 [Onlinepräsentation] [OPEN ACCESS]
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** Moser, T; Waldispuehl-Geigl, J; Belic, J; Perakis, S; Weber, S; Zhou, Q; Sill, H; Lax, S; Kashofer, K; Hoefler, G; Schoellnast, H; Bauernhofer, T; Heitzer, E; Geigl, JB; Speicher, MR Early circulating tumor DNA dynamics as a real-time predictor of FOLFOX efficacy in advanced colorectal cancer patients
CANCER RES. 2020; 80(16): Doi: 10.1158/1538-7445.AM2020-4295 [Poster]
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** Riedl, J; Perakis, S; Pregartner, G; Scheipner, L; Posch, F; Groller, K; Kashofer, K; Jahn, SW; Bauernhofer, T; Pichler, M; Stoger, H; Berghold, A; Hofler, G; Speicher, M; Heitzer, E; Gerger, A Individualized cancer treatment based on molecular profiling of circulating tumor DNA in patients with advanced and refractory carcinoma: a prospective phase II trial.
ONCOL RES TREAT. 2020; 43(SUPPL 4):249-249.-DGHO Jahrestagung; 09.10. -11.10.2020; Basel (virtueller Kongress). [Oral Communication]
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2019

Originalarbeit (Zeitschrift)

** Bengesser, SA; Mörkl, S; Painold, A; Dalkner, N; Birner, A; Fellendorf, FT; Platzer, M; Queissner, R; Hamm, C; Maget, A; Pilz, R; Rieger, A; Wagner-Skacel, J; Reininghaus, B; Kapfhammer, HP; Petek, E; Kashofer, K; Halwachs, B; Holzer, P; Waha, A; Reininghaus, EZ Epigenetics of the molecular clock and bacterial diversity in bipolar disorder.
Psychoneuroendocrinology. 2019; 101(6):160-166 Doi: 10.1016/j.psyneuen.2018.11.009
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** Brcic, I; Kashofer, K; Skone, D; Liegl-Atzwanger, B KIT mutation in a naïve succinate dehydrogenase-deficient gastric GIST.
Genes Chromosomes Cancer. 2019; 58(11):798-803 Doi: 10.1002/gcc.22768 [OPEN ACCESS]
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** Castellani, C; Singer, G; Eibisberger, M; Obermüller, B; Warncke, G; Miekisch, W; Kolb-Lenz, D; Summer, G; Pauer, TM; ElHaddad, A; Kashofer, K; Till, H The effects of neuroblastoma and chemotherapy on metabolism, fecal microbiome, volatile organic compounds, and gut barrier function in a murine model.
Pediatr Res. 2019; 85(4):546-555 Doi: 10.1038/s41390-019-0283-1 [OPEN ACCESS]
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** Chen, S; Tauber, G; Langsenlehner, T; Schmölzer, LM; Pötscher, M; Riethdorf, S; Kuske, A; Leitinger, G; Kashofer, K; Czyż, ZT; Polzer, B; Pantel, K; Sedlmayr, P; Kroneis, T; El-Heliebi, A In Vivo Detection of Circulating Tumor Cells in High-Risk Non-Metastatic Prostate Cancer Patients Undergoing Radiotherapy.
Cancers (Basel). 2019; 11(7): Doi: 10.3390/cancers11070933 [OPEN ACCESS]
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** Hassan, AM; Mancano, G; Kashofer, K; Fröhlich, EE; Matak, A; Mayerhofer, R; Reichmann, F; Olivares, M; Neyrinck, AM; Delzenne, NM; Claus, SP; Holzer, P High-fat diet induces depression-like behaviour in mice associated with changes in microbiome, neuropeptide Y, and brain metabolome.
Nutr Neurosci. 2019; 22(12):877-893 Doi: 10.1080/1028415X.2018.1465713 [OPEN ACCESS]
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** Heitzer, E; Groenewoud, A; Meditz, K; Lohberger, B; Liegl-Atzwanger, B; Prokesch, A; Kashofer, K; Behrens, D; Haybaeck, J; Kolb-Lenz, D; Koefeler, H; Riedl, S; Schaider, H; Fischer, C; Snaar-Jagalska, BE; de'Jong, D; Szuhai, K; Zweytick, D; Rinner, B Human melanoma brain metastases cell line MUG-Mel1, isolated clones and their detailed characterization.
Sci Rep. 2019; 9(1):4096-4096 Doi: 10.1038/s41598-019-40570-1 [OPEN ACCESS]
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** Mörkl, S; Lackner, S; Meinitzer, A; Gorkiewicz, G; Kashofer, K; Painold, A; Holl, A; Holasek, S [Pilot study: Gut microbiome and intestinal barrier in anorexia nervosa].
Fortschr Neurol Psychiatr. 2019; 87(1):39-45 Doi: 10.1055/s-0043-123826
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** Painold, A; Mörkl, S; Kashofer, K; Halwachs, B; Dalkner, N; Bengesser, S; Birner, A; Fellendorf, F; Platzer, M; Queissner, R; Schütze, G; Schwarz, MJ; Moll, N; Holzer, P; Holl, AK; Kapfhammer, HP; Gorkiewicz, G; Reininghaus, EZ A step ahead: Exploring the gut microbiota in inpatients with bipolar disorder during a depressive episode.
Bipolar Disord. 2019; 21(1):40-49 Doi: 10.1111/bdi.12682 [OPEN ACCESS]
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** Regauer, S; Kashofer, K; Reich, O Time series analysis of TP53 gene mutations in recurrent HPV-negative vulvar squamous cell carcinoma
MODERN PATHOL. 2019; 32(3): 415-422. Doi: 10.1038/s41379-018-0141-4 [OPEN ACCESS]
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** Regauer, S; Reich, O; Kashofer, K Thin variant of high-grade squamous intraepithelial lesion - relationship with high-risk and possibly carcinogenic human papilloma virus subtypes and somatic cancer gene mutations.
HISTOPATHOLOGY. 2019; 75(3): 405-412. Doi: 10.1111/his.13869 [OPEN ACCESS]
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** Safari, Z; Monnoye, M; Abuja, PM; Mariadassou, M; Kashofer, K; Gérard, P; Zatloukal, K Steatosis and gut microbiota dysbiosis induced by high-fat diet are reversed by 1-week chow diet administration.
Nutr Res. 2019; 71: 72-88. Doi: 10.1016/j.nutres.2019.09.004 [OPEN ACCESS]
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** Till, H; Kashofer, K; Laje, P; ElHaddad, A; Warncke, G; Gorkiewicz, G; Singer, G Microbial Evidence in Congenital Pulmonary Airway Malformations of Young Asymptomatic Infants.
J Laparoendosc Adv Surg Tech A. 2019; Doi: 10.1089/lap.2017.0456
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Kurzbericht/Letter

** Müller, M; Graf, R; Kashofer, K; Macher, S; Wölfler, A; Zebisch, A; Hrzenjak, A; Heitzer, E; Sill, H Detection of AML-specific TP53 mutations in bone marrow-derived mesenchymal stromal cells cultured under hypoxia conditions.
Ann Hematol. 2019; 98(8):2019-2020 Doi: 10.1007/s00277-019-03680-4 [OPEN ACCESS]
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Übersichtsarbeit

** Smolle, MA; Kashofer, K; Riedl, JM; Stotz, M; Gerger, A Genetic Analysis Using a Gene Panel in 87 Caucasian Patients With Colorectal Cancer: Own Results and Review of Literature.
Anticancer Res. 2019; 39(2): 847-852. Doi: 10.21873/anticanres.13184
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Abstract (Zeitschrift)

** Brcic, I; Dawson, H; Grochenig, HP; Hogenauer, C; Kashofer, K; Langner, C Serrated Lesions In Inflammatory Bowel Disease: Genotype-Phenotype Correlation
MODERN PATHOL. 2019; 32: -108th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP) - Unlocking Your Ingenuity; MAR 16-21, 2019; National Harbor, MD, USA. [Poster]
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** Brcic, I; Dawson, H; Grochenig, HP; Hogenauer, C; Kashofer, K; Langner, C Serrated Lesions In Inflammatory Bowel Disease: Genotype-Phenotype Correlation
LAB INVEST. 2019; 99: -108th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP) - Unlocking Your Ingenuity; MAR 16-21, 2019; National Harbor, MD, USA. [Poster]
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** Brcic, I; Kashofer, K; Liegl-Atzwanger, B Succinate Dehydrogenase-Deficient Gastric Gist With An Additional KIT Mutation
MODERN PATHOL. 2019; 32: -108th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP) - Unlocking Your Ingenuity; MAR 16-21, 2019; National Harbor, MD, USA. [Poster]
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** Brcic, I; Kashofer, K; Liegl-Atzwanger, B Succinate Dehydrogenase-Deficient Gastric Gist With An Additional KIT Mutation
LAB INVEST. 2019; 99: -108th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP) - Unlocking Your Ingenuity; MAR 16-21, 2019; National Harbor, MD, USA. [Poster]
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** Dandachi, N; Absenger, G; Brcic, L; Kashofer, K; Terbuch, A; Jaritz, L; Stanzer, S; Balic, M Feasibility and clinical value of serial circulating tumor DNA testing in metastatic lung adenocarcinoma patients undergoing TKI treatment
ONCOL RES TREAT. 2019; 42: 213-213. [Poster]
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** Kashofer, K; Thueringer, A; Brcic, L; Gorkiewicz, G Pulmonary amoebic abscess - resolved with application of metagenomics (universal pathogen detection).
VIRCHOWS ARCH. 2019; 475: S119-S119.-31st European Congress of Pathology; SEP 7-11, 2019; Nice, FRANCE. [Poster]
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** Perakis, SO; Ulz, P; Riedl, JM; Scheipner, L; Kashofer, K; Hoefler, G; Geigl, JB; Speicher, MR; Heitzer, E; Gerger, A Molecular-biological tumor profiling for drug treatment selection in patients with advanced and refractory carcinoma: A prospective, two-stage Phase II individualized cancer treatment study
CANCER RES. 2019; 79(13):-Annual Meeting of the American-Association-for-Cancer-Research (AACR); MAR 29-APR 03, 2019; Atlanta, GA. Doi: 10.1158/1538-7445.AM2019-CT130 [Poster]
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** Zacharias, M; Brcic, L; Kashofer, K; Gorkiewicz, G Inflammatory pseudotumour of the chest - a medical conundrum solved with 16S rRNA gene sequencing.
Virchows Archiv. 2019; 475: S121-S121.-31st European Congress of Pathology; SEP 7-11, 2019; Nice, FRANCE. [Poster]
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** Zacharias, M; Brcic, L; Kashofer, K; Gorkiewicz, G Pulmonary nocardiosis diagnosed by panbacterial (16S rRNA gene) sequencing - a series of 3 cases.
Virchows Archiv. 2019; 475: S121-S121.-31st European Congress of Pathology; SEP 7-11, 2019; Nice, FRANCE. [Poster]
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2018

Originalarbeit (Zeitschrift)

** Caraffini, V; Perfler, B; Berg, JL; Uhl, B; Schauer, S; Kashofer, K; Ghaffari-Tabrizi-Wizsy, N; Strobl, H; Wölfler, A; Hoefler, G; Sill, H; Zebisch, A Loss of RKIP is a frequent event in myeloid sarcoma and promotes leukemic tissue infiltration.
Blood. 2018; 131(7): 826-830. Doi: 10.1182/blood-2017-09-804906 [OPEN ACCESS]
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** Chen, S; El-Heliebi, A; Schmid, J; Kashofer, K; Czyż, ZT; Polzer, BM; Pantel, K; Kroneis, T; Sedlmayr, P Target Cell Pre-enrichment and Whole Genome Amplification for Single Cell Downstream Characterization.
J Vis Exp. 2018; (135): Doi: 10.3791/56394 [OPEN ACCESS]
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** Fuchs, CD; Paumgartner, G; Mlitz, V; Kunczer, V; Halilbasic, E; Leditznig, N; Wahlström, A; Ståhlman, M; Thüringer, A; Kashofer, K; Stojakovic, T; Marschall, HU; Trauner, M Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2-/- mice by modulating composition, signalling and excretion of faecal bile acids.
Gut. 2018; 67(9):1683-1691 Doi: 10.1136/gutjnl-2017-314553 [OPEN ACCESS]
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** Gaksch, L; Kashofer, K; Heitzer, E; Quehenberger, F; Daga, S; Hofer, S; Halbwedl, I; Graf, R; Krisper, N; Hoefler, G; Zebisch, A; Sill, H; Wölfler, A Residual disease detection using targeted parallel sequencing predicts relapse in cytogenetically normal acute myeloid leukemia.
Am J Hematol. 2018; 93(1):23-30 Doi: 10.1002/ajh.24922 [OPEN ACCESS]
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** Graffmann, N; Bohndorf, M; Ncube, A; Kawala, MA; Wruck, W; Kashofer, K; Zatloukal, K; Adjaye, J Establishment and characterization of an iPSC line from a 35 years old high grade patient with nonalcoholic fatty liver disease (30-40% steatosis) with homozygous wildtype PNPLA3 genotype.
Stem Cell Res. 2018; 31: 113-116. Doi: 10.1016/j.scr.2018.07.015 [OPEN ACCESS]
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** Matak, A; Lahiri, P; Ford, E; Pabst, D; Kashofer, K; Stellas, D; Thanos, D; Zatloukal, K Stochastic phenotype switching leads to intratumor heterogeneity in human liver cancer.
Hepatology. 2018; 68(3):933-948 Doi: 10.1002/hep.29679 [OPEN ACCESS]
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** Mörkl, S; Lackner, S; Meinitzer, A; Mangge, H; Lehofer, M; Halwachs, B; Gorkiewicz, G; Kashofer, K; Painold, A; Holl, AK; Bengesser, SA; Müller, W; Holzer, P; Holasek, SJ Gut microbiota, dietary intakes and intestinal permeability reflected by serum zonulin in women.
Eur J Nutr. 2018; 57(8):2985-2997 Doi: 10.1007/s00394-018-1784-0 [OPEN ACCESS]
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** Singer, G; Kashofer, K; Castellani, C; Till, H Hirschsprung's Associated Enterocolitis (HAEC) Personalized Treatment with Probiotics Based on Gene Sequencing Analysis of the Fecal Microbiome.
Case Rep Pediatr. 2018; 2018:3292309-3292309 Doi: 10.1155/2018/3292309 [OPEN ACCESS]
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** Strutz, J; Cvitic, S; Hackl, H; Kashofer, K; Appel, HM; Thüringer, A; Desoye, G; Koolwijk, P; Hiden, U Gestational diabetes alters microRNA signatures in human feto-placental endothelial cells depending on fetal sex.
Clin Sci (Lond). 2018; 132(22):2437-2449 Doi: 10.1042/CS20180825
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** Sunitsch, S; Gilg, MM; Kashofer, K; Gollowitsch, F; Leithner, A; Liegl-Atzwanger, B Detection of GNAS mutations in intramuscular / cellular myxomas as diagnostic tool in the classification of myxoid soft tissue tumors.
Diagn Pathol. 2018; 13(1): 52-52. Doi: 10.1186/s13000-018-0734-8 [OPEN ACCESS]
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** Zhong, Q; Wagner, U; Kurt, H; Molinari, F; Cathomas, G; Komminoth, P; Barman-Aksözen, J; Schneider-Yin, X; Rey, JP; Vassella, E; Rogel, U; Diebold, J; McKee, T; Jochum, W; Kashofer, K; Hofman, P; Zischka, M; Moch, H; Rechsteiner, M; Wild, PJ Multi-laboratory proficiency testing of clinical cancer genomic profiling by next-generation sequencing.
Pathol Res Pract. 2018; 214(7):957-963 Doi: 10.1016/j.prp.2018.05.020
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Kurzbericht/Letter

** Giuffrida, R; Kashofer, K; Dika, E; Patrizi, A; Baraldi, C; Di Meo, N; Zalaudek, I Fast growing melanoma following treatment with vismodegib for locally advanced basal cell carcinomas: report of two cases.
Eur J Cancer. 2018; 91(2):177-179 Doi: 10.1016/j.ejca.2017.11.031 (- Case Report)
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** Kashofer, K; Gornicec, M; Lind, K; Caraffini, V; Schauer, S; Beham-Schmid, C; Wölfler, A; Hoefler, G; Sill, H; Zebisch, A Detection of prognostically relevant mutations and translocations in myeloid sarcoma by next generation sequencing.
Leuk Lymphoma. 2018; 59(2):501-504 Doi: 10.1080/10428194.2017.1339879 [OPEN ACCESS]
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Übersichtsarbeit

** Berger, M; Richtig, G; Kashofer, K; Aigelsreiter, A; Richtig, E The window of opportunities for targeted therapy in BRAFwt/NRASwt/KITwt melanoma: biology and clinical implications of fusion proteins and other mutations.
G Ital Dermatol Venereol. 2018; 153(3): 349-360. Doi: 10.23736/S0392-0488.18.05970-9 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Fallbericht

** Graffmann, N; Bohndorf, M; Ncube, A; Wruck, W; Kashofer, K; Zatloukal, K; Adjaye, J Establishment and characterization of an iPSC line from a 58 years old high grade patient with nonalcoholic fatty liver disease (70% steatosis) with homozygous wildtype PNPLA3 genotype.
Stem Cell Res. 2018; 31(4):131-134 Doi: 10.1016/j.scr.2018.07.011 (- Case Report) [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Abstract (Zeitschrift)

** Caraffini, V; Geiger, O; Rosenberger, A; Hatzl, S; Perfler, B; Berg, JL; Lim, C; Strobl, H; Kashofer, K; Hoefler, G; Geissler, K; Kolch, W; Blyth, K; Athineos, D; Wolfler, A; Sill, H; Zebisch, A Loss of RKIP expression is a frequent event in chronic myelomonocytic leukemia and functionally involved in the pathogenesis of this malignancy
ONCOL RES TREAT. 2018; 41: 27-27. [Oral Communication]
Web of Science

 

** Kashofer, K; Halbwedl, I; Winter, E; Hoefler, G; Asslaber, M Expanding on WHO guideline compliant molecular testing of central nervous system tumours by low density whole genome sequencing
VIRCHOWS ARCH. 2018; 473: S28-S28.-ECP European Congress of Pathology; SEP 8-12,2018; Bilbao, SPAIN. [Oral Communication]
Web of Science

 

** Kashofer, K; Thuringer, A; Gorkiewicz, G Broad spectrum pathogen detection (bacteria and fungi) by NGS is a novel measure for tissue based infectious disease diagnostics
VIRCHOWS ARCH. 2018; 473: S25-S25. [Oral Communication]
Web of Science

 

** Kashofer, K; Thuringer, A; Halbwedl, I; Asslaber, M; Wackernagel, W Comprehensive diagnosis and monitoring of uveal melanoma with gene panel analysis, low density whole genome sequencing and digital droplet PCR
VIRCHOWS ARCH. 2018; 473: S28-S29.-ECP European Congress of Pathology; SEP 8-12,2018; Bilbao, SPAIN. [Oral Communication]
Web of Science

 

** Kashofer, K; Winter, E; Reich, O; Hoefler, G; Regauer, S Time series analysis of TP53 gene mutations in recurrent vulvar cancer
VIRCHOWS ARCH. 2018; 473: S33-S33. [Oral Communication]
Web of Science

 

2017

Originalarbeit (Zeitschrift)

** Castellani, C; Singer, G; Kaiser, M; Kaiser, T; Huang, J; Sperl, D; Kashofer, K; Fauler, G; Guertl-Lackner, B; Höfler, G; Till, H Neuroblastoma causes alterations of the intestinal microbiome, gut hormones, inflammatory cytokines, and bile acid composition.
Pediatr Blood Cancer. 2017; 64(8): Doi: 10.1002/pbc.26425
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** Castellani, C; Singer, G; Kashofer, K; Huber-Zeyringer, A; Flucher, C; Kaiser, M; Till, H The Influence of Proton Pump Inhibitors on the Fecal Microbiome of Infants with Gastroesophageal Reflux-A Prospective Longitudinal Interventional Study.
Front Cell Infect Microbiol. 2017; 7:444 Doi: 10.3389/fcimb.2017.00444 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Chen, S; El-Heliebi, A; Tauber, G; Langsenlehner, T; Pötscher, M; Kashofer, K; Czyż, ZT; Polzer, B; Riethdorf, S; Kuske, A; Leitinger, G; Pantel, K; Kroneis, T; Sedlmayr, P Catch and Release: rare cell analysis from a functionalised medical wire.
Sci Rep. 2017; 7(2):43424-43424 Doi: 10.1038/srep43424 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Dandachi, N; Tiran, V; Lindenmann, J; Brcic, L; Fink-Neuboeck, N; Kashofer, K; Absenger, G; Bezan, A; Cote, RJ; Datar, R; Balic, M Frequency and clinical impact of preoperative circulating tumor cells in resectable non-metastatic lung adenocarcinomas.
Lung Cancer. 2017; 113(46):152-157 Doi: 10.1016/j.lungcan.2017.10.003
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** El-Heliebi, A; Kashofer, K; Fuchs, J; Jahn, SW; Viertler, C; Matak, A; Sedlmayr, P; Hoefler, G Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer.
Histochem Cell Biol. 2017; 148(2):105-115 Doi: 10.1007/s00418-017-1557-5 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Heitzer, E; Sunitsch, S; Gilg, MM; Lohberger, B; Rinner, B; Kashofer, K; Stündl, N; Ulz, P; Szkandera, J; Leithner, A; Liegl-Atzwanger, B Expanded molecular profiling of myxofibrosarcoma reveals potentially actionable targets.
Mod Pathol. 2017; 30(12):1698-1709 Doi: 10.1038/modpathol.2017.94 [OPEN ACCESS]
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** Kashofer, K; Regauer, S Analysis of full coding sequence of the TP53 gene in invasive vulvar cancers: Implications for therapy.
GYNECOL ONCOL. 2017; 146(2): 314-318. Doi: 10.1016/j.ygyno.2017.05.018
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** Kashofer, K; Winter, E; Halbwedl, I; Thueringer, A; Kreiner, M; Sauer, S; Regauer, S HPV-negative penile squamous cell carcinoma: disruptive mutations in the TP53 gene are common.
Mod Pathol. 2017; 30(7):1013-1020 Doi: 10.1038/modpathol.2017.26 [OPEN ACCESS]
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** Lal, R; Lind, K; Heitzer, E; Ulz, P; Aubell, K; Kashofer, K; Middeke, JM; Thiede, C; Schulz, E; Rosenberger, A; Hofer, S; Feilhauer, B; Rinner, B; Svendova, V; Schimek, MG; Rücker, FG; Hoefler, G; Döhner, K; Zebisch, A; Wölfler, A; Sill, H Somatic TP53 mutations characterize preleukemic stem cells in acute myeloid leukemia.
Blood. 2017; 129(18): 2587-2591. Doi: 10.1182/blood-2016-11-751008 [OPEN ACCESS]
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** Lohberger, B; Stuendl, N; Leithner, A; Rinner, B; Sauer, S; Kashofer, K; Liegl-Atzwanger, B Establishment of a novel cellular model for myxofibrosarcoma heterogeneity.
Sci Rep. 2017; 7(9):44700-44700 Doi: 10.1038/srep44700 [OPEN ACCESS]
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** Mörkl, S; Lackner, S; Müller, W; Gorkiewicz, G; Kashofer, K; Oberascher, A; Painold, A; Holl, A; Holzer, P; Meinitzer, A; Mangge, H; Holasek, S Gut microbiota and body composition in anorexia nervosa inpatients in comparison to athletes, overweight, obese, and normal weight controls.
Int J Eat Disord. 2017; 50(12):1421-1431 Doi: 10.1002/eat.22801
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** Nizet, S; Muñoz, E; Fiebich, BL; Abuja, PM; Kashofer, K; Zatloukal, K; Tangermann, S; Kenner, L; Tschegg, C; Nagl, D; Scheichl, L; Meisslitzer-Ruppitsch, C; Freissmuth, M; Berger, T Clinoptilolite in Dextran Sulphate Sodium-Induced Murine Colitis: Efficacy and Safety of a Microparticulate Preparation.
Inflamm Bowel Dis. 2017; 24(1):54-66 Doi: 10.1093/ibd/izx042 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Kurzbericht/Letter

** Richtig, G; Richtig, E; Kashofer, K; Koch, L; Winter, G; Hoefler, G; Pichler, M; Ehall, B; Grübler, MR; Heinemann, A; Aigelsreiter, A Testing and clinical implications for non-V600 BRAF mutations in metastatic NRASmt melanoma.
Br J Dermatol. 2017; 177(3):860-861 Doi: 10.1111/bjd.15222
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** Spindelboeck, W; Schulz, E; Uhl, B; Kashofer, K; Aigelsreiter, A; Zinke-Cerwenka, W; Mulabecirovic, A; Kump, PK; Halwachs, B; Gorkiewicz, G; Sill, H; Greinix, H; Högenauer, C; Neumeister, P Repeated fecal microbiota transplantations attenuate diarrhea and lead to sustained changes in the fecal microbiota in acute, refractory gastrointestinal graft-versus-host-disease.
Haematologica. 2017; 102(5):e210-e213-e210-e213 Doi: 10.3324/haematol.2016.154351 (- Case Report) [OPEN ACCESS]
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Übersichtsarbeit

** Richtig, G; Hoeller, C; Kashofer, K; Aigelsreiter, A; Heinemann, A; Kwong, LN; Pichler, M; Richtig, E Beyond the BRAFV600E hotspot: biology and clinical implications of rare BRAF gene mutations in melanoma patients.
Br J Dermatol. 2017; 177(4):936-944 Doi: 10.1111/bjd.15436
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** Szurian, K; Kashofer, K; Liegl-Atzwanger, B Role of Next-Generation Sequencing as a Diagnostic Tool for the Evaluation of Bone and Soft-Tissue Tumors.
Pathobiology. 2017; 84(6):323-338 Doi: 10.1159/000478662 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Caraffini, V; Geiger, O; Rosenberger, A; Hatzl, S; Perfler, B; Berg, JL; Lim, C; Strobl, H; Kashofer, K; Hoefler, G; Geissler, K; Kolch, W; Blyth, K; Athineos, D; Woelfler, A; Sill, H; Zebisch, A LOSS OF RAF KINASE INHIBITOR PROTEIN IS INVOLVED IN MYELOMONOCYTIC LINEAGE COMMITMENT AND AGGRAVATES THE DEVELOPMENT OF CHRONIC MYELOMONOCYTIC LEUKEMIA IN A MURINE IN-VIVO MODEL
HAEMATOLOGICA. 2017; 102: 148-149.-22nd Congress of the European-Hematology-Association; JUN 22-25, 2017; Madrid, SPAIN. [Oral Communication]
Web of Science

 

** Caraffini, V; Schauer, S; Kashofer, K; Wolfler, A; Hoefler, G; Sill, H; Zebisch, A RAF KINASE INHIBITOR PROTEIN IS INVOLVED IN THE DEVELOPMENT OF MYELOID SARCOMA
HAEMATOLOGICA. 2017; 102: 361-362.-22nd Congress of the European-Hematology-Association; JUN 22-25, 2017; Madrid, SPAIN. [Poster]
Web of Science

 

** Gaksch, L; Kashofer, K; Heitzer, E; Daga, S; Hofer, S; Krisper, N; Hofler, G; Zebisch, A; Sill, H; Wolfler, A Persistence of non-DNMT3A mutations predicts relapse in cytogenetically normal AML
ONCOL RES TREAT. 2017; 40: 140-141. [Oral Communication]
Web of Science

 

** Hassan, AM; Mancano, G; Kashofer, K; Fröhlich, EE; Matak, A; Mayerhofer, R; Reichmann, F; Olivares, M; Neyrinck, AM; Delzenne, NM; Claus, SP; Holzer, P High fat diet-induced depression-like behaviour in mice: Roles of intestinal microbiome, neuropeptide Y, and brain metabolome.
NEUROGASTROENT MOTIL. 2017; 29: 27-27.-Neuro GASTRO 2017; AUG 24-26, 2017; Cork, IRELAND. [Poster]
Web of Science

 

** Jačan, A; Zenz, G; Fröhlich, EE; Bordag, N; Magnes, C; Kashofer, K; Mayerhofer, R; Reichmann, F; Holzer, P Disruption of colonic microbiome and circulating metabolome in antibiotic-treated mice.
NEUROGASTROENT MOTIL. 2017; 29: 4-4.-Neuro GASTRO 2017; AUG 24-26, 2017; Cork, IRELAND. [Oral Communication]
Web of Science

 

** Krause, R; Horvath, L; Halwachs-Wenzl, B; Gorkiewicz, G; Kashofer, K; Moissl-Eichinger, C; Koskinen, K; Eisner, F; Vonlewinski, D; Hogenauer, C Mycobiota analysis of samples from different body regions in ICU patients
MYCOSES. 2017; 60: 157-158.Oct 8, 2017; [Poster]
Web of Science

 

** Morkl, S; Lackner, S; Gorkiewicz, G; Kashofer, K; Blesl, C; Tmava, A; Oberascher, A; Holasek, S Interplay of gut microbiota, body mass index and depression scores in anorexia nervosa: Preliminary data
EUR PSYCHIAT. 2017; 41: S92-S92. Doi: 10.1016/j.eurpsy.2017.01.287 [Oral Communication]
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2016

Originalarbeit (Zeitschrift)

** Fröhlich, EE; Farzi, A; Mayerhofer, R; Reichmann, F; Jačan, A; Wagner, B; Zinser, E; Bordag, N; Magnes, C; Fröhlich, E; Kashofer, K; Gorkiewicz, G; Holzer, P Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication.
Brain Behav Immun. 2016; 56(6):140-155 Doi: 10.1016/j.bbi.2016.02.020 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Jahn, SW; Kashofer, K; Thüringer, A; Abete, L; Winter, E; Eidenhammer, S; Viertler, C; Tavassoli, F; Moinfar, F Mutation Profiling of Usual Ductal Hyperplasia of the Breast Reveals Activating Mutations Predominantly at Different Levels of the PI3K/AKT/mTOR Pathway.
Am J Pathol. 2016; 186(1):15-23 Doi: 10.1016/j.ajpath.2015.09.004 [OPEN ACCESS]
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** Krause, R; Halwachs, B; Thallinger, GG; Klymiuk, I; Gorkiewicz, G; Hoenigl, M; Prattes, J; Valentin, T; Heidrich, K; Buzina, W; Salzer, HJ; Rabensteiner, J; Prüller, F; Raggam, RB; Meinitzer, A; Moissl-Eichinger, C; Högenauer, C; Quehenberger, F; Kashofer, K; Zollner-Schwetz, I Characterisation of Candida within the Mycobiome/Microbiome of the Lower Respiratory Tract of ICU Patients.
PLoS One. 2016; 11(5):e0155033-e0155033 Doi: 10.1371/journal.pone.0155033 [OPEN ACCESS]
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** Sunitsch, S; Gilg, M; Kashofer, K; Leithner, A; Liegl-Atzwanger, B; Beham-Schmid, C Case Report: Epstein-Barr-Virus negative diffuse large B-cell lymphoma detected in a peri-prosthetic membrane.
Diagn Pathol. 2016; 11(1):80-80 Doi: 10.1186/s13000-016-0533-z (- Case Report) [OPEN ACCESS]
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** Ulz, P; Thallinger, GG; Auer, M; Graf, R; Kashofer, K; Jahn, SW; Abete, L; Pristauz, G; Petru, E; Geigl, JB; Heitzer, E; Speicher, MR Inferring expressed genes by whole-genome sequencing of plasma DNA.
Nat Genet. 2016; 48(10):1273-1278 Doi: 10.1038/ng.3648
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** Zebisch, A; Lal, R; Müller, M; Lind, K; Kashofer, K; Girschikofsky, M; Fuchs, D; Wölfler, A; Geigl, JB; Sill, H Acute myeloid leukemia with TP53 germ line mutations.
Blood. 2016; 128(18): 2270-2272. Doi: 10.1182/blood-2016-08-732610 [OPEN ACCESS]
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Fallbericht

** Richtig, G; Aigelsreiter, A; Kashofer, K; Talakic, E; Kupsa, R; Schaider, H; Richtig, E Two Case Reports of Rare BRAF Mutations in Exon 11 and Exon 15 with Discussion of Potential Treatment Options.
Case Rep Oncol. 2016; 9(3):543-546 Doi: 10.1159/000449125 (- Case Report) [OPEN ACCESS]
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Abstract (Zeitschrift)

** Brodowicz, T; Liegl-Atzwanger, B; Tresch-Bruneel, E; Bogart, E; Mir, O; Blay, JY; Kashofer, K; Le Cesne, A; Hamacher, R; Penel, N Regorafenib (R) versus placebo (P) in soft tissue sarcomas (STS): analysis of genetic prognostic and predictive factors
ANN ONCOL. 2016; 27: Doi: 10.1093/annonc/mdw388.10 [Oral Communication]
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** Gaksch, L; Kashofer, K; Heitzer, E; Daga, S; Hofer, S; Krisper, N; Höfler, G; Zebisch, A; Sill, H; Wölfler A Persitence of non-DNMT3A mutations predicts relapse in cytogenetically normal AML.
Oncol Res Treat 2016. 2016; 39(suppl3):140--Jahrestagung DGHO; OCT 14-18,2016; Leipzig. (ISBN: 2296-5270 ) [Oral Communication]
Web of Science

 

** Kashofer, K; Brcic, L; Thueringer, A; Aigelsreiter, A; Popper, H; Hoefler, G Liquid biopsies in lung and skin cancer-a comparison of digital PCR and NGS methodologies
VIRCHOWS ARCH. 2016; 469: S42-S42. [Oral Communication]
Web of Science

 

** Kashofer, K; Jahn, S; Halbwedl, I; Hoetler, G Beyond BRCA-HRD scoring using Affymetrix Oncoscan microarrays
VIRCHOWS ARCH. 2016; 469: S203-S203. [Poster]
Web of Science

 

** Richtig, G; Ehall, B; Koch, L; Richtig, E; Winter, G; Eder, S; Kashofer, K; Heinemann, A; Hoefler, G; Aigelsreiter, A The clinical relevance of testing for non-V600E BRAF mutations in melanoma-a single center experience
VIRCHOWS ARCH. 2016; 469: S309-S309. [Oral Communication]
Web of Science

 

** Riding, G; Ehall, B; Koch, L; Richtig, E; Winter, G; Eder, S; Kashofer, K; Heinemann, A; Hoefler, G; Aigelsreiter, A The relevance of BRAF exon 11 testing in melanoma-single center experience
VIRCHOWS ARCH. 2016; 469: S193-S193. [Poster]
Web of Science

 

2015

Originalarbeit (Zeitschrift)

** Jahn, SW; Kashofer, K; Halbwedl, I; Winter, G; El-Shabrawi-Caelen, L; Mentzel, T; Hoefler, G; Liegl-Atzwanger, B Mutational dichotomy in desmoplastic malignant melanoma corroborated by multigene panel analysis.
Mod Pathol. 2015; 28(7):895-903 Doi: 10.1038/modpathol.2015.39 [OPEN ACCESS]
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** Ravindran Menon, D; Das, S; Krepler, C; Vultur, A; Rinner, B; Schauer, S; Kashofer, K; Wagner, K; Zhang, G; Bonyadi Rad, E; Haass, NK; Soyer, HP; Gabrielli, B; Somasundaram, R; Hoefler, G; Herlyn, M; Schaider, H A stress-induced early innate response causes multidrug tolerance in melanoma.
Oncogene. 2015; 34(34):4448-4459 Doi: 10.1038/onc.2014.372 [OPEN ACCESS]
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** Wruck, W; Kashofer, K; Rehman, S; Daskalaki, A; Berg, D; Gralka, E; Jozefczuk, J; Drews, K; Pandey, V; Regenbrecht, C; Wierling, C; Turano, P; Korf, U; Zatloukal, K; Lehrach, H; Westerhoff, HV; Adjaye, J Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes.
Sci Data. 2015; 2(S 01):150068-150068 Doi: 10.1038/sdata.2015.68 [OPEN ACCESS]
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Kurzbericht/Letter

** Geiger, O; Hatzl, S; Kashofer, K; Hoefler, G; Wölfler, A; Sill, H; Zebisch, A Deletion of SPRY4 is a frequent event in secondary acute myeloid leukemia.
Ann Hematol. 2015; 94(11):1923-1924 Doi: 10.1007/s00277-015-2445-5 [OPEN ACCESS]
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** Schulz, E; Kashofer, K; Heitzer, E; Mhatre, KN; Speicher, MR; Hoefler, G; Sill, H Preexisting TP53 mutation in therapy-related acute myeloid leukemia.
Ann Hematol. 2015; 94(3):527-529 Doi: 10.1007/s00277-014-2191-0 (- Case Report) [OPEN ACCESS]
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Abstract (Zeitschrift)

** Kashofer, K; Thuringer, A; Sauer, S; Gorkiewicz, G A complete workflow for diagnostic microbiome analysis using Ion Torrent PGM and QIIME
VIRCHOWS ARCH. 2015; 467: S46-S47.-27th European Congress of Pathology; SEP 5 - 9, 2015; [Oral Communication]
Web of Science

 

** Kashofer, K; Winter, E; Halbwedl, I; Thuringer, A; Regauer, S High incidence of TP53 mutations in HPV-negative penile carcinomas revealed by NGS analysis
VIRCHOWS ARCH. 2015; 467: S22-S22.-27th European Congress of Pathology; SEP 5 - 9, 2015; Belgrade, SERBIA. [Oral Communication]
Web of Science

 

** Matak, A; Jahn, S; Viertler, C; Thuringer, A; Halbwedl, I; Langner, C; Hoefler, G; Kashofer, K Genetic heterogeneity of colorectal carcinoma in NGS analysis: A complication for molecular diagnosis?
VIRCHOWS ARCH. 2015; 467: S166-S167.-European Congress of Pathology; SEP 5-9, 2015; Belgrade, SERBIA. [Poster]
Web of Science

 

** Menon, D; Das, S; Krepler, C; Vultur, A; Schauer, S; Kashofer, K; Haass, NK; Soyer, HP; Gabrielli, B; Somasundaram, R; Hoefler, G; Herlyn, M; Schaider, H A stress induced early innate response causes multi-drug tolerance in melanoma
EXP DERMATOL. 2015; 24(3):E35-E35.-42nd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF); MAR 05-07, 2015; Ulm, GERMANY. [Oral Communication]
Web of Science

 

** Regauer, S; Kashofer, K A MAJORITY BUT NOT ALL HPV-NEGATIVE VULVAR SQUAMOUS CELL CARCINOMAS HARBOR P53 GENE MUTATIONS
INT J GYNECOL CANCER. 2015; 25(9):682-682. [Oral Communication]
Web of Science

 

2014

Originalarbeit (Zeitschrift)

** Pandey, V; Sultan, M; Kashofer, K; Ralser, M; Amstislavskiy, V; Starmann, J; Osprian, I; Grimm, C; Hache, H; Yaspo, ML; Sültmann, H; Trauner, M; Denk, H; Zatloukal, K; Lehrach, H; Wierling, C Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains.
PLoS One. 2014; 9(10):e111006-e111006 Doi: 10.1371/journal.pone.0111006 [OPEN ACCESS]
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** Schulz, E; Klampfl, P; Holzapfel, S; Janecke, AR; Ulz, P; Renner, W; Kashofer, K; Nojima, S; Leitner, A; Zebisch, A; Wölfler, A; Hofer, S; Gerger, A; Lax, S; Beham-Schmid, C; Steinke, V; Heitzer, E; Geigl, JB; Windpassinger, C; Hoefler, G; Speicher, MR; Boland, CR; Kumanogoh, A; Sill, H Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.
Nat Commun. 2014; 5(10):5191-5191 Doi: 10.1038/ncomms6191 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Menon, DR; Das, S; Krepler, C; Vultur, A; Rinner, B; Schauer, S; Kashofer, K; Wagner, K; Zhang, G; Rad, EB; Soyer, HP; Gabrielli, B; Somasundaram, R; Hoefler, G; Herlyn, M; Schaider, H A stress induced early innate response causes multi-drug tolerance in melanoma
EUR J CANCER. 2014; 50: 34-34. Doi: 10.1016/S0959-8049(14)70219-9 [Poster]
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** Schulz, E; Kashofer, K; Mhatre, KN; Höfler, G; Sill, H SELECTION OF A PRE-EXISTING TP53 MUTATED CLONE IN THERAPY-RELATED ACUTE MYELOID LEUKEMIA
Haematologica. 2014; 99(S1):15-15.-19th Congress of the European Hematology Association; JUNE 12-15, 2014; Milan, ITALY. [Poster]
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** Schulz, E; Klampfl, P; Holzapfel, S; Janecke, AR; Ulz, P; Renner, W; Kashofer, K; Najima, S; Leitner, A; Zebisch, A; Wölfler, A; Hofer, S; Gerger, A; Lax, S; Beham-Schmid, C; Steinke, V; Geigl, JB; Höfler, G; Speicher, MR; Boland, CR; Kumanogoh, A; Sill, H Germline variants in the semaphorin SEMA4A confer susceptibility to familial colorectal cancer type X
Oncol Res Treat. 2014; 37(S5):105-105.-Annual Meeting of the German, Austrian and Swiss Associations of Hematology and Medical Oncology; OCT 10-14, 2014; Hamburg, GERMANY. (ISBN: 978-3-318-02811-9 ) [Oral Communication]
Web of Science

 

2013

Originalarbeit (Zeitschrift)

** Fogeron, ML; Muller, H; Schade, S; Dreher, F; Lehmann, V; Kuhnel, A; Scholz, AK; Kashofer, K; Zerck, A; Fauler, B; Lurz, R; Herwig, R; Zatloukal, K; Lehrach, H; Gobom, J; Nordhoff, E; Lange, BMH; LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.
NAT COMMUN. 2013; 4(2): 1531-1531. Doi: 10.1038/ncomms2517 [OPEN ACCESS]
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** Kashofer, K; Viertler, C; Pichler, M; Zatloukal, K Quality control of RNA preservation and extraction from paraffin-embedded tissue: implications for RT-PCR and microarray analysis.
PLoS One. 2013; 8(7):e70714-e70714 Doi: 10.1371/journal.pone.0070714 [OPEN ACCESS]
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** Partl, C; Lex, A; Streit, M; Kalkofen, D; Kashofer, K; Schmalstieg, D enRoute: dynamic path extraction from biological pathway maps for exploring heterogeneous experimental datasets.
BMC Bioinformatics. 2013; 14 Suppl 19(3):S3-S3 Doi: 10.1186/1471-2105-14-S19-S3 [OPEN ACCESS]
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** Röhr, C; Kerick, M; Fischer, A; Kühn, A; Kashofer, K; Timmermann, B; Daskalaki, A; Meinel, T; Drichel, D; Börno, ST; Nowka, A; Krobitsch, S; McHardy, AC; Kratsch, C; Becker, T; Wunderlich, A; Barmeyer, C; Viertler, C; Zatloukal, K; Wierling, C; Lehrach, H; Schweiger, MR High-throughput miRNA and mRNA sequencing of paired colorectal normal, tumor and metastasis tissues and bioinformatic modeling of miRNA-1 therapeutic applications.
PLoS One. 2013; 8(7):e67461-e67461 Doi: 10.1371/journal.pone.0067461 [OPEN ACCESS]
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2012

Originalarbeit (Zeitschrift)

** Jozefczuk, J; Kashofer, K; Ummanni, R; Henjes, F; Rehman, S; Geenen, S; Wruck, W; Regenbrecht, C; Daskalaki, A; Wierling, C; Turano, P; Bertini, I; Korf, U; Zatloukal, K; Westerhoff, HV; Lehrach, H; Adjaye, J A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells.
Front Physiol. 2012; 3(12):339-339 Doi: 10.3389/fphys.2012.00339 [OPEN ACCESS]
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** Viertler, C; Groelz, D; Gündisch, S; Kashofer, K; Reischauer, B; Riegman, PH; Winther, R; Wyrich, R; Becker, KF; Oelmüller, U; Zatloukal, K A New Technology for Stabilization of Biomolecules in Tissues for Combined Histological and Molecular Analyses.
J Mol Diagn. 2012; 14(5):458-466 Doi: 10.1016/j.jmoldx.2012.05.002 [OPEN ACCESS]
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2011

Originalarbeit (Zeitschrift)

** Mahajan, V; Klingstedt, T; Simon, R; Nilsson, KP; Thueringer, A; Kashofer, K; Haybaeck, J; Denk, H; Abuja, PM; Zatloukal, K Cross β-sheet conformation of keratin 8 is a specific feature of Mallory-Denk bodies compared with other hepatocyte inclusions.
Gastroenterology. 2011; 141(3):1080-1090.e1-1080-1090.e7 Doi: 10.1053/j.gastro.2011.05.039
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Abstract (Zeitschrift)

** Nikam, A; Schock, E; Kashofer, K; Lackner, K; Zatloukal, K; Abuja, PM PPAR alpha and Nrf2 Govern Metabolic Deregulation and Oxidative Stress in a Murine Model for Nonalcoholic Steatohepatitis (NASH)
FREE RADICAL BIO MED. 2011; 51: S64-S64.-18th Annual Meeting of the Society-for-Free-Radical-Biology-and-Medicine (SFRBM); NOV 16-20, 2011; Atlanta, GA. Doi: 10.1016/j.freeradbiomed.2011.10.166 [Oral Communication]
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** Viertler, C; Groelz, D; Kashofer, K; Gundisch, S; Riegman, P; Winther, R; Wyrich, R; Kruhoffer, M; Becker, KF; Oelmuller, U; Zatloukal, K A new technology for simultaneous preservation of biomolecules and morphology in tissues.
VIRCHOWS ARCH. 2011; 459: S318-S318.-23rd European Congress of Pathology.; AUG 27- SEP 1, 2011; Helsinki, FINLAND. [Poster]
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** Viertler, C; Groelz, D; Kashofer, K; Wyrich, R; Oelmueller, U; Zatloukal, K PRE-ANALYTICAL PARAMETERS IMPACTING ON TISSUE-BASED BIOMARKERS
CLIN CHEM LAB MED. 2011; 49: S126-S126. [Oral Communication]
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2010

Originalarbeit (Zeitschrift)

** Lex, A; Streit, M; Partl, C; Kashofer, K; Schmalstieg, D Comparative analysis of multidimensional, quantitative data.
IEEE TRANS VISUAL COMPUT GR. 2010; 16(6): 1027-1035. Doi: 10.1109/TVCG.2010.138
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Abstract (Zeitschrift)

** Mahajan, VS; Klingstedt, T; Nilsson, KPR; Fuchsbichler, A; Kashofer, K; Abuja, PM; Denk, H; Zatloukal, K STRUCTURAL CHARACTERISTICS OF MISFOLDED PROTEINS IN LIVER DISEASE: EVIDENCE FOR CROSS beta-SHEET CONFORMATION IN MALLORY-DENK BODIES BUT NOT IN OTHER HEPATOCYTIC AGGREGATES
J HEPATOL. 2010; 52: S308-S308.-45th Annual Meeting of the European Association for the Study of the Liver.; April14-18,2010; Vienna. Doi: 10.1016/S0168-8278(10)60794-5 [Poster]
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** Reinisch, A; Hofmann, N; Obenauf, A; Karl, K; Rohde, E; Schallmoser, K; Thaler, D; Fruhwirth, M; Flicker, K; Linkesch, W; Speicher, M; Strunk, D STABLE VESSEL GENERATION TROUGH APPLICATION OF BLOOD-DERIVED ENDOTHELIAL COLONY FORMING PROGENITOR CELLS (ECFCS) AND MESENCHYMAL STROMAL/STEM CELLS (MSCS)
HAEMATOL-HEMATOL J. 15th Congress of the European Hematology Association. 2010; 95(s2):0509-220.-15th Congress of the European Hematology Association. ; JUN 10-13, 2010; Barcelona, SPAIN. [Oral Communication]
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** Reinisch, A; Hofmann, NA; Obenauf, A; Kashofer, K; Rohde, E; Schallmoser, K; Thaler, D; Fruhwirth, M; Flicker, K; Linkesch, W; Speicher, M; Strunk, D Sustained vessel formation through co-transplantation of endothelial colony-forming progenitor cells with mesenchymal stromal cells
BONE MARROW TRANSPLANT. 2010; 45: S52-S52. -36th Annual Meeting of the European Group for Blood and Marrow Transplantation; MAR 21-24, 2010; Vienna, AUSTRIA. [Oral Communication]
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2009

Originalarbeit (Zeitschrift)

** Reinisch, A; Hofmann, NA; Obenauf, AC; Kashofer, K; Rohde, E; Schallmoser, K; Flicker, K; Lanzer, G; Linkesch, W; Speicher, MR; Strunk, D Humanized large-scale expanded endothelial colony-forming cells function in vitro and in vivo.
Blood. 2009; 113(26): 6716-6725. Doi: 10.1182/blood-2008-09-181362 [OPEN ACCESS]
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Übersichtsarbeit

** Kashofer, K; Tschernatsch, MM; Mischinger, HJ; Iberer, F; Zatloukal, K The disease relevance of human hepatocellular xenograft models: molecular characterization and review of the literature.
Cancer Lett. 2009; 286(1):121-128 Doi: 10.1016/j.canlet.2008.11.011
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Abstract (Zeitschrift)

** Reinisch, A; Hofmann, NA; Obenauf, A; Kashofer, K; Rohde, E; Schallmoser, K; Thaler, D; Fruehwirth, M; Flicker, K; Linkesch, W; Speicher, M; Strunk, D Vascular regeneration by adult blood-derived endothelial colony-forming cells expanded under animal serum-free conditions
BONE MARROW TRANSPLANT. 35th Annual Meeting of the European Group for Blood and Marrow Transplantation2009; 43(1):S19-S20.-35th Annual Meeting of the European Group for Blood and Marrow Transplantation; MAR 29-APR 01, 2009; Goteborg, SWEDEN. [Oral Communication]
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2008

Originalarbeit (Zeitschrift)

** Streit, M; Kalkusch, M; Kashofer, K; Schmalstieg, D Navigation and exploration of interconnected pathways
COMPUTER GRAPHICS FORUM. 2008; 27(3): 951-958. Doi: 10.1111/j.1467-8659.2008.01229.x
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Abstract (Zeitschrift)

** Reinisch, A; Hofmann, NA; Obenauf, A; Kashofer, K; Rohde, E; Schallmoser, K; Thaler, D; Fruehwirth, M; Linkesch, W; Speicher, M; Strunk, D Making Functional Endothelial Progenitors: Humanized Large-scale Animal Serum-free Propagated Adult Blood-derived Endothelial Colony-forming Cells Assemble Stable Perfused Vessels In vivo.
Fiftieth Annual Meeting Abstracts2008; 112(11):659-659.-American Society of Hematology 50th Annual Meeting and Exposition; DEC 6-9, 2008; San Francisco, USA. [Poster]
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2007

Originalarbeit (Zeitschrift)

** Schallmoser, K; Bartmann, C; Rohde, E; Reinisch, A; Kashofer, K; Stadelmeyer, E; Drexler, C; Lanzer, G; Linkesch, W; Strunk, D Human platelet lysate can replace fetal bovine serum for clinical-scale expansion of functional mesenchymal stromal cells.
Transfusion. 2007; 47(8): 1436-1446. Doi: 10.1111/j.1537-2995.2007.01220.x
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** Siapati, EK; Bigger, BW; Kashofer, K; Themis, M; Thrasher, AJ; Bonnet, D Murine leukemia following irradiation conditioning for transplantation of lentivirally-modified hematopoietic stem cells.
Eur J Haematol. 2007; 78(4): 303-313. Doi: 10.1111/j.1600-0609.2006.00813.x
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Abstract (Zeitschrift)

** Schallmoser, K; Bartmann, C; Rohde, E; Reinisch, A; Kashofer, K; Emberger, W; Lanzer, G; Linkesch, W; Strunk, D A novel system for highly efficient clinical scale propagation of human mesenchymal stem cells with human platelet lysate
HAEMATOL-HEMATOL J. 2007; 92: 317-318.-12th Congress of the European Hematology Association; JUN 7-10, 2007; Vienna, AUSTRIA. [Poster]
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** Schallmoser, K; Malischnik, C; Rohde, E; Reinisch, A; Kashofer, K; Lanzer, G; Linkesch, W; Strunk, D Two steps to clinical multipotent mesenchymal stromal cells with human platelet lysate
BONE MARROW TRANSPLANT. 2007; 39: S110-S110. [Poster]
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** Schallmoser, K; Reinisch, A; Bartmann, C; Rohde, E; Kashofer, K; Emberger, W; Lanzer, G; Linkesch, W; Strunk, D Animal serum-free clinical scale propagation of human MSC
TRANSFUSION. 2007; 47(3):28A-28A.-American Association of Blood Banks (AABB) 60th Annual Meeting; OKT 20-23, 2007; Anaheim, California, USA. [Oral Communication]
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2006

Originalarbeit (Zeitschrift)

** Kashofer, K; Siapati, EK; Bonnet, D In vivo formation of unstable heterokaryons after liver damage and hematopoietic stem cell/progenitor transplantation.
Stem Cells. 2006; 24(4): 1104-1112. Doi: 10.1634/stemcells.2005-0405 [OPEN ACCESS]
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2005

Übersichtsarbeit

** Kashofer, K; Bonnet, D Gene therapy progress and prospects: stem cell plasticity.
Gene Ther. 2005; 12(16): 1229-1234. Doi: 10.1038/sj.gt.3302571 [OPEN ACCESS]
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